Monthly Archives: November 2012

Historians of science get ready for ‘Knowledge at Work’

The theme for this year’s 24th International Congress of History of Science, Technology and Medicine is ‘Knowledge at Work’. According to Rebekah Higgitt’s Nov. 26, 2012 posting on the Guardian science blogs, the congress is on track to be the largest history of science conference ever held in the UK (Note: I have removed links),

This Friday [Nov. 30, 2012] sees the deadline for submissions to what will be the largest ever meeting of historians of science in the UK, and almost certainly the largest for at least a generation to come.

Last Friday already saw the closing date for organised symposiums within the International Congress of History of Science, Technology and Medicine, and the organisers tweeted:

@ichstm2013

 

#ichstm has just received its 1000th symposium paper abstract.

With the individual submissions still to come in, this promises to be huge for the history of science, which usually counts conference delegates in the 10s or 100s.

The 24th international congress will be held in Manchester, UK from Monday, July 22, 2013 – Sunday, July 28, 2013. Here’s more from the congress home page,

Welcome to the website for the 2013 International Congress, whose theme is Knowledge at Work.

The International Congress of History of Science, Technology and Medicine is the largest event in the field, and takes place every four years. Recent meetings have been held in Mexico City (2001), Beijing (2005) and Budapest (2009).

In 2013, the Congress will take place in Manchester, the chief city of Northwest England, and the original “shock city” of the Industrial Revolution. Congress facilities will be provided by The University of Manchester, with tours and displays on local scientific, technological and medical heritage co-ordinated by members of the University’s Centre for the History of Science, Technology and Medicine.

Here’s some information about individual submissions from the Call for stand-alone papers webpage,

The theme of the 24th Congress is ‘Knowledge at work’. We construe this theme broadly, and encourage studies of the creation, dissemination and deployment of knowledge and practice across all periods, and from a variety of methodological and historiographical approaches. Possible areas of investigation may include, but are not limited to

  • case studies of knowledge-making and knowledge-use in particular scientific, technological and medical communities
  • the use and adaptation of scientific knowledge in the workplace, the home, and the wider world
  • how facts, and other knowledge-claims, travel between disciplines, countries and communities
  • relationships between those knowledge-making enterprises which are described as ‘science’ and those which are not, and the dynamics of the boundaries between them
  • definitions and meanings of ‘pure’, ‘fundamental’ and ‘applied’ research
  • how scientists, engineers and healthcare professionals (and their historical antecedents) work, and whom they work for
  • the status relations of knowledge and work, including the roles of ‘artists’, ‘artisans’, ‘professionals’, ‘amateurs’, ‘devotees’, ‘operatives’, ‘philosophers’, ‘adepts’, ‘scientists’ and ‘workers’
  • sites and geographies of knowledge-production and knowledge-exchange: laboratory, field, factory, hospital, ocean…
  • communication about science: forms and genres, advocacy and dissent, authorship and audience in print, manuscript, broadcasting, digital media and performance

Stand-alone submissions will normally be assembled thematically into groups of 4 presentations per 90-minute session. You should prepare a presentation of around 15 to 17 minutes’ duration, to be followed by 5 minutes of audience questions. Please plan carefully: the very high volume of activity at the Congress means it will be necessary to run strictly to time.

Most papers at the Congress are presented by sole authors. You may, however, submit a co-authored paper to be co-presented by two or, if necessary, three authors. All registered co-presenters should take an active role in delivering the paper.

If your research involves collaboration with colleagues who will not be attending the Congress, please do not list them as co-presenters (see “Attendance requirement”). Instead, please develop a solo paper based on the collaboration, crediting your colleagues as appropriate in your talk.

Language

Papers may be presented in any of the following languages: English, French, Spanish, German, Italian, Chinese, Portuguese, Russian and Arabic.

For review and documentation purposes, we require titles and abstracts for all proposals to be submitted in either English or French. If you will be presenting in another language, please also supply an equivalent title and abstract in that language.

In addition to the standard tours and extras, Higgitt’s post mentions something you may consider to be an incentive to submit,

There will also be a “fringe” that will include films, music, theatre and performance, aimed at the public as well as delegates. Importantly, there will also be an entire pub, the Jabez Clegg, handed over for the conference, selling, I’ve been promised, unique and appropriately-named cask beers. (It helps that the Manchester department includes a postgrad with experience of organising beer festivals and a historian of brewing.)

Good luck with your submission!

Hydro-Québec, graphite, and lithium-ion batteries

While Dexter Johnson at Nanoclast blog writes about an investigation into why the storage capacity of lithium-ion (Li-ion) batteries degrades in his Nov. 26, 2012 posting (Newly Developed Live Nanoscale Imaging Technique Promises Improvement in Li-ion Batteries), Hydro-Québec and Grafoid Inc. have signed a development deal for the next generation of lithium iron phosphate materials to be combined with graphene for next generation rechargeable batteries. From the Nov. 27, 2012 news item on Nanowerk,

The 50-50 collaborative agreement sets out terms with the objective of creating patentable inventions by combining graphene, supplied by Grafoid, with Hydro-Québec’s patented lithium iron phosphate technologies.

Two key, specific commercial target markets – the rechargeable automobile battery sectors and batteries for mobile electronic devices used in smartphones, computing tablets and laptop computers – were identified in the agreement.

