Tag Archives: shapeshifting

4D printing, what is that?

According to an April 12, 2017 news item on ScienceDaily, shapeshifting in response to environmental stimuli is the fourth dimension (I have a link to a posting about 4D printing with another fourth dimension),

A team of researchers from Georgia Institute of Technology and two other institutions has developed a new 3-D printing method to create objects that can permanently transform into a range of different shapes in response to heat.

The team, which included researchers from the Singapore University of Technology and Design (SUTD) and Xi’an Jiaotong University in China, created the objects by printing layers of shape memory polymers with each layer designed to respond differently when exposed to heat.

“This new approach significantly simplifies and increases the potential of 4-D printing by incorporating the mechanical programming post-processing step directly into the 3-D printing process,” said Jerry Qi, a professor in the George W. Woodruff School of Mechanical Engineering at Georgia Tech. “This allows high-resolution 3-D printed components to be designed by computer simulation, 3-D printed, and then directly and rapidly transformed into new permanent configurations by simply heating.”

The research was reported April 12 [2017] in the journal Science Advances, a publication of the American Association for the Advancement of Science. The work is funded by the U.S. Air Force Office of Scientific Research, the U.S. National Science Foundation and the Singapore National Research Foundation through the SUTD DManD Centre.

An April 12, 2017 Singapore University of Technology and Design (SUTD) press release on EurekAlert provides more detail,

4D printing is an emerging technology that allows a 3D-printed component to transform its structure by exposing it to heat, light, humidity, or other environmental stimuli. This technology extends the shape creation process beyond 3D printing, resulting in additional design flexibility that can lead to new types of products which can adjust its functionality in response to the environment, in a pre-programmed manner. However, 4D printing generally involves complex and time-consuming post-processing steps to mechanically programme the component. Furthermore, the materials are often limited to soft polymers, which limit their applicability in structural scenarios.

A group of researchers from the SUTD, Georgia Institute of Technology, Xi’an Jiaotong University and Zhejiang University has introduced an approach that significantly simplifies and increases the potential of 4D printing by incorporating the mechanical programming post-processing step directly into the 3D printing process. This allows high-resolution 3D-printed components to be designed by computer simulation, 3D printed, and then directly and rapidly transformed into new permanent configurations by using heat. This approach can help save printing time and materials used by up to 90%, while completely eliminating the time-consuming mechanical programming process from the design and manufacturing workflow.

“Our approach involves printing composite materials where at room temperature one material is soft but can be programmed to contain internal stress, and the other material is stiff,” said Dr. Zhen Ding of SUTD. “We use computational simulations to design composite components where the stiff material has a shape and size that prevents the release of the programmed internal stress from the soft material after 3D printing. Upon heating, the stiff material softens and allows the soft material to release its stress. This results in a change – often dramatic – in the product shape.” This new shape is fixed when the product is cooled, with good mechanical stiffness. The research demonstrated many interesting shape changing parts, including a lattice that can expand by almost 8 times when heated.

This new shape becomes permanent and the composite material will not return to its original 3D-printed shape, upon further heating or cooling. “This is because of the shape memory effect,” said Prof. H. Jerry Qi of Georgia Tech. “In the two-material composite design, the stiff material exhibits shape memory, which helps lock the transformed shape into a permanent one. Additionally, the printed structure also exhibits the shape memory effect, i.e. it can then be programmed into further arbitrary shapes that can always be recovered to its new permanent shape, but not its 3D-printed shape.”

Said SUTD’s Prof. Martin Dunn, “The key advance of this work, is a 4D printing method that is dramatically simplified and allows the creation of high-resolution complex 3D reprogrammable products; it promises to enable myriad applications across biomedical devices, 3D electronics, and consumer products. It even opens the door to a new paradigm in product design, where components are designed from the onset to inhabit multiple configurations during service.”

Here’s a video,


Uploaded on Apr 17, 2017

A research team led by the Singapore University of Technology and Design’s (SUTD) Associate Provost of Research, Professor Martin Dunn, has come up with a new and simplified 4D printing method that uses a 3D printer to rapidly create 3D objects, which can permanently transform into a range of different shapes in response to heat.

