Tag Archives: University of Guelph

CRISPR/Cas9 as a tool for artists (Art/sci Salon January 2018 events in Toronto, Canada) and an event in Winnipeg, Canada

The Art/Sci Salon in Toronto, Canada is offering a workshop and a panel discussion (I think) on the topic of CRISPR( (clustered regularly interspaced short palindromic repeats)/Cas9.

CRISPR Cas9 Workshop with Marta De Menezes

From its Art/Sci Salon event page (on Eventbrite),

This is a two day intensive workshop on

Jan. 24 5:00-9:00 pm
and
Jan. 25 5:00-9:00 pm

This workshop will address issues pertaining to the uses, ethics, and representations of CRISPR-cas9 genome editing system; and the evolution of bioart as a cultural phenomenon . The workshop will focus on:

1. Scientific strategies and ethical issues related to the modification of organisms through the most advanced technology;

2. Techniques and biological materials to develop and express complex concepts into art objects.

This workshop will introduce knowledge, methods and living material from the life sciences to the participants. The class will apply that novel information to the creation of art. Finally, the key concepts, processes and knowledge from the arts will be discussed and related to scientific research. The studio-­‐lab portion of the course will focus on the mastering and understanding of the CRISPR – Cas9 technology and its revolutionary applications. The unparalleled potential of CRISPR ‐ Cas9 for genome editing will be directly assessed as the participants will use the method to make artworks and generate meaning through such a technique. The participants will be expected to complete one small project by the end of the course. In developing and completing these projects, participants will be asked to present their ideas/work to the instructors and fellow participants. As part of the course, participants are expected to document their work/methodology/process by keeping a record of processes, outcomes, and explorations.

This is a free event. Go here to register.

Do CRISPR monsters dream of synthetic futures?

This second event in Toronto seems to be a panel discussion; here’s more from its Art/Sci Salon event page (on Eventbrite),

The term CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) refers to a range of novel gene editing systems which can be programmed to edit DNA at precise locations. It allows the permanent modification of the genes in cells of living organisms. CRISPR enables novel basic research and promises a wide range of possible applications from biomedicine and agriculture to environmental challenges.

The surprising simplicity of CRISPR and its potentials have led to a wide range of reactions. While some welcome it as a gene editing revolution able to cure diseases that are currently fatal, others urge for a worldwide moratorium, especially when it comes to human germline modifications. The possibility that CRISPR may allow us to intervene in the evolution of organisms has generated particularly divisive thoughts: is gene editing going to cure us all? Or is it opening up a new era of designer babies and new types of privileges measured at the level of genes? Could the relative easiness of the technique allow individuals to modify bodies, identities, sexuality, to create new species and races? will it create new monsters? [emphasis mine] These are all topics that need to be discussed. With this panel/discussion, we wish to address technical, ethical, and creative issues arising from the futuristic scenarios promised by CRISPR.

Our Guests:

Marta De Menezes, Director, Cultivamos Cultura

Dalila Honorato, Assistant Professor, Ionian University

Mark Lipton, Professor, University of Guelph

Date: January 26, 2018

Time: 6:00-8:00 pm

Location: The Fields Institute for Research in Mathematical Sciences
222 College Street, Toronto, ON

Events Facilitators: Roberta Buiani and Stephen Morris (ArtSci Salon) and Nina Czegledy (Leonardo Network)

Bios:

Marta de Menezes is a Portuguese artist (b. Lisbon, 1975) with a degree in Fine Arts by the University in Lisbon, a MSt in History of Art and Visual Culture by the University of Oxford, and a PhD candidate at the University of Leiden. She has been exploring the intersection between Art and Biology, working in research laboratories demonstrating that new biological technologies can be used as new art medium. Her work has been presented internationally in exhibitions, articles and lectures. She is currently the artistic director of Ectopia, an experimental art laboratory in Lisbon, and Director of Cultivamos Cultura in the South of Portugal. http://martademenezes.com

Dalila Honorato, Ph.D., is currently Assistant Professor in Media Aesthetics and Semiotics at the Ionian University in Greece where she is one of the founding members of the Interactive Arts Lab. She is the head of the organizing committee of the conference “Taboo-Transgression-Transcendence in Art & Science” and developer of the studies program concept of the Summer School in Hybrid Arts. She is a guest faculty at the PhD studies program of the Institutum Studiorum Humanitatis in Alma Mater Europaea, Slovenia, and a guest member of the Science Art Philosophy Lab integrated in the Center of Philosophy of Sciences of the University of Lisbon, Portugal. Her research focus is on embodiment in the intersection of performing arts and new media.

Mark Lipton works in the College of Arts; in the School of English and Theatre Studies, and Guelph’s Program in Media Studies. Currently, his work focuses on queering media ecological perspectives of technology’s role in education, with emerging questions about haptics and the body in performance contexts, and political outcomes of neo-liberal economics within Higher Education.

ArtSci Salon thanks the Fields Institute and the Bonham Center for Sexual Diversity Studies (U of T), and the McLuhan Centre for Culture and Technology for their support. We are grateful to the members of DIYBio Toronto and Hacklab for hosting Marta’s workshop.

This series of event is promoted and facilitated as part of FACTT Toronto

LASER – Leonardo Art Science Evening Rendezvous is a project of Leonardo® /ISAST (International Society for the Arts Sciences and Technology)

Go here to click on the Register button.

