Monthly Archives: October 2017

Nondirect relationships between the number of hydrogen bonds in DNA pairs and their relative strengths (three can be less than two)

Michael Berger’s Oct. 10, 2017 Nanowerk Spotlight article features research from the Institut Català de Nanociència i Nanotecnologia, (Catalan Institute of Nanoscience and Nanotechnology and acronym ICN2) which has nothing to do with recent vote on independence (for more, see this Oct. 23, 2017 article about how countries such as ‘Catalonia’ and others do and don’t gain independence in The Atlantic),

This is the first report on the electrical characterization of DNA with intrabond resolution.

Specifically, it quantifies electrical forces due to a single hydrogen bond in DNA and provides proof of a non-direct relationship between the number of hydrogen bonds in DNA pairs and the relative strengths of such pairs.

Such understanding of the relative strengths of the forces involved in the specific bonding of DNA as well as its electrical origin provides physical foundations to control mechanisms associated with DNA stability. It could help to develop new methods for the understanding, characterization; and control of relevant events originated at intrabond scales e.g. controlled DNA repair and damage; controlled modification of the expression of the genome; and communications below the single bond limit.

A blackboard representation of the manuscript’s key message: the quantification of the relative strengths between base pairs in DNA due to zipping hydrogen bonds might place on doubt such mechanisms regarding the interpretation of thermodynamic properties of DNA based on the assumption that A/T pairs are weaker than G/C pairs due to the sole difference in the number of hydrogen bonds, 2 and 3 respectively. (Image: Dr. Yamila García-Martínez)

Generally, being able to control DNA stability at the single bond level by means of electromagnetic interactions opens new avenues to induce modifications of the replication and transcription processes of DNA by means of noncontact methods.

….

Going forward, the researchers will study the effects of external electromagnetic fields on DNA at the level of single bond events. This will have not only an enormous interest in the medical field but also in nanotechnology where it would open the door to non-contact atomic manipulation of DNA – the analogue to the CRISPR gene editing method [emphasis mine] but using electromagnetic fields to drive changes in DNA.

Interesting stuff, eh?

Here’s a link to and a citation for the paper,

Unveiled electric profiles within hydrogen bonds suggest DNA base pairs with similar bond strengths by Y. B. Ruiz-Blanco, Y. Almeida, C. M. Sotomayor-Torres, Y. García. PLOS [Public Library of Science] https://doi.org/10.1371/journal.pone.0185638 Published: October 5, 2017

This paper is open access.

A flexible, organic battery from Northern Ireland

A team from Northern Ireland seems to have made a splash in the race to develop a flexible, environmentally friendly battery. From a Sept. 13, 2017 news item on phys.org,

Experts at Queen’s University Belfast have designed a flexible and organic alternative to the rigid batteries that power up medical implants.

Currently, devices such as pacemakers and defibrillators are fitted with rigid and metal based batteries, which can cause patient discomfort.

Dr Geetha Srinivasan and a team of young researchers from Queen’s University Ionic Liquid Laboratories (QUILL) Research Centre, have now developed a flexible supercapacitor with a longer cycle life, which could power body sensors.

Courtesy: Queen’s University Belfast

A Sept. 13, 2017 Queen’s University Belfast press release (also on EurekAlert), which originated the news item, delves further,

The flexible device is made up of non-flammable electrolytes and organic composites, which are safe to the human body. It can also be easily decomposed without incurring the major costs associated with recycling or disposing off metal based batteries.

The findings, which have been published in Energy Technology and Green Chemistry, show that the device could be manufactured using readily available natural feedstock, rather than sophisticated and expensive metals or semiconductors.

Dr Srinivasan explains: “In modern society, we all increasingly depend on portable electronics such as smartphones and laptops in our everyday lives and this trend has spread to other important areas such as healthcare devices.

“In medical devices such as pacemakers and defibrillators there are two implants, one which is fitted in the heart and another which holds the metal based, rigid batteries – this is implanted under the skin.

“The implant under the skin is wired to the device and can cause patients discomfort as it is rubs against the skin. For this reason batteries need to be compatible to the human body and ideally we would like them to be flexible so that they can adapt to body shapes.”

Dr Srinivasan adds: “At Queen’s University Belfast we have designed a flexible energy storage device, which consists of conducting polymer – biopolymer composites as durable electrodes and ionic liquids as safer electrolytes.

“The device we have created has a longer life-cycle, is non-flammable, has no leakage issues and above all, it is more flexible for placing within the body.”

Environmentally friendly

While the findings show that there are many advantages in the medical world, the organic storage device could also provide solutions in wearable electronics and portable electronic devices, making these more flexible.

Ms Marta Lorenzo, PhD researcher on the project at Queen’s University Belfast, commented: “Although this research could be a potential solution to a global problem, the actual supercapacitor assembly is a straightforward process.”

Dr Srinivasan says: “There is also opportunity to fabricate task-specific supercapacitors. This means that their properties can be tuned and also manufactured using environmentally friendly methods, which is important if they are to be produced on a large scale, for example in powering portable personal electronic devices.”

Here are links and citations to the two papers mentioned in the press release,

Durable Flexible Supercapacitors Utilizing the Multifunctional Role of Ionic Liquids by Marta Lorenzo and Dr Geetha Srinivasan. Energy Technology. DOI: 10.1002/ente.201700407 First published: 23 August 2017

Intrinsically flexible electronic materials for smart device applications by Marta Lorenzo, Biyun Zhu, and Geetha Srinivasan. Green Chem., 2016,18, 3513-3517 DOI: 10.1039/C6GC00826G First published on 20 May 2016

The first paper is open access and the second paper is behind a paywall.

Brain composer

This is a representation of the work they are doing on brain-computer interfaces (BCI) at the Technical University of Graz (TU Graz; Austria),

A Sept. 11, 2017 news item on phys.org announces the research into thinking melodies turning them into a musical score,

TU Graz researchers develop new brain-computer interface application that allows music to be composed by the power of thought. They have published their results in the current issue of the journal PLOS ONE.

Brain-computer interfaces (BCI) can replace bodily functions to a certain degree. Thanks to BCI, physically impaired persons can control special prostheses via their minds, surf the internet and write emails.

A group led by BCI expert Gernot Müller-Putz from TU Graz’s Institute of Neural Engineering shows that experiences of quite a different tone can be sounded from the keys of brain-computer interfaces. Derived from an established BCI method for writing, the team has developed a new application by which music can be composed and transferred onto a musical score through the power of thought. It employs a special cap that measures brain waves, the adapted BCI, music composition software, and a bit of musical knowledge.

A Sept. 6, 2017 TU Graz press release by Suzanne Eigner, which originated the news item, explains the research in more detail,

The basic principle of the BCI method used, which is called P300, can be briefly described: various options, such as letters or notes, pauses, chords, etc. flash by one after the other in a table. If you’re trained and can focus on the desired option while it lights up, you cause a minute change in your brain waves. The BCI recognises this change and draws conclusions about the chosen option.

