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Georges Canguilhem’s influence on life sciences philosophy and ‘it’s all about Kant’

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This July 5, 2023 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) press release by José Tadeu Arantes (also on EurekAlert but published on July 3, 2023) slow walks us through a listing of French intellectuals and some history (which I enjoyed) before making a revelation,

The constitution of the World Health Organization (WHO) defines health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity”. The definition dates from the 1940s, but even then the thinking behind it was hardly novel. Similar concepts can be found in antiquity, in Eastern as well as Western societies, but in Europe, the cradle of Western culture, the view that mental well-being was part of health enjoyed little prestige in the eighteenth and nineteenth centuries owing to a reductionist understanding of disease as strictly somatic (relating only to the body). This outlook eventually began to be questioned. One of its leading critics in the twentieth century was French philosopher and physician Georges Canguilhem (1904-1995).

A disciple of Gaston Bachelard (1884-1962), a colleague of Jean-Paul Sartre (1905-1980), Paul Nizan (1905-1940) and Raymond Aron (1905-1983), and a major influence on Michel Foucault (1926-1984), Canguilhem was one of the foremost French intellectuals of the postwar years. Jacques Lacan (1901-1981), Gilles Deleuze (1925-1995) and Jacques Derrida (1930-2004) were among the thinkers who took inspiration from his ideas.

Canguilhem began studying medicine in the mid-thirties and earned his medical doctorate in 1943, by which time he had already taught philosophy in high schools for many years (having qualified in 1927). Another significant tack in his life course occurred during World War Two. He had long been both a pacifist and an antifascist. Following the French surrender in 1940, he refused to continue teaching under the Vichy regime and joined the Resistance, fighting with the rural guerrillas of the Maquis. In this historically and politically complex period, he apparently set out to train as a physician in order to have practical experience as well as book learning and to work on the history of the life sciences. He was awarded the Croix de Guerre and the Médaille da la Résistance for organizing a field hospital while under attack in the Auvergne.

In an article published in the journal History and Philosophy of the Life Sciences, Emiliano Sfara, who has a PhD in philosophy from the University of Montpellier and was a postdoctoral fellow at the University of São Paulo (USP) in Brazil from 2018 to 2022, argues that Canguilhem’s concepts of “technique”, “technical activity” and “practice” derived from Immanuel Kant’s Critique of Judgment (1790) and influenced Canguilhem’s decision to study medicine.

“Earlier historiographical research showed how Kant influenced Canguilhem, especially the concept of ‘knowledge’ developed in Kant’s Critique of Pure Reason as the unification of heterogeneous data by an organizing intellect, and the idea of the ‘organism’ as a totality of interdependent and interacting parts, inspired by the Critique of Judgment. I tried to show in the article the importance, and roots in Kant, of a third cluster of ideas relating to the concept of ‘technique’ in Canguilhem’s work, beginning in mid-thirties,” said Sfara, currently a researcher at the National Institute of Science and Technology for Interdisciplinary and Transdisciplinary Studies in Ecology and Evolution (INCT IN-TREE), hosted by the Federal University of Bahia (UFBA).

“Section 43 of Kant’s Critique of Judgment makes a distinction between technical capacity and science as a theoretical faculty. Technique is the subject’s concrete practice operating in a certain context, a vital movement of construction or manufacturing of objects and tools that enable a person to live in their environment. This is not reducible to science. Analogously, Canguilhem postulates that science is posterior to technique. Practice comes first; theory arises later. This movement is evident in art. True, the artist starts out with a project. But the development of the artwork isn’t confined to the project, which is reconstructed as the process unfolds. This practical element of the subject’s interaction with the environment, which has its roots in Kant’s theories, was very important to the evolution of Canguilhem’s thought. It even influenced his decision to study medicine, as well as the conception of medicine he developed.”

Sfara explained that while Canguilhem espoused the values of the Parti Radical in his youth, in the mid-thirties he moved left, without becoming a pro-Soviet Stalinist. Later on, according to some scholars who knew him and are still active (such as the Moroccan philosopher and mathematician Hourya Benis Sinaceur), Canguilhem gave primacy to the egalitarian principles symbolized by the French Republic’s motto Liberté, Egalité, Fraternité.

