Tag Archives: Carl Zimmer

I found it at the movies: a commentary on/review of “Films from the Future”

Kudos to anyone who recognized the reference to Pauline Kael (she changed film criticism forever) and her book “I Lost it at the Movies.” Of course, her book title was a bit of sexual innuendo, quite risqué for an important film critic in 1965 but appropriate for a period (the 1960s) associated with a sexual revolution. (There’s more about the 1960’s sexual revolution in the US along with mention of a prior sexual revolution in the 1920s in this Wikipedia entry.)

The title for this commentary is based on an anecdote from Dr. Andrew Maynard’s (director of the Arizona State University [ASU] Risk Innovation Lab) popular science and technology book, “Films from the Future: The Technology and Morality of Sci-Fi Movies.”

The ‘title-inspiring’ anecdote concerns Maynard’s first viewing of ‘2001: A Space Odyssey, when as a rather “bratty” 16-year-old who preferred to read science fiction, he discovered new ways of seeing and imaging the world. Maynard isn’t explicit about when he became a ‘techno nerd’ or how movies gave him an experience books couldn’t but presumably at 16 he was already gearing up for a career in the sciences. That ‘movie’ revelation received in front of a black and white television on January 1,1982 eventually led him to write, “Films from the Future.” (He has a PhD in physics which he is now applying to the field of risk innovation. For a more detailed description of Dr. Maynard and his work, there’s his ASU profile webpage and, of course, the introduction to his book.)

The book is quite timely. I don’t know how many people have noticed but science and scientific innovation is being covered more frequently in the media than it has been in many years. Science fairs and festivals are being founded on what seems to be a daily basis and you can now find science in art galleries. (Not to mention the movies and television where science topics are covered in comic book adaptations, in comedy, and in standard science fiction style.) Much of this activity is centered on what’s called ’emerging technologies’. These technologies are why people argue for what’s known as ‘blue sky’ or ‘basic’ or ‘fundamental’ science for without that science there would be no emerging technology.

Films from the Future

Isn’t reading the Table of Contents (ToC) the best way to approach a book? (From Films from the Future; Note: The formatting has been altered),

Table of Contents
Chapter One
In the Beginning 14
Beginnings 14
Welcome to the Future 16
The Power of Convergence 18
Socially Responsible Innovation 21
A Common Point of Focus 25
Spoiler Alert 26
Chapter Two
Jurassic Park: The Rise of Resurrection Biology 27
When Dinosaurs Ruled the World 27
De-Extinction 31
Could We, Should We? 36
The Butterfly Effect 39
Visions of Power 43
Chapter Three
Never Let Me Go: A Cautionary Tale of Human Cloning 46
Sins of Futures Past 46
Cloning 51
Genuinely Human? 56
Too Valuable to Fail? 62
Chapter Four
Minority Report: Predicting Criminal Intent 64
Criminal Intent 64
The “Science” of Predicting Bad Behavior 69
Criminal Brain Scans 74
Machine Learning-Based Precognition 77
Big Brother, Meet Big Data 79
Chapter Five
Limitless: Pharmaceutically-enhanced Intelligence 86
A Pill for Everything 86
The Seduction of Self-Enhancement 89
Nootropics 91
If You Could, Would You? 97
Privileged Technology 101
Our Obsession with Intelligence 105
Chapter Six
Elysium: Social Inequity in an Age of Technological
Extremes 110
The Poor Shall Inherit the Earth 110
Bioprinting Our Future Bodies 115
The Disposable Workforce 119
Living in an Automated Future 124
Chapter Seven
Ghost in the Shell: Being Human in an
Augmented Future 129
Through a Glass Darkly 129
Body Hacking 135
More than “Human”? 137
Plugged In, Hacked Out 142
Your Corporate Body 147
Chapter Eight
Ex Machina: AI and the Art of Manipulation 154
Plato’s Cave 154
The Lure of Permissionless Innovation 160
Technologies of Hubris 164
Superintelligence 169
Defining Artificial Intelligence 172
Artificial Manipulation 175
Chapter Nine
Transcendence: Welcome to the Singularity 180
Visions of the Future 180
Technological Convergence 184
Enter the Neo-Luddites 190
Techno-Terrorism 194
Exponential Extrapolation 200
Make-Believe in the Age of the Singularity 203
Chapter Ten
The Man in the White Suit: Living in a Material World 208
There’s Plenty of Room at the Bottom 208
Mastering the Material World 213
Myopically Benevolent Science 220
Never Underestimate the Status Quo 224
It’s Good to Talk 227
Chapter Eleven
Inferno: Immoral Logic in an Age of
Genetic Manipulation 231
Decoding Make-Believe 231
Weaponizing the Genome 234
Immoral Logic? 238
The Honest Broker 242
Dictating the Future 248
Chapter Twelve
The Day After Tomorrow: Riding the Wave of
Climate Change 251
Our Changing Climate 251
Fragile States 255
A Planetary “Microbiome” 258
The Rise of the Anthropocene 260
Building Resiliency 262
Geoengineering the Future 266
Chapter Thirteen
Contact: Living by More than Science Alone 272
An Awful Waste of Space 272
More than Science Alone 277
Occam’s Razor 280
What If We’re Not Alone? 283
Chapter Fourteen
Looking to the Future 288
Acknowledgments 293

The ToC gives the reader a pretty clue as to where the author is going with their book and Maynard explains how he chose his movies in his introductory chapter (from Films from the Future),

“There are some quite wonderful science fiction movies that didn’t make the cut because they didn’t fit the overarching narrative (Blade Runner and its sequel Blade Runner 2049, for instance, and the first of the Matrix trilogy). There are also movies that bombed with the critics, but were included because they ably fill a gap in the bigger story around emerging and converging technologies. Ultimately, the movies that made the cut were chosen because, together, they create an overarching narrative around emerging trends in biotechnologies, cybertechnologies, and materials-based technologies, and they illuminate a broader landscape around our evolving relationship with science and technology. And, to be honest, they are all movies that I get a kick out of watching.” (p. 17)

Jurassic Park (Chapter Two)

Dinosaurs do not interest me—they never have. Despite my profound indifference I did see the movie, Jurassic Park, when it was first released (someone talked me into going). And, I am still profoundly indifferent. Thankfully, Dr. Maynard finds meaning and a connection to current trends in biotechnology,

Jurassic Park is unabashedly a movie about dinosaurs. But it’s also a movie about greed, ambition, genetic engineering, and human folly—all rich pickings for thinking about the future, and what could possibly go wrong. (p. 28)

What really stands out with Jurassic Park, over twenty-five years later, is how it reveals a very human side of science and technology. This comes out in questions around when we should tinker with technology and when we should leave well enough alone. But there is also a narrative here that appears time and time again with the movies in this book, and that is how we get our heads around the sometimes oversized roles mega-entrepreneurs play in dictating how new tech is used, and possibly abused. These are all issues that are just as relevant now as they were in 1993, and are front and center of ensuring that the technologyenabled future we’re building is one where we want to live, and not one where we’re constantly fighting for our lives.  (pp. 30-1)

He also describes a connection to current trends in biotechnology,

De-Extinction

In a far corner of Siberia, two Russians—Sergey Zimov and his son Nikita—are attempting to recreate the Ice Age. More precisely, their vision is to reconstruct the landscape and ecosystem of northern Siberia in the Pleistocene, a period in Earth’s history that stretches from around two and a half million years ago to eleven thousand years ago. This was a time when the environment was much colder than now, with huge glaciers and ice sheets flowing over much of the Earth’s northern hemisphere. It was also a time when humans
coexisted with animals that are long extinct, including saber-tooth cats, giant ground sloths, and woolly mammoths.

The Zimovs’ ambitions are an extreme example of “Pleistocene rewilding,” a movement to reintroduce relatively recently extinct large animals, or their close modern-day equivalents, to regions where they were once common. In the case of the Zimovs, the
father-and-son team believe that, by reconstructing the Pleistocene ecosystem in the Siberian steppes and elsewhere, they can slow down the impacts of climate change on these regions. These areas are dominated by permafrost, ground that never thaws through
the year. Permafrost ecosystems have developed and survived over millennia, but a warming global climate (a theme we’ll come back to in chapter twelve and the movie The Day After Tomorrow) threatens to catastrophically disrupt them, and as this happens, the impacts
on biodiversity could be devastating. But what gets climate scientists even more worried is potentially massive releases of trapped methane as the permafrost disappears.