Here’s a link to and a citation for the paper,

Direct 4D printing via active composite materials by Zhen Ding, Chao Yuan, Xirui Peng, Tiejun Wang, H. Jerry Qi, and Martin L. Dunn. Science Advances  12 Apr 2017: Vol. 3, no. 4, e1602890 DOI: 10.1126/sciadv.1602890

This paper is open access.

Here is a link to a post about another 4th dimension, time,

4D printing: a hydrogel orchid (Jan. 28, 2016)

Heat, evolution, and the shape of gold nanorods

A Feb. 23, 2015 news item on Azonano features gold nanorods and their shapeshifting ways when releasing heat,

Researchers at the U.S. Department of Energy’s Argonne National Laboratory have revealed previously unobserved behaviors that show how details of the transfer of heat at the nanoscale cause nanoparticles to change shape in ensembles.

The new findings depict three distinct stages of evolution in groups of gold nanorods, from the initial rod shape to the intermediate shape to a sphere-shaped nanoparticle. The research suggests new rules for the behavior of nanorod ensembles, providing insights into how to increase heat transfer efficiency in a nanoscale system.

A Feb. 18, 2015 Argonne National Laboratory news release by Justin H. S. Breaux, which originated the news item, provides more details about the work,

At the nanoscale, individual gold nanorods have unique electronic, thermal and optical properties. Understanding these properties and managing how collections of these elongated nanoparticles absorb and release this energy as heat will drive new research towards next-generation technologies such as water purification systems, battery materials and cancer research.

A good deal is known about how single nanorods behave—but little is known about how nanorods behave in ensembles of millions. Understanding how the individual behavior of each nanorod, including how its orientation and rate of transition differ from those around it, impacts the collective kinetics of the ensemble and is critical to using nanorods in future technologies.

“We started with a lot of questions,” said Argonne physicist Yuelin Li, “like ‘How much power can the particles sustain before losing functionality? How do individual changes at the nanoscale affect the overall functionality? How much heat is released to the surrounding area?’ Each nanorod is continuously undergoing a change in shape when heated beyond melting temperature, which means a change in the surface area and thus a change in its thermal and hydrodynamic properties.”

The researchers used a laser to heat the nanoparticles and X-rays to analyze their changing shapes. Generally, nanorods transition into nanospheres more quickly when supplied with a higher intensity of laser power. In this case, completely different ensemble behaviors were observed when this intensity increased incrementally. The intensity of the heat applied changes not only the nanoparticles’ shape at various rates but also affects their ability to efficiently absorb and release heat.

“For us, the key was to understand just how efficient the nanorods were at transferring light into heat in many different scenarios,” said nanoscientist Subramanian Sankaranarayanan of Argonne’s Center for Nanoscale Materials. “Then we had to determine the physics behind how heat was transferred and all the different ways these nanorods could transition into nanospheres.”

To observe how the rod makes this transition, researchers first shine a laser pulse at the nanorod suspended in a water solution at Argonne’s Advanced Photon Source. The laser lasts for less than a hundred femtoseconds, nearly one trillion times faster than a blink of the eye. What follows is a series of focused and rapid X-ray bursts using a technique called small angle X-ray scattering. The resulting data is used to determine the average shape of the particle as it changes over time.

In this way, scientists can reconstruct the minute changes occurring in the shape of the nanorod. However, to understand the physics underlying this phenomenon, the researchers needed to look deeper at how individual atoms vibrate and move during the transition. For this, they turned to the field of molecular dynamics using the supercomputing power of the 10-petaflop Mira supercomputer at the Argonne Leadership Computing Facility.

Mira used mathematical equations to pinpoint the individual movements of nearly two million of the nanorods’ atoms in the water. Using factors such as the shape, temperature and rate of change, the researchers built simulations of the nanorod in many different scenarios to see how the structure changes over time.

“In the end,” said Sankaranarayanan, “we discovered the heat transfer rates for shorter but wider nanospheres are lower than for their rod-shaped predecessors. This decrease in heat transfer efficiency at the nanoscale plays a key role in accelerating the transition from rod to sphere when heated beyond the melting temperature.”