Hydro-Québec will study Grafoid’s graphene conductivity, electrochemical performance and its effects in electrode formulations, electrolyte and separator optimizations. Detailed characterizations of Grafoid’s supplied materials will be undertaken at IREQ’s cutting edge facilities using its advanced electron microscopy, spectrographic and other in-house technologies.

Hydro-Québec will also supply lithium iron phosphate materials and its electrochemistry know how which it acquired under license from famed American inventor Dr. John Goodenough.

The Nov. 26, 2012 news release from Focus Graphite, which originated the news item, provides additional detail about the various principles in the deal,

About Focus Graphite

Focus Graphite Inc. is an emerging mid-tier junior mining development company, a technology solutions supplier and a business innovator. Focus is the owner of the Lac Knife graphite deposit located in the Côte-Nord region of northeastern Québec. The Lac Knife project hosts a NI 43-101 compliant Measured and Indicated mineral resource of 4.972 Mt grading 15.7% carbon as crystalline graphite with an additional Inferred mineral resource of 3.000 Mt grading 15.6% crystalline graphite  Focus’ goal is to assume an industry leadership position by becoming a low-cost producer of technology-grade graphite. On October 29th, 2012 the Company released the results of a Preliminary Economic Analysis (“PEA”) of the Lac Knife project which demonstrates that the project has robust economics and excellent potential to become a profitable producer of graphite.  As a technology-oriented enterprise with a view to building long-term, sustainable shareholder value, Focus Graphite is also investing in the development of graphene applications and patents through Grafoid Inc.

About Grafoid Inc.

Grafoid, Inc. is a privately held Canadian corporation investing in graphene applications and economically scalable production processes for graphene and graphene derivatives from raw, unprocessed, graphite ore. Focus Graphite Inc., (TSX-V: FMS; OTCQX: FCSMF; FSE: FKC) holds a 40% interest in Grafoid Inc. [emphasis mine]

About IREQ

Hydro-Québec’s research institute, IREQ, is a global leader in the development of advanced materials for battery manufacturing and creates leading edge processes from its state of the art facilities. IREQ holds more than 100 patent rights and has issued over 40 licenses for battery materials to some of the world’s most successful battery manufacturers and materials suppliers. Its areas of expertise include energy storage and IREQ is a lead partner with private sector companies in Québec to build EV and HEV charging stations in support of its technology developments. Its material development contributions are helping to develop safe, high-performance lithium ion batteries that can be charged more quickly and a greater number of times. IREQ promotes open innovation and partners with private firms, universities, government agencies and research centers in Québec and abroad. Its partnerships allow IREQ to develop, industrialize and market technologies resulting from those innovation projects.

About Hydro-Québec

Hydro-Québec is Canada’s largest electricity producer among the world’s largest hydroelectric power producers and a public utility that generates, transmits and distributes electricity. Its sole shareholder is the Québec government. It primarily exploits renewable generating options, in particular hydropower, and supports the development of wind energy through purchases from independent power producers. Its research institute, IREQ, conducts R&D in energy efficiency, energy storage and other energy-related fields. Hydro-Québec invests more than $100 million per year in research.

Here’s one last bit I want to highlight from the Focus Graphite news release,

“Commercially, and ultimately, our technology development partnership with Hydro-Québec aims to produce high capacity, LFP-graphene batteries with ultra short charging times and longer recyclable lifetimes,” Mr. Economo said [Gary Economo, President and Chief Executive Officer of both Grafoid Inc. and Focus Graphite].

He said the parties chose to focus their collaboration on LFP-graphene batteries and materials because of their short-term-to-market potential.

In light of Dexter’s very informative posting about Li-ion batteries and the investigation into why the storage capatcity degrades, I find this Hydro-Québec/Grafoid Inc. development provides insight into the relationship between scientific research and business and insight into the risks as the various groups compete to bring products to market or to improve those products such that they come to dominate the market.

One last comment, graphite flakes are also mined in Ontario as per both my July 25, 2011 posting and my Feb. 6, 2012 posting about Northern Graphite Corporation and its Bissett Creek mine.

NBD Nano startup company and the Namib desert beetle

In 2001, Andrew Parker and Chris Lawrence published an article in Nature magazine about work which has inspired a US startup company in 2012 to develop a water bottle that fills itself up with water by drawing moisture from the air. Parker’s and Lawrence’s article was titled Water capture by a desert beetle. Here’s the abstract (over 10 years later the article is still behind a paywall),

Some beetles in the Namib Desert collect drinking water from fog-laden wind on their backs1. We show here that these large droplets form by virtue of the insect’s bumpy surface, which consists of alternating hydrophobic, wax-coated and hydrophilic, non-waxy regions. The design of this fog-collecting structure can be reproduced cheaply on a commercial scale and may find application in water-trapping tent and building coverings, for example, or in water condensers and engines.

Some five years later, there was a June 15, 2006 news item on phys.org about the development of a new material based on the Namib desert beetle,

When that fog rolls in, the Namib Desert beetle is ready with a moisture-collection system exquisitely adapted to its desert habitat. Inspired by this dime-sized beetle, MIT [Massachusetts Institute of Technology] researchers have produced a new material that can capture and control tiny amounts of water.

The material combines a superhydrophobic (water-repelling) surface with superhydrophilic (water-attracting) bumps that trap water droplets and control water flow. The work was published in the online version of Nano Letters on Tuesday, May 2 [2006] {behind a paywall}.

Potential applications for the new material include harvesting water, making a lab on a chip (for diagnostics and DNA screening) and creating microfluidic devices and cooling devices, according to lead researchers Robert Cohen, the St. Laurent Professor of Chemical Engineering, and Michael Rubner, the TDK Professor of Polymer Materials Science and Engineering.

