Tag Archives: SciArt

The sense of beauty: an art/science film about CERN, the European Particle Physics Laboratory, in Vancouver, Canada; art/sci September in Toronto (Canada), a science at the bar night in Vancouver (Canada), and a festival in Calgary (Canada)

Compared to five or more years ago, there’s a lollapalooza of art/sci (or sciart) events coming up in September 2018. Of course, it’s helpful if you live in or are visiting Toronto or Vancouver or Calgary at the right time.  All of these events occur from mid September (roughly) to the end of September. In no particular date order:

Sense of beauty in Vancouver

The September 10, 2018 Dante Alighieri Society of British Columbia invitation (received via email) offered more tease than information. Happily, the evite webpage for “The Sense of Beauty: Art and Science at CERN” (2017) by Valerio Jalongo filled in the details,

The Dante Alighieri Society of British Columbia

Invites you to the screening of the documentary

“The Sense of Beauty: Art and Science at CERN” (2017) by Valerio Jalongo

TUESDAY, SEPTEMBER 25, 2018 at 6:30 pm

The CINEMATHEQUE – 1131 Howe Street, Vancouver

Duration of film: 75’. Director in attendance; Q&A with the film director to follow the screening

Free Admission

RSVP: info@dantesocietybc.ca

Director Jalongo will discuss the making of his documentary in a seminar open to the public on September 24 (1:00-2:30 pm) at UBC  [University of British Columbia] (Buchanan Penthouse, *1866 Main Maill, Block C, 5th floor*, Vancouver).

The Sense of Beauty is the story of an unprecedented experiment that involves scientists from throughout the world collaborating around the largest machine ever constructed by human beings: the LHC (Large Hadron Collider). As the new experiment at CERN proceeds in its exploration of the mysterious energy that animates the universe, scientists and artists guide us towards the shadow line where science and art, in different ways, pursue truth and beauty.

Some of these men and women believe in God, while others believe only in experiment and doubt. But in their search for truth they are all alert to an elusive sixth – or seventh – sense: the sense of beauty. An unmissable opportunity for lovers of science, of beauty, or of both.

Rome-born Valerio Jalongo is a teacher, screenwriter and director who works in cinema and TV, for which he created works of fiction and award-winning documentaries. Among them: Sulla mia pelle (On My Skin, 2003) and La scuola è finita (2010), starring Valeria Golino, on the difficulties facing public schools in Italy.

This event is presented by the Dante Alighieri Society of BC in collaboration with the Consulate General of Italy in Vancouver and in association with ARPICO (www.arpico.ca), the Society of Italian Researchers and Professionals in Western Canada.

RSVP: info@dantesocietybc.ca

I searched for more information both about the film and about the seminar at UBC. I had no luck with the UBC seminar but I did find more about the film. There’s an April (?) 2017 synopsis by Luciano Barisone on the Vision du Réel website,

From one cave to another. In prehistoric times, human beings would leave paintings in caves to show their amazement and admiration for the complexity of the world. These reproductions of natural forms were the results of an act of creation and also of mystical gestures which appropriated the soul of things. In another gigantic and modern den, the immense CERN laboratory, the same thing is happening today, a combination of enthralled exploration of the cosmos and an attempt to control it. Valerio Jalongo’s film tackles the big questions that have fascinated poets, artists and philosophers since the dawn of time. Who are we? Where do we come from? Where are we going? The scientists at CERN attempt to answer them through machines that explore matter and search for the origins of life. In their conversations or their words to camera, the meaning of existence thus seems to become a pure question of the laws of physics and mathematical formulae. If only for solving the mystery of the universe a sixth sense is necessary. That of beauty…

There’s also a February 5, 2018 essay by Stefano Caggiano for Interni, which uses a description of the film to launch into a paean to Italian design,

The success of the documentary The Sense of Beauty by Valerio Jalongo, which narrates the ‘aesthetic’ side of the physicists at CERN when faced with the fundamental laws of nature, proves that the yearning for beauty is not just an aspect of art, but something shared by all human efforts to interpret reality.

It is no coincidence that the scientists themselves define the LHC particle accelerator (27 km) as a grand machine for beauty, conceived to investigate the meaning of things, not to perform some practical function. In fact, just as matter can be perceived only through form, and form only if supported by matter (Aristotle already understood this), so the laws of physics can be glimpsed only when they are applied to reality.

This is why in the Large Hadron Collider particles are accelerated to speeds close to that of light, reconstructing the matter-energy conditions just a few instants after the Big Bang. Only in this way is it possible to glimpse the hidden fundamental laws of the universe. It is precisely this evanescence that constitutes ‘beauty.’

The quivering of the form that reveals itself in the matter that conceals it, and which – given the fact that everything originates in the Big Bang – is found everywhere, in the most faraway stars and the closest objects: you just have to know how to prove it, grasp it, how to wait. Because this is the only way to establish relations with beauty: not perceiving it but awaiting it. Respecting its way of offering itself, which consists in denying itself.

Charging the form of an object with this sensation of awaiting, then, means catalyzing the ultimate and primary sense of beauty. And it is what is held in common by the work of the five Italian designers nominated for the Rising Talent Awards of Maison & Object 2018 (with Kensaku Oshiro as the only non-Italian designer, though he does live and work in Milan).

There’s a trailer (published by CERN on November 7, 2017,

It’s in both Italian and English with subtitles throughout, should you need them.

*The address for the Buchanan Penthouse was corrected from: 2329 West Mall to 1866 Main Maill, Block C, 5th floor on Sept. 17, 2018.

Toronto’s ArtSci Salon at Nuit Blanche, Mycology, Wild Bees and Art+Tech!

From a Tuesday, September 11, 2018 Art/Sci Salon announcement (received via email),

Baba Yaga Collective and ArtSci Salon Present:
Chaos Fungorum

In 1747, Carl Linnaeus, known as the “father of taxonomy”, observed
that the seeds of fungus moved in water like fish until “..by a law of
nature thus far unheard of and surpassing all human understanding..,”
they changed back to plant in their adult life.

He proceeded to include fungi in the new genus of “Chaos”. But why
delimiting fungi within categories and boundaries when it is exactly
their fluidity that make them so interesting?

Chaos Fungorum draws on the particular position occupied by fungi and
other hybrid organisms: neither plant nor animal, fungi extend across,
and can entertain, communications and collaborations between animal,
human and industrial realms.

Mixing different artistic practices and media, the artists featured in
this exhibition seek to move beyond rigid comprehensions of the living
by working with, rather than merely shaping, sculpting and manipulating
plants, microorganisms and fungi. Letting the non-human speak is to move
away from an anthropocentric approach to the world: it not only opens to
new rewarding artistic practices, but it also fosters new ideas of
sustainable coexistence, new unusual life collaborations and
adaptations, and new forms of communications and languages.

THE EXHIBITION
September 26 – October 7, 2018

Baba Yaga Collective 906 Queen Street West @Crawford, Toronto

info@babayagacollective.ca

FEATURING

BIO.CHROME COLLECTIVE
Robyn Crouch • Mellissa Fisher • Shavon Madden
Tracy Maurice • Tosca Teran • Alexis Williams

SPECIAL GUEST
Whitefeather Hunter

SPECIAL NUIT BLANCHE OPENING RECEPTION
September 29
6:00 – 9:00 pm

6:30pm: Artsci Salon introduction with Roberta Buiani and Stephen Morris
rethinking categories and the “non-human” in art and science

Followed by artist remarks.
Scientists from the University of Toronto will act as respondent.

9:30pm onward: Tosca Teran & Andrei Gravelle of Nanotopia [emphasis mine]

BIO-SONIFICATIONS: NON-HUMAN COLLABORATIONS Mycelium to MIDI •

Midnight Mushroom music live performance

This Special program is co-presented by The Baba Yaga Collective and
ArtSci Salon. For more information contact artscisalon@gmail.com
https://www.facebook.com/events/1763778620414561/

 All the Buzz on Wild Bee Club!
Summer Speaker Series

Wed Sept 19 at 7pm
High Park Nature Centre,
All the Buzz on Wild Bee Club! – Summer Speaker Series

The speaker series will feature the club’s biologist/leader SUSAN FRYE.
A major component of this club will use the SONIC SOLITARIES AUDIO BEE
CABINET  – an observable nest site for bees in OURSpace – to encompass a
sensory experience with stem nesting bees and wasps, and to record
weekly activity at the cabinet. Pairing magnified views in tandem with
amplified sound via headphones, the cabinet facilitates an enhanced
perception of its tiny inhabitants: solitary bees and wasps and other
nest biota in action, up close. As citizen scientists, we can gather and
record observations to compile them into a database that will contribute
to our growing understanding of native bees, the native (and non-native)
plants they use for food and nest material sources, their co-evolution,
and how pollination in a park and restored habitat setting is
facilitated by native bees.

Fri, Sept 21, 8pm
Music Gallery, 918 Bathurst (their new location) –
Trio Wow & Flutter
with Bea Labikova, fujara, saxophones,
Kayla Milmine-Abbott, soprano saxophone,
Sarah Peebles, shō, cracklebox, amplifiers.

Call for Participants: Art+Tech Jam

ChangeUp’s Art+Tech Jam
September 21-23

This three days event will unite a diverse group of artists and
technologists in an intensive, collaborative three-day creation period
and culminating showcase (public exhibition and interdisciplinary rave).

ChangeUo is currently accepting applicants from tech and arts/culture
spaces of all ages, backgrounds, and experience levels.
Limited spots available.
For more information and to apply
https://tinyurl.com/changeup-artsorg

I looked up Nanotopia and found it on SoundCloud. Happy listening!

Et Al III (the ultimate science bar night in Vancouver) and more

A September 12, 2018 Curiosity Collider announcement (received via email) reveals details about the latest cooperative event/bar night put on by three sciencish groups,

Curiosity Collider is bringing art + science to Vancouver’s Ultimate Bar Science Night with Nerd Nite & Science Slam

Do you enjoy learning about science in a casual environment? This is the third year that Curiosity Collider is part of Et al, the Ultimate Bar Science Night where we bring together awesome speakers and activities. Come and enjoy Curiosity Collider’s segment on quantum physics with Spoken Word Poet Angelica Poversky, Physicist James Day, and CC’s own Creative Director Char Hoyt.

When: Drinks and mingling start at 6:30pm. Presentations start at 7:30pm.
Where: Rio Theatre, 1660 E Broadway, Vancouver, BC V5N 1W1
Cost: $15-20 via Eventbrite and at the door. Proceeds will be used to cover the cost of running this event, and to fund future science bar events.

Special Guest talk by Dr. Carin Bondar – Biologist with a Twist!

Dr. Carin Bondar is a biologist, author and philosopher. Bondar is author of the books Wild Sex and Wild Moms (Pegasus). She is the writer and host of an online series based on her books which have garnered over 100,000,000 views. Her TED talk on the subject has nearly 3 million views. She is host of several TV series including Worlds Oddest Animal Couples (Animal Planet, Netflix), Stephen Hawking’s Brave New World (Discovery World HD, National Geographic) and Outrageous Acts of Science (The Science Channel). Bondar is an adventurer and explorer, having discovered 11 new species of beetles and snails in the remote jungles of Borneo. Bondar is also a mom of 4 kids, two boys and two girls.

Follow updates on twitter via @ccollider or #ColliderCafe. This event is part of the Science Literacy Week celebration across Canada.

Head to the Facebook event page – let us know you are coming and share this event with others!

Looking for more Art+Science in Vancouver?
For more Vancouver art+science events, visit the Curiosity Collider events calendar.

Devoted readers 🙂 will note that the Vancouver Biennale’s Curious Imaginings show was featured here in a June 18, 2018 post and mentioned more recently in the context of a September 11, 2018 post on xenotransplantation.

Finally for this section, special mention to whomever wrote up the ‘bar night’ description on Eventbrite,

Et Al III: The Ultimate Bar Science Night Curiosity Collider + Nerd Nite Vancouver + Science Slam Canada

POSTER BY: Armin Mortazavi IG:@Armin.Scientoonist

Et Al III: The Ultimate Bar Science Night

Curiosity Collider + Nerd Nite Vancouver + Science Slam Canada

Special Guest talk by Dr. Carin Bondar – Biologist with a Twist!

