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The Canadian nano scene as seen by the OECD (Organization for Economic Cooperation and Development)

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I’ve grumbled more than once or twice about the seemingly secret society that is Canada’s nanotechnology effort (especially health, safety, and environment issues) and the fact that I get most my information from Organization for Economic Cooperation and Development (OECD) documents. That said, thank you to Lynne Bergeson’s April 8, 2016 post on Nanotechnology Now for directions to the latest OECD nano document,

The Organization for Economic Cooperation and Development recently posted a March 29, 2016, report entitled Developments in Delegations on the Safety of Manufactured Nanomaterials — Tour de Table. … The report compiles information, provided by Working Party on Manufactured Nanomaterials (WPMN) participating delegations, before and after the November 2015 WPMN meeting, on current developments on the safety of manufactured nanomaterials.

It’s an international roundup that includes: Australia, Austria, Belgium, Canada, Germany, Japan, Korea, the Netherlands, Switzerland, Turkey, United Kingdom, U.S., and the European Commission (EC), as well as the Business and Industry Advisory Committee to the OECD (BIAC) and International Council on Animal Protection in OECD Programs (ICAPO).

As usual, I’m focusing on Canada. From the DEVELOPMENTS IN DELEGATIONS ON THE SAFETY OF MANUFACTURED NANOMATERIALS – TOUR DE TABLE Series on the Safety of Manufactured Nanomaterials No. 67,

CANADA
National  developments  on  human  health  and  environmental  safety  including  recommendations, definitions, or discussions related to adapting or applying existing regulatory systems or the drafting of new laws/ regulations/amendments/guidance materials A consultation document on a Proposed Approach to Address Nanoscale Forms of Substances on the Domestic  Substances  List was  published  with  a  public  comment  period  ending on  May  17,  2015. The proposed approach outlines the Government’s plan to address nanomaterials considered in commerce in Canada (on  Canada’s  public inventory).  The  proposal is a stepwise  approach to  acquire  and  evaluate information,  followed  by  any  necessary  action. A  follow-up  stakeholder  workshop  is  being  planned  to discuss  next  steps  and  possible  approaches  to prioritize  future  activities. The  consultation document  is available at: http://www.ec.gc.ca/lcpe-cepa/default.asp?lang=En&n=1D804F45-1

A mandatory information gathering survey was published on July 25, 2015. The purpose of the survey is to collect information to determine the commercialstatus of certain nanomaterials in Canada. The survey targets  206  substances  considered  to  be  potentially  in commerce  at  the  nanoscale. The  list  of  206 substances was developed using outcomes from the Canada-United States Regulatory Cooperation Council (RCC)  Nanotechnology  Initiative  to  identify nanomaterial  types. These  nanomaterial  types  were  cross-referenced  with  the Domestic  Substances  List to  develop  a  preliminary  list  of  substances  which are potentially intentionally manufactured at the nanoscale. The focus of the survey aligns with the Proposed Approach to  Address  Nanoscale  Forms  of  Substances  on  the Domestic  Substances  List (see  above)  and certain  types  of  nanomaterials  were  excluded  during the  development  of  the  list  of  substances. The information  being  requested  by  the  survey  includes substance  identification,  volumes,  and  uses.  This information will feed into the Government’s proposed approach to address nanomaterials on the Domestic Substances List. Available at: http://gazette.gc.ca/rp-pr/p1/2015/2015-07-25/html/notice-avis-eng.php

Information on:

a.risk  assessment  decisions, including  the  type  of:  (a)  nanomaterials  assessed; (b) testing recommended; and (c) outcomes of the assessment;

Four substances were notified to the program since the WPMN14 – three surface modified substances and  one  inorganic  substance.  No  actions,  including  additional  data requests,  were  taken  due  to  low expected  exposures  in  accordance  with  the New  Substances  Notifications  Regulations  (Chemicals and Polymers) (NSNR) for two of the substances.  Two of the substances notified were subject to a Significant New Activity Notice. A Significant New Activity notice is an information gathering tool used to require submission  of  additional  information  if  it  is suspected  that  a  significant  new  activity  may  result in  the substance becoming toxic under the Canadian Environmental Protection Act, 1999.

b.Proposals, or modifications to previous regulatory decisions

As  part  of  the  Government’s  Chemicals  Management Plan,  a  review  is  being  undertaken  for  all substances  which  have  been  controlled through  Significant  New  Activity  (SNAc)  notices (see  above).  As part  of  this  activity,  the  Government  is  reviewing past  nanomaterials  SNAc  notices  to  see  if  new information  is  available  to  refine  the  scope  and information  requirements.    As  a  result  of  this  review, 9 SNAc  notices  previously  in  place  for  nanomaterials have  been  rescinded.    This  work  is  ongoing,  and  a complete review of all nanomaterial SNAcs is currently planned to be completed in 2016.

Information related to good practice documents

The Canada-led,  ISO  standards project, ISO/DTR  19716 Nanotechnologies — Characterization  of cellulose  nanocrystals, [emphasis mine] initiated  in  April 2014, is  now at Committee  Draft  (CD)  3-month  ISO ballot, closing    Aug 31, 2015. Ballot comments will be addressed during JWG2 Measurement and Characterization working  group meetings  at  the 18th Plenary  of  ISO/TC229, Nanotechnologies,  being held in Edmonton, Alberta, Sep. 28 – Oct. 2, 2015.

Research   programmes   or   strategies   designed   to  address   human   health   and/   or environmental safety aspects of nanomaterials

Scientific research

Environment Canada continues to support various academic and departmental research projects. This research has to date included studying fate and effects of nanomaterials in the aquatic, sediment, soil, and air  compartments. Funding  in  fiscal  2015-16  continues  to  support  such  projects,  including  sub-surface transportation, determining key physical-chemical parameters to predict ecotoxicity, and impacts of nano-silver [silver nanoparticles]  addition  to  a  whole  lake  ecosystem [Experimental Lakes Area?]. Environment  Canada  has  also  partnered  with  the National Research  Council  of  Canada  recently  to  initiate  a project  on  the  development  of  test  methods  to identify surfaces of nanomaterials for the purposes of regulatory identification and to support risk assessments. In addition,  Environment  Canada  is  working  with  academic laboratories in  Canada  and  Germany  to  prepare guidance to support testing of nanoparticles using the OECD Test Guideline for soil column leaching.

Health  Canada  continues  its  research  efforts  to  investigate  the  effects  of  surface-modified  silica nanoparticles. The   aims   of   these   projects   are  to:   (1) study the importance of size and surface functionalization;  and  (2)  provide a genotoxic profile and  to  identify  mechanistic  relationships  of  particle properties  to  elicited  toxic  responses.  A manuscript reporting  the in  vitro genotoxic,  cytotoxic and transcriptomic  responses  following  exposure  to  silica  nanoparticles  has  recently  been  submitted to  a  peer reviewed journal and is currently undergoing review. Additional manuscripts reporting the toxicity results obtained to date are in preparation.

Information on public/stakeholder consultations;

A consultation document on a Proposed Approach to Address Nanoscale Forms of Substances on the Domestic  Substances  List was  published  with a  public  comment  period ending  on May  17,  2015  (see Question  1).  Comments  were  received  from approximately  20  stakeholders  representing  industry and industry  associations,  as  well  as  non-governmental  organizations. These  comments  will  inform  decision making to address nanomaterials in commerce in Canada.

Information on research or strategies on life cycle aspects of nanomaterials

Canada, along with Government agencies in the United States, Non-Governmental Organizations and Industry,  is  engaged  in  a  project  to  look  at releases  of  nanomaterials  from  industrial  consumer  matrices (e.g., coatings). The objectives of the NanoRelease Consumer Products project are to develop protocols or
methods (validated  through  interlaboratory  testing) to  measure  releases  of  nanomaterials  from  solid matrices as a result of expected uses along the material life cycle for consumer products that contain the nanomaterials. The  project  is  currently  in  the  advanced  stages  of Phase  3  (Interlaboratory  Studies).  The objectives of Phase 3 of the project are to develop robust methods for producing and collecting samples of CNT-epoxy  and  CNT-rubber  materials  under  abrasion  and  weathering scenarios,  and  to  detect  and quantify, to the extent possible, CNT release fractions. Selected laboratories in the US, Canada, Korea and the European Community are finalising the generation and analysis of sanding and weathering samples and the    results    are    being    collected    in    a   data    hub    for    further    interpretation    and    analysis.

Additional details about the project can be found at the project website: http://www.ilsi.org/ResearchFoundation/RSIA/Pages/NanoRelease1.aspx

Under the OECD Working Party on Resource Productivity and Waste (WPRPW), the expert group on waste containing nanomaterials has developed four reflection papers on the fate of nanomaterials in waste treatment  operations.  Canada  prepared the  paper  on  the  fate  of  nanomaterials in  landfills;  Switzerland on the  recycling  of  waste  containing  nanomaterials;  Germany  on  the  incineration  of  waste  containing nanomaterials;  and  France  on  nanomaterials  in wastewater  treatment.  The  purpose  of  these  papers is to provide  an  overview  of  the  existing  knowledge  on the  behaviour  of  nanomaterials  during  disposal operations and identify the information gaps. At the fourth meeting of the WPRPW that took place on 12-14 November 2013, three of the four reflection papers were considered by members. Canada’s paper was presented and discussed at the fifth meeting of the WPRPRW that took place on 8-10 December 2014. The four  papers  were  declassified  by  EPOC  in  June  2015, and  an  introductory  chapter  was  prepared  to  draw these  papers  together. The introductory  chapter  and accompanying  papers  will  be  published in  Fall  2015. At  the sixth  meeting  of  the  WPRPW  in  June – July  2015,  the  Secretariat  presented  a  proposal  for an information-sharing  platform  that  would  allow  delegates  to  share research  and  documents  related  to nanomaterials. During a trial phase, delegates will be asked to use the platform and provide feedback on its use at the next meeting of the WPRPW in December 2015. This information-sharing platform will also be accessible to delegates of the WPMN.

