Tag Archives: University of Edinburgh

Gene editing to identify and change parts of chicken DNA and limit the spread of bird flu virus

This news comes from the University of Edinburgh (Scotland). From an October 10, 2023 news item on phys.org, Note: A link has been removed,

Scientists have used gene editing techniques to identify and change parts of chicken DNA that could limit the spread of the bird flu virus in the animals.

Researchers were able to restrict—but not completely block—the virus from infecting chickens by altering a small section of their DNA.

The birds showed no signs that the change in their DNA had any impact on their health or well-being.

The findings are an encouraging step forward, but experts highlight that further gene edits would be needed to produce a chicken population which cannot be infected by bird flu—one of the world’s most costly animal diseases.

An October 10, 2023 University of Edinburgh press release, which originated the news item, provides more detail about this research,

Gene editing

Scientists from University of Edinburgh, Imperial College London and the Pirbright Institute bred the chickens using gene editing techniques to alter the section of DNA responsible for producing the protein ANP32A. During an infection, flu viruses hijack this molecule to help replicate themselves.

When the ANP32A gene-edited chickens were exposed to a normal dose of the H9N2-UDL strain of avian influenza virus – commonly known as bird flu – 9 out of 10 birds remained uninfected and there was no spread to other chickens.

Partial protection

The research team then exposed the gene-edited birds to an artificially high dose of avian influenza virus to further test their resilience.

When exposed to the high dose, half of the group – 5 out of 10 birds – became infected. However, the gene edit did provide some protection, with the amount of virus in the infected gene-edited chickens much lower than the level typically seen during infection in non-gene-edited chickens.

The gene edit also helped to limit onward spread of the virus to just one of four non-gene-edited chickens placed in the same incubator. There was no transmission to gene-edited birds.

Viral evolution

Scientists found that in the ANP32A gene-edited birds, the virus had adapted to enlist the support of two related proteins – ANP32B and ANP32E – to replicate.

Following lab tests, scientists found that some of the mutations enabled the virus to utilise the human version of ANP32, but its replication remained low in cell cultures from the human airway.

Experts say that additional genetic changes would be needed for the virus to infect and spread effectively in humans.

However, the findings demonstrate that the single ANP32A gene edit is not robust enough for application in the production of chickens, according to the team.

Gene editing

Scientists from University of Edinburgh, Imperial College London and the Pirbright Institute bred the chickens using gene editing techniques to alter the section of DNA responsible for producing the protein ANP32A. During an infection, flu viruses hijack this molecule to help replicate themselves.

When the ANP32A gene-edited chickens were exposed to a normal dose of the H9N2-UDL strain of avian influenza virus – commonly known as bird flu – 9 out of 10 birds remained uninfected and there was no spread to other chickens.

Partial protection

The research team then exposed the gene-edited birds to an artificially high dose of avian influenza virus to further test their resilience.

When exposed to the high dose, half of the group – 5 out of 10 birds – became infected. However, the gene edit did provide some protection, with the amount of virus in the infected gene-edited chickens much lower than the level typically seen during infection in non-gene-edited chickens.

The gene edit also helped to limit onward spread of the virus to just one of four non-gene-edited chickens placed in the same incubator. There was no transmission to gene-edited birds.

Viral evolution

Scientists found that in the ANP32A gene-edited birds, the virus had adapted to enlist the support of two related proteins – ANP32B and ANP32E – to replicate.

Following lab tests, scientists found that some of the mutations enabled the virus to utilise the human version of ANP32, but its replication remained low in cell cultures from the human airway.

Experts say that additional genetic changes would be needed for the virus to infect and spread effectively in humans.

However, the findings demonstrate that the single ANP32A gene edit is not robust enough for application in the production of chickens, according to the team.

Further edits

To prevent the emergence of escape viruses – viruses that adapt to evade the gene edit and cause infection – the research team next targeted additional sections of DNA responsible for producing all three proteins – ANP32A, ANP32B and ANP32E – inside lab-grown chicken cells.

In cell cultures in the lab, growth of the virus was successfully blocked in cells with the three gene edits.

The next step will be to try to develop chickens with edits to all three genes. No birds have been produced yet.

The study highlights the importance of responsible gene editing and the need to be alert to the risks of driving viral evolution in unwanted directions if complete resistance is not achieved, experts say.

Bird flu is a major global threat, with a devastating impact in both farmed and wild bird populations. In the UK alone, the current outbreak of H5N1 bird flu has decimated seabird populations and cost the poultry industry more than £100 million in losses.

In rare instances, mutations in the bird flu virus allow it to infect people and cause serious illness. Efforts to control the spread of the disease are urgently needed.

“Bird flu is a great threat to bird populations. Vaccination against the virus poses a number of challenges, with significant practical and cost issues associated with vaccine deployment. Gene-editing offers a promising route towards permanent disease resistance, which could be passed down through generations, protecting poultry and reducing the risks to humans and wild birds. Our work shows that stopping the spread of avian influenza in chickens will need several simultaneous genetic changes.” Professor Mike McGrew, The study’s principal investigator, from the University of Edinburgh’s Roslin Institute

“This work is an exciting collaboration that fuses our expertise in virology with the world-leading genetic capability at the Roslin Institute. Although we haven’t yet got the perfect combination of gene edits to take this approach into the field, the results have told us a lot about how influenza virus functions inside the infected cell and how to slow its replication.” Professor Wendy Barclay, Imperial College London

The research was funded by UKRI-BBSRC, which also provides strategic funding to The Roslin Institute, and was supported by Edinburgh Innovations, the University’s commercialisation service.

Ryan O’Hare’s October 10, 2023 Imperial College London (ICL) press release offers a slightly different perspective on the same work, Note: A link has been removed,

Scientists have successfully used gene editing techniques to limit the spread of bird flu in chickens.

In a UK first, researchers have been able to restrict, but not completely block, the avian influenza virus from infecting the birds by precisely altering a small section of their DNA.

The modified birds showed no signs that the change had any impact on the animals’ health or well-being.

But the researchers say that while the findings are encouraging, further gene edits would be needed to produce chickens which cannot be infected by bird flu.

The study, carried out by researchers from the University of Edinburgh, Imperial College London and the Pirbright Institute, is published in the journal Nature Communications.

Professor Wendy Barclay, Head of the Department of Infectious Disease at Imperial College London, said: “This work is an exciting collaboration that fuses our expertise in virology with the world world-leading genetic capability at the Roslin Institute.

“Although we haven’t yet got the perfect combination of gene edits to take this approach into the field, the results have told us a lot about how influenza virus functions inside the infected cell and how to slow its replication.”

Global Threat

Bird flu is a major global threat, with a devastating impact in both farmed and wild bird populations. In the UK alone, the current outbreak of H5N1 bird flu has decimated seabird populations and cost the poultry industry more than £100 million in losses.

In the latest study, researchers aimed to test whether precise edits to the chicken’s genome could potentially generate birds which are resistant to the virus.

The team bred chickens with small edits to a gene called ANP32A. During an infection, influenza viruses hijack the ANP32A protein to help replicate themselves.

But when the gene-edited birds were exposed to a normal dose of virus (the H9N2 strain of avian influenza), 9 out of 10 birds remained uninfected and there was no spread to other chickens.

When the birds were exposed to an artificially high dose of virus, only half of them became infected. The single gene edit also provided some protection against transmission, with a much lower amount of virus in infected gene-edited birds compared to non-edited birds.

In addition, the edit also helped to limit onward spread of the virus to just one of four non-edited chickens placed in the same incubator. There was no transmission to gene-edited birds.

Triple edits

Analysis revealed that in the edited birds, the virus adapted to enlist the support of two related proteins to replicate – ANP32B and ANP32E.

Following lab tests, the researchers found some of the mutations may enable the virus to utilise the human version of ANP32, but replication remained low in cell cultures from the human airway. The researchers stress that additional genetic changes would be needed for the virus to have the potential to infect and spread effectively in humans.

According to the team, the findings demonstrate that a single gene edit is not robust enough to produce resistant chickens. To prevent the emergence of viruses able to adapt to the single edit, the team next used a triple edit to target additional proteins (ANP32A, ANP32B and ANP32E) in lab-grown chicken cells.

In cell cultures in the lab, growth of the virus was successfully blocked in cells with edits to all three genes. In future, researchers hope to develop chickens with this triple edit, but no birds have been produced at this stage.

According to the researchers, the study highlights the importance of responsible gene editing and the need to be alert to the risks of driving viral evolution in unwanted directions if complete resistance is not achieved, experts say.

Professor Mike McGrew, from the University of Edinburgh’s Roslin Institute and principal investigator of the study, said: “Bird flu is a great threat to bird populations. Vaccination against the virus poses a number of challenges, with significant practical and cost issues associated with vaccine deployment.

“Gene-editing offers a promising route towards permanent disease resistance, which could be passed down through generations, protecting poultry and reducing the risks to humans and wild birds. Our work shows that stopping the spread of avian influenza in chickens will need several simultaneous genetic changes.”

A non-gene-edited chicken (left) pictured next to an ANP32A gene-edited chicken (right). Image credit: Norrie Russell Courtesy: University of Edinburgh

There’s also an October 10, 2023 article by Jon Cohen for Science.org, which gives some idea of how much work it took to get to this point, Note: Links have been removed,

For 3 decades, Helen Sang has tinkered with the genomes of chickens to try to make the birds resistant to the flu viruses that periodically devastate flocks and raise fears of a human pandemic. Now, as an especially virulent strain of avian influenza sweeps through poultry and wild birds around the world, the geneticist at the University of Edinburgh’s Roslin Institute has her first solid success. Using the CRISPR gene editor and recent findings about what makes poultry vulnerable to flu, Sang and colleagues from three other institutions have created chickens that can resist real-life doses of avian flu viruses. “Sticking to it gets you somewhere in the end,” she says.

The result, published today [October 5, 2023] in Nature Communications, is “a long-awaited achievement,” says Jiří Hejnar, a virologist at the Czech Academy of Sciences’s Institute of Molecular Genetics whose group showed in 2020 that CRISPR-edited chickens could resist a cancer-causing virus. But farmers won’t be raising flu-proof chickens anytime soon. The edited birds still became infected when exposed to larger amounts of the flu virus. And the strategy raises a safety concern: chickens edited this way could, in theory, drive the evolution of flu variants better at infecting people. “What this showed is a proof of concept,” says Wendy Barclay, a virologist at Imperial College London who worked on the new study. “But we’re not there yet.”