For anyone who didn’t recognize (or, like me, barely remembers what it means) the title’s reference is to a famous science fiction story by Philip K. Dick. Here’s more from the Do Androids Dream of Electric Sheep? Wikipedia entry (Note: Links have been removed),

Do Androids Dream of Electric Sheep? (retitled Blade Runner: Do Androids Dream of Electric Sheep? in some later printings) is a science fiction novel by American writer Philip K. Dick, first published in 1968. The novel is set in a post-apocalyptic San Francisco, where Earth’s life has been greatly damaged by nuclear global war. Most animal species are endangered or extinct from extreme radiation poisoning, so that owning an animal is now a sign of status and empathy, an attitude encouraged towards animals. The book served as the primary basis for the 1982 film Blade Runner, and many elements and themes from it were used in its 2017 sequel Blade Runner 2049.

The main plot follows Rick Deckard, a bounty hunter who is tasked with “retiring” (i.e. killing) six escaped Nexus-6 model androids, while a secondary plot follows John Isidore, a man of sub-par IQ who aids the fugitive androids. In connection with Deckard’s mission, the novel explores the issue of what it is to be human. Unlike humans, the androids are said to possess no sense of empathy.

I wonder why they didn’t try to reference Orphan Black (its Wikipedia entry)? That television series was all about biotechnology. If not Orphan Black, what about a Frankenstein reference? It’s the 200th anniversary this year (2018) of the publication of the book which is the forerunner to all the cautionary tales that have come after.

Nanotechnology at the University of McGill (Montréal, Canada) and other Canadian universities

On the occasion of the McGill University’s new minor program in nanotechnology, I decided to find other Canadian university nanotechnology programs.

First, here’s more about the McGill program from an Oct. 25, 2016 article by Miguel Principe for The McGill Tribune (Note: Links have been removed),

McGill’s Faculty of Engineering launched a new minor program this year that explores into the world of nanotechnology. It’s a relatively young field that focuses on nanomaterials—materials that have one dimension measuring 100 nanometres or less. …

“Nanomaterials are going to be very prominent in our everyday lives,” Assistant Professor Nathalie Tufenkji, of McGill’s Department of Chemical Engineering, said.  “We’re incorporating these materials into our everyday consumer products […] we’re putting these materials on our skin, […] in our paints, and electronics that we are contacting everyday.”

The new engineering minor program aims to introduce undergraduates to techniques in nanomaterial characterization and detection, as well as nanomaterial synthesis and processing. These concepts will be covered in courses such as Nanoscience and Nanotechnology, Supramolecular Chemistry, and Design and Manufacture of Microdevices.

Tufenkji, along with Professor Peter Grutter in the Department of Physics were instrumental in organizing this program. The minor is interdepartmental and includes courses in physics and engineering.

“Of course there’s a flipside on how do we best develop nanotechnology to […] take advantage of its promise,” Tufenkji said. “One of the questions […] is what are the potential impacts on our health and environment of nanomaterials?”

Tufenkji believes it is important that Canada has scientists and engineers that are educated in emerging scientific concepts and cutting-edge technology. Giving undergraduate students exposure to nanotechnology research early in their studies is a good stepping stone for further investigation into the evolving field.

The most comprehensive list of nanotechnology degree programs in Canada (16 programs) is at Nanowerk (Note: Links have been removed and you may find some repetition),

Carleton University – BSc Chemistry with a concentration in Nanotechnology
This concentration allows students to study atoms and molecules used to create computer chips and other devices that are the size of a few nanometres – thousands of times smaller than current technology permits. Such discoveries will be useful in a number of fields, including aerospace, medicine, and electronics.

Carleton University – BSc Nanoscience
At Carleton, you will examine nanoscience through the disciplines of physical chemistry and electrical engineering to understand the physical, chemical and electronic characteristics of matter in this size regime. The combination of these two areas of study will equip you to fully understand nanoscience in photonic, electronic, energy and communication technologies. The focus of the program will be on materials – their use in electronic devices, their scalability and control of their properties.

McGill University – Bachelor of Engineering, Minor Nanotechnology
Through courses already offered in the Faculties of Science, Engineering, and Medicine, depending on the courses completed, undergraduate students will acquire knowledge in areas related to nanotechnology.

Northern Alberta Institute of Technology – Nanotechnology Systems Diploma Program
The two year program will provide graduates with the skills to operate systems and equipment associated with Canada’s emerging nanotechnology industry and lead to a Diploma in Nanotechnology Systems.

University of Alberta – BSc Computer Engineering with Nanoscale System Design Option
This options provides an introduction to the processes involved in the fabrication of nanoscale integrated circuits and to the computer aided design (CAD) tools necessary for the engineering of large scale system on a chip. By selecting this option, students will learn about fault tolerance in nanoscale systems and gain an understanding of quantum phenomena in systems design.

University of Alberta – BSc Electrical Engineering with Nanoengineering Option
This option provides an introduction to the principles of electronics, electromagnetics and photonics as they apply at the nanoscale level. By selecting this option, students will learn about the process involved in the fabrication of nanoscale structures and become familiar with the computer aided design (CAD) tools necessary for analyzing phenomena at these very high levels of miniaturization.

University of Alberta – BSc Engineering Physics with Nanoengineering Option
The Nanoengineering Option provides broad skills suitable for entry to the nanotechnology professions, combining core Electrical Engineering and Physics courses with additional instruction in biochemistry and chemistry, and specialized instruction in nanoelectronics, nanobioengineering, and nanofabrication.