His main contributions were to medicine and philosophy of science. His most important work, The Normal and the Pathological (1966), is basically an expansion of his 1943 doctoral thesis. “In his original thesis, Canguilhem broke with part of eighteenth- and nineteenth-century French medical tradition and formulated ideas that are very much part of medicine today. [emphasis mine] Taking a purely analytical and quantitative approach, physicians like François Broussais (1772-1838) believed disease resulted from a surplus or lack of some organic substance, such as blood. Bloodletting was regularly used as a form of treatment. France imported 33 million leeches from southern Europe in the first half of the nineteenth century. Canguilhem saw the organism as a totality that interacted with its environment [emphasis mine] rather than a mere aggregation of parts whose functioning depended only on a ‘normal’ amount of the right organic substances,” Safra said.

In Canguilhem, the movement changes. Instead of transiting from the part to the whole, he moves from the whole to the part (as does Kant in the Critique of Judgment). He views the organism not as a machine but as an integral self-regulating totality. Life cannot be deduced from physical and chemical laws. One must start from the living being to understand life. Practice is the bridge that connects this totality to the environment. At the same time as it changes the environment, practice changes the organism and helps determine its physiological states.

“So Canguilhem implies that in order to find a state called normal, i.e. healthy, a given organism has to adapt its own operating rules to the outside world in the course of interacting concretely and practically with the environment. A human organism, for example, is in a ‘normal’ state when its pulse slows sharply after a period of long daily running. A case in point is the long-distance runner, who has to train every day,” Safra said.

“For Canguilhem, disease is due to inadaptation between the part, the organism and the environment, and often manifests itself as a feeling of malaise. Adaptive mechanisms in the organism can correct pathological dysfunctions.”

The article resulted from Sfara’s postdoctoral research supervised by Márcio Suzuki and supported by FAPESP.

The article “From technique to normativity: the influence of Kant on Georges Canguilhem’s philosophy of life” is at: link.springer.com/article/10.1007/s40656-023-00573-8.

This text was originally published by FAPESP Agency according to Creative Commons license CC-BY-NC-ND. Read the original here.https://agencia.fapesp.br/republicacao_frame?url=https://agencia.fapesp.br/study-shows-kants-influence-on-georges-canguilhem-who-anticipated-concepts-current-in-medicine-today/41794/&utm_source=republish&utm_medium=republish&utm_content=https://agencia.fapesp.br/study-shows-kants-influence-on-georges-canguilhem-who-anticipated-concepts-current-in-medicine-today/41794/

Even though you can find a link to the paper in the press release, here’s my version of a citation complete with link,

From technique to normativity: the influence of Kant on Georges Canguilhem’s philosophy of life by Emiliano Sfara .History and Philosophy of the Life Sciences volume 45, Article number: 16 (2023) DOI: https://doi.org/10.1007/s40656-023-00573-8 Published: 06 April 2023

This paper is open access.

When poetry feels like colour, posture or birdsong plus some particle fiction

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A June 10, 2022 Tallinn University (Estonia) press release (also on EurekAlert but published on June 16, 2022 on behalf of the Estonian Research Council) provides information on a fascinating PhD thesis examining poetry in a very new way,

In addition to searching for the meaning of poems, they can also often be described through the emotions that the reader feels while reading them. Kristiine Kikas, a doctoral student at the School of Humanities of Tallinn University, studied which other sensations arise whilst reading poetry and how they affect the understanding of poems.

The aim of the doctoral thesis was to study the palpability of language [emphasis mine], i.e. sensory saturation, which has not found sufficient analysis and application so far. “In my research, I see reading as an impersonal process, meaning the sensations that arise do not seem to belong to either the reader or the poetry, but to both at the same time,” Kikas describes the perspective of her thesis.

