Tag Archives: water purification

Gold nanoparticles as catalysts for clear water and hydrogen production

The research was published online May 2014 and in a July 2014 print version,  which seems a long time ago now but there’s a renewed interest in attracting attention for this work. A Dec. 17, 2014 news item on phys.org describes this proposed water purification technology from Singapore’s A*STAR (Agency for Science Technology and Research), Note: Links have been removed,

A new catalyst could have dramatic environmental benefits if it can live up to its potential, suggests research from Singapore. A*STAR researchers have produced a catalyst with gold-nanoparticle antennas that can improve water quality in daylight and also generate hydrogen as a green energy source.

This water purification technology was developed by He-Kuan Luo, Andy Hor and colleagues from the A*STAR Institute of Materials Research and Engineering (IMRE). “Any innovative and benign technology that can remove or destroy organic pollutants from water under ambient conditions is highly welcome,” explains Hor, who is executive director of the IMRE and also affiliated with the National University of Singapore.

A Dec. 17, 2014 A*STAR research highlight, which originated the news item, describes the photocatalytic process the research team developed and tested,

Photocatalytic materials harness sunlight to create electrical charges, which provide the energy needed to drive chemical reactions in molecules attached to the catalyst’s surface. In addition to decomposing harmful molecules in water, photocatalysts are used to split water into its components of oxygen and hydrogen; hydrogen can then be employed as a green energy source.

Hor and his team set out to improve an existing catalyst. Oxygen-based compounds such as strontium titanate (SrTiO3) look promising, as they are robust and stable materials and are suitable for use in water. One of the team’s innovations was to enhance its catalytic activity by adding small quantities of the metal lanthanum, which provides additional usable electrical charges.

Catalysts also need to capture a sufficient amount of sunlight to catalyze chemical reactions. So to enable the photocatalyst to harvest more light, the scientists attached gold nanoparticles to the lanthanum-doped SrTiO3 microspheres (see image). These gold nanoparticles are enriched with electrons and hence act as antennas, concentrating light to accelerate the catalytic reaction.

The porous structure of the microspheres results in a large surface area, as it provides more binding space for organic molecules to dock to. A single gram of the material has a surface area of about 100 square meters. “The large surface area plays a critical role in achieving a good photocatalytic activity,” comments Luo.

To demonstrate the efficiency of these catalysts, the researchers studied how they decomposed the dye rhodamine B in water. Within four hours of exposure to visible light 92 per cent of the dye was gone, which is much faster than conventional catalysts that lack gold nanoparticles.

These microparticles can also be used for water splitting, says Luo. The team showed that the microparticles with gold nanoparticles performed better in water-splitting experiments than those without, further highlighting the versatility and effectiveness of these microspheres.

The researchers have provided an illustration of the process,

Improved photocatalyst microparticles containing gold nanoparticles can be used to purify water. © 2014 A*STAR Institute of Materials Research and Engineering

Improved photocatalyst microparticles containing gold nanoparticles can be used to purify water.
© 2014 A*STAR Institute of Materials Research and Engineering

Here’s a link to and a citation for the research paper,

Novel Au/La-SrTiO3 microspheres: Superimposed Effect of Gold Nanoparticles and Lanthanum Doping in Photocatalysis by Guannan Wang, Pei Wang, Dr. He-Kuan Luo, and Prof. T. S. Andy Hor. Chemistry – An Asian Journal Volume 9, Issue 7, pages 1854–1859, July 2014. Article first published online: 9 MAY 2014 DOI: 10.1002/asia.201402007

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

This article is behind a paywall.

Earth Day, Water Day, and every day

I’m blaming my confusion on the American Chemical Society (ACS) which seemed to be celebrating Earth Day on April 15, 2014 as per its news release highlighting their “Chemists Celebrate Earth Day” video series  while in Vancouver, Canada, we’re celebrating it on April 26, 2014 and elsewhere it seems to be on April 20, this year. Regardless, here’s more about how chemist’s are celebrating from the ACS news release,

Water is arguably the most important resource on the planet. In celebration of Earth Day, the American Chemical Society (ACS) is showcasing three scientists whose research keeps water safe, clean and available for future generations. Geared toward elementary and middle school students, the “Chemists Celebrate Earth Day” series highlights the important work that chemists and chemical engineers do every day. The videos are available at http://bit.ly/CCED2014.

The series focuses on the following subjects:

  • Transforming Tech Toys- Featuring Aydogan Ozcan, Ph.D., of UCLA: Ozcan takes everyday gadgets and turns them into powerful mobile laboratories. He’s made a cell phone into a blood analyzer and a bacteria detector, and now he’s built a device that turns a cell phone into a water tester. It can detect very harmful mercury even at very low levels.
  • All About Droughts - Featuring Collins Balcombe of the U.S. Bureau of Reclamation: Balcombe’s job is to keep your drinking water safe and to find new ways to re-use the water that we flush away everyday so that it doesn’t go to waste, especially in areas that don’t get much rain.
  • Cleaning Up Our Water – Featuring Anne Morrissey, Ph.D., of Dublin City University: We all take medicines, but did you know that sometimes the medicine doesn’t stay in our bodies? It’s up to Anne Morrissey to figure out how to get potentially harmful pharmaceuticals out of the water supply, and she’s doing it using one of the most plentiful things on the planet: sunlight.

Sadly, I missed marking World Water Day which according to a March 21, 2014 news release I received was being celebrated on Saturday, March 22, 2014 with worldwide events and the release of a new UN report,

World Water Day: UN Stresses Water and Energy Issues 

Tokyo Leads Public Celebrations Around the World

Tokyo — March 21 — The deep-rooted relationships between water and energy were highlighted today during main global celebrations in Tokyo marking the United Nations’ annual World Water Day.

“Water and energy are among the world’s most pre-eminent challenges. This year’s focus of World Water Day brings these issues to the attention of the world,” said Michel Jarraud, Secretary-General of the World Meteorological Organization and Chair of UN-Water, which coordinates World Water Day and freshwater-related efforts UN system-wide.

The UN predicts that by 2030 the global population will need 35% more food, 40% more water and 50% more energy. Already today 768 million people lack access to improved water sources, 2.5 billion people have no improved sanitation and 1.3 billion people cannot access electricity.

