Tag Archives: Michelle Oyen

Scientists hunger for your money

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Crowdfunding (raising funds by posting a project, on a website designed for the purpose, and asking for money in return for rewards you will give to the funders) seems to be everywhere at the moment. I tried it last year for one of my projects and had one failure and one partial success. It’s certainly an interesting process to go through and I’m fascinated with the current interest from scientists. According to an April 25, 2012 posting by Michael Ho on Techdirt, there are at least four crowdfunding websites for science projects.

In addition to the ones Ho cites, I found the #SciFund Challenge, which is being held from May 1  – May 31, 2012. From their home page,

Last fall, scientists raised $76,230 for their research in the first round of the #SciFund Challenge. The second round launches on May 1, 2012!

What? The #SciFund Challenge is a grand experiment in science funding. Can scientists raise money for their research by convincing the general public to open their wallets for small-amount donations? In more and more fields – from music to dance to journalism – people are raising lots of money for projects in precisely this way. The process is called crowdfunding. The first round of the #SciFund Challenge showed that this model can work for funding scientific research. Now, let’s take it to the next level!

Who? Well over 140 scientists, from across the globe, have signed for the second round of the #SciFund Challenge.

When? From May 1- May 31, 2012, scientists participating in the #SciFund Challenge will each conduct their own crowdfunding campaigns for their own research. But even though each scientist will be fundraising for their own research, participants won’t be on their own.  In the month of April, #SciFund scientists will be trained how to run a crowdfunding campaign. And, through the Challenge, participants will be connected together to increase the chances that everyone succeeds.

How do I learn more? Read the blog! You can also contact one of the #SciFund Challenge organizers with any questions: Jai Ranganathan (jai.ranganathan@gmail.com). If you would like to be informed about future rounds of the #SciFund Challenge, please sign up for our mailing list.

From the About page (I have removed several links),

The #SciFund Challenge is an experiment – can scientists use crowdfunding to fund their research? The current rate of funding for science proposals in the U.S. is ~20%. The current rate for crowdfunding statues of RoboCop in Detroit is 135% – to the tune of $67,436. Perhaps Scientists can do better by tapping this reservoir of funds from an interested public. …

The #SciFund Challenge is also a way to get scientists to directly engage with the public. Crowdfunding forces scientists to build public interaction and outreach into their research from day one. It’s a new mechanism to couple science and society, and one that we think has a lot of promise. …

Founders
The founders of the #SciFund Challenge are Dr. Jai Ranganathan  and Dr. Jarrett Byrnes. We are biologists – ecologists, actually – and each spends too much time in the science online scene. Jai ran a weekly science podcast, called Curiouser and Curiouser for Miller-McCune magazine, and Jarrett is the big boss over at the science blog I’m a Chordata! Urochordata! On Twitter, you can find Jai at @jranganathan and jai.ranganathan@gmail.com and Jarrett at @jebyrnes.

On another note and in response to my April 18, 2012 posting about Lego robots being used to grow bones,  I received a notice about a project to raise funds on Kickstarter. As I’m not a Lego afficionado, it took a little digging to figure out the project.

In my April 18, 2012 posting the scientists used a robot that they built with a Lego Mindstorms kit. The beams used to create a base for the robots limit builders and a team from Denmark (Lasse Mogensen and Soren Jensen), which is the home of Lego, have developed a base (a rectangular plate, 21 x 30 holes), which would allow scientists and others to create larger, more robust and complex robots. They call their project, MinuteBot Base,

There are ways to combine the MinuteBot Base plates, which are fully compatible with Lego products, in case a single base does not suffice.

Here’s the MinuteBot Base Kickstarter page where you can find more information and diagrams. The group has raised almost 1/2 of the funds they’ve requested with some 20 days left in their campaign. The group has contacted Michelle Oyen, who’s one of the scientists cited in my April 18, 2012 posting (from their April 25, 2012 email to me),

We are in contact with Michelle Oyen who expressed interest in our products:

“Please let me know if I can be of use in the future, and if you are interested in collaborating on more ideas regarding using Lego Mindstorms for biomedical/bioengineering research!”

The group also has a second project, a MinuteBot Bearing, which they (represented by team member, Dorota Sauer)  have entered in a contest for a prize of $10,000. From the MinuteBot Bearing page on the Boca Bearing contest website,

What was your goal in building this project?

