Archive for the ‘intellectual property’ Category

Extending memristive theory

Monday, April 29th, 2013

This is kind of fascinating. A German research team based at JARA (Jülich Aachen Research Alliance) is suggesting that memristive theory be extended beyond passive components in their paper about Resistive Memory Cells (ReRAM) which was recently published in Nature Communications. From the Apr. 26, 2013 news item on Azonano,

Resistive memory cells (ReRAM) are regarded as a promising solution for future generations of computer memories. They will dramatically reduce the energy consumption of modern IT systems while significantly increasing their performance.

Unlike the building blocks of conventional hard disk drives and memories, these novel memory cells are not purely passive components but must be regarded as tiny batteries. This has been demonstrated by researchers of Jülich Aachen Research Alliance (JARA), whose findings have now been published in the prestigious journal Nature Communications. The new finding radically revises the current theory and opens up possibilities for further applications. The research group has already filed a patent application for their first idea on how to improve data readout with the aid of battery voltage.

The Apr. 23, 2013 JARA news release, which originated the news item, provides some background information about data memory before going on to discuss the ReRAMs,

Conventional data memory works on the basis of electrons that are moved around and stored. However, even by atomic standards, electrons are extremely small. It is very difficult to control them, for example by means of relatively thick insulator walls, so that information will not be lost over time. This does not only limit storage density, it also costs a great deal of energy. For this reason, researchers are working feverishly all over the world on nanoelectronic components that make use of ions, i.e. charged atoms, for storing data. Ions are some thousands of times heavier that electrons and are therefore much easier to ‘hold down’. In this way, the individual storage elements can almost be reduced to atomic dimensions, which enormously improves the storage density.

Here’s how the ions behave in ReRAMs (from the news release),

In resistive switching memory cells (ReRAMs), ions behave on the nanometre scale in a similar manner to a battery. The cells have two electrodes, for example made of silver and platinum, at which the ions dissolve and then precipitate again. This changes the electrical resistance, which can be exploited for data storage. Furthermore, the reduction and oxidation processes also have another effect. They generate electric voltage. ReRAM cells are therefore not purely passive systems – they are also active electrochemical components. Consequently, they can be regarded as tiny batteries whose properties provide the key to the correct modelling and development of future data storage.

In complex experiments, the scientists from Forschungszentrum Jülich and RWTH Aachen University determined the battery voltage of typical representatives of ReRAM cells and compared them with theoretical values. This comparison revealed other properties (such as ionic resistance) that were previously neither known nor accessible. “Looking back, the presence of a battery voltage in ReRAMs is self-evident. But during the nine-month review process of the paper now published we had to do a lot of persuading, since the battery voltage in ReRAM cells can have three different basic causes, and the assignment of the correct cause is anything but trivial,” says Dr. Ilia Valov, the electrochemist in Prof. Rainer Waser’s research group.

This discovery could lead to optimizing ReRAMs and exploiting them in new applications (from the news release),

“The new findings will help to solve a central puzzle of international ReRAM research,” says Prof. Rainer Waser, deputy spokesman of the collaborative research centre SFB 917 ‘Nanoswitches’ established in 2011. In recent years, these puzzling aspects include unexplained long-term drift phenomena or systematic parameter deviations, which had been attributed to fabrication methods. “In the light of this new knowledge, it is possible to specifically optimize the design of the ReRAM cells, and it may be possible to discover new ways of exploiting the cells’ battery voltage for completely new applications, which were previously beyond the reach of technical possibilities,” adds Waser, whose group has been collaborating for years with companies such as Intel and Samsung Electronics in the field of ReRAM elements.

The part I found most interesting, given my interest in memristors, is this bit about extending the memristor theory, from the news release,

The new finding is of central significance, in particular, for the theoretical description of the memory components. To date, ReRAM cells have been described with the aid of the concept of memristors – a portmanteau word composed of “memory” and “resistor”. The theoretical concept of memristors can be traced back to Leon Chua in the 1970s. It was first applied to ReRAM cells by the IT company Hewlett-Packard in 2008. It aims at the permanent storage of information by changing the electrical resistance. The memristor theory leads to an important restriction. It is limited to passive components. “The demonstrated internal battery voltage of ReRAM elements clearly violates the mathematical construct of the memristor theory. This theory must be expanded to a whole new theory – to properly describe the ReRAM elements,” says Dr. Eike Linn, the specialist for circuit concepts in the group of authors. [emphases mine] This also places the development of all micro- and nanoelectronic chips on a completely new footing.

Here’s a link to and a citation for the paper,

Nanobatteries in redox-based resistive switches require extension of memristor theory by I. Valov,  E. Linn, S. Tappertzhofen,  S. Schmelzer,  J. van den Hurk,  F. Lentz,  & R. Waser. Nature Communications 4, Article number: 1771 doi:10.1038/ncomms2784 Published 23 April 2013

This paper is open access (as of this writing).

Here’s a list of my 2013 postings on memristors and memristive devices,

2.5M Euros for Ireland’s John Boland and his memristive nanowires (Apr. 4, 2013 posting)

How to use a memristor to create an artificial brain (Feb. 26, 2013 posting)

CeNSE (Central Nervous System of the Earth) and billions of tiny sensors from HP plus a memristor update (Feb. 7, 2013 posting)

For anyone who cares to search the blog, there are several more.

Intellectual property, innovation, and hindrances

Thursday, March 28th, 2013

I have written many, many times about intellectual property and its stifling of innovation; my Oct. 31, 2011 posting titled, Patents as weapons and obstacles, probably rates as one of the more forthright pieces.

It seems that the argument (undertaken by many, many individuals and groups who have been tackling this issue for years before I ever heard it) is making itself felt amongst economists if this Mar. 27, 2013 news release on EurekAlert is to be believed,

A recent study published in the Journal of Political Economy suggests that some types of intellectual property rights discourage subsequent scientific research.

“The goal of intellectual property rights – such as the patent system – is to provide incentives for the development of new technologies. [emphases mine] However, in recent years many have expressed concerns that patents may be impeding innovation if patents on existing technologies hinder subsequent innovation,” said Heidi Williams, author of the study. “We currently have very little empirical evidence on whether this is a problem in practice.”

Williams investigated the sequencing of the human genome by the public Human Genome Project and the private firm Celera. Genes sequenced first by Celera were covered by a contract law-based form of intellectual property, whereas genes sequenced first by the Human Genome Project were placed in the public domain. Although Celera’s intellectual property lasted a maximum of two years, it enabled Celera to sell its data for substantial fees and required firms to negotiate licensing agreements with Celera for any resulting commercial discoveries.

By linking a number of different datasets that had not previously been used by researchers, Williams was able to measure when genes were sequenced, which genes were held by Celera’s intellectual property, and what subsequent investments were made in scientific research and product development on each gene. Williams’ conclusion points to a persistent 20-30 percent reduction in subsequent scientific research and product development for those genes held by Celera’s intellectual property.

“My take-away from this evidence is that – at least in some contexts – intellectual property can have substantial costs in terms of hindering subsequent innovation,” said Williams. “The fact that these costs were – in this context – ‘large enough to care about’ motivates wanting to better understand whether alternative policy tools could be used to achieve a better outcome. …

The Journal of Political Economy is publishing this research, is a University of Chicago Press journal which I expect adds a little cachet to the endeavour. Here’s a citation from the news release,

Heidi L. Williams, “Intellectual Property Rights and Innovation: Evidence from the Human Genome.” Journal of Political Economy 121:1 (publishing in February 2013 issue–due to release in April).

Why is Toronto (Canada) company Integran announcing a new patent?

