Category Archives: human enhancement

Technology, athletics, and the ‘new’ human

There is a tension between Olympic athletes and Paralympic athletes as it is felt by some able-bodied athletes that paralympic athletes may have an advantage due to their prosthetics. Roger Pielke Jr. has written a fascinating account of the tensions as a means of asking what it all means. From Pielke Jr.’s Aug. 3, 2016 post on the Guardian Science blogs (Note: Links have been removed),

Athletes are humans too, and they sometimes look for a performance improvement through technological enhancements. In my forthcoming book, The Edge: The War Against Cheating and Corruption in the Cutthroat World of Elite Sports, I discuss a range of technological augmentations to both people and to sports, and the challenges that they pose for rule making. In humans, such improvements can be the result of surgery to reshape (like laser eye surgery) or strengthen (such as replacing a ligament with a tendon) the body to aid performance, or to add biological or non-biological parts that the individual wasn’t born with.

One well-known case of technological augmentation involved the South African sprinter Oscar Pistorius, who ran in the 2012 Olympic Games on prosthetic “blades” below his knees (during happier days for the athlete who is currently jailed in South Africa for the killing of his girlfriend, Reeva Steenkamp). Years before the London Games Pistorius began to have success on the track running against able-bodied athletes. As a consequence of this success and Pistorius’s interest in competing at the Olympic games, the International Association of Athletics Federations (or IAAF, which oversees elite track and field competitions) introduced a rule in 2007, focused specifically on Pistorius, prohibiting the “use of any technical device that incorporates springs, wheels, or any other element that provides the user with an advantage over another athlete not using such a device.” Under this rule, Pistorius was determined by the IAAF to be ineligible to compete against able-bodied athletes.

Pistorius appealed the decision to the Court of Arbitration for Sport. The appeal hinged on answering a metaphysical question—how fast would Pistorius have run had he been born with functioning legs below the knee? In other words, did the blades give him an advantage over other athletes that the hypothetical, able-bodied Oscar Pistorius would not have had? Because there never was an able-bodied Pistorius, the CAS looked to scientists to answer the question.

CAS concluded that the IAAF was in fact fixing the rules to prevent Pistorius from competing and that “at least some IAAF officials had determined that they did not want Mr. Pistorius to be acknowledged as eligible to compete in international IAAF-sanctioned events, regardless of the results that properly conducted scientific studies might demonstrate.” CAS determined that it was the responsibility of the IAAF to show “on the balance of probabilities” that Pistorius gained an advantage by running on his blades. CAS concluded that the research commissioned by the IAAF did not show conclusively such an advantage.

As a result, CAS ruled that Pistorius was able to compete in the London Games, where he reached the semifinals of the 400 meters. CAS concluded that resolving such disputes “must be viewed as just one of the challenges of 21st Century life.”

The story does not end with Oscar Pistorius as Pielke, Jr. notes. There has been another challenge, this time by Markus Rehm, a German long-jumper who leaps off a prosthetic leg. Interestingly, the rules have changed since Oscar Pistorius won his case (Note: Links have been removed),

In the Pistorius case, under the rules for inclusion in the Olympic games the burden of proof had been on the IAAF, not the athlete, to demonstrate the presence of an advantage provided by technology.

This precedent was overturned in 2015, when the IAAF quietly introduced a new rule that in such cases reverses the burden of proof. The switch placed the burden of proof on the athlete instead of the governing body. The new rule—which we might call the Rehm Rule, given its timing—states that an athlete with a prosthetic limb (specifically, any “mechanical aid”) cannot participate in IAAF events “unless the athlete can establish on the balance of probabilities that the use of an aid would not provide him with an overall competitive advantage over an athlete not using such aid.” This new rule effectively slammed the door to participation by Paralympians with prosthetics from participating in Olympic Games.
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Even if an athlete might have the resources to enlist researchers to carefully study his or her performance, the IAAF requires the athlete to do something that is very difficult, and often altogether impossible—to prove a negative.

If you have the time, I encourage you to read Pielke Jr.’s piece in its entirety as he notes the secrecy with which the Rehm rule was implemented and the implications for the future. Here’s one last excerpt (Note: A link has been removed),

We may be seeing only the beginning of debates over technological augmentation and sport. Silvia Camporesi, an ethicist at King’s College London, observed: “It is plausible to think that in 50 years, or maybe less, the ‘natural’ able-bodied athletes will just appear anachronistic.” She continues: “As our concept of what is ‘natural’ depends on what we are used to, and evolves with our society and culture, so does our concept of ‘purity’ of sport.”

I have written many times about human augmentation and the possibility that what is now viewed as a ‘normal’ body may one day be viewed as subpar or inferior is not all that farfetched. David Epstein’s 2014 TED talk “Are athletes really getting faster, better, stronger?” points out that in addition to sports technology innovations athletes’ bodies have changed considerably since the beginning of the 20th century. He doesn’t discuss body augmentation but it seems increasingly likely not just for athletes but for everyone.

As for athletes and augmentation, Epstein has an Aug. 7, 2016 Scientific American piece published on Salon.com in time for the 2016 Summer Olympics in Rio de Janeiro,

I knew Eero Mäntyranta had magic blood, but I hadn’t expected to see it in his face. I had tracked him down above the Arctic Circle in Finland where he was — what else? — a reindeer farmer.

He was all red. Not just the crimson sweater with knitted reindeer crossing his belly, but his actual skin. It was cardinal dappled with violet, his nose a bulbous purple plum. In the pictures I’d seen of him in Sports Illustrated in the 1960s — when he’d won three Olympic gold medals in cross-country skiing — he was still white. But now, as an older man, his special blood had turned him red.

Mäntyranta had about 50 percent more red blood cells than a normal man. If Armstrong [Lance Armstrong, cyclist] had as many red blood cells as Mäntyranta, cycling rules would have barred him from even starting a race, unless he could prove it was a natural condition.

During his career, Mäntyranta was accused of doping after his high red blood cell count was discovered. Two decades after he retired, Finnish scientists found his family’s mutation. …

Epstein also covers the Pistorius story, albeit with more detail about the science and controversy of determining whether someone with prosthetics may have an advantage over an able-bodied athlete. Scientists don’t agree about whether or not there is an advantage.

I have many other posts on the topic of augmentation. You can find them under the Human Enhancement category and you can also try the tag, machine/flesh.

Biohackers (also known as bodyhackers or grinders) become more common?

Stephen Melendez’s June 11, 2016 story about biohackers/bodyhackers/grinders for Fast Company sports a striking image in the banner, an x-ray of a pair hands featuring some mysterious additions to the webbing between thumbs and forefingers (Note: Links have been removed),

Tim Shank can guarantee he’ll never leave home without his keys. Why? His house keys are located inside his body.

Shank, the president of the Minneapolis futurist group TwinCities+, has a chip installed in his hand that can communicate electronically with his front door and tell it to unlock itself. His wife has one, too.

In fact, Shank has several chips in his hand, including a near field communication (NFC) chip like the ones used in Apple Pay and similar systems, which stores a virtual business card with contact information for TwinCities+. “[For] people with Android phones, I can just tap their phone with my hand, right over the chip, and it will send that information to their phone,” he says. In the past, he’s also used a chip to store a bitcoin wallet.

Shank is one of a growing number of “biohackers” who implant hardware ranging from microchips to magnets inside their bodies.