University of Alberta – BSc Materials Engineering with Nano and Functional Materials Option
Students entering this option will be exposed to the exciting and emerging field of nano and functional materials. Subject areas covered include electronic, optical and magnetic materials, nanomaterials and their applications, nanostructured molecular sieves, nano and functional materials processing and fabrication. Employment opportunities exist in several sectors of Canadian industry, such as microelectronic/optoelectronic device fabrication, MEMS processing and fuel cell development.

University of Calgary – B.Sc. Concentration in Nanoscience
Starting Fall 2008/Winter 2009, students can enroll in the only process learning driven Nanoscience program in North America. Courses offered are a B.Sc. Minor in Nanoscience and a B.Sc. Concentration in Nanoscience.

University of Calgary – B.Sc. Minor in Nanoscience
Starting Fall 2008/Winter 2009, students can enroll in the only process learning driven Nanoscience program in North America. Courses offered are a B.Sc. Minor in Nanoscience and a B.Sc. Concentration in Nanoscience.

University of Guelph – Nanoscience B.Sc. Program
At Guelph we have created a unique approach to nanoscience studies. Fundamental science course are combined with specially designed courses in nanoscience covering material that would previously only be found in graduate programs.

University of Toronto – BASc in Engineering Science (Nanoengineering Option)
This option transcends the traditional boundaries between physics, chemistry, and biology. Starting with a foundation in materials engineering and augmented by research from the leading-edge of nanoengineering, students receive an education that is at the forefront of this constantly evolving area.

University of Waterloo – Bachelor of Applied Science Nanotechnology Engineering
The Nanotechnology Engineering honours degree program is designed to provide a practical education in key areas of nanotechnology, including the fundamental chemistry, physics, and engineering of nanostructures or nanosystems, as well as the theories and techniques used to model, design, fabricate, or characterize them. Great emphasis is placed on training with modern instrumentation techniques as used in the research and development of these emerging technologies.

University of Waterloo – Master of Applied Science Nanotechnology
The interdisciplinary research programs, jointly offered by three departments in the Faculty of Science and four in the Faculty of Engineering, provide students with a stimulating educational environment that spans from basic research through to application. The goal of the collaborative programs is to allow students to gain perspectives on nanotechnology from a wide community of scholars within and outside their disciplines in both course and thesis work. The MASc and MSc degree collaborative programs provide a strong foundation in the emerging areas of nano-science or nano-engineering in preparation for the workforce or for further graduate study and research leading to a doctoral degree.

University of Waterloo – Master of Science Nanotechnology
The interdisciplinary research programs, jointly offered by three departments in the Faculty of Science and four in the Faculty of Engineering, provide students with a stimulating educational environment that spans from basic research through to application. The goal of the collaborative programs is to allow students to gain perspectives on nanotechnology from a wide community of scholars within and outside their disciplines in both course and thesis work. The MASc and MSc degree collaborative programs provide a strong foundation in the emerging areas of nano-science or nano-engineering in preparation for the workforce or for further graduate study and research leading to a doctoral degree.

University of Waterloo – Ph.D. Program in Nanotechnology
The objective of the PhD program is to prepare students for careers in academia, industrial R&D and government research labs. Students from Science and Engineering will work side-by-side in world class laboratory facilities namely, the Giga-to-Nano Electronics Lab (G2N), Waterloo Advanced Technology Lab (WatLAB) and the new 225,000 gross sq. ft. Quantum-Nano Center expected to be completed in early 2011.

The Wikipedia entry for Nanotechnology education lists a few Canadian university programs that seem to have been missed, as well as a few previously seen in the Nanowerk list (Note: Links have been removed),

  • University of Alberta – B.Sc in Engineering Physics with Nanoengineering option
  • University of Toronto – B.A.Sc in Engineering Science with Nanoengineering option
  • University of Waterloo – B.A.Sc in Nanotechnology Engineering
    • Waterloo Institute for Nanotechnology -B.Sc, B.A.Sc, master’s, Ph.D, Post Doctorate
  • McMaster University – B.Sc in Engineering Physics with Nanotechnology option
  • University of British Columbia – B.A.Sc in Electrical Engineering with Nanotechnology & Microsystems option
  • Carleton University – B.Sc in Chemistry with Concentration in Nanotechnology
  • University of Calgary – B.Sc Minor in Nanoscience, B.Sc Concentration in Nanoscience
  • University of Guelph – B.Sc in Nanoscience

So, there you have it.

Bob McDonald: How is Canada on the ‘forefront of pushing nanotechnology forward’?

Mr. Quirks & Quarks, also known as the Canadian Broadcasting Corporation’s (CBC) Bob McDonald, host of the science radio programme Quirks & Quarks, published an Oct. 9, 2016 posting on the programme’s CBC blog about the recently awarded 2016 Nobel Prize for Chemistry and Canada’s efforts in the field of nanotechnology (Links have been removed),

The Nobel Prize in Chemistry awarded this week for developments in nanotechnology heralds a new era in science, akin to the discovery of electromagnetic induction 185 years ago. And like electricity, nanotechnology could influence the world in dramatic ways, not even imaginable today.

