Posts Tagged ‘Arizona State University’

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The importance of science fiction for the future

Tuesday, May 7th, 2013

I started this post in March (2013) but haven’t had time till now (May 7, 2013) to flesh it out. It was a Mar. 28, 2013 posting by Jessica Bland and Lydia Nicholas for the UK Guardian science blogs which inspired me (Note: Links have been removed),

Science fiction and real-world innovation have always fed off each other. The history of the electronic book shows us things are more complicated than fiction predicting fact [.]

…

Imagine a new future. No, not that tired old vision of hoverboards and robot butlers: something really new and truly strange. It’s hard. It’s harder still to invent the new things that will fill this entirely new world. New ideas that do not fit or that come from unfamiliar places are often ignored. Hedy Lemarr [a major movie sex symbol in her day] and George Antheil’s [musician] frequency-hopping patent was ignored for 20 years because the US Navy could not believe that Hollywood artists could invent a method of secure communication. Many of Nikola Tesla’s inventions and his passionate belief in the importance of renewable energy were ignored by a world that could not imagine a need for them.

Stories open our eyes to the opportunities and hazards of new technologies. By articulating our fears and desires for the future, stories help shape what is to come – informing public debate, influencing regulation and inspiring inventors. And this makes it important that we do not just listen to the loudest voices.

Of course it isn’t as simple as mining mountains of pulp sci-fi for the schematics of the next rocket or the algorithms of the next Google. Arthur C. Clarke, often attributed with the invention of the communication satellite, firmly believed that these satellites would require crews. The pervasive connectivity that defines our world today would never have existed if every satellite needed to be manned.

The Guardian posting was occasioned by the publication of two research papers produced for NESTA. It’s an organization which is not similar to any in Canada or the US (as far as I know). Here’s a little more about NESTA from their FAQs page,

Nesta is an independent charity with a mission to help people and organisations bring great ideas to life. We do this by providing investments and grants and mobilising research, networks and skills.

Nesta backs innovation to help bring great ideas to life. We do this by providing investments and grants and mobilising research, networks and skills.

Nesta receives funds from The Nesta Trust, which received the National Lottery endowment from the National Endowment for Science, Technology and the Arts.

The interest from this endowment is used to fund our activities. These activities must be used to promote the charitable objects of both the Nesta Trust and the Nesta charity. We also use the returns from Nesta investments, and income from working in partnership with others, to fund our work.

We don’t receive any ongoing general government funds to support our work.

On 1st April 2012 Nesta ceased being a Non-Departmental Public Body (NDPB) and became a charity (charity number 1144091).

We maintain our mission to carry out research into innovation and to further education, science, technology, the arts, public services, the voluntary sector and enterprise in various areas by encouraging and supporting innovation.

Nesta’s objectives are now set out in our ‘charitable objects’ which can be viewed here.

Nesta continues to operate at no cost to the Government or the taxpayer using return from the Nesta Trust.

In any event, NESTA commissioned two papers:

Imagining technology
Jon Turney
Nesta Working Paper 13/06
Issued: March 2013

Better Made Up: The Mutual Influence of Science fiction and Innovation
Caroline Bassett, Ed Steinmueller, Georgina Voss
Nesta Working Paper 13/07
Issued: March 2013

For anyone who does not have time to read the NESTA papers, the Guardian’s post by Bland and Nicholas provides a good overview of the thinking which links science fiction with real innovation.

Around the same time I stumbled across the Bland/Nicholas post I also stumbled on a science fiction conference that is regularly held at the University of California Riverside.

The Eaton Science Fiction Conference was held Apr. 11 – 14, 2013 and the theme was “Science Fiction Media. It’s a little late for this year but perhaps you want to start planning for next year.  Here’s the Eaton Science Fiction Conference website. For those who’d like to get a feel for this conference, here’s a little more from the Mar. 27, 2013 news release by Bettye Miller,

… the 2013 conference will be largest in the 34-year history of the conference, said Melissa Conway, head of Special Collections and Archives of the UCR Libraries and conference co-organizer. It also is the first time the UCR Libraries and College of Humanities, Arts and Social Sciences have partnered with the Science Fiction Research Association, the largest and most prestigious scholarly organization in the field, to present the event.

…

Among the science fiction writers who will be presenting on different panels are: Larry Niven, author of “Ringworld” and a five-time winner of the Hugo Award and a Nebula; Gregory Benford, astrophysicist and winner of a Nebula Award and a United Nations Medal in Literature; David Brin, astrophysicist and two-time winner of the Hugo Award; Audre Bormanis, writer/producer for “Star Trek: Enterprise,” “Threshold,” “Eleventh Hour,” “Legend of the Seeker” and “Tron: Uprising”; Kevin Grazier, science adviser for “Battlestar Galactica,” “Defiance,” “Eureka” and “Falling Skies”; and James Gunn, winner of a Hugo Award and the 2007 Damon Knight Memorial Grand Master, presented for lifetime achievement as a writer of science fiction and/or fantasy by the Science Fiction and Fantasy Writers of America.

As for the impetus for this conference in Riverside, California, from the news release,

UCR is the home of the Eaton Collection of Science Fiction and Fantasy, the largest publicly accessible collection of its kind in the world. The collection embraces every branch of science fiction, fantasy, horror and utopian/dystopian fiction.