Methane is a powerful greenhouse gas—some eighty times more effective at exacerbating global warming than carbon dioxide— and large-scale releases from warming permafrost could trigger catastrophic changes in climate. As a result, finding ways to keep it in the ground is important. And here the Zimovs came up with a rather unusual idea: maintaining the stability of the environment by reintroducing long-extinct species that could help prevent its destruction, even in a warmer world. It’s a wild idea, but one that has some merit.8 As a proof of concept, though, the Zimovs needed somewhere to start. And so they set out to create a park for deextinct Siberian animals: Pleistocene Park.9

Pleistocene Park is by no stretch of the imagination a modern-day Jurassic Park. The dinosaurs in Hammond’s park date back to the Mesozoic period, from around 250 million years ago to sixty-five million years ago. By comparison, the Pleistocene is relatively modern history, ending a mere eleven and a half thousand years ago. And the vision behind Pleistocene Park is not thrills, spills, and profit, but the serious use of science and technology to stabilize an increasingly unstable environment. Yet there is one thread that ties them together, and that’s using genetic engineering to reintroduce extinct species. In this case, the species in question is warm-blooded and furry: the woolly mammoth.

The idea of de-extinction, or bringing back species from extinction (it’s even called “resurrection biology” in some circles), has been around for a while. It’s a controversial idea, and it raises a lot of tough ethical questions. But proponents of de-extinction argue
that we’re losing species and ecosystems at such a rate that we can’t afford not to explore technological interventions to help stem the flow.

Early approaches to bringing species back from the dead have involved selective breeding. The idea was simple—if you have modern ancestors of a recently extinct species, selectively breeding specimens that have a higher genetic similarity to their forebears can potentially help reconstruct their genome in living animals. This approach is being used in attempts to bring back the aurochs, an ancestor of modern cattle.10 But it’s slow, and it depends on
the fragmented genome of the extinct species still surviving in its modern-day equivalents.

An alternative to selective breeding is cloning. This involves finding a viable cell, or cell nucleus, in an extinct but well-preserved animal and growing a new living clone from it. It’s definitely a more appealing route for impatient resurrection biologists, but it does mean getting your hands on intact cells from long-dead animals and devising ways to “resurrect” these, which is no mean feat. Cloning has potential when it comes to recently extinct species whose cells have been well preserved—for instance, where the whole animal has become frozen in ice. But it’s still a slow and extremely limited option.

Which is where advances in genetic engineering come in.

The technological premise of Jurassic Park is that scientists can reconstruct the genome of long-dead animals from preserved DNA fragments. It’s a compelling idea, if you think of DNA as a massively long and complex instruction set that tells a group of biological molecules how to build an animal. In principle, if we could reconstruct the genome of an extinct species, we would have the basic instruction set—the biological software—to reconstruct
individual members of it.

The bad news is that DNA-reconstruction-based de-extinction is far more complex than this. First you need intact fragments of DNA, which is not easy, as DNA degrades easily (and is pretty much impossible to obtain, as far as we know, for dinosaurs). Then you
need to be able to stitch all of your fragments together, which is akin to completing a billion-piece jigsaw puzzle without knowing what the final picture looks like. This is a Herculean task, although with breakthroughs in data manipulation and machine learning,
scientists are getting better at it. But even when you have your reconstructed genome, you need the biological “wetware”—all the stuff that’s needed to create, incubate, and nurture a new living thing, like eggs, nutrients, a safe space to grow and mature, and so on. Within all this complexity, it turns out that getting your DNA sequence right is just the beginning of translating that genetic code into a living, breathing entity. But in some cases, it might be possible.

In 2013, Sergey Zimov was introduced to the geneticist George Church at a conference on de-extinction. Church is an accomplished scientist in the field of DNA analysis and reconstruction, and a thought leader in the field of synthetic biology (which we’ll come
back to in chapter nine). It was a match made in resurrection biology heaven. Zimov wanted to populate his Pleistocene Park with mammoths, and Church thought he could see a way of
achieving this.

What resulted was an ambitious project to de-extinct the woolly mammoth. Church and others who are working on this have faced plenty of hurdles. But the technology has been advancing so fast that, as of 2017, scientists were predicting they would be able to reproduce the woolly mammoth within the next two years.

One of those hurdles was the lack of solid DNA sequences to work from. Frustratingly, although there are many instances of well preserved woolly mammoths, their DNA rarely survives being frozen for tens of thousands of years. To overcome this, Church and others
have taken a different tack: Take a modern, living relative of the mammoth, and engineer into it traits that would allow it to live on the Siberian tundra, just like its woolly ancestors.

Church’s team’s starting point has been the Asian elephant. This is their source of base DNA for their “woolly mammoth 2.0”—their starting source code, if you like. So far, they’ve identified fifty plus gene sequences they think they can play with to give their modern-day woolly mammoth the traits it would need to thrive in Pleistocene Park, including a coat of hair, smaller ears, and a constitution adapted to cold.

The next hurdle they face is how to translate the code embedded in their new woolly mammoth genome into a living, breathing animal. The most obvious route would be to impregnate a female Asian elephant with a fertilized egg containing the new code. But Asian elephants are endangered, and no one’s likely to allow such cutting edge experimentation on the precious few that are still around, so scientists are working on an artificial womb for their reinvented woolly mammoth. They’re making progress with mice and hope to crack the motherless mammoth challenge relatively soon.

It’s perhaps a stretch to call this creative approach to recreating a species (or “reanimation” as Church refers to it) “de-extinction,” as what is being formed is a new species. … (pp. 31-4)

This selection illustrates what Maynard does so very well throughout the book where he uses each film as a launching pad for a clear, readable description of relevant bits of science so you understand why the premise was likely, unlikely, or pure fantasy while linking it to contemporary practices, efforts, and issues. In the context of Jurassic Park, Maynard goes on to raise some fascinating questions such as: Should we revive animals rendered extinct (due to obsolescence or inability to adapt to new conditions) when we could develop new animals?

General thoughts

‘Films for the Future’ offers readable (to non-scientific types) science, lively writing, and the occasional ‘memorish’ anecdote. As well, Dr. Maynard raises the curtain on aspects of the scientific enterprise that most of us do not get to see.  For example, the meeting  between Sergey Zimov and George Church and how it led to new ‘de-extinction’ work’. He also describes the problems that the scientists encountered and are encountering. This is in direct contrast to how scientific work is usually presented in the news media as one glorious breakthrough after the next.

Maynard does discuss the issues of social inequality and power and ownership. For example, who owns your transplant or data? Puzzlingly, he doesn’t touch on the current environment where scientists in the US and elsewhere are encouraged/pressured to start up companies commercializing their work.

Nor is there any mention of how universities are participating in this grand business experiment often called ‘innovation’. (My March 15, 2017 posting describes an outcome for the CRISPR [gene editing system] patent fight taking place between Harvard University’s & MIT’s [Massachusetts Institute of Technology] Broad Institute vs the University of California at Berkeley and my Sept. 11, 2018 posting about an art/science exhibit in Vancouver [Canada] provides an update for round 2 of the Broad Institute vs. UC Berkeley patent fight [scroll down about 65% of the way.) *To read about how my ‘cultural blindness’ shows up here scroll down to the single asterisk at the end.*

There’s a foray through machine-learning and big data as applied to predictive policing in Maynard’s ‘Minority Report’ chapter (my November 23, 2017 posting describes Vancouver’s predictive policing initiative [no psychics involved], the first such in Canada). There’s no mention of surveillance technology, which if I recall properly was part of the future environment, both by the state and by corporations. (Mia Armstrong’s November 15, 2018 article for Slate on Chinese surveillance being exported to Venezuela provides interesting insight.)