Here’s a link to and a citation for the paper,

Creating resistance to avian influenza infection through genome editing of the ANP32 gene family by Alewo Idoko-Akoh, Daniel H. Goldhill, Carol M. Sheppard, Dagmara Bialy, Jessica L. Quantrill, Ksenia Sukhova, Jonathan C. Brown, Samuel Richardson, Ciara Campbell, Lorna Taylor, Adrian Sherman, Salik Nazki, Jason S. Long, Michael A. Skinner, Holly Shelton, Helen M. Sang, Wendy S. Barclay & Mike J. McGrew. Nature Communications volume 14, Article number: 6136 (2023) DOI: https://doi.org/10.1038/s41467-023-41476-3 Published: 10 October 2023

This paper is open access.

Graphene goes to the moon

The people behind the European Union’s Graphene Flagship programme (if you need a brief explanation, keep scrolling down to the “What is the Graphene Flagship?” subhead) and the United Arab Emirates have got to be very excited about the announcement made in a November 29, 2022 news item on Nanowerk, Note: Canadians too have reason to be excited as of April 3, 2023 when it was announced that Canadian astronaut Jeremy Hansen was selected to be part of the team on NASA’s [US National Aeronautics and Space Administration] Artemis II to orbit the moon (April 3, 2023 CBC news online article by Nicole Mortillaro) ·

Graphene Flagship Partners University of Cambridge (UK) and Université Libre de Bruxelles (ULB, Belgium) paired up with the Mohammed bin Rashid Space Centre (MBRSC, United Arab Emirates), and the European Space Agency (ESA) to test graphene on the Moon. This joint effort sees the involvement of many international partners, such as Airbus Defense and Space, Khalifa University, Massachusetts Institute of Technology, Technische Universität Dortmund, University of Oslo, and Tohoku University.

The Rashid rover is planned to be launched on 30 November 2022 [Note: the launch appears to have occurred on December 11, 2022; keep scrolling for more about that] from Cape Canaveral in Florida and will land on a geologically rich and, as yet, only remotely explored area on the Moon’s nearside – the side that always faces the Earth. During one lunar day, equivalent to approximately 14 days on Earth, Rashid will move on the lunar surface investigating interesting geological features.

A November 29, 2022 Graphene Flagship press release (also on EurekAlert), which originated the news item, provides more details,

The Rashid rover wheels will be used for repeated exposure of different materials to the lunar surface. As part of this Material Adhesion and abrasion Detection experiment, graphene-based composites on the rover wheels will be used to understand if they can protect spacecraft against the harsh conditions on the Moon, and especially against regolith (also known as ‘lunar dust’).

Regolith is made of extremely sharp, tiny and sticky grains and, since the Apollo missions, it has been one of the biggest challenges lunar missions have had to overcome. Regolith is responsible for mechanical and electrostatic damage to equipment, and is therefore also hazardous for astronauts. It clogs spacesuits’ joints, obscures visors, erodes spacesuits and protective layers, and is a potential health hazard.  

University of Cambridge researchers from the Cambridge Graphene Centre produced graphene/polyether ether ketone (PEEK) composites. The interaction of these composites with the Moon regolith (soil) will be investigated. The samples will be monitored via an optical camera, which will record footage throughout the mission. ULB researchers will gather information during the mission and suggest adjustments to the path and orientation of the rover. Images obtained will be used to study the effects of the Moon environment and the regolith abrasive stresses on the samples.

This moon mission comes soon after the ESA announcement of the 2022 class of astronauts, including the Graphene Flagship’s own Meganne Christian, a researcher at Graphene Flagship Partner the Institute of Microelectronics and Microsystems (IMM) at the National Research Council of Italy.

“Being able to follow the Moon rover’s progress in real time will enable us to track how the lunar environment impacts various types of graphene-polymer composites, thereby allowing us to infer which of them is most resilient under such conditions. This will enhance our understanding of how graphene-based composites could be used in the construction of future lunar surface vessels,” says Sara Almaeeni, MBRSC science team lead, who designed Rashid’s communication system.

“New materials such as graphene have the potential to be game changers in space exploration. In combination with the resources available on the Moon, advanced materials will enable radiation protection, electronics shielding and mechanical resistance to the harshness of the Moon’s environment. The Rashid rover will be the first opportunity to gather data on the behavior of graphene composites within a lunar environment,” says Carlo Iorio, Graphene Flagship Space Champion, from ULB.

Leading up to the Moon mission, a variety of inks containing graphene and related materials, such as conducting graphene, insulating hexagonal boron nitride and graphene oxide, semiconducting molybdenum disulfide, prepared by the University of Cambridge and ULB were also tested on the MAterials Science Experiment Rocket 15 (MASER 15) mission, successfully launched on the 23rd of November 2022 from the Esrange Space Center in Sweden. This experiment, named ARLES-2 (Advanced Research on Liquid Evaporation in Space) and supported by European and UK space agencies (ESA, UKSA) included contributions from Graphene Flagship Partners University of Cambridge (UK), University of Pisa (Italy) and Trinity College Dublin (Ireland), with many international collaborators, including Aix-Marseille University (France), Technische Universität Darmstadt (Germany), York University (Canada), Université de Liège (Belgium), University of Edinburgh and Loughborough.

This experiment will provide new information about the printing of GMR inks in weightless conditions, contributing to the development of new addictive manufacturing procedures in space such as 3d printing. Such procedures are key for space exploration, during which replacement components are often needed, and could be manufactured from functional inks.

“Our experiments on graphene and related materials deposition in microgravity pave the way addictive manufacturing in space. The study of the interaction of Moon regolith with graphene composites will address some key challenges brought about by the harsh lunar environment,” says Yarjan Abdul Samad, from the Universities of Cambridge and Khalifa, who prepared the samples and coordinated the interactions with the United Arab Emirates.    

“The Graphene Flagship is spearheading the investigation of graphene and related materials (GRMs) for space applications. In November 2022, we had the first member of the Graphene Flagship appointed to the ESA astronaut class. We saw the launch of a sounding rocket to test printing of a variety of GRMs in zero gravity conditions, and the launch of a lunar rover that will test the interaction of graphene—based composites with the Moon surface. Composites, coatings and foams based on GRMs have been at the core of the Graphene Flagship investigations since its beginning. It is thus quite telling that, leading up to the Flagship’s 10th anniversary, these innovative materials are now to be tested on the lunar surface. This is timely, given the ongoing effort to bring astronauts back to the Moon, with the aim of building lunar settlements. When combined with polymers, GRMs can tailor the mechanical, thermal, electrical properties of then host matrices. These pioneering experiments could pave the way for widespread adoption of GRM-enhanced materials for space exploration,” says Andrea Ferrari, Science and Technology Officer and Chair of the Management Panel of the Graphene Flagship. 

Caption: The MASER15 launch Credit: John-Charles Dupin

A pioneering graphene work and a first for the Arab World

A December 11, 2022 news item on Alarabiya news (and on CNN) describes the ‘graphene’ launch which was also marked the Arab World’s first mission to the moon,

The United Arab Emirates’ Rashid Rover – the Arab world’s first mission to the Moon – was launched on Sunday [December 11, 2022], the Mohammed bin Rashid Space Center (MBRSC) announced on its official Twitter account.

The launch came after it was previously postponed for “pre-flight checkouts.”

The launch of a SpaceX Falcon 9 rocket carrying the UAE’s Rashid rover successfully took off from Cape Canaveral, Florida.

The Rashid rover – built by Emirati engineers from the UAE’s Mohammed bin Rashid Space Center (MBRSC) – is to be sent to regions of the Moon unexplored by humans.

What is the Graphene Flagship?

In 2013, the Graphene Flagship was chosen as one of two FET (Future and Emerging Technologies) funding projects (the other being the Human Brain Project) each receiving €1 billion to be paid out over 10 years. In effect, it’s a science funding programme specifically focused on research, development, and commercialization of graphene (a two-dimensional [it has length and width but no depth] material made of carbon atoms).

You can find out more about the flagship and about graphene here.

Quantum Mechanics & Gravity conference (August 15 – 19, 2022) launches Vancouver (Canada)-based Quantum Gravity Institute and more

I received (via email) a July 21, 2022 news release about the launch of a quantum science initiative in Vancouver (BTW, I have more about the Canadian quantum scene later in this post),

World’s top physicists unite to tackle one of Science’s greatest
mysteries


Vancouver-based Quantum Gravity Society leads international quest to
discover Theory of Quantum Gravity

Vancouver, B.C. (July 21, 2022): More than two dozen of the world’s
top physicists, including three Nobel Prize winners, will gather in
Vancouver this August for a Quantum Gravity Conference that will host
the launch a Vancouver-based Quantum Gravity Institute (QGI) and a
new global research collaboration that could significantly advance our
understanding of physics and gravity and profoundly change the world as
we know it.

For roughly 100 years, the world’s understanding of physics has been
based on Albert Einstein’s General Theory of Relativity (GR), which
explored the theory of space, time and gravity, and quantum mechanics
(QM), which focuses on the behaviour of matter and light on the atomic
and subatomic scale. GR has given us a deep understanding of the cosmos,
leading to space travel and technology like atomic clocks, which govern
global GPS systems. QM is responsible for most of the equipment that
runs our world today, including the electronics, lasers, computers, cell
phones, plastics, and other technologies that support modern
transportation, communications, medicine, agriculture, energy systems
and more.

While each theory has led to countless scientific breakthroughs, in many
cases, they are incompatible and seemingly contradictory. Discovering a
unifying connection between these two fundamental theories, the elusive
Theory of Quantum Gravity, could provide the world with a deeper
understanding of time, gravity and matter and how to potentially control
them. It could also lead to new technologies that would affect most
aspects of daily life, including how we communicate, grow food, deliver
health care, transport people and goods, and produce energy.

“Discovering the Theory of Quantum Gravity could lead to the
possibility of time travel, new quantum devices, or even massive new
energy resources that produce clean energy and help us address climate
change,” said Philip Stamp, Professor, Department of Physics and
Astronomy, University of British Columbia, and Visiting Associate in
Theoretical Astrophysics at Caltech [California Institute of Technology]. “The potential long-term ramifications of this discovery are so incredible that life on earth 100
years from now could look as miraculous to us now as today’s
technology would have seemed to people living 100 years ago.”

The new Quantum Gravity Institute and the conference were founded by the
Quantum Gravity Society, which was created in 2022 by a group of
Canadian technology, business and community leaders, and leading
physicists. Among its goals are to advance the science of physics and
facilitate research on the Theory of Quantum Gravity through initiatives
such as the conference and assembling the world’s leading archive of
scientific papers and lectures associated with the attempts to reconcile
these two theories over the past century.