The collection, which attracts scholars from around the world, holds more than 300,000 items including English-language science fiction, fantasy and horror published in the 20th century and a wide range of works in Spanish, French, Russian, Chinese, Japanese, German, and a dozen other languages; fanzines; comic books; anime; manga; science fiction films and television series; shooting scripts; archives of science fiction writers; and science fiction collectibles and memorabilia.

In one of those odd coincidences we all experience from time to time, Ray Harryhausen, creator of a type of stop-motion model animation known as Dynamation and well loved for his work in special effects and who was recognized with a life time achievement at the 2013 conference, died today (May 7, 2013; Wikipedia essay).

The item which moved me to publish today (May 7, 2013), Can Science Fiction Writers Inspire The World To Save Itself?, by Ariel Schwartz concerns the Hieroglyph project at Arizona State University,

Humanity’s lack of a positive vision for the future can be blamed in part on an engineering culture that’s more focused on incrementalism (and VC funding) than big ideas. But maybe science fiction writers should share some of the blame. That’s the idea that came out of a conversation in 2011 between science fiction author Neal Stephenson and Michael Crow, the president of Arizona State University.

…

If science fiction inspires scientists and engineers to create new things–Stephenson believes it can–then more visionary, realistic sci-fi stories can help create a better future. Hence the Hieroglyph experiment, launched this month as a collaborative website for researchers and writers. Many of the stories created on the platform will go into a HarperCollins anthology of fiction and non-fiction, set to be published in 2014.

Here’s more about the Hieroglyph project from the About page,

Inspiration is a small but essential part of innovation, and science fiction stories have been a seminal source of inspiration for innovators over many decades. In his article entitled “Innovation Starvation,” Neal Stephenson calls for a return to inspiration in contemporary science fiction. That call resonated with so many and so deeply that Project Hieroglyph was born shortly thereafter.

The name of Project Hieroglyph comes from the notion that certain iconic inventions in science fiction stories serve as modern “hieroglyphs” – Arthur Clarke’s communications satellite, Robert Heinlein’s rocket ship that lands on its fins, Issac Asimov’s robot, and so on. Jim Karkanias of Microsoft Research described hieroglyphs as simple, recognizable symbols on whose significance everyone agrees.

…

While the mission of Project Hieroglyph begins with creative inspiration, our hope is that many of us will be genuinely inspired towards realization.

This project is an initiative of Arizona State University’s Center for Science and Imagination.

It’s great seeing this confluence of thinking about science fiction, innovation, and science. I’m pretty sure we knew this in the 19th century (and probably before that too) and I just hope we don’t forget it again.

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A twist in my DNA

Friday, March 22nd, 2013

Professor Hao Yan’s team at Arizona State University (ASU) has created some new 2D and 3D DNA objects according to a Mar. 21, 2013 news release on EurekAlert,

In their latest twist to the technology, Yan’s team made new 2-D and 3-D objects that look like wire-frame art of spheres as well as molecular tweezers, scissors, a screw, hand fan, and even a spider web.

The Yan lab, which includes ASU Biodesign Institute colleagues Dongran Han, Suchetan Pal, Shuoxing Jiang, Jeanette Nangreave and assistant professor Yan Liu, published their results in the March 22 issue of Science.

Here’s where the twist comes in,

The twist in their ‘bottom up,’ molecular Lego design strategy focuses on a DNA structure called a Holliday junction. In nature, this cross-shaped, double-stacked DNA structure is like the 4-way traffic stop of genetics — where 2 separate DNA helices temporality meet to exchange genetic information. The Holliday junction is the crossroads responsible for the diversity of life on Earth, and ensures that children are given a unique shuffling of traits from a mother and father’s DNA.

In nature, the Holliday junction twists the double-stacked strands of DNA at an angle of about 60-degrees, which is perfect for swapping genes but sometimes frustrating for DNA nanotechnology scientists, because it limits the design rules of their structures.

“In principal, you can use the scaffold to connect multiple layers horizontally,” [which many research teams have utilized since the development of DNA origami by Cal Tech's Paul Rothemund in 2006]. However, when you go in the vertical direction, the polarity of DNA prevents you from making multiple layers,” said Yan. “What we needed to do is rotate the angle and force it to connect.”

Making the new structures that Yan envisioned required re-engineering the Holliday junction by flipping and rotating around the junction point about half a clock face, or 150 degrees. Such a feat has not been considered in existing designs.

“The initial idea was the hardest part,” said Yan. “Your mind doesn’t always see the possibilities so you forget about it. We had to break the conceptual barrier that this could happen.”

In the new study, by varying the length of the DNA between each Holliday junction, they could force the geometry at the Holliday junctions into an unconventional rearrangement, making the junctions more flexible to build for the first time in the vertical dimension. Yan calls the backyard barbeque grill-shaped structure a DNA Gridiron.

“We were amazed that it worked!” said Yan. “Once we saw that it actually worked, it was relatively easy to implement new designs. Now it seems easy in hindsight. If your mindset is limited by the conventional rules, it’s really hard to take the next step. Once you take that step, it becomes so obvious.”