To design a turntable with a perfect interface with LEGO Mindstorms and with improved mechanical properties. The broader vision is to make a kit consisting of robust elements designed for higher precision and durability using industrial components. Robotics made in minutes. That’s MinuteBot.

Does your project help to solve a problem? If so what problem?

LEGO Mindstorms is very easy to program but as it is a toy the precision, durability and mechanical integrity is limited. The MinuteBot Bearing is based on industry-grade ball bearings providing the needed mechanical performance of the turntable.

What makes your idea unique?

The combination of user friendliness, the interface with LEGO Mindstorms and the good mechanical performance makes MinuteBot Bearing unique.

You can find out more information about the team and the products at the MinuteBot website.

Getting back to Michael Ho and his posting about the science-specific crowdfunding sites, here are two listings I’ve excerpted from his April 25, 2012 posting,

Good luck to them all!

 

Scientists use Lego toys to grow bones

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Dr. Michelle Oyen, team leader and lecturer in the engineering department [Cambridge University, UK], added: “Research is a funny thing because you might think that we order everything up from scientific catalogues – but actually a lot of the things we use around the lab are household items, things that we picked up at the local home goods store – so our Lego robots just fit in with that mind-set.”

That was from the March 28, 2012 news item (Growing bones with Lego) on physorg.com. Oyen’s group at Cambridge University uses the robots to grow synthetic bones as they discuss in this video (from the Cambridge University webpage hosting the March 27, 2012 news release about Lego robots in the lab [it was part of a Google Science Fair promotion],

Here’s a bit more about the robots and about the team’s bone project (from the Cambridge University news release),

 “To make the bone-like substance you take a sample, then you dip it into one beaker of calcium and protein, then rinse it in some water and dip in into another beaker of phosphate and protein – you have to do it over and over and over again to build up the compound, [as seen in the video]” says Daniel Strange, one of the PhD students working on the research.

…

After a bit of investigation the researchers decided to build cranes from a Lego Mindstorms robotics kit, which contains microprocessors, motors, and sensors that can be programmed to perform basic tasks on repeat. The sample is tied to string at the end of the crane which then dips it in the different solutions.

The team quickly discovered that the miniature machines made from the famous plastic blocks vastly reduced the human time cost of creating the bone samples: “the great thing about the robots is once you tell them what to do they can do it very precisely over and over again – so a day later I can come back and see a fully made sample,” says Strange.

…

Bone defects can result from trauma, infection and the removal of tumours, and beyond a certain size of trauma bone is unable to regenerate itself. Current treatments include bone grafts, which can be risky and greatly increase recovery time.

The team at Cambridge are working on hydroxyapatite–gelatin composites to create synthetic bone, and the work is generating considerable interest due to the low energy costs and improved similarity to the tissues they are intended to replace.

Oyen and Strange have published a paper (behind a paywall), Biomimetic bone-like composites fabricated through an automated alternate soaking process, about their biomimetic work and attempts to create scaffolding (synthetic bone) in the journal Acta Biomaterialia. Here’s the abstract,

Hydroxyapatite–gelatin composites have been proposed as suitable scaffolds for bone and dentin tissue regeneration. There is considerable interest in producing these scaffolds using biomimetic methods due to their low energy costs and potential to create composites similar to the tissues they are intended to replace. Here an existing process used to coat a surface with hydroxyapatite under near physiological conditions, the alternate soaking process, is modified and automated using an inexpensive “off the shelf” robotics kit. The process is initially used to precipitate calcium phosphate coatings. Then, in contrast to previous utilizations of the alternate soaking process, gelatin was added directly to the solutions in order to co-precipitate hydroxyapatite–gelatin composites. Samples were investigated by Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy and nanoindentation. Calcium phosphate coatings formed by the alternate soaking process exhibited different calcium to phosphate ratios, with correspondingly distinct structural morphologies. The coatings demonstrated an interconnected structure with measurable mechanical properties, even though they were 95% porous. In contrast, hydroxyapatite–gelatin composite coatings over 2 mm thick could be formed with little visible porosity. The hydroxyapatite–gelatin composites demonstrate a composition and mechanical properties similar to those of cortical bone.