Attending the Quantum Gravity Conference in Vancouver (August 15-19 [2022])
will be two dozen of the world’s top physicists, including Nobel
Laureates Kip Thorne, Jim Peebles and Sir Roger Penrose, as well as
physicists Baron Martin Rees, Markus Aspelmeyer, Viatcheslav Mukhanov
and Paul Steinhardt. On Wednesday, August 17, the conference will be
open to the public, providing them with a once-in-a-lifetime opportunity
to attend keynote addresses from the world’s pre-eminent physicists.
… A noon-hour discussion on the importance of the
research will be delivered by Kip Thorne, the former Feynman Professor
of physics at Caltech. Thorne is well known for his popular books, and
for developing the original idea for the 2014 film “Interstellar.” He
was also crucial to the development of the book “Contact” by Carl Sagan,
which was also made into a motion picture.

“We look forward to welcoming many of the world’s brightest minds to
Vancouver for our first Quantum Gravity Conference,” said Frank
Giustra, CEO Fiore Group and Co-Founder, Quantum Gravity Society. “One
of the goals of our Society will be to establish Vancouver as a
supportive home base for research and facilitate the scientific
collaboration that will be required to unlock this mystery that has
eluded some of the world’s most brilliant physicists for so long.”

“The format is key,” explains Terry Hui, UC Berkley Physics alumnus
and Co-Founder, Quantum Gravity Society [and CEO of Concord Pacific].
“Like the Solvay Conference nearly 100 years ago, the Quantum Gravity
Conference will bring top scientists together in salon-style gatherings. The
relaxed evening format following the conference will reduce barriers and
allow these great minds to freely exchange ideas. I hope this will help accelerate
the solution of this hundred-year bottleneck between theories relatively
soon.”

“As amazing as our journey of scientific discovery has been over the
past century, we still have so much to learn about how the universe
works on a macro, atomic and subatomic level,” added Paul Lee,
Managing Partner, Vanedge Capital, and Co-Founder, Quantum Gravity
Society. “New experiments and observations capable of advancing work
on this scientific challenge are becoming increasingly possible in
today’s physics labs and using new astronomical tools. The Quantum
Gravity Society looks forward to leveraging that growing technical
capacity with joint theory and experimental work that harnesses the
collective expertise of the world’s great physicists.”

About Quantum Gravity Society

Quantum Gravity Society was founded in Vancouver, Canada in 2020 by a
group of Canadian business, technology and community leaders, and
leading international physicists. The Society’s founding members
include Frank Giustra (Fiore Group), Terry Hui (Concord Pacific), Paul
Lee and Moe Kermani (Vanedge Capital) and Markus Frind (Frind Estate
Winery), along with renowned physicists Abhay Ashtekar, Sir Roger
Penrose, Philip Stamp, Bill Unruh and Birgitta Whaley. For more
information, visit Quantum Gravity Society.

About the Quantum Gravity Conference (Vancouver 2022)


The inaugural Quantum Gravity Conference (August 15-19 [2022]) is presented by
Quantum Gravity Society, Fiore Group, Vanedge Capital, Concord Pacific,
The Westin Bayshore, Vancouver and Frind Estate Winery. For conference
information, visit conference.quantumgravityinstitute.ca. To
register to attend the conference, visit Eventbrite.com.

The front page on the Quantum Gravity Society website is identical to the front page for the Quantum Mechanics & Gravity: Marrying Theory & Experiment conference website. It’s probable that will change with time.

This seems to be an in-person event only.

The site for the conference is in an exceptionally pretty location in Coal Harbour and it’s close to Stanley Park (a major tourist attraction),

The Westin Bayshore, Vancouver
1601 Bayshore Drive
Vancouver, BC V6G 2V4
View map

Assuming that most of my readers will be interested in the ‘public’ day, here’s more from the Wednesday, August 17, 2022 registration page on Eventbrite,

Tickets:

  • Corporate Table of 8 all day access – includes VIP Luncheon: $1,100
  • Ticket per person all day access – includes VIP Luncheon: $129
  • Ticket per person all day access (no VIP luncheon): $59
  • Student / Academia Ticket – all day access (no VIP luncheon): $30

Date:

Wednesday, August 17, 2022 @ 9:00 a.m. – 5:15 p.m. (PT)

Schedule:

  • Registration Opens: 8:00 a.m.
  • Morning Program: 9:00 a.m. – 12:30 p.m.
  • VIP Lunch: 12:30 p.m. – 2:30 p.m.
  • Afternoon Program: 2:30 p.m. – 4:20 p.m.
  • Public Discussion / Debate: 4:20 p.m. – 5:15 p.m.

Program:

9:00 a.m. Session 1: Beginning of the Universe

  • Viatcheslav Mukhanov – Theoretical Physicist and Cosmologist, University of Munich
  • Paul Steinhardt – Theoretical Physicist, Princeton University

Session 2: History of the Universe

  • Jim Peebles, 2019 Nobel Laureate, Princeton University
  • Baron Martin Rees – Cosmologist and Astrophysicist, University of Cambridge
  • Sir Roger Penrose, 2020 Nobel Laureate, University of Oxford (via zoom)

12:30 p.m. VIP Lunch Session: Quantum Gravity — Why Should We Care?

  • Kip Thorne – 2017 Nobel Laureate, Executive Producer of blockbuster film “Interstellar”

2:30 p.m. Session 3: What do Experiments Say?

  • Markus Aspelmeyer – Experimental Physicist, Quantum Optics and Optomechanics Leader, University of Vienna
  • Sir Roger Penrose – 2020 Nobel Laureate (via zoom)

Session 4: Time Travel

  • Kip Thorne – 2017 Nobel Laureate, Executive Producer of blockbuster film “Interstellar”

Event Partners

  • Quantum Gravity Society
  • Westin Bayshore
  • Fiore Group
  • Concord Pacific
  • VanEdge Capital
  • Frind Estate Winery

Marketing Partners

  • BC Business Council
  • Greater Vancouver Board of Trade

Please note that Sir Roger Penrose will be present via Zoom but all the others will be there in the room with you.

Given that Kip Thorne won his 2017 Nobel Prize in Physics (with Rainer Weiss and Barry Barish) for work on gravitational waves, it’s surprising there’s no mention of this in the publicity for a conference on quantum gravity. Finding gravitational waves in 2016 was a very big deal (see Josh Fischman’s and Steve Mirsky’s February 11, 2016 interview with Kip Thorne for Scientific American).

Some thoughts on this conference and the Canadian quantum scene

This conference has a fascinating collection of players. Even I recognized some of the names, e.g., Penrose, Rees, Thorne.

The academics were to be expected and every presenter is an academic, often with their own Wikipedia page. Weirdly, there’s no one from the Perimeter Institute Institute for Theoretical Physics or TRIUMF (a national physics laboratory and centre for particle acceleration) or from anywhere else in Canada, which may be due to their academic specialty rather than an attempt to freeze out Canadian physicists. In any event, the conference academics are largely from the US (a lot of them from CalTech and Stanford) and from the UK.

The business people are a bit of a surprise. The BC Business Council and the Greater Vancouver Board of Trade? Frank Giustra who first made his money with gold mines, then with Lionsgate Entertainment, and who continues to make a great deal of money with his equity investment company, Fiore Group? Terry Hui, Chief Executive Office of Concord Pacific, a real estate development company? VanEdge Capital, an early stage venture capital fund? A winery? Missing from this list is D-Wave Systems, Canada’s quantum calling card and local company. While their area of expertise is quantum computing, I’d still expect to see them present as sponsors. *ETA December 6, 2022: I just looked at the conference page again and D-Wave is now listed as a sponsor.*

The academics? These people are not cheap dates (flights, speaker’s fees, a room at the Bayshore, meals). This is a very expensive conference and $129 for lunch and a daypass is likely a heavily subsidized ticket.

Another surprise? No government money/sponsorship. I don’t recall seeing another academic conference held in Canada without any government participation.

Canadian quantum scene

A National Quantum Strategy was first announced in the 2021 Canadian federal budget and reannounced in the 2022 federal budget (see my April 19, 2022 posting for a few more budget details).. Or, you may find this National Quantum Strategy Consultations: What We Heard Report more informative. There’s also a webpage for general information about the National Quantum Strategy.

As evidence of action, the Natural Science and Engineering Research Council of Canada (NSERC) announced new grant programmes made possible by the National Quantum Strategy in a March 15, 2022 news release,

Quantum science and innovation are giving rise to promising advances in communications, computing, materials, sensing, health care, navigation and other key areas. The Government of Canada is committed to helping shape the future of quantum technology by supporting Canada’s quantum sector and establishing leadership in this emerging and transformative domain.

Today [March 15, 2022], the Honourable François-Philippe Champagne, Minister of Innovation, Science and Industry, is announcing an investment of $137.9 million through the Natural Sciences and Engineering Research Council of Canada’s (NSERC) Collaborative Research and Training Experience (CREATE) grants and Alliance grants. These grants are an important next step in advancing the National Quantum Strategy and will reinforce Canada’s research strengths in quantum science while also helping to develop a talent pipeline to support the growth of a strong quantum community.

Quick facts

Budget 2021 committed $360 million to build the foundation for a National Quantum Strategy, enabling the Government of Canada to build on previous investments in the sector to advance the emerging field of quantum technologies. The quantum sector is key to fuelling Canada’s economy, long-term resilience and growth, especially as technologies mature and more sectors harness quantum capabilities.

Development of quantum technologies offers job opportunities in research and science, software and hardware engineering and development, manufacturing, technical support, sales and marketing, business operations and other fields.

The Government of Canada also invested more than $1 billion in quantum research and science from 2009 to 2020—mainly through competitive granting agency programs, including Natural Sciences and Engineering Research Council of Canada programs and the Canada First Research Excellence Fund—to help establish Canada as a global leader in quantum science.

In addition, the government has invested in bringing new quantum technologies to market, including investments through Canada’s regional development agencies, the Strategic Innovation Fund and the National Research Council of Canada’s Industrial Research Assistance Program.

Bank of Canada, cryptocurrency, and quantum computing

My July 25, 2022 posting features a special project, Note: All emphases are mine,

… (from an April 14, 2022 HKA Marketing Communications news release on EurekAlert),

Multiverse Computing, a global leader in quantum computing solutions for the financial industry and beyond with offices in Toronto and Spain, today announced it has completed a proof-of-concept project with the Bank of Canada through which the parties used quantum computing to simulate the adoption of cryptocurrency as a method of payment by non-financial firms.