Here’s a link to and a citation for the paper,

Femtosecond Laser Pulse Driven Melting in Gold Nanorod Aqueous Colloidal Suspension: Identification of a Transition from Stretched to Exponential Kinetics by Yuelin Li, Zhang Jiang, Xiao-Min Lin, Haidan Wen, Donald A. Walko, Sanket A. Deshmukh, Ram Subbaraman, Subramanian K. R. S. Sankaranarayanan, Stephen K. Gray, & Phay Ho. Scientific Reports 5, Article number: 8146 doi:10.1038/srep08146 Published 30 January 2015

This article is open access.

Dimpling can be more than cute, morphable surfaces (smorphs) from MIT (Massachusetts Institute of Technology)

A morphable surface developed by an MIT team can change surface texture — from smooth to dimply, and back again — through changes in pressure. When the inside pressure is reduced, the flexible material shrinks, and the stiffer outer layer wrinkles. Increasing pressure returns the surface to a smooth state.

A June 24, 2014 news item on Nanowerk features a story about the origins of the dimpled golf ball, aerodynamics, and some very pink material (Note: A link has been removed),

There is a story about how the modern golf ball, with its dimpled surface, came to be: In the mid-1800s, it is said, new golf balls were smooth, but became dimpled over time as impacts left permanent dents. Smooth new balls were typically used for tournament play, but in one match, a player ran short, had to use an old, dented one, and realized that he could drive this dimpled ball much further than a smooth one.

Whether that story is true or not, testing over the years has proved that a golf ball’s irregular surface really does dramatically increase the distance it travels, because it can cut the drag caused by air resistance in half. Now researchers at MIT are aiming to harness that same effect to reduce drag on a variety of surfaces — including domes that sometimes crumple in high winds, or perhaps even vehicles.

Detailed studies of aerodynamics have shown that while a ball with a dimpled surface has half the drag of a smooth one at lower speeds, at higher speeds that advantage reverses. So the ideal would be a surface whose smoothness can be altered, literally, on the fly — and that’s what the MIT team has developed.

The new work is described in a paper in the journal Advanced Materials (“Smart Morphable Surfaces for Aerodynamic Drag Control”) by MIT’s Pedro Reis and former MIT postdocs Denis Terwagne (now at the Université Libre de Bruxelles in Belgium) and Miha Brojan (now at the University of Ljubljana in Slovenia).

esearchers made this sphere to test their concept of morphable surfaces. Made of soft polymer with a hollow center, and a thin coating of a stiffer polymer, the sphere becomes dimpled when the air is pumped out of the hollow center, causing it to shrink. (Photo courtesy of the MIT researchers)

Researchers made this sphere to test their concept of morphable surfaces. Made of soft polymer with a hollow center, and a thin coating of a stiffer polymer, the sphere becomes dimpled when the air is pumped out of the hollow center, causing it to shrink. (Photo courtesy of the MIT researchers)

A June 24, 2014 MIT (Massachusetts Institute of Technology) news release (also on EurekAlert) by David Chandler, which originated the news item, provides more detail about the work,

The ability to change the surface in real time comes from the use of a multilayer material with a stiff skin and a soft interior — the same basic configuration that causes smooth plums to dry into wrinkly prunes. To mimic that process, Reis and his team made a hollow ball of soft material with a stiff skin — with both layers made of rubberlike materials — then extracted air from the hollow interior to make the ball shrink and its surface wrinkle.

“Numerous studies of wrinkling have been done on flat surfaces,” says Reis, an assistant professor of mechanical engineering and civil and environmental engineering. “Less is known about what happens when you curve the surface. How does that affect the whole wrinkling process?”

The answer, it turns out, is that at a certain degree of shrinkage, the surface can produce a dimpled pattern that’s very similar to that of a golf ball — and with the same aerodynamic properties.

The aerodynamic properties of dimpled balls can be a bit counterintuitive: One might expect that a ball with a smooth surface would sail through the air more easily than one with an irregular surface. The reason for the opposite result has to do with the nature of a small layer of the air next to the surface of the ball. The irregular surface, it turns out, holds the airflow close to the ball’s surface longer, delaying the separation of this boundary layer. This reduces the size of the wake — the zone of turbulence behind the ball — which is the primary cause of drag for blunt objects.