The gaps are interesting and various. This of course points to a problem all science writers have when attempting an overview of science. (Carl Zimmer’s latest, ‘She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity’] a doorstopping 574 pages, also has some gaps despite his focus on heredity,)

Maynard has worked hard to give an comprehensive overview in a remarkably compact 279 pages while developing his theme about science and the human element. In other words, science is not monolithic; it’s created by human beings and subject to all the flaws and benefits that humanity’s efforts are always subject to—scientists are people too.

The readership for ‘Films from the Future’ spans from the mildly interested science reader to someone like me who’s been writing/blogging about these topics (more or less) for about 10 years. I learned a lot reading this book.

Next time, I’m hopeful there’ll be a next time, Maynard might want to describe the parameters he’s set for his book in more detail that is possible in his chapter headings. He could have mentioned that he’s not a cinéaste so his descriptions of the movies are very much focused on the story as conveyed through words. He doesn’t mention colour palates, camera angles, or, even, cultural lenses.

Take for example, his chapter on ‘Ghost in the Shell’. Focused on the Japanese animation film and not the live action Hollywood version he talks about human enhancement and cyborgs. The Japanese have a different take on robots, inanimate objects, and, I assume, cyborgs than is found in Canada or the US or Great Britain, for that matter (according to a colleague of mine, an Englishwoman who lived in Japan for ten or more years). There’s also the chapter on the Ealing comedy, The Man in The White Suit, an English film from the 1950’s. That too has a cultural (as well as, historical) flavour but since Maynard is from England, he may take that cultural flavour for granted. ‘Never let me go’ in Chapter Two was also a UK production, albeit far more recent than the Ealing comedy and it’s interesting to consider how a UK production about cloning might differ from a US or Chinese or … production on the topic. I am hearkening back to Maynard’s anecdote about movies giving him new ways of seeing and imagining the world.

There’s a corrective. A couple of sentences in Maynard’s introductory chapter cautioning that in depth exploration of ‘cultural lenses’ was not possible without expanding the book to an unreadable size followed by a sentence in each of the two chapters that there are cultural differences.

One area where I had a significant problem was with regard to being “programmed” and having  “instinctual” behaviour,

As a species, we are embarrassingly programmed to see “different” as “threatening,” and to take instinctive action against it. It’s a trait that’s exploited in many science fiction novels and movies, including those in this book. If we want to see the rise of increasingly augmented individuals, we need to be prepared for some social strife. (p. 136)

These concepts are much debated in the social sciences and there are arguments for and against ‘instincts regarding strangers and their possible differences’. I gather Dr. Maynard hies to the ‘instinct to defend/attack’ school of thought.

One final quandary, there was no sex and I was expecting it in the Ex Machina chapter, especially now that sexbots are about to take over the world (I exaggerate). Certainly, if you’re talking about “social strife,” then sexbots would seem to be fruitful line of inquiry, especially when there’s talk of how they could benefit families (my August 29, 2018 posting). Again, there could have been a sentence explaining why Maynard focused almost exclusively in this chapter on the discussions about artificial intelligence and superintelligence.

Taken in the context of the book, these are trifling issues and shouldn’t stop you from reading Films from the Future. What Maynard has accomplished here is impressive and I hope it’s just the beginning.

Final note

Bravo Andrew! (Note: We’ve been ‘internet acquaintances/friends since the first year I started blogging. When I’m referring to him in his professional capacity, he’s Dr. Maynard and when it’s not strictly in his professional capacity, it’s Andrew. For this commentary/review I wanted to emphasize his professional status.)

If you need to see a few more samples of Andrew’s writing, there’s a Nov. 15, 2018 essay on The Conversation, Sci-fi movies are the secret weapon that could help Silicon Valley grow up and a Nov. 21, 2018 article on slate.com, The True Cost of Stain-Resistant Pants; The 1951 British comedy The Man in the White Suit anticipated our fears about nanotechnology. Enjoy.

****Added at 1700 hours on Nov. 22, 2018: You can purchase Films from the Future here.

*Nov. 23, 2018: I should have been more specific and said ‘academic scientists’. In Canada, the great percentage of scientists are academic. It’s to the point where the OECD (Organization for Economic Cooperation and Development) has noted that amongst industrialized countries, Canada has very few industrial scientists in comparison to the others.

Immune to CRISPR?

I guess if you’re going to use bacteria as part of your gene editing technology (CRISPR [clustered regularly interspaced short palindromic repeats]/Cas9) then, you might half expect the body’s immune system may have developed some defenses. A Jan. 9, 2018 article by Sarah Zhang for The Atlantic provides some insight into what the new research suggests (Note: Links have been removed),

2018 is supposed to be the year of CRISPR in humans. The first U.S. and European clinical trials that test the gene-editing tool’s ability to treat diseases—such as sickle-cell anemia, beta thalassemia, and a type of inherited blindness—are slated to begin this year.

But the year has begun on a cautionary note. On Friday [January 5, 2018], Stanford researchers posted a preprint (which has not been peer reviewed) to the website biorXiv highlighting a potential obstacle to using CRISPR in humans: Many of us may already be immune to it. That’s because CRISPR actually comes from bacteria that often live on or infect humans, and we have built up immunity to the proteins from these bacteria over our lives.

Not all CRISPR therapies in humans will be doomed. “We don’t think this is the end of the story. This is the start of the story,” says Porteus [Matthew Porteus, a pediatrician and stem-cell researcher at Stanford]. There are likely ways around the problem of immunity to CRISPR proteins, and many of the early clinical trials appear to be designed around this problem.

Porteus and his colleagues focused on two versions of Cas9, the bacterial protein mostly commonly used in CRISPR gene editing. One comes from Staphylococcus aureus, which often harmlessly lives on skin but can sometimes causes staph infections, and another from Streptococcus pyogenes, which causes strep throat but can also become “flesh-eating bacteria” when it spreads to other parts of the body. So yeah, you want your immune system to be on guard against these bacteria.

The human immune system has a couple different ways of recognizing foreign proteins, and the team tested for both. First, they looked to see if people have molecules in their blood called antibodies that can specifically bind to Cas9. Among 34 people they tested, 79 percent had antibodies against the staph Cas9 and 65 percent against the strep Cas9.

The Stanford team only tested for preexisting immunity against Cas9, but anytime you inject a large bacterial protein into the human body, it can provoke an immune response. After all, that’s how the immune system learns to fight off bacteria it’s never seen before. (Preexisting immunity can make the response faster and more robust, though.)

The danger of the immune system turning on a patient’s body hangs over a lot of research into correcting genes. In the late 1990s and 2000s, research into gene therapy was derailed by the death of 18-year-old Jesse Gelsinger, who died from an immune reaction to the virus used to deliver the corrected gene. This is the worst-case scenario that the CRISPR world hopes to avoid.

Here’s a link to and a citation for the preprint,

Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans by Carsten Trevor Charlesworth, Priyanka S Deshpande, Daniel P Dever, Beruh Dejene, Natalia Gomez-Ospina, Sruthi Mantri, Mara Pavel-Dinu, Joab Camarena, Kenneth I Weinberg, Matthew H Porteus. bioRxiv posted January 5, 2018 doi: https://doi.org/10.1101/243345

This article is a preprint and has not been peer-reviewed …

This preprint (not yet published paper) is open access and open for feedback.

Meanwhile, the year of CRISPR takes off (from a January 10, 2018 American Chemical Society news release on EurekAlert),

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research. That’s because the first company-sponsored clinical studies will be conducted to see if it can help treat diseases in humans, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society.

C&EN Assistant Editor Ryan Cross reports that a big push is coming from industry, specifically from three companies that are each partly founded by one of the three inventors of the method. They are zeroing in on the blood diseases called sickle-cell anemia and β-thalassemia, mostly because their precise cause is known. In these diseases, hemoglobin doesn’t function properly, leading to severe health issues in some people. Crispr Therapeutics and Intellia Therapeutics plan to test the technique to boost levels of an alternative version of healthy hemoglobin. Editas Medicine, however, will also use CRISPR to correct mutations in the faulty hemoglobin gene. Labs led by university researchers are also joining the mix, starting or continuing clinical trials with the approach in 2018.