In general, the language of poetry is studied metaphorically, in order to try to understand what a word means either directly or figuratively. A different perspective called “affective perspective” usually studies the effects of pre-linguistic impulses or impulses not related to the meaning of the word on the reader. However, Kikas viewed language as a simultaneous proposition and flow of consciousness, i.e. a discussion moving from one statement to another as well as connections that seem to occur intuitively while reading. She sought to identify ways to approach verbal language, that is considered to trigger analytical thinking in particular, in a way that would help open up sensory saturation and put their observation in poetic analysis at the forefront along with other modes of studying poetry. To achieve her goals, Kikas applied Gilles Deleuze’s method of radical empiricism and compared several other approaches with it: semiotics, biology, anthropology, modern psychoanalysis and cognitive sciences. [emphases mine]

Kikas describes reading in her doctoral thesis as a constant presence in verbal language, which is sometimes more and sometimes less pronounced. This type of presence can be felt like colour, posture or birdsong [emphasis mine]. “Following the neuroscientific origins of metaphors, I used the human organism’s tendency to perceive language at the sensory-motor level in my close reading to help replay it using body memory. This trait allows us to physically experience the words we read,” explains Kikas. According to her, the sensations stored in the body evoked by words can be considered the oneness of the reader and the words, or the reader’s becoming the words. Kikas emphasises that this can only happen if the multiplicity of sensations and meanings that arise during reading are recognised.

“Although the study showed that the saturations associated with verbal language cannot be linked to a broader literary discourse without representational and analytical thinking, the conclusion is that noticing and acknowledging them is important in both experiencing and interpreting the poem,” summarises Kikas her doctoral thesis. As her research was only the first attempt in examining sensations in poetry, Kikas hopes to provide material for further discussion. Above all, she encourages readers in their attempts to understand poetry to notice and trust even the slightest sensations and impulses triggered while reading, as these are the beginning of even the most abstract meaning.

I was able to track down the thesis ‘Uncommonness in the Commonplace: Reading for Senseation in Poetry‘ to here where the title is in English but the rest of the entry is in Estonian. Unfortunately, it’s not possible to download the thesis, which I believe is written in English.

Particle fiction

This is a somewhat older thesis and is only loosely related in that it is about literary matters and there’s a science aspect to it too. Tania Hershman, “poet, writer, teacher and editor based in Manchester, UK,” adds this from the about page on her eponymous website, Note: I have moved the paragraphs into a different order,

… After making a living for 13 years as a science journalist, writing for publications such as WIRED and NewScientist, I gave it all up to write fiction, later also poetry and hybrid pieces, and am now based in Manchester in the north of England. I have a first degree in Maths and Physics, a diploma in journalism, an MSc in Philosophy of Science, an MA and a PhD in Creative Writing.

…

My hybrid book, And What If We Were All Allowed to Disappear, was published in a limited edition by Guillemot Press in March 2020. It is now sold out but can be read in electronic form as part of my PhD in Creative Writing, ‘Particle fictions: an experimental approach to creative writing and reading informed by particle physics’, available to be downloaded from Bath Spa University here: http://researchspace.bathspa.ac.uk/10693/.

…

You can download her PhD thesis (Particle fictions: an experimental approach to creative writing and reading informed by particle physics). This abstract offers a few highlights,

This two-part document comprises the work submitted for Tania Hershman’s practice-based PhD in Creative Writing in answer to her primary research question: Can particle fiction and particle physics interrogate each other? Her secondary research question examined the larger question of wholeness and wholes versus parts. The first of the two elements of the PhD is a book-length creative work of what Hershman has defined as “particle fiction” – a book made of parts which works as a whole – entitled ‘And What If We Were All Allowed to Disappear’: an experimental, hybrid work comprised of prose, poetry, elements that morph between the two forms, and images, and takes concepts from particle physics as inspiration. The second element of this PhD, the contextualising research, entitled ‘And What If We Were All Allowed To Separate And Come Together’, which is written in the style of fictocriticism, provides an overview of particle physics and the many other topics relating to wholeness and wholes versus parts – from philosophy to postmodernism and archaeology – that Hershman investigated in the course of her project. This essay also details the “experiments” Hershman carried out on works which she defined as particle fictions, in order to examine whether it was possible to generalise and formulate a “Standard Model of Particle Fiction” inspired by a the Standard Model of Particle Physics, and to inform the creation of her own work of particle fiction.

Enjoy!