Information related to exposure measurement and exposure mitigation.

Canada and the Netherlands are co-leading a project on metal impurities in carbon nanotubes. A final version  of  the  report  is  expected  to  be ready for WPMN16. All  research has  been completed (e.g. all components are published or in press and there was a presentation by Pat Rasmussen to SG-08 at the Face-to-Face Meeting in Seoul June 2015). The first draft will be submitted to the SG-08 secretariat in autumn 2015. Revisions  will  be  based  on  early  feedback  from  SG-08  participants.  The  next  steps  depend  on  this feedback and amount of revision required.

Information on past, current or future activities on nanotechnologies that are being done in co-operation with non-OECD countries.

A webinar between ECHA [European Chemicals Agency], the US EPA [Environmental Protection Agency] and Canada was hosted by Canada on April 16, 2015. These are  regularly  scheduled  trilateral  discussions  to keep  each  other  informed  of  activities  in  respective jurisdictions.

In  March 2015, Health  Canada  hosted  3  nanotechnology knowledge  transfer sessions  targeting Canadian  government  research  and  regulatory  communities  working  in  nanotechnology.  These  sessions were  an  opportunity  to  share  information  and perspectives  on  the  current  state  of  science supporting  the regulatory  oversight  of  nanomaterials with  Government.  Presenters  provided  detailed  outputs  from  the OECD WPMN including: updates on OECD test methods and guidance documents; overviews of physical-chemical properties, as well as their relevance to toxicological testing and risk assessment; ecotoxicity and fate   test   methods;   human   health   risk   assessment   and   alternative   testing   strategies;   and exposure measurement  and  mitigation.  Guest  speakers  included  Dr  Richard  C.  Pleus  Managing  Director  and  Director of Intertox, Inc and Dr. Vladimir Murashov Special Assistant on Nanotechnology to the Director of National Institute for Occupational Safety and Health (NIOSH).

On   March   4-5, 2015, Industry   Canada   and   NanoCanada co-sponsored  “Commercializing Nanotechnology  in  Canada”,  a  national  workshop  that brought  together  representatives  from  industry, academia and government to better align Canada’s efforts in nanotechnology.  This workshop was the first of  its  kind  in  Canada. It  also  marked  the  official  launch  of  NanoCanada (http://nanocanada.com/),  a national  initiative  that  is  bringing  together stakeholders  from  across  Canada  to  bridge  the  innovation  gap and stimulates emerging technology solutions.

It’s nice to get an update about what’s going on. Despite the fact this report was published in 2016 the future tense is used in many of the verbs depicting actions long since accomplished. Maybe this was a cut-and-paste job?

Moving on, I note the mention of the Canada-led,  ISO  standards project, ISO/DTR  19716 Nanotechnologies — Characterization  of cellulose  nanocrystals (CNC). For those not familiar with CNC, the Canadian government has invested hugely in this material derived mainly from trees, in Canada. Other countries and jurisdictions have researched nanocellulose derived from carrots, bananas, pineapples, etc.

Finally, it was interesting to find out about the existence of  NanoCanada. In looking up the Contact Us page, I noticed Marie D’Iorio’s name. D’Iorio, as far as I’m aware, is still the Executive Director for Canada’s National Institute of Nanotechnology (NINT) or here (one of the National Research Council of Canada’s institutes). I have tried many times to interview someone from the NINT (Nils Petersen, the first NINT ED and Martha Piper, a member of the advisory board) and more recently D’Iorio herself only to be be met with a resounding silence. However, there’s a new government in place, so I will try again to find out more about the NINT, and, this time, NanoCanada.

Part 2 (b) of 3: Science Culture: Where Canada Stands; an expert assessment (reconstructed)

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Carrying on from part 2 (a) of this commentary on the Science Culture: Where Canada Stands assessment by the Council of Canadian Academies (CAC).

One of the most intriguing aspects of this assessment was the reliance on an unpublished inventory of Canadian science outreach initiatives (informal science education) that was commissioned by the Korean Foundation for the Advancement of Science and Creativity,

The system of organizations, programs, and initiatives that supports science culture in any country is dynamic. As a result, any inventory provides only a snapshot at a single point in time, and risks quickly becoming out of date. No sustained effort has been made to track public science outreach and engagement efforts in Canada at the national or regional level. Some of the Panel’s analysis relies on data from an unpublished inventory of public science communication initiatives in Canada undertaken in 2011 by Bernard Schiele, Anik Landry, and Alexandre Schiele for the Korean Foundation for the Advancement of Science and Creativity (Schiele et al., 2011). This inventory identified over 700 programs and organizations across all provinces and regions in Canada, including over 400 initiatives related to museums, science centres, zoos, or aquariums; 64 associations or NGOs involved in public science outreach; 49 educational initiatives; 60 government policies and programs; and 27 media programs. (An update of this inventory completed by the Panel brings the total closer to 800 programs.) The inventory is used throughout the chapter [chapter five] to characterize different components of the Canadian system supporting public science outreach, communication, and engagement. (p. 130 PDF; p. 98 print)

I’m fascinated by the Korean interest and wonder if this due to perceived excellence or to budgetary considerations. The cynic in me suspects the Korean foundation was interested in the US scene but decided that information from the Canadian scene would be cheaper to acquire and the data could be extrapolated to give a perspective on the US scene.

In addition to the usual suspects (newspapers, television, radio, science centres, etc.), the Expert Panel did recognize the importance of online science sources (they would have looked foolish if they hadn’t),

Canadians are increasingly using the internet to seek out information relating to science. This activity can take the form of generalized searches about science-related issues or more targeted forms of information acquisition. For example, Canadians report using the internet to seek out information on health and medical issues an average of 47 times a year, or nearly every week. Other forms of online exposure to scientific content also appear to be common. For example, 46% of Canadians report having read a blog post or listserv related to science and technology at least once in the last three months, and 62% having watched an online video related to science and technology.

An increasing reliance on the internet as the main source of information about science and technology is consistent with the evolution of the media environment, as well as with survey data from other countries. Based on the Panel’s survey, 17% of Canadians, for example, report reading a printed newspaper daily, while 40% report reading about the news or current events online every day. (p. 13/2 PDF; p. 100/1 print)

In common with the rest of the world, Canadians are producing and enjoying science festivals,

In Canada there are two established, large-scale science festivals. Science Rendezvous [founded in 2008 as per its Wikipedia entry] takes place in about 20 cities across the country and combines a variety of programming to comprise a day-long free event (Science Rendezvous, 2013).

The annual Eureka! Festival in Montréal (see Figure 5.6 [founded in 2007 as per its program list]) has over 100 activities over three days; it attracted over 68,000 attendees in 2012 (Eureka! Festival, 2013). More science festivals have recently been created. The University of Toronto launched the Toronto Science Festival in fall 2013 (UofT, 2013), and Beakerhead, a new festival described as a “collision of art and culture, technology, and engineering,” was launched in 2013 in Calgary (Beakerhead, 2013). Two Canadian cities have also recently won bids to host STEMfest (Saskatoon in 2015 and Halifax in 2018), an international festival of science, technology, engineering, and mathematics (Global STEM States, 2014). (pp. 145/6 PDF; pp. 113/4 PDF)

The assessment notes have a grand total of five radio and television programmes devoted to science: The Nature of Things, Daily Planet, Quirks and Quarks, Découverte, and Les années lumière (p. 150 PDF; p. 118 print) and a dearth of science journalism,

Dedicated science coverage is notably absent from the majority of newspapers and other print journalism in Canada. As shown in Table 5.3, none of the top 11 newspapers by weekly readership in Canada has a dedicated science section, including nationals such as The Globe and Mail and National Post. Nine of these newspapers have dedicated technology sections, which sometimes contain sub-sections with broader coverage of science or environment stories; however, story coverage tends to be dominated by technology or business (or gaming) stories. Few Canadian newspapers have dedicated science journalists on staff, and The Globe and Mail is unique among Canadian papers in having a science reporter, a medicine and health reporter, and a technology reporter. (p. 152 PDF; p. 120 print)

Not stated explicitly in the assessment is this: those science and technology stories you see in the newspaper are syndicated stories, i.e., written by reporters for the Associated Press, Reuters, and other international press organizations or simply reprinted (with credit) from another newspaper.

The report does cover science blogging with this,

Science blogs are another potential source of information about developments in science and technology. A database compiled by the Canadian Science Writers’ Association, as of March of 2013, lists 143 Canadian science blogs, covering all areas of science and other aspects of science such as science policy and science culture (CSWA, 2013). Some blogs are individually authored and administered, while others are affiliated with larger networks or other organizations (e.g., Agence Science-Presse, PLOS Blogs). Canadian science blogger Maryse de la Giroday has also published an annual round-up of Canadian science blogs on her blog (www.frogheart.ca) for the past three years, and a new aggregator of Canadian science blogs was launched in 2013 (www.scienceborealis.ca). [emphases mine]

Data from the Panel’s survey suggest that blogs are becoming a more prominent source of information about science and technology for the general public. As noted at the beginning of the chapter, 46% of Canadians report having read a blog post about science or technology at least once in the past three months. Blogs are also influencing the way that scientific research is carried out and disseminated. A technical critique in a blog post by Canadian microbiologist Rosie Redfield in 2010, for example, catalyzed a widely publicized debate on the validity of a study published in Science, exploring the ability of bacteria to incorporate arsenic into their DNA. The incident demonstrated the potential impact of blogs on mainstream scientific research. CBC highlighted the episode as the Canadian science story of the year (Strauss, 2011), and Nature magazine identified Redfield as one of its 10 newsmakers of the year in 2011 as a result of her efforts to replicate the initial study and publicly document her progress and results (Hayden, 2011).