The MIT June 14, 2006 news release by Anne Trafton, which originated the news item about the new material, indicates there was some military interest,

The U.S. military has also expressed interest in using the material as a self-decontaminating surface that could channel and collect harmful substances.

The researchers got their inspiration after reading a 2001 article in Nature describing the Namib Desert beetle’s moisture-collection strategy. Scientists had already learned to copy the water-repellent lotus leaf, and the desert beetle shell seemed like another good candidate for “bio-mimicry.”

When fog blows horizontally across the surface of the beetle’s back, tiny water droplets, 15 to 20 microns, or millionths of a meter, in diameter, start to accumulate on top of bumps on its back.

The bumps, which attract water, are surrounded by waxy water-repelling channels. “That allows small amounts of moisture in the air to start to collect on the tops of the hydrophilic bumps, and it grows into bigger and bigger droplets,” Rubner said. “When it gets large, it overcomes the pinning force that holds it and rolls down into the beetle’s mouth for a fresh drink of water.”

To create a material with the same abilities, the researchers manipulated two characteristics — roughness and nanoporosity (spongelike capability on a nanometer, or billionths of a meter, scale).

By repeatedly dipping glass or plastic substrates into solutions of charged polymer chains dissolved in water, the researchers can control the surface texture of the material. Each time the substrate is dipped into solution, another layer of charged polymer coats the surface, adding texture and making the material more porous. Silica nanoparticles are then added to create an even rougher texture that helps trap water droplets.

The material is then coated with a Teflon-like substance, making it superhydrophobic. Once that water-repellent layer is laid down, layers of charged polymers and nanoparticles can be added in certain areas, using a properly formulated water/alcohol solvent mixture, thereby creating a superhydrophilic pattern. The researchers can manipulate the technique to create any kind of pattern they want.

The research is funded by the Defense Advanced Research Projects Agency and the National Science Foundation.

I’m not sure what happened with the military interest or the group working out of MIT in 2006 but on Nov. 23, 2012, BBC News online featured an article about a US startup company, NBD Nano, which aims to bring a self-filling water bottle based on Namib desert beetle to market,

NBD Nano, which consists of four recent university graduates and was formed in May, looked at the Namib Desert beetle that lives in a region that gets about half an inch of rainfall per year.

Using a similar approach, the firm wants to cover the surface of a bottle with hydrophilic (water-attracting) and hydrophobic (water-repellent) materials.

The work is still in its early stages, but it is the latest example of researchers looking at nature to find inspiration for sustainable technology.

“It was important to apply [biomimicry] to our design and we have developed a proof of concept and [are] currently creating our first fully-functional prototype,” Miguel Galvez, a co-founder, told the BBC.

“We think our initial prototype will collect anywhere from half a litre of water to three litres per hour, depending on local environments.”

According to the Nov. 25, 2012 article by Nancy Owano for phys.org, the company is at the prototype stage now,

NBD Nano plans to enter the worldwide marketplace between 2014 and 2015.

You can find out more about NBD Nano here.

Crowdfunding Qii, a foldable, soft keyboard made of a carbon nanotube/fullerene hybrid

Canatu Ltd. is a Finnish company that’s trying to crowdfund its foldable, soft keyboard, Qii, on indiegogo. Here’s more about Canatu’s keyboard project from the Nov. 24, 2012 news item on Nanowerk,

Canatu Ltd., a developer of a new class of versatile carbon nanomaterial based custom films and sensors for flexible and formable touch devices, is launching Qii – the world’s first, truly mobile, rollable touch accessory.

The company appears to be creating a new class of product under the Qii brand name. From the indiegogo campaign description,

With Qii, your smartphone and your imagination, any surface can be effectively turned into a touch surface and any “dumb” object can be turned into a “smart” object. Nanotechnology and organic electronics make it possible. The idea is simple, but the applications are endless.

As our first Qii product, we’re offering a full QWERTY computer keyboard, including a number pad and function keys, wirelessly connected to your smartphone. Because its ultra thin and flexible, Qii is both full sized and pocket sized, so you’ll be able to effortlessly type and surf anywhere you go, be it in a café, the woods, or a car, train, bus or plane. It has an anti fingerprint coating to keep it clean and a textured surface for easy touch typing. It’s dirt and water resistant, so you don’t have to worry about spilling and it’s easily washable with soap and water. And, since Qii’s rollable electronics are printed, it’s tough.

Qii’s case is also a touchpad, allowing you to point, tap and scroll for easy surfing and graphical editing. You can use Qii on most any surface, so you can check your email on your friend’s belly, update your Facebook on your pet, or write your next novel on your pillow.

Some keyboards claim to be rollable, but you can’t roll them up and fit them in your pocket. We use a new kind of flexible transparent electronic film together with a new kind of touch sensing technology that can sense both position and force to create a compact and portable and programmable touch surface.

Qii will work with iPhone, iPod, iPad, Android, iPhone, Blackberry, Windows Phone, and Palm phones according to each platform’s available QWERTY keyboard and pointer standards.

Intriguing, non? You might want to watch this video for a demonstration,

There is a very brief description of the technology in the campaign material,

Our team has been working for years with our partners to bring Qii to life. Together we have developed new carbon based nanomaterials, new dry printing manufacturing techniques and now new, ultra-high transparency, flexible, bendable, stretchable, rollable and foldable touch technologies and unique touch algorithms to make Qii possible. It starts with our flexible, transparent, electrically conductive film made with a new carbon nanomaterial connected to state-of-the art sensing electronics to make a flexible, transparent touch sensing surface that determines both your finger’s position and force.