6:30pm – Doors open
6:30-7:30 Drinks, Socializing, Nerding
7:30pm-945pm Stage Show with two intermissions

You like science? You like drinking while sciencing? In Vancouver there are many options to get educated and inspired through science, art, and culture in a casual bar setting outside of universities. There’s Nerd Nite which focuses on nerdy lectures in the Fox Cabaret, Curiosity Collider which creates events that bring together artists and scientists, and Science Slam, a poetry-slam inspired science communication competition!

In this third installment of Et Al, we’re making the show bigger than ever. We want people to know all about the bar science nights in Vancouver, but we also want to connect all you nerds together as we build this community. We encourage you to COME DRESSED AS YOUR FAVOURITE SCIENTIST. We will give away prizes to the best costumes, plus it’s a great ice breaker. We’re also encouraging science based organizations to get involved in the show by promoting your institution. Contact Kaylee or Michael at vancouver@nerdnite.com if your science organization would like to contribute to the show with some giveaways, you will get a free ticket, if you don’t have anything to give away, contact us anyway, we want this to be a celebration of science nights in Vancouver!

BIOS

CARIN BONDAR
Dr. Carin Bondar is a biologist, author and philosopher. Bondar is author of the books Wild Sex and Wild Moms (Pegasus). She is writer and host of online series based on her books (Wild Sex and Wild Moms) which have garnered over 100,000,000 views. Her TED talk on the subject has nearly 3 million views. She is host of several TV series including Worlds Oddest Animal Couples (Animal Planet, Netflix), Stephen Hawking’s Brave New World (Discovery World HD, National Geographic) and Outrageous Acts of Science (The Science Channel). Bondar is an adventurer and explorer, having discovered 11 new species of beetles and snails in the remote jungles of Borneo. Bondar is also a mom of 4 kids, two boys and two girls.

Curiosity Collider Art Science Foundation promotes interdisciplinary collaborations that capture natural human curiosity. At the intersection of art, culture, technology, and humanity are innovative ways to communicate the daily relevance of science. Though exhibitions, performance events and our quarterly speaker event, the Collider Cafe we help create new ways to experience science.

NERD NITE
In our opinion, there has never been a better time to be a Nerd! Nerd Nite is an event which is currently held in over 60 cities worldwide! The formula for each Nerd Nite is pretty standard – 20 minute presentations from three presenters each night, in a laid-back environment with lots to learn, and lots to drink!

SCIENCE SLAM
Science Slam YVR is a community outreach organization committed to supporting and promoting science communication in Vancouver. Our Science Slams are informal competitions that bring together researchers, students, educators, and communicators to share interesting science in creative ways. Every event is different, with talks, poems, songs, dances, and unexpected surprises. Our only two rules? Each slammer has 5 minutes, and no slideshows are allowed! Slammers come to share their science, and the judges and audience decide their fate. Who will take away the title of Science Slam champion?

That’s a pretty lively description. You can get tickets here.

Calgary’s Beakerhead

An art, science, and engineering festival in Calgary, Alberta, Beakerhead opens on September 19, 2018 and runs until September 23, 2018. Here’s more from the 2018 online programme announcement made in late July (?) 2018,

Giant Dung Beetle, Zorb Ball Racers, Heart Powered Art and More Set to Explode on Calgary Streets!

Quirky, fun adventures result when art, science and engineering collide at Beakerhead September 19 – 23, 2018.

In just seven weeks, enormous electric bolts will light up the sky in downtown Calgary when a crazy cacophony of exhibits and events takes over the city. The Beakerhead crew is announcing the official program lineup with tickets now available online for all ticketed events. This year’s extravaganza will include remarkable spectacles of art and science, unique activities, and more than 50 distinct events – many of which are free, but still require registration to get tickets.

The Calgary-born smash up of art, science and engineering is in its sixth year. Last year, more than 145,000 people participated in Beakerhead and organizers are planning to top that number in 2018.

“Expect conversations that start with “wow!” says Mary Anne Moser, President and Co-founder of Beakerhead. “This year’s lineup includes a lot of original concepts, special culinary events, dozens of workshops, shows and and tours.”

Beakerhead events take place indoors and out. Beakernight is science’s biggest ticketed street party and tickets are now on sale.

Highlights of Beakerhead 2018:

  • Light up the Night: Giant electric bolts will light up the night sky thanks to two 10-metre Tesla Coils built by a team of artists and engineers.
  • Lunch Without Light: This special Dark Table dining experience is led by a famous broadcaster and an esteemed neuroscientist.
  • Beakereats and Beakerbar: Dining is a whole new experience when chef and bartender become scientist! Creative Calgary chefs and mixologists experiment with a new theme in 2018: canola.
  • Four to Six on Fourth: Blocks of open-air experimentation including a human-sized hamster wheel, artists, performers, and hands-on or feet-on experiences like walking on liquid.
  • Beacons: This series of free neighbourhood installations is completely wild! There’s everything from a giant dung beetle to a 3.5 metre lotus that lights up with your heart beat.
  • Workshops: Learn the art of animation, understand cryptocurrency, meet famous scientists and broadcasters, make organic facial oil or a vegan carrot cake and much more.
  • Zorbathon: Get inside a zorb and cavort with family and friends in an oversized playground. Participate in rolling races, bump-a-thons, obstacle courses. Make a day of it.

Beakerhead takes place September 19 – 23, 2018 with the ticketed Beakernight on Saturday, September 22 at Fort Calgary.

Here’s a special shout out to Shaskatchewan`s Jean-Sébastien Gauthier and Brian F. Eames (featured here in a February 16, 2018 posting) and their free ‘Within Measure’ Sept. 19 – 23, 2018 event at Beakerhead.

That’s all folks! For now, that is.

Xenotransplantation—organs for transplantation in human patients—it’s a business and a science

The last time (June 18, 2018 post) I mentioned xenotransplantation (transplanting organs from one species into another species; see more here), it was in the context of an art/sci (or sciart) event coming to Vancouver (Canada).,

Patricia Piccinini’s Curious Imaginings Courtesy: Vancouver Biennale [downloaded from http://dailyhive.com/vancouver/vancouver-biennale-unsual-public-art-2018/]

The latest edition of the Vancouver Biennale was featured in a June 6, 2018 news item on the Daily Hive (Vancouver),

Melbourne artist Patricia Piccinini’s Curious Imaginings is expected to be one of the most talked about installations of the exhibit. Her style of “oddly captivating, somewhat grotesque, human-animal hybrid creature” is meant to be shocking and thought-provoking.

Piccinini’s interactive [emphasis mine] experience will “challenge us to explore the social impacts of emerging biotechnology and our ethical limits in an age where genetic engineering and digital technologies are already pushing the boundaries of humanity.”

Piccinini’s work will be displayed in the 105-year-old Patricia Hotel in Vancouver’s Strathcona neighbourhood. The 90-day ticketed exhibition [emphasis mine] is scheduled to open this September [2018].

(The show opens on Sept. 14, 2018.)

At the time, I had yet to stumble across Ingfei Chen’s thoughtful dive into the topic in her May 9, 2018 article for Slate.com,

In the United States, the clock is ticking for more than 114,700 adults and children waiting for a donated kidney or other lifesaving organ, and each day, nearly 20 of them die. Researchers are devising a new way to grow human organs inside other animals, but the method raises potentially thorny ethical issues. Other conceivable futuristic techniques sound like dystopian science fiction. As we envision an era of regenerative medicine decades from now, how far is society willing to go to solve the organ shortage crisis?

I found myself pondering this question after a discussion about the promises of stem cell technologies veered from the intriguing into the bizarre. I was interviewing bioengineer Zev Gartner, co-director and research coordinator of the Center for Cellular Construction at the University of California, San Francisco, about so-called organoids, tiny clumps of organlike tissue that can self-assemble from human stem cells in a Petri dish. These tissue bits are lending new insights into how our organs form and diseases take root. Some researchers even hope they can nurture organoids into full-size human kidneys, pancreases, and other organs for transplantation.

Certain organoid experiments have recently set off alarm bells, but when I asked Gartner about it, his radar for moral concerns was focused elsewhere. For him, the “really, really thought-provoking” scenarios involve other emerging stem cell–based techniques for engineering replacement organs for people, he told me. “Like blastocyst complementation,” he said.

Never heard of it? Neither had I. Turns out it’s a powerful new genetic engineering trick that researchers hope to use for growing human organs inside pigs or sheep—organs that could be genetically personalized for transplant patients, in theory avoiding immune-system rejection problems. The science still has many years to go, but if it pans out, it could be one solution to the organ shortage crisis. However, the prospect of creating hybrid animals with human parts and killing them to harvest organs has already raised a slew of ethical questions. In 2015, the National Institutes of Health placed a moratorium on federal funding of this nascent research area while it evaluated and discussed the issues.

As Gartner sees it, the debate over blastocyst complementation research—work that he finds promising—is just one of many conversations that society needs to have about the ethical and social costs and benefits of future technologies for making lifesaving transplant organs. “There’s all these weird ways that we could go about doing this,” he said, with a spectrum of imaginable approaches that includes organoids, interspecies organ farming, and building organs from scratch using 3D bioprinters. But even if it turns out we can produce human organs in these novel ways, the bigger issue, in each technological instance, may be whether we should.

Gartner crystallized things with a downright creepy example: “We know that the best bioreactor for tissues and organs for humans are human beings,” he said. Hypothetically, “the best way to get you a new heart would be to clone you, grow up a copy of yourself, and take the heart out.” [emphasis mine] Scientists could probably produce a cloned person with the technologies we already have, if money and ethics were of no concern. “But we don’t want to go there, right?” he added in the next breath. “The ethics involved in doing it are not compatible with who we want to be as a society.”

This sounds like Gartner may have been reading some science fiction, specifically, Lois McMaster Bujold and her Barrayar series where she often explored the ethics and possibilities of bioengineering. At this point, some of her work seems eerily prescient.

As for Chen’s article, I strongly encourage you to read it in its entirety if you have the time.

Medicine, healing, and big money

At about the same time, there was a May 31, 2018 news item on phys.org offering a perspective from some of the leaders in the science and the business (Note: Links have been removed),

Over the past few years, researchers led by George Church have made important strides toward engineering the genomes of pigs to make their cells compatible with the human body. So many think that it’s possible that, with the help of CRISPR technology, a healthy heart for a patient in desperate need might one day come from a pig.

“It’s relatively feasible to change one gene in a pig, but to change many dozens—which is quite clear is the minimum here—benefits from CRISPR,” an acronym for clustered regularly interspaced short palindromic repeats, said Church, the Robert Winthrop Professor of Genetics at Harvard Medical School (HMS) and a core faculty member of Harvard’s Wyss Institute for Biologically Inspired Engineering. Xenotransplantation is “one of few” big challenges (along with gene drives and de-extinction, he said) “that really requires the ‘oomph’ of CRISPR.”

To facilitate the development of safe and effective cells, tissues, and organs for future medical transplantation into human patients, Harvard’s Office of Technology Development has granted a technology license to the Cambridge biotech startup eGenesis.

Co-founded by Church and former HMS doctoral student Luhan Yang in 2015, eGenesis announced last year that it had raised $38 million to advance its research and development work. At least eight former members of the Church lab—interns, doctoral students, postdocs, and visiting researchers—have continued their scientific careers as employees there.

“The Church Lab is well known for its relentless pursuit of scientific achievements so ambitious they seem improbable—and, indeed, [for] its track record of success,” said Isaac Kohlberg, Harvard’s chief technology development officer and senior associate provost. “George deserves recognition too for his ability to inspire passion and cultivate a strong entrepreneurial drive among his talented research team.”

The license from Harvard OTD covers a powerful set of genome-engineering technologies developed at HMS and the Wyss Institute, including access to foundational intellectual property relating to the Church Lab’s 2012 breakthrough use of CRISPR, led by Yang and Prashant Mali, to edit the genome of human cells. Subsequent innovations that enabled efficient and accurate editing of numerous genes simultaneously are also included. The license is exclusive to eGenesis but limited to the field of xenotransplantation.

