At this point it’s starting to seem like there are thousands and thousands of nanotoxicology studies so the announcement of a new study based in Québec (Canada) didn’t immediately cause excitement until I caught sight of the word ‘inflammation” which casts a newish light on the topic. From the Dec. 4, 2013 news item on Azonano,
… Professor Girard [Professor Denis Girard INRS–Institut Armand-Frappier Research Centre] will focus on the effects of NPs [nanoparticles] on human immune system cells (eosinophils) that play a key role in inflammation.
“Several studies on NPs have examined how tissues react in contact with these tiny foreign bodies,” said Girard. “Researchers have found that eosinophils flock to the contact site, but they have not examined the phenomenon in greater detail.” To further investigate why eosinophils come into contact with NPs and the role they play, protocols require expertise in both nanotoxicology and immunology, which is rare.
The Nov. 28, 2013 INRS [Institut national de la recherche scientifique] Université news release by Stéphanie Thibault, which originated the news item, delves into the issue of inflammatory responses,
According to Professor Girard, understanding the inflammatory response is currently a priority in the field of nanotoxicology. For a number of years, researchers have been observing links between exposure to NPs and asthmatic symptoms in some animals. Does the human body undergo similar inflammation upon contact with NPs? In the absence of any standards for workers, it’s best to take a closer look, insists Girard. “At this time, nanoparticles have not been properly identified and are often handled without protection. If they enter the body through the skin, respiratory tract, or even ingestion, we have no idea what happens next.” In his lab, a variety of approaches will help further understanding of how nanoparticles of different types and sizes interact. Cellular processes will be examined in detail.
At the rate at which NPs are being developed, Girard could be conducting systematic nanotoxicology studies for many years to come. “I will of course need the support of a strong team,” said Girard. “I already have one I am very proud of, and it will be expanded for the new project.” …
I gather there are going to be some jobs generated from this grant,
His research is being funded by Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST), which will award him a renewable $300,000 grant for the next three years.
… The IRSST grant will be used to hire staff and student researchers.
INRS (Institut national de la recherche scientifique) is one of Canada’s top universities in terms of research intensity (funding per faculty member). It brings together 150 professors, over 700 graduate and postgraduate students, and a hundred postdoctoral researchers at four centers in Montreal, Québec City, Laval, and Varennes. Conducting applied and fundamental research essential to the advancement of science in Quebec and around the world, our research teams plays a critical role in finding solutions to problems facing our society. Founded in 1969, INRS is one of the nine establishments that make up the Université du Québec network.
“The Institute is dedicated to fundamental and applied research, graduate studies, and the training of researchers. In keeping with its mission and objectives as a research university, the Institute specifically gears its activities towards Quebec’s economic, social, and cultural development, as well as the transfer of knowledge and technology stemming from all its fields of study.” INRS letters patent, 1999
There you have it.