Thursday, March 7th, 2013

Perhaps I have this backwards but it seems to me that announcing a patent isn’t an especially exciting business or technology event. Nonetheless, Toronto-based Integran’s latest patent is mentioned in a Mar. 7, 2013 news item on Azonano,

 Toronto-based Integran Technologies Inc. (Integran) today announced further advances in its “structural metal plating-on-polymer” technology (Nanovate™ NP) for enhancing fuel efficiency and reducing greenhouse gas emissions by enabling the cost-effective manufacture of lightweight transportation parts. [emphasis mine]

Under development for several years, Integran’s nanometal-polymer hybrid core technology is protected by a number of patent filings including US 8,367,170 which issued on Feb 5, 2013 and EP 2,193,664 which issued on Feb 20, 2013 disclosing lightweight metal-coated polymer electric and electronic housings for use, e.g., in automotive electronic control units (ECUs).

Integran’s Vice President of Intellectual Property Klaus Tomantschger stated, “We are pleased that our developments relating to structural plating-on-polymer parts have been recognized in the patent jurisdictions of Europe and the United States as these remain dominant regions for advanced automotive technology development.” [emphasis mine]

How does getting a patent advance the technology as the company states in the opening sentence of the news item? Perhaps someone could relieve my ignorance by leaving a comment explaining how this works.

Meanwhile, the Integran news blog’s Mar. 7, 2013 posting states the patents are meant for ‘protection’ (Note: A link has been removed),

Today we announced another series of issued patents that protect our “structural plating on plastic” Nanovate NP platform.  [emphasis mine] This approach is used to create lightweight, structural, EMI and magnetic shielded housings for electronics using an injection molded, machined, or rapid prototyped polymer with a structural Nanovate metal electroplated cladding on the outer surface.

While the patents are geared towards the transportation industry, this approach has value for any application where there is weight sensitivity, but a durable, structural part is required. As an example, hand held medical devices used in hospitals, or ruggedized hand held military electronics are good examples of other applications where this Nanovate metal structural plating could provide a durability part while also providing a part weight reduction.

I have a special interest in this company, since as a Canadian taxpayer, I, and millions others of us, have an investment in it as per my April 16, 2012 posting about the Canadian government’s ‘venture capital’ program and its Integran investment.

Chad Mirkin, spherical nucleic acids, and a new ‘periodic table’

Tuesday, February 19th, 2013

There was a big splash in July 2012 with the announcement that Chad Mirkin’s team at Northwestern University (Chicago, Illinois) had devised a skin cream that penetrated the skin barrier to deliver medication (my July 4, 2012 posting),

A team led by a physician-scientist and a chemist — from the fields of dermatology and nanotechnology — is the first to demonstrate the use of commercial moisturizers to deliver gene regulation technology that has great potential for life-saving therapies for skin cancers.

The topical delivery of gene regulation technology to cells deep in the skin is extremely difficult because of the formidable defenses skin provides for the body. The Northwestern approach takes advantage of drugs consisting of novel spherical arrangements of nucleic acids. These structures, each about 1,000 times smaller than the diameter of a human hair, have the unique ability to recruit and bind to natural proteins that allow them to traverse the skin and enter cells.

Mirkin has just finished presenting (Feb. 15, 2013 and Feb. 17, 2013) more information about spherical nucleic acids and their implications at the AAAS  (American Association for the Advancement of Science) 2013 meeting in Boston, Massachusetts. From the Feb. 15, 2013 news release on EurekAlert,

Northwestern University’s Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).

Potential applications include using SNAs to carry nucleic acid-based therapeutics to the brain for the treatment of glioblastoma, the most aggressive form of brain cancer, as well as other neurological disorders such as Alzheimer’s and Parkinson’s diseases. Mirkin is aggressively pursuing treatments for such diseases with Alexander H. Stegh, an assistant professor of neurology at Northwestern’s Feinberg School of Medicine.

“These structures are really quite spectacular and incredibly functional,” Mirkin said. “People don’t typically think about DNA in spherical form, but this novel arrangement of nucleic acids imparts interesting chemical and physical properties that are very different from conventional nucleic acids.”

Spherical nucleic acids consist of densely packed, highly oriented nucleic acids arranged on the surface of a nanoparticle, typically gold or silver.  [emphasis mine] The tiny non-toxic balls, each roughly 15 nanometers in diameter, can do things the familiar but more cumbersome double helix can’t do:

  • SNAs can naturally enter cells and effect gene knockdown, making SNAs a superior tool for treating genetic diseases using gene regulation technology.
  • SNAs can easily cross formidable barriers in the human body, including the blood-brain barrier and the layers that make up skin.
  • SNAs don’t elicit an immune response, and they resist degradation, resulting in longer lifetimes in the body.

“The field of medicine needs new constructs and strategies for treating disease,” Mirkin said. “Many of the ways we treat disease are based on old methods and materials. Nanotechnology offers the ability to rapidly create new structures with properties that are very different from conventional forms of matter.”

“We now can go after a whole new set of diseases,” Mirkin said. “Thanks to the Human Genome Project and all of the genomics research over the last two decades, we have an enormous number of known targets. And we can use the same tool for each, the spherical nucleic acid. We simply change the sequence to match the target gene. That’s the power of gene regulation technology.”

###

A member of President Obama’s Council of Advisors on Science and Technology, Mirkin is known for invention and development of biological and chemical diagnostic systems based upon nanomaterials. He is the inventor and chief developer of Dip-Pen Nanolithography, a groundbreaking nanoscale fabrication and analytical tool, and is the founder of four Chicago-based companies: AuraSense, AuraSense Therapeutics, Nanosphere and NanoInk.

Mirkin, in addition to his work with spherical nucleic acids, has been busy with other nanoparticles and possible dreams of a new ‘periodic table of elements’, from the Feb. 17, 2013 news release on EurekAlert,

Forging a new periodic table using nanostructures

Northwestern University’s Chad A. Mirkin, …, has developed a completely new set of building blocks that is based on nanoparticles and DNA. Using these tools, scientists will be able to build — from the bottom up, just as nature does — new and useful structures.

“We have a new set of building blocks,” Mirkin said. “Instead of taking what nature gives you, we can control every property of the new material we make. We’ve always had this vision of building matter and controlling architecture from the bottom up, and now we’ve shown it can be done.”

Using nanoparticles and DNA, Mirkin has built more than 200 different crystal structures with 17 different particle arrangements. Some of the lattice types can be found in nature, but he also has built new structures that have no naturally occurring mineral counterpart.

Mirkin can make new materials and arrangements of particles by controlling the size, shape, type and location of nanoparticles within a given particle lattice. He has developed a set of design rules that allow him to control almost every property of a material.

New materials developed using his method could help improve the efficiency of optics, electronics and energy storage technologies. “These same nanoparticle building blocks have already found wide-spread commercial utility in biology and medicine as diagnostic probes for markers of disease,” Mirkin added.

With this present advance, Mirkin uses nanoparticles as “atoms” and DNA as “bonds.” He starts with a nanoparticle, which could be gold, silver, platinum or a quantum dot, for example. The core material is selected depending on what physical properties the final structure should have.

He then attaches hundreds of strands of DNA (oligonucleotides) to the particle. The oligonucleotide’s DNA sequence and length determine how bonds form between nanoparticles and guide the formation of specific crystal lattices.

“This constitutes a completely new class of building blocks in materials science that gives you a type of programmability that is extraordinarily versatile and powerful,” Mirkin said. “It provides nanotechnologists for the first time the ability to tailor properties of materials in a highly programmable way from the bottom up.”

