Tag Archives: University of Toronto

Nanotechnology in agriculture: an introduction and a 15th anniversary

It’s not often that I publish a posting meant for beginners since I tend to take an understanding of nanotechnology for granted. For anyone who has stumbled across this posting and needs an introduction to nanotechnology, M Cynthia Goh’s* (professor, Chemistry, University of Toronto) April 25, 2021 essay about nanotechnology and agriculture, on The Conversation website, provides a good entry point (Note 1: The excerpts are not in the order in which they appear in the essay Note 2: Links have been removed) ,

Nanotechnology is the science of objects that are a few nanometres — billionths of a metre — across. At this size, objects acquire unique properties. For example, the surface area of a swarm of nanoscale particles is enormous compared to the same mass collected into single large-scale clump.

Varying the size and other properties of nanoscale objects gives us an unprecedented ability to create precision surfaces with highly customized properties.

Agriculture is one of the oldest human inventions, but nanotech provides modern innovations that could dramatically improve the efficiency of our food supply and reduce the environmental impact of its production.

Agriculture comes with costs that farmers are only too familiar with: Crops require substantial amounts of water, land and fuel to produce. Fertilizers and pesticides are needed to achieve the necessary high crop yields, but their use comes with environmental side effects, even as many farmers explore how new technologies can reduce their impact.

Custom-made nanoscale systems can use precision chemistry to achieve high-efficiency delivery of fertilizers or pesticides. These active ingredients can be encapsulated in a fashion similar to what happens in targeted drug delivery. The encapsulation technique can also be used to increase the amount dissolved in water, reducing the need for large amounts.

Current applications

Starpharma, a pharmaceutical company, got into this game a few years ago, when it set up a division to apply its nanotechnological innovations to the agriculture sector. The company has since sold its agrochemical business.

Psigryph is another innovative nanotech company in agriculture. Its technology uses biodegradable nanostructures derived from Montmonercy sour cherries extract to deliver bioactive molecules across cell membranes in plants, animals and humans.

My lab has spent years working in nanoscience, and I am proud to see our fundamental understanding of manipulating polymer encapsulation at the nanoscale make its way to applications in agriculture. A former student, Darren Anderson, is the CEO of Vive Crop Protection [emphasis mine], named one of Canada’s top growing firms: they take chemical and biological pesticides and suspend them in “nanopackets” — which act as incredibly small polymer shuttles — to make them easily reach their target. The ingredients can be controlled and precisely directed when applied on crops.

*M Cynthia Goh was a co-founder of Vive Crop Protection but is not actively involved in the company. She receives funding from NSERC (Natural Sciences and Engineering Research Council) Canada and the Ontario Centre of Innovation.

Vive Crop Protection’s 15th anniversary

March 30, 2021 marked 15 years for Vive Crop Protection (formerly Vive Nano) according to the company’s March 30, 2021 news release. It’s been a number of years since I’ve written about the company and I’m glad to see they seem to be thriving. Chief Executive Officer (CEO), Darren Anderson (he was formerly the company’s Chief Technical Officer) was interviewed on camera by Kim Bolton for BNN Bloomberg; a link to the video is available from this April 29, 2021 Vive Crop news webpage.

(BTW, BNN Bloomberg is “(formerly Business News Network and Report on Business Television) is a Canadian English language specialty channel owned by Bell Media. It broadcasts programming related to business and financial news and analysis. Since April 30, 2018, the network has operated as a partner of the U.S. business channel Bloomberg Television, …” See more about BNN Bloomberg in its Wikipedia entry.)

For anyone interested in Vive Crop’s technology, see my December 31, 2013, posting.

Toronto’s ArtSci Salon and The Mutant Project March 15, 2021

The Mutant Project is both a book (The Mutant Project: Inside the Global Race to Genetically Modify Humans) and an event about gene editing with special reference to the CRISPR (clustered regularly interspaced short palindromic repeats) twins, Lulu and Nana. The event is being held by Toronto’s ArtSci Salon. Here’s more from their March 3, 2021 announcement (received via email),

The Mutant Project

A talk and discussion with Eben Kirksey

Discussants:

Dr. Elizabeth Koester, Postdoctoral fellow, Department of History, UofT [University of Toronto]

Vincent Auffrey, PhD student, IHPST [Institute for the History and Philosophy of Science and Technology], UofT

Fan Zhang, PhD student, IHPST, UofT

This event will be streamed on Zoom and on Youtube

Here is the link to register to Zoom on the 15th:

https://utoronto.zoom.us/meeting/registe/tZErcemoqzwrG9foNF5Ud86uJXdNeIzQSfDw

Event on FB: https://www.facebook.com/events/4033393163381012/

YouTube: https://www.youtube.com/watch?v=pEFfj3Ovsfk&feature=youtu.be

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for “illegal medical practice.”

As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society?

Join us to welcome Dr. Kirksey, who will discuss key topics from his book “The Mutant Project”.

The talk will be followed by a Q&A

EBEN KIRKSEY is an American anthropologist who finished his latest book as a Member of the Institute for Advanced Study in Princeton, New Jersey. He has been published in Wired, The Atlantic, The Guardian and The Sunday Times. He is sought out as an expert on science in society by the Associated Press, The Wall Street Journal, The New York Times, Democracy Now, Time and the BBC, among other media outlets. He speaks widely at the world’s leading academic institutions including Oxford, Yale, Columbia, UCLA, and the International Summit of Human Genome Editing, plus music festivals, art exhibits, and community events. Professor Kirksey holds a long-term position at Deakin University in Melbourne, Australia. For more information, please visit https://eben-kirksey.space/.

Elizabeth Koester currently holds a SSHRC [Social Science and Humanities Research Council of Canada] Postdoctoral Fellowship in the Department of History at the University of Toronto. After practising law for many years, she undertook graduate studies in the history of medicine at the Institute for the History and Philosophy of
Science and Technology at the University of Toronto and was awarded a PhD in 2018. A book based on her dissertation, In the Public Good: Eugenics and Law in Ontario, will be published by McGill-Queen’s University Press and is anticipated for Fall 2021.

Vincent Auffrey is pursuing his PhD at the Institute for the History of Philosophy of Science and Technology (IHPST) at the University of Toronto. His focus is set primarily on the social history of medicine and the history of eugenics in Canada. Secondary interests include the histories of scientific racism and of anatomy, and the interplay between knowledge and power.

Fan Zhang is a PhD student at the History of Philosophy of Science and Technology (IHPST) at the University of Toronto

Kirksey’s eponymous website,

FACTT (Festival of Art and Science) 2021: Improbable Times on Thursday, Jan.28.21 at 3:30 pm EST

Courtesy: Arte Institute

Plans for last year’s FACTT (Festival of Art and Science) 2020 had to be revised at the last minute due to COVID-19. This year, organizers were prepared so no in person sessions have to be cancelled or turned into virtual events. Here’s more from the Jan. 25, 2021 announcement I received (via email) from one of the festival partners, the ArtSci Salon at the University of Toronto,

Join us! Opening of FACTT 20-21 Improbable Times! 

Thursday, January 28, 2021 at 3:30 PM EST – 5:30 PM EST
Public  · Anyone on or off Facebook – link will be disseminated closer to the event.

The Arte Institute and the RHI Initiative, in partnership with Cultivamos Cultura, have the pleasure to present the FACTT 2021 – Festival Art & Science. The festival opens on January 28, at 8.30 PM (GMT), and will be exhibited online on RHI Stage.

This year we are reshaping FACTT! Come join us for the kick-off of this amazing project!

A project spearheaded and promoted by the Arte Institute we are in or production and conception partners with Cultivamos Cultura and Ectopia (Portugal), InArts Lab@Ionian University (Greece), ArtSci Salon@The Fields Institute and Sensorium@York University (Canada), School of Visual Arts (USA), UNAM, Arte+Ciência and Bioscenica (Mexico), and Central Academy of Fine Arts (China).

Together we will work and bring into being our ideas and actions for this during the year of 2021!

FACTT 20/21 – Improbable Times presents a series of exceptional artworks jointly curated by Cultivamos Cultura and our partners. The challenge of a translation from the physical space that artworks occupy typically, into an exhibition that lives as a hybrid experience, involves rethinking the materiality of the work itself. It also questions whether we can live and interact with each other remotely and in person producing creative effective collaborative outcomes to immerse ourselves in. Improbable Times brings together a collection of works that reflect the times we live in, the constraints we are faced with, the drive to rethink what tomorrow may bring us, navigate it and build a better future, beyond borders.