The DNA Gridiron designs are programmed into a viral DNA, where a spaghetti-shaped single strand of DNA is spit out and folded together with the help of small ‘staple’ strands of DNA that help mold the final DNA structure. In a test tube, the mixture is heated, then rapidly cooled, and everything self-assembles and molds into the final shape once cooled. Next, using sophisticated AFM and TEM imaging technology, they are able to examine the shapes and sizes of the final products and determine that they had formed correctly.

This approach has allowed them to build multilayered, 3-D structures and curved objects for new applications.

In addition to the EurekAlert version, you can find the full text, images, and video about the team’s paper in the Mar. 21, 2013 news item on ScienceDaily (a citation and link to the team’s paper is also included) or you can read the original Mar. 21, 2013 ASU news release. (Hao Yan’s work was last mentioned here in an Aug. 7, 2012 post.)

All of this talk of twists reminded me of a song by Tanita Tikaram, Twist in My Sobriety. I found this video of an acoustic performance (two guitars and a bass [the musical instrument not the fish]) which is even more sultry than original hit version,

Happy weekend!

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Precision delivery of synthetic vaccines using DNA scaffolds

Tuesday, August 7th, 2012

When reading about nanomedicine, one is struck by the focus on precision especially with the regard to drug delivery and other therapeutics. There’s almost always a reference to repairing or destroying  malfunctioning/diseased tissue or cells to the exclusion of the  healthy tissues/cells.

The latest work from Arizona State University has raised a great deal of interest not just with this latest announcement but also some previous work. From the July 27, 2012 posting by Dexter Johnson on his Nanoclast blog on the IEEE [Institute for Electrical and Electronics Engineers],

About 18 months ago, the nanotech trade press was buzzing with the work of Hongbin Yu and Hao Yan, both from Arizona State University (ASU), when they developed a method that used DNA origami as a scaffold. When the DNA scaffolding was combined with “nano islands” made from gold, it enabled the manufacturing of smaller electronic memory devices.

Now [July 2012] Yan has joined with Yung Chang, a biodesign immunologist also from ASU, to use three-dimensional DNA structures as a scaffold on which they piggybacked synthetic vaccine complexes to make the delivery of the vaccines safer and more effective.

There are more details in the July 25, 2012 news item on ScienceDaily,

DNA nanotechnology, where the molecule of life can be assembled into 2-D and 3-D shapes, has an advantage of being a programmable system that can precisely organize molecules to mimic the actions of natural molecules in the body.

“We wanted to test several different sizes and shapes of DNA nanostructures and attach molecules to them to see if they could trigger an immune response,” said Yan, the Milton D. Glick Distinguished Chair in the Department of Chemistry and Biochemistry and researcher in Biodesign’s Center for Single Molecule Biophysics. With their biomimicry approach, the vaccine complexes they tested closely resembled natural viral particles in size and shape.

As proof of concept, they tethered onto separate pyramid-shaped and branched DNA structures a model immune stimulating protein called streptavidin (STV) and immune response boosting compound called an adjuvant (CpG oligo-deoxynucletides) to make their synthetic vaccine complexes.

First, the group had to prove that the target cells could gobble the nanostructures up. By attaching a light-emitting tracer molecule to the nanostructures, they found the nanostructures residing comfortably within the appropriate compartment of the cells and stable for several hours — -long enough to set in motion an immune cascade.

Next, in a mouse challenge, they targeted the delivery of their vaccine cargo to cells that are first responders in initiating an effective immune response, coordinating interaction of important components, such as: antigen presenting cells, including macrophages, dendritic cells and B cells. After the cargo is internalized in the cell, they are processed and “displayed” on the cell surface to T cells, white blood cells that play a central role in triggering a protective immune response. The T cells, in turn, assist B cells with producing antibodies against a target antigen.

To properly test all variables, they injected: 1) the full vaccine complex 2) STV (antigen) alone 3) the CpG (adjuvant) mixed with STV.

Over the course of 70 days, the group found that mice immunized with the full vaccine complex developed a more robust immune response up to 9-fold higher than the CpG mixed with STV. The pyramid (tetrahedral) shaped structure generated the greatest immune response. Not only was immune response to the vaccine complex specific and effective, but also safe, as the research team showed, using two independent methods, that no immune response triggered from introducing the DNA platform alone.

Here’s a little background information that may help to explain why researchers are looking for new ways to deliver vaccines, from the July 30, 2012 essay by Carl Walkey (University of Toronto) for the Nanowerk Spotlight series,

Traditionally, vaccines were formulated using attenuated or inactivated versions of the microbes they were intended to treat. However, inactivated microbes do not often elicit a strong enough immune response to induce antibody production. Attenuated viruses, on the other hand, may revert back to an active form within the body. There are also inherent difficulties in ensuring batch-to-batch consistency of the formulations. These shortcomings have led to a progressive shift towards the development of synthetic vaccines.

Synthetic vaccines can combine a portion of the target microbe, known as an ‘antigen’ together with an adjuvant that stimulates the immune system. They are more reproducible and have the potential to induce consistent and tailored immune responses. Yet, delivering both the adjuvant and antigen together to the appropriate immune cells is challenging.