“We are proud to be a trusted partner of the first G7 central bank to explore modelling of complex networks and cryptocurrencies through the use of quantum computing,” said Sam Mugel, CTO [Chief Technical Officer] at Multiverse Computing. “The results of the simulation are very intriguing and insightful as stakeholders consider further research in the domain. Thanks to the algorithm we developed together with our partners at the Bank of Canada, we have been able to model a complex system reliably and accurately given the current state of quantum computing capabilities.”

Multiverse Computing conducted its innovative work related to applying quantum computing for modelling complex economic interactions in a research project with the Bank of Canada. The project explored quantum computing technology as a way to simulate complex economic behaviour that is otherwise very difficult to simulate using traditional computational techniques.

By implementing this solution using D-Wave’s annealing quantum computer, the simulation was able to tackle financial networks as large as 8-10 players, with up to 2^90 possible network configurations. Note that classical computing approaches cannot solve large networks of practical relevance as a 15-player network requires as many resources as there are atoms in the universe.

Quantum Technologies and the Council of Canadian Academies (CCA)

In a May 26, 2022 blog posting the CCA announced its Expert Panel on Quantum Technologies (they will be issuing a Quantum Technologies report),

The emergence of quantum technologies will impact all sectors of the Canadian economy, presenting significant opportunities but also risks. At the request of the National Research Council of Canada (NRC) and Innovation, Science and Economic Development Canada (ISED), the Council of Canadian Academies (CCA) has formed an Expert Panel to examine the impacts, opportunities, and challenges quantum technologies present for Canadian industry, governments, and Canadians. Raymond Laflamme, O.C., FRSC, Canada Research Chair in Quantum Information and Professor in the Department of Physics and Astronomy at the University of Waterloo, will serve as Chair of the Expert Panel.

“Quantum technologies have the potential to transform computing, sensing, communications, healthcare, navigation and many other areas,” said Dr. Laflamme. “But a close examination of the risks and vulnerabilities of these technologies is critical, and I look forward to undertaking this crucial work with the panel.”

As Chair, Dr. Laflamme will lead a multidisciplinary group with expertise in quantum technologies, economics, innovation, ethics, and legal and regulatory frameworks. The Panel will answer the following question:

In light of current trends affecting the evolution of quantum technologies, what impacts, opportunities and challenges do these present for Canadian industry, governments and Canadians more broadly?

The Expert Panel on Quantum Technologies:

Raymond Laflamme, O.C., FRSC (Chair), Canada Research Chair in Quantum Information; the Mike and Ophelia Lazaridis John von Neumann Chair in Quantum Information; Professor, Department of Physics and Astronomy, University of Waterloo

Sally Daub, Founder and Managing Partner, Pool Global Partners

Shohini Ghose, Professor, Physics and Computer Science, Wilfrid Laurier University; NSERC Chair for Women in Science and Engineering

Paul Gulyas, Senior Innovation Executive, IBM Canada

Mark W. Johnson, Senior Vice-President, Quantum Technologies and Systems Products, D-Wave Systems

Elham Kashefi, Professor of Quantum Computing, School of Informatics, University of Edinburgh; Directeur de recherche au CNRS, LIP6 Sorbonne Université

Mauritz Kop, Fellow and Visiting Scholar, Stanford Law School, Stanford University

Dominic Martin, Professor, Département d’organisation et de ressources humaines, École des sciences de la gestion, Université du Québec à Montréal

Darius Ornston, Associate Professor, Munk School of Global Affairs and Public Policy, University of Toronto

Barry Sanders, FRSC, Director, Institute for Quantum Science and Technology, University of Calgary

Eric Santor, Advisor to the Governor, Bank of Canada

Christian Sarra-Bournet, Quantum Strategy Director and Executive Director, Institut quantique, Université de Sherbrooke

Stephanie Simmons, Associate Professor, Canada Research Chair in Quantum Nanoelectronics, and CIFAR Quantum Information Science Fellow, Department of Physics, Simon Fraser University

Jacqueline Walsh, Instructor; Director, initio Technology & Innovation Law Clinic, Dalhousie University

You’ll note that both the Bank of Canada and D-Wave Systems are represented on this expert panel.

The CCA Quantum Technologies report (in progress) page can be found here.

Does it mean anything?

Since I only skim the top layer of information (disparagingly described as ‘high level’ by the technology types I used to work with), all I can say is there’s a remarkable level of interest from various groups who are self-organizing. (The interest is international as well. I found the International Society for Quantum Gravity [ISQG], which had its first meeting in 2021.)

I don’t know what the purpose is other than it seems the Canadian focus seems to be on money. The board of trade and business council have no interest in primary research and the federal government’s national quantum strategy is part of Innovation, Science and Economic Development (ISED) Canada’s mandate. You’ll notice ‘science’ is sandwiched between ‘innovation’, which is often code for business, and economic development.

The Bank of Canada’s monetary interests are quite obvious.

The Perimeter Institute mentioned earlier was founded by Mike Lazaridis (from his Wikipedia entry) Note: Links have been removed,

… a Canadian businessman [emphasis mine], investor in quantum computing technologies, and founder of BlackBerry, which created and manufactured the BlackBerry wireless handheld device. With an estimated net worth of US$800 million (as of June 2011), Lazaridis was ranked by Forbes as the 17th wealthiest Canadian and 651st in the world.[4]

In 2000, Lazaridis founded and donated more than $170 million to the Perimeter Institute for Theoretical Physics.[11][12] He and his wife Ophelia founded and donated more than $100 million to the Institute for Quantum Computing at the University of Waterloo in 2002.[8]

That Institute for Quantum Computing? There’s an interesting connection. Raymond Laflamme, the chair for the CCA expert panel, was its director for a number of years and he’s closely affiliated with the Perimeter Institute. (I’m not suggesting anything nefarious or dodgy. It’s a small community in Canada and relationships tend to be tightly interlaced.) I’m surprised he’s not part of the quantum mechanics and gravity conference but that could have something to do with scheduling.

One last interesting bit about Laflamme, from his Wikipedia entry, Note: Links have been removed)

As Stephen Hawking’s PhD student, he first became famous for convincing Hawking that time does not reverse in a contracting universe, along with Don Page. Hawking told the story of how this happened in his famous book A Brief History of Time in the chapter The Arrow of Time.[3] Later on Laflamme made a name for himself in quantum computing and quantum information theory, which is what he is famous for today.

Getting back to the Quantum Mechanics & Gravity: Marrying Theory & Experiment, the public day looks pretty interesting and when is the next time you’ll have a chance to hobnob with all those Nobel Laureates?

Events: COVID-19 Collages and colour, Summer Solstice Celebration of Star Knowledge—Africa and Rapanui (Easter Island), and Tools for Catching Clouds (Biennale Architettura 2021)

I have three events, two of them taking place in Canada on June 9, and June 22 2021 respectively and the third takes place in Venice, Italy.

Covid19 Collage Project on June 9, 2021

A June 7, 2019 Art/Sci Salon announcement (received via email) included this image to illustrate Ilene Sova’s COVID collages,

Pink Ruffle Credit: Ilene Sova

Here’s more from the Colour Research Society of Canada’s (CRSC) Kaleidoscope Lecture: Covid19 Collage Project by OCAD Professor Ilene Sova event page,

In this unique colour-focused artist talk, Sova will explore her Covid19 Collage Project created in direct response to the pandemic. She will take the audience through an analysis of how she utilizes the precise symbolic and aesthetic qualities of colour-choice to reflect her psychological response to our current times and amplify the intent in her artist statement: ‘Former eyes have been replaced, and the curtain pulled back on the inequities that we didn’t fully see before. Newsfeeds are full of surreal deaths and devastating condolences. Different eyes; metallic and shiny. Eyes that no longer know how to ‘look to our future” for hope and possibilities. Our Instagram lives and our vitriolic materialism now laid bare. We are left to self-reflect, face ourselves, slow down, and toss and turn at night with vivid crackling dreams alive with messages screaming from our subconscious. We thought we were separate from nature, but now we know we are one. Sequestered in our homes, our minds begin to change, fracture with confusion. We float in a sea of unknowns, covering our faces with psychological and real masks. In a sparkly shiny isolated dreamy space; how will we prophesize our new future and manifest in a new uncertain one?

Bio: Ilene Sova holds the position of Ada Slaight Chair of Contemporary Drawing and Painting in the Faculty of Art at Ontario College of Art and Design University [OCAD University]. She identifies as Mixed Race, with a white settler, Afro-Caribbean, and Black Seminole ancestry. She is also an artist who lives with the disability of Epilepsy. As such, she passionately identifies with the tenets of intersectional feminism and has dedicated her creative career to art and activism. Ilene Sova is also the founder of the Feminist Art Collective and Blank Canvases, an in-school creative arts programme for elementary school students. She holds an Honours BFA from the University of Ottawa in Painting and an MFA in Painting and Drawing from the University of Windsor. With extensive solo and group exhibitions in Canada and abroad, Sova’s work has most notably been shown at Museum of Canadian Contemporary Art, the Department of Canadian Heritage, and Mutuo Centro de Arte in Barcelona. Sova’s artwork has been featured internationally in the Journal of Psychology and Counselling, the Nigerian Arts Journal, Tabula and the Italian feminist journal, Woman’O’Clock. In her academic career, Sova has been invited to speak on diversity and equity in arts curriculum at the Art Gallery of Ontario, Pratt University and the Association of Independent Colleges of Art and Design conference in Los Angeles. A passionate public speaker, Sova was chosen to speak at the first TEDx Women event in Toronto, and Southern University New York where she gave an all University Lecture on Art and Social Change. Additionally, Sova was invited to deliver the Arthur C. Danto Memorial Keynote Lecture at the 76th Annual Meeting of the American Society for Aesthetics (ASA). Sova’s exhibitions and advocacy in education have been featured on Global Television, CBC Radio, the Toronto Star, Canada AM, The Metro, National Post, Canadian Art, and MSN News.

Register here on eventbrite

Date and time

Wed, June 9, 2021

4:00 PM – 5:00 PM PDT

A Zoom link will be emailed to registered participants approximately 1 hour before the talk, and posted on our CRSC webpage.

Summer Solstice Celebration of Star Knowledge—Africa and Rapanui (Easter Island) on June 22, 2021

Ingenium’s* Indigenous Star Knowledge Symposia series was first mentioned here in a September 18, 2020 posting: Casting your eyes upon the night heavens in advance of the Autumnal (Fall) Equinox celebration, the first in the series.