Certainly the practice seems considerably more developed since the first time it was mentioned here in a May 27, 2010 posting about a researcher who’d implanted a chip into his body which he then contaminated with a computer virus. In the comments, you’ll find Amal Grafstraa who’s mentioned in the Melendez article at some length, from the Melendez article (Note: Links have been removed),

Some biohackers use their implants in experimental art projects. Others who have disabilities or medical conditions use them to improve their quality of life, while still others use the chips to extend the limits of human perception. …

Experts sometimes caution that the long-term health risks of the practice are still unknown. But many biohackers claim that, if done right, implants can be no more dangerous than getting a piercing or tattoo. In fact, professional body piercers are frequently the ones tasked with installing these implants, given that they possess the training and sterilization equipment necessary to break people’s skin safely.

“When you talk about things like risk, things like putting it in your body, the reality is the risk of having one of these installed is extremely low—it’s even lower than an ear piercing,” claims Amal Graafstra, the founder of Dangerous Things, a biohacking supply company.

Graafstra, who is also the author of the book RFID Toys, says he first had an RFID chip installed in his hand in 2005, which allowed him to unlock doors without a key. When the maker movement took off a few years later, and as more hackers began to explore what they could put inside their bodies, he founded Dangerous Things with the aim of ensuring these procedures were done safely.

“I decided maybe it’s time to wrap a business model around this and make sure that the things people are trying to put in their bodies are safe,” he says. The company works with a network of trained body piercers and offers online manuals and videos for piercers looking to get up to speed on the biohacking movement.

At present, these chips are capable of verifying users’ identities and opening doors. And according to Graafstra, a next-generation chip will have enough on-board cryptographic power to potentially work with credit card terminals securely.

“The technology is there—we can definitely talk to payment terminals with it—but we don’t have the agreements in place with banks [and companies like] MasterCard to make that happen,” he says.

Paying for goods with an implantable chip might sound unusual for consumers and risky for banks, but Graafstra thinks the practice will one day become commonplace. He points to a survey released by Visa last year that found that 25% of Australians are “at least slightly interested” in paying for purchases through a chip implanted in their bodies.

Melendez’s article is fascinating and well worth reading in its entirety. It’s not all keys and commerce as this next and last excerpt shows,

Other implantable technology has more of an aesthetic focus: Pittsburgh biohacking company Grindhouse Wetware offers a below-the-skin, star-shaped array of LED lights called Northstar. While the product was inspired by the on-board lamps of a device called Circadia that Grindhouse founder Tim Cannon implanted to send his body temperature to a smartphone, the commercially available Northstar features only the lights and is designed to resemble natural bioluminescence.

“This particular device is mainly aesthetic,” says Grindhouse spokesman Ryan O’Shea. “It can backlight tattoos or be used in any kind of interpretive dance, or artists can use it in various ways.”

The lights activate in the presence of a magnetic field—one that is often provided by magnets already implanted in the same user’s fingertips. Which brings up another increasingly common piece of bio-hardware: magnetic finger implants. ….

There are other objects that can be implanted in bodies. In one case, an artist, Wafaa Bilal had a camera implanted into the back of his head for a 3rd eye. I mentioned the Iraqi artist in my April 13, 2011 posting titled: Blood, memristors, cyborgs plus brain-controlled computers, prosthetics, and art (scroll down about 75% of the way). Bilal was unable to find a doctor who would perform the procedure so he went to a body-piercing studio. Unfortunately, the posting chronicles his infection and subsequent removal of the camera (h/t Feb. 11, 2011 BBC [British Broadcasting Corporation] news online article).

Observations

It’s been a while since I’ve written about bodyhacking and I’d almost forgotten about the practice relegating it to the category of “one of those trendy ideas that get left behind as interest shifts.” My own interest had shifted more firmly to neuroprosthetics (the integration of prostheses into the nervous system).

I had coined a tag for bodyhacking and neuroprostheses: machine/flesh which covers both those topics and more (e.g. cyborgs) as we continue to integrate machines into our bodies.

Final note

I was reminded of Wafaa Bilal recently when checking out a local arts magazine, Preview: the gallery guide, June/July/August 2016 issue. His work (the 168:01show) is being shown in Calgary, Alberta, Canada at the Esker Foundation from May 27 to August 28, 2016,

168:01 is a major solo exhibition of new and recent work by Iraqi-born, New York-based artist Wafaa Bilal, renowned for his online performances and technologically driven encounters that speak to the impact of international politics on individual lives.

In 168:01, Bilal takes the Bayt al-Hikma, or House of Wisdom, as a starting point for a sculptural installation of a library. The Bayt al-Hikma was a major academic center during the Islamic Golden Age where Muslim, Jewish, and Christian scholars studied the humanities and science. By the middle of the Ninth Century, the House of Wisdom had accumulated the largest library in the world. Four centuries later, a Mongol siege laid waste to all the libraries of Baghdad along with the House of Wisdom. According to some accounts, the library was thrown into the Tigris River to create a bridge of books for the Mongol army to cross. The pages bled ink into the river for seven days – or 168 hours, after which the books were drained of knowledge. Today, the Bayt al-Hikma represents one of the most well-known examples of historic cultural loss as a casualty of wartime.

For this exhibition, Bilal has constructed a makeshift library filled with empty white books. The white books symbolize the priceless cultural heritage destroyed at Bayt al-Hikma as well as the libraries, archives, and museums whose systematic decimation by occupying forces continues to ravage his homeland. Throughout the duration of the exhibition, the white books will slowly be replaced with visitor donations from a wishlist compiled by The College of Fine Arts at the University of Baghdad, whose library was looted and destroyed in 2003. At the end of each week a volunteer unpacks the accumulated shipments, catalogues each new book by hand, and places the books on the shelves. At the end of the exhibition, all the donated books will be sent to the University of Baghdad to help rebuild their library. This exchange symbolizes the power of individuals to rectify violence inflicted on cultural spaces that are meant to preserve and store knowledge for future generations.

In conjunction with the library, Bilal presents a powerful suite of photographs titled The Ashes Series that brings the viewer closer to images of violence and war in the Middle East. In an effort to foster empathy and humanize the onslaught of violent images that inundate Western media during wartime, Bilal has reconstructed journalistic images of the destruction caused by the Iraq War. He writes, “Reconstructing the destructed spaces is a way to exist in them, to share them with an audience, and to provide a layer of distance, as the original photographs are too violent and run the risk of alienating the viewer. It represents an attempt to make sense of the destruction and to preserve the moment of serenity after the dust has settled, to give the ephemeral moment extended life in a mix of beauty and violence.” In the photograph Al-Mutanabbi Street from The Ashes Series, the viewer encounters dilapidated historic and modern buildings on a street covered with layers upon layers of rubble and fragments of torn books. Bilal’s images emanate a slowness that deepens engagement between the viewer and the image, thereby inviting them to share the burden of obliterated societies and reimagine a world built on the values of peace and hope.

The House of Wisdom has been mentioned here a few times perhaps most comprehensively and in the context of the then recent opening of the King Abdullah University for Science and Technology (KAUST; located in Saudi Arabia) in this Sept. 24, 2009 posting (scroll down about 45% of the way).

Anyone interested in hacking their own body?

 

I expect you can find out more Amal Grafstraa’s website.