A May 30, 2018 Harvard University news release by Caroline Petty, which originated the news item, explores some of the issues associated with incubating humans organs in other species,

The prospect of using living, nonhuman organs, and concerns over the infectiousness of pathogens either present in the tissues or possibly formed in combination with human genetic material, have prompted the Food and Drug Administration to issue detailed guidance on xenotransplantation research and development since the mid-1990s. In pigs, a primary concern has been that porcine endogenous retroviruses (PERVs), strands of potentially pathogenic DNA in the animals’ genomes, might infect human patients and eventually cause disease. [emphases mine]

That’s where the Church lab’s CRISPR expertise has enabled significant advances. In 2015, the lab published important results in the journal Science, successfully demonstrating the use of genome engineering to eliminate all 62 PERVs in porcine cells. Science later called it “the most widespread CRISPR editing feat to date.”

In 2017, with collaborators at Harvard, other universities, and eGenesis, Church and Yang went further. Publishing again in Science, they first confirmed earlier researchers’ fears: Porcine cells can, in fact, transmit PERVs into human cells, and those human cells can pass them on to other, unexposed human cells. (It is still unknown under what circumstances those PERVs might cause disease.) In the same paper, they corrected the problem, announcing the embryogenesis and birth of 37 PERV-free pigs. [Note: My July 17, 2018 post features research which suggests CRISPR-Cas9 gene editing may cause greater genetic damage than had been thought.]

“Taken together, those innovations were stunning,” said Vivian Berlin, director of business development in OTD, who manages the commercialization strategy for much of Harvard’s intellectual property in the life sciences. “That was the foundation they needed, to convince both the scientific community and the investment community that xenotransplantation might become a reality.”

“After hundreds of tests, this was a critical milestone for eGenesis — and the entire field — and represented a key step toward safe organ transplantation from pigs,” said Julie Sunderland, interim CEO of eGenesis. “Building on this study, we hope to continue to advance the science and potential of making xenotransplantation a safe and routine medical procedure.”

Genetic engineering may undercut human diseases, but also could help restore extinct species, researcher says. [Shades of the Jurassic Park movies!]

It’s not, however, the end of the story: An immunological challenge remains, which eGenesis will need to address. The potential for a patient’s body to outright reject transplanted tissue has stymied many previous attempts at xenotransplantation. Church said numerous genetic changes must be achieved to make porcine organs fully compatible with human patients. Among these are edits to several immune functions, coagulation functions, complements, and sugars, as well as the PERVs.

“Trying the straight transplant failed almost immediately, within hours, because there’s a huge mismatch in the carbohydrates on the surface of the cells, in particular alpha-1-3-galactose, and so that was a showstopper,” Church explained. “When you delete that gene, which you can do with conventional methods, you still get pretty fast rejection, because there are a lot of other aspects that are incompatible. You have to take care of each of them, and not all of them are just about removing things — some of them you have to humanize. There’s a great deal of subtlety involved so that you get normal pig embryogenesis but not rejection.

“Putting it all together into one package is challenging,” he concluded.

In short, it’s the next big challenge for CRISPR.

Not unexpectedly, there is no mention of the CRISPR patent fight between Harvard/MIT’s (Massachusetts Institute of Technology) Broad Institute and the University of California at Berkeley (UC Berkeley). My March 15, 2017 posting featured an outcome where the Broad Institute won the first round of the fight. As I recall, it was a decision based on the principles associated with King Solomon, i.e., the US Patent Office, divided the baby and UCBerkeley got the less important part of the baby. As you might expect the decision has been appealed. In an April 30, 2018 piece, Scientific American reprinted an article about the latest round in the fight written by Sharon Begley for STAT (Note: Links have been removed),

All You Need to Know for Round 2 of the CRISPR Patent Fight

It’s baaaaack, that reputation-shredding, stock-moving fight to the death over key CRISPR patents. On Monday morning in Washington, D.C., the U.S. Court of Appeals for the Federal Circuit will hear oral arguments in University of California v. Broad Institute. Questions?

How did we get here? The patent office ruled in February 2017 that the Broad’s 2014 CRISPR patent on using CRISPR-Cas9 to edit genomes, based on discoveries by Feng Zhang, did not “interfere” with a patent application by UC based on the work of UC Berkeley’s Jennifer Doudna. In plain English, that meant the Broad’s patent, on using CRISPR-Cas9 to edit genomes in eukaryotic cells (all animals and plants, but not bacteria), was different from UC’s, which described Doudna’s experiments using CRISPR-Cas9 to edit DNA in a test tube—and it was therefore valid. The Patent Trial and Appeal Board concluded that when Zhang got CRISPR-Cas9 to work in human and mouse cells in 2012, it was not an obvious extension of Doudna’s earlier research, and that he had no “reasonable expectation of success.” UC appealed, and here we are.

For anyone who may not realize what the stakes are for these institutions, Linda Williams in a March 16, 1999 article for the LA Times had this to say about universities, patents, and money,

The University of Florida made about $2 million last year in royalties on a patent for Gatorade Thirst Quencher, a sports drink that generates some $500 million to $600 million a year in revenue for Quaker Oats Co.

The payments place the university among the top five in the nation in income from patent royalties.

Oh, but if some people on the Gainesville, Fla., campus could just turn back the clock. “If we had done Gatorade right, we would be getting $5 or $6 million (a year),” laments Donald Price, director of the university’s office of corporate programs. “It is a classic example of how not to handle a patent idea,” he added.

Gatorade was developed in 1965 when many universities were ill equipped to judge the commercial potential of ideas emerging from their research labs. Officials blew the university’s chance to control the Gatorade royalties when they declined to develop a professor’s idea.

The Gatorade story does not stop there and, even though it’s almost 20 years old, this article stands the test of time. I strongly encourage you to read it if the business end of patents and academia interest you or if you would like to develop more insight into the Broad Institute/UC Berkeley situation.

Getting back to the science, there is that pesky matter of diseases crossing over from one species to another. While, Harvard and eGenesis claim a victory in this area, it seems more work needs to be done.

Infections from pigs

An August 29, 2018 University of Alabama at Birmingham news release (also on EurekAlert) by Jeff Hansen, describes the latest chapter in the quest to provide more organs for transplantion,

A shortage of organs for transplantation — including kidneys and hearts — means that many patients die while still on waiting lists. So, research at the University of Alabama at Birmingham and other sites has turned to pig organs as an alternative. [emphasis mine]

Using gene-editing, researchers have modified such organs to prevent rejection, and research with primates shows the modified pig organs are well-tolerated.

An added step is needed to ensure the safety of these inter-species transplants — sensitive, quantitative assays for viruses and other infectious microorganisms in donor pigs that potentially could gain access to humans during transplantation.

The U.S. Food and Drug Administration requires such testing, prior to implantation, of tissues used for xenotransplantation from animals to humans. It is possible — though very unlikely — that an infectious agent in transplanted tissues could become an emerging infectious disease in humans.

In a paper published in Xenotransplantation, Mark Prichard, Ph.D., and colleagues at UAB have described the development and testing of 30 quantitative assays for pig infectious agents. These assays had sensitivities similar to clinical lab assays for viral loads in human patients. After validation, the UAB team also used the assays on nine sows and 22 piglets delivered from the sows through caesarian section.

“Going forward, ensuring the safety of these organs is of paramount importance,” Prichard said. “The use of highly sensitive techniques to detect potential pathogens will help to minimize adverse events in xenotransplantation.”

“The assays hold promise as part of the screening program to identify suitable donor animals, validate and release transplantable organs for research purposes, and monitor transplant recipients,” said Prichard, a professor in the UAB Department of Pediatrics and director of the Department of Pediatrics Molecular Diagnostics Laboratory.

The UAB researchers developed quantitative polymerase chain reaction, or qPCR, assays for 28 viruses sometimes found in pigs and two groups of mycoplasmas. They established reproducibility, sensitivity, specificity and lower limit of detection for each assay. All but three showed features of good quantitative assays, and the lower limit of detection values ranged between one and 16 copies of the viral or bacterial genetic material.

Also, the pig virus assays did not give false positives for some closely related human viruses.

As a start to understanding the infectious disease load in normal healthy animals and ensuring the safety of pig tissues used in xenotransplantation research, the researchers then screened blood, nasal swab and stool specimens from nine adult sows and 22 of their piglets delivered by caesarian section.

Mycoplasma species and two distinct herpesviruses were the most commonly detected microorganisms. Yet 14 piglets that were delivered from three sows infected with either or both herpesviruses were not infected with the herpesviruses, showing that transmission of these viruses from sow to the caesarian-delivery piglet was inefficient.

Prichard says the assays promise to enhance the safety of pig tissues for xenotransplantation, and they will also aid evaluation of human specimens after xenotransplantation.

The UAB researchers say they subsequently have evaluated more than 300 additional specimens, and that resulted in the detection of most of the targets. “The detection of these targets in pig specimens provides reassurance that the analytical methods are functioning as designed,” said Prichard, “and there is no a priori reason some targets might be more difficult to detect than others with the methods described here.”

As is my custom, here’s a link to and a citation for the paper,

Xenotransplantation panel for the detection of infectious agents in pigs by Caroll B. Hartline, Ra’Shun L. Conner, Scott H. James, Jennifer Potter, Edward Gray, Jose Estrada, Mathew Tector, A. Joseph Tector, Mark N. Prichard. Xenotransplantaion Volume 25, Issue 4 July/August 2018 e12427 DOI: https://doi.org/10.1111/xen.12427 First published: 18 August 2018

This paper is open access.

All this leads to questions about chimeras. If a pig is incubating organs with human cells it’s a chimera but then means the human receiving the organ becomes a chimera too. (For an example, see my Dec. 22, 2013 posting where there’s mention of a woman who received a trachea from a pig. Scroll down about 30% of the way.)

What is it to be human?

A question much beloved of philosophers and others, the question seems particularly timely with xenotransplantion and other developments such neuroprosthetics (cyborgs) and neuromorphic computing (brainlike computing).

As I’ve noted before, although not recently, popular culture offers a discourse on these issues. Take a look at the superhero movies and the way in which enhanced humans and aliens are presented. For example, X-Men comics and movies present mutants (humans with enhanced abilities) as despised and rejected. Video games (not really my thing but there is the Deus Ex series which has as its hero, a cyborg also offer insight into these issues.

Other than popular culture and in the ‘bleeding edge’ arts community, I can’t recall any public discussion on these matters arising from the extraordinary set of technologies which are being deployed or prepared for deployment in the foreseeable future.

(If you’re in Vancouver (Canada) from September 14 – December 15, 2018, you may want to check out Piccinini’s work. Also, there’s ” NCSU [North Carolina State University] Libraries, NC State’s Genetic Engineering and Society (GES) Center, and the Gregg Museum of Art & Design have issued a public call for art for the upcoming exhibition Art’s Work in the Age of Biotechnology: Shaping our Genetic Futures.” from my Sept. 6, 2018 posting. Deadline: Oct. 1, 2018.)

At a guess, there will be pushback from people who have no interest in debating what it is to be human as they already know, and will find these developments, when they learn about them, to be horrifying and unnatural.

Pancakes & booze (underground) art show on Sept. 28, 2018 in Toronto and North Carolina’s public call for art for the upcoming exhibition Art’s Work in the Age of Biotechnology: Shaping our Genetic Futures.

Pancakes & booze

From an August 12, 2018 Art/Sci Salon announcement (received via email),

Toronto — Batter sizzles, beer foams, and bare flesh is slathered in paint as gawkers look on. Indie musicians and DJs thunder sound waves off the canvas-lined, graffiti-strewn walls. Revelers stuff their faces with endless pancakes.

What is this, some type of hipster themed IHOP? A Lady Gaga video? Bansky’s mom’s basement? Nah, it’s the Pancakes & Booze Art Show – the hottest pop-up traveling art event in all the land.