We’ll introduce the Qii in pliable hard coated plastic, but, in the future, the sensor can be printed on most anything, even paper, rubber or fabric.

I took a look at the Canatu website and found this information about a material they’ve developed and named, NanoBuds® and which I believe forms the basis for the company’s proposed Qii keyboard,

Canatu has developed a new material, the Carbon NanoBud®, which is a hybrid of Carbon Nanotubes and fullerenes. The hybridization is achieved directly in the material synthesis process and the resulting material combines the best features of both fullerenes and nanotubes.

Canatu’s first products focus on taking advantage of the high conductivity, high aspect ratio, low work function, chemical stability and mechanical flexibility of NanoBuds® to make the world’s highest performance carbon based transparent conductive film for transparent conductors in touch, haptics, displays and photovoltaics. These films, consisting of randomly oriented deposits of NanoBuds on polymer or glass substrates, are flexible, bendable, stretchable and have excellent transparency conductivity performance as shown below. [emphasis mine]

David Brown, the company’s Chief Technical Officer (CTO) originally announced the crowdfunding Qii campaign would take place on Kickstarter in Dan Rogers’s Oct. 10, 2012 article for Plastic Electronics,

An accessory using a novel nanomaterial touchscreen will be launched via the Kickstarter project in the coming weeks, according to nanotechnology developer Canatu.

Based in Finland, Canatu supplies carbon NanoBuds that can be used as a conductive layer alternative to indium tin oxide, which is considered too brittle for flexible electronics.

I’m not sure what happened with the ‘Kickstarter’ plans but the indiegogo campaign has 41 days left as Canatu tries to raise $1,850,000 by Jan. 6, 2013. The company must raise the entire amount requested or it receives nothing.

Good luck to the folks at Canatu. Qii looks like a product which would make moving around much easier. Imagine not having to lug your laptop or tablet around while enjoying the benefits of a full size keyboard.

Existential risk

The idea that robots of one kind or another (e.g. nanobots eating up the world and leaving grey goo, Cylons in both versions of Battlestar Galactica trying to exterminate humans, etc.) will take over the world and find humans unnecessary  isn’t especially new in works of fiction. It’s not always mentioned directly but the underlying anxiety often has to do with intelligence and concerns over an ‘explosion of intelligence’. The question it raises,’ what if our machines/creations become more intelligent than humans?’ has been described as existential risk. According to a Nov. 25, 2012 article by Sylvia Hui for Huffington Post, a group of eminent philosophers and scientists at the University of Cambridge are proposing to found a Centre for the Study of Existential Risk,

Could computers become cleverer than humans and take over the world? Or is that just the stuff of science fiction?

Philosophers and scientists at Britain’s Cambridge University think the question deserves serious study. A proposed Center for the Study of Existential Risk will bring together experts to consider the ways in which super intelligent technology, including artificial intelligence, could “threaten our own existence,” the institution said Sunday.

“In the case of artificial intelligence, it seems a reasonable prediction that some time in this or the next century intelligence will escape from the constraints of biology,” Cambridge philosophy professor Huw Price said.

When that happens, “we’re no longer the smartest things around,” he said, and will risk being at the mercy of “machines that are not malicious, but machines whose interests don’t include us.”

Price along with Martin Rees, Emeritus Professor of Cosmology and Astrophysics, and Jaan Tallinn, Co-Founder of Skype, are the driving forces behind this proposed new centre at Cambridge University. From the Cambridge Project for Existential Risk webpage,

Many scientists are concerned that developments in human technology may soon pose new, extinction-level risks to our species as a whole. Such dangers have been suggested from progress in AI, from developments in biotechnology and artificial life, from nanotechnology, and from possible extreme effects of anthropogenic climate change. The seriousness of these risks is difficult to assess, but that in itself seems a cause for concern, given how much is at stake. …

The Cambridge Project for Existential Risk — a joint initiative between a philosopher, a scientist, and a software entrepreneur — begins with the conviction that these issues require a great deal more scientific investigation than they presently receive. Our aim is to establish within the University of Cambridge a multidisciplinary research centre dedicated to the study and mitigation of risks of this kind.

Price and Tallinn co-wrote an Aug. 6, 2012 article for the Australia-based, The Conversation website, about their concerns,

We know how to deal with suspicious packages – as carefully as possible! These days, we let robots take the risk. But what if the robots are the risk? Some commentators argue we should be treating AI (artificial intelligence) as a suspicious package, because it might eventually blow up in our faces. Should we be worried?

Asked whether there will ever be computers as smart as people, the US mathematician and sci-fi author Vernor Vinge replied: “Yes, but only briefly”.

He meant that once computers get to this level, there’s nothing to prevent them getting a lot further very rapidly. Vinge christened this sudden explosion of intelligence the “technological singularity”, and thought that it was unlikely to be good news, from a human point of view.

Was Vinge right, and if so what should we do about it? Unlike typical suspicious parcels, after all, what the future of AI holds is up to us, at least to some extent. Are there things we can do now to make sure it’s not a bomb (or a good bomb rather than a bad bomb, perhaps)?