Exploring the science of Iron Man (prior to the opening of Captain America: Civil War, aka, Captain America vs. Iron Man)

Not unexpectedly, there’s a news item about science and Iron Man (it’s getting quite common for the science in movies to be promoted and discussed) just a few weeks before the movie Captain America: Civil War or, as it’s also known, Captain America vs. Iron Man opens in the US. From an April 26, 2016 news item on phys.org,

… how much of our favourite superheros’ power lies in science and how much is complete fiction?

As Iron Man’s name suggests, he wears a suit of “iron” which gives him his abilities—superhuman strength, flight and an arsenal of weapons—and protects him from harm.

In scientific parlance, the Iron man suit is an exoskeleton which is worn outside the body to enhance it.

An April 26, 2016 posting by Chris Marr on the ScienceNetwork Western Australia blog, which originated the news item, provides an interesting overview of exoskeletons and some of the scientific obstacles still to be overcome before they become commonplace,

In the 1960s, the first real powered exoskeleton appeared—a machine integrated with the human frame and movements which provided the wearer with 25 times his natural lifting capacity.

The major drawback then was that the unit itself weighed in at 680kg.

UWA [University of Western Australia] Professor Adrian Keating suggests that some of the technology seen in the latest Marvel blockbuster, such as controlling the exoskeleton with simple thoughts, will be available in the near future by leveraging ongoing advances of multi-disciplinary research teams.

“Dust grain-sized micromachines could be programmed to cooperate to form reconfigurable materials such as the retractable face mask, for example,” Prof Keating says.

However, all of these devices are in need of a power unit small enough to be carried yet providing enough capacity for more than a few minutes of superhuman use, he says.

Does anyone have a spare Arc Reactor?

Currently, most exoskeleton development has been for medical applications, with devices designed to give mobility to amputees and paraplegics, and there are a number in commercial production and use.

Dr Lei Cui, who lectures in Mechatronics at Curtin University, has recently developed both a hand and leg exoskeleton, designed for use by patients who have undergone surgery or have nerve dysfunction, spinal injuries or muscular dysfunction.

“Currently we use an internal battery that lasts about two hours in the glove, which can be programmed for only four different movement patterns,” Dr Cui says.

Dr Cui’s exoskeletons are made from plastic, making them light but offering little protection compared to the titanium exterior of Stark’s favourite suit.

It’s clear that we are a long way from being able to produce a working Iron Man suit at all, let alone one that flies, protects the wearer and has the capacity to fight back.

This is not the first time I’ve featured a science and pop culture story here. You can check out my April 28, 2014 posting for a story about how Captain America’s shield could be a supercapacitor (it also has a link to a North Carolina State University blog featuring science and other comic book heroes) and there is my May 6, 2013 post about Iron Man 3 and a real life injectable nano-network.

As for ScienceNetwork Western Australia, here’s more from their About SWNA page,

ScienceNetwork Western Australia (SNWA) is an online science news service devoted to sharing WA’s achievements in science and technology.

SNWA is produced by Scitech, the state’s science and technology centre and supported by the WA Government’s Office of Science via the Department of the Premier and Cabinet.

Our team of freelance writers work with in-house editors based at Scitech to bring you news from all fields of science, and from the research, government and private industry sectors working throughout the state. Our writers also produce profile stories on scientists. We collaborate with leading WA institutions to bring you Perspectives from prominent WA scientists and opinion leaders.

We also share news of science-related events and information about the greater WA science community including WA’s Chief Scientist, the Premier’s Science Awards, Innovator of the Year Awards and information on regional community science engagement.

Since our commencement in 2003 we have grown to share WA’s stories with local, national and global audiences. Our articles are regularly republished in print and online media in the metropolitan and regional areas.

Bravo to the Western Australia government! I wish there  initiatives of this type in Canada, the closest we have is the French language Agence Science-Presse supported by the Province of Québec.

Chip in brain lets quadriplegic (tetraplegic) move hands and fingers

An April 13, 2016 news item on ScienceDaily describes the latest brain implant,

Six years ago, he was paralyzed in a diving accident. Today, he participates in clinical sessions during which he can grasp and swipe a credit card or play a guitar video game with his own fingers and hand. These complex functional movements are driven by his own thoughts and a prototype medical system that are detailed in a study published online today in the journal Nature.

The device, called NeuroLife, was invented at Battelle, which teamed with physicians and neuroscientists from The Ohio State University Wexner Medical Center to develop the research approach and perform the clinical study. Ohio State doctors identified the study participant and implanted a tiny computer chip into his brain.

An April 13, 2016 Ohio State University news release on EurekAlert, which originated the news item, provides more details about the participant and the technology,

That pioneering participant, Ian Burkhart, is a 24-year-old quadriplegic from Dublin, Ohio, and the first person to use this technology. This electronic neural bypass for spinal cord injuries reconnects the brain directly to muscles, allowing voluntary and functional control of a paralyzed limb by using his thoughts. The device interprets thoughts and brain signals then bypasses his injured spinal cord and connects directly to a sleeve that stimulates the muscles that control his arm and hand.

“We’re showing for the first time that a quadriplegic patient is able to improve his level of motor function and hand movements,” said Dr. Ali Rezai, a co-author of the study and a neurosurgeon at Ohio State’s Wexner Medical Center.

Burkhart first demonstrated the neural bypass technology in June 2014, when he was able to open and close his hand simply by thinking about it. Now, he can perform more sophisticated movements with his hands and fingers such as picking up a spoon or picking up and holding a phone to his ear — things he couldn’t do before and which can significantly improve his quality of life.

“It’s amazing to see what he’s accomplished,” said Nick Annetta, electrical engineering lead for Battelle’s team on the project. “Ian can grasp a bottle, pour the contents of the bottle into a jar and put the bottle back down. Then he takes a stir bar, grips that and then stirs the contents of the jar that he just poured and puts it back down. He’s controlling it every step of the way.”

The neural bypass technology combines algorithms that learn and decode the user’s brain activity and a high-definition muscle stimulation sleeve that translates neural impulses from the brain and transmits new signals to the paralyzed limb.

The Battelle team has been working on this technology for more than a decade. To develop the algorithms, software and stimulation sleeve, Battelle scientists first recorded neural impulses from an electrode array implanted in a paralyzed person’s brain. They used that recorded data to illustrate the device’s effect on the patient and prove the concept.

Four years ago, former Battelle researcher Chad Bouton and his team began collaborating with Ohio State Neurological Institute researchers and clinicians Rezai and Dr. Jerry Mysiw to design the clinical trials and validate the feasibility of using the neural bypass technology in patients.

“In the 30 years I’ve been in this field, this is the first time we’ve been able to offer realistic hope to people who have very challenging lives,” said Mysiw, chair of the Department of Physical Medicine and Rehabilitation at Ohio State. “What we’re looking to do is help these people regain more control over their bodies.”

During a three-hour surgery in April 2014, Rezai implanted a computer chip smaller than a pea onto the motor cortex of Burkhart’s brain.

The Ohio State and Battelle teams worked together to figure out the correct sequence of electrodes to stimulate to allow Burkhart to move his fingers and hand functionally. For example, Burkhart uses different brain signals and muscles to rotate his hand, make a fist or pinch his fingers together to grasp an object. As part of the study, Burkhart worked for months using the electrode sleeve to stimulate his forearm to rebuild his atrophied muscles so they would be more responsive to the electric stimulation.

“During the last decade, we’ve learned how to decipher brain signals in patients who are completely paralyzed and now, for the first time, those thoughts are being turned into movement,” said study co-author Bouton, who directed Battelle’s team before he joined the New York-based Feinstein Institute for Medical Research. “Our findings show that signals recorded from within the brain can be re-routed around an injury to the spinal cord, allowing restoration of functional movement and even movement of individual fingers.”