Because CRISPR is being used to cut a cell’s DNA and insert a new sequence, concerns have been raised about the potential for accidents. A cut in the wrong place could mean introducing a new mutation that could be benign — or cancerous. But according to proponents of the method, researchers are conducting extensive computer predictions and in vitro tests to help avoid this outcome.

The January 8, 2018 Chemical and Engineering News (C&EN) open access article by Ryan Cross is here.

Finally, if you are interested in how this affects research as it’s being developed, there’s University of British Columbia researcher Rosie Redfield’s January 16, 2018 posting on RRResearch blog,

Thursday’s [January 11, 2018] post described the hypothesis that bacteria might use gene transfer agent particles to inoculate other cells in the population with fragments of phage DNA, and outlined an experiment to test this.  Now I’m realizing that I need to know a lot more about the kind of immunity I should expect to see if this GTA-as-vaccine hypothesis is correct.

That should give you some idea of what I meant by “research as it’s being developed.” Redfield’s blog is not for the mildly interested.

Redfield is well-known internationally as being one of the first to refute research which suggested the existence of an ‘arsenic bacterium’ (see my Dec. 8, 2010 posting: My apologies for arsenic blooper. She’s first mentioned in the second excerpt, second paragraph.) The affair was known online as #arseniclife. There’s a May 27, 2011 essay by Carl Zimmer on Slate titled: The Discovery of Arsenic-Based Twitter: How #arseniclife changed science.

American Assocation for the Advancement of Science (AAAS) meeting in Chicago, Illinois (13 – 17 February 2014)

The 2014 annual meeting of the American Association for the Advancement of Science (AAAS) will take place Feb. 13 – 17, 2014 in Chicago (one of my favourite places), Illinois. It’s always interesting to take a look at the programme and here’s a few of the items I found interesting,

Thursday, Feb. 13, 2014  the AAAS has arranged a number of talks about ‘communicating science and, as usual, bloggers, etc. are confined to presenting under the rubric of social media:

9:00 AM-10:30 AM

Seminar: Communicating Science

11:00 AM-12:30 PM

Seminar: Communicating Science

Engaging with Social Media

To be more specific, here’s the list of presenters for the ‘Journalist’ talk (Note: I have removed links),

Moderator:
Cornelia Dean, The New York Times and Brown University
Speakers:
Carl Zimmer, Independent Science Journalist [Note: Zimmer writes for the NY Times and other prestigious print publications, as well as, being a blogger]

Robert Lee Hotz, The Wall Street Journal

David Baron, Public Radio International

Paula Apsell, NOVA [science program on the US PBS {Public Broadcasting Service} network)

[emphases mine]

Meanwhile, we have this for social media,

Moderator:
Dominique Brossard, University of Wisconsin
Speakers:
Kim Cobb, University of Georgia
Navigating the Science-Social Media Space: Pitfalls and Opportunities
Danielle N. Lee, Cornell University
Raising STEM Awareness Among Under-Served and Under-Represented Audiences
Maggie Koerth-Baker, BoingBoing.net
What’s the Point of Social Media?

It’s nice to see Danielle N. Lee as one of the presenters. Her blog, The Urban Scientist is on the Scientific American blog network (she also featured as a whistle blower and more in the 2013 science blogging scandals [my first post on the topic was Oct. 18, 2013 towards the end of the scandals and I mused on the scandals and discussed  gender in an end-of-year Dec. 31, 2013 posting ) and there’s of course, someone representing BoingBoing, an online publisher,which was conceptualized as a magazine and has now evolved into a group blog.

My basic thesis is that blogs and such are emerging as part of the science media landscape and the types of sessions which isolate bloggers, etc.  do not acknowledge that fact. Yes, it’s true that Zimmer blogs but I can guarantee that the discussion will revolve exclusively around his high profile publishers such as the NY Times and how the participants can get their stories in front of mainstream media journalists and as for the social media session that’s going to focus on how scientists can directly approach their publics.

Moving on, there’s a nanotechnology aspect to the following presentation, although you’d never guess it from the title,

 Preserving Our Cultural Heritage: Science in the Service of Art
Friday, 14 February 2014: 10:00 AM-11:30 AM
Acapulco (Hyatt Regency Chicago)
In 2009 a group of chemists and materials scientists from a wide range of institutions came together for a workshop on “Chemistry and Materials Research at the Interface Between Science and Art,” co-sponsored by the Andrew W. Mellon Foundation and the National Science Foundation. One of the workshop conclusions was that scientists in academia need to be encouraged to collaborate with their peers in cultural heritage institutions, to both increase scientist knowledge of this heritage and also to develop the necessary tools and apply the science to be able to preserve it. The session covers different collaborations that are ongoing in this area, relating to different mediums of art and different technologies that can be applied. The session will also include recent results and successes in this process, both in better understanding of materials as well as in developments for their conservation. The discussion will also address what is needed for collaborations like this to continue to flourish and grow.

One doesn’t get to the ‘nano’ part until looking at the speakers’ list (Note: Links have been removed),

Organizer:
Nicholas Bigelow, University of Rochester
Co-Organizer:
Leonor Sierra, University of Rochester
Speakers:
Nicholas Bigelow, University of Rochester
21st Century Tools for 19th Century Nanotechnology ‘[emphasis mine]
Richard Van Duyne, Northwestern University
Detecting Organic Dyestuffs in Art with SERS
Anikó Bezur, Yale University
Aiming for a Perfect Match: Pairing Collections-Based Scientific Research with Academia

The 19th Century nanotechnology referred to in the title of Biglow’s talk is the daggeureotype (a type of 19th century photographic process) which gained a lot of attention in the last few years when a display of irreplaceable pieces started showing signs of visible (25 pieces) and catastrophic (five pieces) deterioration. There’s more about this fascinating story in my Jan. 10, 2013 posting.

Saturday, Feb.15, 2014, Alan Alda will be at the meeting as a plenary speaker,

Alan Alda: Getting Beyond a Blind Date with Science
Plenary Lecture
Saturday, 15 February 2014: 5:00 PM-6:00 PM
Imperial Ballroom (Fairmont Chicago)
Alan Alda is an actor, writer, director, and visiting professor at the Alan Alda Center for Communicating Science at Stony Brook University, where he helps current and future scientists learn to communicate more clearly and vividly with the public. In collaboration with theater arts faculty at Stony Brook, he is pioneering the use of improvisational theater exercises to help scientists connect more directly with people outside their field. Alda is best known for his award-winning work in movies, theater, and television, but he also has a distinguished record in the public communication of science. For 13 years he hosted the PBS series Scientific American Frontiers, which he has called “the best thing I ever did in front of a camera.” After interviewing hundreds of scientists around the world, he became convinced that many researchers have wonderful stories but need to learn how to tell them better. That realization inspired the creation of Stony Brook’s multidisciplinary Alan Alda Center for Communicating Science in 2009.

The last two sessions I’m highlighting are on standard nanotechnology topics. On Sunday, Feb. 16, 2014, there’s

Nanoelectronics for Renewable Energy: How Nanoscale Innovations Address Global Needs
Sunday, 16 February 2014: 1:30 PM-4:30 PM
Regency B (Hyatt Regency Chicago)
Sometimes it’s possible to get a handle on the world’s biggest problems by thinking creatively on a very small scale—and advances in the rapidly maturing field of nanoelectronics prove it. Innovations that hold promise for broader and faster adoption of renewable energy technologies loom large against a backdrop of population growth, rapid industrialization in developing countries, and initiatives to decrease reliance on both fossil fuels and nuclear power. In this symposium, researchers from the U.S. and Europe will review the latest progress in nanoelectronics for renewable energy across a series of interrelated programs. For instance, new manufacturing approaches such as nanoimprinting, nanotransfer, and spray-on fabrication of organic semiconductors not only point the way toward low-cost production of large-scale electronics such as solar panels, they also enable and inspire novel nanoelectronic device designs. These device-level innovations range from ultrasensitive molecular sensors to nanomagnet logic circuits, and they are of particular interest in solar energy applications. Many lines of research appear to be converging on nanostructure-based solar cells that will be vastly more efficient in capturing sunlight (or even heat) and converting it to electrical power. In addition to outlining these promising paths toward higher-efficiency, lower-cost photovoltaics, the symposium will highlight some of the remaining hurdles, including needed advances in fundamental science.
Organizer:
Patrick Regan, Technical University Munich
Co-organizers:
William Gilroy, University of Notre Dame
and Hillary Sanctuary, Swiss Federal Institute of Technology (EPFL)