While the developments at Arizona State University are exciting, it’s still a long way before there will be any treatments, from the Walkey essay,

Although the results from this study are encouraging, they represent only a step towards the ultimate goal of making DNA nanostructure-based vaccines a clinical reality. There are still many challenges.

“A big challenge from an immunological point of view is the stability of the particles” explains Chang. The body is equipped with an array of ‘nucleases’ – enzymes designed to degrade extracellular DNA. Nucleases may degrade the nanostructures before they reach their target.”

“I think safety will also be a major hurdle for the eventual clinical translation” he continues. “That will be the major concern people will have. It may cause an adverse effect or an auto-immune response. Those are the things we need to test thoroughly before moving into clinical trials.”

The researchers believe that the simplicity, robustness, and relative economy of the DNA nanostructures will be key advantages driving further development.

“DNA nanostructures have the advantage of self-assembling. You can produce them relatively simply with good reproducibility” says Yan. “With so many of the other nanoparticle systems, you have to synthesize different components chemically. This makes them difficult to scale-up.”

The July 24, 2012 news release from Arizona State University offers this comment on the potential,

Overall, though the field of DNA is still young, the research is advancing at a breakneck pace toward translational science that is making an impact on health care, electronics, and other applications.

While Chang and Yan agree that there is still much room to explore the manipulation and optimization of the nanotechnology, it also holds great promise.  “With this proof of concept, the range of antigens that we could use for synthetic vaccine develop is really unlimited,” said Chang.

I like the idea of more precise delivery of drugs and other therapies. Intuitively, it just makes sense that you want to focus on the diseased or destroyed tissues while preserving as much of the healthy ones as possible but I keep wondering if there might be a more subtle disease process at work. The problem may not lie in the diseased cells or tissues themselves but may originate in an entirely different part of the body. If you ever watch someone who’s walking awkwardly, you may notice the problem isn’t the foot placement; the real problem is in the hips. You are in fact examining the symptom rather than the problem. In which case, more precise application of various therapies will alleviate symptoms for a time while the disease process carries on.

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Design, architechture, biomimicry, and a transdisciplinary project in the tropics

Thursday, January 26th, 2012

Getting a design project on the scale of developing a research station for the US Smithsonian Institute’s only research facility outside the US has got to be a thrill—especially if you’re a student looking for experience and résumé-building credits. Students from Arizona State University (ASU) got exactly that opportunity. From the Jan. 13, 2012 news release at ASU,

The graduate students [six teams of students from ASU’s Herberger Institute for Design and the Arts and the School of Life Sciences] are partners in the traveling studio program developed by The Design School at ASU, which journeyed to Gamboa, Panama, to collaborate with the program’s partner, the Smithsonian Tropical Research Institute.

…

The students’ assignment was to create biomimetic architectural and product-design concepts for a scientific field station on the Gigante Peninsula, a remote spit of land located in the Panama Canal Zone.

Here’s an ASU video of the instructors and students discussing the trip and showing off some of the design concepts,

ASU biologists and designers showcase biomimetic solutions for Smithsonian from ASU News on Vimeo.

ASU is hosting an exhibition of the students’ design concepts (posters) from Jan. 24 – Feb. 9, 2012. You can get more information about that here.

For anyone who’s not able to visit the exhibition and get more details, here’s information about some of the limitations the students were dealing with (from the news release),

The challenge of designing permanent structures on the Gigante Peninsula in Panama tests architects on multiple fronts, says White [Philip White, associate professor and ecological design strategist whose focus, besides teaching, is the development of ecologically intelligent products and systems]. Buildings are subject to insect infestations and periodic flooding. Obtaining sunlight for solar power and room lighting, as well as capturing cross breezes for natural cooling, requires destructive cutting of openings in the forest canopy. Such design challenges are what engaged architectural student Adam Tate’s interest. Tate developed plans [featured in the video] for a mobile research laboratory built on a floating pontoon structure, with joints and springs modeled after elements of the trap-jaw ant.

The exhibit will showcase Tate’s design, along with a backpack inspired by the musculoskeletal structure of the three-toed sloth, an umbrella derived from bats, which will resist wind torsion, and a design for a photovoltaic canopy based on lobster eyes – perfect for the challenges of the low light environment of the jungle.

This is not the only biomimicry project at ASU (from the news release),

Scientists at ASU have been using concepts of biomimicry in various studies across the campuses. For example, Ana Moore and Thomas Moore, both Regents’ Professors at ASU in the Department of Chemistry and Biochemistry, have work that is funded by the National Science Foundation to use bio-inspired approaches to improve solar energy conversion. One of their projects is a photovoltaic cell that utilizes design concepts drawn from photosynthesis in leaves. Scientists Jeff Yarger and Gregory Holland also are deconstructing the molecular makeup of spider silk hoping to create stronger, light-weight materials, such as bulletproof vests and artificial tendons.

I hope one day to see some these designs taken from concept to product.

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It’s a bird. It’s a plane. No, it’s a laser!

Friday, October 14th, 2011

I couldn’t resist the Superman reference although it really should have been a Morpho butterfly or a jewel beetle reference since these are two other animals/insects that also display unusual optical properties courtesy of nanoscale structures.