With the Summer Solstice, we have the fourth and, I believe, the last in the series. From the Summer Solstice, Celebration of Star Knowledge from Africa and Rapanui (Easter Island) event page,

June 22, 2021. 3 p.m. Eastern.

Featured Speakers: Edmundo Edwards Eastman (Rapanui) and Jarita Holbrook (African culture)

Welcome from: Anita Tenasco, Kitigan Zibi, Quebec (Algonquin)

Opening Prayer: Wilfred Buck, Manitoba (Ininew)

Moderated by: Yasmin Catricheo, Chile (Mapuche)

Presentation #1: Cosmovision of the Polynesia and Rapanui. 

Featured Speaker: Edmundo Edwards Eastman. Archeoastronomy. President Fundación
Planetario Rapanui

Abstract: Some 3,500 years ago, the ancestors of the Polynesians led the speediest human expansion of the pre-historic world, guided by nothing more than their complex astronomical observations and an understanding of natural signs. This knowledge, coupled with tremendous navigational skills and human ingenuity, allowed the Polynesians to explore the vast Pacific Ocean and develop highly sophisticated cultures on thousands of different islands.  

Bio: Edmundo’s passion for archaeology started when he was 12 years old and discovered a pre-Incan site in northern Chile, yet it was after visiting Rapa Nui in 1957, that he became enthralled by Rapanui culture and returned to the island in 1960 with archaeologist William Mulloy.  Edmundo has lived and worked in Polynesia ever since. In 1977 he co-founded the Centro de Estudios de Isla de Pascua where he carried out archaeological and ethnographic studies for the University of Chile until 1985. He then left for Tahiti, conducting archaeological surveys and leading restoration work in the Society, Marquesas, and Austral Islands until he returned to Rapa Nui in 1994. Edmundo has since then devoted himself to the scientific study and preservation of the archaeology and culture of the Pacific islands.  He is the co-founder of the Pacific Islands Research Institute (PIRI) and co-owner of Archaeological Travel Service (ATS). Edmundo is an active member of the Explorers Club and in 2011 he was honored with the Lowell Thomas Award for his exceptional contribution to human knowledge through his valuable research and discoveries in Polynesia, and in 2016 he received the Citation of Merit.

Presentation #2: Celestial Africa

Featured Speaker: Jarita Holbrook

Abstract: The continent of Africa is large and has thousands of ethnic groups living in over 50 countries. Though home to some of the biggest astronomical telescopes in the world, there remains the perception that Africans have little awareness of the celestial realm. In reality, African indigenous astronomy is rich with many cultural connections to the sky as well as many practical uses of the sky. Holbrook will share some of the African legacy of rich skylore, artistic works, and practices connected to the sky.

Bio: Jarita Holbrook is a Marie Skłowdowska Curie Fellow in Science, Technology & Innovation Studies at the University of Edinburgh. Holbrook has successfully navigated the physical science and the social sciences. Upon moving to South Africa in 2013 to the Physics department at the University of the Western Cape, Holbrook was engaged in indigenous astronomy, studying the sociocultural aspects of astrophysics education in South Africa, and making a film about the social issues connected to building the Square Kilometre Array radio telescope. Using interview based inquiry, Holbrook researches the practices of inclusion and exclusion through analyzing socioeconomic class, gender, and ethnicity among database-driven astrophysics collaborations. Holbrook’s current project, ASTROMOVES, explores these in the context of career decision making among astrophysicists.

Panellists:

Anita Tenasco is an Anishinabeg from Kitigan Zibi. She has a Bachelor’s degree in history and teaching from the University of Ottawa, as well as a First Nations leadership certificate from Saint Paul’s University, in Ottawa. She has also taken courses in public administration at ENAP (The University of Public Administration). In Kitigan Zibi, she has held various positions in the field of education and, since 2005, is director of education in her community.

Anita was an active participant in the Honouring Our Ancestors project, in which the Anishinabeg Nation of Kitigan Zibi, under Gilbert Whiteduck’s direction, was successful in the restitution of the remains of ancestors conserved at the Canadian Museum of History, in Gatineau. Anita also participated in the organizing of a conference on repatriation, in Kitigan Zibi, in 2005. She plays an important role in this research project.

http://nikanishk.ca/en/blog/project-participants/anita-tenasco-2/

Wilfred Buck is a member of the Opaskwayak Cree Nation. He obtained his B.Ed. & Post Bacc. from the University of Manitoba.

As an educator Wilfred has had the opportunity and good fortune to travel to South and Central America as well as Europe and met, shared and listened to Indigenous people from all over the world.

He is a husband, father of four, son, uncle, brother, nephew, story-teller, mad scientist, teacher, singer, pipe-carrier, sweat lodge keeper, old person and sun dance leader. Researching Ininew star stories Wilfred found a host of information which had to be interpreted and analyzed to identify if the stories were referring to the stars. The journey began… The easiest way to go about doing this, he was told, was to look up. 

“The greatest teaching that was ever given to me, other than my wife and children, is the ability to see the humor in the world”…Wilfred Buck

https://acakwuskwun.com/

Yasmin Catricheo is the STEM Education Scholar at AUI’s Office of Education and Public Engagement. She is a physics educator from Chile, and of Mapuche origin. Yasmin is passionate about the teaching of science and more recently has focused in the area of astronomy and STEM. In her professional training she has taken a range of courses in science and science education, and researched the benefits of scientific argumentation in the physics classroom, earning a master’s degree in education from the University of Bío-Bío. Yasmín is also a member of the indigenous group “Mapu Trafun”, and she works closely with the Mapuche community to recover the culture and communicate the message of the Mapuche Worldview. In 2018 Yasmín was selected as the Chilean representative for Astronomy in Chile Educator Ambassador Program (ACEAP) founded by NSF.

Associated Universities Inc.

Register for the Webinar

Note: You can also find the information on Ingenium’s French language event page: Solstice d’été : une célébration des connaissances stellaires de l’Afrique et de Rapa Nui (l’île de Pâques).

*Ingenium is the name for Canada’s Museums of Science and Innovation, which acts as an umbrella organization for the Canada Agriculture and Food Museum, the Canada Aviation and Space Museum, and the Canada Science and Technology Museum.

Tools for Catching Clouds at Venice’s Biennale Architettura 2021

This information comes from a June 8, 2021 email received from the artist himself, Lanfranco Aceti,

Tools for Catching Clouds is a new series of works of art by Lanfranco Aceti. They are a segment of Preferring Sinking to Surrender — the artist’s installation at the Venice Architecture Biennale, 2021. The installation is comprised of drawings, sculptures, paintings, videos, performances, and a vegetable garden. 

Curated by Alessandro Melis for the Italian Pavilion, Preferring Sinking to Surrender is a progression and accumulation of works of art that will be developed throughout the duration of the Venice Architecture Biennale, from May 21, 2021, to November 21, 2021. 

The artist reimagines the future in matriarchal terms and bypasses social upheavals and legacies of environmental disasters through a series of aesthetic approaches that navigate melancholia, anger, and hope. The works of art retrace the legacies of the past — back to the Italic tribes that populated the Apennines before the founding of Rome and the arrival of Greeks in southern Italy.  

The worship of the Magna Mater — or the Great Black Mediterranean Mother — by the Italic tribes is a necessary rediscovery to understand the resilience of matriarchy and its values of acceptance and inclusion within societies that have become patriarchal in nature and, de facto, hierarchical and exclusionary. Nevertheless, these values resist and persist, and have empowered entire generations who were considered ‘outsiders’ and who have found, in the embrace of the ‘Mamma Schiavona’ (another name for the Magna Mater), their strength, networks of solidarity, and empowerment. 

Aceti’s research in gender issues and alternative structures to patriarchy, developed during a one year affiliation at Art, Culture and Technology (ACT) @ MIT, inspired a continued analysis of pre-Roman matriarchal societies. This led to the conception of Preferring Sinking to Surrender as an alternative space and narrative to current capitalistic cultural frameworks. 

“I have to say that it is a pleasure working with Alessandro Melis,” said Aceti. “Not every curator is fond of process based art. For me it is particularly rewarding to have found a curator that is both empowering and supportive.” 

For more information and images of Tools for Catching Clouds, click here

About the Artist

Lanfranco Aceti is known for his extensive career as artist, curator, and academic. He has exhibited numerous personal projects including Car Park, a public performance in the UK at the John Hansard Gallery; Who The People?, an installation artwork acquired in its entirety by the Chetham’s Library and Museum in Manchester; Sowing and Reaping, installation artworks acquired in their entirety by the National Museum of Contemporary Art of Cyprus; Hope Coming On, a site-specific choral performance he designed for the Museum of Fine Arts, Boston and realized in front of Turner’s Slave Ship (Slavers Throwing Overboard the Dead and Dying, Typhoon Coming On); Shimmer, a series of sculptural, photographic, and painting works curated by Irini Papadimitriou (V&A) at the Tobazi Mansion in Hydra; a large choral performance titled Accursed for the Thessaloniki Biennial in Greece; and Knock, Knock, Knocking a public space installation in the Mediterranean Garden Pavilion of the New Sea Waterfront of Thessaloniki. Currently, he is developing a large international project, Preferring Sinking to Surrender for the Venice Architecture Biennale 2021, which includes performances in major cities around the world. 

About The Studium

The Studium is Lanfranco Aceti’s artistic studio. It has partnered with public and private organizations as well as with individuals to realize the artist’s works and to develop fora for the discussion of aesthetic approaches to public space, the role of contemporary art in the social political landscape, and themes of social and environmental justice.

For questions or information and materials, please contact The Studium’s Marketing Director, John Francescutti.

The Venice Architecture Biennale (or Biennale Architettura 2021), from May 21, 2021, to November 21, 2021.

Concerns about Zoom? Call for expressions of interest in “Zoom Obscura,” creative interventions for a data ethics of video conferencing

Have you wondered about Zoom video conferencing and all that data being made available? Perhaps questioned ethical issues in addition to those associated with data security? Is so and you’d like to come up with a creative intervention that delves beyond encryption issues, there’s Zoom Obscura (on the creativeinformatics.org website),

CI [Creative Informatics] researchers Pip Thornton, Chris Elsden and Chris Speed were recently awarded funding from the Human Data Interaction Network (HDI +) Ethics & Data competition. Collaborating with researchers from Durham [Durham University] and KCL [Kings College London], the Zoom Obscura project aims to investigate creative interventions for a data ethics of video conferencing beyond encryption.

The COVID-19 pandemic has gifted video conferencing companies, such as Zoom, with a vast amount of economically valuable and sensitive data such as our facial and voice biometrics, backgrounds and chat scripts. Before the pandemic, this ‘new normal’ would be subject to scrutiny, scepticism and critique. Yet, the urgent need for remote working and socialising left us with little choice but to engage with these potentially exploitative platforms.