Musical test persons

18 test persons chosen for the study by Gernot Müller-Putz, Andreas Pinegger and Selina C. Wriessnegger from TU Graz’s Institute of Neural Engineering as well as Hannah Hiebel, meanwhile at the Institute of Cognitive Psychology & Neuroscience at the University of Graz, had to “think” melodies onto a musical score. All test subjects were of sound bodily health during the study and had a certain degree of basic musical and compositional knowledge since they all played musical instruments to some degree. Among the test persons was the late Graz composer and clarinettist, Franz Cibulka. “The results of the BCI compositions can really be heard. And what is more important: the test persons enjoyed it. After a short training session, all of them could start composing and seeing their melodies on the score and then play them. The very positive results of the study with bodily healthy test persons are the first step in a possible expansion of the BCI composition to patients,” stresses Müller-Putz.

Sideshow of BCI research

This little-noticed sideshow of the lively BCI research at TU Graz, with its distinct focus on disabled persons, shows us which other avenues may yet be worth exploring. Meanwhile there are some initial attempts at BCI systems on smart phones. This makes it easier for people to use BCI applications, since the smart phone as powerful computer is becoming part of the BCI system. It is thus conceivable, for instance, to have BCI apps which can analyse brain signals for various applications. “20 years ago, the idea of composing a piece of music using the power of the mind was unimaginable. Now we can do it, and at the same time have tens of new, different ideas which are in part, once again, a long way from becoming reality. We still need a bit more time before it is mature enough for daily applications. The BCI community is working in many directions at high pressure.

Here’s a link to and a citation for the paper,

Composing only by thought: Novel application of the P300 brain-computer interface by Andreas Pinegger, Hannah Hiebel, Selina C. Wriessnegger, Gernot R. Müller-Putz. PLOS https://doi.org/10.1371/journal.pone.0181584 Published: September 6, 2017

This paper is open access.

This BCI ‘sideshow’ reminded me of The Music Man, a musical by Meredith Wilson. It was both a play and a film  and I’ve only ever seen the 1962 film. It features a con man, Harold Hill, who sells musical instruments and uniforms in small towns in Iowa. He has no musical training but while he’s conning the townspeople he convinces them that he can provide musical training with his ‘think method’. After falling in love with one of the townsfolk, he is hunted down and made to prove his method works. This is a clip from a Broadway revival of the play where Harold Hill is hoping that his ‘think method’ while yield results,

Of course, the people in this study had musicaltraining so they could think a melody into a musical score but I find the echo from the past amusing nonetheless.

Vampire nanogenerators: 2017

Researchers have been working on ways to harvest energy from bloodstreams. I last wrote about this type of research in an April 3, 2009 posting about ‘vampire batteries ‘(for use in pacemakers). The latest work according to a Sept. 8, 2017 news item on Nanowerk comes from China,

Men build dams and huge turbines to turn the energy of waterfalls and tides into electricity. To produce hydropower on a much smaller scale, Chinese scientists have now developed a lightweight power generator based on carbon nanotube fibers suitable to convert even the energy of flowing blood in blood vessels into electricity. They describe their innovation in the journal Angewandte Chemie (“A One-Dimensional Fluidic Nanogenerator with a High Power Conversion Efficiency”)

A Sept. 8, 2017 Wiley Publishing news release (also on EurekAlert), which originated the news item, expands on the theme,

For thousands of years, people have used the energy of flowing or falling water for their purposes, first to power mechanical engines such as watermills, then to generate electricity by exploiting height differences in the landscape or sea tides. Using naturally flowing water as a sustainable power source has the advantage that there are (almost) no dependencies on weather or daylight. Even flexible, minute power generators that make use of the flow of biological fluids are conceivable. How such a system could work is explained by a research team from Fudan University in Shanghai, China. Huisheng Peng and his co-workers have developed a fiber with a thickness of less than a millimeter that generates electrical power when surrounded by flowing saline solution—in a thin tube or even in a blood vessel.

The construction principle of the fiber is quite simple. An ordered array of carbon nanotubes was continuously wrapped around a polymeric core. Carbon nanotubes are well known to be electroactive and mechanically stable; they can be spun and aligned in sheets. In the as-prepared electroactive threads, the carbon nanotube sheets coated the fiber core with a thickness of less than half a micron. For power generation, the thread or “fiber-shaped fluidic nanogenerator” (FFNG), as the authors call it, was connected to electrodes and immersed into flowing water or simply repeatedly dipped into a saline solution. “The electricity was derived from the relative movement between the FFNG and the solution,” the scientists explained. According to the theory, an electrical double layer is created around the fiber, and then the flowing solution distorts the symmetrical charge distribution, generating an electricity gradient along the long axis.

The power output efficiency of this system was high. Compared with other types of miniature energy-harvesting devices, the FFNG was reported to show a superior power conversion efficiency of more than 20%. Other advantages are elasticity, tunability, lightweight, and one-dimensionality, thus offering prospects of exciting technological applications. The FFNG can be made stretchable just by spinning the sheets around an elastic fiber substrate. If woven into fabrics, wearable electronics become thus a very interesting option for FFNG application. Another exciting application is the harvesting of electrical energy from the bloodstream for medical applications. First tests with frog nerves proved to be successful.

Here’s a link to and a citation for the paper,

A One-Dimensional Fluidic Nanogenerator with a High Power Conversion Efficiency by Yifan Xu, Dr. Peining Chen, Jing Zhang, Songlin Xie, Dr. Fang Wan, Jue Deng, Dr. Xunliang Cheng, Yajie Hu, Meng Liao, Dr. Bingjie Wang, Dr. Xuemei Sun, and Prof. Dr. Huisheng Peng. Angewandte Chemie International Edition DOI: 10.1002/anie.201706620 Version of Record online: 7 SEP 2017

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

This paper is behind a paywall.

Hallucinogenic molecules and the brain

Psychedelic drugs seems to be enjoying a ‘moment’. After decades of being vilified and  declared illegal (in many jurisdictions), psychedelic (or hallucinogenic) drugs are once again being tested for use in therapy. A Sept. 1, 2017 article by Diana Kwon for The Scientist describes some of the latest research (I’ve excerpted the section on molecules; Note: Links have been removed),

Mind-bending molecules

© SEAN MCCABE

All the classic psychedelic drugs—psilocybin, LSD, and N,N-dimethyltryptamine (DMT), the active component in ayahuasca—activate serotonin 2A (5-HT2A) receptors, which are distributed throughout the brain. In all likelihood, this receptor plays a key role in the drugs’ effects. Krähenmann [Rainer Krähenmann, a psychiatrist and researcher at the University of Zurich]] and his colleagues in Zurich have discovered that ketanserin, a 5-HT2A receptor antagonist, blocks LSD’s hallucinogenic properties and prevents individuals from entering a dreamlike state or attributing personal relevance to the experience.12,13

Other research groups have found that, in rodent brains, 2,5-dimethoxy-4-iodoamphetamine (DOI), a highly potent and selective 5-HT2A receptor agonist, can modify the expression of brain-derived neurotrophic factor (BDNF)—a protein that, among other things, regulates neuronal survival, differentiation, and synaptic plasticity. This has led some scientists to hypothesize that, through this pathway, psychedelics may enhance neuroplasticity, the ability to form new neuronal connections in the brain.14 “We’re still working on that and trying to figure out what is so special about the receptor and where it is involved,” says Katrin Preller, a postdoc studying psychedelics at the University of Zurich. “But it seems like this combination of serotonin 2A receptors and BDNF leads to a kind of different organizational state in the brain that leads to what people experience under the influence of psychedelics.”