The world’s tiniest machines

The Nobel Laureates developed molecular machines, which are incredibly tiny devices assembled one molecule at a time, including a working motor, a lifting machine, a micro-muscle, and even a four wheel drive vehicle, all of which can only be seen with the most powerful electron microscopes. While these lab experiments are novel curiosities, the implications are huge, and Canada is on the forefront of pushing this research forward. [emphasis mine]

McDonald never explains how Canadians are pushing nanotechnology research further but there is this (Note: Links have been removed),

Many universities offer degree programs on the subject while organizations such as the National Institute for Nanotechnology at the University of Alberta, and the Waterloo Institute for Nanotechnology at the University of Waterloo in Ontario, are conducting fundamental research on these new novel materials.

Somehow he never mentions any boundary-pushing research. hmmm

To be blunt, it’s very hard to establish Canada’s position in the field since ‘nanotechnolgy research’ as such doesn’t exist here in the way it does in the United States, Korea, Iran, Germany, China, the United Kingdom, Ireland, Austria, and others. It’s not a federally coordinated effort in Canada despite the fact that we have a Canada National Research Council (NRC) National Institute of Nanotechnology (NINT) in Alberta. (There’s very little information about research on the NINT website.) A Government of Canada NanoPortal is poorly maintained and includes information that is seriously out-of-date. One area where Canadians have been influential has been at the international level where we’ve collaborated on a number of OECD (Organization for Economic and Cooperative Development) projects focused on safety (occupational and environmental, in particular) issues.

Canada’s Ingenuity Lab, a nanotechnology project that appeared promising, hasn’t made many research announcements and seems to be a provincial (Alberta) initiative rather than a federal one. In fact, the most activity in the field of nanotechnology research has been at the provincial level with Alberta and Québec in the lead, if financial investment is your primary measure, and Ontario following, then the other provinces trailing from behind. Unfortunately, I’ve never come across any nanotechnology research from the Yukon or other parts North.

With regard to research announcements, the situation changes and you have Québec and Ontario assuming the lead positions with Alberta following. As McDonald noted, the University of Waterloo has a major nanotechnology education programme and the University of Toronto seems to have a very active research focus in that field (Ted Sargent and solar cells and quantum dots) and the University of Guelph is known for its work in agriculture and nanotechnolgy (search this blog using any of the three universities as a search term). In Québec, they’ve made a number of announcements about cutting edge research. You can search this blog for the names Sylvain Martel, Federico Rosei, and Claude Ostiguy (who seems to work primarily in French), amongst others. CelluForce, based in Quebec, and once  a leader (not sure about the situation these days) in the production of cellulose nanocrystals (CNC). One side comment, CNC was first developed at the University of British Columbia, however, Québec showed more support (provincial funding) and interest and the bulk of that research effort moved.

There’s one more shout out and that’s for Blue Goose Biorefineries in the province of Saskatchewan, which sells CNC and offers services to help companies  research applications for the material.

One other significant area of interest comes to mind, the graphite mines in Québec and Ontario which supply graphite flakes used to produce graphene, a material that is supposed to revolutionize electronics, in particular.

There are other research efforts and laboratories in Canada but these are the institutions and researchers with which I’m most familiar after more than eight years of blogging about Canadian nanotechnology. That said, if I’ve missed any significant, please do let me know in the comments section of this blog.

Hexanal and preventing (or diminishing) fruit spoilage

More mangoes thanks to an Indian-Sri Lankan-Canadian nanotechnologyresearch project is a Feb. 9, 2015 posting where I highlighted (not for the first time) a three country research project utilizing hexanal in boxes for fruit (mango) storage,

I’ve been wondering what happened since I posted about this ‘mango’ project some years ago (my June 21, 2012 posting and my Nov. 1, 2012 posting) so, it’s nice to get an update from this Fresh Fruit Portal Feb. 4, 2015 posting,

Developed by Canadian, Indian and Sri Lankan researchers in a collaborative project funded by the International Development Research Centre (IDRC), the nanotech mango boxes are said to improve the fruit’s resilience and therefore boost quality over long shipping distances.

The project – which also includes the Tamil Nadu Agricultural University, India and the Industrial Technical Institute, Sri Lanka – has tested the use of the bio-compound hexanal, an artificially synthesized version of a natural substance produced by injured plants to reduce post-harvest losses.

In the Feb. 9, 2015 posting I was featuring the project again as it had received new funding,

  • Researchers from the University of Guelph, Canada, Tamil Nadu Agricultural University, India, and the Industrial Technical Institute, Sri Lanka, have shown that a natural compound known as hexanal delays the ripening of mangos. Using nanotechnology, the team will continue to develop hexanal-impregnated packaging and biowax coatings to improve the fruit’s resilience during handling and shipping for use in Asia, Africa, and the Caribbean. It will also expand its research to include other fruit and look at ways to commercialize the technologies.

New funding will allow the research teams to further develop the new technologies and involve partners who can bring them to market to reach greater numbers of small-holder farmers.

A Dec. 29, 2015 article (Life of temperate fruits in orchards extended, thanks to nanotech) in The Hindu newspaper provides an update on the collaboration,

Talking to mediapersons after taking part in a workshop on ‘Enhanced Preservation of Fruits using Nanotechnology Project’ held at the Horticultural College and Research Institute, Periyakulam near here on Monday [Dec. 28, 2015], he [K.S. Subramanian, Professor, Department of Nano Science and Technology, TNAU, Coimbatore] said countries like Sri Lanka, Tanzania, Kenya and West Indies will benefit. Post-harvest loss in African countries was approximately 80 per cent, whereas it was 25 to 30 per cent in India, he said.