“These issues need urgent attention – both now and in the post-2015 development discussions. The situation is unacceptable. It is often the same people who lack access to water and sanitation who also lack access to energy, ” said Mr. Jarraud.

The 2014 World Water Development Report (WWDR) – a UN-Water flagship report, produced and coordinated by the World Water Assessment Programme, which is hosted and led by UNESCO – is released on World Water Day as an authoritative status report on global freshwater resources. It highlights the need for policies and regulatory frameworks that recognize and integrate approaches to water and energy priorities.

WWDR, a triennial report from 2003 to 2012, this year becomes an annual edition, responding to the international community’s expression of interest in a concise, evidence-based and yearly publication with a specific thematic focus and recommendations.

WWDR 2014 underlines how water-related issues and choices impact energy and vice versa. For example: drought diminishes energy production, while lack of access to electricity limits irrigation possibilities.

The report notes that roughly 75% of all industrial water withdrawals are used for energy production. Tariffs also illustrate this interdependence: if water is subsidized to sell below cost (as is often the case), energy producers – major water consumers – are less likely to conserve it.  Energy subsidies, in turn, drive up water usage.

The report stresses the imperative of coordinating political governance and ensuring that water and energy prices reflect real costs and environmental impacts.

“Energy and water are at the top of the global development agenda,” said the Rector of United Nations University, David Malone, this year’s coordinator of World Water Day on behalf of UN-Water together with the United Nations Industrial Development Organization (UNIDO).

“Significant policy gaps exist in this nexus at present, and the UN plays an instrumental role in providing evidence and policy-relevant guidance. Through this day, we seek to inform decision-makers, stakeholders and practitioners about the interlinkages, potential synergies and trade-offs, and highlight the need for appropriate responses and regulatory frameworks that account for both water and energy priorities. From UNU’s perspective, it is essential that we stimulate more debate and interactive dialogue around possible solutions to our energy and water challenges.”

UNIDO Director-General LI Yong, emphasized the importance of water and energy for inclusive and sustainable industrial development.

“There is a strong call today for integrating the economic dimension, and the role of industry and manufacturing in particular, into the global post-2015 development priorities. Experience shows that environmentally sound interventions in manufacturing industries can be highly effective and can significantly reduce environmental degradation. I am convinced that inclusive and sustainable industrial development will be a key driver for the successful integration of the economic, social and environmental dimensions,” said Mr. LI.

Rather unusually, Michael Bergerrecently published two Nanowerk Spotlight articles about water (is there theme, anyone?) within 24 hours of each other. In his March 26, 2014 Spotlight article, Michael Berger focuses on graphene and water remediation (Note: Links have been removed),

The unique properties of nanomaterials are beneficial in applications to remove pollutants from the environment. The extremely small size of nanomaterial particles creates a large surface area in relation to their volume, which makes them highly reactive, compared to non-nano forms of the same materials.

The potential impact areas for nanotechnology in water applications are divided into three categories: treatment and remediation; sensing and detection: and pollution prevention (read more: “Nanotechnology and water treatment”).

Silver, iron, gold, titanium oxides and iron oxides are some of the commonly used nanoscale metals and metal oxides cited by the researchers that can be used in environmental remediation (read more: “Overview of nanomaterials for cleaning up the environment”).

A more recent entrant into this nanomaterial arsenal is graphene. Individual graphene sheets and their functionalized derivatives have been used to remove metal ions and organic pollutants from water. These graphene-based nanomaterials show quite high adsorption performance as adsorbents. However they also cause additional cost because the removal of these adsorbent materials after usage is difficult and there is the risk of secondary environmental pollution unless the nanomaterials are collected completely after usage.

One solution to this problem would be the assembly of individual sheets into three-dimensional (3D) macroscopic structures which would preserve the unique properties of individual graphene sheets, and offer easy collecting and recycling after water remediation.

The March 27, 2014 Nanowerk Spotlight article was written by someone at Alberta’s (Canada) Ingenuity Lab and focuses on their ‘nanobiological’ approach to water remediation (Note: Links have been removed),

At Ingenuity Lab in Edmonton, Alberta, Dr. Carlo Montemagno and a team of world-class researchers have been investigating plausible solutions to existing water purification challenges. They are building on Dr. Montemagno’s earlier patented discoveries by using a naturally-existing water channel protein as the functional unit in water purification membranes [4].

Aquaporins are water-transport proteins that play an important osmoregulation role in living organisms [5]. These proteins boast exceptionally high water permeability (~ 1010 water molecules/s), high selectivity for pure water molecules, and a low energy cost, which make aquaporin-embedded membrane well suited as an alternative to conventional RO membranes.

Unlike synthetic polymeric membranes, which are driven by the high pressure-induced diffusion of water through size selective pores, this technology utilizes the biological osmosis mechanism to control the flow of water in cellular systems at low energy. In nature, the direction of osmotic water flow is determined by the osmotic pressure difference between compartments, i.e. water flows toward higher osmotic pressure compartment (salty solution or contaminated water). This direction can however be reversed by applying a pressure to the salty solution (i.e., RO).

The principle of RO is based on the semipermeable characteristics of the separating membrane, which allows the transport of only water molecules depending on the direction of osmotic gradient. Therefore, as envisioned in the recent publication (“Recent Progress in Advanced Nanobiological Materials for Energy and Environmental Applications”), the core of Ingenuity Lab’s approach is to control the direction of water flow through aquaporin channels with a minimum level of pressure and to use aquaporin-embedded biomimetic membranes as an alternative to conventional RO membranes.

Here’s a link to and a citation for Montemagno’s and his colleague’s paper,

Recent Progress in Advanced Nanobiological Materials for Energy and Environmental Applications by Hyo-Jick Choi and Carlo D. Montemagno. Materials 2013, 6(12), 5821-5856; doi:10.3390/ma6125821

This paper is open access.

Returning to where I started, here’s a water video featuring graphene from the ACS celebration of Earth Day 2014,

Happy Earth Day!

Water desalination by graphene and water purification by sapwood

I have two items about water. The first concerns a new technique from MIT (Massachusetts Institute of Technology) for desalination using graphene. From a Feb. 25, 2014 news release by David Chandler on EurekAlert,

Researchers have devised a way of making tiny holes of controllable size in sheets of graphene, a development that could lead to ultrathin filters for improved desalination or water purification.