Top: Male eastern bluebird (Sialia sialis, Turdidae). Credit: Ken Thomas (image in public domain). Published in Soft Matter, 2009, 5, 1792-1795. E.R. Dufresne et al., “Self-assembly of amorphous biophotonic nanostructures by phase separation.” Royal Society of Chemistry. http://dx.doi.org/10.1039/B902775K

According to the Oct. 12, 2011 news item on Nanowerk,

Researchers at Yale University are studying how two types of nanoscale structures on the feathers of birds produce brilliant and distinctive colors. The researchers are hoping that by borrowing these nanoscale tricks from nature they will be able to produce new types of lasers—ones that can assemble themselves by natural processes. The team will present their findings at the Optical Society’s (OSA) Annual Meeting, Frontiers in Optics (FiO) 2011, taking place in San Jose, Calif. next week. [It starts Sunday, Oct. 16, 2011.]

Devin Powell, in a May 13, 2011 article for Science News provides some additional detail,

The barbs of these feathers [from bluebirds, blue jays, and parrots] contain tiny pockets of air. Light striking the tightly packed air bubbles scatters, bringing out deep shades of blues and ultraviolet (which birds can see but humans can’t).

“Birds use these structures to create colors that they can’t make in other ways,” says Richard Prum, an  ornithologist at Yale University who discovered the mechanism behind this color.

To make a two-dimensional imitation of a bird feather, Yale physicist Hui Cao and her colleagues punched holes into a thin slice of gallium arsenide semiconductor. The holes were arranged like people in a crowd — somewhat haphazardly but with small-scale patterns that dictate roughly how far each hole is from its neighbor.

“The lesson we learned from nature is that we don’t need something perfect to get control,” says Cao, whose team describes their laser in the May 6 [2011] Physical Review Letters.

The latest work being presented is described this way in an Oct. 2011 news release (why aren’t people putting dates on their news releases????) from the Optical Society of America,

Inspired by feathers, the Yale physicists created two lasers that use this short-range order to control light. One model is based on feathers with tiny spherical air cavities packed in a protein called beta-keratin. The laser based on this model consists of a semiconductor membrane full of tiny air holes that trap light at certain frequencies. Quantum dots embedded between the holes amplify the light and produce the coherent beam that is the hallmark of a laser. The researchers also built a network laser using a series of interconnecting nano-channels, based on their observations of feathers whose beta-keratin takes the form of interconnecting channels in “tortuous and twisting forms.” The network laser produces its emission by blocking certain colors of light while allowing others to propagate. In both cases, researchers can manipulate the lasers’ colors by changing the width of the nano-channels or the spacing between the nano-holes.

What makes these short-range-ordered, bio-inspired structures different from traditional lasers is that, in principle, they can self-assemble, through natural processes similar to the formation of gas bubbles in a liquid. This means that engineers would not have to worry about the nanofabrication of the large-scale structure of the materials they design, resulting in cheaper, faster, and easier production of lasers and light-emitting devices.

Here’s an image of a ‘feather-based laser’,

Top: A laser based on feathers with the sphere-type nanostructure. This laser consists of tiny air holes (black) in a semiconductor membrane; each hole is about 77 nanometers across. (Scale bar = 5 micrometers.) Credit: Hui Cao Research Laboratory / Yale University.

As for the Morpho butterfly and jewel beetle, I last posted about gaining inspiration from these insects (biomimicry) in my May 20, 2011 posting in the context of some anti-counterfeiting strategies.

I first came across some of this work on the optical properties of nanostructures in nature in a notice about a 2008 conference on iridescence at Arizona State University. Here’s the stated purpose for the conference (from the conference page),

A unique, integrative 4–day conference on iridescent colors in nature, Iridescence: More than Meets the Eye is a graduate student proposed and organized conference supported by the Frontiers in Life Sciences program in Arizona State University’s School of Life Sciences. This conference intends to connect diverse groups of researchers to catalyze synthetic cross–disciplinary discussions regarding iridescent coloration in nature, identify new avenues of research, and explore the potential for these stunning natural phenomena to provide novel insights in fields as divergent as materials science, sexual selection and primary science education.

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From the bleeding edge to the cutting edge to ubiquitous? The PaperPhone, an innovation case study in progress

Thursday, May 12th, 2011

This story has it all: military, patents, international competition and cooperation, sex (well, not according to the academics but I think it’s possible), and a bizarre device – the PaperPhone (last mentioned in my May 6, 2011 posting on Human-Computer Interfaces).

“If you want to know what technologies people will be using 10 years in the future, talk to the people who’ve been working on a lab project for 10 years,” said Dr. Roel Vertegaal, Director of the Human Media Lab at Queen’s University in Kingston, Ontario. By the way, 10 years is roughly the length of time Vertegaal and his team have been working on a flexible/bendable phone/computer and he believes that it will be another five to 10 years before the device is available commercially.

Image from Human Media Lab press kit

As you can see in the image, the prototype device looks like a thin piece of plastic that displays a menu. In real life that black bit to the left of the image is the head of a cable with many wires connecting it to a computer. Here’s a physical description of the device copied from the paper (PaperPhone: Understanding the Use of Bend Gestures in Mobile Devices with Flexible Electronic Paper Displays) written by Byron Lahey, Audrey Girouard, Winslow Burleson and Vertegaal,

PaperPhone consists of an Arizona State University Flexible Display Center 3.7” Bloodhound flexible electrophoretic display, augmented with a layer of 5 Flexpoint 2” bidirectional bend sensors. The prototype is driven by an E Ink Broadsheet AM 300 Kit featuring a Gumstix processor. The prototype has a refresh rate of 780 ms for a typical full screen gray scale image.