With the funds sanctioned by Canadian Department of Foreign Affairs, Trade and Development and International Development Research Centre, Canada, the TN Agricultural University, Coimbatore, involving scientists in University of Guelph, Canada, Industrial Technology Institute, Colombo, Sokoine University of Agriculture, Tanzania, University of Nairobi [Kenya], University of West Indies, Trinidad and Tobago, have jointly developed Hexanal formulation, a nano-emulsion, to minimise post harvest loss and extend shelf life of mango.

Field trials have been carried out successfully in Dharmapuri and Krishnagiri on five varieties – Neelam, Bangalura, Banganapalle, Alphonso and Imam Pasand. Pre-harvest spray of Hexanal formulation retained fruits in the trees for three weeks and three more weeks in storage.

Extending life to six to eight weeks will benefit exporters immensely as they required at least six weeks to take fruits to European and the US market. Existing technologies were sufficient to retain fruits up to four weeks only. Domestic growers too can delay harvest and tap market when in demand.

In a companion Dec. 29, 2015 article (New technologies will enhance income of farmers) for The Hindu, benefits for the Indian agricultural economy were extolled,

Nano technology is an ideal tool to extend the shelf life and delay in ripening mango in trees, but proper bio-safety tests should be done before introducing it to farmers, according to Deputy Director General of ICAR N.K. Krishnakumar.

Inaugurating a workshop on Enhanced Preservation of Fruits using Nanotechnology Project held at the Horticultural College and Research Institute at Periyakulam near here on Monday [Dec. 28, 2015], he said that bio safety test was very important before implementing any nano-technology. Proper adoption of new technologies would certainly enhance the income of farmers, he added.

Demand for organic fruits was very high in foreign countries, he said, adding that Japan and Germany were prepared to buy large quantum of organic pomegranate. Covering fruits in bags would ensure uniform colour and quality, he said.

He appealed to scale down use of chemical pesticides and fertilizers to improve quality and taste. He said dipping mango in water mixed with salt will suffice to control fungus.

Postgraduate and research students should take up a problem faced by farmers and find a solution to it by working in his farm. His thesis could be accepted for offering degree only after getting feedback from that farmer. Such measure would benefit college, students and farmers, Mr. Krishnakumar added.

It’s good to get an update on the project’s progress and, while it’s not clear from the excerpts I have here, they are testing hexanal with on fruit other than mangoes.

University of Guelph (Canada) gets money for new nanotechnology antimicrobial delivery vehicles

It’s usually an agricultural story when I cover nanotechnology happenings at the University of Guelph (Ontario, Canada).  However, this July 10, 2015 news item on Azonano is focused on pharmaceutical,

EastGate Biotech Corp., an emerging pharmaceutical company aimed at utilizing drug delivery innovations in the development of improved novel formulations and alternative dosage forms of existing biologically active molecules, has announced that its research collaborator, the University of Guelph, Department of Molecular and Cellular Biology received a grant from the National Sciences and Engineering Research Council of Canada (NSERC).

A July 7, 2015 Eastgate Biotech news release, which originated the news item, describes the nature of their previous collaboration with the University of Guelph but nothing much about the work being undertaken under the auspices of the latest NSERC grant,

Previously the company announced that its research collaboration with the University of Guelph involved measuring the antimicrobial activity of the company’s natural antibacterial products, Cleanezze™ and Vclean™ (www.nano-essentials.com).   Cleanezze™ is a long acting hand sanitizer that contains 3 different natural antibacterial compounds.  Vclean™ is a natural, non-toxic and highly effective concentrate for the elimination of dangerous germs from surfaces of fruits, vegetables, kitchen tools, etc.  The results of this study demonstrated the effectiveness of these products.

The research team at the University of Guelph led by Principal Investigator, Dr. Cezar Khursigara will continue to study the antimicrobial activity of our products.

“We are pleased with the grant awarded to our collaborators at the University of Guelph”, says Anna Gluskin, EastGate’s CEO. “This support will serve to validate the effectiveness of the company’s natural antibacterial products and provide the competitive benefits for the demanding marketplace looking to combat increases in microbial outbreaks”, continued Ms. Gluskin.

I went to the NSERC website for more information and found a list of 2015 research grant recipients listed by institution, which yielded this likely entry under the University of Guelph (Note: I have not replicated the table formatting of the original entry),

Khursigara, Cezar
Department: Molecular and Cellular Biology – Molecular and Cellular Biology
RGPIN
Probing the molecular interactions and architecture of bacterial cell division proteins
1501
5
$34,000.00

That’s all I can find by way of details. By the way, Eastgate Biotech is a Canadian company headquartered in Toronto, Ontario.

More mangoes thanks to an Indian-Sri Lankan-Canadian nanotechnologyresearch project

I’ve been wondering what happened since I posted about this ‘mango’ project some years ago (my June 21, 2012 posting and my Nov. 1, 2012 posting) so, it’s nice to get an update from this Fresh Fruit Portal Feb. 4, 2015 posting,

Developed by Canadian, Indian and Sri Lankan researchers in a collaborative project funded by the International Development Research Centre (IDRC), the nanotech mango boxes are said to improve the fruit’s resilience and therefore boost quality over long shipping distances.

