Tag Archives: bed of nails

Killing bacteria on contact with dragonfly-inspired nanocoating

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Scientists in Singapore were inspired by dragonflies and cicadas according to a March 28, 2018 news item on Nanowerk (Note: A link has been removed),

Studies have shown that the wings of dragonflies and cicadas prevent bacterial growth due to their natural structure. The surfaces of their wings are covered in nanopillars making them look like a bed of nails. When bacteria come into contact with these surfaces, their cell membranes get ripped apart immediately and they are killed. This inspired researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR to invent an anti-bacterial nano coating for disinfecting frequently touched surfaces such as door handles, tables and lift buttons.

This technology will prove particularly useful in creating bacteria-free surfaces in places like hospitals and clinics, where sterilization is important to help control the spread of infections. Their new research was recently published in the journal Small (“ZnO Nanopillar Coated Surfaces with Substrate-Dependent Superbactericidal Property”)

Image 1: Zinc oxide nanopillars that looked like a bed of nails can kill a broad range of germs when used as a coating on frequently-touched surfaces. Courtesy: A*STAR

A March 28, 2018 Agency for Science Technology and Research (A*STAR) press release, which originated the news item, describes the work further,

80% of common infections are spread by hands, according to the B.C. [province of Canada] Centre for Disease Control1. Disinfecting commonly touched surfaces helps to reduce the spread of harmful germs by our hands, but would require manual and repeated disinfection because germs grow rapidly. Current disinfectants may also contain chemicals like triclosan which are not recognized as safe and effective 2, and may lead to bacterial resistance and environmental contamination if used extensively.

“There is an urgent need for a better way to disinfect surfaces without causing bacterial resistance or harm to the environment. This will help us to prevent the transmission of infectious diseases from contact with surfaces,” said IBN Executive Director Professor Jackie Y. Ying.

To tackle this problem, a team of researchers led by IBN Group Leader Dr Yugen Zhang created a novel nano coating that can spontaneously kill bacteria upon contact. Inspired by studies on dragonflies and cicadas, the IBN scientists grew nanopilllars of zinc oxide, a compound known for its anti-bacterial and non-toxic properties. The zinc oxide nanopillars can kill a broad range of germs like E. coli and S. aureus that are commonly transmitted from surface contact.

Tests on ceramic, glass, titanium and zinc surfaces showed that the coating effectively killed up to 99.9% of germs found on the surfaces. As the bacteria are killed mechanically rather than chemically, the use of the nano coating would not contribute to environmental pollution. Also, the bacteria will not be able to develop resistance as they are completely destroyed when their cell walls are pierced by the nanopillars upon contact.

Further studies revealed that the nano coating demonstrated the best bacteria killing power when it is applied on zinc surfaces, compared with other surfaces. This is because the zinc oxide nanopillars catalyzed the release of superoxides (or reactive oxygen species), which could even kill nearby free floating bacteria that were not in direct contact with the surface. This super bacteria killing power from the combination of nanopillars and zinc broadens the scope of applications of the coating beyond hard surfaces.

Subsequently, the researchers studied the effect of placing a piece of zinc that had been coated with zinc oxide nanopillars into water containing E. coli. All the bacteria were killed, suggesting that this material could potentially be used for water purification.

Dr Zhang said, “Our nano coating is designed to disinfect surfaces in a novel yet practical way. This study demonstrated that our coating can effectively kill germs on different types of surfaces, and also in water. We were also able to achieve super bacteria killing power when the coating was used on zinc surfaces because of its dual mechanism of action. We hope to use this technology to create bacteria-free surfaces in a safe, inexpensive and effective manner, especially in places where germs tend to accumulate.”

IBN has recently received a grant from the National Research Foundation, Prime Minister’s Office, Singapore, under its Competitive Research Programme to further develop this coating technology in collaboration with Tan Tock Seng Hospital for commercial application over the next 5 years.