It appears Price, Rees, and Tallinn are not the only concerned parties, from the Nov. 25, 2012 research news piece on the Cambridge University website,

With luminaries in science, policy, law, risk and computing from across the University and beyond signing up to become advisors, the project is, even in its earliest days, gathering momentum. “The basic philosophy is that we should be taking seriously the fact that we are getting to the point where our technologies have the potential to threaten our own existence – in a way that they simply haven’t up to now, in human history,” says Price. “We should be investing a little of our intellectual resources in shifting some probability from bad outcomes to good ones.”

Price acknowledges that some of these ideas can seem far-fetched, the stuff of science fiction, but insists that that’s part of the point.

According to the Huffington Post article by Lui, they expect to launch the centre next year (2013). In the meantime, for anyone who’s looking for more information about the ‘intelligence explosion’ or  ‘singularity’ as it’s also known, there’s a Wikipedia essay on the topic.  Also, you may want to stay tuned to this channel (blog) as I expect to have some news about an artificial intelligence project based at the University of Waterloo (Ontario, Canada) and headed by Chris Eliasmith at the university’s Centre for Theoretical Neuroscience, later this week.

Free the nano—stop patenting publicly funded research

Joshua Pearce, a professor at Michigan Technological University, has written a commentary on patents and nanotechnology for Nature magazine which claims the current patent regimes strangle rather than encourage innovation. From the free article,  Physics: Make nanotechnology research open-source by Joshua Pearce in Nature 491, 519–521 (22 November 2012) doi:10.1038/491519a (Note: I have removed footnotes),

Any innovator wishing to work on or sell products based on single-walled carbon nanotubes in the United States must wade through more than 1,600 US patents that mention them. He or she must obtain a fistful of licences just to use this tubular form of naturally occurring graphite rolled from a one-atom-thick sheet. This is because many patents lay broad claims: one nanotube example covers “a composition of matter comprising at least about 99% by weight of single-wall carbon molecules”. Tens of others make overlapping claims.

Patent thickets occur in other high-tech fields, but the consequences for nanotechnology are dire because of the potential power and immaturity of the field. Advances are being stifled at birth because downstream innovation almost always infringes some early broad patents. By contrast, computing, lasers and software grew up without overzealous patenting at the outset.

Nanotechnology is big business. According to a 2011 report by technology consultants Cientifica, governments around the world have invested more than US$65 billion in nanotechnology in the past 11 years [my July 15, 2011 posting features an interview with Tim Harper, Cientfica CEO and founder, about the then newly released report]. The sector contributed more than $250 billion to the global economy in 2009 and is expected to reach $2.4 trillion a year by 2015, according to business analysts Lux Research. Since 2001, the United States has invested $18 billion in the National Nanotechnology Initiative; the 2013 US federal budget will add $1.8 billion more.

This investment is spurring intense patent filing by industry and academia. The number of nanotechnology patent applications to the US Patent and Trademark Office (USPTO) is rising each year and is projected to exceed 4,000 in 2012. Anyone who discovers a new and useful process, machine, manufacture or composition of matter, or any new and useful improvement thereof, may obtain a patent that prevents others from using that development unless they have the patent owner’s permission.

Pearce makes some convincing points (Note: I have removed a footnote),

Examples of patents that cover basic components include one owned by the multinational chip manufacturer Intel, which covers a method for making almost any nanostructure with a diameter less than 50 nm; another, held by nanotechnology company NanoSys of Palo Alto, California, covers composites consisting of a matrix and any form of nanostructure. And Rice University in Houston, Texas, has a patent covering “composition of matter comprising at least about 99% by weight of fullerene nanotubes”.

The vast majority of publicly announced IP licence agreements are now exclusive, meaning that only a single person or entity may use the technology or any other technology dependent on it. This cripples competition and technological development, because all other would-be innovators are shut out of the market. Exclusive licence agreements for building-block patents can restrict entire swathes of future innovation.

Pearce’s argument for open source,

This IP rush assumes that a financial incentive is necessary to innovate, and that without the market exclusivity (monopoly) offered by a patent, development of commercially viable products will be hampered. But there is another way, as decades of innovation for free and open-source software show. Large Internet-based companies such as Google and Facebook use this type of software. Others, such as Red Hat, make more than $1 billion a year from selling services for products that they give away for free, like Red Hat’s version of the computer operating system Linux.

An open-source model would leave nanotechnology companies free to use the best tools, materials and devices available. Costs would be cut because most licence fees would no longer be necessary. Without the shelter of an IP monopoly, innovation would be a necessity for a company to survive. Openness reduces the barrier for small, nimble entities entering the market.

John Timmer in his Nov. 23, 2012 article for Wired.co.uk expresses both support and criticism,

Some of Pearce’s solutions are perfectly reasonable. He argues that the National Science Foundation adopt the NIH model of making all research it funds open access after a one-year time limit. But he also calls for an end of patents derived from any publicly funded research: “Congress should alter the Bayh-Dole Act to exclude private IP lockdown of publicly funded innovations.” There are certainly some indications that Bayh-Dole hasn’t fostered as much innovation as it might (Pearce notes that his own institution brings in 100 times more money as grants than it does from licensing patents derived from past grants), but what he’s calling for is not so much a reform of Bayh-Dole as its elimination.

Pearce wants changes in patenting to extend well beyond the academic world, too. He argues that the USPTO should put a moratorium on patents for “nanotechnology-related fundamental science, materials, and concepts.” As we described above, the difference between a process innovation and the fundamental properties resulting in nanomaterial is a very difficult thing to define. The USPTO has struggled to manage far simpler distinctions; it’s unrealistic to expect it to manage a moratorium effectively.