The project – which also includes the Tamil Nadu Agricultural University, India and the Industrial Technical Institute, Sri Lanka – has tested the use of the bio-compound hexanal, an artificially synthesized version of a natural substance produced by injured plants to reduce post-harvest losses.

The nanotech boxes could be particularly significant for India as a world leader in mango production, as well as Sri Lanka where approximately 90,000 metric tons (MT) are produced annually.

The IDRC report says although South Asian fruit production is globally competitive, the region only meets around half of its demand due to poor processing and preservation facilities. Waste can be as high as 35% and amounts to billions of dollars in annual losses.

Historically, the Indian mango sector has suffered severe post-harvest loses due to the lack of cold chain supply infrastructure across the country, and developing a smart packing system like nanotech boxes could therefore be one way to address such challenges.

“Special boxes have been designed to reduce losses during transport. The boxes are sturdy, and can be stacked without risking damage to the fruit, and this alone can reduce post-harvest losses by 10-15%,” the IDRC report continues.

“In order to further improve the storage life of fruits during transport, the project has made a pioneering attempt to develop ‘nano-matrices’ using banana fibers to regulate the release of hexanal.

I wasn’t able to find much more about the project which ended in August 2014 but there is new work being funded as per a Jan. 23, 2015 IDRC news release,

Canada’s International Development Research Centre (IDRC) and Foreign Affairs, Trade and Development Canada (DFATD) today announced three new projects to be supported under the Canadian International Food Security Research Fund (CIFSRF). The projects will help prevent livestock diseases and post-harvest fruit losses that affect millions of farmers around the world, and build on the successful research carried out during CIFSRF’s first phase. [emphasis mine]

  • Researchers from the University of Guelph, Canada, Tamil Nadu Agricultural University, India, and the Industrial Technical Institute, Sri Lanka, have shown that a natural compound known as hexanal delays the ripening of mangos. Using nanotechnology, the team will continue to develop hexanal-impregnated packaging and biowax coatings to improve the fruit’s resilience during handling and shipping for use in Asia, Africa, and the Caribbean. It will also expand its research to include other fruit and look at ways to commercialize the technologies.

New funding will allow the research teams to further develop the new technologies and involve partners who can bring them to market to reach greater numbers of small-holder farmers.

It seems this new round of funding will help bring these nanotechnology-enabled products to market.

FOE, nano, and food: part three of three (final guidance)

The first part of this food and nano ‘debate’ started off with the May 22, 2014 news item on Nanowerk announcing the Friends of the Earth (FOE) report ‘Way too little: Our Government’s failure to regulate nanomaterials in food and agriculture‘. Adding energy to FOE’s volley was a Mother Jones article written by Tom Philpott which had Dr. Andrew Maynard (Director of the University of Michigan’s Risk Science Center) replying decisively in an article published both on Nanowerk and on the Conversation.

The second part of this series focused largely on a couple of  research efforts (a June 11, 2014 news item on Nanowerk highlights a Franco-German research project, SolNanoTox) and in the US (a  June 19, 2014 news item on Azonano about research from the University of Arizona focusing on nanoscale additives for dietary supplement drinks) and noted another activist group’s (As You Sow) initiative with Dunkin’ Donuts (a July 11, 2014 article by Sarah Shemkus in a sponsored section in the UK’s Guardian newspaper0).

This final part in the series highlights the US Food and Drug Administration’s (FDA) final guidance document on nanomaterials and food issued some five weeks after the FOE’s report and an essay by a Canadian academic on the topic of nano and food.

A July 9, 2014 news item on Bloomberg BNA sums up the FDA situation,

The Food and Drug Administration June 24 [2014] announced new guidance to provide greater regulatory clarity for industry on the use of nanotechnology in FDA-regulated products, including drugs, devices, cosmetics and food.

In this final guidance, the agency said that nanotechnology “can be used in a broad array of FDA-regulated products, including medical products (e.g., to increase bioavailability of a drug), foods (e.g., to improve food packaging) and cosmetics (e.g., to affect the look and feel of cosmetics).”

Also on the agency website, the FDA said it “does not make a categorical judgment that nanotechnology is inherently safe or harmful. We intend our regulatory approach to be adaptive and flexible and to take into consideration the specific characteristics and the effects of nanomaterials in the particular biological context of each product and its intended use.”

This July 18, 2014 posting by Jeannie Perron, Miriam Guggenheimm and Allan J. Topol of Covington & Burling LLP on the National Law Review blog provides a better summary and additional insight,

On June 24, 2014, the Food and Drug Administration (FDA) released three final guidance documents addressing the agency’s general approach to nanotechnology and its use by the food and cosmetics industries, as well as a draft guidance on the use of nanomaterials in food for animals.

These guidance documents reflect FDA’s understanding of nanomaterials as an emerging technology of major importance with the potential to be used in novel ways across the entire spectrum of FDA- regulated products.

The documents suggest that FDA plans to approach nanotechnology-related issues cautiously, through an evolving regulatory structure that adapts to manufacturers’ changing uses of this technology. FDA has not established regulatory definitions of “nanotechnology,” “nanomaterial,” “nanoscale,” or other related terms. …

The notion of an “evolving regulatory structure” is very appealing in situations with emerging technologies with high levels of uncertainty. It’s surprising that more of the activist groups don’t see an opportunity with this approach. An organization that hasn’t devised a rigid regulatory structure has no investment in defending it. Activist groups can make the same arguments, albeit from a different perspective, about an emerging technology as the companies do and, theoretically, the FDA has become a neutral party with the power to require a company to prove its products’ safety.