If I read these two news releases rightly, the process (nanoparticles as atoms and DNA as bonds), Mirkin uses to create new structures is the same process he has used to create spherical nucleic acids. Given Mirkin’s entrepreneurial inclinations, I am curious as to how many and what kind of patents might be ‘protecting’ this work.

Visualizing nanotechnology data with Seed Media Group and GE (General Electric)

Monday, February 11th, 2013

University of Washington (UW) researchers have uploaded a number of nanotechnology infographics on the visualizing.org website, from the UW Division of Design 2010: Nanotechnology Infographics webpage,

There are more than 1/2 dozen of these nanotechnology-themed infographics available on the page. This particular infographic, Nanotechnology:  Size Really is Everything,  has the following credit line,

By Kim Shedrick. Faculty: Karen Cheng, Marco Rolandi. Part of a series of infographics explaining nanotechnology through scale, how it has integrated into society, and what products it is being used in today.

Cheng and Rolandi have been mentioned here before in a Feb. 22, 2012 posting about their University of Washington Design Help Desk and their effort to match up scientists with designers in the interest of producing better science graphics.

I have nothing against better science graphics but I would like to know what information/data is supporting this and their other visualizations. I did resize the graphic to look more closely at the text but there were no references or citations.

Btw, The website handles ‘zooming’ in to see details clumsily. Rather than a click on the zooming tool resulting in a larger image, you are presented with an infographic which is now held within an Adobe PDF reader before you can magnify the image.

For those generally interested in infographics and visualizing date, there’s a lot to choose from on the Visualizing.org website. For those who like to dig a bit deeper, this site is a public relations ploy by General Electric and Seed Media Group. From the About Visualizing.org webpage,

Visualizing.org was created by GE and Seed Media Group to help make data visualization more accessible to the general public; to promote information literacy through the creation, sharing, and discussion of data visualizations; and to provide a unique resource to help simplify complex issues through design.

Seed Media seems to be an outgrowth (pun intended) of SEED Magazine. The magazine, which was founded by Adam Bly when he lived in Montréal, Canada, has always been focused on science and culture.  Headquarters for the magazine were moved to New York and, either at the same time or later, the magazine became a strictly online publication. From the Wikipedia essay (Note: Links have been removed),

Seed (subtitled Science Is Culture; originally Beneath the Surface) is an online science magazine published by Seed Media Group. The magazine looks at big ideas in science, important issues at the intersection of science and society, and the people driving global science culture. Seed was founded in Montreal by Adam Bly and the magazine is now headquartered in New York with bureaus around the world. May/June 2009 (Issue No. 22) was the last print issue. Content continues to be published on the website.

(I first mentioned SEED magazine in a Sept. 18, 2009 posting.) Interestingly, Seed Media which publishes the magazine makes no mention of it (that I could find) on its website. From Seed Media Group’s Learn webpage,

Scientific ThinkingTM

It’s a different way of looking at the world. It’s about using data to uncover patterns and design to confront complexity. It’s about connecting things to reveal systems. It’s about traversing scales and disregarding disciplines, applying neuroscience to economics, math to global health, virology to manufacturing, and genetics to law… It’s about experimenting all the way to understanding. It’s about changing your mind with new evidence – and getting as close to truth as humanly possible.

Getting 7 billion people to think scientifically has never been a small mission. And it has never been more important.

Since 2005, we have offered ideas and stories to help people think scientifically. Now we’re taking the next big step in this journey by creating tools and services to help institutions – companies, governments, and international organizations – do the same. We’re taking our way of seeing and thinking to parliaments, courtrooms, hospitals, construction sites, boardrooms… around the world – to catalyze scientific thinking at scale.

I’m not sure how one would go about trademarking ‘scientific thinking’ as this is  a very commonly used phrase and I’m pretty sure a case could be made that it has been common language for centuries.  This oddity had me going back to the Visualizing.org for their terms and conditions, which are largely unexceptionable,

These are the general terms of use. For terms and conditions regarding the uploading of work, please read the Visualization Submission Agreement.

This Web site is owned by General Electric Company (“GE”) and operated by Seed Media Group, LLC (“Seed”). Throughout the site, the terms “we,” “us” and “our” refer collectively to GE and Seed. We offer this Web site, including all information, tools and services available from this site, to you, the user, conditioned upon your acceptance of all the terms, conditions, policies and notices stated here. Your use of this site constitutes your agreement to these Terms of Use.

When you submit material other than a Visualization, you grant us and our affiliates an unrestricted, nonexclusive, royalty-free, perpetual, irrevocable and fully sublicensable right to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute and display such material throughout the world in any media. You further agree that we are free to use any ideas, concepts, know-how that you or individuals acting on your behalf provide to us. [emphasis mine] You grant us and our affiliates the right to use the name you submit in connection with such material, if we so choose. All personal information provided via this site will be handled in accordance with the site’s online Privacy Policy. You represent and warrant that you own or otherwise control all the rights to the content you post; that the content is accurate; that use of the content you supply does not violate any provision herein and will not cause injury to any person or entity; and that you will indemnify us for all claims resulting from content you supply.

Interesting, non? This has me wondering if it’s possible that  these folks (GE & Seed Media) might decide to use a concept from the visualization without any permission needed. If I understand this rightly, the promise is the visualization won’t be used, all they need is the idea or concept and either company (GE/Seed) or their affiliates can find someone else to illustrate or visualize it.  I find a company (Seed) that’s trying to trademark ‘scientific thinking’ might have some credibility issues regarding their stated terms and conditions for this visualizing.org website.

For the icing on this visualization cake, here’s a video from Visualizing.org’s About page where there is much discussion about the importance of design and visualization of data but not one single scientist is featured,

US Patent and Trademarks Office invests in a public relations campaign

Wednesday, January 23rd, 2013

The Smithsonian Institution in Washington, DC has been renovating its Arts and Industries Building since 2004. It is not scheduled to reopen until 2014 but there will be a ‘soft’ launch of a new partnership between the Smithsonian and the US Patent and Trademark Office (USPTO)  in June 2013, which relates to building’s refurbishment, according to David Bruggeman’s Jan. 20, 2013 posting on his Pasco Phronesis blog,

The partnership will include developing and displaying innovation-themed exhibits in the Arts and Industries Building.  In addition, the Smithsonian and the USPTO will sponsor an Innovation Expo in June 2013 at the USPTO headquarters in Alexandria (with future expos in the Pavilion).  Placing this pavilion in the Arts and Industries Building is a sort-of homecoming, as technology and progress were themes of many exhibits when the building first opened as the National Museum in 1881.

This seven-year, $7.5 million partnership is not the first collaboration between the USPTO and the Smithsonian. …

Here’s more about the Expo from the USPTO Innovation Expo webpage where they are appealing for more exhibitors,

The United States Patent and Trademark Office (USPTO) and the Smithsonian Institution are teaming up to stage the 2013 Innovation Expo. This is your chance to join a select group of technological game-changers in a celebration of ingenuity and patented technology.

The Expo will be held June 20-22, 2013, at the USPTO’s headquarters in Alexandria, Va., just across the Potomac River from the nation’s capital. The combination of the USPTO’s soaring architecture and the Smithsonian’s world-renowned exhibition programing makes the Innovation Expo an extraordinary opportunity for both exhibitors and attendees. Under terms of an agreement signed by the USPTO and the Smithsonian, the Expo will move to the National Mall in the summer of 2014 when the historic Arts and Industries Building reopens.

For three days, exhibits at this free and open-to-the-public event will showcase the latest technological developments from America’s innovators affiliated with large corporations, small businesses, academic institutions, government agencies, and the independent inventor community.