The team of researchers at MIT, Oak Ridge National Laboratory, and in Saudi Arabia succeeded in creating subnanoscale pores in a sheet of the one-atom-thick material, which is one of the strongest materials known. …

The concept of using graphene, perforated by nanoscale pores, as a filter in desalination has been proposed and analyzed by other MIT researchers. The new work, led by graduate student Sean O’Hern and associate professor of mechanical engineering Rohit Karnik, is the first step toward actual production of such a graphene filter.

Making these minuscule holes in graphene — a hexagonal array of carbon atoms, like atomic-scale chicken wire — occurs in a two-stage process. First, the graphene is bombarded with gallium ions, which disrupt the carbon bonds. Then, the graphene is etched with an oxidizing solution that reacts strongly with the disrupted bonds — producing a hole at each spot where the gallium ions struck. By controlling how long the graphene sheet is left in the oxidizing solution, the MIT researchers can control the average size of the pores.

A big limitation in existing nanofiltration and reverse-osmosis desalination plants, which use filters to separate salt from seawater, is their low permeability: Water flows very slowly through them. The graphene filters, being much thinner, yet very strong, can sustain a much higher flow. “We’ve developed the first membrane that consists of a high density of subnanometer-scale pores in an atomically thin, single sheet of graphene,” O’Hern says.

For efficient desalination, a membrane must demonstrate “a high rejection rate of salt, yet a high flow rate of water,” he adds. One way of doing that is decreasing the membrane’s thickness, but this quickly renders conventional polymer-based membranes too weak to sustain the water pressure, or too ineffective at rejecting salt, he explains.

With graphene membranes, it becomes simply a matter of controlling the size of the pores, making them “larger than water molecules, but smaller than everything else,” O’Hern says — whether salt, impurities, or particular kinds of biochemical molecules.

The permeability of such graphene filters, according to computer simulations, could be 50 times greater than that of conventional membranes, as demonstrated earlier by a team of MIT researchers led by graduate student David Cohen-Tanugi of the Department of Materials Science and Engineering. But producing such filters with controlled pore sizes has remained a challenge. The new work, O’Hern says, demonstrates a method for actually producing such material with dense concentrations of nanometer-scale holes over large areas.

“We bombard the graphene with gallium ions at high energy,” O’Hern says. “That creates defects in the graphene structure, and these defects are more chemically reactive.” When the material is bathed in a reactive oxidant solution, the oxidant “preferentially attacks the defects,” and etches away many holes of roughly similar size. O’Hern and his co-authors were able to produce a membrane with 5 trillion pores per square centimeter, well suited to use for filtration. “To better understand how small and dense these graphene pores are, if our graphene membrane were to be magnified about a million times, the pores would be less than 1 millimeter in size, spaced about 4 millimeters apart, and span over 38 square miles, an area roughly half the size of Boston,” O’Hern says.

With this technique, the researchers were able to control the filtration properties of a single, centimeter-sized sheet of graphene: Without etching, no salt flowed through the defects formed by gallium ions. With just a little etching, the membranes started allowing positive salt ions to flow through. With further etching, the membranes allowed both positive and negative salt ions to flow through, but blocked the flow of larger organic molecules. With even more etching, the pores were large enough to allow everything to go through.

Scaling up the process to produce useful sheets of the permeable graphene, while maintaining control over the pore sizes, will require further research, O’Hern says.

Karnik says that such membranes, depending on their pore size, could find various applications. Desalination and nanofiltration may be the most demanding, since the membranes required for these plants would be very large. But for other purposes, such as selective filtration of molecules — for example, removal of unreacted reagents from DNA — even the very small filters produced so far might be useful.

“For biofiltration, size or cost are not as critical,” Karnik says. “For those applications, the current scale is suitable.”

Dexter Johnson in a Feb. 26,2014 posting provides some context for and insight into the work (from the Nanoclast blog on the IEEE [Institute of Electrical and Electronics Engineers]), Note: Links have been removed,

About 18 months ago, I wrote about an MIT project in which computer models demonstrated that graphene could act as a filter in the desalination of water through the reverse osmosis (RO) method. RO is slightly less energy intensive than the predominantly used multi-stage-flash process. The hope was that the nanopores of the graphene material would make the RO method even less energy intensive than current versions by making it easier to push the water through the filter membrane.

The models were promising, but other researchers in the field said at the time it was going to be a long road to translate a computer model to a real product.

It would seem that the MIT researchers agreed it was worth the effort and accepted the challenge to go from computer model to a real device as they announced this week that they had developed a method for creating selective pores in graphene that make it suitable for water desalination.

Here’s a link to and a citation for the paper,

Selective Ionic Transport through Tunable Subnanometer Pores in Single-Layer Graphene Membranes by Sean C. O’Hern, Michael S. H. Boutilier, Juan-Carlos Idrobo, Yi Song, Jing Kong, Tahar Laoui, Muataz Atieh, and Rohit Karnik. Nano Lett., Article ASAP DOI: 10.1021/nl404118f Publication Date (Web): February 3, 2014

Copyright © 2014 American Chemical Society

This article is behind a paywall.

The second item is also from MIT and concerns a low-tech means of purifying water. From a Feb. 27, 2014 news item on Azonano,

If you’ve run out of drinking water during a lakeside camping trip, there’s a simple solution: Break off a branch from the nearest pine tree, peel away the bark, and slowly pour lake water through the stick. The improvised filter should trap any bacteria, producing fresh, uncontaminated water.

In fact, an MIT team has discovered that this low-tech filtration system can produce up to four liters of drinking water a day — enough to quench the thirst of a typical person.

In a paper published this week in the journal PLoS ONE, the researchers demonstrate that a small piece of sapwood can filter out more than 99 percent of the bacteria E. coli from water. They say the size of the pores in sapwood — which contains xylem tissue evolved to transport sap up the length of a tree — also allows water through while blocking most types of bacteria.

Co-author Rohit Karnik, an associate professor of mechanical engineering at MIT, says sapwood is a promising, low-cost, and efficient material for water filtration, particularly for rural communities where more advanced filtration systems are not readily accessible.

“Today’s filtration membranes have nanoscale pores that are not something you can manufacture in a garage very easily,” Karnik says. “The idea here is that we don’t need to fabricate a membrane, because it’s easily available. You can just take a piece of wood and make a filter out of it.”