The impact of online information sources, however, is not limited to blogs, with 42% of Canadians reporting having heard about a science and technology news story though social media sources like Twitter and Facebook in the last three months. And, as noted earlier, the internet is often used to search for information about specific science and technology topics, both for general issues such as climate change, and more personalized information on medical and health issues.(pp. 153/4 PDF; pp. 121/2 print)

Yes, I got a shout out as did Rosie Redfield. We were the only two science bloggers namechecked. (Years ago, the Guardian newspaper was developing a science blog network and the editor claimed he couldn’t find many female science bloggers after fierce criticism of its first list of bloggers. This was immediately repudiated not only by individuals but someone compiled a list of hundreds of female science bloggers.) Still, the perception persists and I’m thrilled that the panel struck out in a different direction. I was also pleased to see Science Borealis (a Canadian science blog aggregator) mentioned. Having been involved with its founding, I’m also delighted its first anniversary was celebrated in Nov. 2014.

I doubt many people know we have a science press organization in Canada, Agence Science-Presse, but perhaps this mention in the assessment will help raise awareness in Canada’s English language media,

Founded in 1978 with the motto Parce que tout le monde s’intéresse à la science (“because everyone is interested in science”), Agence Science-Presse is a not-for-profit organization in Quebec that supports media coverage of science by distributing articles on scientific research or other topical science and technology issues to media outlets in Canada and abroad. The organization also supports science promotion activities aimed at youth. For example, it currently edits and maintains an aggregation of blogs designed for young science enthusiasts and science journalists (Blogue ta science). (p. 154 PDF; p. 122)

The final chapter (the 6th) of the assessment makes five key recommendations for ‘Cultivating a strong science culture’:

  1. Support lifelong science learning
  2. Make science inclusive
  3. Adapt to new technologies
  4. Enhance science communication and engagement
  5. Provide national or regional leadership

Presumably the agriculture reference in the chapter title is tongue-in-cheek. Assuming that’s not one of my fantasies, it’s good to see a little humour.

On to the first recommendation, lifelong learning,

… Science centres and museums, science programs on radio and television, science magazines and journalism, and online resources can all help fulfil this function by providing accessible resources for adult science learning, and by anticipating emerging information needs based on topical issues.

Most informal science learning organizations already provide these opportunities to varying degrees; however, this conception of the relative roles of informal and formal science learning providers differs from the traditional understanding, which often emphasizes how informal environments can foster engagement in science (particularly among youth), thereby triggering additional interest and the later acquisition of knowledge (Miller, 2010b). [emphasis mine] Such a focus may be appropriate for youth programming, but neglects the role that these institutions can play in ongoing education for adults, who often seek out information on science based on specific, well-defined interests or needs (e.g., a medical diagnosis, a newspaper article on the threat of a viral pandemic, a new technology brought into the workplace) (Miller, 2012). [emphases mine] Informal science learning providers can take advantage of such opportunities by anticipating these needs, providing useful and accessible information, and then simultaneously building and deepening knowledge of the underlying science through additional content.

I’m glad to see the interest in adult informal science education although the emphasis on health/medical and workplace technology issues suggests the panel underestimates, despite the data from its own survey, Canadians’ curiosity about and interest in science and technology. The panel also underestimates the tenacity with which many gatekeepers hold to the belief that no one is interested in science. It took me two years before a local organizer would talk to me about including one science-themed meeting in his programme (the final paragraph in my April 14, 2014 post describes some of the process  and my April 18, 2014 post describes the somewhat disappointing outcome). In the end, it was great to see a science-themed ‘city conversation’ but I don’t believe the organizer found it to be a success, which means it’s likely to be a long time before there’s another one.

The next recommendation, ‘Making science inclusive’, is something that I think needs better practice. If one is going to be the change one wants to see that means getting people onto your expert panels that reflect your inclusiveness and explaining to your audience how your expert panel is inclusive.

The ‘Adapting to new technologies’ recommendation is where I expected to see some mention of the social impact of such emerging technologies as robotics, nanotechnology, synthetic biology, etc. That wasn’t the case,

Science culture in Canada and other countries is now evolving in a rapidly changing technological environment. Individuals are increasingly turning to online sources for information about science and technology, and science communicators and the media are also adapting to the new channels of communication and outreach provided over the internet. As people engage more with new forms of technology in their home and work lives, organizations may be able to identify new ways to take advantage of available technologies to support learning and foster science interest and engagement. At the same time, as noted in Chapter 2, this transition is also challenging traditional models of operation for many organizations such as science centres, museums, and science media providers, forcing them to develop new strategies.

Examples of the use of new technologies to support learning are now commonplace. Nesta, an innovation-oriented organization based in the United Kingdom, conducted a study investigating the extent to which new technologies are transforming learning among students (Luckin et al., 2012) (p. 185 PDF; p. 153 print)

Admittedly, the panel was not charged with looking too far into the future but it does seem odd that in a science culture report there isn’t much mention (other than a cursory comment in an early chapter) of these emerging technologies and the major changes they are bringing with them. If nothing else, the panel might have wanted to make mention of artificial intelligence how the increasing role of automated systems may be affecting science culture in Canada. For example, in my July 16, 2014 post I described a deal Associated Press (AP) signed with a company that automates the process of writing sports and business stories. You may well have read a business story (AP contracted for business stories) written by an artificial intelligence system or, if you prefer the term, an algorithm.

The recommendation for ‘Enhancing science communication and engagement’ is where I believe the Expert Panel should be offered a bouquet,

… Given the significance of government science in many areas of research, government science communication constitutes an important vector for increasing public awareness and understanding about science. In Canada current policies governing how scientists working in federal departments and agencies are allowed to interact with the media and the public have come under heavy criticism in recent years …

Concerns about the federal government’s current policies on government scientists’ communication with the media have been widely reported in Canadian and international
press in recent years (e.g., Ghosh, 2012; CBC, 2013c; Gatehouse, 2013; Hume, 2013; Mancini, 2013; Munro, 2013). These concerns were also recently voiced by the editorial board of Nature (2012), which unfavourably compared Canada’s current approach with the more open policies now in place in the United States. Scientists at many U.S. federal agencies are free to speak to the media without prior departmental approval, and to
express their personal views as long as they clearly state that they are not speaking on behalf of the government. In response to such concerns, and to a formal complaint filed by the Environmental Law Clinic at the University of Victoria and Democracy Watch, on April 2, 2013 Canada’s Information Commissioner launched an investigation into whether current policies and policy instruments in seven federal departments and agencies are “restricting or prohibiting government scientists from speaking with or sharing research with the media and the Canadian public” (OICC, 2013).

Since these concerns have come to light, many current and former government scientists have discussed how these policies have affected their interactions with the media. Marley Waiser, a former scientist with Environment Canada, has spoken about how that department’s policies prevented her from discussing her research on chemical pollutants in Wascana Creek near Regina (CBC, 2013c). Dr. Kristi Miller, a geneticist with the Department of Fisheries and Oceans, was reportedly prevented from speaking publicly about a study she published in Science, which investigated whether a viral infection might be the cause of declines in Sockeye salmon stocks in the Fraser River (Munro, 2011).

According to data from Statistics Canada (2012), nearly 20,000 science and technology professionals work for the federal government. The ability of these researchers to communicate with the media and the Canadian public has a clear bearing on Canada’s science culture. Properly supported, government scientists can serve as a useful conduit for informing the public about their scientific work, and engaging the public in discussions about the social relevance of their research; however, the concerns reported above raise questions about the extent to which current federal policies in Canada are limiting these opportunities for public communication and engagement. (pp. 190/1 PDF; p. 158/9 print)

Kudos for including the information and for this passage as well,

Many organizations including science centres and museums, research centres, and even governments may be perceived as having a science promotion agenda that portrays only the benefits of science. As a result, these organizations are not always seen as promoters of debate through questioning, which is a crucial part of the scientific process. Acknowledging complexity and controversy is another means to improve the quality of public engagement in science in a range of different contexts. (p. 195 PDF; p. 163 print)

One last happy note, which is about integrating the arts and design into the STEM (science, technology, engineering, and mathematics communities),

Linking Science to the Arts and Design U.S. advocates for “STEM to STEAM” call for an incorporation of the arts in discussions of science, technology, engineering, and mathematics in an effort to “achieve a synergistic balance” (Piro, 2010). They cite positive outcomes such as cognitive development, reasoning skills, and concentration abilities. Piro (2010) argues that “if creativity, collaboration, communication, and critical thinking — all touted as hallmark skills for 21st-century success — are to be cultivated, we need to ensure that STEM subjects are drawn closer to the arts.” Such approaches offer new techniques to engage both student and adult audiences in science learning and engagement opportunities.

What I find fascinating about this STEM to STEAM movement is that many of these folks don’t seem to realize is that until fairly recently the arts and sciences recently have always been closely allied.  James Clerk Maxwell was also a poet, not uncommon amongst 19th century scientists.

In Canada one example of this approach is found in the work of Michael R. Hayden, who has conducted extensive genetic research on Huntington disease. In the lead-up to the 2000 Human Genome Project World Conference, Hayden commissioned Vancouver’s Electric Company Theatre to fuse “the spheres of science and art in a play that explored the implications of the revolutionary technology of the Human Genome Project” (ECT, n.d.). This play, The Score, was later adapted into a film. Hayden believes that his play “transforms the scientific ideas explored in the world of the laboratory into universal themes of human identity, freedom and creativity, and opens up a door for a discussion between the scientific community and the public in general” (Genome Canada, 2006). (p. 196 PDF; p. 164 print)

I’m not sure why the last recommendation presents an either/or choice, ‘Providing national or regional leadership’, while the following content suggests a much more fluid state,

…  it should be recognized that establishing a national or regional vision for science culture is not solely the prerogative of government. Such a vision requires broad support and participation from the community of affected stakeholders to be effective, and can also emerge from that community in the absence of a strong governmental role.