This serotonin receptor isn’t limited to the central nervous system. Work by Charles Nichols, a pharmacology professor at Louisiana State University, has revealed that 5-HT2A receptor agonists can reduce inflammation throughout the body. Nichols and his former postdoc Bangning Yu stumbled upon this discovery by accident, while testing the effects of DOI on smooth muscle cells from rat aortas. When they added this drug to the rodent cells in culture, it blocked the effects of tumor necrosis factor-alpha (TNF-α), a key inflammatory cytokine.

“It was completely unexpected,” Nichols recalls. The effects were so bewildering, he says, that they repeated the experiment twice to convince themselves that the results were correct. Before publishing the findings in 2008,15 they tested a few other 5-HT2A receptor agonists, including LSD, and found consistent anti-inflammatory effects, though none of the drugs’ effects were as strong as DOI’s. “Most of the psychedelics I have tested are about as potent as a corticosteroid at their target, but there’s something very unique about DOI that makes it much more potent,” Nichols says. “That’s one of the mysteries I’m trying to solve.”

After seeing the effect these drugs could have in cells, Nichols and his team moved on to whole animals. When they treated mouse models of system-wide inflammation with DOI, they found potent anti-inflammatory effects throughout the rodents’ bodies, with the strongest effects in the small intestine and a section of the main cardiac artery known as the aortic arch.16 “I think that’s really when it felt that we were onto something big, when we saw it in the whole animal,” Nichols says.

The group is now focused on testing DOI as a potential therapeutic for inflammatory diseases. In a 2015 study, they reported that DOI could block the development of asthma in a mouse model of the condition,17 and last December, the team received a patent to use DOI for four indications: asthma, Crohn’s disease, rheumatoid arthritis, and irritable bowel syndrome. They are now working to move the treatment into clinical trials. The benefit of using DOI for these conditions, Nichols says, is that because of its potency, only small amounts will be required—far below the amounts required to produce hallucinogenic effects.

In addition to opening the door to a new class of diseases that could benefit from psychedelics-inspired therapy, Nichols’s work suggests “that there may be some enduring changes that are mediated through anti-inflammatory effects,” Griffiths [Roland Griffiths, a psychiatry professor at Johns Hopkins University] says. Recent studies suggest that inflammation may play a role in a number of psychological disorders, including depression18 and addiction.19

“If somebody has neuroinflammation and that’s causing depression, and something like psilocybin makes it better through the subjective experience but the brain is still inflamed, it’s going to fall back into the depressed rut,” Nichols says. But if psilocybin is also treating the inflammation, he adds, “it won’t have that rut to fall back into.”

If it turns out that psychedelics do have anti-inflammatory effects in the brain, the drugs’ therapeutic uses could be even broader than scientists now envision. “In terms of neurodegenerative disease, every one of these disorders is mediated by inflammatory cytokines,” says Juan Sanchez-Ramos, a neuroscientist at the University of South Florida who in 2013 reported that small doses of psilocybin could promote neurogenesis in the mouse hippocampus.20 “That’s why I think, with Alzheimer’s, for example, if you attenuate the inflammation, it could help slow the progression of the disease.”

For anyone who was never exposed to the anti-hallucinogenic drug campaigns, this turn of events is mindboggling. There was a great deal of concern especially with LSD in the 1960s and it was not entirely unfounded. In my own family, a distant cousin, while under the influence of the drug, jumped off a building believing he could fly.  So, Kwon’s story opening with a story about someone being treated successfully for depression with a psychedelic drug was surprising to me . Why these drugs are being used successfully for psychiatric conditions when so much damage was apparently done under the influence in decades past may have something to do with taking the drugs in a controlled environment and, possibly, smaller dosages.

Nanowire fingerprint technology

Apparently this technology from France’s Laboratoire d’électronique des technologies de l’information (CEA-Leti) will make fingerprinting more reliable. From a Sept. 5, 2017 news item on Nanowerk,

Leti today announced that the European R&D project known as PiezoMAT has developed a pressure-based fingerprint sensor that enables resolution more than twice as high as currently required by the U.S. Federal Bureau of Investigation (FBI).

The project’s proof of concept demonstrates that a matrix of interconnected piezoelectric zinc-oxide (ZnO) nanowires grown on silicon can reconstruct the smallest features of human fingerprints at 1,000 dots per inch (DPI).

“The pressure-based fingerprint sensor derived from the integration of piezo-electric ZnO nanowires grown on silicon opens the path to ultra-high resolution fingerprint sensors, which will be able to reach resolution much higher than 1,000 DPI,” said Antoine Viana, Leti’s project manager. “This technology holds promise for significant improvement in both security and identification applications.”

A Sept. 5, 2017 Leti press release, which originated the news item, delves further,

The eight-member project team of European companies, universities and research institutes fabricated a demonstrator embedding a silicon chip with 250 pixels, and its associated electronics for signal collection and post-processing. The chip was designed to demonstrate the concept and the major technological achievements, not the maximum potential nanowire integration density. Long-term development will pursue full electronics integration for optimal sensor resolution.

The project also provided valuable experience and know-how in several key areas, such as optimization of seed-layer processing, localized growth of well-oriented ZnO nanowires on silicon substrates, mathematical modeling of complex charge generation, and synthesis of new polymers for encapsulation. The research and deliverables of the project have been presented in scientific journals and at conferences, including Eurosensors 2016 in Budapest.