Burkhart said it was an easy decision to participate in the FDA-approved clinical trial at Ohio State’s Wexner Medical Center because he wanted to try to help others with spinal cord injuries. “I just kind of think that it’s my obligation to society,” Burkhart said. “If someone else had an opportunity to do it in some other part of the world, I would hope that they would commit their time so that everyone can benefit from it in the future.”

Rezai and the team from Battelle agree that this technology holds the promise to help patients affected by various brain and spinal cord injuries such as strokes and traumatic brain injury to be more independent and functional.

“We’re hoping that this technology will evolve into a wireless system connecting brain signals and thoughts to the outside world to improve the function and quality of life for those with disabilities,” Rezai said. “One of our major goals is to make this readily available to be used by patients at home.”

Burkhart is the first of a potential five participants in a clinical study. Mysiw and Rezai have identified a second patient who is scheduled to start the study in the summer.

“Participating in this research has changed me in the sense that I have a lot more hope for the future now,” Burkhart said. “I always did have a certain level of hope, but now I know, first-hand, that there are going to be improvements in science and technology that will make my life better.”

Here’s a link to and a citation for the paper,

Restoring cortical control of functional movement in a human with quadriplegia by Chad E. Bouton, Ammar Shaikhouni, Nicholas V. Annetta, Marcia A. Bockbrader, David A. Friedenberg, Dylan M. Nielson, Gaurav Sharma, Per B. Sederberg, Bradley C. Glenn, W. Jerry Mysiw, Austin G. Morgan, Milind Deogaonkar, & Ali R. Rezai. Nature (2016)  doi:10.1038/nature17435 Published online 13 April 2016

This paper is behind a paywall but there is an in depth April 13, 2016 article by Linda Geddes in Nature providing nuggets of new insight such as this,

Previous studies have suggested that after spinal-cord injuries, the brain undergoes ‘reorganization’ — a rewiring of its connections. But this new work suggests that the degree of reorganization occurring after such injuries may be less than previously assumed. “It gives us a lot of hope that there are perhaps not as many neural changes in the brain as we might have imagined [emphasis mine] after an injury like this, and we can bypass damaged areas of the spinal cord to regain movement,” says Bouton.

The Geddes article is open access.

Finally, there’s an April 13, 2016 article by Will Oremus for Slate.com, which notes that this story is not a fairy tale as there’s a possibility the chip will be removed in the near future as the US Food and Drug Administration’s approval of the device was conditional due to this,

Burkhart knows the device was never meant to last forever. The brain implant’s efficacy gradually degrades over time due to scarring in the brain tissue, and eventually that hardware degradation will start to undo the progress that Burkhart and the software have made together.

He told me he has accepted that his newfound mobility is temporary, and that the progress he has made is likely to benefit posterity more than it benefits him. “I now know that when I’m connected to the system I can do all these great things. It won’t be too much of a shock to me [when it’s over], because even now I can only use the system for a few hours a week when I’m down in the lab. But it will be something I’ll certainly miss.”

10- to 15-year-olds as superhero cyborgs

It’s not the first time someone’s tried to redesign a prosthetic (an Aug. 7, 2009 posting touched on reimagining prosthetic arms and other topics) but it’s the first project I’ve seen where children are the featured designers. A Jan. 27, 2016 article by Emily Price for The Guardian describes the idea,

In a hidden room in the back of a pier overlooking the San Francisco Bay, a young girl shoots glitter across the room with a flick of her wrist. On the other side of the room, a boy is shooting darts from his wrist – some travelling at least 20ft high, onto a landing above. It feels like a superhero training center or a party for the next generation of X-Men and, in a way, it is.

This is Superhero Cyborgs, an event that brings six children together with 3D design specialists and augmentation experts to create unique prosthetics that will turn each child into a kind of superhero.

The children are aged between 10 and 15 and all have upper-limb differences, having either been born without a hand or having lost a limb. They are spending five days with prosthetics experts and a design team from 3D software firm Autodesk, creating prosthetics that turn a replacement hand into something much more special.

“We started asking: ‘Why are we trying to replicate the functionality of a hand?’ when we could really do anything. Things that are way cooler that hands aren’t able to do,” says Kate Ganim, co-founder and co-director at KidMob, the nonprofit group that organised this project in partnership with San Rafael, California 3D software firm Autodesk. KidMob first ran this type of project at Rhode Island’s Brown University in 2014.

Details of each superhero prosthetic are being posted on the DIY site Instructables and hacking site Project Ignite in the hope that it inspires other groups, schools and individuals to follow suit. “A classroom might work on building a project and then donate a finished hand to someone they know or appoint it to someone in the community who is in need,” O’Rourke said.

I searched the Project Ignite website using the term ‘superhero cyborg’ and did not receive a single hit. I also used the search term on the Instructables website and got many hits but did not see one that resembled any of the project descriptions in Price’s article. Unfortunately, Price did not offer any suggestions for search terms.

Getting back to the project, Jessica Hullinger has written a March 28, 2016 article about Superhero Cyborgs for Fast Company where she follows one of the participants (Note: Links have been removed),

Jordan [Jordan Reeves, a 10-year-old from Columbia, Missouri] was born with a limb difference: her left arm stops just above the elbow. When she found out she was headed to the Superhero Cyborg workshop, she was over the moon. “I was like, ‘Wow, I can’t believe I’m actually doing this,'” she says.

Over the course of five days, she and five other kids between the ages of 10 and 15 worked with design experts and engineers from Autodesk to brainstorm ideas. “Basically, if they could design the prosthetic or body modification of their dreams in a superhero context, what would that look like?” asks Sarah O’Rourke, a senior product marketing manager with Autodesk.

For Jordan, it looks very sparkly. Her plan was to transform her arm into a cannon that spread a delightful cloud of glitter wherever she went. She started with a few sketches. Then she created a 3-D-printed cast of her arm and a plastic cuff made to fit over it, for prototyping purposes. The kids used Autodesk’s 3-D design tools like TinkerCAD and Fusion 360 to test their prototypes. …

“For us, our interest is in getting kids familiar with taking an idea from concept to execution and learning the skills along the way to do that,” says Ganim. “Ideally, it’s not about the end product they end up with out of workshop; it’s more about realizing they’re not just subject to what’s available on the market. It creates this interesting closed loop system where they’re both designer and end user. That is very powerful.”

The workshop is over now but the children will continue for a few months working on their designs and, in some cases, creating prostheses that can have practical applications.

You can find out more about Superhero Cyborgs in a Feb. 7, 2016 posting on the KIDmob website blog,

SuperHeroCyborgSydney
Sydney: A dual water gun shooter that will automatically refill itself

I got more information on KIDmob on the About page,

KIDmob is the mobile, kid-integrated design firm. We are a Bay Area fiscally sponsored not-for-profit organization that believes design education is an opportunity for creative engagement and community empowerment. We take our passion on the road to bring our innovative approach to local communities around the world.

We engage in the design process through project-based learning. KIDmob workshops use the design process as a beginning curriculum framework on which to build a customized local project brief, based on a partner-identified need. Our workshops facilitate partners in devising imaginative solutions for their community, by their community. We strive to foster local stewardship within all of our projects.