An Arduino microcontroller obtains data from the Flexpoint bend sensors at a frequency of 20 Hz. Figure 2 shows the back of the display, with the bend sensor configuration mounted on a flexible printed circuit (FPC) of our own design. We built the FPC by printing its design on DuPont Pyralux flexible circuit material with a solid ink printer, then etching the result to obtain a fully functional flexible circuit substrate. PaperPhone is not fully wireless. This is because of the supporting rigid electronics that are required to drive the display. A single, thin cable bundle connects the AM300 and Arduino hardware to the display and sensors. This design maximizes the flexibility and mobility of the display, while keeping its weight to a minimum. The AM300 and Arduino are connected to a laptop running a Max 5 patch that processes sensor data, performs bend gesture recognition and sends images to the display. p. 3

It may look ungainly but it represents a significant step forward for the technology as this team (composed of researchers from Queen’s University, Arizona State University, and E Ink Corporation) appears to have produced the only working prototype in the world for a personal portable flexible device that will let you make phone calls, play music, read a book, and more by bending it. As they continue to develop the product, the device will become wireless.

The PaperPhone and the research about ‘bending’, i.e., the kinds of bending gestures people would find easiest and most intuitive to use when activating the device, were presented in Vancouver in an early session at the CHI 2011 Conference where I got a chance to speak to Dr. Vertegaal and his team.

Amongst other nuggets, I found out the US Department of Defense (not DARPA [Defense Advanced Research Projects Agency] oddly enough) has provided funding for the project. Military interest is focused on the device’s low energy requirements, lowlight screen, and light weight in addition to its potential ability to be folded up and carried like a piece of paper (i. e., it could mould itself to fit a number of tight spaces) as opposed to the rigid, ungiving borders of a standard mobile device. Of course, all of these factors are quite attractive to consumers too.

As is imperative these days, the ‘bends’ that activate the device have been patented and Vertegaal is in the process of developing a startup company that will bring this device and others to market. Queen’s University has an ‘industrial transfer’ office (they probably call it something else) which is assisting him with the startup.

There is international interest in the PaperPhone that is collaborative and competitive. Vertegaal’s team at Queen’s is partnered with a team at Arizona State University led by Dr. Winslow Burleson, professor in the Computer Systems Engineering and the Arts, Media, and Engineering graduate program and with Michael McCreary, Vice President Research & Development of E Ink Corporation representing an industry partner.

On the competitive side of things, the UK’s University of Cambridge and the Finnish Nokia Research Centre have been working on the Morph which as I noted in my May 6, 2011 posting still seems to be more concept than project.

Vertegaal noted that the idea of a flexible screen is not new and that North American companies have gone bankrupt trying to bring the screens to market. These days, you have to go to Taiwan for industrial production of flexible screens such as the PaperPhone’s.

One of my last questions to the team was about pornography. (In the early days of the Internet [which had its origins in military research], there were only two industries that made money online, pornography and gambling. The gambling opportunities seem pretty similar to what we already enjoy.) After an amused response, the consensus was that like gambling it’s highly unlikely a flexible phone could lend itself to anything new in the field of pornography. Personally, I’m not convinced about that one.

So there you have a case study for innovation. Work considered bleeding edge 10 years ago is now cutting edge and, in the next five to 10 years, that work will be become a consumer product. Along the way you have military investment, international collaboration and competition, failure and success, and, possibly, sex.

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Human-Computer interfaces: flying with thoughtpower, reading minds, and wrapping a telephone around your wrist

Friday, May 6th, 2011

This time I’ve decided to explore a few of the human/computer interface stories I’ve run across lately. So this posting is largely speculative and rambling as I’m not driving towards a conclusion.

My first item is a May 3, 2011 news item on physorg.com. It concerns an art installation at Rensselaer Polytechnic Institute, The Ascent. From the news item,

A team of Rensselaer Polytechnic Institute students has created a system that pairs an EEG headset with a 3-D theatrical flying harness, allowing users to “fly” by controlling their thoughts. The “Infinity Simulator” will make its debut with an art installation [The Ascent] in which participants rise into the air – and trigger light, sound, and video effects – by calming their thoughts.

I found a video of someone demonstrating this project:
http://blog.makezine.com/archive/2011/03/eeg-controlled-wire-flight.html

Please do watch:

I’ve seen this a few times and it still absolutely blows me away.

If you should be near Rensselaer on May 12, 2011, you could have a chance to fly using your own thoughtpower, a harness, and an EEG helmet. From the event webpage,

Come ride The Ascent, a playful mash-up of theatrics, gaming and mind-control. The Ascent is a live-action, theatrical ride experience created for almost anyone to try. Individual riders wear an EEG headset, which reads brainwaves, along with a waist harness, and by marshaling their calm, focus, and concentration, try to levitate themselves thirty feet into the air as a small audience watches from below. The experience is full of obstacles-as a rider ascends via the power of concentration, sound and light also respond to brain activity, creating a storm of stimuli that conspires to distract the rider from achieving the goal: levitating into “transcendence.” The paradox is that in order to succeed, you need to release your desire for achievement, and contend with what might be the biggest obstacle: yourself.