1 B.C. Centre for Disease Control

2 U.S. Food & Drug Administration

(I wasn’t expecting to see a reference to my home province [BC Centre for Disease Control].) Back to the usual, here’s a link to and a citation for the paper,

ZnO Nanopillar Coated Surfaces with Substrate‐Dependent Superbactericidal Property by Guangshun Yi, Yuan Yuan, Xiukai Li, Yugen Zhang. Small https://doi.org/10.1002/smll.201703159 First published: 22 February 2018

This paper is behind a paywall.

One final comment, this research reminds me of research into simulating shark skin because that too has bacteria-killing nanostructures. My latest about the sharkskin research is a Sept, 18, 2014 posting.

University of Twente (Holland) researchers love their metaphors: ‘bed of nails’ and ‘soccer balls’

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In the last week there have been a couple of news releases from Dutch researchers at the University of Twente’s MESA+ Institute for Nanotechnology which feature some metaphors. The first was a Sept. 20, 2012 news item on Nanowerk (Note: I have removed a link),

Nanotechnology researchers develop ‘bed of nails’ material for clean surfaces

Scientists at the University of Twente’s MESA+ Institute for Nanotechnology have developed a new material that is not only extremely water-repellent but also extremely oil-repellent. It contains minuscule pillars which retain droplets. What makes the material unique is that the droplets stay on top even when they evaporate (slowly getting smaller). This opens the way to such things as smartphone screens that really cannot get dirty. The study appears today in the scientific journal Soft Matter (“Absence of an evaporation-driven wetting transition on omniphobic surfaces”).

The University of Twente Sept. 12, 2012 news release, which originated the news item explores the metaphor and the technology,

Water-repellent surfaces can be used as a coating for windows, obviating the need to clean them ever again. These surfaces have an orderly arrangement of tiny pillars less than one-hundredth of a millimetre high (similar to a bed of nails but on an extremely small scale). Water droplets stay on the tips of the pillars, retaining the shape of perfectly round tiny pearls. As a result they can roll off the surface like marbles, taking all the dirt with them.

Nanotechnologists at the University of Twente have now managed to create a silicon surface that retains not only water droplets but also oil droplets like tiny pearls …. What makes the material unique is that the droplets remain in place even when they evaporate (get smaller).

With existing materials, evaporating droplets drop down between the pillars onto the surface after a while, changing in shape to hemispheres which can no longer simply roll off the surface. The surface can therefore still get dirty. By modifying the edges and the roughness of the minuscule pillars the UT scientists have managed to create a surface on which the droplets do not drop down even when they evaporate but stay neatly on top.

The Sept. 27, 2012 news item on Nanowerk features another metaphor, one which is well known amongst followers of the nanotechnology scene,

Nanotechnologists create miniscule soccer balls

Nanotechnologists at the University of Twente’s MESA+ research institute have developed a method whereby minuscule polystyrene spheres, automatically and under controlled conditions, form an almost perfect ball that looks suspiciously like a football, but about a thousand times smaller. The spheres organize themselves in such a way that they approach the densest arrangement possible, known as ‘closest packing of spheres’. The method provides nanotechnologists with a new way of creating minuscule 3D structures.

Soccer balls usually reference buckminster fullerenes (bucky balls). The news item explains this new use further,

The method developed by the University of Twente scientists involves placing a drop of water containing thousands of polystyrene spheres one micrometre in size (a thousand times smaller than a millimetre) on a superhydrophobic surface. As the drop is allowed to evaporate very slowly under controlled conditions the distances between the spheres become smaller and smaller and surprisingly they form a highly organized 3D structure. The spheres were found to organize themselves of their own accord in such a way that the ball they form approaches the most compact arrangement possible (‘closest packing of spheres’), with 74% of the space filled by the spheres. Like a football, the structures that form are almost perfectly spherical, consisting of a large number of planes. The researchers have therefore dubbed their material ‘microscopic soccer balls’. The minuscule footballs are a hundred to a thousand micrometres in size, containing from ten thousand to as much as a billion of the tiny polystyrene spheres.

There’s more on the University of Twente’s MESA+ Institute for Nanotechnology website but you will need to have Dutch language skills.

It’s always good to see metaphors and I like when scientists (or whoever’s writing the news releases) get create that way.