When the researchers saw the wrinkled outcomes of their initial tests with their multilayer spheres, “We realized that these samples look just like golf balls,” Reis says. “We systematically tested them in a wind tunnel, and we saw a reduction in drag very similar to that of golf balls.”

Because the surface texture can be controlled by adjusting the balls’ interior pressure, the degree of drag reduction can be controlled at will. “We can generate that surface topography, or erase it,” Reis says. “That reversibility is why this is pretty interesting; you can switch the drag-reducing effect on and off, and tune it.”

As a result of that variability, the team refers to these as “smart morphable surfaces” — or “smorphs,” for short. The pun is intentional, Reis says: The paper’s lead author — Terwagne, a Belgian comics fan — pointed out that one characteristic of Smurfs cartoon characters is that no matter how old they get, they never develop wrinkles.

Terwagne says that making the morphable surfaces for lab testing required a great deal of trial-and-error — work that ultimately yielded a simple and efficient fabrication process. “This beautiful simplicity to achieve a complex functionality is often used by nature,” he says, “and really inspired me to investigate further.”

Many researchers have studied various kinds of wrinkled surfaces, with possible applications in areas such as adhesion, or even unusual optical properties. “But we are the first to use wrinkling for aerodynamic properties,” Reis says.

The drag reduction of a textured surface has already expanded beyond golf balls: The soccer ball being used at this year’s World Cup, for example, uses a similar effect; so do some track suits worn by competitive runners. For many purposes, such as in golf and soccer, constant dimpling is adequate, Reis says.

But in other uses, the ability to alter a surface could prove useful: For example, many radar antennas are housed in spherical domes, which can collapse catastrophically in very high winds. A dome that could alter its surface to reduce drag when strong winds are expected might avert such failures, Reis suggests. Another application could be the exterior of automobiles, where the ability to adjust the texture of panels to minimize drag at different speeds could increase fuel efficiency, he says.

Delightful is not the first adjective that jumps to my mind when describing this work but I’m not an engineer (from the news release),

John Rogers, a professor of materials research and engineering at the University of Illinois at Urbana-Champaign who was not involved in this work, says, “It represents a delightful example of how controlled processes of mechanical buckling can be used to create three-dimensional structures with interesting aerodynamic properties. The type of dynamic tuning of sophisticated surface morphologies made possible by this approach would be difficult or impossible to achieve in any other way.”

Here’s a link to and a citation for the paper,

Smart Morphable Surfaces for Aerodynamic Drag Control by Denis Terwagne, Miha Brojan, and Pedro M. Reis. Advanced Materials DOI: 10.1002/adma.201401403 Article first published online: 23 JUN 2014

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

This paper is behind a paywall.

Shapeshifting, paradigm shifting nanoparticles

Scientists at the University of California at San Diego (UCSD) had approached the problem of targeting diseased cells in a new way, according to the May 28, 2013 UCSD news release (also available on EurekAlert) by Susan Brown,

Targeting treatments specifically to cancerous or other diseased cells depends on some means of accumulating high levels of a drug or other therapeutic agent at the specific site and keeping it there. Most efforts so far depend on matching a piece of the drug-delivering molecule to specific receptors on the surface of the target cell.

Inspiration for this new strategy came from biological systems that use shape to alter the ability of something to lock in place or slip away and escape, said Nathan Gianneschi, a professor of chemistry and biochemistry, who led the project.

“We wanted to come up with a new approach,” Gianneschi said. “Specifically, we wanted to design switchable materials that we could inject in one shape and have them change to another between the blood and tumors.”

Here’s how they did it,

Some cancerous tissues produce high levels of a class of molecules called MMPs, for matrix metalloproteinases. These enzymes change how other proteins behave by altering their molecular configuration, leading to metastasis. Gianneschi and colleagues harnessed this ability to alter their nanoparticles in ways that would cause them to linger at the site of the tumor.

“We figured out how to make an autonomous material that could sense its environment and change accordingly,” Gianneschi said.