North Carolina universities go beyond organ-on-a-chip

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The researchers in the North Carolina universities involved in this project have high hopes according to an Oct. 9, 2015 news item on Nanowerk,

A team of researchers from the University of North Carolina at Chapel Hill and NC State University has received a $5.3 million, five-year Transformative Research (R01) Award from the National Institutes of Health (NIH) to create fully functioning versions of the human gut that fit on a chip the size of a dime.

Such “organs-on-a-chip” have become vital for biomedical research, as researchers seek alternatives to animal models for drug discovery and testing. The new grant will fund a technology that represents a major step forward for the field, overcoming limitations that have mired other efforts.

The technology will use primary cells derived directly from human biopsies, which are known to provide more relevant results than the immortalized cell lines used in current approaches. In addition, the device will sculpt these cells into the sophisticated architecture of the gut, rather than the disorganized ball of cells that are created in other miniature organ systems.

“We are building a device that goes far beyond the organ-on-a-chip,” said Nancy L. Allbritton, MD, PhD, professor and chair of the UNC-NC State joint department of biomedical engineering and one of four principle investigators on the NIH grant. “We call it a ‘simulacrum,’ [emphasis mine] a term used in science fiction to describe a duplicate. The idea is to create something that is indistinguishable from your own gut.”

I’ve come across the term ‘simulacrum’ in relation to philosophy so it’s a bit of a surprise to find it in a news release about an organ-on-a-chip where it seems to have been redefined somewhat. Here’s more from the Simulacrum entry on Wikipedia (Note: Links have been removed),

A simulacrum (plural: simulacra from Latin: simulacrum, which means “likeness, similarity”), is a representation or imitation of a person or thing.[1] The word was first recorded in the English language in the late 16th century, used to describe a representation, such as a statue or a painting, especially of a god. By the late 19th century, it had gathered a secondary association of inferiority: an image without the substance or qualities of the original.[2] Philosopher Fredric Jameson offers photorealism as an example of artistic simulacrum, where a painting is sometimes created by copying a photograph that is itself a copy of the real.[3] Other art forms that play with simulacra include trompe-l’œil,[4] pop art, Italian neorealism, and French New Wave.[3]

Philosophy

The simulacrum has long been of interest to philosophers. In his Sophist, Plato speaks of two kinds of image making. The first is a faithful reproduction, attempted to copy precisely the original. The second is intentionally distorted in order to make the copy appear correct to viewers. He gives the example of Greek statuary, which was crafted larger on the top than on the bottom so that viewers on the ground would see it correctly. If they could view it in scale, they would realize it was malformed. This example from the visual arts serves as a metaphor for the philosophical arts and the tendency of some philosophers to distort truth so that it appears accurate unless viewed from the proper angle.[5] Nietzsche addresses the concept of simulacrum (but does not use the term) in the Twilight of the Idols, suggesting that most philosophers, by ignoring the reliable input of their senses and resorting to the constructs of language and reason, arrive at a distorted copy of reality.[6]

Postmodernist French social theorist Jean Baudrillard argues that a simulacrum is not a copy of the real, but becomes truth in its own right: the hyperreal. Where Plato saw two types of representation—faithful and intentionally distorted (simulacrum)—Baudrillard sees four: (1) basic reflection of reality; (2) perversion of reality; (3) pretence of reality (where there is no model); and (4) simulacrum, which “bears no relation to any reality whatsoever”.[7] In Baudrillard’s concept, like Nietzsche’s, simulacra are perceived as negative, but another modern philosopher who addressed the topic, Gilles Deleuze, takes a different view, seeing simulacra as the avenue by which an accepted ideal or “privileged position” could be “challenged and overturned”.[8] Deleuze defines simulacra as “those systems in which different relates to different by means of difference itself. What is essential is that we find in these systems no prior identity, no internal resemblance”.[9]

Getting back to the proposed research, an Oct. (?), 2015 University of North Carolina news release, which originated the news item, describes the proposed work in more detail,

Allbritton is an expert at microfabrication and microengineering. Also on the team are intestinal stem cell expert Scott T. Magness, associate professor of medicine, biomedical engineering, and cell and molecular physiology in the UNC School of Medicine; microbiome expert Scott Bultman, associate professor of genetics in the UNC School of Medicine; and bioinformatics expert Shawn Gomez, associate professor of biomedical engineering in UNC’s College of Arts and Sciences and NC State.