Watch online: RHI Stage platform – http://bit.ly/3bWCT64 OR on the RHI Think app OR at Arte Institute and RHI Think facebook pages. https://vimeo.com/arteinstitute and youtube @rhi_think

January 28, 2021 | 8:30 PM (GMT)Program:
– Introduction
– Performance Toronto: void * ambience : Latency, with Joel Ong, Michael Palumbo and Kavi
– Performance Mexico “El Tercero Cuerpo Sonoro” (Third Sonorous Body), by Arte+Ciência.
– Q&A

The performance series void * ambience experiments with sound and video
content that is developed through a focus on the topographies and networks through which these flow. Initiated during the time of COVID and social distancing, this project explores processes of information sharing, real-time performance and network communication protocols that contribute to the sustenance of our digital communities, shared experiences and telematic intimacies.

“El Tercero Cuerpo Sonoro” project is a digital drift that explores different relationships with the environment, nature, humans and non-humans from the formulation of an intersubjective body. Its main search is to generate resonances with and among the others.

In these complicated times in which it seems that our existence unfolds in front of the screen, confined to the space of the black mirror, it becomes urgent to challenge the limits and scopes of digital life. We need to rethink the way in which we inhabit the others as well as our own subjectivity.

IEither the RHI FACTT 2021 event page or the Arte Institute FACTT 2021 event page, offer a more detailed and, somewhat, more accessible description,

Program:
– Introduction
– Performance Toronto: Proximal Spaces
Artistic Directors: Joel Ong, Elaine Whittaker
Graphic Designer: Natalie Plociennik Bhavesh Kakwani
AR [augmented reality] development : Sachin Khargie, Ryan Martin
Bioartists: Roberta Buiani, Nathalie Dubois Calero, Sarah Choukah, Nicole Clouston, Jess Holtz, Mick Lorusso, Maro Pebo, Felipe Shibuya
– Performance Mexico Tercero Cuerpo Sonoro (Third Sonorous Body) by Arte+Ciência

FACTT team: Marta de Menezes, Suzanne Anker, Maria Antonia Gonzalez Valerio, Roberta Buiani, Jo Wei, Dalila Honorato, Joel Ong, Lena Lee and Minerva Ortiz.

For FACTT20/21 we propose to put together an exhibition where the virtual and the physical share space, a space that is hybrid from its conception, a space that desires to break the limits of access to culture, to collaboration, to the experience of art. A place where we can think deeply and creatively together about the adaptive moves we had and have to develop to the rapid and sudden changes our lives and environment are going through.

Enjoy!

Congratulations to Molly Shoichet (her hydrogels are used in regenerative medicine and more) for winning the $1 million Gerhard Herzberg Canada Gold Medal

I imagine that most anyone who’s been in contact with Ms. Shoichet is experiencing a thrill on hearing this morning’s (November 10, 2020) news about winning Canada’s highest honour for science and engineering research. (Confession: she, very kindly, once gave me a brief interview for a posting on this blog, more about that later).

Why Molly Shoichet won the Gerhard Herzberg Canada Gold Medal

Emily Chung’s Nov. 10, 2020 news item on the Canadian Broadcasting Corporation (CBC) website announces the exciting news (Note: Links have been removed),

A Toronto chemical engineering professor has won the $1 million Gerhard Herzberg Canada Gold Medal, the country’s top science prize, for her work designing gels that mimic human tissues.

The Natural Sciences and Engineering Research Council of Canada (NSERC) announced Tuesday [Nov. 10, 2020] that Molly Shoichet, professor of chemical engineering and applied chemistry and Canada Research Chair in Tissue Engineering at the University of Toronto is this year’s recipient of the award, which recognizes “sustained excellence” and “overall influence” of research conducted in Canada in the natural sciences or engineering.

Shoichet’s hydrogels are used for drug development and  delivery and regenerative medicine to heal injuries and treat diseases.

NSERC said Shoichet’s work has led to the development of several “game-changing” applications of such materials. They “delivered a crucial breakthrough” by allowing cells to be grown in three dimensions as they do in the body, rather than the two dimensions they typically do in a petri dish.

Hydrogels are polymer materials — materials such as plastics, made of repeating units — that become swollen with water.

“If you’ve ever eaten Jell-o, that’s a hydrogel,” Shoichet said. Slime and the absorbent material inside disposable diapers are also hydrogels.

Shoichet was born in Toronto, and studied science and engineering at the Massachusetts Institute of Technology and the University of Massachusetts Amherst. After graduating, she worked in the biotech industry alongside “brilliant biologists,” she said. She noticed that the biologists’ research was limited by what types of materials were available.

As an engineer, she realized she could help by custom designing materials for biologists. She could make materials specifically suit their needs, to answer their specific questions by designing hydrogels to mimic particular tissues.

Her collaborations with biologists have also generated three spinoff companies, including AmacaThera, which was recently approved to run human trials of a long-acting anesthetic delivered with an injectable hydrogel to deal with post-surgical pain.

Shoichet noted that drugs given to deal with that kind of pain lead to a quarter of opioid addictions, which have been a deadly problem in Canada and around the world.

“What we’re really excited about is not only meeting that critical need of providing people with greater pain relief for a sustained period of time, but also possibly putting a dent in the operation,” she said. 

Liz Do’s Nov. 10, 2020 University of Toronto news release provides more details (Note: Links have been removed),

The  Herzberg Gold Medal is awarded by the Natural Sciences and Engineering Research Council (NSERC) in recognition of research contributions characterized by both excellence and influence.

“I was completely overwhelmed when I was told the good news,” says Shoichet. “There are so many exceptional people who’ve won this award and I admire them. To think of my peers putting me in that same category is really incredible.”

A pioneer in regenerative medicine, tissue engineering and drug delivery, Shoichet and her team are internationally known for their discovery and innovative use of 3D hydrogels.

“One of the challenges facing drug screening is that many of the drugs discovered work well in the lab, but not in people, and a possible explanation for this discrepancy is that these drugs are discovered in environments that do not reflect that of the body,” explains Shoichet.

Shoichet’s team has invented a series of biomaterials that provide a soft, three-dimensional environment in which to grow cells. These hydrogels — water-swollen materials — better mimic human tissue than hard two-dimensional plastic dishes that are typically used. “Now we can do more predictive drug screening,” says Shoichet.

Her lab is using these biomaterials to discover drugs for breast and brain cancer and a rare lung disease. Shoichet’s lab has been equally innovative in regenerative medicine strategies to promote repair of the brain after stroke and overcome blindness.

“Everything that we do is motivated by answering a question in biology, using our engineering and chemistry tools to answer those questions,” says Shoichet.

“The hope is that our contributions will ultimately make a positive impact in the cancer community and in treating diseases for which we can only slow the progression rather than stop and reverse, such as with blindness.”

Shoichet is also an advocate for and advisor on the fields of science and engineering. She has advised both federal and provincial governments through her service on Canada’s Science, Technology and Innovation Council and the Ontario Research Innovation Council. From 2014 to 2018, she was the Senior Advisor to the President on Science & Engineering Engagement at the University of Toronto. She is the co-founder of Research2Reality [emphasis mine], which uses social media to promote innovative research across the country. She also served as Ontario’s first Chief Scientist [emphasis mine], with a mandate to advance science and innovation in the province.

Shoichet is the only person to be elected a fellow of all three of Canada’s National Academies and is a foreign member of the U.S. National Academy of Engineering, and fellow of the Royal Society (UK) — the oldest and most prestigious academic society.

Doug Ford (premier of Ontario) and Molly Shoichet

She did serve as Ontario’s first Chief Scientist—for about six months (Nov. 2017 – July 2018). Molly Shoichet was fired when a new provincial government was elected in the summer of 2018. Here’s more about the incident from a July 4, 2018 article by Ryan Maloney for huffingtonpost.ca (Note: Links have been removed),

New Ontario Premier Doug Ford has fired the province’s first chief scientist.

Dr. Molly Shoichet, a renowned biomedical engineer who teaches at the University of Toronto, was appointed in November [2017] to advise the government and ensure science and research were at the forefront of decision-making.

Shoichet told HuffPost Canada in an email that the she does not believe the decision was about her, and “I don’t even know whether it was about this role.” She said she is disappointed but honoured to have served Ontarians, even for a short time.

Ford’s spokesman, Simon Jefferies told The Canadian Press Wednesday that the government is starting the process of “finding a suitable and qualified replacement.” [emphasis mine]

The move comes just days after Ford’s Progressive Conservatives officially took power in Canada’s largest province with a majority government.

Almost a year later, there was no replacement in sight according to a June 24, 2019 opinion piece by Kimberly Girling (then the Research and Policy Director of the Evidence for Democracy not-for-profit) for the star.com,

Premier Doug Ford, I’m concerned for your government.

I know you feel it too. Last week, one year into your mandate and faced with sharply declining polls after your first provincial budget, you conducted a major cabinet shuffle. This shuffle is clearly an attempt to “put the right people in the right place at the right time” and improve the outcomes of your cabinet. But I’m still concerned.