You can find the FDA final guidance and other relevant documents here.

Finally, Sylvain Charlebois, associate dean at the College of Business and Economics at the University of Guelph, offers a rather provocative (and not from the perspective you might expect given his credentials) opinion on the topic of ‘nano and food’  in a July 18, 2014 article for TheRecord.com,

Nanotechnology and nanoparticles have been around for quite some time. In fact, consumers have been eating nanoparticles for years without being aware they are in their food.

Some varieties of Dentyne gum and Jell-O, M&M’s, Betty Crocker whipped cream frosting, Kool-Aid, Pop-Tarts, you name it, contain them. Even food packaging, such as plastic containers and beer bottles, have nanoparticles.

While consumers and interest groups alike are registering their concerns about genetically modified organisms, the growing role of nanotechnology in food and agriculture is impressive. When considering the socio-economic and ethical implications of nanotechnology, comparisons to the genetic modification debate are unavoidable.

The big picture is this. For years, capitalism has demonstrated its ability to create wealth while relying on consumers’ willingness to intrinsically trust what is being offered to them. With trans fats, genetically modified organisms and now nanoparticles, our food industry is literally playing with fire. [emphasis mine]

Most consumers may not have the knowledge to fully comprehend the essence of what nanotechnology is or what it can do. However, in an era where data access in almost constant real-time is king, the industry should at least give public education a shot.

In the end and despite their tactics, the activist groups do have a point. The food and agricultural industries need to be more frank about what they’re doing with our food. As Charlebois notes, they might want to invest in some public education, perhaps taking a leaf out of the Irish Food Board’s book and presenting the public with information both flattering and nonflattering about their efforts with our food.

Part one (an FOE report is published)

Part two (the problem with research)

ETA Aug. 22, 2014: Coincidentally, Michael Berger has written an Aug. 22, 2014 Nanowerk Spotlight article titled: How to identify nanomaterials in food.

ETA Sept. 1, 2014: Even more coincidentally, Michael Berger has written a 2nd Nanowerk Spotlight (dated Aug. 25, 2014) on the food and nano topic titled, ‘Nanotechnology in Agriculture’ based on the European Union’s Joint Research Centre’s ‘Workshop on Nanotechnology for the agricultural sector: from research to the field”, held on November 21-22 2013’.

Canada Grand Challenges May 2014 grants

Grand Challenges Canada (mentioned here many times including this Nov. 21, 2013 posting which featured their ‘Stars in Global Health’ programme grants announcement for Fall 2013) has announced a new round of awards. From a May 22, 2014 Grand Challenges Canada news release (can be found on EurekAlert),

Grand Challenges Canada, funded by the Government of Canada, today announces investments of $12 million in projects worldwide, aimed squarely at improving the health and saving the lives of mothers, newborns and children in developing countries.

The news release goes on to describe two different grants,

Four Canadian-based projects (from Guelph, Toronto, Waterloo and Winnipeg) with proven impact and sustainability will share $2.6 million in scale-up grants and loans from Grand Challenges Canada, matched by $2.6 million from private and public partners, bringing total “transition-to-scale” investments to $5.2 million.

In addition, Grand Challenges Canada “Stars in Global Health” [awarded] seed grants of $112,000 each ($6.8 million in total) …

[emphases mine]

I checked here to find Spring 2014 ‘Transition to scale’ grants and ‘Seed’ grants for the Canada Grand Challenges (GCC) programme.

I’m highlighting two of the funded projects. First, there’s ‘Lucky Iron Fish’ which won a ‘transition-scale-grant’ for the University of Guelph, from the news release on EurekAlert,

The little “Lucky Iron Fish,” now in growing use by cooks in Cambodia, has proven effective in reducing rampant iron deficiency among women – the cause of premature labour, hemorrhaging during childbirth and poor brain development among babies. Initial local reluctance to use a loose piece of iron in cooking pots was overcome by a clever design tapping into Cambodian folklore about a fish species that brings good fortune. In partnership with small businesses across Cambodia, plans for this year and next call for production and distribution of 60,000 lucky iron fish, made from recycled material at a cost of about $5 each, which provide health benefits for roughly three years.

(Lucky Iron Fish, Guelph, a transition-to-scale investment, grant #0355, video, images. More information: http://bit.ly/1mIZeWr)

Here’s more detail about the project from the GCC’s list of May 2014 successful GCC grants,

A lucky little fish to fight iron deficiency among women in Cambodia
Lucky Iron Fish, Guelph
Project number: 0355-05-30
Total new transition to scale investment: $860,000

In Cambodia, six in 10 women are anemic due to iron deficiency in their diets, causing premature labour, hemorrhaging during childbirth and the impaired brain development of their babies.

Usually obtained through red meat or other iron-rich foods, a small chunk of iron added to water in the cooking pot can release a life-saving iron supplement.  But attempts to persuaders to do so were unsuccessful.

On a 2008 study mission in Cambodia, University of Guelph researcher Chris Charles thought of creating a piece of iron shaped like a local river fish believed to bring good luck and fortune.

His simple idea succeeded beyond all expectations.  Women happily placed the Lucky Iron Fish in their cooking pots and, in the months that followed, anemia in the village fell dramatically.