We promote an energetic, hands-on approach to learning – our workshops create an immersive environment of moving, shaking, sketching, whirling, splatting, slicing, sawing, jitterbugging creativity. When we are not swimming in post-it notes, we like to explore all kinds of technologies, from pencils to circuitry mills, as tools for creative expression.

Feeling with a bionic finger

From what I understand one of the most difficult aspects of an amputation is the loss of touch, so, bravo to the engineers. From a March 8, 2016 news item on ScienceDaily,

An amputee was able to feel smoothness and roughness in real-time with an artificial fingertip that was surgically connected to nerves in his upper arm. Moreover, the nerves of non-amputees can also be stimulated to feel roughness, without the need of surgery, meaning that prosthetic touch for amputees can now be developed and safely tested on intact individuals.

The technology to deliver this sophisticated tactile information was developed by Silvestro Micera and his team at EPFL (Ecole polytechnique fédérale de Lausanne) and SSSA (Scuola Superiore Sant’Anna) together with Calogero Oddo and his team at SSSA. The results, published today in eLife, provide new and accelerated avenues for developing bionic prostheses, enhanced with sensory feedback.

A March 8, 2016 EPFL press release (also on EurekAlert), which originated the news item, provides more information about Sorenson’s experience and about the other tests the research team performed,

“The stimulation felt almost like what I would feel with my hand,” says amputee Dennis Aabo Sørensen about the artificial fingertip connected to his stump. He continues, “I still feel my missing hand, it is always clenched in a fist. I felt the texture sensations at the tip of the index finger of my phantom hand.”

Sørensen is the first person in the world to recognize texture using a bionic fingertip connected to electrodes that were surgically implanted above his stump.

Nerves in Sørensen’s arm were wired to an artificial fingertip equipped with sensors. A machine controlled the movement of the fingertip over different pieces of plastic engraved with different patterns, smooth or rough. As the fingertip moved across the textured plastic, the sensors generated an electrical signal. This signal was translated into a series of electrical spikes, imitating the language of the nervous system, then delivered to the nerves.

Sørensen could distinguish between rough and smooth surfaces 96% of the time.

In a previous study, Sorensen’s implants were connected to a sensory-enhanced prosthetic hand that allowed him to recognize shape and softness. In this new publication about texture in the journal eLife, the bionic fingertip attains a superior level of touch resolution.

Simulating touch in non-amputees

This same experiment testing coarseness was performed on non-amputees, without the need of surgery. The tactile information was delivered through fine, needles that were temporarily attached to the arm’s median nerve through the skin. The non-amputees were able to distinguish roughness in textures 77% of the time.

But does this information about touch from the bionic fingertip really resemble the feeling of touch from a real finger? The scientists tested this by comparing brain-wave activity of the non-amputees, once with the artificial fingertip and then with their own finger. The brain scans collected by an EEG cap on the subject’s head revealed that activated regions in the brain were analogous.

The research demonstrates that the needles relay the information about texture in much the same way as the implanted electrodes, giving scientists new protocols to accelerate for improving touch resolution in prosthetics.

“This study merges fundamental sciences and applied engineering: it provides additional evidence that research in neuroprosthetics can contribute to the neuroscience debate, specifically about the neuronal mechanisms of the human sense of touch,” says Calogero Oddo of the BioRobotics Institute of SSSA. “It will also be translated to other applications such as artificial touch in robotics for surgery, rescue, and manufacturing.”

Here’s a link to and a citation for the paper,

Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans by Calogero Maria Oddo, Stanisa Raspopovic, Fiorenzo Artoni, Alberto Mazzoni, Giacomo Spigler, Francesco Petrini, Federica Giambattistelli, Fabrizio Vecchio, Francesca Miraglia, Loredana Zollo, Giovanni Di Pino, Domenico Camboni, Maria Chiara Carrozza, Eugenio Guglielmelli, Paolo Maria Rossini, Ugo Faraguna, Silvestro Micera. eLife, 2016; 5 DOI: 10.7554/eLife.09148 Published March 8, 2016

This paper appears to be open access.

Feasibility of printing ear, bone, and muscle structures

Over ten years ago I attended a show at the Vancouver (Canada) Art Gallery titled ‘Massive Change’ where I saw part of a nose or ear being grown in a petri dish (the work was from an Israeli laboratory) and that was my introduction to tissue engineering. For anyone who’s been following the tissue engineering story, 3D printers have sped up the growth process considerably. More recently, researchers at Wake Forest Baptist Medical Center (North Carolina, US) have announced another step forward for growing organs and body parts, from a Feb. 15, 2016 Wake Forest Baptist Medical Center news release on EurekAlert,

Using a sophisticated, custom-designed 3D printer, regenerative medicine scientists at Wake Forest Baptist Medical Center have proved that it is feasible to print living tissue structures to replace injured or diseased tissue in patients.

Reporting in Nature Biotechnology, the scientists said they printed ear, bone and muscle structures. When implanted in animals, the structures matured into functional tissue and developed a system of blood vessels. Most importantly, these early results indicate that the structures have the right size, strength and function for use in humans.

“This novel tissue and organ printer is an important advance in our quest to make replacement tissue for patients,” said Anthony Atala, M.D., director of the Wake Forest Institute for Regenerative Medicine (WFIRM) and senior author on the study. “It can fabricate stable, human-scale tissue of any shape. With further development, this technology could potentially be used to print living tissue and organ structures for surgical implantation.”

With funding from the Armed Forces Institute of Regenerative Medicine, a federally funded effort to apply regenerative medicine to battlefield injuries, Atala’s team aims to implant bioprinted muscle, cartilage and bone in patients in the future.

Tissue engineering is a science that aims to grow replacement tissues and organs in the laboratory to help solve the shortage of donated tissue available for transplants. The precision of 3D printing makes it a promising method for replicating the body’s complex tissues and organs. However, current printers based on jetting, extrusion and laser-induced forward transfer cannot produce structures with sufficient size or strength to implant in the body.

The Integrated Tissue and Organ Printing System (ITOP), developed over a 10-year period by scientists at the Institute for Regenerative Medicine, overcomes these challenges. The system deposits both bio-degradable, plastic-like materials to form the tissue “shape” and water-based gels that contain the cells. In addition, a strong, temporary outer structure is formed. The printing process does not harm the cells.

A major challenge of tissue engineering is ensuring that implanted structures live long enough to integrate with the body. The Wake Forest Baptist scientists addressed this in two ways. They optimized the water-based “ink” that holds the cells so that it promotes cell health and growth and they printed a lattice of micro-channels throughout the structures. These channels allow nutrients and oxygen from the body to diffuse into the structures and keep them live while they develop a system of blood vessels.

It has been previously shown that tissue structures without ready-made blood vessels must be smaller than 200 microns (0.007 inches) for cells to survive. In these studies, a baby-sized ear structure (1.5 inches) survived and showed signs of vascularization at one and two months after implantation.

“Our results indicate that the bio-ink combination we used, combined with the micro-channels, provides the right environment to keep the cells alive and to support cell and tissue growth,” said Atala.

Another advantage of the ITOP system is its ability to use data from CT and MRI scans to “tailor-make” tissue for patients. For a patient missing an ear, for example, the system could print a matching structure.

Several proof-of-concept experiments demonstrated the capabilities of ITOP. To show that ITOP can generate complex 3D structures, printed, human-sized external ears were implanted under the skin of mice. Two months later, the shape of the implanted ear was well-maintained and cartilage tissue and blood vessels had formed.