The Feb. 26, 2014 news release on EurekAlert, which originated the news item, describes current filtration techniques and the advantages associated with this new low-tech approach,

There are a number of water-purification technologies on the market today, although many come with drawbacks: Systems that rely on chlorine treatment work well at large scales, but are expensive. Boiling water to remove contaminants requires a great deal of fuel to heat the water. Membrane-based filters, while able to remove microbes, are expensive, require a pump, and can become easily clogged.

Sapwood may offer a low-cost, small-scale alternative. The wood is comprised of xylem, porous tissue that conducts sap from a tree’s roots to its crown through a system of vessels and pores. Each vessel wall is pockmarked with tiny pores called pit membranes, through which sap can essentially hopscotch, flowing from one vessel to another as it feeds structures along a tree’s length. The pores also limit cavitation, a process by which air bubbles can grow and spread in xylem, eventually killing a tree. The xylem’s tiny pores can trap bubbles, preventing them from spreading in the wood.

“Plants have had to figure out how to filter out bubbles but allow easy flow of sap,” Karnik observes. “It’s the same problem with water filtration where we want to filter out microbes but maintain a high flow rate. So it’s a nice coincidence that the problems are similar.”

The news release also describes the experimental procedure the scientists followed (from the news release),

To study sapwood’s water-filtering potential, the researchers collected branches of white pine and stripped off the outer bark. They cut small sections of sapwood measuring about an inch long and half an inch wide, and mounted each in plastic tubing, sealed with epoxy and secured with clamps.

Before experimenting with contaminated water, the group used water mixed with red ink particles ranging from 70 to 500 nanometers in size. After all the liquid passed through, the researchers sliced the sapwood in half lengthwise, and observed that much of the red dye was contained within the very top layers of the wood, while the filtrate, or filtered water, was clear. This experiment showed that sapwood is naturally able to filter out particles bigger than about 70 nanometers.

However, in another experiment, the team found that sapwood was unable to separate out 20-nanometer particles from water, suggesting that there is a limit to the size of particles coniferous sapwood can filter.

Finally, the team flowed inactivated, E. coli-contaminated water through the wood filter. When they examined the xylem under a fluorescent microscope, they saw that bacteria had accumulated around pit membranes in the first few millimeters of the wood. Counting the bacterial cells in the filtered water, the researchers found that the sapwood was able to filter out more than 99 percent of E. coli from water.

Karnik says sapwood likely can filter most types of bacteria, the smallest of which measure about 200 nanometers. However, the filter probably cannot trap most viruses, which are much smaller in size.

The researchers have future plans (from the news release),

Karnik says his group now plans to evaluate the filtering potential of other types of sapwood. In general, flowering trees have smaller pores than coniferous trees, suggesting that they may be able to filter out even smaller particles. However, vessels in flowering trees tend to be much longer, which may be less practical for designing a compact water filter.

Designers interested in using sapwood as a filtering material will also have to find ways to keep the wood damp, or to dry it while retaining the xylem function. In other experiments with dried sapwood, Karnik found that water either did not flow through well, or flowed through cracks, but did not filter out contaminants.

“There’s huge variation between plants,” Karnik says. “There could be much better plants out there that are suitable for this process. Ideally, a filter would be a thin slice of wood you could use for a few days, then throw it away and replace at almost no cost. It’s orders of magnitude cheaper than the high-end membranes on the market today.”

Here’s a link to and a citation for the paper,

Water Filtration Using Plant Xylem by Michael S. H. Boutilier, Jongho Lee, Valerie Chambers, Varsha Venkatesh, & Rohit Karnik. PLOS One Published: February 26, 2014 DOI: 10.1371/journal.pone.0089934

This paper is open access.

One final observation, two of the researchers listed as authors on the graphene/water desalination paper are also listed on the low-tech sapwood paper (Michael S. H. Boutilier & Rohit Karnik).

Grand Challenges Canada funds 83 projects to improve global health

For the third year in a row (as per my Dec. 22, 2011 posting and my Nov. 22, 2012 posting), I’m featuring Grand Challenges Canada funding for its ‘Stars in Global Health’ programme . From the Grand Challenges Canada (GCC) Nov. 21, 2013 news release,

Imaginative: 83 Bold Innovations to Improve Global Health Receive Grand Challenges Canada Funding

Among novel ideas to reduce disease, save lives in developing world:
Diagnostic diapers to detect deadly rotavirus; Rolling water barrel;
Special yogurt offsets pesticides, heavy metals, toxins in food;
Inventive shoe, boot material releases bug repellent when walking

50 innovators from low- and middle-income countries,
plus 33 from Canada, share $9.3 million in seed grants

Grand Challenges Canada, funded by the Government of Canada, today extends seed grants of $100,000 each to 83 inventive new ideas for addressing health problems in resource-poor countries.

The Grand Challenges Canada “Stars in Global Health” program seeks breakthrough and affordable innovations that could transform the way disease is treated in the developing world — innovations that may benefit the health of developed world citizens as well.

Of the 83 grants announced today, 50 are given to innovators in 15 low- and middle-income nations worldwide and 33 to Canadian-originated projects, to be implemented in a total of 30 countries throughout the developing world.

“Innovation powers development leading to better health and more jobs. I feel proud that Canada, through Grand Challenges Canada, has supported almost 300 bold ideas to date in our Stars in Global Health program,” says Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada.  “This is one of the largest pipelines of innovations in global health in the world today.”

Says the Honourable Christian Paradis, Canadian Minister of International Development and Minister for La Francophonie: “Grand Challenges Canada’s portfolio of projects shows how innovators with bold ideas have the potential to make a big impact on global health.  By connecting game-changing ideas with some of the most pressing global health challenges, these projects will lead to sustainable and affordable health solutions in low- and middle-income countries.”