The final chapter (the seventh) restates the points the panel has made throughout its report. Unexpectedly, part 2 got bigger, ’nuff said.

* Removed word from this sentence: “For example, in my July 16, 2014 post I [made removed] described a deal Associated Press (AP) signed with a company that automates the process of writing sports and business stories.” on Nov. 17, 2020.

Part 2 (a) of 3: Science Culture: Where Canada Stands; an expert assessment (reconstructed)

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Losing over 2000 words, i.e., part 2 of this commentary on the Science Culture: Where Canada Stands assessment by the Council of Canadian Academies (CAC) on New Year’s Eve 2014 was a bit of blow. So, here’s my attempt at reconstructing my much mourned part 2.

There was acknowledgement of Canada as an Arctic country and an acknowledgement of this country’s an extraordinary geographical relationship to the world’s marine environment,

Canada’s status as an Arctic nation also has a bearing on science and science culture. Canada’s large and ecologically diverse Arctic landscape spans a substantial part of the circumpolar Arctic, and comprises almost 40% of the country’s landmass (Statistics Canada, 2009). This has influenced the development of Canadian culture more broadly, and also created opportunities in the advancement of Arctic science. Canada’s northern inhabitants, the majority of whom are Indigenous peoples, represent a source of knowledge that contributes to scientific research in the North (CCA, 2008).

These characteristics have contributed to the exploration of many scientific questions including those related to environmental science, resource development, and the health and well-being of northern populations. Canada also has the longest coastline of any country, and these extensive coastlines and marine areas give rise to unique research opportunities in ocean science (CCA, 2013a). (p. 55 PDF; p. 23 print)

Canada’s aging population is acknowledged in a backhand way,

Like most developed countries, Canada’s population is also aging. In 2011 the median age in Canada was 39.9 years, up from 26.2 years in 1971 (Statistics Canada, n.d.). This ongoing demographic transition will have an impact on science culture in Canada in years to come. An aging population will be increasingly interested in health and medical issues. The ability to make use of this kind of information will depend in large part on the combination of access to the internet, skill in navigating it, and a conceptual toolbox that includes an understanding of genes, probability, and related constructs (Miller, 2010b). (p. 56 PDF; p. 24 print)

Yes, the only science topics of interest for an old person are health and medicine. Couldn’t they have included one sentence suggesting an aging population’s other interests and other possible impacts on science culture?

On the plus side, the report offers a list of selected Canadian science culture milestones,

• 1882 – Royal Society of Canada is established.
• 1916 – National Research Council is established.
• 1923 – Association canadienne-française pour l’avancement des sciences (ACFAS) is established.
• 1930 – Canadian Geographic is first published by the Royal Canadian Geographical Society.
• 1951 – Massey–Lévesque Commission calls for the creation of a national science and technology museum.
• 1959 – Canada sees its first science fairs in Winnipeg, Edmonton, Hamilton, Toronto, Montréal, and Vancouver; volunteer coordination eventually grows into Youth Science Canada.
• 1960 – CBC’s Nature of Things debuts on television; Fernand Séguin hosts “Aux frontières de la science.”
• 1962 – ACFAS creates Le Jeune scientifique, which becomes Québec Science in 1970.
• 1966 – Science Council of Canada is created to advise Parliament on science and technology issues.
• 1967 – Canada Museum of Science and Technology is created.
• 1969 – Ontario Science Centre opens its doors (the Exploratorium in San Francisco opens the same year).
• 1971 – Canadian Science Writers’ Association is formed.
• 1975 – Symons Royal Commission on Canadian Studies speaks to how understanding the role of science in society is important to understanding Canadian culture and identity.
• 1975 – Quirks and Quarks debuts on CBC Radio.
• 1976 – OWL children’s magazine begins publication.
• 1977 – Association des communicateurs scientifiques du Québec is established.
• 1978 – L’Agence Science-Presse is created.
• 1981 – Association des communicateurs scientifiques creates the Fernand-Séguin scholarship to identify promising young science journalists.
• 1982 – Les Débrouillards is launched in Quebec. (p. 58 PDF; p. 26 print)

The list spills onto the next page and into the 2000’s.

It’s a relief to see the Expert Panel give a measured response to the claims made about science culture and its various impacts, especially on the economy (in my book, some of the claims have bordered on hysteria),

The Panel found little definitive empirical evidence of causal relationships between the dimensions of science culture and higher-level social objectives like stronger economic performance or more effective public policies. As is the case with much social science research, isolating the impacts of a single variable on complex social phenomena is methodologically challenging, and few studies have attempted to establish such relationships in any detail. As noted in 1985 by the Bodmer report (a still-influential report on public understanding of science in the United Kingdom), although there is good reason prima facie to believe that improving public understanding of science has national economic benefits, empirical proof for such a link is often elusive (RS & Bodmer, 1985). This remains the case today. Nevertheless, many pieces of evidence suggest why a modern, industrialized society should cultivate a strong science culture. Literature from the domains of cognitive science, sociology, cultural studies, economics, innovation, political science, and public policy provides relevant insights. (p. 63 PDF; p. 31 print)

Intriguingly, while the panel has made extensive use of social science methods for this assessment there are some assumptions made about skill sets required for the future,

Technological innovation depends on the presence of science and technology skills in the workforce. While at one point it may have been possible for relatively low-skilled individuals to substantively contribute to technological development, in the 21st century this is no longer the case. [emphasis mine] Advanced science and technology skills are now a prerequisite for most types of technological innovation. (p. 72 PDF; p. 40 print)

Really, it’s no longer possible for relatively low-skilled individuals to contribute to technological development? Maybe the expert panel missed this bit in my March 27, 2013 post,

Getting back to Bittel’s Slate article, he mentions Foldit (here’s my first piece in an Aug. 6, 2010 posting [scroll down about 1/2 way]), a protein-folding game which has generated some very exciting science. He also notes some of that science was generated by older, ‘uneducated’ women. Bittel linked to Jeff Howe’s Feb. 27, 2012 article about Foldit and other crowdsourced science projects for Slate where I found this very intriguing bit,

“You’d think a Ph.D. in biochemistry would be very good at designing protein molecules,” says Zoran Popović, the University of Washington game designer behind Foldit. Not so. “Biochemists are good at other things. But Foldit requires a narrow, deeper expertise.”

Or as it turns out, more than one. Some gamers have a preternatural ability to recognize patterns, an innate form of spatial reasoning most of us lack. Others—often “grandmothers without a high school education,” says Popovic—exercise a particular social skill. “They’re good at getting people unstuck. They get them to approach the problem differently.” What big pharmaceutical company would have anticipated the need to hire uneducated grandmothers? (I know a few, if Eli Lilly HR is thinking of rejiggering its recruitment strategy.) [emphases mine]

It’s not the idea that technical and scientific skills are needed that concerns me; it’s the report’s hard line about ‘low skills’ (which is a term that is not defined). In addition to the notion that future jobs require only individuals with ‘high level’ skills; there’s the notion (not mentioned in this report but gaining general acceptance in the media) that we shouldn’t ever have to perform repetitive and boring activities. It’s a notion which completely ignores a certain aspect of the learning process. Very young children repeat over and over and over and over … . Apprenticeships in many skills-based crafts were designed with years of boring, repetitive work as part of the training. It seems counter-intuitive but boring, repetitive activities can lead to very high level skills such as the ability to ‘unstick’ a problem for an expert with a PhD in biochemistry.

Back to the assessment, the panel commissioned a survey, conducted in 2013, to gather data about science culture in Canada,

The Panel’s survey of Canadian science culture, designed to be comparable to surveys undertaken in other countries as well as to the 1989 Canadian survey, assessed public attitudes towards science and technology, levels and modes of public engagement in science, and public science knowledge or understanding. (The evidence reported in this chapter on the fourth dimension, science and technology skills, is drawn from other sources such as Statistics Canada and the OECD).

Conducted in April 2013, the survey relied on a combination of landline and mobile phone respondents (60%) and internet respondents (40%), randomly recruited from the general population. In analyzing the results, responses to the survey were weighted based on Statistics Canada data according to region, age, education, and gender to ensure that the sample was representative of the Canadian public. 7 A total of 2,004 survey responses were received, with regional breakdowns presented in Table 4.1. At a national level, survey results are accurate within a range of plus or minus 2.2% 19 times out of 20 (i.e., at the 95% confidence interval), and margins of error for regional results range from 3.8% to 7.1%). Three open-ended questions were also included in the survey, which were coded using protocols previously applied to these questions in other international surveys. 8 All open-ended questions were coded independently by at least three bilingual coders, and any discrepancies in coding were settled through a review by a fourth coder. (p. 79 PDF; p. 47 print)

The infographic’s data in part 1 of this commentary, What Do Canadians Think About Science and Technology (S&T)? is based on the survey and other statistical information included in the report especially Chapter four focused on measurements (pp. 77  – 127 PDF; pp. 45 – 95 print). While the survey presents a somewhat rosier picture of the Canadian science culture than the one I experience on a daily basis, the data seems to have been gathered in a thoughtful fashion. Regardless of the assessment’s findings and my opinions,  how Canadians view science became a matter of passionate debate in the Canadian science blogging community (at least parts of it) in late 2014 as per a Dec. 3, 2014 posting by the Science Borealis team on their eponymous blog (Note: Links have been removed),

The CBC’s Rick Mercer is a staunch science advocate, and his November 19th rant was no exception. He addressed the state of basic science in Canada, saying that Canadians are “passionate and curious about science.”

In response, scientist David Kent wrote a post on the Black Hole Blog in which he disagreed with Mercer, saying, “I do not believe Mr. Mercer’s idea that Canadians as a whole are interested although I, like him, would wish it to be the case.”

Kent’s post has generated some fierce discussion, both in the comments on his original post and in the comments on a Facebook post by Evidence for Democracy.