The Expo will also demonstrate the vital role America’s intellectual property system and the USPTO play in promoting and protecting innovation, a role that contributes greatly to America’s competitiveness and prowess in the global economy. [emphases mine]

The application deadline has been extended to March 31, 2013. Exhibition slots will be awarded to qualified U.S. patent owners on a rolling basis. Space is limited, so apply now.

Applications will be reviewed by an independent committee made up of representatives from some of the most important and respected intellectual property organizations.

If that wasn’t enough, the Smithsonian Institution’s Jan. 16, 2013 news release makes the purpose for this project blindingly apparent,

The collaboration will begin this year with an Innovation Expo June 20-22 at the Patent and Trademark Office’s headquarters in Alexandria, Va., where the latest technological developments—patented technologies from American companies—will be showcased. The three-day expo will feature a narrative about how the U.S. patent system promotes innovation and technological development. [emphasis mine] The Innovation Expo, which will be organized in partnership with the Smithsonian, will serve as a template for future expos to be held in the Innovation Pavilion at the A&I Building (the Pavilion will cover around 18,000 square feet of the 40,000 square feet of public space in the building).

During 2013, the Smithsonian will also develop further designs for the new Innovation Pavilion and begin work on plans for exhibitions and programming. The Pavilion will be a center for active learning, engaging visitors using digital technology and informing them about new developments in American innovation and technology. The collaboration is described in a Memorandum of Agreement signed by the Smithsonian Secretary and the director of the U.S. Patent and Trademark Office. The USPTO anticipates supporting the Pavilion over the term of the collaboration.

“The Arts and Industries Building has always been about celebrating innovation and progress, and it has been one of my goals to reopen the building and return it to that purpose,” said Wayne Clough, Smithsonian Secretary. “Through this collaboration with the United States Patent and Trademark Office, we will create a program that not only celebrates American ingenuity, but also reflects the 21st century expectations of our visitors.”

“We look forward to working with the Smithsonian to showcase America’s rich history and bright future of innovation, providing a workshop where inventors of all ages can interact together,” said Under Secretary of Commerce for Intellectual Property and Director of the USPTO David Kappos.

The Smithsonian and the USPTO have worked together on several projects in recent years, including three exhibitions: “The Great American Hall of Wonders” and “To Build a Better Mousetrap” at the Smithsonian American Art Museum, and an exhibition about Apple Inc. founder Steve Jobs’ patents in the Smithsonian’s Ripley Center.

$7.5 million of taxpayer money to promote an intellectual property system that seems to be in serious trouble, along with many other such systems around the world, is a time-honoured fashion of dealing with these kinds of  problems. Generally, they are doomed to fail. As I like to say, you can put a gift bow on a pile of manure but unless you trot a pony out right quickly, it’s no gift. And, the USPTO definitely does not have a pony waiting nearby.

I have written many pieces on the problems with intellectual property systems. There’s this Nov. 23, 2012 posting about patents strangling nanotechnology developments, this Oct. 10, 2012 posting about a UN patent summit concerning smartphones and patent problems; and this June 28, 2012 posting about patent trolls and their impact on the US economy (billions of dollars lost), amongst the others. For more comprehensive news, Techdirt covers the US scene and Michael Geist covers the Canadian scene. Both cover international intellectual property issues as well.

Patent bonanza in nanotechnology (sigh)

Friday, January 4th, 2013

This is more of a snippet than anything else but since it touches on patents and nanotechnology, I’ve decided to post this excerpt (from J. Steven Rutt’s Jan. 2, 2013 posting on JD Supra Law News),

The nanotechnology patent filing boom continues. In 2012, the USPTO [US Patent and Trademark Office] published 4,098 nanotechnology class 977 applications, which represents a 19.2% increase over last year. By way of comparison, in 2008, the USPTO published only 827 nanotechnology applications, and in 2009, only 1,499. Hence, the number has almost tripled in three years.

Rutt is a lawyer with Foley & Lardner LLP and he’s much happier about this news than I am. Of course, a lawyer is much likely to profit from this trend than anyone else (except maybe for a patent troll). My Nov. 23, 2012 posting (Free the nano—stop patenting publicly funded research) highlights some alternative perspectives.

The State of Science and Technology in Canada, 2012 report—examined (part 2: the rest of the report)

Friday, December 28th, 2012

The critiques I offered in relation to the report’s  executive summary (written in early Oct. 2012 but not published ’til now) and other materials can remain more or less intact now that I’ve read the rest of the report (State of Science and Technology in Canada, 2012 [link to full PDF report]). Overall, I think it’s a useful and good report despite what I consider to be some significant shortcomings, not least of which is the uncritical acceptance of the view Canada doesn’t patent enough of its science and its copyright laws are insufficient.

My concern regarding the technometrics (counting patents) is definitely not echoed in the report,

One key weakness of these measures is that not all types of technology development lead to patentable technologies. Some, such as software development, are typically subject to copyright instead. This is particularly relevant for research fields where software development may be a key aspect of developing new technologies such as computer sciences or digital media. Even when patenting is applicable as a means of commercializing and protecting intellectual property (IP), not all inventions are patented. (p. 18 print, p. 42 PDF)

In my view this is a little bit like fussing over the electrical wiring when the foundations of your house are  in such bad repair that the whole structure is in imminent danger of falling. As noted in my critique of the executive summary, the patent system in the US and elsewhere is in deep, deep trouble and, is in fact, hindering innovation. Here’s an interesting comment about patent issues being covered in the media (from a Dec. 27, 2012 posting by Mike Masnick for Techdirt),

There’s been a recent uptick in stories about patent trolling getting mainstream media attention, and the latest example is a recent segment on CBS’s national morning program, CBS This Morning, which explored how patent trolls are hurting the US economy …

… After the segment, done by Jeff Glor, one of the anchors specifically says to him [Austin Meyer of the Laminer company which is fighting a patent troll in court and getting coverage on the morning news]: “So it sounds like this is really stifling innovation and it hurts small businesses!”

Getting back to the report, I’m in more sympathy with the panel’s use of  bibliometrics,

As a mode of research assessment, bibliometric analysis has several important advantages. First, these techniques are built on a well-developed foundation of quantitative data. Publication in peer-reviewed journals is a cornerstone of research dissemination in most scientific and academic disciplines, and bibliometric data are therefore one of the few readily available sources of quantitative information on research activity that allow for comparisons across many fields of research. Second, bibliometric analyses are able to provide information about both research productivity (i.e., the quantity of journal articles produced) and research impact (measured through citations). While there are important methodological issues associated with these metrics (e.g., database coverage by discipline, correct procedures for normalization and aggregation, self-citations, and negative citations, etc.), [emphasis mine] most bibliometric experts agree that, when used appropriately, citation based indicators can be valid measures of the degree to which research has had an impact on later scientific work … (p. 15 print, p. 39, PDF)

Still, I do think that a positive publication bias (i.e., the tendency to publish positive results over negative or inclusive results) in the field medical research should have been mentioned as it is a major area of concern in the use  of bibliometrics and especially since one of the identified areas of  Canadian excellence is  in the field of medical research.

The report’s critique of the opinion surveys has to be the least sophisticated in the entire report,

There are limitations related to the use of opinion surveys generally. The most important of these is simply that their results are, in the end, based entirely on the opinions of those surveyed. (p. 20 print, p. 44 PDF)

Let’s see if I’ve got this right. Counting the number of citations a paper, which was peer-reviewed (i.e., a set of experts were asked for their opinions about the paper prior to publication) and which may have been published due to a positive publication, bias yields data (bibliometrics) which are by definition more reliable than an opinion. In short, the Holy Grail (a sacred object in Christian traditions) is data even though that data or ‘evidence’  is provably based on and biased by opinion which the report writers identify as a limitation. Talk about a conundrum.