This is no stuffy wine-and-cheese, someone-gag-me-with-a-cocktail-napkin gallery. It’s an innovative reimagining of the art show concept, as DIY art movement mayhem. Up-and-coming artists strut and sell their stuff in a freeverse, electric funhouse of mayhem.

You know you want to come, right? Hit me up so we can talk about ways to convince your editor to pay you to visit the show and maybe relax that no-alcohol-on-the-job policy. Hell, even bring your boss along If you like.

WHAT: Pancakes & Booze Art Show: Over 80 emerging artists showcasing their hottest work in a Warhol-style, anything-goes, massive warehouse environment–live music, body painting, multimedia displays, and FREE pancakes!   The show originated in 2009 in Los Angeles and since has popped up more than 300 times in over 35 cities around the world. Each show draws as many as 3000 guests throughout the night.

WHEN:
Friday, September 28
8pm – 2am

WHERE:
The Opera House
735 Queen St. E.
Toronto, Ontario M4M 1H1

ABOUT TOM: Tom Kirlin, 40, left his movie career as a Hollywood cameraman to start Pancakes & Booze in 2009. Born in Tucson, Ariz., he’s a travel fiend who has visited over forty countries across every continent but Antarctica. At 6-foot-6, he’s a hell of a ringer in pick-up basketball games. Bug him at info@pancakesandbooze.com

There’s also this summary along with additional details from the announcement:

Toronto’s Premier Underground Art Show featuring:

  • 80+ Emerging Local Artists
  • Live Body Painting
  • Live Art
  • Live Music
  • FREE Pancake Bar
  • 21+ EVENT
  • 8pm – 2am
  • $10 – $13

Event info: https://www.facebook.com/events/390234974807730/

Tickets: https://www.brownpapertickets.com/event/3442689

The Opera House
735 Queen St. E.
Toronto, Ontario M4M 1H1

Wanna show some work?
Submit here: www.pancakesandbooze.com/submit

Check us out on

IG @pancakesandbooze

FB @pancakesandboozeartshow
Twitter @pancakesbooze

#pancakesandbooze

North Carolina: Art’s work in the age of biotechnology: Shaping our genetic futures

This too is from an August 12, 2018 Art/Sci Salon email,

This looks good!
Apply!

The NCSU [North Carolina State University] Libraries, NC State’s Genetic Engineering and Society (GES) Center, and the Gregg Museum of Art & Design have issued a public call for art for the upcoming exhibition Art’s Work in the Age of Biotechnology: Shaping our Genetic Futures.

Planned for fall 2019, the multi-site exhibition will be held simultaneously at the Gregg Museum of Art & Design and in the physical and digital display spaces of the NCSU Libraries–the Exhibit Gallery in the D. H. Hilll Library and the video walls in the James B. Hunt Jr. Library. Outdoor and/or greenhouse spaces are also available.

about

Art’s Work/Genetic Futures poses the question: How do artists and designers contribute materially, rhetorically, and conceptually to modern biotechnology? We are looking for contemporary work and project proposals that will engage viewers in examining how genomic sciences could shape the future of our society. Projects that question and challenge current biotechnology tropes, as well as projects that embrace the transformative potential of biotechnology and biomedicine, are welcome.

Guest curator Hannah Star Rogers will organize Art’s Work/Genetic Futures with a panel from the exhibition partners at NC State. Rogers has curated Making Science Visible: The Photography of Berenice Abbott, which received an exhibits prize from the British Society for the History of Science and resulted in an invited lecture at the Smithsonian Archives of American Art. She is past Director of Research and Collaboration forEmerge: Artists and Scientists Redesign the Future 2016 and served as Guest Bioart Curator for 2017.

This call is open to artists, scientists, designers, and makers at all career stages. Emerging artists, creators who are traditionally underrepresented in the arts and sciences, and artists working outside the U.S. are especially encouraged to apply.

Artists will receive an honorarium of $2,500 and three copies of the full-color catalog with essays by the curator and other contributors. Artists working in a collaborative team will share the honorarium.

The deadline for work and proposals is Monday, Oct. 1, 2018.

A shortlist will be announced Thursday, Nov. 15, 2018. Final notification of acceptance will be Tuesday, Jan. 15, 2019.

Full details about the exhibition, the call for art, and how to submit are available on the Art’s Work/Genetic Futures exhibition website at go.ncsu.edu/artswork.

Good luck!

Quantum Inkblot; An evening of physics, psychology, art and astronomy on July 12, 2018 in Vancouver (Canada)

A June 26, 2018 HR MacMillan Space Centre (HRMSC) press release, received via email, announces an upcoming art/sci event,

This July the H.R. MacMillan Space Centre and Voirelia: Dance, Psychology and Philosophy Hub will be co-hosting Quantum Inkblot, an interactive evening exploring quantum physics through the lenses of physics and psychology, art, and astronomy. The evening will incorporate talks by a physicist and a psychologist, visual artwork, and original contemporary dance performances.

The talks and artistic works will explore some of the questions about how psychology and physics can mirror, inspire, and influence one another. We will touch on topics related to relativity, uncertainty, and predictability of this world.

A dialogue-style talk will be led by physicist Dr. Jaymie Matthews and psychologist Dr. Alina Sotskova exploring the intersections of quantum physics and psychology. Dr. Matthews will be discussing the concept of wave-particle duality and the way it takes the assumption that one thing cannot be in two places at once and turns it on its head.

Dr. Sotskova will be talking about the dissonance in predicting the behaviour of groups vs. predicting the behaviour of individuals, giving pause to reflect on the existence of order at a macro level and chaos at the micro level.

The evening will also feature three original contemporary dance performances and a visual art and music presentation that were all inspired by themes in psychology and the intersection with physics.

There will be time between performances to enjoy a drink, take part in interactive art activities, watch physics demonstrations, and chat with physicists, artists, and psychologists. The evening will end with a question and answer period with all of the performers and speakers.

Here are logistics and additional details,

Quantum Inkblot will take place at the H.R. MacMillan Space Centre Thursday, July 12th.

This is a 19+ event.

6:30pm doors open, 7:00pm show starts in the Planetarium Star Theatre

$25 for tickets

Tickets available online through Eventbrite,[clicking on this link will give you a map to the location] in person, or by phone at 604.738.7827.

Find the Quantum Inkblot event on Facebook for sneak peeks at the art work being created, learn more about the process of collaboration between artists and scientists, and more!

The H.R. MacMillan Space Centre is a non-profit community resource that brings the wonders of space to Earth, while providing a personal sense of ongoing discovery. Through innovative programming, exhibits and activities, our goal is to inspire sustained interest in the fields of Earth science, space science and astronomy from a Canadian perspective.

Voirelia is a Vancouver-based Dance, Psychology, and Philosophy Hub. Its main purpose is to create original dance and art works inspired by ideas in psychology and philosophy. Voirelia also organizes talks, workshops, and events relevant to the intersection between dance, psychology, & philosophy, such as talks on philosophy of science. Our aim is “movement with meaning.”

BC Psychological Association has provided support for this event and BCPA representatives will be available to chat with the guests.

Voirelia provides a few more information and pictures on its Upcoming Projects webpage,

There will be several dance works presented during Quantum Inkblot. Here are the latest shots from one of the rehearsals, with physicists Dr. Jaymie Matthews and Dr. Ewan Hill joining us for a transdisciplinary open-rehearsal style session.

Photographs: Jason Kirkness. Dancers: Sophie Brassard, Michael Demski. Rehearsal direction/choreography: Alina Sotskova. [Not all the images have been included in this excerpt.]

 

We wanted to document our artistic and creative process as we put together this unique event. Below you will see examples of original art works and how artistic creation progresses. In the dance photographs below (by Jason Kirkness), we had a brainstorming session that included people with backgrounds in physics, psychology, dance, and theater. We spent about an hour talking about concepts from quantum physics that people often find “weird” – such as the concepts of waves, particles, wave-particle duality, and the uncertainty principle. We touched on how quantum physics influences our perception of science, the world, and ourselves. We discussed topics of identity and searching for meaning and why the quantum world is so different from what we see with our senses. Then we took our brainstorming to the dance studio. Here, using prompts suggested by physicists and her own knowledge as a psychologist and dancer, Alina Sotskova facilitated improvisational movement exploration. This yielded a great deal [sic] of ideas about parallels between physics and psychology, and we will use these ideas a spring board as we begin to develop specific dance works for the event. You can also check out short videos of the improvisational movement research session on our Facebook page, in the Videos section. [Not all the images have been included in this excerpt.]

The team who was part of the brainstorming session […] included: Andrew Elias (Graduate Student working in the field of quantum physics, UBC); Jason Kirkness (Co-lead for the Quantum Inkblot Event and; background: physics and computer science); Alina Sotskova (Co-lead for the Quantum Inkblot Event and; background: psychology and dance). Our dancers were: Angelo Moroni, Michael Demski, Carolyn Schmidt, Alejandra Miranda Caballero, Alina Sotskova.

The images below are samples of original art works by Andrew Short, one of Voirelia’s Core Consultants. Inspired by topics in quantum physics, psychology, and cosmology, Andrew is working on preparing a very special presentation especially for Quantum Inkblot. [There are more images at Voirelia.]

 

Interestingly, this does not seem to be a ‘sister’ event to Toronto’s ‘Out Of This World; Art inspired by all things astronomical’ exhibition and talks being held July 4 – 22, 2018 in honour of the Royal Astronomical Society of Canada’s (RASC) sesquicentennial (150th anniversary). There’s more about Toronto’s astronomical art/science event in my July 2, 2018 posting.

Curiosity collides with the quantum and with the Science Writers and Communicators of Canada in Vancouver (Canada)

There are a couple of events coming up in April and an opportunity to submit your work for inclusion in a Curiosity Collider event or two. There’s also a Science Writers and Communicators conference being held from April 12 – 15, 2018. All of this is happening in Vancouver, Canada.

Curiosity Collider events, etc.

Colliding with the Quantum

From a March 23, 2018 announcement (received via email) from CuriosityCollider.org,

MOA [Museum of Anthropology] Night Shift: Quantum Futures

In the quantum realm, what is observable and what is not? What happens when we mix art and science? 

Join us at UBC Museum of Anthropology on the evening of April 5 [2018] and immerse yourself in quantum physics through dance, spoken word, projection sculpture, virtual reality, and hands-on activities.

This event is curated by Curiosity Collider Art-Science Foundation with collaborations from UBC Physics & Astronomy and Stewart Blusson Quantum Matter Institute.

Let us know you are coming on Facebook | See list of participating artists/scientists

For anyone who needs directions, clicking on this UBC Museum of Anthropology link for Getting Here should help.

I wanted a few more details about the event and found them on Curiosity Collider’s Night Shift webpage,

Doors/Bar/Art & Science Activities 6 pm | Live Show 7:30 pm | Entry with museum admission ($10; free for UBC students & staff, Indigenous peoples, children under 6, and MOA Members)| Family Friendly

This event is curated by Curiosity Collider Creative Managing Director Char Hoyt.

The artwork gathered together for this event is a delightful blending of some of the most famous theories in Quantum Mechanics with both traditional and new artistic practices. When science is filtered through a creative expression it can both inspire and reveal new ways of seeing and understanding the concepts within. Our performers have crafted thoughtful experiences through dance, spoken word, sound, and light, that express the weirdness of the quantum realm and how it is reflected in our daily lives. We have also worked closely with scientists to develop hands-on activities that embody the same principles to create experiences that engage your creativity in understanding the quantum world. We encourage you to interact with the artists and scientists and let their work guide you through the quantum realm.

Participating artists and scientists

Most of these folks are associated with the Quantum Matter Institute.

Call for submissions

From a March 23, 2018 announcement (received via email) from CuriosityCollider.org,

Call for Submissions:
Women in STEM Exhibition

Interstitial: Science Innovations by Canadian Women is a two-week exhibition (June 1-14) and events showcasing work by female artists featuring women in STEM. We are looking for one more 2D artist/illustrator to join the exhibition and will accept existing work. Deadline April 6. To submit, visit our website.