To demonstrate the ITOP can generate organized soft tissue structures, printed muscle tissue was implanted in rats. After two weeks, tests confirmed that the muscle was robust enough to maintain its structural characteristics, become vascularized and induce nerve formation.

And, to show that construction of a human-sized bone structure, jaw bone fragments were printed using human stem cells. The fragments were the size and shape needed for facial reconstruction in humans. To study the maturation of bioprinted bone in the body, printed segments of skull bone were implanted in rats. After five months, the bioprinted structures had formed vascularized bone tissue.

Ongoing studies will measure longer-term outcomes.

###

The research was supported, in part, by grants from the Armed Forces Institute of Regenerative Medicine (W81XWH-08-2-0032), the Telemedicine and Advanced Technology Research Center at the U.S. Army Medical Research and Material Command (W81XWH-07-1-0718) and the Defense Threat Reduction Agency (N66001-13-C-2027).

(Sometimes the information about the funding agencies is almost as interesting as the research.) Here’s a link to and a citation for the paper,

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity by Hyun-Wook Kang, Sang Jin Lee, In Kap Ko, Carlos Kengla, James J Yoo, & Anthony Atala. Nature Biotechnology (2016)  doi:10.1038/nbt.3413 Published online 15 February 2016

This paper is behind a paywall.

As you can see, despite being printed, this latest ear is also spending time in a dish,

WakeBaptistEar

Courtesy: Wake Forest Baptist Medical Center

Sinagpore’s new chip could make low-powered wireless neural implants a possibility and Australians develop their own neural implant

Singapore

This research from Singapore could make neuroprosthetics and exoskeletons a little easier to manage as long as you don’t mind having a neural implant. From a Feb. 11, 2016 news item on ScienceDaily,

A versatile chip offers multiple applications in various electronic devices, report researchers, suggested that there is now hope that a low-powered, wireless neural implant may soon be a reality. Neural implants when embedded in the brain can alleviate the debilitating symptoms of Parkinson’s disease or give paraplegic people the ability to move their prosthetic limbs.

Caption: NTU Asst Prof Arindam Basu is holding his low-powered smart chip. Credit: NTU Singapore

Caption: NTU Asst Prof Arindam Basu is holding his low-powered smart chip. Credit: NTU Singapore

A Feb. 11, 2016 Nanyang Technological University (NTU) press release (also on EurekAlert), which originated the news item, provides more detail,

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a small smart chip that can be paired with neural implants for efficient wireless transmission of brain signals.

Neural implants when embedded in the brain can alleviate the debilitating symptoms of Parkinson’s disease or give paraplegic people the ability to move their prosthetic limbs.

However, they need to be connected by wires to an external device outside the body. For a prosthetic patient, the neural implant is connected to a computer that decodes the brain signals so the artificial limb can move.

These external wires are not only cumbersome but the permanent openings which allow the wires into the brain increases the risk of infections.

The new chip by NTU scientists can allow the transmission of brain data wirelessly and with high accuracy.

Assistant Professor Arindam Basu from NTU’s School of Electrical and Electronic Engineering said the research team have tested the chip on data recorded from animal models, which showed that it could decode the brain’s signal to the hand and fingers with 95 per cent accuracy.

“What we have developed is a very versatile smart chip that can process data, analyse patterns and spot the difference,” explained Prof Basu.

“It is about a hundred times more efficient than current processing chips on the market. It will lead to more compact medical wearable devices, such as portable ECG monitoring devices and neural implants, since we no longer need large batteries to power them.”

Different from other wireless implants

To achieve high accuracy in decoding brain signals, implants require thousands of channels of raw data. To wirelessly transmit this large amount of data, more power is also needed which means either bigger batteries or more frequent recharging.

This is not feasible as there is limited space in the brain for implants while frequent recharging means the implants cannot be used for long-term recording of signals.

Current wireless implant prototypes thus suffer from a lack of accuracy as they lack the bandwidth to send out thousands of channels of raw data.

Instead of enlarging the power source to support the transmission of raw data, Asst Prof Basu tried to reduce the amount of data that needs to be transmitted.

Designed to be extremely power-efficient, NTU’s patented smart chip will analyse and decode the thousands of signals from the neural implants in the brain, before compressing the results and sending it wirelessly to a small external receiver.

This invention and its findings were published last month [December 2015] in the prestigious journal, IEEE Transactions on Biomedical Circuits & Systems, by the Institute of Electrical and Electronics Engineers, the world’s largest professional association for the advancement of technology.

Its underlying science was also featured in three international engineering conferences (two in Atlanta, USA and one in China) over the last three months.

Versatile smart chip with multiple uses

This new smart chip is designed to analyse data patterns and spot any abnormal or unusual patterns.

For example, in a remote video camera, the chip can be programmed to send a video back to the servers only when a specific type of car or something out of the ordinary is detected, such as an intruder.

This would be extremely beneficial for the Internet of Things (IOT), where every electrical and electronic device is connected to the Internet through a smart chip.

With a report by marketing research firm Gartner Inc predicting that 6.4 billion smart devices and appliances will be connected to the Internet by 2016, and will rise to 20.8 billion devices by 2020, reducing network traffic will be a priority for most companies.

Using NTU’s new chip, the devices can process and analyse the data on site, before sending back important details in a compressed package, instead of sending the whole data stream. This will reduce data usage by over a thousand times.

Asst Prof Basu is now in talks with Singapore Technologies Electronics Limited to adapt his smart chip that can significantly reduce power consumption and the amount of data transmitted by battery-operated remote sensors, such as video cameras.

The team is also looking to expand the applications of the chip into commercial products, such as to customise it for smart home sensor networks, in collaboration with a local electronics company.

The chip, measuring 5mm by 5mm can now be licensed by companies from NTU’s commercialisation arm, NTUitive.

Here’s a link to and a citation for the paper,

A 128-Channel Extreme Learning Machine-Based Neural Decoder for Brain Machine Interfaces by Yi Chen, Enyi Yao, Arindam Basu. IEEE Transactions on Biomedical Circuits and Systems, 2015; 1 DOI: 10.1109/TBCAS.2015.2483618

This paper is behind a paywall.

Australia

Earlier this month there was a Feb. 9, 2016 announcement about a planned human clinical trial in Australia for a new brain-machine interface (neural implant). Before proceeding with the news, here’s what this implant looks like,

Caption: This tiny device, the size of a small paperclip, is implanted in to a blood vessel next to the brain and can read electrical signals from the motor cortex, the brain's control centre. These signals can then be transmitted to an exoskeleton or wheelchair to give paraplegic patients greater mobility. Users will need to learn how to communicate with their machinery, but over time, it is thought it will become second nature, like driving or playing the piano. The first human trials are slated for 2017 in Melbourne, Australia. Credit: The University of Melbourne.

Caption: This tiny device, the size of a small paperclip, is implanted in to a blood vessel next to the brain and can read electrical signals from the motor cortex, the brain’s control centre. These signals can then be transmitted to an exoskeleton or wheelchair to give paraplegic patients greater mobility. Users will need to learn how to communicate with their machinery, but over time, it is thought it will become second nature, like driving or playing the piano. The first human trials are slated for 2017 in Melbourne, Australia. Credit: The University of Melbourne.

A Feb. 9, 2016 University of Melbourne press release (also on EurekAlert), which originated the news item, provides more detail,

Melbourne medical researchers have created a new minimally invasive brain-machine interface, giving people with spinal cord injuries new hope to walk again with the power of thought.