Since your election, your caucus has made many bold decisions. Unfortunately, it seems many are Ontarians unhappy with most of these decisions, and I’m not sure the current shuffle is enough to fix this.

[] I think you’re missing someone.

What about a Chief Scientist?

It isn’t a radical idea. Actually, you used to have one. Ontario’s first Chief Scientist, Dr. Molly Shoichet, was appointed to advise the government on science policy and champion science and innovation for Ontario. However, when your government was elected, you fired Dr. Shoichet within the first week.

It’s been a year, and so far we haven’t seen any attempts to fill this vacant position. [emphasis mine]

I wonder if Doug Ford and his crew regret the decision to fire Shoichet especially now that the province is suffering from a new peak in rising COVID-19 case numbers. These days government could do with a little bit of good news.

The only way we might ever know is if Doug Ford writes a memoir (in about 20 or 30 years from now).

Molly Shoichet, Research2Reality, and FrogHeart

A May 11, 2015 posting announced the launch of Research2Reality and it’s in this posting that I have a few comments from Molly Shoichet about co-founding a national science communication project. Given how busy she was at the time, I was amazed she took a few minutes to speak to me and took more time to make it possible for me to interview Raymond Laflamme (then director of the Institute for Quantum Computing at the University of Waterloo [Ontario]) and a prominent physicist.

Here are the comments Molly Shoichet offered (from the May 11, 2015 posting),

“I’m very excited about this and really hope that other people will be too,” says Shoichet. The audience for the Research2Reality endeavour is for people who like to know more and have questions when they see news items about science discoveries that can’t be answered by investigating mainstream media programmes or trying to read complex research papers.

This is a big undertaking. ” Mike [Mike MacMillan, co-founder] and I thought about this for about two years.” Building on the support they received from the University of Toronto, “We reached out to the vice-presidents of research at the top fifteen universities in the country.” In the end, six universities accepted the invitation to invest in this project,

Five years later, it’s still going.

Finally: Congratulations Molly Shoichet!

7th annual Vancouver Nanomedicine Day, Sept. 17, 2020

Like so many events these days (COVID-19 days), this event put on by Canada’s NanoMedicines Innovation Network (NMIN) will be held virtually. Here’s more from the ‘Virtual’ Vancouver Nanomedicine Day 2020 event page on the NMIN website,

This world-class symposium, the sixth event of its kind, will bring together a record number (1000+) of renowned Canadian and international experts from across the nanomedicines field to:

  • highlight the discoveries and innovations in nanomedicines that are contributing to global progress in acute, chronic and orphan disease treatment and management;
  • present up-to-date diagnostic and therapeutic  nanomedicine approaches to addressing the challenges of COVID-19; and
  • facilitate discussion among nanomedicine researchers and innovators and UBC and NMIN clinician-scientists, basic researchers, trainees, and research partners.

Since 2014, Vancouver Nanomedicine Day has advanced nanomedicine research, knowledge mobilization and commercialization in Canada by sharing high-impact findings and facilitating interaction—among researchers, postdoctoral fellows, graduate students, and life science and startup biotechnology companies—to catalyze research collaboration.

Here are a few highlights from the ‘Virtual’ Vancouver Nanomedicine Day 2020 event page,

  • An introduction to nanomedicines by Dr. Emmanuel Ho (University of Waterloo)
  • A keynote address by an iconic nanomedicine innovator: Dr. Robert Langer (MIT, Department of Chemical Engineering)
  • Invited talks by internationally renowned experts, including Dr. Vito Foderà (The University of Copenhagen, Denmark); Dr. Lucia Gemma Delogu (University of Padova, Italy); and Dr. Christine Allen (University of Toronto)
  • A virtual poster competition, with cash prizes for the top posters
  • A debate on whether “nanomedicines are still the next big thing” between Marcel Bally (proponent) and Kishor Wasan (opponent)

You can get the Program in PDF.

Registration is free. But you must Register.

Here’s the event poster,

[downloaded from https://www.nanomedicines.ca/nmd-2020/]

I have a few observations, First, Robert Langer is a big deal. Here are a few highlights from his Wikipedia entry (Note: Links have been removed),

Robert Samuel Langer, Jr. FREng[2] (born August 29, 1948) is an American chemical engineer, scientist, entrepreneur, inventor and one of the twelve Institute Professors at the Massachusetts Institute of Technology.[3]

Langer holds over 1,350 granted or pending patents.[3][29] He is one of the world’s most highly cited researchers, having authored nearly 1,500 scientific papers, and has participated in the founding of multiple technology companies.[30][31]

Langer is the youngest person in history (at 43) to be elected to all three American science academies: the National Academy of Sciences, the National Academy of Engineering and the Institute of Medicine. He was also elected as a charter member of National Academy of Inventors.[32] He was elected as an International Fellow[2] of the Royal Academy of Engineering[2] in 2010.

It’s all about commercializing the research—or is it?

(This second observation is a little more complicated and requires a little context.) The NMIN is one of Canada’s Networks of Centres of Excellence (who thought that name up? …sigh), from the NMIN About page,

NMIN is funded by the Government of Canada through the Networks of Centres of Excellence (NCE) Program.

The NCEs seem to be firmly fixed on finding pathways to commercialization (from the NCE About page) Note: All is not as it seems,

Canada’s global economic competitiveness [emphasis mine] depends on making new discoveries and transforming them into products, services [emphasis mine] and processes that improve the lives of Canadians. To meet this challenge, the Networks of Centres of Excellence (NCE) offers a suite of programs that mobilize Canada’s best research, development and entrepreneurial [emphasis mine] expertise and focus it on specific issues and strategic areas.

NCE programs meet Canada’s needs to focus a critical mass of research resources on social and economic challenges, commercialize [emphasis mine] and apply more of its homegrown research breakthroughs, increase private-sector R&D, [emphasis mine] and train highly qualified people. As economic [emphasis mine] and social needs change, programs have evolved to address new challenges.

Interestingly, the NCE is being phased out,

As per the December 2018 NCE Program news, funding for the Networks of Centres of Excellence (NCE) Program will be gradually transferred to the New Frontiers in Research Fund (NFRF).

The new agency, NFRF, appears to have a completely different mandate, from the NFRF page on the Canada Research Coordinating Committee webspace,

The Canada Research Coordinating Committee designed the New Frontiers in Research Fund (NFRF) following a comprehensive national consultation, which involved Canadian researchers, research administrators, stakeholders and the public. NFRF is administered by the Tri-agency Institutional Programs Secretariat, which is housed within the Social Sciences and Humanities Research Council (SSHRC), on behalf of Canada’s three research granting agencies: the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council and SSHRC.

The fund will invest $275 million over the next 5 years beginning in fiscal 2018-19, and $65 million ongoing, to fund international, interdisciplinary, fast-breaking and high-risk research.

NFRF is composed of three streams to support groundbreaking research.

  • Exploration generates opportunities for Canada to build strength in high-risk, high-reward and interdisciplinary research;
  • Transformation provides large-scale support for Canada to build strength and leadership in interdisciplinary and transformative research; and
  • International enhances opportunities for Canadian researchers to participate in research with international partners.

As you can see there’s no reference to commercialization or economic challenges.

Personally

Here at last is the second observation, I find it hard to believe that the government of Canada has given up on the idea of commercializing research and increasing the country’s economic competitiveness through research. Certainly, Langer’s virtual appearance at Vancouver Nanomedicine Day 2020, suggests that at least some corners of the Canadian research establishment are remaining staunchly entrepreneurial.

After all, the only Canadian government ministry with science in its name is this one: Innovation, Science and Economic Development Canada (ISED), as of Sept. 11, 2020.. (The other ‘science’ ministries are Natural Resources Canada, Environment and Climate Change Canada, Fisheries and Oceans Canada, Health Canada, and Agriculture and Agri-Food Canada.) ISED is not exactly subtle. Intriguingly the latest review on the state of science and technology in Canada was released on April 10, 2018 (from the April 10, 2018 Council of Canadian Academies CCA] news release),

Canada remains strong in research output and impact, capacity for R&D and innovation at risk: New expert panel report

While Canada is a highly innovative country, with a robust research base and thriving communities of technology start-ups, significant barriers—such as a lack of managerial skills, the experience needed to scale-up companies, and foreign acquisition of high-tech firms—often prevent the translation of innovation into wealth creation.[emphasis mine] The result is a deficit of technology companies growing to scale in Canada, and a loss of associated economic and social benefits.This risks establishing a vicious cycle, where successful companies seek growth opportunities elsewhere due to a lack of critical skills and experience in Canada guiding companies through periods of rapid expansion.

According to the CCA’s [2018 report] Summary webpage, it was Innovation, Science and Economic Development Canada which requested the report. (I wrote up a two-part commentary under one of my favourite titles: “The Hedy Lamarr of international research: Canada’s Third assessment of The State of Science and Technology and Industrial Research and Development in Canada.” Part 1 and Part 2)

I will be fascinated to watch the NFRF and science commercialization situations as they develop.