Sadly the humanities, arts, and social sciences (but especially humanities and arts) posed quite the problem regarding evidence-based analysis,

While the Panel believes that most other evidence-gathering activities undertaken for this assessment are equally valid across all fields, the limitations of bibliometrics led the Panel to seek measures of the impact of HASS [Humanities, Arts, and Social Sciences] research that would be equivalent to the use of bibliometrics, and would measure knowledge dissemination by books, book chapters, international awards, exhibitions, and other arts productions (e.g., theatre, cinema, etc.). Despite considerable efforts to collect information, however, the Panel found the data to be sparse and methods to collect it unreliable, such that it was not possible to draw conclusions from the resulting data. In short, the available data for HASS-specific outputs did not match the quality and rigour of the other evidence collected for this report. As a result, this evidence was not used in the Panel’s deliberations.

Interestingly, the expert panel was led by Dr. Eliot Phillipson, Sir John and Lady Eaton Professor of Medicine Emeritus, [emphasis mine] University of Toronto, who received his MD in 1963. Evidence-based medicine is the ne plus ultra of medical publishing these days. Is this deep distress over a lack of evidence/data in other fields a reflection of the chair’s biases?  In all the discussion and critique of the methodologies, there was no discussion about reflexivity, i. e., the researcher’s or, in this case, the individual panel members’ (individually or collectively) biases and their possible impact on the report. Even with so called evidence-based medicine, bias and opinion are issues.

While the panel was not tasked to look into business-led R&D efforts (there is a forthcoming assessment focused on that question) mention was made in Chapter 3 (Research Investment) of the report. I was particularly pleased to see mention of the now defunct Nortel with its important century long contribution to Canadian R&D efforts. [Full disclosure: I did contract work for Nortel on and off for two years.]

A closer look at recent R&D expenditure trends shows that Canada’s total investment in R&D has declined in real terms between 2006 and 2010, driven mainly by declining private-sector research performance. Both government and higher education R&D expenditures increased modestly over the same five-year period (growing by 4.5 per cent and 7.1 per cent respectively), while business R&D declined by 17 per cent (see Figure 3.3). Much of this decline can be attributed to the failing fortunes and bankruptcy of Nortel Networks Corporation, which was one of Canada’s top corporate R&D spenders for many years. Between 2008 and 2009 alone, global R&D expenditure at Nortel dropped by 48 per cent, from nearly $1.7 billion to approximately $865 million (Re$earch Infosource, 2010) with significant impact on Canada. Although growth in R&D expenditure at other Canadian companies, particularly Research In Motion, partially compensated for the decline at Nortel, the overall downward trend remains. (p. 30 print, p. 54 PDF)

Chapter 4 of the report (Research Productivity and Impact) is filled with colourful tables and various diagrams and charts illustrating areas of strength and weakness within the Canadian research endeavour, my concerns over the metrics notwithstanding. I was a bit startled by our strength in Philosophy and Theology (Table 4.2 on p. 41 print, p. 65 PDF) as it was not touted in the initial publicity about the report. Of course, they can’t mention everything so there are some other pleasant surprises in here. Going in the other direction, I’m a little disturbed by the drop (down from 1.32 in 1999-2004 to 1.12 in 2005-1010) in the ICT (Information and Communication Technologies) specialization index but that is, as the report notes, a consequence of the Nortel loss and ICT scores better in other measures.

I very much appreciated the inclusion of the questions used in the surveys and the order in which they were asked, a practice which seems to be disappearing elsewhere. The discussion about possible biases and how the data was weighted to account for biases is interesting,

Because the responding population was significantly different than the sample population (p<0.01) for some countries, the data were weighted to correct for over- or under-representation. For example, Canadians accounted for 4.4 per cent of top-cited researchers, but 7.0 per cent of those that responded. After weighting, Canadians account for 4.4 per cent in the analyses that follow. This weighting changed overall results of how many people ranked each country in the top five by less than one per cent.

Even with weighting to remove bias in choice to respond, there could be a perception that self-selection is responsible for some results. Top-cited Canadian researchers in the population sample were not excluded from the survey but the results for Canada cannot be explained by self-promotion since 37 per cent of all respondents identified Canada among the top five countries in their field, but only 7 per cent (4.4 per cent after weighting) of respondents were from Canada. Similarly, 94 per cent of respondents identified the United States as a top country in their field, yet only 33 per cent (41 per cent after weighting) were from the United States. Furthermore, only 9 per cent of respondents had either worked or studied in Canada, and 28 per cent had no personal experience of, or association with, Canada or Canadian researchers (see Table 5.2). It is reasonable to conclude that the vast majority of respondents based their evaluation of Canadian S&T on its scientific contributions and reputation alone. (p. 65 print, p. 89 PDF)

There is another possible bias  not mentioned in the report and that has to do with answering the question: What do you think my strengths and weaknesses are? If somebody asks you that question and you are replying directly, you are likely to focus on their strong points and be as gentle as possible about their weaknesses. Perhaps the panel should consider having another country ask those questions about Canadian research. We might find the conversation becomes a little more forthright and critical.

Chapter 6 of the report discusses research collaboration which is acknowledged as poorly served by bibliometrics. Of course, collaboration is a strategy which Canadians have succeeded with not least because we simply don’t have the resources to go it alone.

One of the features I quite enjoyed in this report are the spotlight features. For example, there’s the one on stem cell research,

Spotlight on Canadian Stem Cell Research

Stem cells were discovered by two Canadian researchers, Dr. James Till and the late Dr. Ernest McCulloch, at the University of Toronto over 50 years ago. This great Canadian contribution to medicine laid the foundation for all stem cell research, and put Canada firmly at the forefront of this field, an international leadership position that is still maintained.

Stem cell research, which is increasingly important to the future of cell replacement therapy for diseased or damaged tissues, spans many disciplines. These disciplines include biology, genetics, bioengineering, social sciences, ethics and law, chemical biology, and bioinformatics. The research aims to understand the mechanisms that govern stem cell behaviour, particularly as it relates to disease development and ultimately treatments or cures.

Stem cell researchers in Canada have a strong history of collaboration that has been supported and strengthened since 2001 by the Stem Cell Network (SCN) (one of the federal Networks of Centres of Excellence), a network considered to be a world leader in the field. Grants awarded through the SCN alone have affected the work of more than 125 principal investigators working in 30 institutions from Halifax to Vancouver. Particularly noteworthy institutions include the Terry Fox Laboratory at the BC Cancer Agency; the Hotchkiss Brain Institute in Calgary; Toronto’s Hospital for Sick Children, Mount Sinai Hospital, University Health Network, and the University of Toronto; the Sprott Centre for Stem Cell Research in Ottawa; and the Institute for Research in Immunology and Cancer in Montréal. In 2010, a new Centre for the Commercialization of Regenerative Medicine was formed to further support stem cell initiatives of interest to industry partners.

Today, Canadian researchers are among the most influential in the stem cell and regenerative medicine field. SCN investigators have published nearly 1,000 papers since 2001 in areas such as cancer stem cells; the endogenous repair of heart, muscle, and neural systems; the expansion of blood stem cells for the treatment of a variety of blood-borne diseases; the development of biomaterials for the delivery and support of cellular structures to replace damaged tissues; the direct conversion of skin stem cells to blood; the evolutionary analysis of leukemia stem cells; the identification of pancreatic stem cells; and the isolation of multipotent blood stem cells capable of forming all cells in the human blood system. (p. 96 print, p. 120 PDF)

Getting back to the report and my concerns, Chapter 8 on S&T capacity focuses on science training and education,

• From 2005 to 2009, there were increases in the number of students graduating from Canadian universities at the college, undergraduate, master’s and doctoral levels, with the largest increase at the doctoral level.