Here at Science Borealis, we rely on a keen and enthusiastic public to engage with the broad range of science-based work our bloggers share, so we decided to address some of the arguments Kent presented in his post.

Anecdotal evidence versus data

Kent says “Mr. Mercer’s claims about Canadians’ passions are anecdotal at best, and lack any evidence – indeed it is possible that Canadians don’t give a hoot about science for science’s sake.”

Unfortunately, Kent’s own argument is based on anecdotal evidence (“To me it appears that… the average Canadian adult does not particularly care about how or why something works.”).

If you’re looking for data, they’re available in a recent Council of Canadian Academies report that specifically studied science culture in Canada. Results show that Canadians are very interested in science.

…

You can find David Kent’s Nov. 26, 2014 post about Canadians, Rick Mercer and science here. Do take a look at the blog’s comments which feature a number of people deeply involved in promoting and producing Canadian science culture.

I promised disturbing statistics in the head for this posting and here they are in the second paragraph,

Canadian students perform well in PISA [Organization for Economic Cooperation and Development’s (OECD) Programme for International Student Assessment (PISA)] , with relatively high scores on all three of the major components of the assessment (reading, science, and mathematics) compared with students in other countries (Table 4.4). In 2012 only seven countries or regions had mean scores on the science assessment higher than Canada on a statistically significant basis: Shanghai–China, Hong Kong–China, Singapore, Japan, Finland, Estonia, and Korea (Brochu et al., 2013). A similar pattern holds for mathematics scores, where nine countries had mean scores higher than Canada on a statistically significant basis: Shanghai–China, Singapore, Hong Kong–China, Chinese Taipei, Korea, Macao–China, Japan, Lichtenstein, and Switzerland (Brochu et al., 2013). Regions scoring higher than Canada are concentrated in East Asia, and tend to be densely populated, urban areas. Among G8 countries, Canada ranks second on mean science and mathematics scores, behind Japan.

However, the 2012 PISA results also show statistically significant declines in Canada’s scores on both the mathematics and science components. Canada’s science score declined by nine points from its peak in 2006 (with a fall in ranking from 3rd to 10th), and the math score declined by 14 points since first assessed in 2003 (a fall from 7th to 13th) (Brochu et al., 2013). Changes in Canada’s standing relative to other countries reflect both the addition of new countries or regions over time (i.e., the addition of regions such as Hong Kong–China and Chinese Taipei in 2006, and of Shanghai–China in 2009) and statistically significant declines in mean scores.

My Oct. 9, 2013 post discusses the scores in more detail and as the Expert Panel notes, the drop is disconcerting and disturbing. Hopefully, it doesn’t indicate a trend.

Part 2 (b) follows immediately.

*Word corrected in this sentence: “There was acknowledgement of Canada as [a changed to an] Arctic country and an acknowledgement of this country’s an extraordinary geographical relationship to the world’s marine environment.” on Nov. 17, 2020

OECD’s (Organization for Economic Cooperation and Development) latest report on its regulating manufactured nanomaterials questionnaire

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As I have commented on several occasions, most of my information about Canada’s activities with regard to risk and nanomaterials comes from outside the country, notably the OECD (Organization for Economic Cooperation and Development).

Thanks* to Lynn Bergeson and her Sept. 17, 2014 posting on Nanotechnology Now for information about the latest publication from the OECD’s Working Party on Manufactured Nanomaterials (Note: a link has been removed),

On September 16, 2014, the Organization for Economic Cooperation and Development (OECD) published a document entitled Report of the Questionnaire on Regulatory Regimes for Manufactured Nanomaterials 2010-2011. … The Report summarizes responses to the Working Party on Manufactured Nanomaterials (WPMN) Questionnaire on Regulated Nanomaterials: 2010-2011, which was issued July 12, 2012. The Questionnaire contained four sections related to the oversight of nanomaterials in various OECD jurisdictions: regulatory updates; definitions and/or legal approaches for nanomaterials by jurisdiction; regulatory challenges; and opportunities for collaboration.

You can find all of the reports from the OECD’s WPMN here, including this latest report, which is no. 42, Report of the questionnaire on regulatory regimes for manufactured nanomaterials 2010-201, ENV/JM/MONO(2014)28. This is the third time there’s been a questionnaire and subsequent report.

I have quickly skimmed through the report and found a few interesting items about Canada’s current activities and collaborations vis à vis manufactured nanomaterials and risk. From the REPORT OF THE QUESTIONNAIRE ON REGULATORY REGIMES FOR MANUFACTURED NANOMATERIALS 2010-2011 which appears to have been published Sept. 4, 2014. I have had an unusually difficult time including excerpts from the report along with page numbers, etc. On the first try, after almost an hour of cutting and pasting, I was unable to get an intelligible version into a preview. To all intents and purposes the text was in place but the preview attempt resulted in a bizarre column of text overwriting the sidebar to the right of the posts.

I tried again and found that extensive reformatting was necessary and that the original table format has been lost. Nonetheless. you will find there are two pieces of legislation being reported on, CEPA (1999), which I believe has something to do with Environment Canada, and F&DA, which seems to be associated with Health Canada. One or both pieces of legislation may be referenced as per the OECD report. Page numbers from the document are included after the excerpted table entries.

Table 12: Hazard identification …

CEPA (1999)

Extrapolation between nanomaterials (i.e., choosing the appropriate surrogate)

Validity of testing methods and analytical tools to detect, characterize and measure nanomaterials

Participating in international forums such as the WPMN [OECD Working Party on Manufactured Nanomaterials], Expert Meetings, and ISO [International Standards Organization] TC/229 to support the generation and synthesis of appropriate science.

Support domestic research to help minimize challenges in hazard identification.

F&DA

Nanomaterial-based products under the F&DA (i.e. nanomedicines) can be associated with a broad spectrum of toxicities that are dependent on the nanoparticle properties (e.g. size, surface charge and solubility). However, there is currently no specific guidance document available for nanomedicines. Nanoparticle properties can significantly impact the PK profile/biodistribution of nanomedicines resulting in safety concerns. The components of the nanomedicines can also interact with the immune system and may trigger unique immunogenicity/immunotoxicity profile. Animals are generally not predictive of immunological responses for biologics (however, it may not be the case if the nanomedicine is a chemical drug), it is likely that immunological studies for nanomedicines should be carried out in human clinical trials. Long term studies may be required for a nanomaterial that persist and accumulated in particular tissues for an extended period of time.  p. 45

Table 13: Health and safety …

F&DA Veterinary Drugs

Due to the lack of a comprehensive understanding of the effects of nanomaterials on human, animal and environmental health, the Veterinary Drugs Directorate has not yet established a comprehensive occupational health and safety policy. Moreover, occupational health and safety is a shared responsibility between the federal and provincial governments in Canada.

At this time, there is no conclusive evidence linking exposure of nanomaterials from veterinary drugs or food sources to negative impact on human health. Additional research is necessary before a definitive policy approach can be taken.

F&DA Veterinary Drugs
Veterinary drugs including those that contain nanomaterials are regulated by the Food and Drugs Act and the Food and Drug Regulations. These provide the Veterinary Drugs Directorate with the authority to regulate the human health and safety aspects of veterinary drug products. The Regulations cover the aspects of the manufacturing, human and animal safety and efficacy assessment, and post-market surveillance of veterinary drug products including those containing nanomaterials. The latter products are subject to the same rigorous assessments as non-nanomaterial-containing veterinary drug products. p. 47

Table 14: Risk Assessment Methodologies

CEPA (1999)

Our understanding of risk assessments of nanomaterials is still evolving. Nanomaterials regulated under the industrial chemicals program employ a precautionary approach (i.e., exposure is typically mitigated), and nano-relevant information is requested whenever appropriate to conduct more informed risk assessments.

Canada also continues to work in international projects, such as the international life sciences institute NanoRelease project aimed at developing methods to quantify releases of nanomaterials from solid matrices.

Canada is also part of the Regulatory Cooperation Council (RCC) Nanotechnology Initiative with the United States. Under this project, Canada and the US are developing a classification scheme for nanomaterials to inform on the utilization of analogue/read- across, developing frameworks and common assumptions to better
inform risk assessments, and mining public and confidential use information to increase marketplace knowledge of nanomaterials. p. 49

Table 15: Risk Management and Nanomaterials in Commerce …

CEPA (1999)

Knowledge of use profiles of industrial nanomaterials; lack of specificity in risk
management measures given the overall lack of information and nomenclature systems for nanomaterials

Under the RCC, Canada and the US are gathering information on the uses of industrial nanomaterials in the two countries.  p. 52

Table 16: Research … (to support regulatory decisions)

CEPA (1999)

– foster domestic and international capacity to generate research on risk assessment priorities and needs
– applying research findings to nanomaterial risk assessments
– using research on nanomaterials to extrapolate to other nanomaterials

– Canada is actively supporting domestic and international research projects to help inform risk assessments.

F&DA

Filling knowledge gaps

HC [Health Canada] is conducting laboratory research to study the effects of lipid nanoparticles on the thermal stability of various recombinant proteins with the aim of identifying determinants of susceptibility to unintended deleterious interactions.  p. 55

Table 17: Impact of Regulatory Actions and Innovations and Economic Growth

CEPA (1999)

How to obtain the necessary information on nanomaterials, and how to regulate them in a manner that does not prevent them from offering their many benefits to society.