In the meantime, you can sign up for free to attend the ‘Virtual’ Vancouver Nanomedicine Day 2020.

Graphene fatigue

Graphene fatigue operates under the same principle as metal fatigue. Subject graphene to stress over and over and at some point it (just like metal) will fail. Scientists at the University of Toronto (Ontatrio, Canada) and Rice University (Texas, US) have determined just how much stress graphene can withstand before breaking according to a January 28, 2020 University of Toronto news release by Tyler Irving (also on EurekAlert but published on January 29, 2020),

Graphene is a paradox. It is the thinnest material known to science, yet also one of the strongest. Now, research from University of Toronto Engineering shows that graphene is also highly resistant to fatigue — able to withstand more than a billion cycles of high stress before it breaks.

Graphene resembles a sheet of interlocking hexagonal rings, similar to the pattern you might see in bathroom flooring tiles. At each corner is a single carbon atom bonded to its three nearest neighbours. While the sheet could extend laterally over any area, it is only one atom thick.

The intrinsic strength of graphene has been measured at more than 100 gigapascals, among the highest values recorded for any material. But materials don’t always fail because the load exceeds their maximum strength. Stresses that are small but repetitive can weaken materials by causing microscopic dislocations and fractures that slowly accumulate over time, a process known as fatigue.

“To understand fatigue, imagine bending a metal spoon,” says Professor Tobin Filleter, one of the senior authors of the study, which was recently published in Nature Materials. “The first time you bend it, it just deforms. But if you keep working it back and forth, eventually it’s going to break in two.”

The research team — consisting of Filleter, fellow University of Toronto Engineering professors Chandra Veer Singh and Yu Sun, their students, and collaborators at Rice University — wanted to know how graphene would stand up to repeated stresses. Their approach included both physical experiments and computer simulations.

“In our atomistic simulations, we found that cyclic loading can lead to irreversible bond reconfigurations in the graphene lattice, causing catastrophic failure on subsequent loading,” says Singh, who along with postdoctoral fellow Sankha Mukherjee led the modelling portion of the study. “This is unusual behaviour in that while the bonds change, there are no obvious cracks or dislocations, which would usually form in metals, until the moment of failure.”

PhD candidate Teng Cui, who is co-supervised by Filleter and Sun, used the Toronto Nanofabrication Centre to build a physical device for the experiments. The design consisted of a silicon chip etched with half a million tiny holes only a few micrometres in diameter. The graphene sheet was stretched over these holes, like the head of a tiny drum.

Using an atomic force microscope, Cui then lowered a diamond-tipped probe into the hole to push on the graphene sheet, applying anywhere from 20 to 85 per cent of the force that he knew would break the material.

“We ran the cycles at a rate of 100,000 times per second,” says Cui. “Even at 70 per cent of the maximum stress, the graphene didn’t break for more than three hours, which works out to over a billion cycles. At lower stress levels, some of our trials ran for more than 17 hours.”

As with the simulations, the graphene didn’t accumulate cracks or other tell-tale signs of stress — it either broke or it didn’t.

“Unlike metals, there is no progressive damage during fatigue loading of graphene,” says Sun. “Its failure is global and catastrophic, confirming simulation results.”

The team also tested a related material, graphene oxide, which has small groups of atoms such as oxygen and hydrogen bonded to both the top and bottom of the sheet. Its fatigue behaviour was more like traditional materials, in that the failure was more progressive and localized. This suggests that the simple, regular structure of graphene is a major contributor to its unique properties.

“There are no other materials that have been studied under fatigue conditions that behave the way graphene does,” says Filleter. “We’re still working on some new theories to try and understand this.”

In terms of commercial applications, Filleter says that graphene-containing composites — mixtures of conventional plastic and graphene — are already being produced and used in sports equipment such as tennis rackets and skis.

In the future, such materials may begin to be used in cars or in aircraft, where the emphasis on light and strong materials is driven by the need to reduce weight, improve fuel efficiency and enhance environmental performance.

“There have been some studies to suggest that graphene-containing composites offer improved resistance to fatigue, but until now, nobody had measured the fatigue behaviour of the underlying material,” he says. “Our goal in doing this was to get at that fundamental understanding so that in the future, we’ll be able to design composites that work even better.”

Here’s a link to and a citation for the paper,

Fatigue of graphene by Teng Cui, Sankha Mukherjee, Parambath M. Sudeep, Guillaume Colas, Farzin Najafi, Jason Tam, Pulickel M. Ajayan, Chandra Veer Singh, Yu Sun & Tobin Filleter. Nature Materials (2020) DOI: DOIhttps://doi.org/10.1038/s41563-019-0586-y Published: 20 January 2020

This paper is behind a paywall.

Colloidal quantum dots as ultra-sensitive hyper-spectral photodetectors

An October 16, 2019 news item on Nanowerk announces some of the latest work with colloidal quantum dots,

Researchers of the Optoelectronics and Measurement Techniques Unit (OPEM) at the University of Oulu [Finland] have invented a new method of producing ultra-sensitive hyper-spectral photodetectors. At the heart of the discovery are colloidal quantum dots, developed together with the researchers at the University of Toronto, Canada.

Quantum dots are tiny particles of 15-150 atoms of semiconducting material that have extraordinary optical and electrical properties due to quantum mechanics phenomena.

By controlling the size of the dots, the researchers are able to finetune how they react to different light colors (light wavelengths), especially those invisible for the human eye, namely the infrared spectrum.

The figure briefly introduces the concept of the study conducted by the researchers of the University of Oulu and the University of Toronto. The solution consisting of colloidal quantum dots is inkjet-printed, creating active photosensitive layer of the photodetector. Courtesy: Oulu University

An October 16, 2019 Oulu University press release, which originated the news item, provides more detail,

-Naturally, it is very rewarding that our hard work has been recognized by the international scientific community but at the same time, this report helps us to realize that there is a long journey ahead in incoming years. This publication is especially satisfying because it is the result of collaboration with world-class experts at the University of Toronto, Canada. This international collaboration where we combined the expertise of Toronto’s researchers in synthesizing quantum dots and our expertise in printed intelligence resulted in truly unique devices with astonishing performance, says docent Rafal Sliz, a leading researcher in this project.
 
Mastered in the OPEM unit, inkjet printing technology makes possible the creation of optoelectronic devices by designing functional inks that are printed on various surfaces, for instance, flexible substrates, clothing or human skin. Inkjet printing combined with colloidal quantum dots allowed the creation of photodetectors of impresive detectivity characteristics. The developed technology is a milestone in the creation of a new type of sub-micron-thick, flexible, and inexpensive IR sensing devices, the next generation of solar cells and other novel photonic systems.

-Oulus’ engineers and scientists’ strong expertise in optoelectronics resulted in many successful Oulu-based companies like Oura, Specim, Focalspec, Spectral Engines, and many more. New optoelectronic technologies, materials, and methods developed by our researchers will help Oulu and Finland to stay at the cutting edge of innovation, says professor Tapio Fabritius, a leader of the OPEM.

Here’s a link to and a citation for the paper,

Stable Colloidal Quantum Dot Inks Enable Inkjet-Printed High-Sensitivity Infrared Photodetectors by Rafal Sliz, Marc Lejay, James Z. Fan, Min-Jae Choi, Sachin Kinge, Sjoerd Hoogland, Tapio Fabritius, F. Pelayo García de Arquer, Edward H. Sargent. ACS Nano 2019 DOI: https://doi.org/10.1021/acsnano.9b06125 Publication Date:September 23, 2019 Copyright © 2019 American Chemical Society

This paper is behind a paywall.

Science and technology, the 2019 Canadian federal government, and the Phoenix Pay System

This posting will focus on science, technology, the tragic consequence of bureaucratic and political bungling (the technology disaster that is is the Phoenix payroll system), and the puzzling lack of concern about some of the biggest upcoming technological and scientific changes in government and society in decades or more.

Setting the scene

After getting enough Liberal party members elected to the Canadian Parliament’s House of Commons to form a minority government in October 2019, Prime Minister Justin Trudeau announced a new cabinet and some changes to the ‘science’ portfolios in November 2019. You can read more about the overall cabinet announcement in this November 20, 2019 news item by Peter Zimonjic on the Canadian Broadcasting Corporation (CBC) website, my focus will be the science and technology. (Note: For those who don’t know, there is already much discussion about how long this Liberal minority government will last. All i takes is a ‘loss of confidence’ motion and a majority of the official opposition and other parties to vote ‘no confidence’ and Canada will back into the throes of an election. Mitigating against a speedy new federal election,, the Conservative party [official opposition] needs to choose a new leader and the other parties may not have the financial resources for another federal election so soon after the last one.)