A Lucky Iron Fish is small enough to be stirred easily but large enough to provide about 75 per cent of daily iron requirements.

“The results are stunning,” says Dr. Alastair Summerlee, President of the University of Guelph and Chair of the Board of Directors of Lucky Iron Fish. “Initial results show a huge decrease in anemia and the village women say they feel good, experience no dizziness and have fewer headaches. The iron fish is incredibly powerful.”

Small businesses across Cambodia will produce and distribute the fish with quality control measures in place.  About 7.5 cm (3 inches) long, and made from recycled material at a cost of about $5 each, the iron fish provides health benefits for roughly three years.

“Our goal is to produce 10,000 Lucky Iron Fish this year and another 150,000 next year,” says Gavin Armstrong, President and CEO of Lucky Iron Fish.

Taking the project to scale offers profound potential health benefits to many women in Cambodia with potential markets throughout the world.
Grand Challenges Canada’s $500,000 loan to Lucky Iron Fish is part of a total scale-up financing package of $860,000, and augments earlier commitments of equity investors, Innovation Guelph, and the University of Guelph.

The second one is a ‘Rising Star’ project at the University of Alberta. From a May 22, 2014 University of Alberta news release (also on EurekAlert but dated May 23, 2014),

A University of Alberta researcher’s star is rising thanks to her idea to detect deadly pathogens such as E. coli using a paper device only slightly larger than a postage stamp.

Frédérique Deiss, a post-doctoral fellow in the Faculty of Science, is working on ways to help detect food- and water-borne pathogens using a paper-based diagnostic tool that could be used anywhere, including developing countries. The idea earned the electrochemist $112,000 in research funding from Grand Challenges Canada after being selected as one of their Stars in Global Health.

For the next 18 months, Deiss will be working at the U of A and with farmers near Nairobi, Kenya, in collaboration with the International Livestock Research Institute, to develop and test a prototype that provides an affordable method for detecting pathogens such as salmonella or E. coli, which can be present in raw milk, on equipment, or in water or waste water.

“Some areas do not have the infrastructure to do this kind of monitoring all the time. These devices are simple and sensible enough to use that farmers could almost do the tests themselves, and test every day rather than once a week or even more sporadically,” said Deiss, who is working in the lab of Ratmir Derda.

Her idea for a diagnostic tool made of paper is just that at the moment—an idea. Funding from Grand Challenges Canada will allow her to develop an electrochemical diagnostic device made of paper and tape. Conductive ink applied to the paper would create an electrode that would allow researchers to detect the presence of targeted bacteria.

Slightly larger than a postage stamp and even cheaper to make at less than 10 cents, the device would be extremely portable, self-contained and sealed—meaning anyone performing the tests would not risk exposure to potentially harmful bacteria, Deiss said. It would also allow testing of non-purified samples—a time- and cost-saving step not possible in some parts of the world, including farms around Nairobi, she added.

Within six months, Deiss hopes to develop a working prototype capable of detecting non-pathogenic bacteria, and by one year a device able to safely detect deadly pathogens such as E. coli. She also plans to work with ILRI and farmers in Nairobi to test the device in the field, comparing results with conventional methods.

Here’s a video of Deiss describing her idea,

You can find more videos featuring researchers and their GCC projects on GCC’s YouTube channel.

I wish all the best of luck to all the researchers and I’m pretending to myself that the two projects featured here can be described as nanotechnology.

Kick up your heels to the periodic table of elements sung to the sounds of the can-can (Offenbach’s Infernal Galop)

First the fun (*ETA: June 17, 2016: Sadly, this video no longer seems to be freely available but there is an updated version in my June 17, 2016 posting about the provisional names for four new elements.),

You may to want to check out Jennifer Miller’s May 20, 2013 Fast Company article about this effort where she highlights one of the cheekier illustrations in this periodic table of elements song from AsapSCIENCE (Mitchell Moffit and Gregory Brown).

I found out more about AsapSCIENCE and the duo (former classmates at the University of Guelph in Ontario, Canada) in a Sept. 18, 2012 article by Chase Hoffberger for the Daily Dot,

Mitchell Moffit and Gregory Brown are the two former University of Guelph classmates behind asapSCIENCE, a young but massively informative and entertaining YouTube channel that produces three-minute lessons on all the scientific questions that you actually want answered: “The Scientific Power of Naps.” …

“We’re trying to keep a balance of the things that people want to know as well as cool tidbits that people would never have any idea about,” Moffit, 23, told the Daily Dot from his home in Ontario, where he holds down production and most video voiceovers while Brown spends the year teaching science in England.

“We’re interested in inspiring people who maybe don’t know a lot about science and think of it as this hard subject in school,” Moffit said.

The perfect example’s “The Science of Orgasms,” which more than 380,000 people have viewed in the past week and comes packed with far more knowledge and insight than the time your dad tried to put a condom on a cucumber.

At the time of the Daily Dot article (Sept. 2012), AsapSCIENCE had been making videos for three months and already had more than 40,000 subscribers on their YouTube channel. After checking this morning (May 21, 2013), I see the channel has over 784,000 subscribers. Bravo!

I have written about the periodic table of elements before. This Feb. 8, 2012 posting features Daniel Radcliffe (Harry Potter) singing Tom Lehrer’s classic Periodic Table of Elements song.