The portfolio of 83 creative, out-of-the-box ideas, selected through independent peer review from 451 applications, includes projects submitted by social entrepreneurs, private sector companies and non-government organizations as well as university researchers.  Among them:

Diagnostics

  • A simple, portable, dry, yeast-based blood screening test (Belize, Jamaica).  WHO estimates almost half of 46 million blood donations in low-income countries are inadequately tested;  in Africa up to 10% of new HIV infections are caused by transfusions.  A University of Toronto-developed yeast-based blood screening tool will detect combinations of diseases. Like baking yeast, it can be stored dry, and can be grown locally with minimal equipment and training, improving accessibility in rural areas.
  • A bedside, Litmus paper-like test to detect bronchitis (Brazil, India). Being pioneered at McMaster University with international collaborators, a simple sputum test will detect infectious and allergic bronchitis in adults and children, reducing mis-diagnosis in developing countries and saving resources: time, steroids, antibiotics.

Water, sanitation, hygiene and general health

  • Special yogurts formulated to offset the harm to health caused by heavy metals, pesticides and other toxics in food (Africa).  Between 2006-2009 in Nairobi, only 17% of the total maize sampled and 5% of feed was fit for human and animal consumption respectively. University of Western Ontario researchers have developed novel yogurts containing a bacteria that, in the stomach, sequesters certain toxins and heavy metals and degrades some pesticides.
  • Addressing arsenic-laced groundwater. In Bangladesh, 1 in 5 deaths (600,000 per year) occur due to groundwater arsenic, dubbed by WHO as the largest mass poisoning in history, with some 77 million people at risk.  Project 1) Toronto-based PurifAid will deploy new filtration units via franchised villagers who will filter and deliver purified water, perform maintenance, acquire new filters and dispose of old ones, which can be used to produce biofuels.  Project 2) A project based at the University of Calgary, meanwhile, will work to increase the use of Western Canadian lentils in Bangladeshi diets.  The crop is rich in selenium, which can decrease arsenic levels and improve health.
  • “WaterWheel” (India, Kenya, Mongolia).  This simple, innovative device from India is a wheeled water container that enables the collection and transport of 3 to 5 times as much water as usual per trip, as well as hygienic storage, saving valuable time for productive activities and improving health.

Malaria

  • A vaccine based on a newly-discovered antibody in men that prevents malaria infection in the placenta (Benin, Colombia).  Colombian men exposed to malaria are found to have antibodies that can prevent infection in the placenta of a pregnant woman. This University of Alberta finding forms the basis for developing a novel vaccine against several forms of malaria, which cause 10,000 maternal deaths and 200,000 stillbirths annually.
  • Insect-repellent clothing, footwear and wall plaster (East Africa).  1) In Tanzania, the Africa Technical Research Institute will lead the design and manufacture of attractive, affordable insecticide-treated clothing while 2) the Ifakara Health Institute will develop anti-mosquito footwear material that slowly releases repellents from the friction of walking.  A key advantage: no compliance or change in habits required.  3) Uganda’s Med Biotech Laboratories, meanwhile, will produce a colorful, insecticide-infused ‘plaster’ for the outside walls of African village homes.

Maternal and child health

  • Mothers Telling Mothers: improving maternal health through storytelling (Uganda).  Work by Twezimbe Development Association has found that stories told by mothers in their own words and reflecting shared realities are most likely to increase the number of moms seeking skilled health care, and convince policymakers to improve healthcare access.  This project will capture 3 to 5 minutes stories to be shared through digital media platforms and health clinics.

Mobile technology

  • Digital African Health Library (Sub-Saharan Africa).  The University of Calgary-led project is creating an app to support bedside care by medical doctors in Africa: a smartphone-accessible resource providing evidence-based, locally-relevant decision support and health information.  A pilot involving 65 doctors in Rwanda showed point of care answers to patient questions more than tripled to 43%, with self-reported improvement in patient outcomes.

Health care

  • Simple sticker helps track clean surfaces in healthcare facilities (Philippines).  WHO estimates that 10% to 30% of all patients in developing country health care facilities acquire an infection.   An innovative sticker for hospital surfaces developed by Lunanos Inc. changes colour when a cleaner is applied and fades color after a predetermined period of time, helping staff track and ensure cleanliness of equipment and other frequently touched surfaces.
  • “Mystery clients” to assess and improve quality of TB care (India).  India accounts for 25% of global tuberculosis (TB) incidence.  To evaluate variations in practice quality, and identify ways to improve TB management in India, this project, led by Canada’s McGill University, will send researchers into clinics posing as a patient with standard TB symptoms.  The project builds on earlier work related to angina, asthma and dysentery, which revealed incorrect diagnoses and treatment.

And many more.

A complete set of 83 short project descriptions, with links to additional project details, available photos / video, and local contact information, is available in the full news release online here: http://bit.ly/HOLt5b

Here’s a video for the one of the projects (filtering arsenic out of Bangladesh’s water),

I chose this project somewhat haphazardly. It caught my attention as I have written more than once about purification efforts and as it turns out, this is a Canada-based project (with a Bangladeshi partner, BRAC) from the University of Toronto.

You may have heard the video’s narrator mention scotch whiskey, here’s why (from the YouTube page hosting the project video,page),

We plan to roll out a new generation of filtration units which run on an organic by-product of the beverage industry. The units address many of the failings of existing devices (they require no power or chemicals and are very low maintenance).

This project gets still more interesting (from the full project description page),

Device for the Remediation and Attenuation of Multiple Pollutants (DRAM) removes 95% of arsenic from contaminated water within 5 minutes of exposure. With an estimated 600,000 deaths directly attributable to arsenic poisoning every year, these units hold the potential to save millions of lives. Existing solutions are too complicated and suffer from significant usability issues (2012 UNICEF study).

We will deploy our units through a franchise business model. [emphasis mine] Local villagers will filter and deliver purified water, perform maintenance, acquire new media, and dispose spent media. The current market leader, the Sono Filter, has less than 20% uptake (according to UNICEF). DRAM costs only 25% of this solution, has lower maintenance requirements (4-6 month media cycle vs. 2 week media cycle), higher durability, and can be retrofitted onto existing tube wells villagers use thereby requiring no behavior change. The spent media (which must be replaced every 4-6 months) can be used to produce biofuels, giving PurifAid a decisive capability over competitors.