This exhibition is funded by the Westcoast Women in Engineering, Science and Technology (WWEST) and eng-cite.

#Sciart & #Scicomm at Science World on April 12, 2018 (a Science Writers and Communicators of Canada [SWCC] reception)

From a March 23, 2018 announcement (received via email) from CuriosityCollider.org,

#Sciart & #Scicomm at Science World

On April 12, Curiosity Collider is bringing art+science to the Science Writers and Communications of Canada Annual Conference here in Vancouver. The public evening event will include performances and activities by Curiosity Collider, Science Slam, Beaker Head (Alberta) [sic], and SFU (Simon Fraser University) Faculty of Applied Science. We will also be hosting a silent auction to showcase local #sciart and support future art+science project, including our annual exhibition SPARK!

Get your tickets now! | Let us know you are coming on Facebook

I found more information about this event at something called allevents.in/vancouver,

SciComm Social with SWCC and STAN

Science Writers and Communicators of Canada (SWCC) and Science Technology Awareness Network (STAN) are hosting their annual conferences in Vancouver in April. This joint reception event featuring #scicomm and #sciart is free for conference delegates and also open to the public … . [emphasis mine]

Friends, family, and fans of science communication & communicators welcome!

This evening event will include performances and activities from:
* Beakerhead – Power Point Karaoke, hosted by Banff SciComm/Beakerhead alumni: A deck of slides is provided. Brave participants, who have never seen the slides before, improvise the talk. Hilarity ensues, egged on by an enthusiastic audience.
* Curiosity Collider – #sciart silent auction, stage performances, and art installation
* SFU Applied Sciences – interactive technology exhibits
* Science Slam Canada – Whether it’s a talk, a poem, a song, a dance, or something completely unexpected, the possibilities are endless. Our only two rules? Five minute slams, and no slideshows allowed!

Get your tickets – available until April 10! This is a 19+ event. Performances starting at 7:30, doors at 7 pm.

Weirdly, no mention is made of the cost. Tickets are $25. for anyone who’s not attending the conference and you can register for and purchase your ticket here. As for location, this event is being held at Science World at Telus World of Science (known locally as Science World), here’s where you find directions for how to get to Science World.

Science Writers and Communicators Conference in Vancouver from April 12 – 15, 2018

Before getting to the costs here a couple of peeks at the programme. First, there’s a March 25, 2018 posting on the SWCC blog by Ashley EM Miller about one of the conference sessions,

Art can be a way to engage the public with science through the the simple fact that novelty sparks curiosity. Artists in the emerging field of sci-art utilize science concepts, methods, principles and information within their practice. Their art, along with the work of science illustrators, can facilitate a deeper emotional connection to science, particularly in those who don’t regularly pay attention or feel welcome.

However, using artwork in science communication is not as simple as inserting a picture into a body of text and referencing the artist in MLA style.

For those coming from the sciences, citing your sources, as laborious as that may be, is a given. While that is fine for incorporating  information, that isn’t always adequate for artwork. In the art world, artists know how to ask other artists to use their work. If a scientist or science communicator does not have an “in” with the art community, they may not know where to find legal information about using art.


Anyone interested in using artwork in their science communication practice, should attend the upcoming SWCC conference’s professional development session “On Copyright, Ethics and Attribution: Interdisciplinary Collaborations Between Artists and Scientists”. The panel discussion will be moderated by Theresa Liao of Curiosity Collider and Sarah Louadi of Voirelia, both of whom are intimately familiar with combining art and science in their respective organizations. Sarah and Theresa will lead a much-needed conversation about the benefits and best practices of partnerships between artists and science communicators.


The session boasts a well-rounded panel. Attendees will gain insights on aspects of the art world with panelists Kate Campbell, a science illustrator, and Steven J. Barnes, a psychologist and artist. Legal and ethical considerations will be provided by Lawrence Chan, an intellectual property lawyer, and April Britski, the National Executive Director of Canadian Artists’ Representation/Le Front des artistes canadiens (CARFAC). For those unfamiliar, CARFAC is a federal organization that acts as a voice for visual artists in Canada and outlines minimum fee guidelines among other things.

Science communicators and bloggers will certainly benefit from the session, particularly early-career freelancers. When working independently, there are no organizational policies and procedures in place for you to follow. It means that you have to check everything yourself, and this session will give you a crash course of what to look for in artist collaborations, what to ask and how to ask it. Even researchers will benefit from the discussion, by learning about the opportunities for working with science illustrators and about what to expect.


On Copyright, Ethics and Attribution: Interdisciplinary Collaborations Between Artists and Scientists”. will take place at 3:15 pm on Saturday April 14th as part of the conference’s concurrent Professional Development sessions. …

There’s a programme schedule for the 2018 conference here and it includes both an “At a glance’ version and a more fulsome description of the various sessions such as these,

THURSDAY APRIL 12

Act your Science – Interactive Improvisation Training

10:00 am – 12:00 pm Innovation Lab

Come and share a taste of a communication program developed by Jeff Dunn, in collaboration with SWCC, the Loose Moose Theatre in Calgary and the University of Calgary. The goal of this presentation is to provide a taste of how improvisation can be used to improve communication skills in science fields. This hands-on exercise will help participants build capacity to communicate science to various audiences by learning how to fail gracefully in public (to help reduce presentation anxiety), how to connect with your audience and how to recognize and use status in personal interactions.

The full program is 10hrs of training, in this shorter session, we will sample the program in a fun interactive environment. Be prepared to release your inner thespian. Space is limited to 20 people

Jeff Dunn has been a research scientist in brain and imaging for over 30 years. He has a strong interest in mentoring science trainees to broaden their career skills and has recently been developing programs to improve science communication. One class, gaining traction, is “Act your Science”, a custom designed course using improvisation to improving science communication skills for science trainees. He is an alumni of the Banff Science Communication program where he first experienced improvisation training for science. He has held a Canada Research Chair and has Directed the Experimental Imaging Centre at the University of Calgary since 2004. He has over 150 science publications in diverse journals ranging from Polar Biology to the Journal of Neurotrauma. He has supervised scores of graduate students and taught on subjects including MRI, optical imaging and brain physiology at altitude. His imaging research currently includes multiple sclerosis, brain cancer and concussion.

Video Booth: How I SciComm – go ahead and tell all, we want to know! 

 Available 10:am – 2:30pm: Exploration Lab

A camera team will be on hand to help you record and upload your 1 minute video about who you are, and how you do your science communications. Here are some questions for you to think about:

1. Who are you?

2. How do you do your science communications?

3. What’s your favourite science trivia? What’s something cool you learned when researching a storyWhat’s your favourite jargon? What’s a word you had to memorizing pronunciation or spelling for a story

A Community of Innovators: 50 Years of TRIUMF

2:30 -3:30 pm  Science Theatre

 

Ask TRIUMF’s spirited founders and emeriti about the humble beginnings of Canada’s particle accelerator centre and you will invariably hear: “This used to be just a big pile of dirt.” You could imagine TRIUMF’s founding members five decades ago standing at the edge of the empty lot nestled between the forest and the sea, contemplating possibilities. But not even TRIUMF’s founders could have imagined the twists and turns of the lab’s 50-year journey, nor the impact that the lab would have on the people of Canada and the world.

Today, on that same 12.8-acre plot of land, TRIUMF houses world-leading research and technology, and fuels Canada’s collective imagination for the future of particle and nuclear physics and accelerator science. Join TRIUMF’s Director Jonathan Bagger and colleagues for an exploration of TRIUMF’s origins, impacts, and possibilities – a story of collaboration that over five decades celebrates a multifaceted community and growing family of 20 Canadian member universities and partners from around the world. www.triumf50.com  @TRIUMFlab

FRIDAY, APRIL 13 

Frontiers in SciComm Policy & Practice

Canada 2067 – Building a national vision for STEM learning

10:30 Room 1900

Canada 2067 is an ambitious initiative to develop a national vision and goals for youth learning in science, technology, engineering and math (STEM). Significant and scalable changes in education can be achieved by aligning efforts towards shared goals that support all children and youth in Canada.  A draft framework has been developed that builds on research into global policy, broad-based public input, five youth summits, consultation with millennials and a national leadership conference. It calls for action by diverse stakeholders including students, educators, parents, community organizations, industry and all levels of governments.  In this workshop, participants will learn about the initiative and discuss the inherent challenges of catalyzing education change in Canada. Participants will also review the framework and provide feedback that will be incorporated into the final version of the Canada 2067 framework. Input into the design of phase 2 will also be encouraged.

Bonnie Schmidt, C.M., Ph.D.

Founder and President, Let’s Talk Science

Dr. Bonnie Schmidt is the founder and president of Let’s Talk Science, a national charitable organization that helps Canadian youth prepare for future careers and citizenship roles by supporting their engagement in science, technology, engineering and math (STEM). Annually, Let’s Talk Science is accessed by more than 40% of schools in over 1,700 communities, impacting nearly 1 million youth. More than 3,500 volunteers at 45 post-secondary sites form our world-class outreach network. Bonnie currently serves as Chair of the National Leadership Taskforce on Education & Skills for the Information and Communications Technology Council (ICTC) and is on the Board of Governors of the University of Ontario Institute of Technology (UOIT). She was named a Member of the Order of Canada in 2015 and has received an Honorary Doctorate (Ryerson University), the Purvis Memorial Award (Chemical Institute of Canada), Community Service Award (Life Sciences Ontario), and a Queen’s Diamond Jubilee Award. @BMSchmidt

Infographics: Worth a Thousand Words with Kate Broadly and Sonya Odsen

1:15 Room 1520

Infographics have become a popular way to present results to non-specialist audiences, and they are a very effective tool for sharing science on social platforms. Infographics are more likely to be shared online, where they increase engagement with scientific content on platforms like Twitter.

No art skills? No problem! This session will guide you through the process of creating your own infographic, from crafting your story to telling that story visually, and will include strategies to design effective visuals without having to draw (unless you want to!). Topics will include developing your key messages, making your visuals functional rather than decorative, tips for giving your visuals a professional edge, and the best software options for each artistic skill level. Our goal is to empower you to create a visually-pleasing infographic regardless of your art or drawing experience. At the end of this active session, you will have a draft of your own unique infographic ready to be made digital.

The skills you develop during this session will be readily transferable to other visual media, such as talks, posters, or even creating visuals for blog posts.

Kate Broadley

Sonya Odsen

Kate Broadley and Sonya Odsen are Science Communicators with Fuse Consulting. Located in Edmonton, Alberta, Fuse is dedicated to communicating cutting-edge research to different audiences in creative and innovative ways. Their ultimate goal is to bring knowledge to life and empower audiences to apply that knowledge in policy, conservation, research, and their day-to-day lives. Every day, Kate and Sonya tackle complex topics and transform them for specific audiences through writing and design. Infographics are one of their favourite tools for conveying information in fun and accessible ways. Their past and current design projects include interpretive signage for Nature Conservancy Canada, twitter-optimized visual abstracts for the Applied Conservation Ecology lab at the University of Alberta, and a series of science-inspired holiday cards. You can see examples of their work at http://www.fuseconsulting.ca/see-our-work/. Kate and Sonya are also ecologists by training, each holding an M.Sc. from the University of Alberta.

Should this excite your interest,  get going as registration ends March 29, 2018. Here are the rates and the registration link is at the end,

Everyone is Welcome

RATES

Early Bird Registration

SWCC Members: $300

Non-members: $400

Regular Registration 

SWCC Members: $400

  Non-members: $500

Student Rates

SWCC student members: $150

Non-member students: $200

Beakerhead Course: $500

(includes day rate + course fee)

Day Rate: $150

Victoria Half Day Rate: $75

Snorkel Safari: snorkeler $120

Snorkel Safari: ride along $90

Social Evening, April 12

  TELUS Science World, 7:00-10:00pm additional single event tickets: $25.00 (limited)

DATES

EARLY BIRD REGISTRATION OPENS: MONDAY, FEBRUARY 5, 2018

EARLY BIRD REGISTRATION CLOSES: FRIDAY MARCH 9, 2018

REGISTRATION FINAL DEADLINE: THURSDAY MARCH 29, 2018

Conference Dates

April 12, TELUS Science World with STAN

April 13 & 14, SFU Harbour Centre

April 15, Vancouver tours & Victoria day Royal BC Museum

Travel and Accommodation information is available here

Register Here

Have fun!

