Tag Archives: Brad Smith

China’s ex-UK ambassador clashes with ‘AI godfather’ on panel at AI Action Summit in France (February 10 – 11, 2025)

The Artificial Intelligence (AI) Action Summit held from February 10 – 11, 2025 in Paris seems to have been pretty exciting, President Emanuel Macron announced a 09B euros investment in the French AI sector on February 10, 2025 (I have more in my February 13, 2025 posting [scroll down to the ‘What makes Canadian (and Greenlandic) minerals and water so important?’ subhead]). I also have this snippet, which suggests Macron is eager to provide an alternative to US domination in the field of AI, from a February 10, 2025 posting on CCGTN (China Global Television Network),

French President Emmanuel Macron announced on Sunday night [February 10, 2025] that France is set to receive a total investment of 109 billion euros (approximately $112 billion) in artificial intelligence over the coming years.

Speaking in a televised interview on public broadcaster France 2, Macron described the investment as “the equivalent for France of what the United States announced with ‘Stargate’.”

He noted that the funding will come from the United Arab Emirates, major American and Canadian investment funds [emphases mine], as well as French companies.

Prime Minister Justin Trudeau attended the AI Action Summit on Tuesday, February 11, 2025 according to a Canadian Broadcasting Corporation (CBC) news online article by Ashley Burke and Olivia Stefanovich,

Prime Minister Justin Trudeau warned U.S. Vice-President J.D. Vance that punishing tariffs on Canadian steel and aluminum will hurt his home state of Ohio, a senior Canadian official said. 

The two leaders met on the sidelines of an international summit in Paris Tuesday [February 11, 2025], as the Trump administration moves forward with its threat to impose 25 per cent tariffs on all steel and aluminum imports, including from its biggest supplier, Canada, effective March 12.

Speaking to reporters on Wednesday [February 12, 2025] as he departed from Brussels, Trudeau characterized the meeting as a brief chat that took place as the pair met.

“It was just a quick greeting exchange,” Trudeau said. “I highlighted that $2.2 billion worth of steel and aluminum exports from Canada go directly into the Ohio economy, often to go into manufacturing there.

“He nodded, and noted it, but it wasn’t a longer exchange than that.”

Vance didn’t respond to Canadian media’s questions about the tariffs while arriving at the summit on Tuesday [February 11, 2025].

Additional insight can be gained from a February 10, 2025 PBS (US Public Broadcasting Service) posting of an AP (Associated Press) article with contributions from Kelvin Chan and Angela Charlton in Paris, Ken Moritsugu in Beijing, and Aijaz Hussain in New Delhi,

JD Vance stepped onto the world stage this week for the first time as U.S. vice president, using a high-stakes AI summit in Paris and a security conference in Munich to amplify Donald Trump’s aggressive new approach to diplomacy.

The 40-year-old vice president, who was just 18 months into his tenure as a senator before joining Trump’s ticket, is expected, while in Paris, to push back on European efforts to tighten AI oversight while advocating for a more open, innovation-driven approach.

The AI summit has drawn world leaders, top tech executives, and policymakers to discuss artificial intelligence’s impact on global security, economics, and governance. High-profile attendees include Chinese Vice Premier Zhang Guoqing, signaling Beijing’s deep interest in shaping global AI standards.

Macron also called on “simplifying” rules in France and the European Union to allow AI advances, citing sectors like healthcare, mobility, energy, and “resynchronize with the rest of the world.”

“We are most of the time too slow,” he said.

The summit underscores a three-way race for AI supremacy: Europe striving to regulate and invest, China expanding access through state-backed tech giants, and the U.S. under Trump prioritizing a hands-off approach.

Vance has signaled he will use the Paris summit as a venue for candid discussions with world leaders on AI and geopolitics.

“I think there’s a lot that some of the leaders who are present at the AI summit could do to, frankly — bring the Russia-Ukraine conflict to a close, help us diplomatically there — and so we’re going to be focused on those meetings in France,” Vance told Breitbart News.

Vance is expected to meet separately Tuesday with Indian Prime Minister Narendra Modi and European Commission President Ursula von der Leyen, according to a person familiar with planning who spoke on the condition of anonymity.

Modi is co-hosting the summit with Macron in an effort to prevent the sector from becoming a U.S.-China battle.

Indian Foreign Secretary Vikram Misri stressed the need for equitable access to AI to avoid “perpetuating a digital divide that is already existing across the world.”

But the U.S.-China rivalry overshadowed broader international talks.

The U.S.-China rivalry didn’t entirely overshadow the talks. At least one Chinese former diplomat chose to make her presence felt by chastising a Canadian academic according to a February 11, 2025 article by Matthew Broersma for silicon.co.uk

A representative of China at this week’s AI Action Summit in Paris stressed the importance of collaboration on artificial intelligence, while engaging in a testy exchange with Yoshua Bengio, a Canadian academic considered one of the “Godfathers” of AI.

Fu Ying, a former Chinese government official and now an academic at Tsinghua University in Beijing, said the name of China’s official AI Development and Safety Network was intended to emphasise the importance of collaboration to manage the risks around AI.

She also said tensions between the US and China were impeding the ability to develop AI safely.

… Fu Ying, a former vice minister of foreign affairs in China and the country’s former UK ambassador, took veiled jabs at Prof Bengio, who was also a member of the panel.

Zoe Kleinman’s February 10, 2025 article for the British Broadcasting Corporation (BBC) news online website also notes the encounter,

A former Chinese official poked fun at a major international AI safety report led by “AI Godfather” professor Yoshua Bengio and co-authored by 96 global experts – in front of him.

Fu Ying, former vice minister of foreign affairs and once China’s UK ambassador, is now an academic at Tsinghua University in Beijing.