While Pearce points to the 3-D printing sector admiringly, there are some issues even there, as per Mike Masnick’s Nov.  21, 2012 posting on Techdirt.com (Note:  I have removed links),

We’ve been pointing out for a while that one of the reasons why advancements in 3D printing have been relatively slow is because of patents holding back the market. However, a bunch of key patents have started expiring, leading to new opportunities. One, in particular, that has received a fair bit of attention was the Formlabs 3D printer, which raised nearly $3 million on Kickstarter earlier this year. It got a ton of well-deserved attention for being one of the first “low end” (sub ~$3,000) 3D printers with very impressive quality levels.

Part of the reason the company said it could offer such a high quality printer at a such a low price, relative to competitors, was because some of the key patents had expired, allowing it to build key components without having to pay astronomical licensing fees. A company called 3D Systems, however, claims that Formlabs missed one patent. It holds US Patent 5,597,520 on a “Simultaneous multiple layer curing in stereolithography.” While I find it ridiculous that 3D Systems is going legal, rather than competing in the marketplace, it’s entirely possible that the patent is valid. It just highlights how the system holds back competition that drives important innovation, though.

3D Systems claims that Formlabs “took deliberate acts to avoid learning” about 3D Systems’ live patents. The lawsuit claims that Formlabs looked only for expired patents — which seems like a very odd claim. Why would they only seek expired patents? …

I strongly suggest reading both Pearce’s and Timmer’s articles as they both provide some very interesting perspectives about nanotechnology IP (intellectual property) open access issues. I also recommend Mike Masnick’s piece for exposure to a rather odd but unfortunately not uncommon legal suit designed to limit competition in a relatively new technology (3-D printers).

Baba Brinkman and the science of dating (Ingenious Nature show previews in New York)

I have mentioned Baba Brinkman before in the context of his Rap Guide to Evolution which is performed live and is available on CD. Tonight (Friday, Nov. 23, 2012), he previews a new show in New York, Ingenious Nature (from Baba’s Nov. 20, 2012 posting on his website),

INGENIOUS NATURE is a new off-Broadway show set to premiere on Friday at the Soho Playhouse. In the show I go on a series of dates with women I meet through OK Cupid (a dating website), while using evolutionary psychology as a roadmap to help understand the conflicts of interest and personality-clashes that ensue. Will I find a match worthy of parental investment? I date a creationist and explore the “behavioural immune system” theory of social conservatism, and a new-age yoga instructor teaches me about the seven chakras, which turn out to have a loose correlate in the psych lit as well. Putting theory into practice is wild ride when it comes to the science of mating.

Jamie Simmonds produced all the music for the show, and is also featured prominently in it as a character, performing virtuoso live turntablism to provide a distinctive sound and mood for each scene, as well as driving the storytelling ahead with comments and scratch quotes. Add a design team that includes Jason Boyd on lights (Q: “Can you make the theatre look like a Mobb Deep concert?” A: “Sure, I lit Mobb Deep’s last concert, so that shouldn’t be too hard”) and Erik Pearson (Canterbury Tales Remixed) on video projections, and you end up with something pretty spectacular.

There is a special deal (from Brinkman’s posting),

Darren Lee Cole, the artistic director of the Soho Playhouse, is directing the production with aplomb, and keeping me in check. Here’s an e-blast Darren just sent out, which includes a couple of awesome (limited time only) discount ticket deals for the show. If you will be in NYC between now and January 6th

Here you go

Single tickets normally $45 for $25 using code SOHO!

Or

Subscribe to the Soho Playhouse season: 3 tickets for $99

Break a leg, Baba!

Nanocanaries don’t die

It’s upsetting to think about the canaries in the mines singing to their heart’s content only to topple over and die when toxic gases make their presence felt during the mining process. The alternative, of course, is to sacrifice miners. Thankfully, choosing the lesser of two evils will no longer be necessary (actually, I don’t they’ve used canaries in quite a while) as scientists work on sensors that can detect any number of things not just toxic gases in the mines. The University of Massachusetts at Lowell is the latest to announce work on sensors (from the Nov. 15, 2012 news item on Nanowerk),

To detect the toxicity of engineered nanomaterials, such as carbon nanotubes, on living cells, electrical engineering Assoc. Prof. Joel Therrien — along with biology Prof. Susan Braunhut, chemistry Prof. Kenneth Marx and work environment Asst. Prof. Dhimiter Bello — has developed a “nanocanary,” the modern-day, high-tech equivalent of the canary in a coal mine that warned miners of dangerous buildups of toxic gases in the mine shaft.
The nanocanary is an ultrasensitive biosensor designed to continuously monitor tiny physiological changes in the live cells contained within it.

The Nov. 14, 2012 news release by Edwin L. Aguirre, which originated the news item, mentions a recent podcast by one of the researchers (Joel Therrien),

In a recent podcast produced by the Museum of Science in Boston, Therrien talked about the importance of studying how nano-sized particles affect human health and the environment as well as in the safe development of commercial nano products.

“Our biosensor has a wide range of applications, from testing for toxicity in nanomanufacturing to drug development and customized cancer therapeutics,” notes Therrien.

“In testing the toxicity of carbon nanotubes, for example, since the sensor can directly detect adverse effects on living cells, we are able to identify the threshold concentration at which carbon nanotubes lead to the cells’ death,” he explains. “The sensor can also be used to test the response of normal and cancerous cells to drug therapies. In the future, this technology may help guide oncologists in selecting the most appropriate drug for a cancer patient. We also see the potential for this to partially replace animals in testing drugs and other products.”