Each nanoparticle is made of many detergent-like molecules with one end that mixes readily with water and another that repels it. In solution, they self assemble into balls with the water-repellant ends inside, and in that configuration can easily be injected into a vein.

When mixed with MMPs in vials, the enzymes nicked the peptides on the surface of the spheres, which reassembled into netlike threads.

The team tested the concept further by injecting their new nanoparticles into mice with human fibrosarcomas, a kind of cancer that produces high levels of MMPs.

To mark when the spheres broke down to form other structures, the chemists placed one of two fluorecent dyes, rhodamine or fluorescein, inside the spheres. In close proximity, the dyes interact to create a specific light signal called FRET for Förster Resonance Energy Transfer, when energy jumps from rhodamine to fluorescein.

Within a day they detected FRET signals indicating that the spheres had reassembled at the sites of the tumors, and the signal persisted for at least a week.

The treatment is not inherently toxic. [emphasis mine] It did not appear to change the tumors in any way, and liver and kidney, the organs most vulnerable to collateral damage from treatments because they clear toxins from the body, were normal and healthy eight days after injection.

Different versions of these nanoparticles could be designed to respond to signals inherent to other types of cancers and inflamed tissue, the authors say. The spheres can also be engineered to carry drugs, or different diagnostic probes.

Right now, this same team is developing nanoparticles that carry an infrared dye, which would enable them to visualize tumors deeper inside the body along with other materials that can be imaged with instruments commonly available in the clinic.

I’m not sure I’d call this a ‘treatment’, it seems more like a new technique for drug delivery, diagnosis, etc. That quibble aside, this sounds very exciting and I hope the researchers will be able to start human clinical trials in the near future.

For those who’d like to read the research,

Enzyme-Directed Assembly of a Nanoparticle Probe in Tumor Tissue by Miao-Ping Chien, Matthew P. Thompson, Christopher V. Barback, David J. Hall, and Nathan C. Gianneschi.
ADVANCED MATERIALS, 2013, DOI: 10.1002/adma.201300823

This paper is behind a paywall.

Shapeshifting on demand but no stretching yet: morphees

This research (Morphees) is from Bristol University where researchers have created prototypes for shapeshifting mobile devices,

A high-fidelity prototype using projection and tracking on wood tiles that are actuated with thin shape-memory alloy wires [downloaded from http://www.bris.ac.uk/news/2013/9332.html/]

A high-fidelity prototype using projection and tracking on wood tiles that are actuated with thin shape-memory alloy wires [downloaded from http://www.bris.ac.uk/news/2013/9332.html/]

The Apr. 28, 2013 news release on EurekAlert provides more detail,

The research, led by Dr Anne Roudaut and Professor Sriram Subramanian, from the University of Bristol’s Department of Computer Science, have used ‘shape resolution’ to compare the resolution of six prototypes the team have built using the latest technologies in shape changing material, such as shape memory alloy and electro active polymer.

One example of a device is the team’s concept of Morphees, self-actuated flexible mobile devices that can change shape on-demand to better fit the many services they are likely to support.

The team believe Morphees will be the next generation of mobile devices, where users can download applications that embed a dedicated form factor, for instance the “stress ball app” that collapses the device in on itself or the “game app” that makes it adopt a console-like shape.

Dr Anne Roudaut, Research Assistant in the Department of Computer Science’s Bristol Interaction and Graphics group, said: “The interesting thing about our work is that we are a step towards enabling our mobile devices to change shape on-demand. Imagine downloading a game application on the app-store and that the mobile phone would shape-shift into a console-like shape in order to help the device to be grasped properly. The device could also transform into a sphere to serve as a stress ball, or bend itself to hide the screen when a password is being typed so passers-by can’t see private information.”

By comparing the shape resolution of their prototypes, the researchers have created insights to help designers towards creating high shape resolution Morphees.

In the future the team hope to build higher shape resolution Morphees by investigating the flexibility of materials. They are also interested in exploring other kinds of deformations that the prototypes did not explore, such as porosity and stretchability.