Getting back to now and the most recent Cabinet announcements, it seems this time around, there’s significantly less interest in science. Concerns about this were noted in a November 22, 2019 article by Ivan Semeniuk for the Globe and Mail,

Canadian researchers are raising concerns that the loss of a dedicated science minister signals a reduced voice for their agenda around the federal cabinet table.

“People are wondering if the government thinks its science agenda is done,” said Marie Franquin, a doctoral student in neuroscience and co-president of Science and Policy Exchange, a student-led research-advocacy group. “There’s still a lot of work to do.”

While not a powerful player within cabinet, Ms. Duncan [Kirsty Duncan] proved to be an ardent booster of Canada’s research community and engaged with its issues, including the muzzling of federal scientists by the former Harper government and the need to improve gender equity in the research ecosystem.

Among Ms. Duncan’s accomplishments was the appointment of a federal chief science adviser [sic] and the commissioning of a landmark review of Ottawa’s support for fundamental research, chaired by former University of Toronto president David Naylor

… He [Andre Albinati, managing principal with Earnscliffe Strategy Group] added the role of science in government is now further bolstered by chief science adviser [sic] Mona Nemer and a growing network of departmental science advisers [sic]. .

Mehrdad Hariri, president of the Canadian Science Policy Centre …, cautioned that the chief science adviser’s [sic] role was best described as “science for policy,” meaning the use of science advice in decision-making. He added that the government still needed a separate role like that filled by Ms. Duncan … to champion “policy for science,” meaning decisions that optimize Canada’s research enterprise.

There’s one other commentary (by CresoSá) but I’m saving it for later.

The science minister disappears

There is no longer a separate position for Science. Kirsty Duncan was moved from her ‘junior’ position as Minister of Science (and Sport) to Deputy Leader of the government. Duncan’s science portfolio has been moved over to Navdeep Bains whose portfolio evolved from Minister of Innovation, Science and Economic Development (yes, there were two ‘ministers of science’) to Minister of Innovation, Science and Industry. (It doesn’t make a lot of sense to me. Sadly, nobody from the Prime Minister’s team called to ask for my input on the matter.)

Science (and technology) have to be found elsewhere

There’s the Natural Resources (i.e., energy, minerals and metals, forests, earth sciences, mapping, etc.) portfolio which was led by Catherine McKenna who’s been moved over to Infrastructure and Communities. There have been mumblings that she was considered ‘too combative’ in her efforts. Her replacement in Natural Resources is Seamus O’Regan. No word yet on whether or not, he might also be ‘too combative’. Of course, it’s much easier if you’re female to gain that label. (You can read about the spray-painted slurs found on the windows of McKenna’s campaign offices after she was successfully re-elected. See: Mike Blanchfield’s October 24, 2019 article for Huffington Post and Brigitte Pellerin’s October 31, 2019 article for the Ottawa Citizen.)

There are other portfolios which can also be said to include science such as Environment and Climate Change which welcomes a new minister, Jonathan Wilkinson moving over from his previous science portfolio, Fisheries, Oceans, and Canadian Coast Guard where Bernadette Jordan has moved into place. Patti Hajdu takes over at Heath Canada (which despite all of the talk about science muzzles being lifted still has its muzzle in place). While it’s not typically considered a ‘science’ portfolio in Canada, the military establishment regardless of country has long been considered a source of science innovation; Harjit Sajjan has retained his Minister of National Defence portfolio.

Plus there are at least half a dozen other portfolios that can be described as having significant science and/or technology elements folded into their portfolios, e.g., Transport Canada, Agriculture and Agri-Food, Safety and Emergency Preparedness, etc.

As I tend to focus on emerging science and technology, most of these portfolios are not ones I follow even on an irregular basis meaning I have nothing more to add about them in this posting. Mixing science and technology together in this posting is a reflection of how tightly the two are linked together. For example, university research into artificial intelligence is taking place on theoretical levels (science) and as applied in business and government (technology). Apologies to the mathematicians but this explanation is already complicated and I don’t think I can do justice to their importance.

Moving onto technology with a strong science link, this next portfolio received even less attention than the ‘science’ portfolios and I believe that’s undeserved.

The Minister of Digital Government and a bureaucratic débacle

These days people tend to take the digital nature of daily life for granted and that may be why this portfolio has escaped much notice. When the ministerial posting was first introduced, it was an addition to Scott Brison’s responsibilities as head of the Treasury Board. It continued to be linked to the Treasury Board when Joyce Murray* inherited Brison’s position, after his departure from politics. As of the latest announcement in November 2019, Digital Government and the Treasury Board are no longer tended to by the same cabinet member.

The new head of the Treasury Board is Jean-Yves Duclos while Joyce Murray has held on to the Minister of Digital Government designation. I’m not sure if the separation from the Treasury Board is indicative of the esteem the Prime Minister has for digital government or if this has been done to appease someone or some group, which means the digital government portfolio could well disappear in the future just as the ‘junior’ science portfolio did.

Regardless, here’s some evidence as to why I think ‘digital government’ is unfairly overlooked, from the minister’s December 13, 2019 Mandate Letter from the Prime Minister (Note: All of the emphases are mine],

I will expect you to work with your colleagues and through established legislative, regulatory and Cabinet processes to deliver on your top priorities. In particular, you will:

  • Lead work across government to transition to a more digital government in order to improve citizen service.
  • Oversee the Chief Information Officer and the Canadian Digital Service as they work with departments to develop solutions that will benefit Canadians and enhance the capacity to use modern tools and methodologies across Government.
  • Lead work to analyze and improve the delivery of information technology (IT) within government. This work will include identifying all core and at-risk IT systems and platforms. You will lead the renewal of SSC [Shared Services Canada which provides ‘modern, secure and reliable IT services so federal organizations can deliver digital programs and services to meet Canadians’ needs’] so that it is properly resourced and aligned to deliver common IT infrastructure that is reliable and secure.
  • Lead work to create a centre of expertise that brings together the necessary skills to effectively implement major transformation projects across government, including technical, procurement and legal expertise.
  • Support the Minister of Innovation, Science and Industry in continuing work on the ethical use of data and digital tools like artificial intelligence for better government.
  • With the support of the President of the Treasury Board and the Minister of Families, Children and Social Development, accelerate progress on a new Government of Canada service strategy that aims to create a single online window for all government services with new performance standards.
  • Support the Minister of Families, Children and Social Development in expanding and improving the services provided by Service Canada.
  • Support the Minister of National Revenue on additional steps required to meaningfully improve the satisfaction of Canadians with the quality, timeliness and accuracy of services they receive from the Canada Revenue Agency.
  • Support the Minister of Public Services and Procurement in eliminating the backlog of outstanding pay issues for public servants as a result of the Phoenix Pay System.
  • Lead work on the Next Generation Human Resources and Pay System to replace the Phoenix Pay System and support the President of the Treasury Board as he actively engages Canada’s major public sector unions.
  • Support the Minister of Families, Children and Social Development and the Minister of National Revenue to implement a voluntary, real-time e-payroll system with an initial focus on small businesses.
  • Fully implement lessons learned from previous information technology project challenges and failures [e,g, the Phoenix Payroll System], particularly around sunk costs and major multi-year contracts. Act transparently by sharing identified successes and difficulties within government, with the aim of constantly improving the delivery of projects large and small.
  • Encourage the use and development of open source products and open data, allowing for experimentation within existing policy directives and building an inventory of validated and secure applications that can be used by government to share knowledge and expertise to support innovation.

To be clear, the Minister of Digital Government is responsible (more or less) for helping to clean up a débacle, i.e., the implementation of the federal government’s Phoenix Payroll System and drive even more digitization and modernization of government data and processes.

They’ve been trying to fix the Phoenix problems since the day it was implemented in early 2016.That’s right, it will be four years in Spring 2020 when the Liberal government chose to implement a digital payroll system that had been largely untested and despite its supplier’s concerns.

The Phoenix Pay System and a great sadness

The Public Service Alliance of Canada (the largest union for federal employees; PSAC) has a separate space for Phoneix on its website, which features this video,

That video was posted on September 24, 2018 (on YouTube) and, to my knowledge, the situation has not changed appreciably. A November 8, 2019 article by Tom Spears for the Ottawa Citizen details a very personal story about what can only be described as a failure on just about every level you can imagine,

Linda Deschâtelets’s death by suicide might have been prevented if the flawed Phoenix pay system hadn’t led her to emotional and financial ruin, a Quebec coroner has found.

Deschâtelets died in December of 2017, at age 52. At the time she was struggling with chronic pain and massive mortgage payments.

The fear of losing her home weighed heavily on her. In her final text message to one of her sons she said she had run out of energy and wanted to die before she lost her house in Val des Monts.