On Monday, Feb. 17, 2014,  nanotechnology features in the final plenary session,

John A. Rogers: Stretchy Electronics That Dissolve in Your Body
Plenary Lecture
Monday, 17 February 2014: 8:30 AM-9:30 AM
Imperial Ballroom (Fairmont Chicago)
Dr. John Rogers’ research includes fundamental and applied aspects of nano- and molecular scale fabrication. He also studies materials and patterning techniques for unusual electronic and photonic devices, with an emphasis on bio-integrated and bio-inspired systems. He received a Ph.D. in physical chemistry from Massachusetts Institute of Technology in 2005. He has published more than 350 papers and is an inventor on over 80 patents and patent applications, many of which are licensed or in active use by large companies and startups that he co-founded. He previously worked for Bell Laboratories as director of its research program in condensed matter physics. He has received recognition including a MacArthur Fellowship from the John D. and Catherine T. MacArthur Foundation, the Lemelson-MIT Prize, the National Security Science and Engineering Faculty Fellowship from the U.S. Department of Defense, the George Smith Award from IEEE, the Robert Henry Thurston Award from American Society of Mechanical Engineers, the Mid-Career Researcher Award from Materials Research Society, the Leo Hendrick Baekeland Award from the American Chemical Society, and the Daniel Drucker Eminent Faculty Award from the University of Illinois.
Speaker:
John Rogers, Ph. D., University of Illinois, Urbana-Champaign

You can find out more about registration and public events for the AAAS 2014 annual meeting here.

Organizer:
Nicholas Bigelow, University of Rochester
Co-Organizer:
Leonor Sierra, University of Rochester
Speakers:
Nicholas Bigelow, University of Rochester
21st Century Tools for 19th Century Nanotechnology

Richard Van Duyne, Northwestern University
Detecting Organic Dyestuffs in Art with SERS

Anikó Bezur, Yale University
Aiming for a Perfect Match: Pairing Collections-Based Scientific Research with Academia

AAAS 2013 meeting in Boston,US and Canadian research excellence

The 2013 annual meeting for the American Association for the Advancement of Science (AAAS) will be held in Boston, Massachusetts from Feb. 14 – 18, 2013 with a much better theme this year, The Beauty and Benefits of Science, than last year’s, Flattening the World. (It didn’t take much to improve the theme, eh?)

Plenary speakers range from AAAS’s president, William N. Press to Nathan Myhrvold, a venture capitalist to astrophysicist, Robert Kirshner to Cynthia Kenyon, a molecular biologist to Sherry Turkle. From the AAAS webpage describing Turkle’s 2013 plenary lecture,

Sherry Turkle

Abby Rockefeller Mauzé Professor of the Social Studies of Science and Technology in the Program in Science, Technology, and Society, MIT

The Robotic Moment: What Do We Forget When We Talk to Machines?

Dr. Turkle is founder and director of the MIT Initiative on Technology and Self. She received a joint doctorate in sociology and personality psychology from Harvard University and is a licensed clinical psychologist. Her research focuses on the psychology of human relationships with technology, especially in the realm of how people relate to computational objects. She is an expert on mobile technology, social networking, and sociable robotics and a regular media commentator on the social and psychological effects of technology. Her most recent book is Alone Together: Why We Expect More from Technology and Less from Each Other.

Given my experience last year in the 2012 meeting media room, I’m surprised to see a social media session is planned, from the session webpage,

Engaging with Social Media
Communicating Science
Thursday, February 14, 2013: 3:00 PM-4:30 PM
Ballroom A (Hynes Convention Center)

In a constantly changing online landscape, what is the best way for scientists and engineers to engage the public through social media? This session will discuss how people are accessing science information via blogs and social networks and the importance of researchers getting involved directly. [emphasis mine]  Speakers will address the ways that researchers can create meaningful interactions with the public through social media.

Organizer: Cornelia Dean, The New York Times
Co-Organizer: Dennis Meredith, Science Communication Consultant
Moderator: Carl Zimmer, Independent Science Journalist

Speakers:
XXXX Scicurious, Neurotic Physiology
Science Blogging for Fun and Profit
Christie Wilcox, University of Hawaii
Science in a Digital Age
Dominique Brossard, University of Wisconsin
Science and the Public in New Information Environments

I’d love to see how the theme of ‘researcher engaging directly’ gets developed. In theory, I have no problems with the concept. Unfortunately, those words are sometimes code for this perspective, ‘only experts (scientists/accredited journalists) should discuss or write about science’. A couple of quick comments, my Jan. 13, 2012 posting featured an interview with Carl Zimmer, this session’s moderator, about his science tattoo book and Dominique Brossard, one of the speakers, was last mentioned here in my Jan. 24, 2013 posting titled, Tweet your nano, in the context of a research study on social media and nanotechnology.

In keeping with the times (as per my Jan. 28, 2013 posting about the colossal research prizes for the Graphene and Human Brain Project initiatives), the 2012 AAAS annual meeting features a Brain Function and Plasticity thread or subtheme. There’s this session amongst others,

The Connectome: From the Synapse to Brain Networks in Health and Disease
Brain Function and Plasticity
Saturday, February 16, 2013: 8:30 AM-11:30 AM
Room 304 (Hynes Convention Center)

A series of innovative studies are being done to map the brain from the molecular to the systems level both structurally and functionally. At the synaptic level, how neurotransmitters, their receptors, and signaling pathways influence neural function and plasticity is becoming much better understood. Integrating neuronal function at the level of single neurons and groups of neurons into larger circuits at the anatomical level in the mammalian brain, while a daunting task, is being studied by advanced imaging techniques requiring vast amounts of information storage and processing. To integrate local circuit function with whole brain function, understanding the structure and processing of brain networks is critical. A major project to accomplish this task, the Human Connectome Project, is in the process of integrating the structure and function of brain networks using the most advanced imaging and analysis techniques in 1,200 people, including twins and their nontwin siblings. This step will allow for major new insights into not only brain structure and function, but also their genetic underpinnings. Comparing this information in both the normal brain and in different brain disorders such as neurodegenerative diseases is providing novel insights into how understanding brain function from the molecular to the systems level will provide insights into normal brain function and disease pathogenesis as well as provide new treatment strategies.

Organizer:

David Holtzman, Washington University

Speakers:

Mark F. Bear, Massachusetts Institute of Technology
Molecules and Mechanisms Involved in Synaptic Plasticity in Health and Disease
Jeff Lichtman, Harvard University
Connectomics: Developing a Wiring Diagram for the Mammalian Brain
Steve Petersen, Washington University
The Human Connectome Project
Marcus E. Raichle, Washington University
The Brain’s Dark Energy and the Default Mode Network
Nicole Calakos, Duke University
Synaptic Plasticity in the Basal Ganglia in Health and Disease
William W. Seeley, University of California
Brain Networks: Linking Structure and Function in Neurodegenerative Diseases

Then, there’s this session featuring graphene,

What’s Hot in Cold
Sunday, February 17, 2013: 8:30 AM-11:30 AM
Room 308 (Hynes Convention Center)

The study of ultracold atoms and molecules is now the frontier of low-temperature science, reaching temperatures of a few hundred picokelvin above absolute zero. This field was made possible by a technique that did not exist 30 years ago: laser cooling of atoms. It is hardly obvious that the laser, which produces the most intense light on Earth and is routinely used in industrial applications for cutting and welding medal, would also provide the most powerful coolant. Such are the surprises of science, where a breakthrough in one area transforms others in unexpected ways. Since 1997, eight Nobel Laureates in physics have been recognized for contributions to ultracold atomic and molecular science, which has become one of the most vibrant fields in physics, cutting across traditional disciplinary boundaries, e.g., atomic, molecular, and optical; condensed matter; statistical physics; and nuclear and particle physics. This field builds on two accomplishments that it was the first to achieve: first, the production of quantum degenerate matter using a wide range of elements and, second, exquisite control of quantum degenerate matter at the atomic level. These have led to record low temperatures, ultraprecise atomic clocks, and new forms of quantum matter that generalize ideas from magnetism superconductivity and graphene physics.