Here’s the video where the researchers demonstrate their morphees,


The work will be presented at ACM CHI 2013, sometime between Saturday 27 April to Thursday 2 May 2013, in Paris, France. For those who’d like to see the paper which will be presented, here’s a link to it,

Morphees: Toward High “Shape Resolution” in Self-Actuated Flexible Mobile Devices by
Anne Roudaut, Abhijit Karnik, Markus Löchtefeld, and Sriram Subramanian

After reading the news release and watching the video, I am reminded of the ‘morph’ concept, a shapeshifting, wearable device proposed by Cambridge University and Nokia. Last I wrote about that project, they had announced a stretchable skin, as per my Nov. 7, 2011 posting.

For those who are interested in what ACM CHI 2013 is all about, from the home page,

The ACM SIGCHI Conference on Human Factors in Computing Systems is the premier international conference on human-computer interaction. CHI 2013 is about changing perspectives: we draw from the constantly changing perspectives of the diverse CHI community and beyond, but we also change perspectives, offering new visions of people interacting with technology. The conference is multidisciplinary, drawing from science, engineering and design, with contributions from research and industry in 15 different venues. CHI brings together students and experts from over 60 countries, representing different cultures and different application areas, whose diverse perspectives influence each other.

CHI 2013 is located in vibrant Paris, France, the most visited city in the world. The conference will be held at the Palais de Congrès de Paris. First in Europe in research and development, with the highest concentration of higher education students in Europe, Paris is a world-class center for business and culture, with over 3800 historical monuments.The Louvre’s pyramid captures the spirit of CHI’13, offering diverse perspectives on design and technology, contrasting the old and new. The simple glass sides reveal inner complexity, sometimes transparent, sometimes reflecting the people and buildings that surround it, in the constantly
changing Paris light.

CHI 2013 welcomes works addressing research on all aspects of human-computer interaction (HCI), as well as case studies of interactive system designs, innovative proof-of-concept, and presentations by experts on the latest challenges and innovations in the field. In addition to a long-standing focus on professionals in design, engineering, management, and user experience; this year’s conference has made special efforts to serve communities in the areas of: design, management, engineering, user experience, arts, sustainability, children, games and health. We look forward to seeing you at CHI 2013 in Paris!

As I recall, ACM stands for Association of Computing Machinery, CHI stands for computer-human interface, and SIG stands for Special Interest Group.

ETA May 13, 2013: I meant to do this two weeks ago (Apr. 30,2013), ah well. Roel Vertegaal and his team at Canada’s Queen’s University introduced something called a MorePhone, which can curl up and change shape, at the CHI 2013. From the Apr. 30, 2013 news release on EurekAlert*,

Researchers at Queen’s University’s Human Media Lab have developed a new smartphone – called MorePhone – which can morph its shape to give users a silent yet visual cue of an incoming phone call, text message or email.

“This is another step in the direction of radically new interaction techniques afforded by smartphones based on thin film, flexible display technologies” says Roel Vertegaal (School of Computing), director of the Human Media Lab at Queen’s University who developed the flexible PaperPhone and PaperTab.

“Users are familiar with hearing their phone ring or feeling it vibrates in silent mode. One of the problems with current silent forms of notification is that users often miss notifications when not holding their phone. With MorePhone, they can leave their smartphone on the table and observe visual shape changes when someone is trying to contact them.”

MorePhone is not a traditional smartphone. It is made of a thin, flexible electrophoretic display manufactured by Plastic Logic – a British company and a world leader in plastic electronics. Sandwiched beneath the display are a number of shape memory alloy wires that contract when the phone notifies the user. This allows the phone to either curl either its entire body, or up to three individual corners. Each corner can be tailored to convey a particular message. For example, users can set the top right corner of the MorePhone to bend when receiving a text message, and the bottom right corner when receiving an email. Corners can also repeatedly bend up and down to convey messages of greater urgency.

I have written about Vertegaal and his team’s ‘paper’ devices previously. The most recent piece is this Jan. 9, 2013 posting, Canada’s Queen’s University strikes again with its ‘paper’ devices. You can find out more about Plastic Logic here.

*’Eurkealert’ changed to ‘EurekAlert’ on Feb. 17, 2016.