• Canada ranks first in the world for its share of population with post-secondary education.

• International students comprise 11 per cent of doctoral students graduating from Canadian universities. The fields with the largest proportions of international students include Earth and Environmental Sciences; Mathematics and Statistics; Agriculture, Fisheries, and Forestry; and Physics and Astronomy.

• From 1997 to 2010, Canada experienced a positive migration flow of researchers, particularly in the fields of Clinical Medicine, Information and Communication Technologies (ICT), Engineering, and Chemistry. Based on Average Relative Citations, the quality of researchers emigrating and immigrating was comparable.

• In three-quarters of fields, the majority of top-cited researchers surveyed thought Canada has world-leading research infrastructure or programs. (p. 118 print, p. 142 PDF)

Getting back to more critical matters, I don’t see a reference to jobs in this report. It’s all very well to graduate a large number of science PhDs, which we do,  but what’s the point if they can’t find work?

  • From 2005 to 2009, there were increases in the number of students graduating from Canadian universities at the college, undergraduate, master’s and doctoral levels, with the largest increase at the doctoral level.
  • Canada ranks first in the world for its share of population with post-secondary education.
  • International students comprise 11 per cent of doctoral students graduating from Canadian universities. The fields with the largest proportions of international students include Earth and Environmental Sciences; Mathematics and Statistics; Agriculture, Fisheries, and Forestry; and Physics and Astronomy.
  • From 1997 to 2010, Canada experienced a positive migration flow of researchers, particularly in the fields of Clinical Medicine, Information and Communication Technologies (ICT), Engineering, and Chemistry. Based on Average Relative Citations, the quality of researchers emigrating and immigrating was comparable.
  • In three-quarters of fields, the majority of top-cited researchers surveyed thought Canada has world-leading research infrastructure or programs. (p. 118 print, p. 142 PDF)

The Black Whole blog on the University Affairs website has discussed and continues to discuss the dearth of jobs in Canada for science graduates.

Chapter 9 of the report breaks down the information on a regional (provincial) bases. As you might expect, the research powerhouses are Ontario, Québec, Alberta and BC. Chapter 10 summarizes the material on a field basis, i.e., Biology; Chemistry; Agriculture, Fisheries, and Forestry; Econ0mics; Social Sciences; etc.  and those results were widely discussed at the time and are mentioned in part 1 of this commentary.

One of the most striking results in the report is Chapter 11: Conclusions,

The geographic distribution of the six fields of strength is difficult to determine with precision because of the diminished reliability of data below the national level, and the vastly different size of the research enterprise in each province.

The most reliable data that are independent of size are provincial ARC scores. Using this metric, the leading provinces in each field are as follows:

  • Clinical Medicine: Ontario, Quebec, British Columbia, Alberta
  • Historical Studies: New Brunswick, Ontario, British Columbia
  • ICT: British Columbia, Ontario
  •  Physics and Astronomy: British Columbia, Alberta, Ontario, Quebec
  • Psychology and Cognitive Sciences: British Columbia, Nova Scotia, Ontario
  • Visual and Performing Arts: Quebec [emphasis mine] (p. 193 print, p. 217 PDF)

Canada has an international reputation in visual and performing which is driven by one province alone.

As for our national fading reputation in natural resources and environmental S&T that seems predictable by almost any informed observer given funding decisions over the last several years.

The report does identify some emerging strengths,

Although robust methods of identifying emerging areas of S&T are still in their infancy, the Panel used new bibliometric techniques to identify research clusters and their rates of growth. Rapidly emerging research clusters in Canada have keywords relating, most notably, to:

• wireless technologies and networking,

• information processing and computation,

• nanotechnologies and carbon nanotubes, and

• digital media technologies.

The Survey of Canadian S&T Experts pointed to personalized medicine and health care, several energy technologies, tissue engineering, and digital media as areas in which Canada is well placed to become a global leader in development and application. (p. 195 print; p. 219 PDF)

I wish I was better and faster at crunching numbers because I’d like to spend time examining the data more closely but the reality is that all data is imperfect so this report like any snapshot is an approximation. Still, I would have liked to have seen some mention of changing practices in science. For example, there’s the protein-folding game, Foldit, which has attracted over 50,000 players (citizen scientists) who have answered questions and posed possibilities that had not occurred to scientists. Whether this trend will continue to disappear is to be answered in the future. What I find disconcerting is how thoroughly this and other shifting practices (scientists publishing research in blogs) and thorny issues such as the highly problematic patent system were ignored. Individual panel members or the report writers themselves may have wanted to include some mention but we’ll never know because the report is presented as a singular, united authority.

In any event, Bravo! to the expert panel and their support team as this can’t have been an easy job.

If you have anything to say about this commentary or the report please do comment, I would love to hear more opinions.

The State of Science and Technology in Canada, 2012 report—examined (part 1: the executive summary)

Friday, December 28th, 2012

In my Sept. 27, 2012 posting about its launch,  we celebrated the Council of Canadian Academies, The State of science and Technology in Canada, 2012 report unconditionally. Today (Dec. , 2012), it’s time for a closer look.

I’m going to start with the report’s executive summary and some of the background information. Here’s the question the 18-member expert panel attempted to answer,

What is the current state of science and technology in Canada?

Additional direction was provided through two sub-questions:

Considering both basic and applied research fields, what are the scientific disciplines and technological applications in which Canada excels? How are these strengths distributed geographically across the country? How do these trends compare with what has been taking place in comparable countries?

In which scientific disciplines and technological applications has Canada shown the greatest improvement/decline in the last five years? What major trends have emerged? Which scientific disciplines and technological applications have the potential to emerge as areas of prominent strength for Canada?  (p. xi paper, p. 13 PDF)

Here’s more general information about the expert panel,

The Council appointed a multidisciplinary expert panel (the Panel) to address these questions. The Panel’s mandate spanned the full spectrum of fields in engineering, the natural sciences, health sciences, social sciences, the arts, and humanities. It focused primarily on research performed in the higher education sector, as well as the government and not-for-profit sectors. The mandate specifically excluded an examination of S&T performed in the private sector (which is the subject of a separate Council assessment on the state of industrial research and development). The Panel’s report builds upon, updates, and expands the Council’s 2006 report, The State of Science and Technology in Canada. (p. xi paper, p. 13 PDF)

As I noted in my Sept. 27, 2012 posting, the experts have stated,

  • The six research fields in which Canada excels are: clinical medicine, historical studies, information and communication technologies (ICT), physics and astronomy, psychology and cognitive sciences, and visual and performing arts.
  • Canadian science and technology is healthy and growing in both output and impact. With less than 0.5 per cent of the world’s population, Canada produces 4.1 per cent of the world’s research papers and nearly 5 per cent of the world’s most frequently cited papers.
  • In a survey of over 5,000 leading international scientists, Canada’s scientific research enterprise was ranked fourth highest in the world, after the United States, United Kingdom, and Germany.
  • Canada is part of a network of international science and technology collaboration that includes the most scientifically advanced countries in the world. Canada is also attracting high-quality researchers from abroad, such that over the past decade there has been a net migration of researchers into the country.
  • Ontario, Quebec, British Columbia and Alberta are the powerhouses of Canadian science and technology, together accounting for 97 per cent of total Canadian output in terms of research papers. These provinces also have the best performance in patent-related measures and the highest per capita numbers of doctoral students, accounting for more than 90 per cent of doctoral graduates in Canada in 2009.
  • Several fields of specialization were identified in other provinces, such as: agriculture, fisheries, and forestry in Prince Edward Island and Manitoba; historical studies in New Brunswick; biology in Saskatchewan; as well as earth and environmental sciences in Newfoundland and Labrador and Nova Scotia.