The impetus for the “organ-on-chip” movement comes largely from the failings of the pharmaceutical industry. For just a single drug to go through the discovery, testing, and approval process can take as many as 15 years and as much as $5 billion dollars. Animal models are expensive to work with and often don’t respond to drugs and diseases the same way humans do. Human cells grown in flat sheets on Petri dishes are also a poor proxy. Three-dimensional “organoids” are an improvement, but these hollow balls are made of a mishmash of cells that doesn’t accurately mimic the structure and function of the real organ.

Basically, the human gut is a 30-foot long hollow tube made up of a continuous single-layer of specialized cells. Regenerative stem cells reside deep inside millions of small pits or “crypts” along the tube, and mature differentiated cells are linked to the pits and live further out toward the surface. The gut also contains trillions of microbes, which are estimated to outnumber human cells by ten to one. These diverse microbial communities – collectively known as the microbiota – process toxins and pharmaceuticals, stimulate immunity, and even release hormones to impact behavior.

To create a dime-sized version of this complex microenvironment, the UNC-NC State team borrowed fabrication technologies from the electronics and microfluidics world. The device is composed of a polymer base containing an array of imprinted or shaped “hydrogels,” a mesh of molecules that can absorb water like a sponge. These hydrogels are specifically engineered to provide the structural support and biochemical cues for growing cells from the gut. Plugged into the device will be various kinds of plumbing that bring in chemicals, fluids, and gases to provide cues that tell the cells how and where to differentiate and grow. For example, the researchers will engineer a steep oxygen gradient into the device that will enable oxygen-loving human cells and anaerobic microbes to coexist in close proximity.

“The underlying concept – to simply grow a piece of human tissue in a dish – doesn’t seem that groundbreaking,” said Magness. “We have been doing that for a long time with cancer cells, but those efforts do not replicate human physiology. Using native stem cells from the small intestine or colon, we can now develop gut tissue layers in a dish that contains stem cells and all the differentiated cells of the gut. That is the thing stem cell biologists and engineers have been shooting for, to make real tissue behave properly in a dish to create better models for drug screening and cell-based therapies. With this work, we made a big leap toward that goal.”

Right now, the team has a working prototype that can physically and chemically guide mouse intestinal stem cells into the appropriate structure and function of the gut. For several years, Magness has been isolating and banking human stem cells from samples from patients undergoing routine colonoscopies at UNC Hospitals.

As part of the grant, he will work with the rest of the team to apply these stem cells to the new device and create “simulacra” that are representative of each patient’s individual gut. The approach will enable researchers to explore in a personalized way how both the human and microbial cells of the gut behave during healthy and diseased states.

“Having a system like this will advance microbiota research tremendously,” said Bultman. “Right now microbiota studies involve taking samples, doing sequencing, and then compiling an inventory of all the microbes in the disease cases and healthy controls. These studies just draw associations, so it is difficult to glean cause and effect. This device will enable us to probe the microbiota, and gain a better understanding of whether changes in these microbial communities are the cause or the consequence of disease.”

I wish them good luck with their work and to end on another interesting note, the concept of organs-on-a-chip won a design award. From a June 22, 2015 article by Oliver Wainwright for the Guardian (Note: Links have been removed),

Meet the Lung-on-a-chip, a simulation of the biological processes inside the human lung, developed by the Wyss Institute for Biologically Inspired Engineering at Harvard University – and now crowned Design of the Year by London’s Design Museum.

Lined with living human cells, the “organs-on-chips” mimic the tissue structures and mechanical motions of human organs, promising to accelerate drug discovery, decrease development costs and potentially usher in a future of personalised medicine.

“This is the epitome of design innovation,” says Paola Antonelli, design curator at New York’s Museum of Modern Art [MOMA], who nominated the project for the award and recently acquired organs-on-chips for MoMA’s permanent collection. “Removing some of the pitfalls of human and animal testing means, theoretically, that drug trials could be conducted faster and their viable results disseminated more quickly.”

Whodathunkit? (Tor those unfamiliar with slang written in this form: Who would have thought it?)