While much of the narrative around data security revolves around technological ‘solutions’ such as encryption, we think there are other – more creative – ways to push back against the systems of digital capitalism that continue to encroach on our everyday lives.

As part of this HDI-funded project, we seek artists, hackers and creative technologists who are interested in experimenting with creative methods to join us in a series of online workshops that will explore how to restore some control and agency in how we can be seen and heard in these newly ubiquitous online spaces. Through three half-day workshops held remotely, we will bring artists and technicians together to ideate, prototype, and exhibit various interventions into the rapidly normalising culture of video-calling in ways that do not compromise our privacy and limit the sharing of our data. We invite interventions that begin at any stage of the video-calling process – from analogue obfuscation, to software manipulation or camera trickery.

Selected artists/collectives will receive a £1000 commission to take part and contribute in three workshops, in order to design and produce one or more, individual or collaborative, creative interventions developed from the workshops. These will include both technical support from a creative technologist as well as a curator for dissemination both online and in Edinburgh and London.

If you are an artist / technologist interested in disrupting/subverting the pandemic-inspired digital status quo, please send expressions of interest of no more than 500 words to pip.thornton@ed.ac.uk , andrew.dwyer@bristol.ac.uk, celsden@ed.ac.uk and michael.duggan@kcl.ac.uk by 8th October 2020. We don’t expect fully formed projects (these will come in the workshop sessions), but please indicate any broad ideas and thoughts you have, and highlight how your past and present practice might be a good fit for the project and its aims.

The Zoom Obscura project is in collaboration with Tinderbox Lab in Edinburgh and Hannah Redler-Hawes (independent curator and codirector of the Data as Culture art programme at the Open Data Institute in London). Outputs from the project will be hosted and exhibited via the Data as Culture archive site and at a Creative Informatics event at the University of Edinburgh.

Are folks outside the UK eligible?

I asked Dr. Pip Thornton about eligibility and she kindly noted this in her Sept. 25, 2020 tweet (reply copied from my Twitter feed),

Open to all, but workshop timings may be more amenable to UK working hours. Having said that, we won’t know what the critical mass is until we review all the applications, so please do apply if you’re interested!

Who are the members of the Zoom Obscura project team?

From the Zoom Obscura webpage (on the creativeinformatics.org website),

Dr. Pip Thornton is a post-doctoral research associate in Creative Informatics at the University of Edinburgh, having recently gained her PhD in Geopolitics and Cybersecurity from Royal Holloway, University of London. Her thesis, Language in the Age of Algorithmic Reproduction: A Critique of Linguistic Capitalism, included theoretical, political and artistic critiques of Google’s search and advertising platforms. She has presented in a variety of venues including the Science Museum, the Alan Turing Institute and transmediale. Her work has featured in WIRED UK and New Scientist, and a collection from her {poem}.py intervention has been displayed at Open Data Institute in London. Her Edinburgh Futures Institute (EFI) funded installation Newspeak 2019, shown at the Edinburgh Festival Fringe (2019), was recently awarded an honourable mention in the Surveillance Studies Network biennial art competition (2020) and is shortlisted for the 2020 Lumen Prize for art and technology in the AI category.

Dr. Andrew Dwyer is a research associate  in the University of Bristol’s Cyber Security Group. Andrew gained a DPhil in Cyber Security at the University of Oxford, where he studied and questioned the role of malware – commonly known as computational viruses and worms –  through its analysis, detection, and translation into international politics and its intersection with multiple ecologies. In his doctoral thesis – Malware Ecologies: A Politics of Cybersecurity – he argued for a re-evaluation of the role of computational actors in the production and negotiation of security, and what this means for human-centred notions of weapons and warfare. Previously, Andrew has been a visiting fellow at the German ‘Dynamics of Security’ collaborative research centre based between Philipps-Universität Marburg, Justus-Liebig-Universität Gießen and the Herder Institute, Marburg and is a Research Affiliate at the Centre for Technology and Global Affairs at the University of Oxford. He will soon be starting a 3-year Addison Wheeler research fellowship in the Department of Geography at the Durham University

Dr Chris Elsden is a research associate in Design Informatics at the University of Edinburgh. Chris is primarily working on the AHRC Creative Informatics project., with specific interests in FinTech and livestreaming within the Creative Industries. He is an HCI researcher, with a background in sociology, and expertise in the human experience of a data-driven life. Using and developing innovative design research methods, his work undertakes diverse, qualitative and often speculative engagements with participants to investigate emerging relationships with technology – particularly data-driven tools and financialn technologies. Chris gained his PhD in Computer Science at Open Lab, Newcastle University in 2018, and in 2019 was a recipient of a SIGCHI Outstanding Dissertation Award.

Dr Mike Duggan is a Teaching Fellow in Digital Cultures in the Department of Digital Humanities at Kings College London. He was awarded a PhD in Cultural Geography from Royal Holloway University of London in 2017, which examined everyday digital mapping practices. This project was co-funded by the Ordnance Survey and the EPSRC. He is a member of the Living Maps network, where he is an editor for the ‘navigations’ section and previously curated the seminar series. Mike’s research is broadly interested in the digital and cultural geographies that emerge from the intersections between everyday life and digital technology.

Professor Chris Speed is Chair of Design Informatics at the University of Edinburgh where his research focuses upon the Network Society, Digital Art and Technology, and The Internet of Things. Chris has sustained a critical enquiry into how network technology can engage with the fields of art, design and social experience through a variety of international digital art exhibitions, funded research projects, books journals and conferences. At present Chris is working on funded projects that engage with the social opportunities of crypto-currencies, an internet of toilet roll holders, and a persistent argument that chickens are actually robots.  Chris is co-editor of the journal Ubiquity and co-directs the Design Informatics Research Centre that is home to a combination of researchers working across the fields of interaction design, temporal design, anthropology, software engineering and digital architecture, as well as the PhD, MA/MFA and MSc and Advanced MSc programmes.

David Chatting is a designer and technologist who works in software and hardware to explore the impact of emerging technologies in everyday lives. He is currently a PhD student in the Department of Design at Goldsmiths – University of London, a Visiting Researcher at Newcastle University’s Open Lab and has his own design practice. Previously he was a Senior Researcher at BTs Broadband Applications Research Centre. David has a Masters degree in Design Interactions from the Royal College of Art (2012) and a Bachelors degree in Computer Science from the University of Birmingham (2000). He has published papers and filed patents in the fields of HCI, psychology, tangible interfaces, computer vision and computer graphics.

Hannah Redler Hawes (Data as Culture) is an independent curator and codirector of the Data as Culture art programme at the Open Data Institute in London. Hannah specialises in emerging artistic practice within the fields of art and science and technology, with an interest in participatory process. She has previously developed projects for museums, galleries, corporate contexts, digital space and the public realm including the  Institute of Physics, Tate Modern, The Lowry, Natural History Museum, FACT Liverpool, the Digital Catapult and Science Gallery London, and has provided specialist consultancy services to the Wellcome Collection, Discover South Kensington and the Horniman Museum. Hannah enjoys projects that redraw boundaries between different disciplines. Current research is around addiction, open data, networked culture and new forms of programming beyond the gallery.

Tinderbox Collective : From grass-roots youth work to award-winning music productions, Tinderbox is building a vibrant and eclectic community of young musicians and artists in Scotland. We have a number of programmes that cross over with each other and come together wherever possible.  They are open to children and young people aged 10 – 25, from complete beginners to young professionals and all levels in between. Tinderbox Lab is our digital arts programme and shared studio maker-space in Edinburgh that brings together artists across disciplines with an interest in digital media and interactive technologies. It is a new programme that started development in 2019, leading to projects and events such as Room to Play, a 10-week course for emerging artists led by Yann Seznec; various guest artist talks & workshops; digital arts exhibitions at the V&A Dundee & Edinburgh Festival of Sound; digital/electronics workshops design/development for children & young people; and research included as part of Electronic Visualisation and the Arts (EVA) London 2019 conference.

Jack Nissan (Tinderbox) is the founder and director of the Tinderbox Collective. In 2012/13, Jack took part in a fellowship programmed called International Creative Entrepreneurs and spent several months working with community activists and social enterprises in China, primarily with families and communities on the outskirts of Beijing with an organisation called Hua Dan. Following this, he set up a number of international exchanges and cross-cultural productions that formed the basis for Tinderbox’s Journey of a Thousand Wings programme, a project bringing together artists and community projects from different countries. He is also a co-director and founding member of Hidden Door, a volunteer-run multi-arts festival, and has won a number of awards for his work across creative and social enterprise sectors. He has been invited to take part in several steering committees and advisory roles, including for Creative Scotland’s new cross-cutting theme on Creative Learning and Artworks Scotland’s peer-networks for artists working in participatory settings. Previously, Jack worked as a researcher in psychology and ageing for the multidisciplinary MRC Centre for Cognitive Ageing and Cognitive Epidemiology, specialising in areas of neuropsychology and memory.

Luci Holland (Tinderbox) is a Scottish (Edinburgh-based) composer, sound artist and radio presenter who composes and produces music and audiovisual art for film, games and concert. As a games music composer Luci wrote the original dynamic/responsive music for Blazing Griffin‘s 2018 release Murderous Pursuits, and has composed and arranged for numerous video game music collaborations, such as orchestrating and producing an arrangement of Jessica Curry‘s Disappearing with label Materia Collective’s bespoke cover album Pattern: An Homage to Everybody’s Gone to the Rapture. Currently she has also been composing custom game music tracks for Skyrim mod Lordbound and a variety of other film and game music projects. Luci also builds and designs interactive sonic art installations for festivals and venues (Refraction (Cryptic), CITADEL (Hidden Door)); and in 2019 Luci joined new classical music station Scala Radio to present The Console, a weekly one-hour show dedicated to celebrating great music in games. Luci also works as a musical director and composer with the youth music charity Tinderbox Project on their Orchestra & Digital Arts programmes; classical music organisation Absolute Classics; and occasionally coordinates musical experiments and productions with her music-for-media band Mantra Sound.

Good luck to all who submit an expression of interest and good luck to Dr. Thornton (I see from her bio that she’s been shortlisted for the 2020 Lumen Prize).

Replacing nanotechnology-enabled oil spill solutions with dog fur?

Coincidentally or not, this research from Australia was announced a little more than a month after reports of a major oil spill in the Russian Arctic. A July 10, 2020 news item on phys.org announces a new technology for mopping up oil spills (Note: Links have been removed),

Oil spill disasters on land cause long-term damage for communities and the natural environment, polluting soils and sediments and contaminating groundwater.