The brain machine interface consists of a stent-based electrode (stentrode), which is implanted within a blood vessel next to the brain, and records the type of neural activity that has been shown in pre-clinical trials to move limbs through an exoskeleton or to control bionic limbs.

The new device is the size of a small paperclip and will be implanted in the first in-human trial at The Royal Melbourne Hospital in 2017.

The results published today in Nature Biotechnology show the device is capable of recording high-quality signals emitted from the brain’s motor cortex, without the need for open brain surgery.

Principal author and Neurologist at The Royal Melbourne Hospital and Research Fellow at The Florey Institute of Neurosciences and the University of Melbourne, Dr Thomas Oxley, said the stentrode was revolutionary.

“The development of the stentrode has brought together leaders in medical research from The Royal Melbourne Hospital, The University of Melbourne and the Florey Institute of Neuroscience and Mental Health. In total 39 academic scientists from 16 departments were involved in its development,” Dr Oxley said.

“We have been able to create the world’s only minimally invasive device that is implanted into a blood vessel in the brain via a simple day procedure, avoiding the need for high risk open brain surgery.

“Our vision, through this device, is to return function and mobility to patients with complete paralysis by recording brain activity and converting the acquired signals into electrical commands, which in turn would lead to movement of the limbs through a mobility assist device like an exoskeleton. In essence this a bionic spinal cord.”

Stroke and spinal cord injuries are leading causes of disability, affecting 1 in 50 people. There are 20,000 Australians with spinal cord injuries, with the typical patient a 19-year old male, and about 150,000 Australians left severely disabled after stroke.

Co-principal investigator and biomedical engineer at the University of Melbourne, Dr Nicholas Opie, said the concept was similar to an implantable cardiac pacemaker – electrical interaction with tissue using sensors inserted into a vein, but inside the brain.

“Utilising stent technology, our electrode array self-expands to stick to the inside wall of a vein, enabling us to record local brain activity. By extracting the recorded neural signals, we can use these as commands to control wheelchairs, exoskeletons, prosthetic limbs or computers,” Dr Opie said.

“In our first-in-human trial, that we anticipate will begin within two years, we are hoping to achieve direct brain control of an exoskeleton for three people with paralysis.”

“Currently, exoskeletons are controlled by manual manipulation of a joystick to switch between the various elements of walking – stand, start, stop, turn. The stentrode will be the first device that enables direct thought control of these devices”

Neurophysiologist at The Florey, Professor Clive May, said the data from the pre-clinical study highlighted that the implantation of the device was safe for long-term use.

“Through our pre-clinical study we were able to successfully record brain activity over many months. The quality of recording improved as the device was incorporated into tissue,” Professor May said.

“Our study also showed that it was safe and effective to implant the device via angiography, which is minimally invasive compared with the high risks associated with open brain surgery.

“The brain-computer interface is a revolutionary device that holds the potential to overcome paralysis, by returning mobility and independence to patients affected by various conditions.”

Professor Terry O’Brien, Head of Medicine at Departments of Medicine and Neurology, The Royal Melbourne Hospital and University of Melbourne said the development of the stentrode has been the “holy grail” for research in bionics.

“To be able to create a device that can record brainwave activity over long periods of time, without damaging the brain is an amazing development in modern medicine,” Professor O’Brien said.

“It can also be potentially used in people with a range of diseases aside from spinal cord injury, including epilepsy, Parkinsons and other neurological disorders.”

The development of the minimally invasive stentrode and the subsequent pre-clinical trials to prove its effectiveness could not have been possible without the support from the major funding partners – US Defense Department DARPA [Defense Advanced Research Projects Agency] and Australia’s National Health and Medical Research Council.

So, DARPA is helping fund this, eh? Interesting but not a surprise given the agency’s previous investments in brain research and neuroprosthetics.

For those who like to get their news via video,

Here’s a link to and a citation for the paper,

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity by Thomas J Oxley, Nicholas L Opie, Sam E John, Gil S Rind, Stephen M Ronayne, Tracey L Wheeler, Jack W Judy, Alan J McDonald, Anthony Dornom, Timothy J H Lovell, Christopher Steward, David J Garrett, Bradford A Moffat, Elaine H Lui, Nawaf Yassi, Bruce C V Campbell, Yan T Wong, Kate E Fox, Ewan S Nurse, Iwan E Bennett, Sébastien H Bauquier, Kishan A Liyanage, Nicole R van der Nagel, Piero Perucca, Arman Ahnood et al. Nature Biotechnology (2016)  doi:10.1038/nbt.3428 Published online 08 February 2016

This paper is behind a paywall.

I wish the researchers in Singapore, Australia, and elsewhere, good luck!

Humans, computers, and a note of optimism

As an* antidote to my Jan. 4*, 2016 post titled: Nanotechnology and cybersecurity risks and if you’re looking to usher in 2016 on a hopeful note, this Dec. 31, 2015 Human Computation Institute news release on EurekAlert is very timely,

The combination of human and computer intelligence might be just what we need to solve the “wicked” problems of the world, such as climate change and geopolitical conflict, say researchers from the Human Computation Institute (HCI) and Cornell University.

In an article published in the journal Science, the authors present a new vision of human computation (the science of crowd-powered systems), which pushes beyond traditional limits, and takes on hard problems that until recently have remained out of reach.

Humans surpass machines at many things, ranging from simple pattern recognition to creative abstraction. With the help of computers, these cognitive abilities can be effectively combined into multidimensional collaborative networks that achieve what traditional problem-solving cannot.

Most of today’s human computation systems rely on sending bite-sized ‘micro-tasks’ to many individuals and then stitching together the results. For example, 165,000 volunteers in EyeWire have analyzed thousands of images online to help build the world’s most complete map of human retinal neurons.

This microtasking approach alone cannot address the tough challenges we face today, say the authors. A radically new approach is needed to solve “wicked problems” – those that involve many interacting systems that are constantly changing, and whose solutions have unforeseen consequences (e.g., corruption resulting from financial aid given in response to a natural disaster).

New human computation technologies can help. Recent techniques provide real-time access to crowd-based inputs, where individual contributions can be processed by a computer and sent to the next person for improvement or analysis of a different kind. This enables the construction of more flexible collaborative environments that can better address the most challenging issues.

This idea is already taking shape in several human computation projects, including YardMap.org, which was launched by the Cornell in 2012 to map global conservation efforts one parcel at a time.

“By sharing and observing practices in a map-based social network, people can begin to relate their individual efforts to the global conservation potential of living and working landscapes,” says Janis Dickinson, Professor and Director of Citizen Science at the Cornell Lab of Ornithology.

YardMap allows participants to interact and build on each other’s work – something that crowdsourcing alone cannot achieve. The project serves as an important model for how such bottom-up, socially networked systems can bring about scalable changes how we manage residential landscapes.

HCI has recently set out to use crowd-power to accelerate Cornell-based Alzheimer’s disease research. WeCureAlz.com combines two successful microtasking systems into an interactive analytic pipeline that builds blood flow models of mouse brains. The stardust@home system, which was used to search for comet dust in one million images of aerogel, is being adapted to identify stalled blood vessels, which will then be pinpointed in the brain by a modified version of the EyeWire system.

“By enabling members of the general public to play some simple online game, we expect to reduce the time to treatment discovery from decades to just a few years”, says HCI director and lead author, Dr. Pietro Michelucci. “This gives an opportunity for anyone, including the tech-savvy generation of caregivers and early stage AD patients, to take the matter into their own hands.”