The Council did release a backgrounder describing the methodology the experts used to arrive at their conclusions,

In total, the Panel used a number of different methodologies to conduct this assessment, including: bibliometrics (the study of patterns in peer-reviewed journal articles); technometrics (the analysis of patent statistics and indicators), an analysis of highly qualified and skilled personnel; and opinion surveys of Canadian and international experts.

• To draw comparisons among the results derived through the different methodologies, and to integrate the findings, a common classification system was required. The Panel selected a classification system that includes 22 research fields composed of 176 sub-fields, which included fields in the humanities, arts, and social sciences.

Recognizing that some measurement tools used by the Panel (e.g. bibliometric measures) are a less relevant way of measuring science and technology strength in the humanities, arts, and social sciences, where research advances may be less often communicated in peer-reviewed journal articles, the Panel made considerable attempts to evaluate measures such as books and book chapters, exhibitions, and esteem measures such as international awards. However, the Panel was hampered by a lack of available data. As a result, the information and data collected did not meet the Council’s high standards and was excluded from the assessment.

• The Panel determined two measures of quality, a field’s international average relative citations (ARC) rank and its rank in the international survey, to be the most relevant in determining the field’s position compared with other advanced countries. Based on these measures of quality, the

Bibliometric Analysis (the study of patterns in peer-reviewed journal articles)

• Bibliometric analysis has several advantages, namely, that it is built on a well-developed foundation of quantitative data and it is able to provide information on research productivity and impact.

• For this assessment, the Panel relied heavily on bibliometrics to inform their deliberations. The Panel commissioned a comprehensive analysis of Canadian and world publication trends. It included consideration of many different indicators of output and impact, a study of collaboration patterns, and an analysis of researcher migration. Overall, the resulting research was extensive and critical for determining the research fields in which Canada excels.

• Standard bibliometrics do not identify patterns of collaboration among researchers, and may not adequately capture research activity within an interdisciplinary realm. Therefore, the Panel used advanced bibliometric techniques that allow for the identification of patterns of collaboration between Canadian researchers and those in other countries (based on the co-authorship of research papers); and clusters of related research papers, as an alternative approach to assessing Canada’s research strengths.

Technometrics (analysis of patent statistics and indicators)

• Technometrics is an important tool for determining trends in applied research. This type of analysis is routinely used by the Organisation for Economic Co-operation and Development (OECD) and other international organizations in comparing and assessing science and technology outputs across countries.

• In 2006, the Expert Panel on Science and Technology used technometrics to inform their work. In an effort to ensure consistency between the 2006 and the 2012 assessments, technometrics were once again used as a measurement tool.

• The 2012 Panel commissioned a full analysis of Canadian and international patent holdings in the United States Patent and Trademark Office (USPTO) to capture information about Canada’s patent stock and production of intellectual property relative to other advanced economies. Canadians accounted for 18,000 patented inventions in the USPTO, compared to 12,000 at the Canadian Intellectual Property Office during the period 2005-2010.

Opinion Surveys

• To capture a full range of Canadian science and technology activities and strengths, two extensive surveys were commissioned to gather opinions from Canadian experts and from the top one per cent of cited researchers from around the world.

• A survey of Canadian science and technology experts was conducted for the 2006 report. In

2012 this exercise was repeated, however, the survey was modified with three key changes:

o respondents were pre-chosen to ensure those responding were experts in Canadian science and technology;

o to allow comparisons of bibliometric data, the survey was based on the taxonomy of 22 scientific fields and 176 sub-fields; and

o a question regarding the identification of areas of provincial science and technology strength was added.

• To obtain the opinions of international science and technology experts regarding Canada’s science and technology strengths, the Panel conducted a survey of the top cited one percent of international researchers. Over 5,000 responded to the survey, including Canadians. This survey, combined with the results from the bibliometric analysis were used to determine the top six fields of research in which Canada excels.

..

Research Capacity

• The Panel conducted an analysis related to Canadian research capacity. This analysis drew evidence from a variety of sources including bibliometric data and existing information from publications by organizations such as the OECD and Statistics Canada.

• The Panel was also able to look at various Canadian research capacities which included research infrastructure and facilities, trends in Canada’s research faculty and student populations, the degree of collaboration among researchers in Canada and other countries, and researcher migration between Canada and other countries.

To sum it up, they used bibliometrics (how many citations, publications in peer-reviewed journals, etc.), technometrics (the number of patents filed, etc.), and opinion surveys, along with data from other publications. it sounds very impressive but I am wondering why Canada is so often unmentioned as a top research country in analyses produced outside of Canada. In the 2011 OECD (Organization for Economic Cooperation and Development) Science, Technology, and Industry scorecard, we didn’t place all that well according to my Sept. 27, 2011 posting,

Other topics were covered as well, the page hosting the OECD scorecard information boasts a couple of animations, one of particular interest to me (sadly I cannot embed it here). The item of interest is the animation featuring 30 years of R&D investments in OECD and non-OECD countries. It’s a very lively 16 seconds and you may need to view it a few times. You’ll see some countries rocket out of nowhere to make their appearance on the chart (Finland and Korea come to mind) and you’ll see some countries progress steadily while others fall back. The Canadian trajectory shows slow and steady growth until approximately 2000 when we fall back for a year or two after which we remain stagnant. [emphasis added here]

Notably, the 2012 State of Canadian Science and Technology does not mention investment in this sector as they do in the OECD scorecard and  even though that’s usually one of the measures for assessing the health of your science and technology sector.

For reasons that are somewhat of a mystery to me, the report indicates dissatisfaction with Canada’s patent performance (we don’t patent often enough),

In contrast to the nation’s strong performance in knowledge generation is its weaker performance in patents and related measures. Despite producing 4.1 per cent of the world’s scientific papers, Canada holds only 1.7 per cent of world patents, and in 2010 had a negative balance of nearly five billion dollars in royalties and licensing revenues. Despite its low quantity of patents, Canada excels in international comparisons of quality, with citations to patents (ARC scores), ranking second in the world, behind the United States. (p. xiii print, p. 15 PDF)

I have written extensively about the problems with the patent system, especially the system in the US, as per Billions lost to patent trolls; US White House asks for comments on intellectual property (IP) enforcement; and more on IP, in my June 28, 2012 posting and many others. As an indicator or metric for excellence in science and technology, counting your patents (or technometrics as defined by the Council of Canadian Academies) seems problematic. I appreciate this is a standard technique practiced by other countries but couldn’t the panel have expressed some reservations about the practice? Yes, they mention problems with the methodology but they seem unaware that there is growing worldwide dissatisfaction with patent practices.

Thankfully this report is not just a love letter to ourselves. There was an acknowledgement that some areas of excellence have declined since the 2006 report. For those following the Canadian science and technology scene, it can’t be a surprise to see that natural resources and environmental science and technology (S&T) are among the declining areas (not so coincidentally there is less financial investment by the federal government),

This assessment is, in part, an update of the Council’s 2006 assessment of the state of S&T in Canada. Results of the two assessments are not entirely comparable due to methodological differences such as the bibliometric database and classification system used in the two studies, and the survey of top-cited international researchers which was not undertaken in the 2006 assessment. Nevertheless, the Panel concluded that real improvements have occurred in the magnitude and quality of Canadian S&T in several fields including Biology, Clinical Medicine, ICT, Physics and Astronomy, Psychology and Cognitive Sciences, Public Health and Health Services, and Visual and Performing Arts. Two of the four areas identified as strengths in the 2006 report — ICT and health and related life sciences and technologies — have improved by most measures since 2006.

