Tag Archives: Canadian budget 2009

Quantum dots possibly toxic? And a followup to the Canadian 2009 budget and Genome Canada

After last week’s (and continuing into this week) excitement over Canadian scientists creating the smallest quantum dot ever, there’s an article about possible toxicity in Science Daily here. The gist of the article is that quantum dots which are used in solar cells, medical imaging devices, and elsewhere could decompose during use or after they’re disposed. In any event, the decomposed dots could release metals that are toxic when they are exposed to acidic and/or alkaline environments. According to the article, there’s no need to sound an alarm yet but it’s a good idea to keep an eye on the situation.

I made a comment abut mapping genomes when discussing the science funding cuts in the Canadian budget which featured Genome Canada’s complete disappearance [from the budget].  I referred to a comment by Denise Caruso (she was featured in a Project on Emerging Nanotechnologies webcast discussing synthetic biology here). I’ve reviewed the webcast and found that she wasn’t referring to genome mapping per se but was discussing something called the Encode Study which was four years long and funded by the Human Genome Project. It featured an international consortium of 80 organizations that were working together to create an encyclopedia of DNA elements. Here’s a rough transcription of her comments,

We have no idea what we’re talking about here. The genes don’t operate the way we thought they did. The genome is not a tidy collection of independent genes where the sequence of DNA does this [action] and always does this so we can put it on a shelf [and have it on a] parts inventory list. [The genes] operate within networks. What they [study participants] said was almost 180 degrees opposite to what we have believed for quite some time.

Rick Weiss who was interviewing her went on to describe how a genes that are seemingly unrelated signal each other in ways that we had not expected. Who knows how it all works in the environment i.e. when you get out of the lab?

So getting back to my original point, mapping is fine but it’s not the most primary goal. As per the webcast, it’s the relationships or networks that are important.

A quick note: the University of Virginia has a virtual lab that features information and podcasts about nano. You can go here to see it.

Science funding cuts in the Canadian 2009 budget

Lost in all the excitement over Genome Canada’s disappearance from the budget is the drop in funding allocations for all three national research councils, Natural Sciences and Engineering Research Council (NSERC), National Research Council (NRC), and I think they’re including the Canadian Institutes of Health Research (CIHR) as the third one even though the name isn’t quite right. You can read up on the situation here and notice how the other three institutions are hardly mentioned.

Interestingly there was a recent article (Sat., Jan. 24, 2009) in the Globe and Mail about health research in Canada and how a great many US researchers flocked up because their funding was being limited and cut off in the US. Two researchers interviewed for the article mentioned that they were seeing similar signs of a freeze or even loss of funds, as they’d experienced in the US, on the horizon here as they were having problems with funding requests. (As I recall, the focus was on stem cell research but it might have been something else too.)

I am concerned in a general sense although I’m not a big fan of all this genomic mapping. How does mapping the genome of any organism help? As far as I can tell, all they’ve done is identify characteristics but they don’t understand how any of it works together. (I’m going to see if I can find a quote from Denise Caruso about genes and mapping them. As I recall, it hasn’t really amounted to anything much.)

While I disagree with some of the emphasis, I’m still concerned that all the science funding is being pulled back at this time. The whole thing is in stark contrast to the Obama administration’s interest in revitalizing and strengthening research in the US by pumping additional funds.