With the assistance of our local partner BRAC (ranked #1 on Global Journal’s list of top NGOs in 2012) we will retrofit our units onto existing tubewells. Contaminated water is pumped from the tubewell into the unit where it passes into the bottom of the unit, rising up through a bed of the organic filter media, binding the arsenic. Clean water is displaced and forced out of the top of the unit and out through the built-in tap. Our community based solution will begin with a proof-of-concept installation in the Mujibnagar District (pop. 1.3 million). BRAC will assist in testing our filter water quality on the ground and these results will be used to obtain regulatory approval for our technology. We will then operationalize our community-run DRAM systems. A council of local stakeholders will nominate prospective franchisees amongst villagers. These villagers will replace filter media in 4 month intervals and order annual delivery of new media. We are securing partnerships with nearby distilleries to locally source the filter media. [emphasis mine] Disposal will be handled by a local caretaker who will store spent media in bulk before transferring it for use as biofuel. Caretaker salary, media sourcing, and delivery costs will be paid by charging a levy on customer households. PurifAid will monitor behavioural and health indicators to ascertain DRAM’s immediate and long-term impact. To this end PurifAid has partnered with Ashalytics, a start-up global health analytics company, to report operational issues, measure impact, and communicate important metrics to key staff and stakeholders via mobile phones. This results in an environmentally-friendly value chain that uses beverage industry waste, maximizing positive impact. If the Bangladesh installations are a success then this system can be introduced across the Indian subcontinent and in west Africa, where arsenic in groundwater poses a serious health problem. DRAM has the potential to improve the lives of millions globally.

After 18 months we envisage having installed 15 DRAM systems supplying 45 liters of purified water per day to 2,700 households. In order to ensure maintenance, 15 paid caretakers will operate the pumps and a driver will supply the caretakers with fresh media every 4-6 months. Biannually, new bulk media will be provided to storage unit in the village, spent media will in turn be taken to a plant and converted to biofuel. Villagers will invest collectively to purchase, install and operate DRAM on pre-existing tube wells – thus no behavioral changes needed.

Our filters employ a new water filtration technology. Our franchise model involves social and business innovation, empowering communities to manage their own water treatment under the stewardship of a local partner that manages 17 social businesses with combined annual revenues of $93m in 2011.

(Aside: Don’t they ask for a ‘dram’ of whiskey in the movies?) This project is intended to do more than purify water; it’s designed to create jobs. Bravo!

Now back to the news release for details about the countries and agencies involved,

The global portfolio of grants, broken down by region and country:

30 projects based in 6 African countries (16 in Kenya, 5 in Tanzania, 5 in Uganda, 2 in Nigeria and 1 each in Senegal and Ghana)
17 projects based in 7 countries in Asia (7 in India, 2 in Pakistan 4 in Thailand and 1 each in Bangladesh, Cambodia, Mongolia and the Philippines)
Two projects based in South America (Peru) and one in Europe (Armenia)
33 projects based in 11 Canadian cities (14 in Toronto, 3 each in Calgary, Montreal and Vancouver, 2 each in Winnipeg, Edmonton and London, and 1 each in Halifax, Hamilton, Ottawa and Saskatoon)

The Canadian-based projects will be implemented worldwide (a majority of them implemented simultaneously in more than one country):

15 countries in Africa (5 in Kenya, 4 in Tanzania, 3 each in Uganda and Ethiopia, 2 each in Rwanda, Somalia, South Africa, South Sudan, and Zambia, and 1 each in Benin, Botswana, Ghana,  Malawi, Nigeria, and DR Congo)
8 countries in Asia (8 in India, 6 in Bangladesh, 1 each in Bhutan, China, Nepal, Pakistan, Philippines and Thailand)
5 countries in South and Latin America (Belize, Brazil, Colombia, Jamaica, Peru.) and
1 in the Middle East (Egypt)

Including today’s grants, total investments to date under the Grand Challenges Canada “Stars in Global Health” program is $32 million in 295 projects.

For full details: http://bit.ly/HOLt5b

* * * * *

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global

health. We are funded by the Government of Canada through the Development Innovation Fund announced in the 2008 Federal Budget. We fund innovators in low- and middle-income countries and Canada. Grand Challenges Canada works with the International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR), and other global health foundations and organizations to find sustainable, long-term solutions through Integrated Innovation − bold ideas that integrate science, technology, social and business innovation. Grand Challenges Canada is hosted at the Sandra Rotman Centre.

Please visit grandchallenges.ca  and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Canada’s International Development Research Centre

The International Development Research Centre (IDRC) supports research in developing countries to promote growth and development. IDRC also encourages sharing this knowledge with policymakers, other researchers and communities around the world. The result is innovative, lasting local solutions that aim to bring choice and change to those who need it most. As the Government of Canada’s lead on the Development Innovation Fund, IDRC draws on decades of experience managing publicly funded research projects to administer the Development Innovation Fund. IDRC also ensures that developing country researchers and concerns are front and centre in this exciting new initiative.

www.idrc.ca

About Canadian Institutes of Health Research

The Canadian Institutes of Health Research (CIHR) is the Government of Canada’s health research investment agency. CIHR’s mission is to create new scientific knowledge and to enable its translation into improved health, more effective health services and products, and a strengthened Canadian health care system. Composed of 13 Institutes, CIHR provides leadership and support to more than 14,100 health researchers and trainees across Canada. CIHR will be responsible for the administration of international peer review, according to international standards of excellence. The results of CIHR-led peer reviews will guide the awarding of grants by Grand Challenges Canada from the Development Innovation Fund.

www.cihr-irsc.gc.ca

About the Department of Foreign Affairs, Trade and Development Canada

The mandate of Foreign Affairs, Trade and Development Canada is to manage Canada’s diplomatic and consular relations, to encourage the country’s international trade, and to lead Canada’s international development and humanitarian assistance.

www.international.gc.ca

About Sandra Rotman Centre

The Sandra Rotman Centre is based at University Health Network and the University of Toronto. We develop innovative global health solutions and help bring them to scale where they are most urgently needed. The Sandra Rotman Centre hosts Grand Challenges Canada.

www.srcglobal.org

I have found it confusing that there’s a Grand Challenges Canada and the Bill and Melinda Gates Foundation has a Grand Challenges programme, both of which making funding announcements at this time of year. I did make some further investigations which I noted in my Dec. 22, 2011 posting,

Last week, the Bill & Melinda Gates Foundation announced a $21.1 M grant over three years for research into point-of-care diagnostic tools for developing nations. A Canadian nongovermental organization (NGO) will be supplementing this amount with $10.8 M for a total of $31.9 M. (source: Dec. 16, 2011 AFP news item [Agence France-Presse] on MedicalXpress.com)

At this point, things get a little confusing. The Bill & Melinda Gates Foundation has a specific program called Grand Challenges in Global Health and this grant is part of that program. Plus, the Canadian NGO is called Grand Challenges Canada (couldn’t they have found a more distinctive name?), which is funded by a federal Canadian government initiative known as the Development Innovation Fund (DIF). …

Weirdly, no one consulted with me when they named the Bil & Melinda Gates Foundation programme or the Canadian NGO.