Current methods using synthetic sorbent materials can be effective for cleaning up oil spills, but these materials are often expensive and generate large volumes of non-biodegradable plastic wastes. Now the first comparison of natural-origin sorbent materials for land-based oil spills, including peat moss, recycled human hair, and dog fur, shows that sustainable, cheaper and biodegradable options can be developed.

The University of Technology Sydney (UTS) project found that dog fur and human hair products—recycled from salon wastes and dog groomers—can be just as good as synthetic fabrics at cleaning up crude oil spills on hard land surfaces like highway roads, pavement, and sealed concrete floors. Polypropylene, a plastic, is a widely-used fabric used to clean up oil spills in aquatic environments.

A July 9, 2020 Univesity of Technology Sydney press release on EurekAlert completes the story,

“Dog fur in particular was surprisingly good at oil spill clean-up, and felted mats from human hair and fur were very easy to apply and remove from the spills.” lead author of the study, UTS Environmental Scientist Dr Megan Murray, said. Dr Murray investigates environmentally-friendly solutions for contamination and leads The Phyto Lab research group at UTS School of Life Sciences.

“This is a very exciting finding for land managers who respond to spilled oil from trucks, storage tanks, or leaking oil pipelines. All of these land scenarios can be treated effectively with sustainable-origin sorbents,” she said.

The sorbents tested included two commercially-available products, propylene and loose peat moss, as well as sustainable-origin prototypes including felted mats made of dog fur and human hair. Prototype oil-spill sorbent booms filled with dog fur and human hair were also tested. Crude oil was used to replicate an oil spill. The results of the study are published in Environments.

The research team simulated three types of land surfaces; non-porous hard surfaces, semi-porous surfaces, and sand, to recreate common oil-spill scenarios.

“We found that loose peat moss is not as effective at cleaning up oil spills on land compared to dog fur and hair products, and it is not useful at all for sandy environments.” Dr Murray said.

“Based on this research, we recommend peat moss is no longer used for this purpose. Given that peat moss is a limited resource and harvesting it requires degrading wetland ecosystems, we think this is a very important finding.” she said.

The research concluded that, for now, sandy environments like coastal beaches can still benefit from the use of polypropylene sorbents, but further exploration of sustainable-origin sorbents is planned.

The researchers say that future applications from the research include investigating felted mats of sustainable-origin sorbents for river bank stabilisation, [emphases mine] as well as the removal of pollutants from flowing polluted waters, similar to existing membrane technology.

Here’s a link to and a citation for the study,

Decontaminating Terrestrial Oil Spills: A Comparative Assessment of Dog Fur, Human Hair, Peat Moss and Polypropylene Sorbents by Megan L. Murray, Soeren M. Poulsen and Brad R. Murray. Environments 2020, 7(7), 52; DOI: https://doi.org/10.3390/environments7070052 Published: 8 July 2020 (This article belongs to the Special Issue Pollution Prevention/Environmental Sustainability for Industry)

This paper is open access.

As for the Russian oil spill

A June 4, 2020 British Broadcasting Corporation (BBC) news online article outlines the situation regarding the oil spill and the steps being taken to deal with it,

Russia’s President Vladimir Putin has declared a state of emergency after 20,000 tonnes of diesel oil leaked into a river within the Arctic Circle.

The spill happened when a fuel tank at a power plant near the Siberian city of Norilsk collapsed last Friday [May 29, 2020].

The power plant’s director Vyacheslav Starostin has been taken into custody until 31 July, but not yet charged.

The plant is owned by a subsidiary of Norilsk Nickel, which is the world’s leading nickel and palladium producer.

The Russian Investigative Committee (SK) has launched a criminal case over the pollution and alleged negligence, as there was reportedly a two-day delay in informing the Moscow authorities about the spill.

Ground subsidence beneath the fuel storage tanks is believed to have caused the spill. Arctic permafrost has been melting in exceptionally warm weather [more information about the weather towards the end of this posting] for this time of year.

Russian Minister for Emergencies Yevgeny Zinichev told Mr Putin that the Norilsk plant had spent two days trying to contain the spill, before alerting his ministry.

The leaked oil drifted some 12km (7.5 miles) from the accident site, turning long stretches of the Ambarnaya river crimson red.

The leaked diesel oil drifted some 12km (7.5 miles) from the site of the accident [downloaded from https://www.bbc.com/news/world-europe-52915807]

Getting back to the June 4, 2020 British Broadcasting Corporation (BBC) news online article,

“Why did government agencies only find out about this two days [May 29, 2020?) after the fact?” he asked the subsidiary’s chief, Sergei Lipin. “Are we going to learn about emergency situations from social media?”

The region’s governor, Alexander Uss, had earlier told President Putin that he became aware of the oil spill on Sunday [May 31, 2020] after “alarming information appeared in social media”.

The spill has contaminated a 350 sq km (135 sq mile) area, state media report.

The state of emergency means extra forces are going to the area to assist with the clean-up operation.

The accident is believed to be the second largest in modern Russian history in terms of volume, an expert from the World Wildlife Fund, Alexei Knizhnikov, told the AFP [Agence France Presse] news agency.

The incident has prompted stark warnings from environmental groups, who say the scale of the spill and geography of the river mean it will be difficult to clean up.

Greenpeace has compared it to the 1989 Exxon Valdez disaster in Alaska.

Oleg Mitvol, former deputy head of Russia’s environmental watchdog Rosprirodnadzor, said there had “never been such an accident in the Arctic zone”.

He said the clean-up could cost 100bn roubles (£1.2bn; $1.5bn) and take between five and 10 years.

Minister of Natural Resources Dmitry Kobylkin warned against trying to burn off such a vast quantity of fuel oil.

He proposed trying to dilute the oil with reagents. Only the emergencies ministry with military support could deal with the pollution, he said.

Barges with booms could not contain the slick because the Ambarnaya river was too shallow, he warned.

He suggested pumping the oil on to the adjacent tundra, although President Putin added: “The soil there is probably saturated [with oil] already.”

An update of the situation can be found in a July 8, 2020 Canadian Broadcasting Corporation (CBC) article (issued by Thomson Reuters),

Russia’s environmental watchdog has asked a power subsidiary of Russian mining giant Norilsk Nickel to pay almost 148 billion rubles, or $2.8 billion Cdn, in damages over an Arctic fuel spill in Siberia.

Rosprirodnadzor, the Federal Service for Supervision of Use of Natural Resources, said in a statement on Monday [July 8, 2020] that it had already sent a request for “voluntary compensation” to the subsidiary, NTEK, after calculating the damage caused by the May 29 [2020] fuel spill.

Norilsk Nickel’s Moscow-listed shares fell by 3 per cent after the watchdog’s statement.

A fuel tank at the power plant lost pressure and released 21,000 tonnes of diesel into rivers and subsoil near the city of Norilsk, 2,900 kilometres northeast of Moscow. Russian President Vladimir Putin subsequently declared a state of emergency in the region, and investigators detained three staff at the power plant.

Norilsk, a remote city of 180,000 people situated 300 kilometres inside the Arctic Circle, is built around Norilsk Nickel, the world’s leading nickel and palladium producer, and has a reputation for its pollution.

Rosprirodnadzor said the damages included the cost for nearby water bodies, estimated at 147.05 billion rubles, $2.8 billion Cdn, and for subsoil, estimated at 738.62 million roubles, $14 million Cdn.

I can’t find any August 2020 updates for the oil spill situation in Russia. (Note: There is now an oil spill in a ecologically sensitive region near Mauritius; see August 13, 2020 news item on CBC news online website.)

Exceptionally warm weather

The oil spill isn’t the only problem in the Arctic.Here’s more from a June 23, 2020 article by Matt Simon for Wired magazine (Note: A link has been removed),

On Saturday [June 20, 2020], the residents of Verkhoyansk, Russia, marked the first day of summer with 100 degree Fahrenheit temperatures. Not that they could enjoy it, really, as Verkhoyansk is in Siberia, hundreds of miles from the nearest beach. That’s much, much hotter than towns inside the Arctic Circle usually get. That 100 degrees appears to be a record, well above the average June high temperature of 68 degrees. Yet it’s likely the people of Verkhoyansk will see that record broken again in their lifetimes: The Arctic is warming twice as fast as the rest of the planet—if not faster—creating ecological chaos for the plants and animals that populate the north.

“The events over the weekend—in the last few weeks, really—with the heatwave in Siberia, all are unprecedented in terms of the magnitude of the extremes in temperature,” says Sophie Wilkinson, a wildfire scientist at McMaster University who studies northern peat fires, which themselves have grown unusually frequent in recent years as temperatures climb.

The Arctic’s extreme warming, known as Arctic amplification or polar amplification, may be due to three factors. One, the region’s reflectivity, or albedo—how much light it bounces back into space—is changing as the world warms. “What we’ve been seeing over the last 30 years is some relatively dramatic declines in sea ice in the summertime,” says University of Edinburgh global change ecologist Isla Myers-Smith, who studies the Arctic.

Since ice is white, it reflects the sun’s energy, something you’re already probably familiar with when it comes to staying cool in the summer. If you had to pick the color of T-shirt to wear when going hiking on a hot day, she says, “most of us would pick the white T-shirt, because that’s going to reflect the sun’s heat off of our back.” Similarly, Myers-Smith says, “If the sea ice melts in the Arctic, that will remove that white surface off of the ocean, and what will be exposed is this darker ocean surface that will absorb more of the sun’s heat.”

If you’re interested in the environmental consequences of the warming of the Arctic, this is a very good article.

Finishing up, I wish the clean-up crews (in Russia and near Mauritius) all the best as they work in the midst of a pandemic, as well as, an environmental disaster (both the oil spill and the warming of the Arctic).

Blockchain made physical: BlocKit

Caption: Parts of BlocKit Credit: Irni Khairuddin

I’m always on the lookout for something that helps make blockchain and cryptocurrency more understandable. (For the uninitiated or anyone like me who needed to refresh their memories, I have links to good essays on the topic further down in this posting.)

A July 10, 2019 news item on ScienceDaily announces a new approach to understanding blockchain technology,

A kit made from everyday objects is bringing the blockchain into the physical world.

The ‘BlocKit’, which includes items such as plastic tubs, clay discs, padlocks, envelopes, sticky notes and battery-powered candles, is aimed to help people understand how digital blockchains work and can also be used by innovators designing new systems and services around blockchain.