The 44-month, €2.9 million PiezoMAT (PIEZOelectric nanowire MATrices) research project was funded by the European Commission in the Seventh Framework Program. Its partners include:

  • Leti (Grenoble, France): A leading European center in the field of microelectronics, microtechnology and nanotechnology R&D, Leti is one of the three institutes of the Technological Research Division at CEA, the French Alternative Energies and Atomic Energy Commission. Leti’s activities span basic and applied research up to pilot industrial lines. www.leti-cea.com/cea-tech/leti/english
  • Fraunhofer IAF (Freiburg, Germany): Fraunhofer IAF, one of the leading research facilities worldwide in the field of III-V semiconductors, develops electronic and optical devices based on modern micro- and nanostructures. Fraunhofer IAF’s technologies find applications in areas such as security, energy, communication, health, and mobility. www.iaf.fraunhofer.de/en
  • Centre for Energy Research, Hungarian Academy of Sciences (Budapest, Hungary):  The Institute for Technical Physics and Materials Science, one of the institutes of the Research Centre, conducts interdisciplinary research on complex functional materials and nanometer-scale structures, exploration of physical, chemical, and biological principles, and their exploitation in integrated micro- and nanosystems www.mems.hu, www.energia.mta.hu/en
  • Universität Leipzig (Leipzig, Germany): Germany’s second-oldest university with continuous teaching, established in 1409, hosts about 30,000 students in liberal arts, medicine and natural sciences. One of its scientific profiles is “Complex Matter”, and contributions to PIEZOMAT are in the field of nanostructures and wide gap materials. www.zv.uni-leipzig.de/en/
  • Kaunas University of Technology (Kaunas, Lithuania): One of the largest technical universities in the Baltic States, focusing its R&D activities on novel materials, smart devices, advanced measurement techniques and micro/nano-technologies. The Institute of Mechatronics specializes on multi-physics simulation and dynamic characterization of macro/micro-scale transducers with well-established expertise in the field of piezoelectric devices. http://en.ktu.lt/
  • SPECIFIC POLYMERS (Castries, France): SME with twelve employees and an annual turnover of about 1M€, SPECIFIC POLYMERS acts as an R&D service provider and scale-up producer in the field of functional polymers with high specificity (>1000 polymers in catalogue; >500 customers; >50 countries). www.specificpolymers.fr/
  • Tyndall National Institute (Cork, Ireland): Tyndall National Institute is one of Europe’s leading research centres in Information and Communications Technology (ICT) research and development and the largest facility of its type in Ireland. The Institute employs over 460 researchers, engineers and support staff, with a full-time graduate cohort of 135 students. With a network of 200 industry partners and customers worldwide, Tyndall generates around €30M income each year, 85% from competitively won contracts nationally and internationally. Tyndall is a globally leading Institute in its four core research areas of Photonics, Microsystems, Micro/Nanoelectronics and Theory, Modeling and Design. www.tyndall.ie/
  • OT-Morpho (Paris, France): OT-Morpho is a world leader in digital security & identification technologies with the ambition to empower citizens and consumers alike to interact, pay, connect, commute, travel and even vote in ways that are now possible in a connected world. As our physical and digital, civil and commercial lifestyles converge, OT-Morpho stands precisely at that crossroads to leverage the best in security and identity technologies and offer customized solutions to a wide range of international clients from key industries, including Financial services, Telecom, Identity, Security and IoT. With close to €3bn in revenues and more than 14,000 employees, OT-Morpho is the result of the merger between OT (Oberthur Technologies) and Safran Identity & Security (Morpho) completed in 31 May 2017. Temporarily designated by the name “OT-Morpho”, the new company will unveil its new name in September 2017. For more information, visit www.morpho.com and www.oberthur.com

I have tended to take fingerprint technology for granted but last fall (2016) I stumbled on a report suggesting that forensic sciences, including fingerprinting, was perhaps not as conclusive as one might expect after watching fictional police procedural television programmes. My Sept. 23, 2016 posting features the US President’s Council of Advisors on Science and Technology (PCAST) released a report (‘Forensic Science in Criminal Courts: Ensuring Scientific Validity of Feature-Comparison Methods‘ 174 pp PDF).

Robots in Vancouver and in Canada (two of two)

This is the second of a two-part posting about robots in Vancouver and Canada. The first part included a definition, a brief mention a robot ethics quandary, and sexbots. This part is all about the future. (Part one is here.)

Canadian Robotics Strategy

Meetings were held Sept. 28 – 29, 2017 in, surprisingly, Vancouver. (For those who don’t know, this is surprising because most of the robotics and AI research seems to be concentrated in eastern Canada. if you don’t believe me take a look at the speaker list for Day 2 or the ‘Canadian Stakeholder’ meeting day.) From the NSERC (Natural Sciences and Engineering Research Council) events page of the Canadian Robotics Network,

Join us as we gather robotics stakeholders from across the country to initiate the development of a national robotics strategy for Canada. Sponsored by the Natural Sciences and Engineering Research Council of Canada (NSERC), this two-day event coincides with the 2017 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2017) in order to leverage the experience of international experts as we explore Canada’s need for a national robotics strategy.

Where
Vancouver, BC, Canada

When
Thursday September 28 & Friday September 29, 2017 — Save the date!

Download the full agenda and speakers’ list here.

Objectives

The purpose of this two-day event is to gather members of the robotics ecosystem from across Canada to initiate the development of a national robotics strategy that builds on our strengths and capacities in robotics, and is uniquely tailored to address Canada’s economic needs and social values.

This event has been sponsored by the Natural Sciences and Engineering Research Council of Canada (NSERC) and is supported in kind by the 2017 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2017) as an official Workshop of the conference.  The first of two days coincides with IROS 2017 – one of the premiere robotics conferences globally – in order to leverage the experience of international robotics experts as we explore Canada’s need for a national robotics strategy here at home.

Who should attend

Representatives from industry, research, government, startups, investment, education, policy, law, and ethics who are passionate about building a robust and world-class ecosystem for robotics in Canada.

Program Overview

Download the full agenda and speakers’ list here.

DAY ONE: IROS Workshop 

“Best practices in designing effective roadmaps for robotics innovation”

Thursday September 28, 2017 | 8:30am – 5:00pm | Vancouver Convention Centre

Morning Program:“Developing robotics innovation policy and establishing key performance indicators that are relevant to your region” Leading international experts share their experience designing robotics strategies and policy frameworks in their regions and explore international best practices. Opening Remarks by Prof. Hong Zhang, IROS 2017 Conference Chair.

Afternoon Program: “Understanding the Canadian robotics ecosystem” Canadian stakeholders from research, industry, investment, ethics and law provide a collective overview of the Canadian robotics ecosystem. Opening Remarks by Ryan Gariepy, CTO of Clearpath Robotics.

Thursday Evening Program: Sponsored by Clearpath Robotics  Workshop participants gather at a nearby restaurant to network and socialize.

Learn more about the IROS Workshop.

DAY TWO: NSERC-Sponsored Canadian Robotics Stakeholder Meeting
“Towards a national robotics strategy for Canada”

Friday September 29, 2017 | 8:30am – 5:00pm | University of British Columbia (UBC)

On the second day of the program, robotics stakeholders from across the country gather at UBC for a full day brainstorming session to identify Canada’s unique strengths and opportunities relative to the global competition, and to align on a strategic vision for robotics in Canada.