Clay disks and flowerpots that purify water

Ben Schiller writes in a Mar. 1, 2013 article for Fast Company about a not-for-profit organization, PureMadi, a joint venture between the University of Virginia (US) and the University of Venda (South Africa) and its water purification technology,

PuriMadi has already built a factory in the Limpopo province of South Africa and hopes to expand further. “Eventually that factory will be capable of producing about 500 to 1,000 filters per month, and our 10-year plan is to build 10 to 12 factories in South Africa and other countries,” Smith says. “We plan to eventually serve at least 500,000 people per year with new filters.”

The University of Virginia Feb. 5, 2013 news release by Fariss Samarrai describes both a disc and a flowerpot version of the water purification technology (Note: Some links have been removed),

PureMadi, a nonprofit University of Virginia organization, will introduce a new invention – a simple ceramic water purification tablet – during its one-year celebration event Friday [Feb. 8, 2013] from 7 to 11 p.m. at Alumni Hall.

Called MadiDrop, the tablet – developed and extensively tested at U.Va. – is a small ceramic disk impregnated with silver or copper nanoparticles. It can repeatedly disinfect water for up to six months simply by resting in a vessel where water is poured. It is being developed for use in communities in South Africa that have little or no access to clean water.

“Madi” is the Tshivenda South African word for water. PureMadi brings together U.Va. professors and students to improve water quality, human health, local enterprise and quality of life in the developing world. The organization includes students and faculty members from engineering, architecture, medicine, nursing, business, commerce, economics, anthropology and foreign affairs.

During the past year, PureMadi has established a water filter factory in Limpopo province, South Africa, employing local workers. The factory produced several hundred flowerpot-like water filters, according to James Smith, a U.Va. civil and environmental engineer who co-leads the project with Dr. Rebecca Dillingham, director of U.Va.’s Center for Global Health.

Here’s the flowerpot filter,

 A worker molds a filter from local clay, sawdust and water. (Photo: Rachel Schmidt)


A worker molds a filter from local clay, sawdust and water. (Photo: Rachel Schmidt)

Here are the discs or, as they are known, the MadiDrops,

 The new MadiDrops can be produced in the same factories as the filters. (Photo: Rachel Schmidt)


The new MadiDrops can be produced in the same factories as the filters. (Photo: Rachel Schmidt)

The factory is more than just a producer of water purification technologies, from the University of Virgina news release,

“Eventually that factory will be capable of producing about 500 to 1,000 filters per month, and our 10-year plan is to build 10 to 12 factories in South Africa and other countries,” Smith said. “Each filter can serve a family of five or six for two to five years, so we plan to eventually serve at least 500,000 people per year with new filters.”

The idea is to create sustainable businesses that serve their communities and employ local workers. A small percentage of the profits go back to PureMadi and will be used to help establish more factories.

The PureMadi website’s About page offers more information about the partners, the technology, and the economic impact,

PureMadi has been created by an interdisciplinary collaboration of students and faculty at the University of Virginia.  In partnership with the University of Venda in Thohoyandou, South Africa, and developing-world communities in Limpopo Province, South Africa, PureMadi is working to provide sustainable solutions to global water problems.

Our first project is the development of a sustainable, ceramic water filter factory in South Africa.  Ceramic filters are a point-of-use (e.g. household-level) water treatment technology.  Ceramic filters can be produced with local materials (clay, sawdust, and water) and local labor. The materials are mixed in appropriate proportions, pressed into the shape of a filter pot, and fired in a kiln at 900 ˚C.  Upon firing, the clay forms a ceramic and the sawdust combusts, leaving a porous ceramic matrix for filtration.  In addition, the filters are treated with a dilute solution of silver nanoparticles.  The nanoparticles lodge in the pore space of the ceramic matrix and act as a highly effective disinfectant for waterborne pathogens like Vibrio cholerae and pathogenic strains of Escherichia coli.   Untreated water can then be passed through the filter and collected in a lower reservoir with a spigot to obtain purified water.

In the field and in the laboratory, we have demonstrated that this technology is highly effective at purifying water and the filters are socially acceptable to developing-world communities.  In some of our most recent work, we have shown that the filters significantly improve the health outcomes of human populations using the filters relative to groups who only drink untreated water.

A filter factory can become a sustainable business venture that provides economic stimulus to the local community.  Our goal is to create a blueprint for a successful factory, including its architecture, efficiency of water and energy use, technological performance of the filter itself, and an effective and sustainable business model.

While the flowerpot filter has been well received the MadiDrop fills another need, from the University of Virginia news release,

MadiDrop is an alternative to the flowerpot filter, but ideally would be used in conjunction with it. The plan is to mass-produce the product at the same factories where the PureMadi filters are produced.

“MadiDrop is cheaper, easier to use, and is easier to transport than the PureMadi filter, but because it is placed into the water, rather than having the water filter through it, the MadiDrop is not effective for removing sediment in water that causes discoloration or flavor impairment,” Smith said. “But its ease of use, cost-effectiveness and simple manufacturing process should allow us to make it readily available to a substantial population of users, more so than the more expensive PureMadi filter.”

Testing shows that the filters are safe to use and release only trace amounts of silver or copper particles, well within the safe water standards of the developed world. The filters also would be useful in rural areas of developed countries such as the United States where people rely on untreated well water.

Smith noted that U.Va. Architecture School professor Anselmo Canfora and his students have worked closely with PureMadi to design sustainable filter factories for developing countries that would optimize use of local labor and materials.

The National Science Foundation, the National Institutes of Health, U.Va.’s Jefferson Public Citizen Program and the Vice Provost for Global Affairs provide support to PureMadi. Partners include the University of Venda in South Africa; Potters for Peace, a nonprofit organization committed to providing safe drinking water in the developing world; and local communities in Limpopo province in South Africa.