Therrien’s 16 min. podcast can be heard here.

Grand Challenges Canada announces latest Canadian and international ‘stars’ in global health grants

I last mentioned the Grand Challenges Canada organization in last year’s Dec. 22, 2011 posting. It’s a non-governmental organization funded by the Canadian federal government. I did express some confusion regarding the governmental/non-governmental aspects in last year’s posting,

So if I understand this rightly, the Canadian federal government created a new fund and then created a new NGO to administer that fund. I wonder how much money is required administratively for this NGO which exists solely to distribute DIF [Development Innovation Fund]. I’m glad to see that someone is getting some money for research out of this but it does seem labyrinthine at best.

Leaving that discussion aside, let’s focus on this year’s grantees and their projects (from the Nov. 22, 2012 news release about the Canadian grantees),

CANADA’S STARS IN GLOBAL HEALTH SHINE

FROM SEA TO SEA & WIN FUNDING FROM

GRAND CHALLENGES CANADA

From cities all across the country, 17 Canadians are selected for their bold out-of-the-box ideas to tackle debilitating disease and save lives in the Developing World

 Toronto.  Grand Challenges Canada, which is funded by the Government of Canada, announced today seed grants awarded to 17 innovators for their bold and creative ideas to tackle health conditions in poor countries. The Stars in Global Health program seeks unique, breakthrough and affordable ideas which can be transformative in addressing disease – innovations that can benefit the developed world as well. The 17 were selected from a total of 60 proposals submitted for the Canadian Stars program. A total of more than $1.7 million in funding will go to innovators from across Canada.

The bold ideas are breakthrough innovations such as mimicking rocket propelled technology, but in the body, to address maternal bleeding. A meter to detect HIV infection in fewer than 5 minutes. And a virtual reality game to assist stroke victims.

“Canada has a deep pool of talent dedicated to pursuing bold ideas that can have big impact in the developing world,” said Dr. Peter A. Singer, CEO of Grand Challenges Canada. “Grand Challenges Canada is proud to support these extraordinary innovators from across the country because they will make a difference to so many lives.”

“Canada works with our like-minded partners throughout the world to leverage our investments in health innovation so they’re focused on getting results,” said Foreign Affairs Minister John Baird. “We support Grand Challenges Canada’s Stars in Global Health so these innovators can apply their talents and further efforts to make the world a healthier and safer place.”

Each of the 17 innovators will receive a grant of $100,000 to develop their bold ideas, which include:

  • Vancouver: Dr. Christian Kastrup will mimic rocket technology to propel coagulant nanoparticles into the bloodstream and stop maternal bleeding, a major cause of death in the developing world. (for video: http://bit.ly/RWdW9w)
  • Vancouver: Dr. Robin Evans is developing a Burn Survival Kit, a high-tech solution to treat burn victims. The innovation is being tested in Uganda where often burns are untreated or mistreated. This unique kit will include a low-cost silver nanotubule dressing so that the treatment is affordable. (for video: http://bit.ly/T2rPFK)
  • Edmonton: Dr. Julianne Gibbs-Davis is creating a unique approach to diagnosing TB. It involves extracting DNA from the infected persons TB bacteria and does not require the usual temperature recycling that is expensive and difficult to implement in low resource settings. (for video: http://bit.ly/SKNLSf)
  • Hamilton: Dr. Leyla Soleymani is also tackling TB diagnosis with a hand-held, solar rechargeable, inexpensive diagnostic for rapid assessment of patients at the bedside.

(for video: http://bit.ly/T02HhS)

  • Toronto: Dr. Cheng Lu has a unique idea for tackling clinic and hospital infections. A coating can be sprayed or wiped on surfaces; once applied, the long-lasting anti-bacterial components are activated by sunlight or artificial light. Easy to use and effective.           (for video: http://bit.ly/TDxU6L)
  • Kingston: Dr. Karen Yeates will employ cell phones to improve cervical cancer screening and detection. It is being tested in remote areas of Tanzania.

(for video: http://bit.ly/RSvWTK)

  • Ottawa: Dr. Marion Roche will use social marketing to rejuvenate interest in taking zinc to control childhood diarrhea. (for video: http://bit.ly/QF7S8t)
  • Montreal: Dr. Philippe Archambault will use virtual reality to assist rehabilitation of stroke victims suffering from hand or arm immobilization. (for video: http://bit.ly/T2rX7X)
  • Montreal: Dr. Hanna Kienzler’s project is called “Defeating the Giant with a Slingshot” and is a novel approach to treating trauma in the developing world. The innovation results in blocking trauma memory and will be tested with torture victims in Nepal.

(for video: http://bit.ly/QF7TJx)

  • Montreal: Dr. Alexis Vallée-Bélisle is developing a meter to detect HIV infection in fewer than 5 minutes. This diagnostic will lead to earlier treatment of the disease.

(for video: http://bit.ly/XD4oFw)

  • Halifax: Dr. Patricia Livingston’s project will improve emergency services with a specific focus on crisis management for mothers delivering babies. The project is being tested in Rwanda. (for video: http://bit.ly/TCTACv)

“It is inspiring to see the wealth of Canadian talent working to improve the health of people in developing countries,” said Joseph L. Rotman, Chair of Grand Challenges Canada. “Our Stars in Global Health program is an excellent opportunity for these dedicated Canadian innovators, with support from the Government of Canada, to bring their bold ideas forward and improve global health conditions.”