Friday Evening Program: Sponsored by NSERC Meeting participants gather at a nearby restaurant for the event’s closing dinner reception.

Learn more about the Canadian Robotics Stakeholder Meeting.

I was glad to see in the agenda that some of the international speakers represented research efforts from outside the usual Europe/US axis.

I have been in touch with one of the organizers (also mentioned in part one with regard to robot ethics), Ajung Moon (her website is here), who says that there will be a white paper available on the Canadian Robotics Network website at some point in the future. I’ll keep looking for it and, in the meantime, I wonder what the 2018 Canadian federal budget will offer robotics.

Robots and popular culture

For anyone living in Canada or the US, Westworld (television series) is probably the most recent and well known ‘robot’ drama to premiere in the last year.As for movies, I think Ex Machina from 2014 probably qualifies in that category. Interestingly, both Westworld and Ex Machina seem quite concerned with sex with Westworld adding significant doses of violence as another  concern.

I am going to focus on another robot story, the 2012 movie, Robot & Frank, which features a care robot and an older man,

Frank (played by Frank Langella), a former jewel thief, teaches a robot the skills necessary to rob some neighbours of their valuables. The ethical issue broached in the film isn’t whether or not the robot should learn the skills and assist Frank in his thieving ways although that’s touched on when Frank keeps pointing out that planning his heist requires he live more healthily. No, the problem arises afterward when the neighbour accuses Frank of the robbery and Frank removes what he believes is all the evidence. He believes he’s going successfully evade arrest until the robot notes that Frank will have to erase its memory in order to remove all of the evidence. The film ends without the robot’s fate being made explicit.

In a way, I find the ethics query (was the robot Frank’s friend or just a machine?) posed in the film more interesting than the one in Vikander’s story, an issue which does have a history. For example, care aides, nurses, and/or servants would have dealt with requests to give an alcoholic patient a drink. Wouldn’t there  already be established guidelines and practices which could be adapted for robots? Or, is this question made anew by something intrinsically different about robots?

To be clear, Vikander’s story is a good introduction and starting point for these kinds of discussions as is Moon’s ethical question. But they are starting points and I hope one day there’ll be a more extended discussion of the questions raised by Moon and noted in Vikander’s article (a two- or three-part series of articles? public discussions?).

How will humans react to robots?

Earlier there was the contention that intimate interactions with robots and sexbots would decrease empathy and the ability of human beings to interact with each other in caring ways. This sounds a bit like the argument about smartphones/cell phones and teenagers who don’t relate well to others in real life because most of their interactions are mediated through a screen, which many seem to prefer. It may be partially true but, arguably,, books too are an antisocial technology as noted in Walter J. Ong’s  influential 1982 book, ‘Orality and Literacy’,  (from the Walter J. Ong Wikipedia entry),

A major concern of Ong’s works is the impact that the shift from orality to literacy has had on culture and education. Writing is a technology like other technologies (fire, the steam engine, etc.) that, when introduced to a “primary oral culture” (which has never known writing) has extremely wide-ranging impacts in all areas of life. These include culture, economics, politics, art, and more. Furthermore, even a small amount of education in writing transforms people’s mentality from the holistic immersion of orality to interiorization and individuation. [emphases mine]

So, robotics and artificial intelligence would not be the first technologies to affect our brains and our social interactions.

There’s another area where human-robot interaction may have unintended personal consequences according to April Glaser’s Sept. 14, 2017 article on Slate.com (Note: Links have been removed),

The customer service industry is teeming with robots. From automated phone trees to touchscreens, software and machines answer customer questions, complete orders, send friendly reminders, and even handle money. For an industry that is, at its core, about human interaction, it’s increasingly being driven to a large extent by nonhuman automation.

But despite the dreams of science-fiction writers, few people enter a customer-service encounter hoping to talk to a robot. And when the robot malfunctions, as they so often do, it’s a human who is left to calm angry customers. It’s understandable that after navigating a string of automated phone menus and being put on hold for 20 minutes, a customer might take her frustration out on a customer service representative. Even if you know it’s not the customer service agent’s fault, there’s really no one else to get mad at. It’s not like a robot cares if you’re angry.

When human beings need help with something, says Madeleine Elish, an anthropologist and researcher at the Data and Society Institute who studies how humans interact with machines, they’re not only looking for the most efficient solution to a problem. They’re often looking for a kind of validation that a robot can’t give. “Usually you don’t just want the answer,” Elish explained. “You want sympathy, understanding, and to be heard”—none of which are things robots are particularly good at delivering. In a 2015 survey of over 1,300 people conducted by researchers at Boston University, over 90 percent of respondents said they start their customer service interaction hoping to speak to a real person, and 83 percent admitted that in their last customer service call they trotted through phone menus only to make their way to a human on the line at the end.

“People can get so angry that they have to go through all those automated messages,” said Brian Gnerer, a call center representative with AT&T in Bloomington, Minnesota. “They’ve been misrouted or been on hold forever or they pressed one, then two, then zero to speak to somebody, and they are not getting where they want.” And when people do finally get a human on the phone, “they just sigh and are like, ‘Thank God, finally there’s somebody I can speak to.’ ”

Even if robots don’t always make customers happy, more and more companies are making the leap to bring in machines to take over jobs that used to specifically necessitate human interaction. McDonald’s and Wendy’s both reportedly plan to add touchscreen self-ordering machines to restaurants this year. Facebook is saturated with thousands of customer service chatbots that can do anything from hail an Uber, retrieve movie times, to order flowers for loved ones. And of course, corporations prefer automated labor. As Andy Puzder, CEO of the fast-food chains Carl’s Jr. and Hardee’s and former Trump pick for labor secretary, bluntly put it in an interview with Business Insider last year, robots are “always polite, they always upsell, they never take a vacation, they never show up late, there’s never a slip-and-fall, or an age, sex, or race discrimination case.”

But those robots are backstopped by human beings. How does interacting with more automated technology affect the way we treat each other? …

“We know that people treat artificial entities like they’re alive, even when they’re aware of their inanimacy,” writes Kate Darling, a researcher at MIT who studies ethical relationships between humans and robots, in a recent paper on anthropomorphism in human-robot interaction. Sure, robots don’t have feelings and don’t feel pain (not yet, anyway). But as more robots rely on interaction that resembles human interaction, like voice assistants, the way we treat those machines will increasingly bleed into the way we treat each other.

It took me a while to realize that what Glaser is talking about are AI systems and not robots as such. (sigh) It’s so easy to conflate the concepts.

AI ethics (Toby Walsh and Suzanne Gildert)

Jack Stilgoe of the Guardian published a brief Oct. 9, 2017 introduction to his more substantive (30 mins.?) podcast interview with Dr. Toby Walsh where they discuss stupid AI amongst other topics (Note: A link has been removed),

Professor Toby Walsh has recently published a book – Android Dreams – giving a researcher’s perspective on the uncertainties and opportunities of artificial intelligence. Here, he explains to Jack Stilgoe that we should worry more about the short-term risks of stupid AI in self-driving cars and smartphones than the speculative risks of super-intelligence.