Here’s a link to and a citation for the paper,

Human Computation; The power of crowds by Pietro Michelucci, and Janis L. Dickinson. Science 1 January 2016: Vol. 351 no. 6268 pp. 32-33 DOI: 10.1126/science.aad6499

This paper is behind a paywall but the abstract is freely available,

Human computation, a term introduced by Luis von Ahn (1), refers to distributed systems that combine the strengths of humans and computers to accomplish tasks that neither can do alone (2). The seminal example is reCAPTCHA, a Web widget used by 100 million people a day when they transcribe distorted text into a box to prove they are human. This free cognitive labor provides users with access to Web content and keeps websites safe from spam attacks, while feeding into a massive, crowd-powered transcription engine that has digitized 13 million articles from The New York Times archives (3). But perhaps the best known example of human computation is Wikipedia. Despite initial concerns about accuracy (4), it has become the key resource for all kinds of basic information. Information science has begun to build on these early successes, demonstrating the potential to evolve human computation systems that can model and address wicked problems (those that defy traditional problem-solving methods) at the intersection of economic, environmental, and sociopolitical systems.

*’and’ changed to ‘an’ and ‘Jan. 3, 2016’ changed to ‘Jan. 4, 2016’ on Jan. 4, 2016 at 1543 PDT.

A perovskite memristor with three stable resistive states

Thanks to Dexter Johnson’s Oct. 22, 2015 posting on his Nanoclast blog (on the IEEE [Institute of Electrical and Electronics Engineers]) website, I’ve found information about a second memristor with three terminals, aka, three stable resistive states,  (the first is mentioned in my April 10, 2015 posting). From Dexter’s posting (Note: Links have been removed),

Now researchers at ETH Zurich have designed a memristor device out of perovskite just 5 nanometres thick that has three stable resistive states, which means it can encode data as 0,1 and 2, or a “trit” as opposed to a “bit.”

The research, which was published in the journal ACS Nano, developed model devices that have two competing nonvolatile resistive switching processes. These switching processes can be alternatively triggered by the effective switching voltage and time applied to the device.

“Our component could therefore also be useful for a new type of IT (Information Technology) that is not based on binary logic, but on a logic that provides for information located ‘between’ the 0 and 1,” said Jennifer Rupp, professor in the Department of Materials at ETH Zurich, in a press release. “This has interesting implications for what is referred to as fuzzy logic, which seeks to incorporate a form of uncertainty into the processing of digital information. You could describe it as less rigid computing.”

An Oct. 19, 2015 Swiss National Science Foundation press release provides context for the research,

Two IT giants, Intel and HP, have entered a race to produce a commercial version of memristors, a new electronics component that could one day replace flash memory (DRAM) used in USB memory sticks, SD cards and SSD hard drives. “Basically, memristors require less energy since they work at lower voltages,” explains Jennifer Rupp, professor in the Department of Materials at ETH Zurich and holder of a SNSF professorship grant. “They can be made much smaller than today’s memory modules, and therefore offer much greater density. This means they can store more megabytes of information per square millimetre.” But currently memristors are only at the prototype stage. [emphasis mine]

There is a memristor-based product on the market as I noted in a Sept. 10, 2015 posting, although that may not be the type of memristive device that Rupp seems to be discussing. (Should you have problems accessing the Swiss National Science Foundation press release, you can find a lightly edited version (a brief [two sentences] history of the memristor has been left out) here on Azonano.

Jacopo Prisco wrote for CNN online in a March 2, 2015 article about memristors and Rupp’s work (Note: A link has been removed),

Simply put, the memristor could mean the end of electronics as we know it and the beginning of a new era called “ionics”.

The transistor, developed in 1947, is the main component of computer chips. It functions using a flow of electrons, whereas the memristor couples the electrons with ions, or electrically charged atoms.

In a transistor, once the flow of electrons is interrupted by, say, cutting the power, all information is lost. But a memristor can remember the amount of charge that was flowing through it, and much like a memory stick it will retain the data even when the power is turned off.

This can pave the way for computers that will instantly turn on and off like a light bulb and never lose data: the RAM, or memory, will no longer be erased when the machine is turned off, without the need to save anything to hard drives as with current technology.

Jennifer Rupp is a Professor of electrochemical materials at ETH Zurich, and she’s working with IBM to build a memristor-based machine.

Memristors, she points out, function in a way that is similar to a human brain: “Unlike a transistor, which is based on binary codes, a memristor can have multi-levels. You could have several states, let’s say zero, one half, one quarter, one third, and so on, and that gives us a very powerful new perspective on how our computers may develop in the future,” she told CNN’s Nick Glass.

This is the CNN interview with Rupp,

Prisco also provides an update about HP’s memristor-based product,

After manufacturing the first ever memristor, Hewlett Packard has been working for years on a new type of computer based on the technology. According to plans, it will launch by 2020.

Simply called “The Machine”, it uses “electrons for processing, photons for communication, and ions for storage.”

I first wrote about HP’s The Machine in a June 25, 2014 posting (scroll down about 40% of the way).

There are many academic teams researching memristors including a team at Northwestern University. I highlighted their announcement of a three-terminal version in an April 10, 2015 posting. While Rupp’s team achieved its effect with a perovskite substrate, the Northwestern team used a molybdenum disulfide (MoS2) substrate.

For anyone wanting to read the latest research from ETH, here’s a link to and a citation for the paper,

Uncovering Two Competing Switching Mechanisms for Epitaxial and Ultrathin Strontium Titanate-Based Resistive Switching Bits by Markus Kubicek, Rafael Schmitt, Felix Messerschmitt, and Jennifer L. M. Rupp. ACS Nano, Article ASAP DOI: 10.1021/acsnano.5b02752 Publication Date (Web): October 8, 2015

Copyright © 2015 American Chemical Society

This paper is behind a paywall.

Finally, should you find the commercialization aspects of the memristor story interesting, there’s a June 6, 2015 posting by Knowm CEO (chief executive officer) Alex Nugent waxes eloquent on HP Labs’ ‘memristor problem’ (Note: A link has been removed),

Today I read something that did not surprise me. HP has said that their memristor technology will be replaced by traditional DRAM memory for use in “The Machine”. This is not surprising for those of us who have been in the field since before HP’s memristor marketing engine first revved up in 2008. While I have to admit the miscommunication between HP’s research and business development departments is starting to get really old, I do understand the problem, or at least part of it.

There are two ways to develop memristors. The first way is to force them to behave as you want them to behave. Most memristors that I have seen do not behave like fast, binary, non-volatile, deterministic switches. This is a problem because this is how HP wants them to behave. Consequently a perception has been created that memristors are for non-volatile fast memory. HP wants a drop-in replacement for standard memory because this is a large and established market. Makes sense of course, but its not the whole story on memristors.

Memristors exhibit a huge range of amazing phenomena. Some are very fast to switch but operate probabilistically. Others can be changed a little bit at a time and are ideal for learning. Still others have capacitance (with memory), or act as batteries. I’ve even seen some devices that can be programmed to be a capacitor or a resistor or a memristor. (Seriously).

Nugent, whether you agree with him or not provides, some fascinating insight. In the excerpt I’ve included here, he seems to provide confirmation that it’s possible to state ‘there are no memristors on the market’ and ‘there are memristors on the market’ because different devices are being called memristors.