US Air Force takes baby steps toward shapeshifting materials

When I see information about US military futuristic projects it’s usually from the US Army’s DARPA (Defense Advanced Research Projects Agency).  Consequently, I was surprised to notice that this shapeshifting project is being funded by the US Air Force Office of Scientific Research according to the July 11, 2012 news item on phys.org,

An international research team has received a $2.9 million grant from the Air Force Office of Scientific Research to design nanomaterials whose internal structure changes shape in response to stimuli such as heat or light.

Each of these novel materials will be constructed from three types of components: inorganic nanoparticles with desired optical or electrical properties; peptides that bond to these nanoparticles; and special molecules called spacers, which sit between the peptides and bend in the presence of heat, light or other triggers.

When stimulated, the spacers will cause the arrangement of nanoparticles within the material to morph — a process that can lead to interesting and useful effects.

Shape-shifting materials of the kind the researchers are planning to create could have use in applications including color-changing sensors and plasmonic circuits that divert light in two directions.

The news item originated from a July 11, 2012 news release from the State University of New York (SUNY) at Buffalo,

The project is being led by Paras Prasad, SUNY Distinguished Professor in the University at Buffalo’s departments of chemistry, physics, electrical engineering and medicine, and executive director of UB’s Institute for Lasers, Photonics and Biophotonics (ILPB). …

Prasad’s fellow investigators include Aidong Zhang, professor and chair of the Department of Computer Science and Engineering at UB; Mark T. Swihart, professor of chemical and biological engineering at UB and director of the UB 2020 Integrated Nanostructured Systems Strategic Strength; Tiffany R. Walsh, associate professor at the Institute for Frontier Materials at Deakin University in Australia; and Marc R. Knecht, associate professor of chemistry at the University of Miami.

The palette of parts the team will use to build the nanomaterials includes spacers of different sizes, along with seven types of nanoparticles — gold, silver, silica, iron-oxide, iron-platinum, cadmium-sulfide and zinc-sulfide.

To identify the combinations of components that will produce the most interesting materials, the scientists will use high-throughput experiments and data-mining techniques to screen and analyze the vast number of possible combinations of nanostructures, biomolecular linking elements (the peptides) and assembly conditions.

“One of our goals is to contribute to the fundamental understanding of how the spatial arrangement of nanoscale components in materials affects their optical, magnetic and plasmonic properties,” Prasad said. “The high-throughput techniques we are using were pioneered in the field of bioinformatics, but also have extraordinary promise in the exploration of advanced materials.”

Zhang said, “The computational capabilities offered by informatics and data mining will enable us to maximize the value of our data regarding the nanoassemblies, to generate and to construct new assemblies that span a wide range of inorganic and bimolecular components so as to achieve desired combinatorics-based properties.”

It’s not exactly the shapeshifting one sees in science fiction but this will be the real stuff (not to be confused with The Right Stuff, a 1983 movie about the US space travel programme of the late 1950s to 1960s).

Folding, origami, and shapeshifting and an article with over 50,000 authors

I’m on a metaphor kick these days so here goes, origami (Japanese paper folding), and shapeshifting are metaphors used to describe a certain biological process that nanoscientists from fields not necessarily associated with biology find fascinating, protein folding.

Origami

Take for example a research team at the California Institute of Technology (Caltech) working to exploit the electronic properties of carbon nanotubes (mentioned in a Nov. 9, 2010 news item on Nanowerk). One of the big issues is that since all of the tubes in a sample are made of carbon getting one tube to react on its own without activating the others is quite challenging when you’re trying to create nanoelectronic circuits. The research team decided to use a technique developed in a bioengineering lab (from the news item),

DNA origami is a type of self-assembled structure made from DNA that can be programmed to form nearly limitless shapes and patterns (such as smiley faces or maps of the Western Hemisphere or even electrical diagrams). Exploiting the sequence-recognition properties of DNA base paring, DNA origami are created from a long single strand of viral DNA and a mixture of different short synthetic DNA strands that bind to and “staple” the viral DNA into the desired shape, typically about 100 nanometers (nm) on a side.