Theater Artist and Experience Designer Yehuda Duenyas (XXXY) presents his MFA Thesis project The Ascent, and its operating platform the Infinity System, a new user driven experience created specifically for EMPAC’s automated rigging system.

The Infinity System is a new platform and user interface for 3D flying which combines aspects of thrill-ride, live-action video game, and interactive installation.

Using a unique and intuitive interface, the Infinity System uses 3D rigging to move bodies creatively through space, while employing wearable sensors to manipulate audio and visual content.

Like a live-action stunt-show crossed with a video game, the user is given the superhuman ability to safely and freely fly, leap, bound, flip, run up walls, fall from great heights, swoop, buzz, drop, soar, and otherwise creatively defy gravity.

“The effect is nothing short of movie magic.” – Sean Hollister, Engadget

Here’s a brief description of the technology behind this ‘Ascent’ (from the news item on physorg.com),

Ten computer programs running simultaneously link the commercially available EEG headset to the computer-controlled 3-D flying harness and various theater systems, said Todd. [Michael Todd, a Rensselaer 2010 graduate in computer science]

Within the theater, the rigging – including the harness – is controlled by a Stage Tech NOMAD console; lights are controlled by an ION console running MIDI show control; sound through MAX/MSP; and video through Isadora and Jitter. The “Infinity Simulator,” a series of three C programs written by Todd, acts as intermediary between the headset and the theater systems, connecting and conveying all input and output.

“We’ve built a software system on top of the rigging control board and now have control of it through an iPad, and since we have the iPad control, we can have anything control it,” said Duenyas. “The ‘Infinity Simulator’ is the center; everything talks to the ‘Infinity Simulator.’”

This May 3, 2011 article (Mystery Man Gives Mind-Reading Tech More Early Cash Than Facebook, Google Combined) by Kit Eaton on Fast Company also concerns itself with a brain/computer interface. From the article,

Imagine the money that could be made by a drug company that accurately predicted and treated the onset of Alzheimer’s before any symptoms surfaced. That may give us an idea why NeuroVigil, a company specializing in non-invasive, wireless brain-recording tech, just got a cash injection that puts it at a valuation “twice the combined seed valuations of Google’s and Facebook’s first rounds,” according to a company announcement
…
NeuroVigil’s key product at the moment is the iBrain, a slim device in a flexible head-cap that’s designed to be worn for continuous EEG monitoring of a patient’s brain function–mainly during sleep. It’s non-invasive, and replaces older technology that could only access these kind of brain functions via critically implanted electrodes actually on the brain itself. The idea is, first, to record how brain function changes over time, perhaps as a particular combination of drugs is administered or to help diagnose particular brain pathologies–such as epilepsy.
…
But the other half of the potentailly lucrative equation is the ability to analyze the trove of data coming from iBrain. And that’s where NeuroVigil’s SPEARS algorithm enters the picture. Not only is the company simplifying collection of brain data with a device that can be relatively comfortably worn during all sorts of tasks–sleeping, driving, watching advertising–but the combination of iBrain and SPEARS multiplies the efficiency of data analysis [emphasis mine].

I assume it’s the notion of combining the two technologies (iBrian and SPEARS) that spawned the ‘mind-reading’ part of this article’s title. The technology could be used for early detection and diagnosis, as well as, other possibilities as Eaton notes,

It’s also possible it could develop its technology into non-medicinal uses such as human-computer interfaces–in an earlier announcement, NeuroVigil noted, “We plan to make these kinds of devices available to the transportation industry, biofeedback, and defense. Applications regarding pandemics and bioterrorism are being considered but cannot be shared in this format.” And there’s even a popular line of kid’s toys that use an essentially similar technique, powered by NeuroSky sensors–themselves destined for future uses as games console controllers or even input devices for computers.

What these two technologies have in common is that, in some fashion or other, they have (shy of implanting a computer chip) a relatively direct interface with our brains, which means (to me anyway) a very different relationship between humans and computers.

In the next couple of items I’m going to profile a couple of very similar to each other technologies that allow for more traditional human/computer interactions, one of which I’ve posted about previously, the Nokia Morph (most recently in my Sept. 29, 2010 posting).

It was first introduced as a type of flexible phone with other capabilities. Since then, they seem to have elaborated on those capabilities. Here’s a description of what they now call the ‘Morph concept’ in a [ETA May 12, 2011: inserted correct link information] May 4, 2011 news item on Nanowerk,

Morph is a joint nanotechnology concept developed by Nokia Research Center (NRC) and the University of Cambridge (UK). Morph is a concept that demonstrates how future mobile devices might be stretchable and flexible, allowing the user to transform their mobile device into radically different shapes. It demonstrates the ultimate functionality that nanotechnology might be capable of delivering: flexible materials, transparent electronics and self-cleaning surfaces.