Organizer:

Charles W. Clark, Joint Quantum Institute

Speakers:

Markus Greiner, Harvard University
Quantum Simulation: A Microscopic View of Quantum Matter
Ana Maria Rey, University of Colorado
Atomic Clocks: From Precise Timekeepers to Quantum Simulators
Daniel Greif, ETH Zurich
Exploring Dirac Points with Ultracold Fermions in a Tunable Honeycomb Lattice
Gretchen Campbell, Joint Quantum Institute
Superflow in Bose-Einstein Condensate Rings: Tunable Weak Links in Atom Circuits
Benjamin Lev, Stanford University
New Physics in Strongly Magnetic Ultracold Gases

Amongst all these other sessions, there’s a session about Canadian science,

Introduction to Canadian Research Excellence: Evidence & Examples
Friday, February 15, 2013: 11:00 AM-12:00 PM
Room 205 (Hynes Convention Center)

The Canada Pavilion in the Exhibit Hall gives a taste of what lies north of Boston and the 49th parallel. Join us at this workshop to learn about opportunities in Canada for research and study. Canada recently completed a comprehensive analysis of its domestic science and technology strengths. The final report of the expert panel of the Council of Canadian Academies will be presented, including the use of global benchmarks and insights on international collaborations. Two of the drivers for Canadian excellence will be introduced: large-scale science facilities in key fields and a system of targeted fellowships and research chairs that recruit globally.

Coordinator:

Tim Meyer, TRIUMF

Presenters:

Tim Meyer, TRIUMF,
Chad Gaffield, Social Sciences and Humanities Research Council of Canada
Eliot Phillipson, University of Toronto

“Introduced,” really? Large scale science facilities are not new in Canada or anywhere else for that matter and the programmes of targeted fellowships have been around long enough and successful enough that it is being copied.

First, there was the Canada Research Chair programme, which was instituted in 2000. From the About Us page (Note: A link has been removed),

The Canada Research Chairs program stands at the centre of a national strategy to make Canada one of the world’s top countries in research and development. [emphasis mine]

In 2000, the Government of Canada created a permanent program to establish 2000 research professorships—Canada Research Chairs—in eligible degree-granting institutions across the country.

The Canada Research Chairs program invests $300 million per year to attract and retain some of the world’s most accomplished and promising minds.

This was programme was followed up with the Canada Excellence Research Chairs Program in 2008, from the Background page (Note: A link has been removed),

Launched in 2008, the Canada Excellence Research Chairs (CERC) Program supports Canadian universities in their efforts to build on Canada’s growing reputation as a global leader in research and innovation. The program awards world-renowned researchers and their teams up to $10 million over seven years to establish ambitious research programs at Canadian universities. These awards are among the most prestigious and generous available globally.

In May 2010, the first group of Canada Excellence Research Chairs was announced. Selected through a rigorous, multilevel peer review process, these chairholders are helping Canada build a critical mass of expertise in the four priority research areas of the federal government’s science and technology strategy …

Here’s an excerpt from my Feb. 21, 2012 posting,

Canadians have been throwing money at scientists for some years now (my May 20, 2010 posting about the Canada Excellence Research Chairs programme). We’ve attempted to recruit from around the world with our ‘research chairs’ and our ‘excellence research chairs’ and our Network Centres of Excellence (NCE) all serving as enticements.

The European Research Council (ERC) has announced that they will be trying to beat us at our own game at the AAAS 2012 annual meeting in Vancouver (this new ERC programme was launched in Boston, Massachusetts in January 2012).

The Canadian report these folks will be discussing was released in Sept. 2012 and was  featured here in a two-part commentary,

The State of Science and Technology in Canada, 2012 report—examined (part 1: the executive summary)

The State of Science and Technology in Canada, 2012 report—examined (part 2: the rest of the report)

My Sept. 27, 2012 posting features my response to the report’s launch on that day.

As for the AAAS 2013 annual meeting, there’s a lot, lot more of it and it’s worth checking out, if for no other reason than to anticipate the types of science stories you will be seeing in the coming months.

AAAS 2012 the last day, Feb. 20, 2012

Hopefully I’m still making some sense as it’s been an exhausting few days and I’m not even going to the parties or expected to attend the 6:30 am meetings.

This last day featured one of my favourite talks. It was called, “Good Natured: From Primate Social Instincts to Human Morality” and was given by Frans B. M. de Waal. What really made the talk fascinating were the video clips which illustrated de Waal’s experiments with various animals. (I’m miffed that I can’t find any of these clips to embed in this posting because just hearing or reading about the animal’s behaviour isn’t the same.)

The best I can do is offer is this brief clip of de Waal speaking with Carl Zimmer (science writer mentioned in my Jan. 13, 2012 posting about his book on science tattoos). Here’s de Waal describing his experiments with Capuchin monkeys and the discovery he and his colleagues made about the concept of fairness amongst monkeys,

(You can check out more video clips of events held by the Templeton Book Forum here.)

At his AAAS 2012 talk, de Waals featured clips of elephants working cooperatively or not. Apparently, some of the elephants discovered that they could trick their partners into doing all of the work while still receiving the reward. de Waal is careful to note that his work is with mammals.

The very last session I attended was titled, “Misreporting Fukushima: A Failure of Science Journalism with Global Repercussions?” My hat’s off to Tracey Brown (Sense about Science) who moderated the session. Thank you and your colleague for keeping on time and for managing to get as many as questions heard and answered as possible. (There were lineups of people trying to ask questions and I’ve seen moderators disappoint a significant percentage of the questioners in this type of situation.) Brown did something simple, she aggregated the questions and gave a warning (10 mins., I think) before she wrapped up the session.

As for the ‘misreporting’, it’s one of the topics that people can talk about forever. It was good to hear from scientists and journalists (from the UK, Germany, and China) and audience members (from Japan, Canada, US, India, etc.) and, as you might expect, many dissenting opinions and perspectives were offered. I very much appreciated the civil and thoughtful discussion.

Science tattoos and a brief chat with Carl Zimmer about his book, Science Ink

I’m back with another New York Academy of Sciences public event (my Jan. 3, 2012 posting listed a number of events), this time it’s  Science Ink: Tattoos of the Science Obsessed with Carl Zimmer. Here’s a description of the event (which will take place on Tuesday, Jan. 24, 2012 from 7 – 8:30 pm),

How much do you love science? Enough to get it permanently inked on your skin?

Join award-winning science journalist and New York Academy of Sciences regular Carl Zimmer for a talk on his latest book, Science Ink, which showcases over 300 tattoos dedicated to the pursuit of science.

Tattoos have been a part of human culture as far back as Neolithic times. Scientists have uncovered tattoos on mummified ancients from Western China to Egypt to Scandanavia. And the subjects of those tattoos vary as much as the cultures—from elaborate animal and organic designs to simple graphic designs thought to have therapeutic qualities. In more modern times in the Western world, tattoos came into vogue in the late 1800s when British elites began to tattoo themselves—both Winston Churchill and his mother, Lady Randolph Churchill, had tattoos. And today, it’s clear that in American culture, tattoos have had a resurgence in popularity.

Choosing what to mark your body with permanently is a source of much conversation and consternation. And as Carl Zimmer discovered after a blog post asking about science tattoos, there is a passionate group of people who made the choice to ink themselves with science.

In this special event, Zimmer will speak about the science and history of tattooing, and offer highlights from his book Science Ink, which features a gallery of scientific tattoos, spanning fields from evolutionary biology and neuroscience to mathematics and astrophysics. In addition, Zimmer is inviting a handful of those featured in the book to come and share the compelling personal stories behind their ink.