Single-wall carbon nanotubes are molecular tubes composed of rolled-up hexagonal mesh of carbon atoms. With diameters measuring less than 2 nm and yet with lengths of many microns, they have a reputation as some of the strongest, most heat-conductive, and most electronically interesting materials that are known. For years, researchers have been trying to harness their unique properties in nanoscale devices, but precisely arranging them into desirable geometric patterns has been a major stumbling block.

… To integrate the carbon nanotubes into this system, the scientists colored some of those pixels anti-red, and others anti-blue, effectively marking the positions where they wanted the color-matched nanotubes to stick. They then designed the origami so that the red-labeled nanotubes would cross perpendicular to the blue nanotubes, making what is known as a field-effect transistor (FET), one of the most basic devices for building semiconductor circuits.

Although their process is conceptually simple, the researchers had to work out many kinks, such as separating the bundles of carbon nanotubes into individual molecules and attaching the single-stranded DNA; finding the right protection for these DNA strands so they remained able to recognize their partners on the origami; and finding the right chemical conditions for self-assembly.

After about a year, the team had successfully placed crossed nanotubes on the origami; they were able to see the crossing via atomic force microscopy. These systems were removed from solution and placed on a surface, after which leads were attached to measure the device’s electrical properties. When the team’s simple device was wired up to electrodes, it indeed behaved like a field-effect transistor

Shapeshifting

For another more recent example (from an August 5, 2010 article on physorg.com by Larry Hardesty,  Shape-shifting robots),

By combining origami and electrical engineering, researchers at MIT and Harvard are working to develop the ultimate reconfigurable robot — one that can turn into absolutely anything. The researchers have developed algorithms that, given a three-dimensional shape, can determine how to reproduce it by folding a sheet of semi-rigid material with a distinctive pattern of flexible creases. To test out their theories, they built a prototype that can automatically assume the shape of either an origami boat or a paper airplane when it receives different electrical signals. The researchers reported their results in the July 13 issue of the Proceedings of the National Academy of Sciences.

As director of the Distributed Robotics Laboratory at the Computer Science and Artificial Intelligence Laboratory (CSAIL), Professor Daniela Rus researches systems of robots that can work together to tackle complicated tasks. One of the big research areas in distributed robotics is what’s called “programmable matter,” the idea that small, uniform robots could snap together like intelligent Legos to create larger, more versatile robots.

Here’s a video from this site at MIT (Massachusetts Institute of Technology) describing the process,

Folding and over 50, 000 authors

With all this I’ve been leading up to a fascinating project, a game called Foldit, that a team from the University of Washington has published results from in the journal Nature (Predicting protein structures with a multiplayer online game), Aug. 5, 2010.

With over 50,000 authors, this study is a really good example of citizen science (discussed in my May 14, 2010 posting and elsewhere here) and how to use games to solve science problems while exploiting a fascination with folding and origami. From the Aug. 5, 2010 news item on Nanowerk,

The game, Foldit, turns one of the hardest problems in molecular biology into a game a bit reminiscent of Tetris. Thousands of people have now played a game that asks them to fold a protein rather than stack colored blocks or rescue a princess.

Scientists know the pieces that make up a protein but cannot predict how those parts fit together into a 3-D structure. And since proteins act like locks and keys, the structure is crucial.

At any moment, thousands of computers are working away at calculating how physical forces would cause a protein to fold. But no computer in the world is big enough, and computers may not take the smartest approach. So the UW team tried to make it into a game that people could play and compete. Foldit turns protein-folding into a game and awards points based on the internal energy of the 3-D protein structure, dictated by the laws of physics.

Tens of thousands of players have taken the challenge. The author list for the paper includes an acknowledgment of more than 57,000 Foldit players, which may be unprecedented on a scientific publication.

“It’s a new kind of collective intelligence, as opposed to individual intelligence, that we want to study,”Popoviç [principal investigator Zoran Popoviç, a UW associate professor of computer science and engineering] said. “We’re opening eyes in terms of how people think about human intelligence and group intelligence, and what the possibilities are when you get huge numbers of people together to solve a very hard problem.”

There’s a more at Nanowerk including a video about the gamers and the scientists. I think most of us take folding for granted and yet it stimulates all kinds of research and ideas.