BIODESIGN : Nature + Science + Creativity call for artists and a job posting (Rhode Island School of Design)

h/t @raymondsbrain (Raymond Nakamura) for this item from the Rhode Island School of Design (RISD) BIODESIGN: Nature + Science + Creativity call for proposals webpage,

OPEN CALL for Proposals

Exhibition: Biodesign : From Inspiration to Integration

Venue: Rhode Island School of Design (RISD)

Submit your Biodesign or Bioart projects or ideas for programs and workshops

Funding available for production and transportation

Deadline for proposals: March 15, 2018

Curated by: William Myers & The Nature Lab @ RISD

Exhibition Dates: August 25 through September 27, 2018

Click [here] to download guidelines

Summary: The exhibition will showcase recent examples of design and art that help reform our relationship with nature, moving it from a destructive to a more integrated, mutually beneficial model. Major themes will include collaboration and co-creativity, presenting emerging best practices for working with living materials and with experts across fields. The presentation of approximately 20 projects will accompany programming including workshops, lectures, and panel discussions. This exhibition will welcome audiences curious about new experiments in designing, manufacturing and building that prioritize biodiversity protection and highlight new artistic practices that integrate biological processes or reflect on advances in the life sciences.

I followed the link to the guidelines and found some additional information,

The Nature Lab at RISD is pleased to announce Biodesign: From Inspiration to Integration, an exhibition curated by William Myers to mark the closing of our 80th anniversary celebrations. The exhibition will open in Spring 2018 and showcase recent examples of design and art that help reform our relationship with nature, moving it from a destructive to a more integrated, mutually beneficial model.

Please submit a 1–4 page summary of the work you propose for the exhibition, including
3 supporting images, via email. Also attach a current CV to your message and be sure to include your website or portfolio if applicable. Include any estimates of production, shipping or other related expenses for the project. Please keep the e-mail size under
10MB and include “RISD Exhibition Proposal” and your last name in the subject line. This call is open to everyone. Applicants can expect a response before the end of April [2018].

There is also a job, which is paid, part-time, and remote,

We are seeking a Curatorial Assistant to develop the exhibition. It is a paid, part-time post that can be located anywhere. Deadline to apply is March 2nd [2018]. Description here.

A SciArt Gallery @ Science Rendezvous call for artists and a SciFi and Fantasy screenplay contest and

I’ve got two ‘creativity’ opportunities, one for people working on an art/sci (sciart) project and another for people with scripts,

SciArt Gallery @ Science Rendezvous

This notice arrived in a January 31, 2018 email from the ArtSci Salon people in Toronto (Ontario, Canada),

Science Rendezvous is a free Canada‐wide outreach festival that spurs interest in scientific research among the general public and last year at U of T, we attracted over 30,000 guests! This year we are hosting our first science-inspired art gallery called the SciArt Gallery! We are actively recruiting artists for the gallery to display their science-inspired works! Painting, design, music, dance, theatre, textiles, ceramics: We welcome all artists to apply!

To apply and for more information, please visit: http://bit.ly/SciArtGallery2018

The open call deadline is Friday, February 23rd, 2018 at 11:59pm!

To learn more about Science Rendezvous and this year’s festival on Saturday, May 12th, please visit www.ScienceRendezvousUofT.ca.

So you know what you might be getting into, the About Science Rendezvous webpage has this to say about what the organization does and about its origins,

We work with Canada’s top research institutes to present a coast-to-coast open house and festival that is FREE for everyone. With over 300 events across 30 cities and 1000’s of mind-blowing activities, Science Rendezvous is Canada’s largest celebration of the amazing feats of science and engineering happening right here at home.

In 2017, more than 210,000 attendees participated in our unique brand of hands-on science, a new landmark for such events in Canada. Science Rendezvous is the only organization that generates this level of public engagement with science, and direct face-to-face involvement with those at the very frontiers of innovation.

This SATURDAY, MAY 12th 2018 [emphasis mine] over 6,000 of Canada’s greatest innovators, researchers, engineers, and scientists from 125 partner organizations will open their doors and close city streets to present exciting demonstrations, hands-on activities, and explosive experiments. From the physics of rock and roll to the chemistry of ice-cream, Science Rendezvous has something for everyone!

History

Science Rendezvous began as a joint program between the University of Toronto, Ryerson University, York University and the University of Ontario Institute of Technology (UOIT) in 2008. These founding partners saw the need to work together in order to launch an event of great enough scale and exciting content to engage the public in the vast wonders of science and engineering. Since that time, Science Rendezvous has grown to include 40 of Canada’s top research institutions and over 85 community partnerships across 30 cities in 10 provinces and 2 territories. Today, it is a marquee event and signature partner of Science Odyssey [Note: This is a government of Canada annual national “celebration of science, technology, engineering and mathematics, featuring fun and inspiring experiences in museums, research centres, laboratories and classrooms from coast to coast” which will run from May 11 – 20, 2018 this year], and is the single largest science festival in Canada.

Science Rendezvous is a science outreach pioneer in Canada. Offering direct engagement with 6,000 of Canada’s top researchers and scientists at 300 simultaneous events and 1000’s of hands-on experiments for the public to try themselves.

The Science Rendezvous head office acts as an umbrella organization that coordinates the efforts of all participating institutions, reinvents public engagement with science through festival programming, and offers direction for event organizers all while promoting both the festival and Canadian science on a national level.

To be clear, the call for sciart projects is from the physics department at the University of Toronto (U of T) and the deadline is February 23, 2018. I went to the U of T Science Rendezvous SciArt Gallery artist application page and found more details about the call,

The theme for SR 2018 is “Full S.T.E.A.M. Ahead!” – We’re placing an emphasis on the Art in S.T.E.M. [science, technology, engineering, and mathematics] this year and hosting our first and hopefully annual SciArt Gallery! We want to create a gallery full of science-inspired art and showcase the talent of our local Toronto artists! We hope that artists will be able to share their enthusiasm and teach visitors about how science inspired you to create and the science behind the art!

Artists will be permitted to sell their wares and will be provided with tents, chairs, volunteers, t-shirts, and lunch if accepted to the gallery. SR2018 is currently accepting applications for its SciArt Gallery taking place on Saturday, May 12, 2018 from 11am to 5pm.

There will be a $20 table deposit fee that will be refunded upon your attendance at SR. SR hopes to showcase science-inspired works of art and host workshops to allow artists to inspire kids and adults about their art medium.

*** Applications will close on Friday, February 23rd, 2018 at 11:59pm! ***

If you have any questions or concerns, please do not hesitate to contact us at uoftsr.sciartgallery@gmail.com

For more information and to keep up-to-date about the SciArt Gallery, please visit our:

Website: http://www.sciencerendezvousuoft.ca/
Facebook: https://www.facebook.com/UofTSR/

The name and photo associated with your Google account will be recorded when you upload files and submit this form.

I don’t know if you noticed but the application page specifies Toronto artists while the email did not. You may want to contact the organizers for more details. At a guess, they don’t want to fund any trips or accommodation for out-of-town artists but if you’re willing to self-fund they’ll consider your application.

One final thing worth mentioning, there may be opportunities in your home community. So, it may be worthwhile to check out the Science Rendezvous website.

SciFi and fantasy screenplay contest

I got this January 31, 2018 withoutabox.com announcement via email,

… the 4th Annual ScreenCraft Sci-Fi & Fantasy Screenplay Contest, an out of this world screenplay competition set to discover talented writers. The 2018 contest judges are Steven Douglas-Craig, Development at Sony Pictures, the studio behind Passengers, Ghostbusters, Men In Black, Resident Evil, and Spider-Man; Jonathan Wu, Development Executive at 20th Century Fox, the studio behind Avatar, X-Men, Another Earth, Rise Of The Planet Of The Apes, and Prometheus ; and Michael Doven, CEO of United Pictures, producer of such celebrated movies as Mission: Impossible, Vanilla Sky, Minority Report, and The Last Samurai.

The Grand Prize winner will receive a $1,000 USD cash award and personal introductions to producers, managers, agents and studio executives. Additionally, the top finalists will be circulated to ScreenCraft’s vetted network of over 60 producers, studio executives, managers and agents. Whether you’re writing a contained science fiction drama or an epic fantasy saga, ScreenCraft wants to read your sci-fi or fantasy feature film screenplay. Great science fiction explores the human condition against the backdrop of a heightened imagined world, impacted by technology and human creativity and imagination.

Past ScreenCraft winners have optioned their projects and signed with top representatives at top Hollywood companies including WME, CAA, 3Arts Entertainment, Anonymous Content, Paradigm Talent Agency, ICM, Bellevue Productions Zero Gravity Management, Kaplan/Perrone and many more.

UPCOMING DEADLINE
February 9, 2018 – Earlybird Deadline [March 30,2018 final deadline]

View submission details

MISSION AND OBJECTIVE
ScreenCraft’s screenwriting contests are dedicated to discovering talented screenwriters and connecting them with producers, agents and managers.

MORE ABOUT THE FESTIVAL
ScreenCraft runs a suite of screenwriting competitions that have a long history of getting writers represented and working. The secret is that ScreenCraft actually determines the winners with judges who work in the particular genre or space – real industry executives (not just readers). The winners get actual meetings with actual executives, so that a relationship forms beyond just a great script.

I checked for more details and found this (from the withoutabox.com 4th Annual ScreenCraft Sci-Fi & Fantasy Screenplay Contest Submission webpage),

RULES:
Submissions are accepted via electronic submission only, between January 10, 2018 and March 30, 2018.
Entry fee for each feature film screenplay is $49 until the early deadline on February 9, 2018, then $69 until the final deadline on March 30, 2018.
Optional feedback from a professional reader may be requested at the time of entry. Requests for feedback after an entry is submitted will not be accepted.
Screenplays must be a minimum of 75 pages and a maximum of 150 pages.
There is no limit to the number of projects you may submit.
Entries must be received on or before the deadline dates by 11:59PM Pacific Time, and submission fee payment must be made in full at time of the submission. All entry fees are non-refundable.
All submitted material must be original, and all rights must be wholly owned by the writer(s).
Material must be submitted by the writer. Material written by writing teams must be submitted by one of the writers, with consent of the other(s). All writers must be credited on title page.
If a writing team is chosen as a winner, prizes will be given to the person who submits the project. Each team is responsible for dividing or sharing the prize money.
Substitutions of either corrected pages or new drafts of the entered material will be allowed for a limited time with a $5 reentry fee through Coverfly. Please proofread your script carefully before submitting.
It is recommended that original material be registered with the WGA or The Library of Congress before submitting to any competition, however we do not require registration.
Contact info may be included on the cover page of the screenplay, however it is not required.
All ownership and rights to the scripts submitted to this contest remains with the original rights holders.

ELIGIBILITY:
All writers at least 18 years of age are eligible. However, a writer who has earned more than $50,000 (or equivalent currency) from professional writing services for film or TV in the preceding year is not. (Contest winnings not included.)
All persons from anywhere in the world are eligible; however the material submitted must be in English (occasional dialogue in other languages is acceptable, if subtitle translation is provided).
All material submitted to other competitions or contests are eligible for this contest.
There are no requirements as to when the material was written.
Screenplay and intellectual property must be wholly owned and submitted by the writer(s).
Material should be submitted in standard screenplay format, font, spacing and margin.
We have no preferences regarding title page content. Title and name of writer would suffice.
Entries for this competition are managed on the submission platform Coverfly.
Adaptations are ineligible unless the underlying rights are owned by the writer or the work is in the public domain.
Feature screenplays longer than 150 pages will not be eligible.
All material must be submitted electronically as a PDF or it will not be eligible.

You can find out more about ScreenCraft here.

To everyone: good luck!