But Deschâtelets might have lived, says a report from coroner Pascale Boulay, if her employer, the Canada Revenue Agency, had shown a little empathy.

“During the final months before her death, she experienced serious financial troubles linked to the federal government’s pay system, Phoenix, which cut off her pay in a significant way, making her fear she would lose her house,” said Boulay’s report.

“A thorough analysis of this case strongly suggests that this death could have been avoided if a search for a solution to the current financial, psychological and medical situation had been made.”

Boulay found “there is no indication that management sought to meet Ms. Deschâtelets to offer her options. In addition, the lack of prompt follow-up in the processing of requests for information indicates a distressing lack of empathy for an employee who is experiencing real financial insecurity.”

Pay records “indeed show that she was living through serious financial problems and that she received irregular payments since the beginning of October 2017,” the coroner wrote.

As well, “her numerous online applications using the form for a compensation problem, in which she expresses her fear of not being able to make her mortgage payments and says that she wants a detailed statement of account, remain unanswered.”

On top of that, she had chronic back pain and sciatica and had been missing work. She was scheduled to get an ergonomically designed work area, but this change was never made even though she waited for months.

Money troubles kept getting worse.

She ran out of paid sick leave, and her department sent her an email to explain that she had automatically been docked pay for taking sick days. “In this same email, she was also advised that in the event that she missed additional days, other amounts would be deducted. No further follow-up with her was done,” the coroner wrote.

That email came eight days before her death.

Deschâtelets was also taking cocaine but this did not alter the fact that she genuinely risked losing her home over her financial problems, the coroner wrote.

“Given the circumstances, it is highly likely that Ms. Deschâtelets felt trapped” and ended her life “because of her belief that she would lose the house anyway. It was only a matter of time.”

The situation is “even more sad” because CRA had advisers on site who dealt with Phoenix issues, and could meet with employees, Boulay wrote.

“The federal government does a lot of promotion of workplace wellness. Surprisingly, these wellness measures are silent on the subject of financial insecurity at work,” Boulay wrote.

I feel sad for the family and indignant that there doesn’t seem to have been enough done to mitigate the hardships due to an astoundingly ill-advised decision to implement an untested payroll system for the federal government’s 280,000 or more civil servants.

Canada’s Senate reports back on Phoenix

I’m highlighting the Senate report here although there are also two reports from the Auditor General should you care to chase them down. From an August 1, 2018 article by Brian Jackson for IT World Canada,

In February 2016, in anticipation of the start of the Phoenix system rolling out, the government laid off 2,700 payroll clerks serving 120,000 employees. [I’m guessing the discrepancy in numbers of employees may be due to how the clerks were laid off, i.e., if they were load off in groups scheduled to be made redundant at different intervals.]

As soon as Phoenix was launched, problems began. By May 2018 there were 60,000 pay requests backlogged. Now the government has dedicated resources to explaining to affected employees the best way to avoid pay-related problems, and to file grievances related to the system.

“The causes of the failure are multiple, including, failing to manage the pay system in an integrated fashion with human resources processes, not conducting a pilot project, removing essential processing functions to stay on budget, laying off experienced compensation advisors, and implementing a pay system that wasn’t ready,” the Senate report states. “We are dismayed that this project proceeded with minimal independent oversight, including from central agencies, and that no one has accepted responsibility for the failure of Phoenix or has been held to account. We believe that there is an underlying cultural problem that needs to be addressed. The government needs to move away from a culture that plays down bad news and avoids responsibility, [emphasis mine] to one that encourages employee engagement, feedback and collaboration.”

There is at least one estimate that the Phoenix failure will cost $2.2 billion but I’m reasonably certain that figure does not include the costs of suicide, substance abuse, counseling, marriage breakdown, etc. (Of course, how do you really estimate the cost of a suicide or a marriage breakdown or the impact that financial woes have on children?)

Also concerning the Senate report, there is a July 31, 2018 news item on CBC (Canadian Broadcasting Corporation) news online,

“We are not confident that this problem has been solved, that the lessons have all been learned,” said Sen. André Pratte, deputy chair of the committee. [emphases mine]

I haven’t seen much coverage about the Phoenix Pay System recently in the mainstream media but according to a December 4, 2019 PSAC update,

The Parliamentary Budget Officer has said the Phoenix situation could continue until 2023, yet government funding commitments so far have fallen significantly short of what is needed to end the Phoenix nightmare. 

PSAC will continue pressing for enough funding and urgent action:

  • eliminate the over 200,000 cases in the pay issues backlog
  • compensate workers for their many hardships
  • stabilize Phoenix
  • properly develop, test and launch a new pay system

2023 would mean the débacle had a seven year lifespan, assuming everything has been made better by then.

Finally, there seems to be one other minister tasked with the Phoenix Pay System ‘fix’ (December 13, 2019 mandate letter) and that is the Minister of Public Services and Procurement, Anita Anand. She is apparently a rookie MP (member of Parliament), which would make her a ‘cabinet rookie’ as well. Interesting choice.

More digital for federal workers and the Canadian public

Despite all that has gone before, the government is continuing in its drive to digitize itself as can be seen in the Minister of Digital Government’s mandate letter (excerpted above in ‘The Minister of Digital Government and some …’ subsection) and on the government’s Digital Government webspace,

Our digital shift to becoming more agile, open, and user-focused. We’re working on tomorrow’s Canada today.

I don’t find that particularly reassuring in light of the Phoenix Payroll System situation. However, on the plus side, Canada has a Digital Charter with 10 principles which include universal access, safety and security, control and consent, etc. Oddly, it looks like it’s the Minister of Justice and Attorney General of Canada, the Minister of Canadian Heritage and the Minister of Innovation, Science and Industry who are tasked with enhancing and advancing the charter. Shouldn’t this group also include the Minister of Digital Government?

The Minister of Digital Government, Joyce Murray, does not oversee a ministry and I think that makes this a ‘junior’ position in much the same way the Minister of Science was a junior position. It suggests a mindset where some of the biggest changes to come for both employees and the Canadian public are being overseen by someone without the resources to do the work effectively or the bureaucratic weight and importance to ensure the changes are done properly.

It’s all very well to have a section on the Responsible use of artificial intelligence (AI) on your Digital Government webspace but there is no mention of ways and means to fix problems. For example, what happens to people who somehow run into an issue that the AI system can’t fix or even respond to because the algorithm wasn’t designed that way. Ever gotten caught in an automated telephone system? Or perhaps more saliently, what about the people who died in two different airplane accidents due to the pilots’ poor training and an AI system? (For a more informed view of the Boeing 737 Max, AI, and two fatal plane crashes see: a June 2, 2019 article by Rachel Kraus for Mashable.)

The only other minister whose mandate letter includes AI is the Minister of Innovation, Science and Industry, Navdeep Bains (from his December 13, 2019 mandate letter),

  • With the support of the Minister of Digital Government, continue work on the ethical use of data and digital tools like artificial intelligence for better government.

So, the Minister of Digital Government, Joyce Murray, is supporting the Minister of Innovation, Science and Industry, Navdeep Bains. That would suggest a ‘junior’ position wouldn’t it? If you look closely at the Minister of Digital Services’ mandate letter, you’ll see the Minister is almost always supporting another minister.

Where the Phoenix Pay System is concerned, the Minister of Digital Services is supporting the Minister of Public Services and Procurement, the previously mentioned rookie MP and rookie Cabinet member, Anita Anand. Interestingly, the employees’ union, PSAC, has decided (as of a November 20, 2019 news release) to ramp up its ad campaign regarding the Phoenix Pay System and its bargaining issues by targeting the Prime Minister and the new President of the Treasury Board, Jean-Yves Duclos. Guess whose mandate letter makes no mention of Phoenix (December 13, 2019 mandate letter for the President of the Treasury Board).

Open government, eh?

Putting a gift bow on a pile of manure doesn’t turn it into a gift (for most people, anyway) and calling your government open and/or transparent doesn’t necessarily make it so even when you amend your Access to Information Act to make it more accessible (August 22, 2019 Digital Government news release by Ruth Naylor).

One of the Liberal government’s most heavily publicized ‘open’ initiatives was the lifting of the muzzles put on federal scientists in the Environment and Natural Resources ministries. Those muzzles were put into place by a Conservative government and the 2015 Liberal government gained a lot of political capital from its actions. No one seemed to remember that Health Canada also had been muzzled. That muzzle had been put into place by one of the Liberal governments preceding the Conservative one. To date there is no word as to whether or not that muzzle has ever been lifted.

However, even in the ministries where the muzzles were lifted, it seems scientists didn’t feel free to speak even many months later (from a Feb 21, 2018 article by Brian Owens for Science),

More than half of government scientists in Canada—53%—do not feel they can speak freely to the media about their work, even after Prime Minister Justin Trudeau’s government eased restrictions on what they can say publicly, according to a survey released today by a union that represents more than 16,000 federal scientists.