The other two areas identified as strengths in the 2006 report — natural resources and environmental S&T — have not experienced the same improvement as Canadian S&T in general. In the current classification system, these broad areas are now represented mainly by the fields of Agriculture, Fisheries, and Forestry; and Earth and Environmental Sciences. The Panel mapped the current classification system for these fields to the 2006 system and is confident that the overall decline in these fields is real, and not an artefact of different classifications. Scientific output and impact in these fields were either static or declined in 2005–2010 compared to 1994–2004. It should be noted, however, that even though these fields are declining relative to S&T in general, both maintain considerable strength, with Canadian research in Agriculture, Fisheries, and Forestry ranked second in the world in the survey of international researchers, and Earth and Environmental Sciences ranked fourth.

I’m not sure when I’ll get to part 2 of this as I have much on my plate at the moment but I will get back to this.

Cement and concrete festival

Monday, December 24th, 2012

Over the last week or so there’ve been a number of articles and publications about cement and concrete and nanotechnology. The Dec. 17, 2012 Nanowerk Spotlight article by (Mohammed) Shakeel Iqbal and Yashwant Mahajan for India’s Centre for Knowledge Management of Nanoscience & Technology (CKMNT, an ARCI [International Advanced Research Centre for Powder Metallurgy and New Materials] project, Dept.of Science & Technology) seemed to kick off the trend with a patent analysis of nanotechnology-enabled cement innovations,

China is the world leader of patent filings, their 154 patent applications contributing 41% of overall filings, representing the major and active R&D player in the area of nano-based cementitious materials. South Korea is the second leading country with 55 patents (15% of patent filings) on nano-enabled cement, closely followed by United States with 51 patents. Russia, Germany, Japan, France and India are the other leading patent filing countries with 37, 18, 11, 9 and 5 patents respectively, while the remaining patents represent a minor contribution from rest of the world.

….

Dagestan State University (Russia) is the leading assignee with 15-patents to its credit, which are mainly focussed on the development of heat resistant and high compression strength concrete materials. Halliburton Energy Services Inc (USA) comes second with 14-patents that are directed towards well bore cementing for the gas, oil or water wells using nano-cementitious materials.

This is another teaser article from the CKMNT (see my Dec. 13, 2012 posting about their bio-pharmaceutical teaser article) that highlights the findings from a forthcoming report,

A comprehensive Market Research Report on “Nanotechnology in Cement Industry” is proposed to be released by CKMNT in the near future. Interested readers may please contact Dr. Y. R. Mahajan, Technical Adviser and Editor, Nanotech Insights or Mr. H. Purushotham, Team Leader purushotham@ckmnt.com.

Regardless of one’s feelings about patents and patent systems, the article also provides a  good technology overview of the various nanomaterials used as fillers in cement, courtesy of the information in the filed patents.

A December 20, 2012 news item on Azonano points to at least of the reasons cement is occasioning research interest,

Cement production is responsible for 5% of carbon dioxide emissions. If we are to invent a “green” cement, we need to understand in more detail the legendary qualities of traditional Portland cement. A research group partly financed by the Swiss National Science Foundation (SNSF) is tackling this task.

The Dec. 20, 2012 Swiss National Science Foundation (SNSF) news release, which originated the news item on Azonano, goes on to describe the research into exactly how Portland cement’s qualities are derived,

The researchers first developed a packing model of hydrated calcium silicate nanoparticles. They then devised a method for observing their precipitation based on numerical simulations. This approach has proven successful (*). “We were able to show that the different densities on the nano scale can be explained by the packing of nanoparticles of varying sizes. At this crucial level, the result is greater material hardness than if the particles were of the same size and it corresponds to the established knowledge that, at macroscopic level, aggregates of different sizes form a harder concrete.” [said Emanuela Del Gado, SNSF professor at the Institute for Building Materials of the ETH Zurich]

Until today, all attempts to reduce or partially replace burnt calcium carbonate in the production of cement have resulted in less material hardness. By gaining a better understanding of the mechanisms at the nano level, it is possible to identify physical and chemical parameters and to improve the carbon footprint of concrete without reducing its hardness.

For those of a more technical turn of mind, here’s a citation for the paper (from the SNSF press release),

E. Masoero, E. Del Gado, R. J.-M. Pellenq, F.-J. Ulm, and S. Yip (2012). Nanostructure and Nanomechanics of Cement: Polydisperse Colloidal Packing. Physical Review Letters. DOI: 10.1103/PhysRevLett.109.155503

Meanwhile, there’s a technical group in Spain working on ‘biological’ concrete. From the Dec. 20, 2012 news item on ScienceDaily,

In studying this concrete, the researchers at the Structural Technology Group of the Universitat Politècnica de Catalunya • BarcelonaTech (UPC) have focused on two cement-based materials. The first of these is conventional carbonated concrete (based on Portland cement), with which they can obtain a material with a pH of around 8. The second material is manufactured with a magnesium phosphate cement (MPC), a hydraulic conglomerate that does not require any treatment to reduce its pH, since it is slightly acidic.

On account of its quick setting properties, magnesium phosphate cement has been used in the past as a repair material. It has also been employed as a biocement in the field of medicine and dentistry, indicating that it does not have an additional environmental impact.

The innovative feature of this new (vertical multilayer) concrete is that it acts as a natural biological support for the growth and development of certain biological organisms, to be specific, certain families of microalgae, fungi, lichens and mosses.

Here’s a description of the ‘biological’ concrete and its layers,

In order to obtain the biological concrete, besides the pH, other parameters that influence the bioreceptivity of the material have been modified, such as porosity and surface roughness. The result obtained is a multilayer element in the form of a panel which, in addition to a structural layer, consists of three other layers: the first of these is a waterproofing layer situated on top of the structural layer, protecting the latter from possible damage caused by water seeping through.

The next layer is the biological layer, which supports colonisation and allows water to accumulate inside it. It acts as an internal microstructure, aiding retention and expelling moisture; since it has the capacity to capture and store rainwater, this layer facilitates the development of biological organisms.

The final layer is a discontinuous coating layer with a reverse waterproofing function. [emphasis mine] This layer permits the entry of rainwater and prevents it from escaping; in this way, the outflow of water is redirected to where it is aimed to obtain biological growth

This work is designed for a Mediterranean climate and definitely not for rain forests such as the Pacific Northwest which, climatologically, is a temperate rainforest.

The ScienceDaily news item ends with this information about future research and commercialization,

The research has led to a doctoral thesis, which Sandra Manso is writing. At present, the experimental campaign corresponding to the phase of biological growth is being conducted, and this will be completed at the UPC and the University of Ghent (Belgium). This research has received support from Antonio Gómez Bolea, a lecturer in the Faculty of Biology at the University of Barcelona, who has made contributions in the field of biological growth on construction materials.

At present, a patent is in the process of being obtained for this innovative product, and the Catalan company ESCOFET 1886 S.A., a manufacturer of concrete panels for architectural and urban furniture purposes, has already shown an interest in commercialising the material.

Almost at the same time, the US Transport Research Board (a division of the US National Research Council) released this Dec. 19, 2012 announcement about their latest circular,

TRB Transportation Research Circular E-C170: Nanotechnology in Concrete Materials: A Synopsis explore promising new research and innovations using nanotechnology that have the potential to result in improved mechanical properties, volume change properties, durability, and sustainability in concrete materials.

The report is 44 pp (PDF version) and provides an in-depth look (featuring some case studies) at the research not just of nanomaterials but also nanoelectronics and sensors as features in nanotechoology-enabled concrete and cement products.

There you have it, a festival of cement and concrete.