Taken in conjunction with my Feb. 28, 2013 posting titled, Silver nanoparticles, water, the environment, and toxicity, where I juxtaposed two articles about toxicity and silver nanoparticles (they’re ok/they’re not ok) to illustrate the complexity surrounding the question of risk, this article which features silver (and copper) nanoparticles in use for water purification adds another dimension to the question. What are the risks?, to add, are they worth taking?

Tata Swach and its jaunty silver nanoparticle water purifier advertising campaign

The Nov. 19, 2012 news item on the Best Media Info Bureau website includes this advertisement which started airing on Indian television on Nov. 17, 2012,

Here’s a little more about the advertising campaign (from the news item),

Tata Swach Nanotech Water Purifier has launched a new ad campaign that emphasises on silver’s antibacterial qualities. The campaign showcases the advanced silver nanotechnology used by Tata Swach to enhance silver’s purification power without any use of harmful chemicals. The TV commercial has been created by DraftFCB+Ulka.

The TVC [television commercial?] began airing on major channels, including high impact properties, from November 17, 2012. The ad campaign will be carried across television, print, radio, online and social media platforms.

There is some mention of safety but it is focused on how silver nanoparticles make the water safer from bacteria and viruses and there’s no hint that there are concerns the nanoparticles themselves might present a problem.

Removing pollutants from water with nano-brushes

The Jan. 16, 2012 news item ( by Jim Hannah) on Nanowerk about nano-brushes and water pollution reminded of an MIT (Massachusetts Institute of Technology) event at the last Venice Biennale, which featured a demonstration of nanotechnology-enabled oil-absorbing robots (my Aug. 26 2010 posting includes a video of the MIT project, Seaswarm).

Here’s an overview of the situation, from the news item,

The need to efficiently purify water is mushrooming into a massive global issue as human and industrial consumption of water grows.

The United Nations estimates that about 1.1 billion people currently lack access to safe water. Several forecasts suggest that freshwater may become the “oil” of the 21st century – expensive, scarce and the cause of geo-political conflicts.

In the United States, aging water-treatment infrastructure is struggling to keep up with growing threats to the clean-water supply, making water purification a major energy expense. Technologies like the “nano-brush” may provide some relief.

Dr. Sharmila Mukhopadhyay of Wright State University (Ohio, US) is working on the problem with her research team and they are developing (from the news item),

… near molecular-sized “nano-brushes.”

These fuzzy structures have bristles made up of thousands of tiny, jellyfish-like strands. The increased surface area of the bristles, with proper coatings, allows them to behave like powerful cleaners that kill bacteria and destroy contaminants that pollute water.

Here’s a brief description of how this would work,

Different materials can be broken down into nano-particles and then attached to the bristles of the brushes.

For example, particles of silver kill bacteria on contact without being dispersed as pollutants in the water. Particles of palladium break up carbon-tetrachloride and other water pollutants. And particles of titanium oxide can zap pollutants when activated by sunlight.

Mukhopadhyay plans to attach three or four different kinds of water-purifying particles to the nano-brushes. “So simultaneously you can combine multiple environmental cleanup applications into one single component,” she said.

They have been testing this solution in the lab and they appear to be confident that it will be deployed in the field in the next few years. I’m thrilled that the nanoparticles being used for the cleanup don’t become pollutants themselves (at least, not so far).

How to become a futurist; organic technology; clean water with carbon nanotubes

I’ve always wondered how futurists look into the future (and how do they get their jobs?). At last I’ve found the answer to my first question in an article by Jamais Cascio in Fast Company.

In this entry in the occasional series, we’ll take a look at gathering useful data.Like the first step, Asking the Question, Scanning the World seems like it would be easier than it really is. In my opinion, it may actually be the hardest step of all, because you have to navigate two seemingly contradictory demands:

  • You need to expand the horizons of your exploration, because the factors shaping how the future of the dilemma in question will manifest go far beyond the narrow confines of that issue.
  • You need to focus your attention on the elements critical to the dilemma, and not get lost in the overwhelming amount of information out there.

You should recognize up front that the first few times you do this, you’ll miss quite a few of the key drivers; even experienced futurists end up missing a some important aspects of a dilemma. It’s the nature of the endeavor: We can’t predict the future, but we can try to spot important signifiers of changes that will affect the future. We won’t spot them all, but the more we catch, the more useful our forecasts.

The process of opening up and narrowing simultaneously sounds similar to how any kind of research is done, that is, if it’s going to be groundbreaking.

There’s an announcement from India about a new energy-efficient single treatment water purification process. From the news item on Nanowerk,

Minister of Rural Water Supply, Hon. Minister Viswarup and other leaders in Hyderabad, India today. Initial tests, performed at Indian Institute of Technology (IIT) Kanpur, confirmed that the majority of the drinking water available in India contains toxins that can be extremely hazardous to human health. The technology developed in collaboration with IIT Kanpur and North Carolina-based Cnanoz can remove harmful pathogens and toxic ingredients, such as Arsenic, Fluoride, Lead, Cadmium, DDT, hydrocarbon wastes and nitrates in an eco-friendly and economical way. Drinking water contaminated with toxic chemicals over an extended period of time can promote harmful gene mutations that can cause neurological disorders, mental and physical disabilities. The preventive aspect of the filtration system can have a significant positive impact to improve public health survival and reduce health care costs.

No word on health and safety or environmental issues or any details about the technology can be found in the announcement so I looked on the website for the company (Cnanoz) that developed the product. Nothing much there either but it is slick and easily navigable.

I’ve gotten more interested in the interplay between organic and  inorganic materials and this research is quite intriguing to me. From the news item on Nanowerk,

Single crystals of the mineral calcite — the chief material in limestone — are predictable, homogeneous and, well, a little boring. But scientists have long marveled at how biological crystals of calcite grow together with other organic materials to form, for example, shells and sea urchin spines. Biologists and materials scientists would love to know exactly how to re-create such natural composites in the lab.

“We knew the organics were in there, but what no one had been able to do up until now was actually see what that organic-inorganic interface looked like,” said [Lara] Estroff [assistant professor of materials science and engineering], whose lab focuses on the synthesis and characterization of bio-inspired materials.

That’s it for today.