In addition to these 17 Canadian innovators, Grand Challenges Canada announced today 51 grants totalling just over $7 million for Canadians and developing world innovators. Like the Canadian Stars, these innovators’ bold ideas aim to tackle global health challenges* (http://www.grandchallenges.ca/wp-content/uploads/stars-LMIC-newsrelease-2012nov22-en.pdf)

In total, 68 Canadian and developing world innovators were selected from 310 submitted proposals.

Upon completion of this grant, if their ideas are effective and proven, the innovators will be eligible for an additional Grand Challenges Canada scale-up funding of up to $1 million.

Grand Challenges Canada is funded by the Government of Canada through the Development

Innovation Fund announced in the 2008 Federal Budget.

For information on the grants and to see each Canadian Star’s short video explaining the project, visit http://www.grandchallenges.ca/stars-r3-grantee-announcement-en/.

Please visit grandchallenges.ca and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting bold ideas with big impact in global health. We are funded by the Government of Canada through the Development Innovation Fund announced in the 2008 Federal Budget. We fund innovators in low and middle income countries and Canada. Grand Challenges Canada works with the International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and other global health foundations and organizations to find sustainable long-term solutions through integrated innovation – bold ideas which integrate science, technology, social and business innovation. Grand Challenges Canada is hosted at the Sandra Rotman Centre.

www.grandchallenges.ca

 

About Canada’s International Development Research Centre

The International Development Research Centre (IDRC) supports research in developing countries to promote growth and development. IDRC also encourages sharing this knowledge with policymakers, other researchers and communities around the world. The result is innovative, lasting local solutions that aim to bring choice and change to those who need it most.

As the Government of Canada’s lead on the Development Innovation Fund, IDRC draws on decades of experience managing publicly funded research projects to administer the Development Innovation Fund. IDRC also ensures that developing country researchers and concerns are front and centre in this exciting new initiative.

www.idrc.ca

There’s also a Nov. 22, 2012 news release about the newly funded projects which are being led internationally. Here’s a few I find particularly interestin,

A new trading system in Kenya: seeds and fertilizers for proof of child vaccinations

(for video: http://bit.ly/UFlMmN)

To eliminate persistent pocket areas of Kenya where children are not vaccinated or undervaccinated, researchers will create a barcoded vaccination card redeemable for farm seeds and fertilizer.

Updated each time a child gets a vaccine, the card is taken to one of about 20,000 local agro-vet outlets, where the barcode is scanned using an app on a camera-equipped smartphone. The farmer would then redeem an “agri-credit” for essential farm inputs.

Lead researcher Benson Wamalwa of the University of Nairobi says the program “would powerfully incentivize parents to seek and adhere to their children’s immunization schedule even when hard pressed financially to reach a distant vaccination centre.

The idea is a practical solution that would significantly boost small farm productivity and incomes for poor household while safeguarding the general health of children in farming villages through up-to-date immunizations.”

Creating wealth from human waste in cholera-troubled Haiti

(for video: http://bit.ly/RBbN38)

The recent cholera outbreak in Haiti heightened both awareness of the problem’s cause and demand for better sanitation services — a tough challenge in environments without reliable running water. Meanwhile, national demand for farm and forest compost is high.

Hoping to capitalize on those twin realities, a Haitian group will build in urban slums the first new $200, waterless “EcoSan” toilets that produce revenue-generating compost, with hopes of inspiring entrepreneurs to replicate the project throughout Haiti and around the world, where 2.5 billion people lack sanitation access.

The project will document the number of toilets built and people receiving sanitation services, quantity of compost produced, sales and the outcomes of tests for pathogens and nutrients.

A $100 kitchen reno to reduce indoor pollution and problem pregnancies in Bangladesh

(for video: http://bit.ly/THAPNQ)

The International Energy Agency estimates that biomass fuels such as wood and dung will continue providing 30% of global energy in resource-poor settings though 2050.

Exposure to smoke from biomass cooking fuels, however, is known to cause placental dysfunction and is highly associated with low birth-weight babies in developing countries. Part of the solution could be a locally-made, simple prefabricated “$100 kitchen” featuring a clean-combustion stove.

Researchers in Bangladesh will conduct a randomized controlled trial with 430 willing mothers, 2 to 3 months pregnant, half of whom will use the innovative, well-ventilated $100 kitchen with reinforced cement infrastructure, a waste disposal system, and a stove that combusts biofuels with minimal smoke.

Mobile app to reduce obesity in northern Nigeria

(for video: http://bit.ly/THB7nV)

WHO projects that globally by 2015 about 2.3 billion adults will be overweight; more than 700 million will be obese — an epidemic growing fastest in developing countries and leading to diseases like type 2 diabetes, cancers, cardiovascular disease, hypertension and stroke.

In rural northern Nigeria, where mobile phone use is now common (use in Nigeria rose almost 1,300% in 2010-11), health researchers led by Sally Akarolo-Anthony will work with a high-tech firm to create a smartphone app to provide a virtual mentor and online buddy system.

The app will compute a user’s metabolic rate and caloric requirement, prompt daily exercise, collect data on activity and eating, offer healthy diet tips (e.g. white vs. brown rice), estimate the daily calorie intake required to meet a weight-loss goal, and monitor change over time.

I wish all of the researchers success with their projects, which would mean success for Grand Challenges Canada and this particular model for funding.