Professor Walsh discusses the effects that AI could have on our jobs, the shapes of our cities and our understandings of ourselves. As someone developing AI, he questions the hype surrounding the technology. He is scared by some drivers’ real-world experimentation with their not-quite-self-driving Teslas. And he thinks that Siri needs to start owning up to being a computer.

I found this discussion to cast a decidedly different light on the future of robotics and AI. Walsh is much more interested in discussing immediate issues like the problems posed by ‘self-driving’ cars. (Aside: Should we be calling them robot cars?)

One ethical issue Walsh raises is with data regarding accidents. He compares what’s happening with accident data from self-driving (robot) cars to how the aviation industry handles accidents. Hint: accident data involving air planes is shared. Would you like to guess who does not share their data?

Sharing and analyzing data and developing new safety techniques based on that data has made flying a remarkably safe transportation technology.. Walsh argues the same could be done for self-driving cars if companies like Tesla took the attitude that safety is in everyone’s best interests and shared their accident data in a scheme similar to the aviation industry’s.

In an Oct. 12, 2017 article by Matthew Braga for Canadian Broadcasting Corporation (CBC) news online another ethical issue is raised by Suzanne Gildert (a participant in the Canadian Robotics Roadmap/Strategy meetings mentioned earlier here), Note: Links have been removed,

… Suzanne Gildert, the co-founder and chief science officer of Vancouver-based robotics company Kindred. Since 2014, her company has been developing intelligent robots [emphasis mine] that can be taught by humans to perform automated tasks — for example, handling and sorting products in a warehouse.

The idea is that when one of Kindred’s robots encounters a scenario it can’t handle, a human pilot can take control. The human can see, feel and hear the same things the robot does, and the robot can learn from how the human pilot handles the problematic task.

This process, called teleoperation, is one way to fast-track learning by manually showing the robot examples of what its trainers want it to do. But it also poses a potential moral and ethical quandary that will only grow more serious as robots become more intelligent.

“That AI is also learning my values,” Gildert explained during a talk on robot ethics at the Singularity University Canada Summit in Toronto on Wednesday [Oct. 11, 2017]. “Everything — my mannerisms, my behaviours — is all going into the AI.”

At its worst, everything from algorithms used in the U.S. to sentence criminals to image-recognition software has been found to inherit the racist and sexist biases of the data on which it was trained.

But just as bad habits can be learned, good habits can be learned too. The question is, if you’re building a warehouse robot like Kindred is, is it more effective to train those robots’ algorithms to reflect the personalities and behaviours of the humans who will be working alongside it? Or do you try to blend all the data from all the humans who might eventually train Kindred robots around the world into something that reflects the best strengths of all?

I notice Gildert distinguishes her robots as “intelligent robots” and then focuses on AI and issues with bias which have already arisen with regard to algorithms (see my May 24, 2017 posting about bias in machine learning, AI, and .Note: if you’re in Vancouver on Oct. 26, 2017 and interested in algorithms and bias), there’s a talk being given by Dr. Cathy O’Neil, author the Weapons of Math Destruction, on the topic of Gender and Bias in Algorithms. It’s not free but  tickets are here.)

Final comments

There is one more aspect I want to mention. Even as someone who usually deals with nanobots, it’s easy to start discussing robots as if the humanoid ones are the only ones that exist. To recapitulate, there are humanoid robots, utilitarian robots, intelligent robots, AI, nanobots, ‘microscopic bots, and more all of which raise questions about ethics and social impacts.

However, there is one more category I want to add to this list: cyborgs. They live amongst us now. Anyone who’s had a hip or knee replacement or a pacemaker or a deep brain stimulator or other such implanted device qualifies as a cyborg. Increasingly too, prosthetics are being introduced and made part of the body. My April 24, 2017 posting features this story,

This Case Western Reserve University (CRWU) video accompanies a March 28, 2017 CRWU news release, (h/t ScienceDaily March 28, 2017 news item)

Bill Kochevar grabbed a mug of water, drew it to his lips and drank through the straw.

His motions were slow and deliberate, but then Kochevar hadn’t moved his right arm or hand for eight years.

And it took some practice to reach and grasp just by thinking about it.

Kochevar, who was paralyzed below his shoulders in a bicycling accident, is believed to be the first person with quadriplegia in the world to have arm and hand movements restored with the help of two temporarily implanted technologies. [emphasis mine]

A brain-computer interface with recording electrodes under his skull, and a functional electrical stimulation (FES) system* activating his arm and hand, reconnect his brain to paralyzed muscles.

Does a brain-computer interface have an effect on human brain and, if so, what might that be?

In any discussion (assuming there is funding for it) about ethics and social impact, we might want to invite the broadest range of people possible at an ‘earlyish’ stage (although we’re already pretty far down the ‘automation road’) stage or as Jack Stilgoe and Toby Walsh note, technological determinism holds sway.

Once again here are links for the articles and information mentioned in this double posting,

That’s it!

ETA Oct. 16, 2017: Well, I guess that wasn’t quite ‘it’. BBC’s (British Broadcasting Corporation) Magazine published a thoughtful Oct. 15, 2017 piece titled: Can we teach robots ethics?

Robots in Vancouver and in Canada (one of two)

This piece just started growing. It started with robot ethics, moved on to sexbots and news of an upcoming Canadian robotics roadmap. Then, it became a two-part posting with the robotics strategy (roadmap) moving to part two along with robots and popular culture and a further  exploration of robot and AI ethics issues..

What is a robot?

There are lots of robots, some are macroscale and others are at the micro and nanoscales (see my Sept. 22, 2017 posting for the latest nanobot). Here’s a definition from the Robot Wikipedia entry that covers all the scales. (Note: Links have been removed),

A robot is a machine—especially one programmable by a computer— capable of carrying out a complex series of actions automatically.[2] Robots can be guided by an external control device or the control may be embedded within. Robots may be constructed to take on human form but most robots are machines designed to perform a task with no regard to how they look.

Robots can be autonomous or semi-autonomous and range from humanoids such as Honda’s Advanced Step in Innovative Mobility (ASIMO) and TOSY’s TOSY Ping Pong Playing Robot (TOPIO) to industrial robots, medical operating robots, patient assist robots, dog therapy robots, collectively programmed swarm robots, UAV drones such as General Atomics MQ-1 Predator, and even microscopic nano robots. [emphasis mine] By mimicking a lifelike appearance or automating movements, a robot may convey a sense of intelligence or thought of its own.