Ideas becoming knowledge: interview with Dr. Rainer Becker (part 1 of 2)

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ETA Mar. 11, 2013: I was notified by Rainer Becker that his participation was cancelled and the organizers took the project in another direction. Consequently, much of what follows is no longer relevant. However, the discussion about knowledge and ideas and Becker’s theorists may be of some interest.

I’m very pleased to publish this interview (part 1 today) with Dr. Rainer Becker on a topic (how an idea becomes knowledge in the field of science) that has long interested me. First, some information about the research project and Dr. Becker from the April 22, 2010 news item on Nanowerk,

How do sensational ideas become commonly accepted knowledge? How does a hypothesis turn into certainty? What are the ways and words that bring results of scientific experiments into textbooks and people’s minds, how are they “transferred” into these domains? Science philosopher Dr. Rainer Becker has recently started dealing with such questions. Over the next three years, Becker will accompany the work of Professor Dr. Frank Rösl’s department at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), which studies cancer-causing viruses. He is one of three scientists in an interdisciplinary joint project which is funded by the German Ministry of Education and Research (BMBF) with a total sum of approximately € 790,000.

…

Becker’s mission in Heidelberg is part of a research project entitled “Transfer knowledge – knowledge transfer. About the past and present of the transfer between life sciences and humanities.” The project is carried out by DKFZ jointly with the Center for Literary and Cultural Studies (Zentrum für Literatur- und Kulturforschung, ZfL) in Berlin. Project leaders are Professor Dr. Frank Rösl of DKFZ and Dr. Falko Schmieder of ZfL. It comprises three individual projects in which forms of knowledge transfer related to three different constellations of science history are studied in a cultural-scientific approach.

Dr. Becker’s project,

The third and final project, which is pursued by Rainer Becker at DKFZ, deals with the question of the relevance of current knowledge concepts such as the one that understands and experimentally studies cancer as a consequence of viral infections.

“I am pleased that we will explore the relevance of tumor virology across disciplinary borders and I hope we will gain fundamental insights into how scientific discourses develop and how they are ultimately accepted in scientific thought collectives,” said departmental head Frank Rösl about the relevance of the current project.

This is not Dr. Becker’s first such project, his doctoral thesis touched on some of the same themes of how scientific discourse develops,

Rainer Becker wrote his doctoral thesis while he was employed at the Institute of Philosophy of Darmstadt Technical University. There he made parallel studies of the social history of the computer and the “universal science” of cybernetics. Back then he already chose a topic that transcends borders between humanities and natural sciences. “While I was working on my doctoral thesis, I explored the question of ‘transfers’ – namely between technology, natural sciences and philosophy in the 1940s: The development of computers and cybernetics would not have been possible without prior conceptual and metaphorical ‘transfers’ between life sciences and technical sciences.”

In his future project, the philosopher will study in real time, so to speak, how natural science data are being obtained, processed and communicated. As a “researcher of science”, he will observe the laboratory work from the perspective of the humanities and cultural science, he will do research in archives and will interview scientists. It is for good reason that the project is located at DKFZ, because this is the place where findings from basic biological research become relevant for medicine and the public. Thus, the Nobel Prize-winning discovery by DKFZ’s former Scientific Director, Professor Harald zur Hausen, that particular viruses cause cervical cancer has led to a vaccine against this type of cancer.

Now for the interview:

1. First, congratulations on receiving funding for such a fascinating line of query. When does the project start and what is the period of time during which it will run?

A: Indeed, the funding delighted all of us. My sub-project in Heidelberg started in late October 2009, it will be supported for 3 years.

2. Will you be working alone or will you be working with an interdisciplinary team?

A: Currently I am doing my study in Heidelberg on my own, getting assisted locally by one of the project leaders, a biologist highly interested in interdisciplinary work: Prof. Frank Roesl, head of the department where I am doing my research. The other project leader, Dr. Falko Schmieder and two other science philosophers support me in Berlin, at the Center for Literary and Cultural Research (ZfL). Like me, both of them work on their own sub-projects while getting support by Dr. Schmieder: he does ensure the convergence of the sub-projects. We discuss the topics during our regular meetings – but also via email, skype, wikis for sharing documents etc.