That union—the Professional Institute of the Public Service of Canada (PIPSC) based in Ottawa—conducted the survey last summer, a little more than a year and a half into the Trudeau government. It followed up on a similar survey the union released in 2013 at the height of the controversy over the then-Conservative government’s reported muzzling of scientists by preventing media interviews and curtailing travel to scientific conferences. The new survey found the situation much improved—in 2013, 90% of scientists felt unable to speak about their work. But the union says more work needs to be done. “The work needs to be done at the department level,” where civil servants may have been slow to implement political directives, PIPSC President Debi Daviau said. ”We need a culture change that promotes what we have heard from ministers.”

I found this a little chilling (from the PIPSC Defrosting Public Science; a 2017 survey of federal scientists webpage),

To better illustrate this concern, in 2013, The Big Chill revealed that 86% of respondents feared censorship or retaliation from their department or agency if they spoke out about a departmental decision or action that, based on their scientific knowledge, could bring harm to the public interest. In 2017, when asked the same question, 73% of respondents said they would not be able to do so without fear of censorship or retaliation – a mere 13% drop.

It’s possible things have improved but while the 2018 Senate report did not focus on scientists, it did highlight issues with the government’s openness and transparency or in their words: “… a culture that plays down bad news and avoids responsibility.” It seems the Senate is not the only group with concerns about government culture; so do the government’s employees (the scientists, anyway).

The other science commentary

I can’t find any commentary or editorials about the latest ministerial changes or the mandate letters on the Canadian Science Policy Centre website so was doubly pleased to find this December 6, 2019 commentary by Creso Sá for University Affairs,

The recently announced Liberal cabinet brings what appear to be cosmetic changes to the science file. Former Science Minister Kirsty Duncan is no longer in it, which sparked confusion among casual observers who believed that the elimination of her position signalled the termination of the science ministry or the downgrading of the science agenda. In reality, science was and remains part of the renamed Ministry of Innovation, Science, and (now) Industry (rather than Economic Development), where Minister Navdeep Bains continues at the helm.

Arguably, these reactions show that appearances have been central [emphasis mine] to the modus operandi of this government. Minister Duncan was an active, and generally well-liked, champion for the Trudeau government’s science platform. She carried the torch of team science over the last four years, becoming vividly associated with the launch of initiatives such as the Fundamental Science Review, the creation of the chief science advisor position, and the introduction of equity provisions in the Canada Research Chairs program. She talked a good talk, but her role did not in fact give her much authority to change the course of science policy in the country. From the start, her mandate was mostly defined around building bridges with members of cabinet, which was likely good experience for her new role of deputy house leader.

Upon the announcement of the new cabinet, Minister Bains took to Twitter to thank Dr. Duncan for her dedication to placing science in “its rightful place back at the centre of everything our government does.” He indicated that he will take over her responsibilities, which he was already formally responsible for. Presumably, he will now make time to place science at the centre of everything the government does.

This kind of sloganeering has been common [emphasis mine] since the 2015 campaign, which seems to be the strategic moment the Liberals can’t get out of. Such was the real and perceived hostility of the Harper Conservatives to science that the Liberals embraced the role of enlightened advocates. Perhaps the lowest hanging fruit their predecessors left behind was the sheer absence of any intelligible articulation of where they stood on the science file, which the Liberals seized upon with gusto. Virtue signalling [emphasis mine] became a first line of response.

When asked about her main accomplishments over the past year as chief science advisor at the recent Canadian Science Policy Conference in Ottawa, Mona Nemer started with the creation of a network of science advisors across government departments. Over the past four years, the government has indeed not been shy about increasing the number of appointments with “science” in their job titles. That is not a bad thing. We just do not hear much about how “science is at the centre of everything the government does.” Things get much fuzzier when the conversation turns to the bold promises of promoting evidence-based decision making that this government has been vocal about. Queried on how her role has impacted policy making, Dr. Nemer suggested the question should be asked to politicians. [emphasis mine]

I’m tempted to describe the ‘Digital Government’ existence and portfolio as virtue signalling.

Finally

There doesn’t seem to be all that much government interest in science or, even, technology for that matter. We have a ‘junior’ Minister of Science disappear so that science can become part of all the ministries. Frankly, I wish that science were integrated throughout all the ministries but when you consider the government culture, this move more easily lends itself to even less responsibility being taken by anyone. Take another look at the Canada’s Chief Science Advisor’s comment: “Queried on how her role has impacted policy making, Dr. Nemer suggested the question should be asked to politicians.” Meanwhile, we get a ‘junior Minister of Digital Government whose portfolio has the potential to affect Canadians of all ages and resident in Canada or not.

A ‘junior’ minister is not necessarily evil as Sá points out but I would like to see some indication that efforts are being made to shift the civil service culture and the attitude about how the government conducts its business and that the Minister of Digital Government will receive the resources and the respect she needs to do her job. I’d also like to see some understanding of how catastrophic a wrong move has already been and could be in the future along with options for how citizens are going to be making their way through this brave new digital government world and some options for fixing problems, especially the catastrophic ones.

*December 30, 2019 correction: After Scott Brison left his position as President of the Treasury Board and Minister of Digital Government in January 2019, Jane Philpott held the two positions until March 2019 when she left the Liberal Party. Carla Quatrough was acting head from March 4 – March 18, 2019 when Joyce Murray was appointed to the two positions which she held for eight months until November 2019 when, as I’ve noted, the ‘Minister of Digital Government’ was split from the ‘President of the Treasury Board’ appointment.

ETA January 28, 2020: The Canadian Broadcasting Corporation (CBC) has an update on the Phoenix Pay System situation in a January 28, 2020 posting (supplied by The Canadian Press),

More than 98,000 civil servants may still owe the federal government money after being overpaid through the disastrous Phoenix pay system.

… the problems persist, despite the hiring of hundreds of pay specialists to work through a backlog of system errors.

The public service pay centre was still dealing with a backlog of about 202,000 complaints as of Dec. 24 [2019], down from 214,000 pay transactions that went beyond normal workload in November [2019].

The medical community and art/science: two events in Canada in November 2019

This time it’s the performing arts. I have one theatre and psychiatry production in Toronto and a music and medical science event in Vancouver.

Toronto’s Here are the Fragments opening on November 19, 2019

From a November 2, 2019 ArtSci Salon announcement (received via email),

An immersive theatre experience inspired by the psychiatric writing of Frantz Fanon

Here are the Fragments.
Co-produced by The ECT Collective and The Theatre Centre
November 19-December 1, 2019
Tickets: Preview $17 | Student/senior/arts worker $22 | Adult $30
Service charges may apply
Book 416-538-0988 | PURCHASE ONLINE

An immigrant psychiatrist develops psychosis and then schizophrenia. He walks a long path towards reconnection with himself, his son, and humanity.

Walk with him.

Within our immersive design (a fabric of sound, video, and live actors) lean in close to the possibilities of perceptual experience.

Schizophrenics ‘hear voices’. Schizophrenics fear loss of control over their own thoughts and bodies. But how does any one of us actually separate internal and external voices? How do we trust what we see or feel? How do we know which voices are truly our own?

Within the installation find places of retreat from chaos. Find poetry. Find critical analysis.

Explore archival material, Fanon’s writings and contemporary interviews with psychiatrists, neuroscientists, artists, and people living with schizophrenia, to reflect on the relationships between identity, history, racism and mental health.

I was able to find out more in a November 6, 2019 article at broadwayworld.com (Note: Some of this is repetitive),

How do we trust what we see or feel? How do we know which voices are truly our own? THE THEATRE CENTRE and THE ECT COLLECTIVE are proud to Co-produce HERE ARE THE FRAGMENTS., an immersive work of theatre written by Suvendrini Lena, Theatre Centre Residency artist and CAMH [ Centre for Addiction and Mental Health] Neurologist. Based on the psychiatric writing of famed political theorist Frantz Fanon and combining narratives, sensory exploration, and scientific and historical analysis, HERE ARE THE FRAGMENTS. reflects on the relationships between identity, history, racism, and mental health. FRAGMENTS. will run November 19 to December 1 at The Theatre Centre (Opening Night November 21).

HERE ARE THE FRAGMENTS. consists of live performances within an interactive installation. The plot, told in fragments, follows a psychiatrist early in his training as he develops psychosis and ultimately, treatment resistant schizophrenia. Eduard, his son, struggles to connect with his father, while the young man must also make difficult treatment decisions.

The Theatre Centre’s Franco Boni Theatre and Gallery will be transformed into an immersive interactive installation. The design will offer many spaces for exploration, investigation, and discovery, bringing audiences into the perceptual experience of Schizophrenia. The scenes unfold around you, incorporating a fabric of sound, video, and live actors. Amidst the seeming chaos there will also be areas of retreat; whispering voices, Fanon’s own books, archival materials, interviews with psychiatrists, neuroscientists, and people living with schizophrenia all merge to provoke analysis and reflection on the intersection of racism and mental health.