Morph, will act as a gateway. It will connect the user to the local environment as well as the global internet. It is an attentive device that adapts to the context – it shapes according to the context. The device can change its form from rigid to flexible and stretchable. Buttons of the user interface can grow up from a flat surface when needed. User will never have to worry about the battery life. It is a device that will help us in our everyday life, to keep our self connected and in shape. It is one significant piece of a system that will help us to look after the environment.

Without the new materials, i.e. new structures enabled by the novel materials and manufacturing methods it would be impossible to build Morph kind of device. Graphene has an important role in different components of the new device and the ecosystem needed to make the gateway and context awareness possible in an energy efficient way.

Graphene will enable evolution of the current technology e.g. continuation of the ever increasing computing power when the performance of the computing would require sub nanometer scale transistors by using conventional materials.

For someone who’s been following news of the Morph for the last few years, this news item doesn’t give you any new information. Still, it’s nice to be reminded of the Morph project. Here’s a video produced by the University of Cambridge that illustrates some of the project’s hopes for the Morph concept,

While the folks at the Nokia Research Centre and University of Cambridge have been working on their project, it appears the team at the Human Media Lab at the School of Computing at Queen’s University (Kingston, Ontario, Canada) in cooperation with a team from Arizona State University and E Ink Corporation have been able to produce a prototype of something remarkably similar, albeit with fewer functions. The PaperPhone is being introduced at the Association of Computing Machinery’s CHI 2011 (Computer Human Interaction) conference in Vancouver, Canada next Tuesday, May 10, 2011.

Here’s more about it from a May 4, 2011 news item on Nanowerk,

The world’s first interactive paper computer is set to revolutionize the world of interactive computing.

“This is the future. Everything is going to look and feel like this within five years,” says creator Roel Vertegaal, the director of Queen’s University Human Media Lab,. “This computer looks, feels and operates like a small sheet of interactive paper. You interact with it by bending it into a cell phone, flipping the corner to turn pages, or writing on it with a pen.”

The smartphone prototype, called PaperPhone is best described as a flexible iPhone – it does everything a smartphone does, like store books, play music or make phone calls. But its display consists of a 9.5 cm diagonal thin film flexible E Ink display. The flexible form of the display makes it much more portable that any current mobile computer: it will shape with your pocket.

For anyone who knows the novel, it’s very Diamond Age (by Neal Stephenson). On a more technical note, I would have liked more information about the display’s technology. What is E Ink using? Graphene? Carbon nanotubes?

(That does not look like to paper to me but I suppose you could call it ‘paperlike’.)

In reviewing all these news items, it seems to me there are two themes, the computer as bodywear and the computer as an extension of our thoughts. Both of these are more intimate relationships, the latter far more so than the former, than we’ve had with the computer till now. If any of you have any thoughts on this, please do leave a comment as I would be delighted to engage on some discussion about this.

You can get more information about the Association of Computing Machinery’s CHI 2011 (Computer Human Interaction) conference where Dr. Vertegaal will be presenting here.

You can find more about Dr. Vertegaal and the Human Media Lab at Queen’s University here.

The academic paper being presented at the Vancouver conference is here.

Also, if you are interested in the hardware end of things, you can check out E Ink Corporation, the company that partnered with the team from Queen’s and Arizona State University to create the PaperPhone. Interestingly, E Ink is a spin off company from the Massachusetts Institute of Technology (MIT).

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Science outreach and Nova’s Making Stuff series on PBS

Tuesday, February 8th, 2011

The February 2011 NISE (Nanoscale Informal Science Education) Net newsletter pointed me towards a video interview with Amy Moll, a materials scientist (Boise State University) being interviewed by Joe McEntee, group editor IOP Publishing, for the physicsworld.com video series,

Interesting discussion, yes? The Making Stuff series on PBS is just part of their (materials scientists’ working through their professional association, the Materials Research Society) science outreach effort. The series itself has been several years in the planning but is just one piece of a much larger effort.

All of which puts another news item into perspective. From the Feb. 7, 2011 news item on Nanowerk,

The Arizona Science Center is enlisting the expertise of professors in Arizona State University’s Ira A. Fulton Schools of Engineering in showcasing the latest advances in materials science and engineering.

The engineering schools are among organizations collaborating with the science center to present the Making Stuff Festival Feb. 18-20. [emphasis mine]

The event will explore how new kinds of materials are shaping the future of technology – in medicine, computers, energy, space travel, transportation and an array of personal electronic devices.

No one is making a secret of the connection,

The festival is being presented in conjunction with the broadcast of “Making Stuff”, a multi-part television series of the Public Broadcasting Service program NOVA that focuses on advances in materials technologies. It’s airing locally on KAET-Channel 8.

Channel 8 is another collaborator on the Making Stuff Festival, along with ASU’s Consortium for Science, Policy and Outcomes, the Arizona Technology Council, Medtronic, Intel and Science Foundation Arizona.

I highlight these items to point out how much thought, planning, and effort can go into science outreach.

Nano haikus (from the Feb. 2011 issue of the NISE Net Newsletter,

We received two Haikus from Michael Flynn expressing his hopes and fears for nanotechnology:

Miracle fibers
Weave a new reality
Built from the ground up

Too Small to be seen
This toxin is nanoscale
Can’t tell if it spilled

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