Because the main focus of the project is historical, both of the other sub-projects work –like me in the past – in a more historical way: they try to elucidate the current situation in the Heidelberg lab of 2010 – molecular biological work on supposedly tumourgenic viruses – by working in archives, on in part comparable fields, but different time scales: (a) Dr. Birgit Griesecke – mainly doing studies on Ludwig Fleck – is working on the 1930s, (b) PD Dr. Peter Berz – researching contexts esp. around Jacques Monod – is working on the 1970s. Both help me to understand the current scientific situation in the corresponding historical context.

We also try to get additional funding options for one or two other researchers (e.g. sociologists, communication scientists) supporting our work in a interdisciplinary way.

3. Are there any theorists that have influenced how you are approaching this project?

A: The whole project is closely related to the work of the Polish bacteriologist and sociologist of science Ludwig Fleck. Its main theoretical references point to him – by as well trying to ‘refresh’ his approaches in ways more adequate to the current scientific situation: not only everything that happened after the ‘linguistic turn’ and all the concerns on ‘media’, but also dealing with questions on the significance of ‘things’ in the labs around 2010. This confrontation of Fleck with the present research raises several questions, for example:

Do apparatuses reflect or even materialize special sorts of scientific ‘thought-styles’?

Do specific ‘thought-collectives’ gather or even get constituted around special lab equipments to what extent do they form prior styles of thinking – what kind of ‘migration-background’ has each ‘thing’ with what implications and what styles of local adoption?

What exactly is the correlation between assemblages of things, humans, animals, discourses and what Mary Douglas coined ‘worlds of thought’ – and their inhabitants / participants?

What is their contribution to the specific local – and the same time globally connected – scientific way of worldmaking (in the field of cancer research)?

What political implications potentially are embedded in all that fields – from specific ways of problematisation to its effects?

My own theoretical background was mainly influenced by the philosophical tradition of structuralism and so called ‘post-structuralism’, especially Michel Foucault – so phenomenological traditions also interest me. Foucault, Gilles Deleuze, J.-F. Lyotard, M. Serres and M. de Certeau framed my more traditional approaches to political philosophy on the one hand (from Plato, Hobbes, Kant, Nietzsche, Weber, Arendt to the early/middle Frankfurt School, French Postmodernist to current debates on ‘radical democratic’-thinkers as well as philosophical experiments like tiqqun) but on the same time on the other hand to different fields of knowledge, esp. concerning the relation technology – art – bios (I wrote my dissertation on a ‘coevolutionary’ history of the ‚universal machine’/ computers and ‘first’ cybernetics in connection to what Foucault termed ‘biopower’ – coming from Canguilhem and handing this concept over to E. Fox-Keller, I. Hacking, D. Haraway and L. Kay).

In my field, a biological laboratory dealing with viruses and cancer, Michel Serres’ thoughts on different phenomena of ‘inbetween’/’3rds’ as well as Foucault’s spatial approaches in their connection to knowledge/power (heterotopia, taxonomy/order, diagrams like ‘panoptism’) currently form reflections of my experiences more and more – as well as my contention with prominent ‘first wave’ researchers in the field of science/laboratory studies, e.g. B. Latour (esp. the ‘early’), K. Knorr-Cetina, H.J. Rheinberger (esp. beyond his Heidegger-References), P. Rabinow (both theoretical and practical work) and D. Haraway (esp. ‘when species meet’), flanked by what could be coined a wide field of ethnology in the broadest sense (C. Lèvi-Strauss, M. Douglas, C. Geertz, E. Goffman): ethnology of the own, western culture interested me since my first contacts with poststructuralism/Nietzsche. In that range, scientific and everyday practices and their relation to ‘strangeness’ of the field (for the lab-practitioners, for me) more and more comes to focus (think of the concept of ‘problematisation’) – and also theorist of  ‘practice’ keep framing my attention (A. Pickering, K. Sunder-Rajan, M. de Certeau). I hope the projects (my colleagues and mine) will contribute something at least in that latter field.

4. The description in the press release for how you plan to go about your project reminded me of Bruno Latour’s Laboratory Life where he described the creation of a ‘scientific fact’. Obviously you won’t be repeating that work, so I’m wondering if you could describe your process and goals in more detail.

see (3)

Tomorrow: more details about the project and how the research will be disseminated.