Consult with industry on proposed approaches. Focus information requests and requirements.  pp. 56/7

Table 18: Labelling Communication of Nanomaterials …

CEPA (1999)

Labelling of nanomaterials has not been considered under CEPA 1999 to date. p. 58

Table 19: Collaboration with other countries …

CEPA (1999) & F&DA

New Substances Program is involved in various international activities, including:
1) International Organization for Standardization (ISO) Technical Committee (TC) 229 on Nanotechnologies
2) Organisation for Economic Co-operation and Development (OECD) Working Party on
Manufactured Nanomaterials (WPMN) and Working Party on Nanotechnology (WPN)
3) Canada-US Regulatory Cooperation Council (RCC)
4) International Cooperation on Cosmetic Regulation (ICCR) – 2 Reports have been published
a) Criteria and Methods of Detection for Nanomaterials in Cosmetics:
http://www.fda.gov/downloads/InternationalPrograms/HarmonizationInitiatives/UCM235485.pdf
b) Methods for Characterization of Nanomaterials in Cosmetics
http://ec.europa.eu/consumers/sectors/cosmetics/files/pdf/iccr5_char_nano_en.pdf
5) International Regulators Nanotechnology Working Group
6) International Life Sciences Institutes (ILSI) – NanoRelease Food Additive Project
7) NanoLyse

In addition, for veterinary drugs, Health Canada collaborates with other regulatory agencies in USA, Europe, Australia, etc in the regulation of non-nanomaterial products and substances and would do the same for substances that are, or products containing nanomaterials pp. 59/60

Table 19: Expert Workshop Sponsorship [table number repetition noted]

CEPA (1999)

The Workshop on the Human and Environmental Risk Assessment of Nanomaterials convened by Health Canada and Environment Canada (March 24-26, 2010) provided an open forum for detailed dialogue on nanomaterials among science evaluators, research scientists and regulators. The Workshop was attended by 25 experts from Australia, Canada, Europe, Korea and the United States of America. In addition, seven observers attended the Workshop.

Regulatory Cooperation Council with the United States

F&DA Foods

Health Canada will be hosting a Joint NanoLyse/NanoRelease Workshop to discuss methods and safety of nanomaterials and share information from the respective projects. NanoLyse is an EU research consortium to develop methods of analysis for engineered nano-materials in foods and NanoRelease is an International Life Sciences Institute lead initiative to develop of analytical methods, alimentary canal models for uptake of engineered nano-materials and review of regulatory issues. p. 61

In any event, good luck with the reading and you can find out more about NanoLyse here and more about Canadian participation in the NanoRelease Food Additive Steering Committee project here.

* ‘Thank’s’ changed to ‘Thanks’ on April 7, 2015

Corporate influence, nanotechnology regulation, and Friends of the Earth (FoE) Australia

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The latest issue of the newsletter, Chain Reaction # 121, July 2014, published by Friends of the Earth (FoE) Australia features an article by Louise Sales ‘Corporate influence over nanotechnology regulation‘ that has given me pause. From the Sales article,

I recently attended an Organisation for Economic Co-operation and Development (OECD) seminar on the risk assessment and risk management of nanomaterials. This was an eye-opening experience that graphically illustrated the extent of corporate influence over nanotechnology regulation globally. Representatives of the chemical companies DuPont and Evonik; the Nanotechnology Industries Association; and the Business and Industry Advisory Committee to the OECD (BIAC) sat alongside representatives of countries such as Australia, the US and Canada and were given equal speaking time.

BIAC gave a presentation on their work with the Canadian and United States Governments to harmonise nanotechnology regulation between the two countries. [US-Canada Regulatory Cooperative Council] [emphasis mine] Repeated reference to the involvement of ‘stakeholders’ prompted me to ask if any NGOs [nongovernmental organizations] were involved in the process. Only in the earlier stages apparently − ‘stakeholders’ basically meant industry.

A representative of the Nanotechnology Industries Association told us about the European NANoREG project they are leading in collaboration with regulators, industry and scientists. This is intended to ‘develop … new testing strategies adapted to innovation requirements’ and to ‘establish a close collaboration among authorities, industry and science leading to efficient and practically applicable risk management approaches’. In other words industry will be helping write the rules.

Interestingly, when I raised concerns about this profound intertwining of government and industry with one of the other NGO representatives they seemed almost dismissive of my concerns. I got the impression that most of the parties concerned thought that this was just the ‘way things were’. As under-resourced regulators struggle with the regulatory challenges posed by nanotechnology − the offer of industry assistance is probably very appealing. And from the rhetoric at the meeting one could be forgiven for thinking that their objectives are very similar − to ensure that their products are safe. Right? Wrong.

I just published an update about the US-Canada Regulatory Cooperation Council (RCC; in  my July 14, 2014 posting) where I noted the RCC has completed its work and final reports are due later this summer. Nowhere in any of the notices is there mention of BIAC’s contribution (whatever it might have been) to this endeavour.

Interestingly. BIAC is not an OECD committee but a separate organization as per its About us page,

BIAC is an independent international business association devoted to advising government policymakers at OECD and related fora on the many diversified issues of globalisation and the world economy.

Officially recognised since its founding in 1962 as being representative of the OECD business community, BIAC promotes the interests of business by engaging, understanding and advising policy makers on a broad range of issues with the overarching objectives of:

  • Positively influencing the direction of OECD policy initiatives;

  • Ensuring business and industry needs are adequately addressed in OECD policy decision instruments (policy advocacy), which influence national legislation;

  • Providing members with timely information on OECD policies and their implications for business and industry.

Through its 38 policy groups, which cover the major aspects of OECD work most relevant to business, BIAC members participate in meetings, global forums and consultations with OECD leadership, government delegates, committees and working groups.

I don’t see any mention of safety either in the excerpt or elsewhere on their About us page.

As Sales notes in her article,

Ultimately corporations have one primary driver and that’s increasing their bottom line.

I do wonder why there doesn’t seem to have been any transparency regarding BIAC’s involvement with the RCC and why no NGOs (according to Sales) were included as stakeholders.

While I sometimes find FoE and its fellow civil society groups a bit shrill and over-vehement at times, It never does to get too complacent. For example, who would have thought that General Motors would ignore safety issues (there were car crashes and fatalities as a consequence) over the apparently miniscule cost of changing an ignition switch. From What is the timeline of the GM recall scandal? on Vox.com,

…

March 2005: A GM project engineering manager closed the investigation into the faulty switches, noting that they were too costly to fix. In his words: “lead time for all solutions is too long” and “the tooling cost and piece price are too high.” Later emails unearthed by Reuters suggested that the fix would have cost GM 90 cents per car. [emphasis mine]

…

March 2007: Safety regulators inform GM of the death of Amber Rose, who crashed her Chevrolet Cobalt in 2005 after the ignition switch shut down the car’s electrical system and air bags failed to deploy. Neither the company nor regulators open an investigation.

…

End of 2013: GM determines that the faulty ignition switch is to blame for at least 31 crashes and 13 deaths.

…

According to a July 17, 2014 news item on CBC (Canadian Broadcasting Corporation) news online, Mary Barra, CEO of General Motors, has testified on the mater before the US Senate for a 2nd time, this year,

A U.S. Senate panel posed questions to a new set of key players Thursday [July 17, 2014] as it delves deeper into General Motors’ delayed recall of millions of small cars.

…

An internal report found GM attorneys signed settlements with the families of crash victims but didn’t tell engineers or top executives about mounting problems with ignition switches. It also found that GM’s legal staff acted without urgency.

GM says faulty ignition switches were responsible for at least 13 deaths. It took the company 11 years to recall the cars.

…

Barra will certainly be asked about how she’s changing a corporate culture that allowed a defect with ignition switches to remain hidden from the car-buying public for 11 years. It will be Barra’s second time testifying before the panel.

H/T ICON (International Council on Nanotechnology) July 16, 2014 news item. Following on the topic of transparency, ICON based at Rice University in Texas (US) has a Sponsors webpage.

Deadline extension (travel grants and poster abstracts) for alternate testing strategies (ATS) of nanomaterials workshop

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It seems there have been a couple of deadline extensions (to August 1, 2014) for the September 15-16, 2014 ‘Workshop to Explore How a Multiple Models Approach can Advance Risk Analysis of Nanoscale Materials’ in Washington, DC (first mentioned in my July 10, 2014 posting featuring a description of the workshop). You can go here to submit a poster abstract (from any country) and you can go here if you’re a student or young professional (from any country) in search of a $500 travel award.

I managed to speak to one of the organizers, Lorraine Sheremeta, (Assistant Director, Ingenuity Lab, University of Alberta and co-author a July 9, 2014 Nanowerk Spotlight article about the workshop). Lorraine (Lori) kindly spoke to me about the upcoming workshop, which she described as an academic conference,.

As I understand what she told me, the hosts for the September 15-16, 2014 Workshop to Explore How a Multiple Models Approach can Advance Risk Analysis of Nanoscale Materials in Washington, DC want to attract a multidisciplinary group of people to grapple with a few questions. First, they want to establish a framework for establishing which are the best test methods for nanomaterials. Second, they are trying to move away from animal testing and want to establish which methods are equal to or better than animal testing. Thirdly, they want to discuss what they are going to do with the toxicological data  that we have  been collecting on nanomaterials for years now.

Or, as she and her colleague from the Society of Risk Analysis (Jo Anne Shatkin) have put in it in their Nanowerk Spotlight article:

… develop a report on the State of the Science for ATS for nanomaterials, catalogue of existing and emerging ATS [alternate testing strategies] methods in a database; and develop a case study to inform workshop deliberations and expert recommendations

The collaborative team behind this event includes, the University of Alberta’s Ingenuity Lab, the Society for Risk Analysis, Environment Canada, Health Canada, and the Organization for Economic Co-operation and Development (OECD) Working Party on Manufactured Nanomaterials (WPMN) .