Here are more details about the event, pricing is as follows,

Member:                                                                   $15

Student / Postdoc / Fellow Member:           $10

Nonmember:                                                           $25

Student / Postdoc / Fellow Nonmember:   $20

In a Jan. 9, 2012 posting on his blog, The Loom, Carl Zimmer offers more information about his book and upcoming talk plus a discount,

Get $10 dollars off admission by using the promo code ZIMMER. Register [here or http://www.nyas.org/scienceink]

The address and contact details:

The New York Academy of Sciences

7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600
nyas@nyas.org

As for Carl Zimmer and science tattoos, I decided to investigate a bit further. Here’s an excerpt from Carl Zimmer’s website bio webpage,

The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” In his books, essays, articles, and blog posts, Zimmer reports from the frontiers of biology, where scientists are expanding our understanding of life. He is a popular speaker at universities, medical schools, museums, and festivals, and he is also a frequent guest on radio programs such as Radio Lab and This American Life.

In addition to writing books, Zimmer has written hundreds of articles for the New York Times and magazines including National Geographic, Time, Scientific American, Science, and Popular Science. From 1994 to 1998 Zimmer was a senior editor at Discover, where he remains a contributing editor and writes a monthly column about the brain.

Since 2003, Zimmer has written the award-winning blog, The Loom. Along with essays about science, The Loom is also home to a popular gallery of science tattoos. In November 2011, Zimmer will publish a book of his favorite selections, called Science Ink: Tales of the Science Obsessed.

Zimmer is a lecturer at Yale University, where he teaches writing about science and the environment. He was also the first Visiting Scholar at the Science, Health, and Environment Reporting Program at New York University’s Arthur L. Carter Journalism Institute.

He is, to his knowledge, the only writer after whom a species of tapeworm has been named. [emphasis mine]

I do love a sense of humour. As for Zimmer’s latest book, Science Ink, his website offers some excerpts from it (here are a few samples),

Astrarium, p.71
“Although I’m not a scientist by trade,” writes Lauren Caldwell, “my work on seventeenth- and eighteenth-century British literature has provided ample opportunity for me to become acquainted with the work of some brilliant scientific innovators. Though we have discarded some of their ideas, their work retains all of its vital visual force. ¶ “Years ago I discovered and fell in love with the comprehensive diagrams in Giovanni de’Dondi’s 1364 Il Tractatus Astarii, which contained the plans for the first famous astrarium. Each piece has its own delicate mechanical beauty, but I chose for my backpiece the Mercury wheelwork. Of course, you couldn’t track Mercury with it—de’Dondi followed Ptolemy—but his astrarium remains a lovely and impressive testament to human ingenuity and curiosity. ¶ “The more spare geometrical diagrams that surround the de’Dondi piece are taken from Sir Isaac Newton’s Principia Mathematica—of which little enough, I imagine, need be said. Though in many respects these two men couldn’t have been more different, they shared a vision of a universe as elegant and aesthetically compelling today as it was when they lived and worked.”

Astrarium tattoo (from Science Ink by Carl Zimmer)

DNA monster, bottom p.102
Jay Phelan, a biologist at UCLA, got his DNA tattoo in 1990 while he was in graduate school. “As I got deeper into the study of evolution, genetics, and human behavior,” he writes, “I realized that there was a tension between what my genes ‘wanted’ me to do and what I wanted to do, from the fattiness of the foods I ate, to the selfishness/selflessness I showed to others, to issues with managing my money, my risk-taking, and my relationships, and more. It dawned on me that I was fighting a never-ending battle. Anyway, I tried to come up with a design that captured that tension and, once I did, decided to get it tattooed on my back.”

DNA monster tattoo (from Science Ink by Carl Zimmer)

I was sufficiently fascinated to send off a few questions to Carl Zimmer about science tattoos and his upcoming talk at the NYAS and he very kindly replied,

  • Given the title of your latest book (Science Ink: Tattoos of the Science Obsessed), I’m wondering if you have any tattoos.
    If so, what is it?

I don’t have any tattoos actually. I’ve never been particularly interested in getting one, and am no big fan of needles. But I find the lack of a tattoo is no impediment to appreciating the tattoos of scientists.  If I sell of whole bunch of copies of the book, maybe I’ll have to celebrate by getting one. I was thinking about getting  my wife’s name, Grace, spelled out as amino acids.

  • What most surprised you about this book?

At first the surprise was simply that any scientist at all had tattoos.  The initial flood of pictures that filled up my e-mail inbox was amazing. After I got accustomed to the idea that there is lots and lots of scientists with tattoos out there, the next big surprise was how many interesting stories there were, illustrated by these tattoos. Stories from the history of science, stories from the personal lives of the scientists. And since telling stories is my job, I decided to turn Science Ink into a book of miniature essays.

  • Is there any branch of science that attracts more people who are willing to ink their bodies?

I don’t see any field being way in the lead compared other ones. In fact, what really impressed me was that just about every branch of science I can imagine ended up being represented in the book. I have groups of linguistics tattoos in the book, astronomy tattoo,s medical tattoos ,tattoos about quantum physics, and so on. Basically, by looking at these tattoos you end up taking a tour of all science.

  • Could you briefly preview a little bit of your Ja.24.12 talk?

I’m going to be talking at the New York Academy of Sciences about what got me into this peculiar project, and some of the things I learned about scientists and science in the process. But I’m also going to be talking about tattooing itself. It’s actually a pretty fascinating scientific subject in its own right. Anthropologists have found evidence of tattooing in many cultures around the world, and it goes back thousands of years. So I think that tattoos speak to something really important about what it means to be human–and, in this particular case, what it means to be a scientist.

Dear Carl, Thank you for taking time out of a very busy schedule (he has a talk scheduled Jan. 20, 2012 too; scroll down to the next paragraph for information about that event plus all of his usual work) to respond. I hope the book is a huge success.

There is one other related Science Ink event that might be of interest. The ScienceOnline2012 conference, January 19 – 21, 2012 (no spaces left for attendees), held annually in Durham, North Carolina and (mentioned in my Nov. 2, 2011 posting) is hosting a Science of Ink tour for 30 people to the Dogstar Tattoo Company on Friday, Jan. 20, 2012. The webpage for the tour notes that it is completely booked but if you follow the Twitter hash tag (#SciInk) you may be able to get on the tour (as people do drop out of these things for one reason or another). From the tour webpage,

Join us on Friday afternoon, January 20th, at the Dogstar Tattoo Company in Durham, NC’s Golden Belt district for a lecture by Carl Zimmer on the science of tattoos, a reception & tour of the studio, and the opportunity to get inked (or just watch the process!). Carl will have his book, Science Ink: The Tattoos of the Science Obsessed available–and we can probably convince him to sign a few ☺

This isn’t your typical tattoo shop. When Carl Zimmer first saw the photos, he declared, “It’s like a cathedral of tattoo parlors.”

When you register, please indicate if you definitely plan to get a tattoo, might want to get a tattoo, or definitely don’t plan to get inked (but want to observe). [emphasis mine]

Good luck with getting on the tour or getting to the talk in New York. As for anyone from Vancouver who might be hoping that Carl Zimmer will be here for the American Association for the Advancement of Science (AAAS) 2012 annual meeting, sadly, the answer is no.

Sick and tired of the ‘social media is changing how science is practiced’ narrative

The whole ‘social media is changing ______’ puzzles me. You can fill in the blank with science/government/social relationships/etc. It’s always the same notion. Somehow social media is engendering changes the like of which we’ve never seen before.

  • The February 2011 overthrow of Mubarak in Egypt was all due to social media, as is the current social unrest in many Middle Eastern Countries.
  • Social relationships are being negatively impacted (nobody talks to anybody else anymore or it’s opening new avenues for relationships)
  • The practice of science is being changed by the use of social media.
  • etc.

Mostly I’m concerned with the one about science since I recently ended up on a panel where the discussion turned on this topic. I think there are a lot of things having an impact on how science is practiced and trying to establish the role social media is playing, if any, is a little premature.