Suvendrini Lena (Writer) is a playwright and neurologist. She works as the staff neurologist at the Centre for Addiction and Mental Health and at the Centre for Headache at Women’s College Hospital [Toronto]. She is an Assistant Professor of Psychiatry and Neurology at the University of Toronto where she teaches medical students, residents, and fellows. She also teaches a course called Staging Medicine, a collaboration between The Theatre Centre and University of Toronto Postgraduate Medical Education.

Frantz Fanon (1925-1961), was a French West Indian psychiatrist, political philosopher, revolutionary, and writer, whose works are influential in the fields of post-colonial studies, critical theory, and Marxism. Fanon published numerous books, including Black Skin, White Masks (1952) and The Wretched of the Earth (1961).

In addition to performances, The Theatre Centre will host a number of panels and events. Highlights include a post-show talkback with Ngozi Paul (Development Producer, Artist/Activist) and Psychiatrist Collaborator Araba Chintoh on November 22. Also of note is Our Patients and Our Selves: Experiences of Racism Among Health Care Workers with facilitator Dr. Fatimah Jackson-Best of Black Health Alliance on November 23rd and Fanon Today: A Creative Symposium on November 24th, a panel, reading, and creative discussion featuring David Austin, Frank Francis, Doris Rajan and George Elliot Clarke [formerly Toronto’s Poet Laureate and Canadian Parliamentary Poet Laureate; emphasis and link mine].

You can get more details and a link for ticket purchase here.

Sounds and Science: Vienna meets Vancouver on November 30, 2019

‘Sounds and Science’ originated at the Medical University of Vienna (Austria) as the November 6, 2019 event posting on the University of British Columbia’s (UBC) Faculty of Medicine website,

The University of British Columbia will host the first Canadian concert bringing leading musical talents of Vienna together with dramatic narratives from science and medicine.

“Sounds and Science: Vienna Meets Vancouver” is part of the President’s Concert Series, to be held Nov. 30, 2019 on UBC campus. The event is modeled on a successful concert series launched in Austria in 2014, in cooperation with the Medical University of Vienna.

“Basic research tends to always stay within its own box, yet research is telling the most beautiful stories,” says Dr. Josef Penninger, director of UBC’s Life Sciences Institute, a professor of medical genetics and a Canada 150 Chair. “With this concert, we are bringing science out of the ivory tower, using the music of great composers such as Mozart, Schubert or Strauss to transport stories of discovery and insight into the major diseases that affected the composers themselves, and continue to have a significant impact on our society.”

Famous composers of the past are often seen as icons of classical music, but in fact, they were human beings, living under enormous physical constraints – perhaps more than people today, according to Dr. Manfred Hecking, an associate professor of internal medicine at the Medical University of Vienna.

“But ‘Sounds and Science’ is not primarily about suffering and disease,” says Dr. Hecking, a former member of the Vienna Philharmonic Orchestra who will be playing double bass during the concert. “It is a fun way of bringing music and science together. Combining music and thought, we hope that we will reach the attendees of the ‘Sounds and Science’ concert in Vancouver on an emotional, perhaps even personal level.”

A showcase for Viennese music, played in the tradition of the Vienna Philharmonic by several of its members, as well as the world-class science being done here at UBC, “Sounds and Science” will feature talks by UBC clinical and research faculty, including Dr. Penninger. Their topics will range from healthy aging and cancer research to the historical impact of bacterial infections.

Combining music and thought, we hope that we will reach the attendees of the ‘Sounds and Science’ concert in Vancouver on an emotional, perhaps even personal level.
Dr. Manfred Hecking

Faculty speaking at “Sounds and Science” will be:
Dr. Allison Eddy, professor and head, department of pediatrics, and chief, pediatric medicine, BC Children’s Hospital and BC Women’s Hospital;
Dr. Troy Grennan, clinical assistant professor, division of infectious diseases, UBC faculty of medicine;
Dr. Poul Sorensen, professor, department of pathology and laboratory medicine, UBC faculty of medicine; and
Dr. Roger Wong, executive associate dean, education and clinical professor of geriatric medicine, UBC faculty of medicine
UBC President and Vice-Chancellor Santa J. Ono and Vice President Health and Dr. Dermot Kelleher, dean, faculty of medicine and vice-president, health at UBC will also speak during the evening.

The musicians include two outstanding members of the Vienna Philharmonic – violinist Prof. Günter Seifert and violist-conductor Hans Peter Ochsenhofer, who will be joined by violinist-conductor Rémy Ballot and double bassist Dr. Manfred Hecking, who serves as a regular substitute in the orchestra.

For those in whose lives intertwine music and science, the experience of cross-connection will be familiar. For Dr. Penninger, the concert represents an opportunity to bring the famous sound of the Vienna Philharmonic to UBC and British Columbia, to a new audience. “That these musicians are coming here is a fantastic recognition and acknowledgement of the amazing work being done at UBC,” he says.

“Like poetry, music is a universal language that all of us immediately understand and can relate to. Science tells the most amazing stories. Both of them bring meaning and beauty to our world.”

“Sounds and Science” – Vienna Meets Vancouver is part of the President’s Concert Series | November 30, 2019 on campus at the Old Auditorium from 6:30 to 9:30 p.m.

To learn more about the Sounds and Science concert series hosted in cooperation with the Medical University of Vienna, visit www.soundsandscience.com.

I found more information regarding logistics,

Saturday, November 30, 2019
6:30 pm
The Old Auditorium, 6344 Memorial Road, UBC

Box office and Lobby: Opens at 5:30 pm (one hour prior to start of performance)
Old Auditorium Concert Hall: Opens at 6:00 pm

Sounds
Günter Seifert  VIOLIN
Rémy Ballot VIOLIN
Hans Peter Ochsenhofer VIOLA
Manfred Hecking DOUBLE BASS

Science
Josef Penninger GENETICS
Manfred Hecking INTERNAL MEDICINE
Troy Grennan INFECTIOUS DISEASE
Poul Sorensen PATHOLOGY & LABORATORY MEDICINE
Allison Eddy PEDIATRICS
Roger Wong GERIATRICS

Tickets are also available in person at UBC concert box-office locations:
– Old Auditorium
– Freddie Wood Theatre
– The Chan Centre for the Performing Art

General admission: $10.00
Free seating for UBC students
Purchase tickets for both President’s Concert Series events to make it a package, and save 10% on both performances

Transportation
Public and Bike Transportation
Please visit Translink for bike and transit information.
Parking
Suggested parking in the Rose Garden Parkade.

Buy Tickets

The Sounds and Science website has a feature abut the upcoming Vancouver concert and it offers a history dating from 2008,

MUSIC AND MEDICINE

The idea of combining music and medicine into the “Sounds & Science” – scientific concert series started in 2008, when the Austrian violinist Rainer Honeck played Bach’s Chaconne in d-minor directly before a keynote lecture, held by Nobel laureate Peter Doherty, at the Austrian Society of Allergology and Immunology’s yearly meeting in Vienna. The experience at that lecture was remarkable, truly a special moment. “Sounds & Science” was then taken a step further by bringing several concepts together: Anton Neumayr’s medical histories of composers, John Brockman’s idea of a “Third Culture” (very broadly speaking: combining humanities and science), and finally, our perception that science deserves a “Red Carpet” to walk on, in front of an audience. Attendees of the “Sounds & Science” series have also described that music opens the mind, and enables a better understanding of concepts in life and thereby science in general. On a typical concert/lecture, we start with a chamber music piece, continue with the pathobiography of the composer, go back to the music, and then introduce our main speaker, whose talk should be genuinely understandable to a broad, not necessarily scientifically trained audience. In the second half, we usually try to present a musical climax. One prerequisite that “Sounds & Science” stands for, is the outstanding quality of the principal musicians, and of the main speakers. Our previous concerts/lectures have so far covered several aspects of medicine like “Music & Cancer” (Debussy, Brahms, Schumann), “Music and Heart” (Bruckner, Mahler, Wagner), and “Music and Diabetes” (Bach, Ysaÿe, Puccini). For many individuals who have combined music and medicine or music and science inside of their own lives and biographies, the experience of a cross-connection between sounds and science is quite familiar. But there is also this “fun” aspect of sharing and participating, and at the “Sounds & Science” events, we usually try to ensure that the event location can easily be turned into a meeting place.

At a guess, Science and Sounds started informally in 2008 and became a formal series in 2014.

There is a video but it’s in German. It’s enjoyable viewing with beautiful music but unless you have German language skills you won’t get the humour. Also it runs for over 9 minutes (a little longer than most of videos you’ll find here on FrogHeart),

Enjoy!