The speaker lineup isn’t settled at this time although they have confirmed Vicki Stone of Heriot-Watt University in Scotland (from her university bio page),

Vicki Stone, Professor of Toxicology, studies the effects of nanomaterials on humans and environmentally relevant species.  Current research projects investigate the mechanism of toxicity of a range of nanomaterials in cells of the immune system (macrophages and neutrophils), liver (hepatocytes) , gastrointestinal tract, blood vessels (endothelium) and lung.  She is interested in interactions between nanomaterials, proteins and lipids, and how this influences subsequent toxicity.  Current projects also develop in vitro alternatives using microfluidics as well as high resolution imaging of individual nanomaterials in 3D and over time.  In addition Vicki collaborates with ecotoxicologists to investigate the impacts of nanomaterials on aquatic organisms. Vicki coordinated a European project to identify the research priorities to develop an intelligent testing strategy for nanomaterials (www.its-nano.eu).

Vicki is Director of the Nano Safety Research Group at Heriot-Watt University, Edinburgh, and Director of Toxicology for SAFENANO (www.safenano.org). She has acted as the Editor-in-chief of the journal Nanotoxicology (http://informahealthcare.com/nan) for 6 years (2006-2011). Vicki has also published over 130 publications pertaining to particle toxicology over the last 16 years and has provided evidence for the government commissioned reports published by the Royal Society (2003) and the on Environmental Pollution (2008).  Vicki was previously a member of the UK Government Committee on the Medical Effects of Air Pollution (COMEAP) and an advisory board member for the Center for the Environmental Implications of NanoTechnology (CEINT; funded by the US Environmental Protection Agency)).

A representative from PETA (People for the Ethical Treatment of Animals) will also be speaking. I believe that will be Amy Clippinger (from the PETA website’s Regulatory Testing webpage; scroll down about 70% of the way),

Science adviser Amy Clippinger has a Ph.D. in cellular and molecular biology and genetics and several years of research experience at the University of Pennsylvania.

PETA representatives have been to at least one other conference on the topic of nano, toxicology, and animal testing as per my April 24, 2014 posting about NANOTOX 2014 in Turkey,

Writing about nanotechnology can lead you in many different directions such as the news about PETA (People for the Ethical Treatment of Animals) and its poster presentation at the NanoTox 2014 conference being held in Antalya, Turkey from April 23 – 26, 2014. From the April 22, 2014 PETA news release on EurekAlert,

PETA International Science Consortium Ltd.’s nanotechnology expert will present a poster titled “A tiered-testing strategy for nanomaterial hazard assessment” at the 7th International Nanotoxicology Congress [NanoTox 2014] to be held April 23-26, 2014, in Antalya, Turkey.

Dr. Monita Sharma will outline a strategy consistent with the 2007 report from the US National Academy of Sciences, “Toxicity Testing in the 21st Century: A Vision and a Strategy,” which recommends use of non-animal methods involving human cells and cell lines for mechanistic pathway–based toxicity studies.

There is a lot of interest internationally in improving how we test for toxicity of nanomaterials. As well, the drive to eliminate or minimize as much as possible the use of animals in testing seems to be gaining momentum.

Good luck to everyone submitting a poster abstract and/or an application for a travel grant!

In case you don’t want to scroll up, the SRA nano workshop website is here.

Canada-US joint Regulatory Cooperation Council nanotechnology initiative completed and Canada endorses OECD nanomaterials recommendation

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Thanks to Lynn Bergeson’s July 9, 2014 posting on Nanotechnology Now, I learned the Canada-US joint Regulatory Cooperation Council (RCC) nanotechnology initiative has completed its work and will be filing final reports later this summer (2014).

I have featured the RCC here in at least three postings, a Dec. 3, 2012 posting, a June 26, 2013 posting, and a January 21, 2014 posting. Briefly, the RCC was first announced in 2011 and is intended to harmonize Canadian and US regulatory frameworks in a number of areas including, agriculture and food, transportation, personal care products and pharmaceuticals and more. Significantly, nanotechnology was also part of their portfolio.

The latest information about RCC doings was obtained from the Canadian government’s 2014 summer issue of the Chemicals Management Plan (CMP) Progress Report (a second thank you for Bergeson for information about this publication),

The Canada-U.S. Regulatory Cooperation Council Nanotechnology Initiative is now complete. Canada and the U.S. are implementing the new approaches and lessons learned in risk assessments of nanomaterials. An important outcome of the initiative is the development of consistent policy principles on the regulatory oversight of nanomaterials, which have now been endorsed by the Government of Canada. Watch for the publication of the final reports from the Canada-U.S. Regulatory Cooperation Council Nanotechnology Initiative this summer. The reports will include recommendations about ways in which Canada and the U.S. can align their nanomaterial regulatory work, including the application of consistent risk assessment approaches and methodologies and identifying categories of nanomaterials.

The 2014 CMP summer issue offers a second tidbit of information. This time it’s about Canada and the OECD,

Canada has endorsed a recommendation from the Organisation for Economic Co-operation and Development’s Council on the Safety Testing and Assessment of Manufactured Nanomaterials. The recommendation states that countries “apply the existing international and national chemical regulatory frameworks or other management systems, adapted to take into account the specific properties of manufactured nanomaterials.” The recommendation was based on the work of the Organisation for Economic Co-operation and Development’s Working Party on Manufactured Nanomaterials, which is a harmonization effort to inform regulatory programs regarding the environmental and health and safety implications of manufactured nanomaterials.

For enthusiasts, Canada’s Chemicals Management Plan progress report is expected to be published twice/year. There are now two issues available, the first with a Dec. 30, 2013 publication date. Here’s more about the CMP progress reports,

The Chemicals Management Plan Progress Report has been created to keep stakeholders and other interested parties up to date on the activities and programs related to Canada’s Chemicals Management Plan (CMP). The report is produced jointly by Environment Canada and Health Canada and will be published twice a year. It will report on advances in major initiatives and highlight key activities related to the Government of Canada’s recent work under the CMP. It will also inform you about coming events, dates of interest and how to get involved.

We encourage you to share the reports with anyone who may be interested. We also welcome your feedback or suggestions. We can be reached at Substances@ec.gc.ca.

Anyone interested in more information about the RCC (Regulatory Cooperation Council) and its nanotechnology efforts can find it here.

An upcoming alternate testing strategies (ATS) for nanomaterials workshop and the quest to reduce animal testing

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It’s too late to announce a call for poster abstracts or travel awards but that still leaves the possibility of attending a September 15-16, 2014 Workshop to Explore How a Multiple Models Approach can Advance Risk Analysis of Nanoscale Materials in Washington, DC. In a July 9, 2014 Nanowerk Spotlight article,, Jo Anne Shatkin (President, Vireo Advisors) and Lorraine Sheremeta (Assistant Director, Ingenuity Lab, University of Alberta) tout the workshop in the context of describing new approaches to nanotoxicology research (Note: A link has been removed),

Engineered nanoscale materials (ENM or ‘nanomaterials’) offer the potential to create safer and more effective products through the use of smaller quantities of improved performance materials. Currently nanomaterials are used to improve the performance of life-saving drugs and medical technologies, to make renewable energy more efficient, to make value added products from industrial waste streams, to improve food, packaging, to lightweight materials used in transportation systems, and to improve many of the personal care products that we use every day. Nanomaterial manufacture and use is expected to increase over the coming years and despite the widespread use of nanomaterials in a variety of consumer products, we are only beginning to understand the impacts of these emerging materials on our health and the environment. To this end, the University of Alberta’s Ingenuity Lab is collaborating with the Society for Risk Analysis to evaluate the potential to use alternative test strategies (ATS) to improve our ability to assess nanomaterial toxicity and environmental impact.

Shatkin and Sheremeta describe toxicology tests and explain the importance of refining and improving these tests (from the article),

Standard in vivo toxicology test methods that depend heavily on the use of animals have long been used to assess chemical safety. [emphasis mine*] Existing and novel in vitro and in silico test methods provide important alternatives to in vivo animal testing for chemicals and potentially for ENM. Genotoxicity tests, for example, are used to assess the mutagenic potential of chemicals or nanomaterials in the replication of DNA in cells. Driven in part by increasing market and regulatory requirements for safer and more sustainable products, large international infrastructure has developed for creating, testing and validating in vitro test methods, and its use is expanding to chemical and nanomaterial assessment (NSF, 2007). The goals of reducing, refining and replacing animal testing (the commonly cited ‘three Rs’) – resonate with key and diverse stakeholders including animal rights groups, the bioethics community, the pharmaceutical industry, regulatory agencies and the broader public. [emphasis mine*]

Despite nearly a decade of effort in the conduct toxicology and exposure research to inform the assessment of health and environmental risks of nanomaterials, major gaps remain in the ability to understand and quantify risks. While there is now a large body of published data on carbon nanotubes and metal oxide nanoparticles, concern has been raised that speculation about nanomaterial risk has hardened into an assumption that there are ‘as-yet-to-be-discovered risks’ that we must identify and manage (Maynard, 2014) that demands extensive testing.

The authors describe ATS (alternative test strategies) in greater detail,

ATS approaches are regarded by many to have the potential for rapid screening of large numbers and types of materials. They can include a breadth of techniques including high throughput screening methods (HTS), high content screening, computational approaches, toxicogenomics, cell-based methods, in vitro assays and non-mammalian whole animal models. The emergence of ATS raises questions about how the results of these methods may be used for assessing the potential risks of ENM. For instance, ATS could be used in combination in a multiple models approach to evaluate new ENM in a number of rapid assays and compare with well-studied substances using in vivo testing; thereby identifying ENM for additional testing in a more strategic fashion than is possible through conventional testing approaches.

They also describe the current state of affairs with ATS,

In the United States, the U.S. ToxCast program has, as part of their 21st century toxicity screening program (NRC, 2007), tested 29 NMs with 62 in vitro test methods (Wang et al. 2013). Many researchers, including several from the University of Alberta, have proposed and developed ATS to include a variety of methods, some which are standardized for chemicals, and others which take advantage of developments including advanced biological mechanistic understanding, genomics, metabolomics, automation and informatics. However, these existing as well as emerging ATS have a short history with nanomaterials, and have not yet proven to be reliable for quantitative estimation of ENM risk. Still, several international efforts have developed ATS that have potential to be used for screening purposes, and to guide further testing priorities for regulatory decision making. The goal of the September [2014] workshop by the Society for Risk Analysis is to explore ways in which distinct ATS may be used for screening and prioritizing the need for more extensive testing of novel ENM.