We had Rosie Redfield on the panel. Rosie is a professor at the University of British Columbia who was part of the ‘arsenic life’ story that took the internet by a storm in late November/early December 2010. (Confession: I got caught up in the excitement in my Dec. 6, 2010 posting and recanted in my Dec. 8, 2010 posting.) Recently, there’s been a story about ‘arsenic life’ by Carl Zimmer for Slate magazine titled, How #arseniclife changed science. Here’s Zimmer’s set up (from the Slate article),

On November 29, NASA announced that it would soon hold a press conference to “discuss an astrobiology finding that will impact the search for evidence of extraterrestrial life.” Wild speculation ran amok—perhaps scientists had found living things on one of Saturn’s moons. At the press conference, the scientists did not unveil an actual extraterrestrial, but they did have big news. A new paper had just been published in the journal Science, they said, which described bacteria that seemed able to build their own DNA from arsenic. If that were true, it would be an historic discovery, because no such ability has ever been found among Earth’s life-forms.

The paper was published online in late November and attracted a great deal of discussion and criticism almost immediately on blogs (Rosie Redfield’s RRResearch amongst them) and on twitter via the hash tag topic, #arseniclife. The print version of the paper, along with critical letters, will appear in the June 3, 2011 issue of Science.

Here’s Zimmer’s take on what makes this particular scientific dust-up different,

For those of us who have been tracking #arseniclife since last Thanksgiving, however, today comes as an anticlimax. There’s not much in the letters to Science that we haven’t read before. In the past, scientists might have kept their thoughts to themselves, waiting for journals to decide when and how they could debate the merits of a study. But this time, they started talking right away, airing their criticisms on the Internet. In fact, the true significance of the aliens-that-weren’t will be how it helped change the way scientists do science.

Zimmer goes on to describe this new practice,

Redfield and her colleagues are starting to carry out a new way of doing science, known as post-publication peer review. Rather than leaving the evaluation of new studies to a few anonymous scientists, researchers now debate the merit of papers after they have been published. The collective decision they come to stays open to revision.

Post-publication peer review—and open science in general—is attracting a growing number of followers in the scientific community. But some critics have argued that it’s been more successful in theory than in practice. The #arseniclife affair is one of the first cases in which the scientific community openly vetted a high-profile paper, and influenced how the public at large thought about it.

Post-publication peer review existed before social media as per ‘cold fusion’ (Wikipedia essay). I remember it because I wasn’t particularly interested in science at the time but this was everywhere and it went on for months. There was the initial excitement and enthusiasm (the ‘cold fusion’ scientists were featured on the cover of Times or Newsweek or maybe both in the days when those magazines were powerhouse publications). Then, as the initial enthusiasm died down, the storm of scientific criticism started (those other scientists may not have had social media but they made themselves felt). The story took place over eight to 10 months and achieved public awareness in a way that scientists can only fantasize about these days.  By comparison, the arsenic story blew up and disappeared from public consciousness within roughly two weeks, if that.

Social media may yet change how science is practiced but I wouldn’t use Zimmer’s story about #arsencilife to support that belief, in fact, I think it could support another idea altogether.

The ‘arsenic’ story was, by comparison, with ‘cold fusion’ greatly truncated and most members of the public never really heard about it and, as a consequence, were not exposed to the furious debate and discussion as they were with  ‘cold fusion’.  They did not get exposed to how science ‘really works and therein lies a problem because they did not see the uncertainties, the mistakes, and revised ideas.

As for what factors may be having an impact on scientific practice, I’d suggest reading Identifying good scientists and keeping them honest on The Black Hole blog by David Kent. Here’s an excerpt,

In a February 2011 interview with Lab Times, Cambridge scientist Peter Lawrence1 reflects on his own career and complains that “the heart of research is sick” as he charts the changes in the way in which science is pursued.  Briefly, he cites impact factors and the increased need to assign metrics to scientists (# of publications, H-index, etc) as main drivers of producing low quality research and unfairly squeezing out some good scientists who do not publish simply for the sake of publishing.  Impact factor fever runs deep throughout laboratories but, most damagingly, exists at the funding agency and university administrative level as well.

ETA June 17, 2011: For anyone who’d like to read some updated and contrasting discussion about the #arseniclife aftermath for scientific practice and science education there are two June 16, 2011 guest posts for Scientific American, one from Rosie Redfield and the other from Marie-Claire Shanahan. Plus, if you are interested in more details about the cold fusion story and the role electronic communication played, check out Marie-Claire Shanahan’s post,  Arsenic, cold fusion and the legitimacy of online critique, on the Boundary Vision blog.

Synthetic biology bumps up against James Joyce and copyright

Who knew? Well, apparently the James Joyce estate found out that J. Craig Venter coded a quote from Joyce’s ‘A Portrait of the Artist as a Young Man’ into some synthetic DNA in May 2010 and the JJ estate didn’t like it.

Venter and his team made headlines internationally in May 2010 because they replaced the DNA in a bacterium with DNA they had created, i.e., synthetic DNA. Here’s how the problem with the James Joyce estate arose (from the March 14, 2011 David Ewalt article on Forbes),

In order to distinguish their synthetic DNA from that naturally present in the bacterium, Venter’s team coded several famous quotes into their DNA, including one from James Joyce’s A Portrait of the Artist of a Young Man: “To live, to err, to fall, to triumph, to recreate life out of life.”

After announcing their work, Venter explained, his team received a cease and desist letter from Joyce’s estate, saying that he’d used the Irish writer’s work without permission. ”We thought it fell under fair use,” said Venter.

Carl Zimmer over on The Loom (a Discover magazine blog) offers some additional commentary in his March 15, 2011 posting,

Last year I wrote about how Craig Venter and his colleagues had inscribed a passage from James Joyce into the genome of a synthetic microbe. The line, “To live, to err, to fall, to triumph, to recreate life out of life,” was certainly apropos, but it was also ironic, since it is now being defaced as Venter’s microbes multiply and mutate.

Man, do I wish this would go to court! Imagine the legal arguments. I wonder what would happen if the court found in the Joyce estate’s favor. Would Venter have to pay for every time his microbes multiplied? Millions of little acts of copyright infringement?

I was under the impression that the JJ estate folks are very protective and litigious and sure enough I found an item confirming that impression this morning. Mike Mangan in his March 16, 2011 post on Techdirt offers some perspective on this state of affiairs and on Venter’s own IP (intellectual property) adventures,

Craig Venter, who is no stranger to advocating stronger and stronger IP laws — especially in the area of “synthetic life” — apparently learned recently how those laws can reach ridiculous levels. In a recent presentation, he noted that his team had encoded a James Joyce quote in the DNA of the “synthetic life” he’s been trying to create. However, the James Joyce estate was not amused and sent him a cease-and-desist. Venter notes that he felt that it was fair use to include a quote.

This isn’t the first time that the Joyce estate has done stuff like this, including an attempt to stifle a biography by use of a copyright claim. In that case, the estate finally learned that they had no claim when they actually had to pay up to settle the case.

I think Mangan is in the right when he calls it ridiculous. By the way, Venter inscribed another quote in the synthetic DNA, this one from Richard Feynman. Here’s what Venter wrote,

“What I cannot built, I cannot understand.”

Venter got it wrong. As per Ewalt’s article, Feynman’s quote should have been (apparently the folks from the California Institute of Technology, where Feynman worked, sent Venter an image of the blackboard where Feynman composed the quote),

“What I cannot create, I cannot understand.”

What fascinates me in all this is that quote no longer exist. From Zimmer’s May 21, 2010 posting about Venter, James Joyce and synthetic life,

The fate of Joyce’s DNA points up something important about this project. There have been lots of headlines over the past day about how the scientists who made this cell were playing God. Yet our power, even over synthetic cells, is limited. Once this new cell came into existence, it started changing through evolution, slipping away from its original form. In fact, evolution is the great enemy of all scientists who want to use synthetic biology to supply us with medicine, fuel, and other valuable things. Once they engineer a microbe, they start to lose control of their handiwork. Life takes its own course from there. It is life, ultimately, that recreates life from life.

I previously posted about Venter’s synthetic biology project on May 21, 2010 and posted about Venter’s upcoming visit to Vancouver on March 7, 2011.