Café Scientifique Vancouver talk on January 30, 2018 and a couple of February 2018 art/sci events in Toronto

Vancouver

This could be a first for Café Scientifique Vancouver. From a January 28, 2018 Café Scientifique Vancouver announcement (received via email)

This is a reminder that our next café with biotech entrepreneur Dr.Andrew Tait (TUESDAY, JANUARY 30TH [2018] at 7:30PM) in the back room of YAGGER'S DOWNTOWN (433 W Pender).

COMBINING TRADITIONAL NATURAL MEDICINES WITH SCIENTIFIC RESEARCH: UNVEILING THE POTENTIAL OF THE MANDARIN ORANGE PEEL

The orange peel is something most of us may think of as a throw-away compost item, but it is so much more. Travel back in time 9,000 years to China, where orange peel was found in the first fermented alcoholic beverage, and return to today, where mandarin orange peel remains one of China’s top selling herbs that promotes digestion. Now meet Tait Laboratories Inc., a company that was founded based on one chemistry Ph.D. student’s idea, that mandarin orange peel has the potential to reverse incurable neurodegenerative diseases like multiple sclerosis. You will learn about the company’s journey through a scientific lens, from its early days to the present, having developed a mandarin orange peel product sold across Canada in over 1,000 stores including 400 Rexall pharmacies. You will leave with a basic understanding of how herbal products like the company’s mandarin orange peel-based product are developed and brought to market in Canada, and about the science that is required to substantiate health claims on this and other exciting new botanical products.

Bio:

Dr. Andrew Tait is the founder of Tait Laboratories Inc., a company devoted to developing natural medicines from agricultural bi-products. After a B.Sc. in Biochemistry and M.Sc. in Chemistry from Concordia University (Montreal), he completed a Ph.D. in Chemistry at the
University of British Columbia [UBC].

Inspired by his thesis work on multiple sclerosis, he subsequently identified Traditional Chinese Medicines as having potential to treat a wide range of chronic diseases; he founded the company while finishing his graduate studies.

In 2012, he was invited to Ottawa to be awarded the NSERC [{Canada} Natural Sciences and Engineering Research Council] Innovation Challenge Award, for successfully translating his Ph.D. research to an entrepreneurial venture. In 2014, he was awarded the BC Food Processors Association “Rising Star” award.

Dr. Tait is a regularly invited speaker on the topics of entrepreneurship and the science supporting natural health products; he was keynote speaker in 2012 at the Annual Symposium of the Boucher Institute of Naturopathic Medicine (Vancouver) and in 2016 at the
Functional Foods and Natural Health Products Graduate Research Symposium (Winnipeg).

Supported by the Futurpreneur Canada, the Bank of Development of Canada, the UBC’s Entrepreneurship@UBC program, and the NSERC  and NRC  [{Canada} National Research Council] Industry Research Assistance Program (IRAP), he works with industrial and academic researchers developing safe, affordable, and clinically proven medicines. He successfully launched MS+ Mandarin Skin PlusÒ, a patent-pending digestive product now on shelf in over 1000 pharmacies and health food stores across Canada, including 400 Rexall pharmacies.

Dr. Tait mentors young companies as an Entrepreneur in Residence at both SFU [Simon Fraser University] Coast Capital Savings Venture Connection and also the Health Tech Innovation Hub and he also volunteers his time to mentor students of the Student Biotechnology Network.

Lest it be forgotten, many drugs and therapeutic agents are based on natural remedies; a fact often ignored in the discussion about drugs and natural remedies. In any event, I am surprised this talk is being hosted by Café Scientifique Vancouver which has tended to more ‘traditional’ (i.e., university academic) presentations without any hint of ‘alternative’ or ‘entrepreneurial’ aspects. I wonder if this is the harbinger of new things to come from the Café Scientifique Vancouver community.

Meanwhile, interested parties can find out more about Tait Laboratories on their company website. They are selling one product at this time (from the MS+ [Mandarin Skin Plus] product webpage,

MS+™ (Mandarin Skin Plus) is a revolutionary natural health product that aids with digestion and promotes gastrointestinal health. It is a patent-pending proprietary extract based on dry-aged mandarin orange peel, an ancient Traditional Chinese Medicine. This remedy has been safely used for centuries to relieve bloating, indigestion, diarrhea, nausea, upset stomach, cough with phlegm. Experience ULTIMATE DIGESTIVE RELIEF and top gastrointestinal health for only about a dollar a day!

Directions: take one capsule twice a day, up to six capsules per day. Swallow capsule directly OR dissolve powder in water.
60 vegan capsules for ~ 1 month supply

I would have liked to have seen a list of research papers and discussion of human clinical trials regarding their ‘digestive’ product. Will Tait be discussing his research and results into what seems to be a new direction (i.e., the use of mandarin skin peel-derived therapeutics for neurodegenerative diseases)?

I don’t think I’m going to make it to the talk but should anyone who attends care to answer the question, please feel free to add a comment.

ArtSci Salon in Toronto

2018 is proving to be an active year for the ArtSci Salon folks in Toronto. They’ve just finished hosting a January 24-25, 2018 workshop and January 26, 2018 panel discussion on the gene-editing tool CRISPR/CAS9 (see my January 10, 2018 posting for a description).

Now they’ve announced another workshop and panel discussion on successive nights in February, the topic being: cells. From a January 29, 2018 ArtSci Salon announcement (received via email), Note: The panel discussion is listed first, then the workshop, then the artists’ biographies,

FROM CELL TO CANVAS: CREATIVE EXPLORATIONS OF THE MICROSCOPIC [panel discussion]

From the complex forms of the cell to the colonies created by the microbiota; from the undetectable chemical reactions activated by enzymes and natural processes to the environmental information captured through data visualization, the five local and international artists presenting tonight have developed a range of very diverse practices all inspired by the invisible, the undetectable and the microscopic.

We invite you to an evening of artist talks and discussion on the creative process of exploring the microscopic and using living organisms in art, on its potentials and implication for science and its popular dissemination, as well as on its ethics.

WITH:
Robyn Crouch
Mellissa Fisher
JULIA KROLIK
SHAVON MADDEN
TOSCA TERAN

FRIDAY, FEB 9, 2018
6:00-8:00 PM
THE FIELDS INSTITUTE
222 COLLEGE STREET,
RM 230

[Go to this page for access to registration]

FROM CELL TO CANVAS: CREATIVE EXPLORATIONS OF THE MICROSCOPIC [workshop]

THE EVENT WILL BE FOLLOWED BY A WORKSHOP BY: MELLISSA FISHER, SHAVON MADDEN AND JULIA KROLIK
FEB. 10, 2018
11:00AM-5:00PM
AT HACKLAB,
1266 Queen St West

[Go to this page for access to registration]

Workshop:

Design My Microbiome

Artist Mellissa Fisher invites participants to mould parts of her body in agar to create their own microbial version of her, alongside producing their own microbial portrait with painting techniques.

Cooking with the Invasive

Artist Shavon Madden invites participants to discuss invasive species like garlic mustard and cook invasive species whilst exploring, do species which we define and brand as invasive simply have no benefits?

Intoduction to Biological Staining

Artist & Scientist Julia Krolik invites participants to learn about 3 different types of biological staining and have a chance to try staining procedures.

BIOS:

ROBYN CROUCH
The symbolic imagery that comes through Robyn’s work invites one’s gaze inward to the cellular realms. There, one discovers playful depictions of chemical processes; the unseen lattice upon which our macro­cosmic world is constructed. Technological advancements create windows into this molecular realm, and human consciousness acts as the interface between the seen and the unseen worlds. In her functional ceramic work, the influence of Chinese and Japanese tea ceremony encourages contem­plation and appreciation of a quiet
moment. The viewer-participant can lose their train of thought while meandering through geometry and biota, con­nected by strands of double-helical DNA. A flash of recognition, a momentary mirror.

MELLISSA FISHER
Mellissa Fisher is a British Bio Artist based in Kent. Her practice explores the invisible world on our skin by using living organisms and by creating sculptures made with agar to show the public what the surface of our skin really looks like. She is best known for her work with bacteria and works extensively with collaborators in microbiology and immunology. She has exhibited an installation _ “Microbial Me”_with Professor Mark Clements and Dr Richard Harvey at The Eden Project for their permanent exhibition _“The Invisible You: The Human
Microbiome”._The installation included a living portrait in bacteria of the artists face as well as a time-lapse film of the sculpture growing.

JULIA KROLIK
Julia Krolik is a creative director, entrepreneur, scientist and award-winning artist. Her diverse background enables a rare cross-disciplinary empathy, and she continuously advocates for both art and science through several initiatives. Julia is the founder of Art the Science, a non-profit organization dedicated to facilitating artist residencies in scientific research laboratories to foster Canadian science-art culture and expand scientific knowledge communication to benefit the public. Through her consulting agency Pixels and Plans, Julia works with private and public organizations, helping them with strategy, data visualization and knowledge mobilization, often utilizing creative technology and skills-transfer workshops.

SHAVON MADDEN
Shavon Madden is a Brampton based artist, specializing in sculptural, performance and instillation based work exploring the social injustices inflicted on the environment and its creatures. Her work focuses on challenging social-environmental and political ethics, through the embodied experience and feelings of self. She graduated from the University of Toronto Specializing in Art and Art History, along with studies in Environmental Science and will be on her way to Edinburgh for her MFA. Shavon has had works shown at Shelly Peterson, the Burlington Art Gallery and the Art Gallery of Mississauga, among many others. Website: www.greenheartartistry.com [4]

TOSCA TERAN
Working with metal for over 30+ years, Tosca was introduced to glass as an artistic medium in 2004. Through developing bodies of work incorporating metal + glass Tosca has been awarded scholarships at The Corning Museum of Glass, Pilchuck Glass School and The Penland school of Crafts. Her work has been featured at SOFA New York, Culture Canada,
Metalsmith Magazine, The Toronto Design Exchange, and the Memphis Metal Museum. She has been awarded residencies at Gullkistan, Nes, and the Ayatana Research Program. A long-term guest artist instructor at the Ontario Science Centre, Tosca continues to explore materials, code, BioArt, SciArt and teach Metal + Glass courses out of her studio in Toronto.

It seems that these February events and the two events with Marta de Menezes are part of the FACTT (transdisciplinary and transnational festival of art and science) Toronto, from the FACTT Toronto webpage,

FACTT Toronto – Festival of Art & Science posted in: blog, events

The Arte Institute, in partnership with Cultivamos Cultura and ArtSi Salon, has the pleasure to announce FACTT – Festival of Art & Science in Toronto.

The Festival took place in Lisbon, New York, Mexico, Berlin and will continue in Toronto.
Exhibition: The Cabinet Project/ Art Sci Salon / FACTT

Artists:

Andrew Carnie
Elaine Whittaker
Erich Berger
Joana Ricou
Ken Rinaldo
Laura Beloff and Maria Antonia Gonzalez Valerio
Marta de Menezes and Luís Graça
Pedro Cruz

Dates: Jan 26- feb 15 [2018 {sic}]

Where: Meet us on Jan 26 [2018] in the Lobby of the Physics Department, 255 Huron Street
University of Toronto
When: 4:45 PM

You may want to keep an eye on the ArtSci Salon website although I find their posting schedule a bit erratic. Sometimes, I get email notices for events that aren’t yet listed on their website.

Why don’t you CRISPR yourself?

It must have been quite the conference. Josiah Zayner plunged a needle into himself and claimed to have changed his DNA (deoxyribonucleic acid) while giving his talk. (*Segue: There is some Canadian content if you keep reading.*) From an Oct. 10, 2017 article by Adele Peters for Fast Company (Note: A link has been removed),

“What we’ve got here is some DNA, and this is a syringe,” Josiah Zayner tells a room full of synthetic biologists and other researchers. He fills the needle and plunges it into his skin. “This will modify my muscle genes and give me bigger muscles.”

Zayner, a biohacker–basically meaning he experiments with biology in a DIY lab rather than a traditional one–was giving a talk called “A Step-by-Step Guide to Genetically Modifying Yourself With CRISPR” at the SynBioBeta conference in San Francisco, where other presentations featured academics in suits and the young CEOs of typical biotech startups. Unlike the others, he started his workshop by handing out shots of scotch and a booklet explaining the basics of DIY [do-it-yourwelf] genome engineering.