The parties (including the authors of the article) involved in developing this risk workshop are listed, also mentioned are members of the international testing scene,

Lori Sheremeta, the Assistant Director of Ingenuity Lab in Edmonton Alberta and past Chair of the Society for Risk Analysis (SRA) Emerging Nanoscale Materials Specialty Group (ENMSG), is collaborating with U.S.-based nanomaterials risk expert Jo Anne Shatkin (an SRA Councilor and co-founder of the SRA ENMSG), Environment Canada, Health Canada, the SRA ENMSG and others on a Pilot Project with the Organization for Economic Co-operation and Development (OECD) Working Party on Manufactured Nanomaterials (WPMN) to develop a report on the State of the Science for ATS for nanomaterials, catalogue of existing and emerging ATS methods in a database; and develop a case study to inform workshop deliberations and expert recommendations.

…

There are many international efforts to develop, as well as to validate and standardize, these methods for chemicals, including organizations such as the US National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (ICCVAM), the European Union Reference Laboratory European Centre for the Validation of Alternative Methods (EURL ECVAM), the Japanese Center for the Validation of Alternative Methods (JacVAM), the Korean Centre for the Validation of Alternative Methods (KoCVAM) and the OECD. There is wide recognition that the diversity of NMs renders it impractical to use traditional animal testing to evaluate safety, hence there is significant interest in assessing the performance of both existing and emerging alternative testing strategies for NMs. Further, the EU directive REACH (Directive 2006/121/EC) requires replacing in vivo testing, and there is widespread popular agreement about the desire to limit animal testing. Finally, there is a need for more biologically informative toxicology methods (Hartung, 2010; Silbergeld et al, 2011; Landsiedel et al, 2009).

A list of the workshop objectives is offered  in the article,

The main objectives of the workshop are to:

assess the state of the science on HTS and ATS from a ‘multiple models’ perspective to identify areas of common findings from differing approaches, areas of greatest uncertainty, and priorities for follow up in applied research toward risk assessment of ENM;
evaluate the ability to use data from ATS/HTS methods for screening purposes – combining suites of assays and comparing well-studied substances to novel ones;

assess the ability to use a suite of ATS methods to amplify the Weight of Evidence;

characterize uncertainty associated with predictive relationships and propose strategies to address uncertainties;

elicit the perspectives of diverse stakeholders about the use of HTS/ATS for screening purposes in risk analysis of ENM; and

develop a set of recommendations for these alternative approaches to become more widely adopted for environmental, health and safety decision making about ENM across the product life cycle. The output of the workshop holds potential for transformation through risk screening approaches that promote safer and more sustainable material and technology development.

You can find more about the September 15-16, 2014 Workshop to Explore How a Multiple Models Approach can Advance Risk Analysis of Nanoscale Materials in Washington, DC here.

The text in the article is a bit rough. Some of the ideas and topics don’t follow each other logically. So, be prepared to spend a little time reading, Happily, there are references included with the article.

I last mentioned Jo Anne Shatkin here in the context of a 2013 paper on alternative test strategies (ATS) in an Aug. 22, 2013 posting. I think the most recent mention of Lorraine Sheremeta here is in a Jan. 11, 2010 posting about Canada, nanotechnology, and food.

Final note, I am hoping to get some more information about the workshop and ATS scene from Lorraine Sheremeta to be published in a subsequent posting.

* I added the emphases at 0830 hours PDT July 10, 2014.

Canadian government spending on science and technology is down for the fourth year in a row

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It seems there a steady downward trajectory where Canadian science and technology spending is concerned. Stephen Hui in a May 28, 2014 article for the Georgia Straight, breaks the latest news from Statistics Canada (Note: A link has been removed),

The Canadian government is expected to spend less money on science and technology in 2014-15 compared to the previous fiscal year, continuing a trend that began in 2011-12. [emphasis mine]

According to Statistics Canada, federal departments and agencies are projected to record $10.3 billion (all figures in current dollars) in science and tech expenditures in 2014-15, a decrease of 5.4 percent from 2013-14.

Federal science and tech spending peaked at $12 billion in 2010-11 and has declined every year since then.

In fact, an earlier July 30, 2013 news item in Huffington Post noted a decrease in the 2013-14 budget,

The federal agency says spending for the 2013-14 fiscal year is expected to decrease 3.3 per cent from the previous period, to $10.5 billion.

It adds research and development is expected to account for two-thirds of anticipated science and technology spending.

The finding is contained in Statistics Canada’s annual survey of all federal government departments and agencies believed to be performing or funding science and technology activities.

The survey, released Tuesday [July 2013], covers the period from Sept. 10, 2012 to Jan. 11, 2013.

Statistics Canada says spending on science and technology has been steadily decreasing since 2009-10. [emphasis mine]

According to Hui’s source, the Statistics Canada’s The Daily, May 28,2014: Federal government spending on science and technology, 2014/2015, the trend started in 2011/12. I’m not sure which specific Statistics Canada publication was the source for the Huffington Post’s start date for the decline.

Interestingly, the OECD (Organization for Economic Cooperation and Development) Science, Technology and Industry Scoreboard 2013 dates the decline to 2001. From my Oct. 30, 2013 posting (excerpted from the scorecard),

Canada is among the few OECD countries where R&D expenditure declined between 2000 and 2011 (Figure 1). This decline was mainly due to reduced business spending on R&D. It occurred despite relatively generous public support for business R&D, primarily through tax incentives. In 2011, Canada was amongst the OECD countries with the most generous tax support for R&D and the country with the largest share of government funding for business R&D being accounted for by tax credits (Figure 2). …

If I understand this rightly, Canadian business spending on R&D has been steadily declining for more than a decade and, since 2010 or so, Canadian government spending is also steadily declining. Does anyone else see this as a problem?

The contrast with Brazil is startling. From a June 2, 2014 Institute of Physics news release (also on EurekAlert but dated as June 1, 2014),

As Brazil gets set to host the 2014 FIFA World Cup this month amid concerns about the amount of public money being used to stage the world’s largest sporting event, Physics World‘s editorial team reveals in a new special report how physicists are taking full advantage of the four-fold increase in science funding that the government has invested over the past 10 years.

Since this news comes from the physics community, the news release focuses on physics-related developments,

Negotiations are currently under way to make Brazil an associate member of the CERN particle-physics lab in Geneva, while the country is also taking a leading role in the Pierre Auger Observatory – an international project based in Argentina designed to study ultrahigh-energy cosmic rays. [emphasis mine]

Building is also under way to create a world-leading synchrotron source, Sirius and Brazil is poised to become the first non-European member of the European Southern Observatory.

Carlos Henrique de Brito Cruz, a physicist at the University of Campinas and scientific director at FAPESP – one of Brazil’s most important funding agencies – told Physics World that the expectation is for Brazilian scientists to take a leadership role in such large research projects “and not just watch as mere participants”.

Considering the first graduate programmes in physics did not emerge in Brazilian universities until 1960, the rise to becoming one of the leading participants in international collaborations has been a rapid one.

The reputation of Brazilian physics has grown in line with a massive increase in science funding, which rose from R$12bn (about £3bn) in 2000 to R$50bn (around £13bn) in 2011.

Brazil’s spending on R&D now accounts for 1.2% of the gross domestic product and 40% of the total funding comes from companies.

The Brazilian Physical Society has around 6000 members comprising almost all research physicists in the country, who wrote around 25 000 research articles in international science journals between 2007 and 2010.

A lack of funding in the past had forced Brazilian scientists to focus on cheaper, theoretical research, but this has now changed and there is an almost even split between theory and experiment at universities.

Yet Brazil still suffers from several long-standing problems, the most significant being the poor standard of science education in high schools. A combination of low pay and lack of recognition makes physics teaching an unpopular choice of occupation despite attempts to tackle the problem.

Even those students who do see physics as a career option end up struggling and under-prepared for the rigours of an undergraduate physics course. Vitor de Souza, an astrophysicist at the Physics Institute at São Carlos, which is part of the University of São Paulo, told Physics World that of the 120 students who start a four-year physics degree at his university, only 10-20 actually graduate.

Another problem in Brazil is a fundamental disconnect between academic research and industrial development, with universities not sure how to handle spin-off firms and companies suspicious of universities.

More broadly, physicists feel that Brazilian society does not recognize the value of science, and that this can only be overcome when the physics community becomes more ambitious and more audacious.

You can find the special issue of Physics World here (it is open access).

As I noted in this May 30, 2014 posting (and elsewhere) featuring the new Agency of Science Communication, Technology and Innovation of Argentina (ACCTINA),,

The PCST [13th International Public Communication of Science and Technology Conference] international conference takes place every two years. The 2014 PCST conference took place in Salvador, Brazil. Conferences like this would seem to confirm the comments I made in a May 20, 2014 posting,

Returning to 2014, the [World Cup {soccer}] kickoff in Brazil (if successful) symbolizes more than an international athletic competition or a technical/medical achievement, this kick-off symbolizes a technological future for Brazil and its place on the world stage (despite the protests and social unrest) .

While the science and technology community in Brazil has its concerns, I imagine most Canadian scientists would thrill to being the recipients of the funding bonanza of 1.2%  of the gross domestic product. According to the Conference Board of Canada, research and development spending in Canada was 0.8% of GDP for 2011 (from the Conference Board of Canada’s Public R&D spending webpage),

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Did you notice, Canada the in 2011 was on the edge of getting a C grade along with the US? Meanwhile, if Brazil was listed, it would get top marks.

The question as to how much money is not enough for research and development (R&D) spending is complex and I don’t think it’s easily answered but it would be nice to see some discussion.