A team of computer scientists from Lancaster University, the University of Edinburgh in the UK, and the Universiti Teknologi MARA, in Malaysia, created the prototype BlocKit because blockchain — the decentralised digital infrastructure that is used to organise the cryptocurrency Bitcoin and holds promise to revolutionise many other sectors from finance, supply-chain and healthcare — is so difficult for people to comprehend.

A July 10, 2019 Lancaster University press release (also on EurekAlert), which originated the news item, expands on the theme,

“Despite growing interest in its potential, the blockchain is so novel, disruptive and complex, it is hard for most people to understand how these systems work,” said Professor Corina Sas of Lancaster University’s School of Computing and Communications. “We have created a prototype kit consisting of physical objects that fulfil the roles of different parts of the blockchain. The kit really helps people visualise the different component parts of blockchain, and how they all interact.

“Having tangible physical objects, such as a transparent plastic box for a Bitcoin wallet, clay discs for Bitcoins, padlocks for passwords and candles representing miners’ computational power, makes thinking around processes and systems much easier to comprehend.”

The BlocKit consisted of physical items that represented 11 key aspects of blockchain infrastructure and it was used to explore key characteristics of blockchain, such as trust – an important challenge for Bitcoin users. The kit was evaluated as part of a study involving 15 experienced Bitcoin users.

“We received very positive feedback from the people who used the kit in our study and, interestingly, we found that the BlocKit can also be used by designers looking to develop new services based around blockchain – such as managing patients’ health records for example.”

I will be providing a link to and a citation for the paper but first, I’m excerpting a few bits,

We report on a workshop with 15 bitcoin experts, [emphasis mine] 12 males, 3 females, (mean age 29, range 21-39). All participants had at least 2 years of engaging in bitcoin transactions: 9 had between 2 and 3 years, 4 had between 4 and 5 years, 2had more than 6 years. All participants have at least graduate education, i.e., 6 BSc, 7 MScs, and 2 Ph.D. Participants were recruited through the mailing lists of two universities,and through a local Bitcoins meetup group. [p. 3]

A striking finding was the overwhelmingly positive experience supported by BlocKit. Findings show that 10 participants deeply enjoyed physically touching [emphasis mine] its objects and enacting their movement in space while talking about blockchain processes: “there is going to be other transactions from other people essentially, so let’s put a few bitcoins in that box. I love this stuff, this is amazing” [P12]. Participants suggested that BlocKit could be a valuable tool for learning about blockchain: “I think this all makes sense and would be fine to explain to the novices. It is cool, this is really an interesting kit”[P7]. Other participants suggested leveraging gamification principles for learning about blockchain: “It’s almost like you could turn this into some kind of cool game like a monopoly”[P5] [p. 5]

A significant finding is the value of the kit in supporting experts to materialize and reflect on their understanding of blockchain infrastructure and its inner working. We argue that through its materiality, the kit allows bringing the mental models into question, which in turn helps experts confirm their understandings, develop more nuanced understandings, or even revise some previously held, less accurate assumptions. [emphasis mine]

Even experts are still learning about bitcoin and blockchain according to this research sample. it’s also interesting to note that the workshop participants enjoyed the physicality. I don’t see too many mentions of it in my wanderings but I can’t help wondering if all this digitization is going to leave people starved for touch.

Getting back to blockchain, here’s the link and citation I promised,

BlocKit: A Physical Kit for Materializing and Designing for Blockchain Infrastructure by Irni Eliana Khairuddin, Corina Sas, and Chris Speed.presented at Designing Interactive Systems (DIS) 2019
ACM International Conference Series [downloaded from https://eprints.lancs.ac.uk/id/eprint/132467/1/Design_Kit_DIS_28.pdf]

This paper is open access, as for BlocKit, it exists only as a prototype according to the July 10, 2019 Lancaster University press release.

Introductory essays for blockchain and cryptocurrency

Here are two of my favourites. First, there’s this February 6, 2018 essay (part ii of a series) by Tim Schneider on artnet.com explaining it all by using the art world and art market as examples,

… the fraught relationship between art and value lies at the molten core of several pieces made using blockchain technology. Part one of this series addressed how, in theory, the blockchain strengthens the markets for new media by introducing the concept of digital scarcity. This innovation means that works as simple as an “original” JPG or GIF could be made as rare as Francis Bacon paintings. (This fact leads to a host of business implications that will be covered in Part III.

However, a handful of forward-looking artists is using the blockchain to do more than reset the market’s perception of supply and demand. The technology, their work proves, is more than new software—it’s also a new medium.

The description of how artists using blockchain as a medium provides some of the best descriptions of cryptocurrency and blockchain that I’ve been able to find.

The other essay, a January 5, 2018 article for Slate.com by Joshua Oliver, provides some detail I haven’t seen anywhere else (Note: A link has been removed),

Already, blockchain has been hailed as likely to revolutionize … well … everything. Banks, health care, voting, supply chains, fantasy football, Airbnb, coffee: Nothing is beyond the hypothetical reach of blockchain as a revolutionary force. These predictions are easy to sell because blockchain is still little-understood. If you don’t quite know what blockchain is, it’s easier to imagine that it is whatever you want it to be. But before we can begin to search for the real potential amid the mass of blockchain conjecture and hype, we need to clear up what exactly we mean when we say blockchain.

One cause of confusion is the phrase the blockchain, which makes it sound like blockchain is one specific thing. In reality, the word blockchain is commonly used to describe two broad types of computer systems. [emphases mine] Both use similar underlying protocols, but they have other important differences. Bitcoin represents one approach to using blockchain, one wedded to principles of radical decentralization. The second approach—pioneered by more business-minded players—puts blockchain to use without adopting bitcoin’s revolutionary, decentralized governance. Both of these designs are short-handed as blockchains, so it’s easy to miss the crucial differences. Without grasping these differences, it’s hard to understand where we are today in the development of this promising technology, which blockchain ventures are worth your attention, and what might happen next.

That’s all I’ve got for now.

What helps you may hurt you (titanium dioxide nanoparticles and orthopedic implants)

From a Sept. 16, 2017 news item on Nanotechnology Now,

Researchers from the Mayo Clinic have proposed that negative cellular responses to titanium-based nanoparticles released from metal implants interfere in bone formation and resorption at the site of repair, resulting in implant loosening and joint pain. [emphasis mine]Their review of recent scientific evidence and call for further research to characterize the biological, physical, and chemical interactions between titanium dioxide nanoparticles and bone-forming cells is published in BioResearch Open Access, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers. The article is available free on theBioResearch Open Access website.

A Sept. 14, 2017 Mary Anne Liebert (Publishing) news release, which originated the news item,  mentions the authors,

Jie Yao, Eric Lewallen, PhD, David Lewallen, MD, Andre van Wijnen, PhD, and colleagues from the Mayo Clinic, Rochester, MN and Second Affiliated Hospital of Soochow University, China, coauthored the article entitled “Local Cellular Responses to Titanium Dioxide from Orthopedic Implants The authors examined the results of recently published studies of titanium-based implants, focusing on the direct and indirect effects of titanium dioxide nanoparticles on the viability and behavior of multiple bone-related cell types. They discuss the impact of particle size, aggregation, structure, and the specific extracellular and intracellular (if taken up by the cells) effects of titanium particle exposure.

“The adverse effects of metallic orthopedic particles generated from implants are of significant clinical interest given the large number of procedures carried out each year. This article reviews our current understanding of the clinical issues and highlights areas for future research,” says BioResearch Open Access Editor Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland.

Before getting to the abstract, here’s a link to and a citation for the paper,

Local Cellular Responses to Titanium Dioxide from Orthopedic Implants by Yao, Jie J.; Lewallen, Eric A.; Trousdale, William H.; Xu, Wei; Thaler, Roman; Salib, Christopher G.; Reina, Nicolas; Abdel, Matthew P.; Lewallen, David G.; and van Wijnenm, Andre J.. BioResearch Open Access. July 2017, 6(1): 94-103. https://doi.org/10.1089/biores.2017.0017 Published July 1, 2017

This paper is open access.

Explaining the link between air pollution and heart disease?

An April 26, 2017 news item on Nanowerk announces research that may explain the link between heart disease and air pollution (Note: A link has been removed),

Tiny particles in air pollution have been associated with cardiovascular disease, which can lead to premature death. But how particles inhaled into the lungs can affect blood vessels and the heart has remained a mystery.

Now, scientists have found evidence in human and animal studies that inhaled nanoparticles can travel from the lungs into the bloodstream, potentially explaining the link between air pollution and cardiovascular disease. Their results appear in the journal ACS Nano (“Inhaled Nanoparticles Accumulate at Sites of Vascular Disease”).

An April 26, 2017 American Chemical Society news release on EurekAlert, which originated the news item,  expands on the theme,

The World Health Organization estimates that in 2012, about 72 percent of premature deaths related to outdoor air pollution were due to ischemic heart disease and strokes. Pulmonary disease, respiratory infections and lung cancer were linked to the other 28 percent. Many scientists have suspected that fine particles travel from the lungs into the bloodstream, but evidence supporting this assumption in humans has been challenging to collect. So Mark Miller and colleagues at the University of Edinburgh in the United Kingdom and the National Institute for Public Health and the Environment in the Netherlands used a selection of specialized techniques to track the fate of inhaled gold nanoparticles.

In the new study, 14 healthy volunteers, 12 surgical patients and several mouse models inhaled gold nanoparticles, which have been safely used in medical imaging and drug delivery. Soon after exposure, the nanoparticles were detected in blood and urine. Importantly, the nanoparticles appeared to preferentially accumulate at inflamed vascular sites, including carotid plaques in patients at risk of a stroke. The findings suggest that nanoparticles can travel from the lungs into the bloodstream and reach susceptible areas of the cardiovascular system where they could possibly increase the likelihood of a heart attack or stroke, the researchers say.

Here’s a link to and a citation for the paper,

Inhaled Nanoparticles Accumulate at Sites of Vascular Disease by Mark R. Miller, Jennifer B. Raftis, Jeremy P. Langrish, Steven G. McLean, Pawitrabhorn Samutrtai, Shea P. Connell, Simon Wilson, Alex T. Vesey, Paul H. B. Fokkens, A. John F. Boere, Petra Krystek, Colin J. Campbell, Patrick W. F. Hadoke, Ken Donaldson, Flemming R. Cassee, David E. Newby, Rodger Duffin, and Nicholas L. Mills. ACS Nano, Article ASAP DOI: 10.1021/acsnano.6b08551 Publication Date (Web): April 26, 2017

Copyright © 2017 American Chemical Society

This paper is behind a paywall.