If you want to genetically modify yourself, it turns out, it’s not necessarily complicated. As he offered samples in small baggies to the crowd, Zayner explained that it took him about five minutes to make the DNA that he brought to the presentation. The vial held Cas9, an enzyme that snips DNA at a particular location targeted by guide RNA, in the gene-editing system known as CRISPR. In this case, it was designed to knock out the myostatin gene, which produces a hormone that limits muscle growth and lets muscles atrophy. In a study in China, dogs with the edited gene had double the muscle mass of normal dogs. If anyone in the audience wanted to try it, they could take a vial home and inject it later. Even rubbing it on skin, Zayner said, would have some effect on cells, albeit limited.

Peters goes on to note that Zayner has a PhD in molecular biology and biophysics and worked for NASA (US National Aeronautics and Space Administration). Zayner’s Wikipedia entry fills in a few more details (Note: Links have been removed),

Zayner graduated from the University of Chicago with a Ph.D. in biophysics in 2013. He then spent two years as a researcher at NASA’s Ames Research Center,[2] where he worked on Martian colony habitat design. While at the agency, Zayner also analyzed speech patterns in online chat, Twitter, and books, and found that language on Twitter and online chat is closer to how people talk than to how they write.[3] Zayner found NASA’s scientific work less innovative than he expected, and upon leaving in January 2016, he launched a crowdfunding campaign to provide CRISPR kits to let the general public experiment with editing bacterial DNA. He also continued his grad school business, The ODIN, which sells kits to let the general public experiment at home. As of May 2016, The ODIN had four employees and operates out of Zayner’s garage.[2]

He refers to himself as a biohacker and believes in the importance in letting the general public participate in scientific experimentation, rather than leaving it segregated to labs.[2][4][1] Zayner found the biohacking community exclusive and hierarchical, particularly in the types of people who decide what is “safe”. He hopes that his projects can let even more people experiment in their homes. Other scientists responded that biohacking is inherently privileged, as it requires leisure time and money, and that deviance from the safety rules of concern would lead to even harsher regulations for all.[5] Zayner’s public CRISPR kit campaign coincided with wider scrutiny over genetic modification. Zayner maintained that these fears were based on misunderstandings of the product, as genetic experiments on yeast and bacteria cannot produce a viral epidemic.[6][7] In April 2015, Zayner ran a hoax on Craigslist to raise awareness about the future potential of forgery in forensics genetics testing.[8]

In February 2016, Zayner performed a full body microbiome transplant on himself, including a fecal transplant, to experiment with microbiome engineering and see if he could cure himself from gastrointestinal and other health issues. The microbiome from the donors feces successfully transplanted in Zayner’s gut according to DNA sequencing done on samples.[2] This experiment was documented by filmmakers Kate McLean and Mario Furloni and turned into the short documentary film Gut Hack.[9]

In December 2016, Zayner created a fluorescent beer by engineering yeast to contain the green fluorescent protein from jellyfish. Zayner’s company, The ODIN, released kits to allow people to create their own engineered fluorescent yeast and this was met with some controversy as the FDA declared the green fluorescent protein can be seen as a color additive.[10] Zayner, views the kit as a way that individual can use genetic engineering to create things in their everyday life.[11]

I found the video for Zayner’s now completed crowdfunding campaign,

I also found The ODIN website (mentioned in the Wikipedia essay) where they claim to be selling various gene editing and gene engineering kits including the CRISPR editing kits mentioned in Peters’ article,

In 2016, he [Zayner] sold $200,000 worth of products, including a kit for yeast that can be used to brew glowing bioluminescent beer, a kit to discover antibiotics at home, and a full home lab that’s roughly the cost of a MacBook Pro. In 2017, he expects to double sales. Many kits are simple, and most buyers probably aren’t using the supplies to attempt to engineer themselves (many kits go to classrooms). But Zayner also hopes that as people using the kits gain genetic literacy, they experiment in wilder ways.

Zayner sells a full home biohacking lab that’s roughly the cost of a MacBook Pro. [Photo: The ODIN]

He questions whether traditional research methods, like randomized controlled trials, are the only way to make discoveries, pointing out that in newer personalized medicine (such as immunotherapy for cancer, which is personalized for each patient), a sample size of one person makes sense. At his workshop, he argued that people should have the choice to self-experiment if they want to; we also change our DNA when we drink alcohol or smoke cigarettes or breathe in dirty city air. Other society-sanctioned activities are more dangerous. “We sacrifice maybe a million people a year to the car gods,” he said. “If you ask someone, ‘Would you get rid of cars?’–no.” …

US researchers both conventional and DIY types such as Zayner are not the only ones who are editing genes. The Chinese study mentioned in Peters’ article was written up in an Oct. 19, 2015 article by Antonio Regalado for the MIT [Massachusetts Institute of Technology] Technology Review (Note: Links have been removed),

Scientists in China say they are the first to use gene editing to produce customized dogs. They created a beagle with double the amount of muscle mass by deleting a gene called myostatin.

The dogs have “more muscles and are expected to have stronger running ability, which is good for hunting, police (military) applications,” Liangxue Lai, a researcher with the Key Laboratory of Regenerative Biology at the Guangzhou Institutes of Biomedicine and Health, said in an e-mail.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson’s and muscular dystrophy. “The goal of the research is to explore an approach to the generation of new disease dog models for biomedical research,” says Lai. “Dogs are very close to humans in terms of metabolic, physiological, and anatomical characteristics.”

Lai said his group had no plans breed to breed the extra-muscular beagles as pets. Other teams, however, could move quickly to commercialize gene-altered dogs, potentially editing their DNA to change their size, enhance their intelligence, or correct genetic illnesses. A different Chinese Institute, BGI, said in September it had begun selling miniature pigs, created via gene editing, for $1,600 each as novelty pets.

People have been influencing the genetics of dogs for millennia. By at least 36,000 years ago, early humans had already started to tame wolves and shape the companions we have today. Charles Darwin frequently cited dog breeding in The Origin of Species to demonstrate how evolution gradually occurs by a process of selection. With CRISPR, however, evolution is no longer gradual or subject to chance. It is immediate and under human control.

It is precisely that power that is stirring wide debate and concern over CRISPR. Yet at least some researchers think that gene-edited dogs could put a furry, friendly face on the technology. In an interview this month, George Church, a professor at Harvard University who leads a large effort to employ CRISPR editing, said he thinks it will be possible to augment dogs by using DNA edits to make them live longer or simply make them smarter.

Church said he also believed the alteration of dogs and other large animals could open a path to eventual gene editing of people. “Germline editing of pigs or dogs offers a line into it,” he said. “People might say, ‘Hey, it works.’ ”

In the meantime, Zayner’s ideas are certainly thought provoking. I’m not endorsing either his products or his ideas but it should be noted that early science pioneers such as Humphrey Davy and others experimented on themselves. For anyone unfamiliar with Davy, (from the Humphrey Davy Wikipedia entry; Note: Links have been removed),

Sir Humphry Davy, 1st Baronet PRS MRIA FGS (17 December 1778 – 29 May 1829) was a Cornish chemist and inventor,[1] who is best remembered today for isolating a series of substances for the first time: potassium and sodium in 1807 and calcium, strontium, barium, magnesium and boron the following year, as well as discovering the elemental nature of chlorine and iodine. He also studied the forces involved in these separations, inventing the new field of electrochemistry. Berzelius called Davy’s 1806 Bakerian Lecture On Some Chemical Agencies of Electricity[2] “one of the best memoirs which has ever enriched the theory of chemistry.”[3] He was a Baronet, President of the Royal Society (PRS), Member of the Royal Irish Academy (MRIA), and Fellow of the Geological Society (FGS). He also invented the Davy lamp and a very early form of incandescent light bulb.

Canadian content*

A Nov. 11, 2017 posting on the Canadian Broadcasting Corporation’s (CBC) Quirks and Quarks blog notes that self-experimentation has a long history and goes on to describe Zayner’s and others biohacking exploits before describing the legality of biohacking in Canada,

With biohackers entering into the space traditionally held by scientists and clinicians, it begs questions. Professor Timothy Caulfield, a Canada research chair in health, law and policy at the University of Alberta, says when he hears of somebody giving themselves biohacked gene therapy, he wonders: “Is this legal? Is this safe? And if it’s not safe, is there anything that we can do about regulating it? And to be honest with you that’s a tough question and I think it’s an open question.”

In Canada, Caulfield says, Health Canada focuses on products. “You have to have something that you are going to regulate or you have to have something that’s making health claims. So if there is a product that is saying I can cure X, Y, or Z, Health Canada can say, ‘Well let’s make sure the science really backs up that claim.’ The problem with these do-it-yourself approaches is there isn’t really a product. You know these people are experimenting on themselves with something that may or may not be designed for health purposes.”

According to Caufield, if you could buy a gene therapy kit that was being marketed to you to biohack yourself, that would be different. “Health Canada could jump in. But right here that’s not the case,” he says.

There are places in the world that do regulate biohacking, says Caulfield. “Germany, for example, they have specific laws for it. And here in Canada we do have a regulatory framework that says that you cannot do gene therapy that will alter the germ line. In other words, you can’t do gene therapy or any kind of genetic editing that will create a change that you will pass on to your offspring. So that would be illegal, but that’s not what’s happening here. And I don’t think there’s a regulatory framework that adequately captures it.”

Infectious disease and policy experts aren’t that concerned yet about the possibility of a biohacker unleashing a genetically modified super germ into the population.

“I think in the future that could be a problem,”says Caulfield, “but this isn’t something that would be easy to do in your garage. I think it’s complicated science. But having said that, the science is moving quickly. We need to think about how we are going to control the potential harms.”

You can find out more about the ‘wild’ people (mostly men) of early science in Richard Holmes’ 2008 book, The Age of Wonder: How the Romantic Generation Discovered the Beauty and Terror of Science.

Finally, should you be interested in connecting with synthetic biology enthusiasts, entrepreneurs, and others, SynBioBeta is more than a conference; it’s also an activity hub.

ETA January 25, 2018 (five minutes later): There are some CRISPR/CAS9 events taking place in Toronto, Canada on January 24 and 25, 2018. One is a workshop with Portuguese artist, Marta de Menezes, and the other is a panel discussion. See my January 10, 2018 posting for more details.

*’Segue: There is some Canadian content if you keep reading.’ and ‘Canadian content’ added January 25, 2018 six minutes after first publication.

ETA February 20, 2018: Sarah Zhang’s Feb. 20, 2018 article for The Atlantic revisits Josiah Zayner’s decision to inject himself with CRISPR,

When Josiah Zayner watched a biotech CEO drop his pants at a biohacking conference and inject himself with an untested herpes treatment, he realized things had gone off the rails.

Zayner is no stranger to stunts in biohacking—loosely defined as experiments, often on the self, that take place outside of traditional lab spaces. You might say he invented their latest incarnation: He’s sterilized his body to “transplant” his entire microbiome in front of a reporter. He’s squabbled with the FDA about selling a kit to make glow-in-the-dark beer. He’s extensively documented attempts to genetically engineer the color of his skin. And most notoriously, he injected his arm with DNA encoding for CRISPR that could theoretically enhance his muscles—in between taking swigs of Scotch at a live-streamed event during an October conference. (Experts say—and even Zayner himself in the live-stream conceded—it’s unlikely to work.)

So when Zayner saw Ascendance Biomedical’s CEO injecting himself on a live-stream earlier this month, you might say there was an uneasy flicker of recognition.

“Honestly, I kind of blame myself,” Zayner told me recently. He’s been in a soul-searching mood; he recently had a kid and the backlash to the CRISPR stunt in October [2017] had been getting to him. “There’s no doubt in my mind that somebody is going to end up hurt eventually,” he said.

Yup, it’s one of the reasons for rules; people take things too far. The trick is figuring out how to achieve balance between risk taking and recklessness.