We may think we’ve invented robots but the idea has been around for a very long time (from the Robot Wikipedia entry; Note: Links have been removed),

Many ancient mythologies, and most modern religions include artificial people, such as the mechanical servants built by the Greek god Hephaestus[18] (Vulcan to the Romans), the clay golems of Jewish legend and clay giants of Norse legend, and Galatea, the mythical statue of Pygmalion that came to life. Since circa 400 BC, myths of Crete include Talos, a man of bronze who guarded the Cretan island of Europa from pirates.

In ancient Greece, the Greek engineer Ctesibius (c. 270 BC) “applied a knowledge of pneumatics and hydraulics to produce the first organ and water clocks with moving figures.”[19][20] In the 4th century BC, the Greek mathematician Archytas of Tarentum postulated a mechanical steam-operated bird he called “The Pigeon”. Hero of Alexandria (10–70 AD), a Greek mathematician and inventor, created numerous user-configurable automated devices, and described machines powered by air pressure, steam and water.[21]

The 11th century Lokapannatti tells of how the Buddha’s relics were protected by mechanical robots (bhuta vahana yanta), from the kingdom of Roma visaya (Rome); until they were disarmed by King Ashoka. [22] [23]

In ancient China, the 3rd century text of the Lie Zi describes an account of humanoid automata, involving a much earlier encounter between Chinese emperor King Mu of Zhou and a mechanical engineer known as Yan Shi, an ‘artificer’. Yan Shi proudly presented the king with a life-size, human-shaped figure of his mechanical ‘handiwork’ made of leather, wood, and artificial organs.[14] There are also accounts of flying automata in the Han Fei Zi and other texts, which attributes the 5th century BC Mohist philosopher Mozi and his contemporary Lu Ban with the invention of artificial wooden birds (ma yuan) that could successfully fly.[17] In 1066, the Chinese inventor Su Song built a water clock in the form of a tower which featured mechanical figurines which chimed the hours.

The beginning of automata is associated with the invention of early Su Song’s astronomical clock tower featured mechanical figurines that chimed the hours.[24][25][26] His mechanism had a programmable drum machine with pegs (cams) that bumped into little levers that operated percussion instruments. The drummer could be made to play different rhythms and different drum patterns by moving the pegs to different locations.[26]

In Renaissance Italy, Leonardo da Vinci (1452–1519) sketched plans for a humanoid robot around 1495. Da Vinci’s notebooks, rediscovered in the 1950s, contained detailed drawings of a mechanical knight now known as Leonardo’s robot, able to sit up, wave its arms and move its head and jaw.[28] The design was probably based on anatomical research recorded in his Vitruvian Man. It is not known whether he attempted to build it.

In Japan, complex animal and human automata were built between the 17th to 19th centuries, with many described in the 18th century Karakuri zui (Illustrated Machinery, 1796). One such automaton was the karakuri ningyō, a mechanized puppet.[29] Different variations of the karakuri existed: the Butai karakuri, which were used in theatre, the Zashiki karakuri, which were small and used in homes, and the Dashi karakuri which were used in religious festivals, where the puppets were used to perform reenactments of traditional myths and legends.

The term robot was coined by a Czech writer (from the Robot Wikipedia entry; Note: Links have been removed)

‘Robot’ was first applied as a term for artificial automata in a 1920 play R.U.R. by the Czech writer, Karel Čapek. However, Josef Čapek was named by his brother Karel as the true inventor of the term robot.[6][7] The word ‘robot’ itself was not new, having been in Slavic language as robota (forced laborer), a term which classified those peasants obligated to compulsory service under the feudal system widespread in 19th century Europe (see: Robot Patent).[37][38] Čapek’s fictional story postulated the technological creation of artificial human bodies without souls, and the old theme of the feudal robota class eloquently fit the imagination of a new class of manufactured, artificial workers.

I’m particularly fascinated by how long humans have been imagining and creating robots.

Robot ethics in Vancouver

The Westender, has run what I believe is the first article by a local (Vancouver, Canada) mainstream media outlet on the topic of robots and ethics. Tessa Vikander’s Sept. 14, 2017 article highlights two local researchers, Ajung Moon and Mark Schmidt, and a local social media company’s (Hootsuite), analytics director, Nik Pai. Vikander opens her piece with an ethical dilemma (Note: Links have been removed),

Emma is 68, in poor health and an alcoholic who has been told by her doctor to stop drinking. She lives with a care robot, which helps her with household tasks.

Unable to fix herself a drink, she asks the robot to do it for her. What should the robot do? Would the answer be different if Emma owns the robot, or if she’s borrowing it from the hospital?

This is the type of hypothetical, ethical question that Ajung Moon, director of the Open Roboethics Initiative [ORI], is trying to answer.

According to an ORI study, half of respondents said ownership should make a difference, and half said it shouldn’t. With society so torn on the question, Moon is trying to figure out how engineers should be programming this type of robot.

A Vancouver resident, Moon is dedicating her life to helping those in the decision-chair make the right choice. The question of the care robot is but one ethical dilemma in the quickly advancing world of artificial intelligence.

At the most sensationalist end of the scale, one form of AI that’s recently made headlines is the sex robot, which has a human-like appearance. A report from the Foundation for Responsible Robotics says that intimacy with sex robots could lead to greater social isolation [emphasis mine] because they desensitize people to the empathy learned through human interaction and mutually consenting relationships.

I’ll get back to the impact that robots might have on us in part two but first,

Sexbots, could they kill?

For more about sexbots in general, Alessandra Maldonado wrote an Aug. 10, 2017 article for salon.com about them (Note: A link has been removed),

Artificial intelligence has given people the ability to have conversations with machines like never before, such as speaking to Amazon’s personal assistant Alexa or asking Siri for directions on your iPhone. But now, one company has widened the scope of what it means to connect with a technological device and created a whole new breed of A.I. — specifically for sex-bots.

Abyss Creations has been in the business of making hyperrealistic dolls for 20 years, and by the end of 2017, they’ll unveil their newest product, an anatomically correct robotic sex toy. Matt McMullen, the company’s founder and CEO, explains the goal of sex robots is companionship, not only a physical partnership. “Imagine if you were completely lonely and you just wanted someone to talk to, and yes, someone to be intimate with,” he said in a video depicting the sculpting process of the dolls. “What is so wrong with that? It doesn’t hurt anybody.”

Maldonado also embedded this video into her piece,

A friend of mine described it as creepy. Specifically we were discussing why someone would want to programme ‘insecurity’ as a  desirable trait in a sexbot.

Marc Beaulieu’s concept of a desirable trait in a sexbot is one that won’t kill him according to his Sept. 25, 2017 article on Canadian Broadcasting News (CBC) online (Note: Links have been removed),

Harmony has a charming Scottish lilt, albeit a bit staccato and canny. Her eyes dart around the room, her chin dips as her eyebrows raise in coquettish fashion. Her face manages expressions that are impressively lifelike. That face comes in 31 different shapes and 5 skin tones, with or without freckles and it sticks to her cyber-skull with magnets. Just peel it off and switch it out at will. In fact, you can choose Harmony’s eye colour, body shape (in great detail) and change her hair too. Harmony, of course, is a sex bot. A very advanced one. How advanced is she? Well, if you have $12,332 CAD to put towards a talkative new home appliance, REALBOTIX says you could be having a “conversation” and relations with her come January. Happy New Year.

Caveat emptor though: one novel bonus feature you might also get with Harmony is her ability to eventually murder you in your sleep. And not because she wants to.

Dr Nick Patterson, faculty of Science Engineering and Built Technology at Deakin University in Australia is lending his voice to a slew of others warning us to slow down and be cautious as we steadily approach Westworldian levels of human verisimilitude with AI tech. Surprisingly, Patterson didn’t regurgitate the narrative we recognize from the popular sci-fi (increasingly non-fi actually) trope of a dystopian society’s futile resistance to a robocalypse. He doesn’t think Harmony will want to kill you. He thinks she’ll be hacked by a code savvy ne’er-do-well who’ll want to snuff you out instead. …

Embedded in Beaulieu’s article is another video of the same sexbot profiled earlier. Her programmer seems to have learned a thing or two (he no longer inputs any traits as you’re watching),

I guess you could get one for Christmas this year if you’re willing to wait for an early 2018 delivery and aren’t worried about hackers turning your sexbot into a killer. While the killer aspect might seem farfetched, it turns out it’s not the only sexbot/hacker issue.

Sexbots as spies

This Oct. 5, 2017 story by Karl Bode for Techdirt points out that sex toys that are ‘smart’ can easily be hacked for any reason including some mischief (Note: Links have been removed),

One “smart dildo” manufacturer was recently forced to shell out $3.75 million after it was caught collecting, err, “usage habits” of the company’s customers. According to the lawsuit, Standard Innovation’s We-Vibe vibrator collected sensitive data about customer usage, including “selected vibration settings,” the device’s battery life, and even the vibrator’s “temperature.” At no point did the company apparently think it was a good idea to clearly inform users of this data collection.

But security is also lacking elsewhere in the world of internet-connected sex toys. Alex Lomas of Pentest Partners recently took a look at the security in many internet-connected sex toys, and walked away arguably unimpressed. Using a Bluetooth “dongle” and antenna, Lomas drove around Berlin looking for openly accessible sex toys (he calls it “screwdriving,” in a riff off of wardriving). He subsequently found it’s relatively trivial to discover and hijack everything from vibrators to smart butt plugs — thanks to the way Bluetooth Low Energy (BLE) connectivity works:

“The only protection you have is that BLE devices will generally only pair with one device at a time, but range is limited and if the user walks out of range of their smartphone or the phone battery dies, the adult toy will become available for others to connect to without any authentication. I should say at this point that this is purely passive reconnaissance based on the BLE advertisements the device sends out – attempting to connect to the device and actually control it without consent is not something I or you should do. But now one could drive the Hush’s motor to full speed, and as long as the attacker remains connected over BLE and not the victim, there is no way they can stop the vibrations.”

Does that make you think twice about a sexbot?

Robots and artificial intelligence

Getting back to the Vikander article (Sept. 14, 2017), Moon or Vikander or both seem to have conflated artificial intelligence with robots in this section of the article,

As for the building blocks that have thrust these questions [care robot quandary mentioned earlier] into the spotlight, Moon explains that AI in its basic form is when a machine uses data sets or an algorithm to make a decision.

“It’s essentially a piece of output that either affects your decision, or replaces a particular decision, or supports you in making a decision.” With AI, we are delegating decision-making skills or thinking to a machine, she says.

Although we’re not currently surrounded by walking, talking, independently thinking robots, the use of AI [emphasis mine] in our daily lives has become widespread.

For Vikander, the conflation may have been due to concerns about maintaining her word count and for Moon, it may have been one of convenience or a consequence of how the jargon is evolving with ‘robot’ meaning a machine specifically or, sometimes, a machine with AI or AI only.

To be precise, not all robots have AI and not all AI is found in robots. It’s a distinction that may be more important for people developing robots and/or AI but it also seems to make a difference where funding is concerned. In a March 24, 2017 posting about the 2017 Canadian federal budget I noticed this,

… The Canadian Institute for Advanced Research will receive $93.7 million [emphasis mine] to “launch a Pan-Canadian Artificial Intelligence Strategy … (to) position Canada as a world-leading destination for companies seeking to invest in artificial intelligence and innovation.”

This brings me to a recent set of meetings held in Vancouver to devise a Canadian robotics roadmap, which suggests the robotics folks feel they need specific representation and funding.

See: part two for the rest.

Alan Copperman and Amanda Marcotte have a very US-centric discussion about CRISPR and germline editing (designer babies?)

For anyone who needs more information, I ran a three part series on CRISPR germline editing on August 15, 2017:

Part 1 opens the series with a basic description of CRISPR and the germline research that occasioned the series along with some of the ethical issues and patent disputes that are arising from this new technology. CRISPR and editing the germline in the US (part 1 of 3): In the beginning

Part 2 covers three critical responses to the reporting and between them describe the technology in more detail and the possibility of ‘designer babies’.  CRISPR and editing the germline in the US (part 2 of 3): ‘designer babies’?

Part 3 is all about public discussion or, rather, the lack of and need for according to a couple of social scientists. Informally, there is some discussion via pop culture and Joelle Renstrom notes although she is focused on the larger issues touched on by the television series, Orphan Black and as I touch on in my final comments. CRISPR and editing the germline in the US (part 3 of 3): public discussions and pop culture

The news about CRISPR and germline editing by a US team made a bit of a splash even being mentioned on Salon.com, which hardly ever covers any science news (except for some occasional climate change pieces). In a Sept. 4, 2017 salon.com item (an excerpt from the full interview) Amanda Marcotte talks with Dr. Alan Copperman director of the division of reproductive endocrinology and infertility at Mount Sinai Medical Center about the technology and its implications.  As noted in the headline, it’s a US-centric discussion where assumptions are made about who will be leading discussions about the future of the technology.

It’s been a while since I’ve watched it but I believe they do mention in passing that Chinese scientists published two studies about using CRISPR to edit the germline (i think there’s a third Chinese paper in the pipeline) before the American team announced its accomplishment in August 2017. By the way, the first paper by the Chinese caused quite the quandary in April 2015. (My May 14, 2015 posting covers some of the ethical issues; scroll down about 50% of the way for more about the impact of the published Chinese research.)

Also, you might want notice just how smooth Copperman’s responses are almost always emphasizing the benefits of the technology before usually answering the question. He’s had media training and he’s good at this.

They also talk about corn and CRISPR just about the time that agricultural research was announced. Interesting timing, non? (See my Oct. 11, 2017 posting about CRISPR edited corn coming to market in 2020.)

For anyone who wants to skip to the full Marcotte/Cooperman interview, go here on Facebook.