The pair were speaking at a panel discussion ahead of a two-day global AI summit starting in Paris on Monday [February 10, 2025].

The aim of the summit is to unite world leaders, tech executives, and academics to examine AI’s impact on society, governance, and the environment.

Fu Ying began by thanking Canada’s Prof Bengio for the “very, very long” document, adding that the Chinese translation stretched to around 400 pages and she hadn’t finished reading it.

She also had a dig at the title of the AI Safety Institute – of which Prof Bengio is a member.

China now has its own equivalent; but they decided to call it The AI Development and Safety Network, she said, because there are lots of institutes already but this wording emphasised the importance of collaboration.

The AI Action Summit is welcoming guests from 80 countries, with OpenAI chief executive Sam Altman, Microsoft president Brad Smith and Google chief executive Sundar Pichai among the big names in US tech attending.

Elon Musk is not on the guest list but it is currently unknown whether he will decide to join them. [As of February 13, 2025, Mr. Musk did not attend the summit, which ended February 11, 2025.]

A key focus is regulating AI in an increasingly fractured world. The summit comes weeks after a seismic industry shift as China’s DeepSeek unveiled a powerful, low-cost AI model, challenging US dominance.

The pair’s heated exchanges were a symbol of global political jostling in the powerful AI arms race, but Fu Ying also expressed regret about the negative impact of current hostilities between the US and China on the progress of AI safety.

She gave a carefully-crafted glimpse behind the curtain of China’s AI scene, describing an “explosive period” of innovation since the country first published its AI development plan in 2017, five years before ChatGPT became a viral sensation in the west.

She added that “when the pace [of development] is rapid, risky stuff occurs” but did not elaborate on what might have taken place.

“The Chinese move faster [than the west] but it’s full of problems,” she said.

Fu Ying argued that building AI tools on foundations which are open source, meaning everyone can see how they work and therefore contribute to improving them, was the most effective way to make sure the tech did not cause harm.

Most of the US tech giants do not share the tech which drives their products.

Open source offers humans “better opportunities to detect and solve problems”, she said, adding that “the lack of transparency among the giants makes people nervous”.

But Prof Bengio disagreed.

His view was that open source also left the tech wide open for criminals to misuse.

He did however concede that “from a safety point of view”, it was easier to spot issues with the viral Chinese AI assistant DeepSeek, which was built using open source architecture, than ChatGPT, whose code has not been shared by its creator OpenAI.

Fro anyone curious about Professor Bengio’s AI safety report, I have more information in a September 29, 2025 Université de Montréal (UdeM) press release,

The first international report on the safety of artificial intelligence, led by Université de Montréal computer-science professor Yoshua Bengio, was released today and promises to serve as a guide for policymakers worldwide. 

Announced in November 2023 at the AI Safety Summit at Bletchley Park, England, and inspired by the workings of the United Nations Intergovernmental Panel on Climate Change, the report consolidates leading international expertise on AI and its risks. 

Supported by the United Kingdom’s Department for Science, Innovation and Technology, Bengio, founder and scientific director of the UdeM-affiliated Mila – Quebec AI Institute, led a team of 96 international experts in drafting the report.

The experts were drawn from 30 countries, the U.N., the European Union and the OECD [Organisation for Economic Cooperation and Development]. Their report will help inform discussions next month at the AI Action Summit in Paris, France and serve as a global handbook on AI safety to help support policymakers.

Towards a common understanding

The most advanced AI systems in the world now have the ability to write increasingly sophisticated computer programs, identify cyber vulnerabilities, and perform on a par with human PhD-level experts on tests in biology, chemistry, and physics. 

In what is identified as a key development for policymakers to monitor, the AI Safety Report published today warns that AI systems are also increasingly capable of acting as AI agents, autonomously planning and acting in pursuit of a goal. 

As policymakers worldwide grapple with the rapid and unpredictable advancements in AI, the report contributes to bridging the gap by offering a scientific understanding of emerging risks to guide decision-making.  

The document sets out the first comprehensive, independent, and shared scientific understanding of advanced AI systems and their risks, highlighting how quickly the technology has evolved.  

Several areas require urgent research attention, according to the report, including how rapidly capabilities will advance, how general-purpose AI models work internally, and how they can be designed to behave reliably. 

Three distinct categories of AI risks are identified: 

  • Malicious use risks: these include cyberattacks, the creation of AI-generated child-sexual-abuse material, and even the development of biological weapons; 
  • System malfunctions: these include bias, reliability issues, and the potential loss of control over advanced general-purpose AI systems; 
  • Systemic risks: these stem from the widespread adoption of AI, include workforce disruption, privacy concerns, and environmental impacts.  

The report places particular emphasis on the urgency of increasing transparency and understanding in AI decision-making as the systems become more sophisticated and the technology continues to develop at a rapid pace. 

While there are still many challenges in mitigating the risks of general-purpose AI, the report highlights promising areas for future research and concludes that progress can be made.   

Ultimately, it emphasizes that while AI capabilities could advance at varying speeds, their development and potential risks are not a foregone conclusion. The outcomes depend on the choices that societies and governments make today and in the future. 

“The capabilities of general-purpose AI have increased rapidly in recent years and months,” said Bengio. “While this holds great potential for society, AI also presents significant risks that must be carefully managed by governments worldwide.  

“This report by independent experts aims to facilitate constructive and evidence-based discussion around these risks and serves as a common basis for policymakers around the world to understand general-purpose AI capabilities, risks and possible mitigations.” 

The report is more formally known as the International AI Safety Report 2025 and can be found on the gov.uk website.

There have been two previous AI Safety Summits that I’m aware of and you can read about them in my May 21, 2024 posting about the one in Korea and in my November 2, 2023 posting about the first summit at Bletchley Park in the UK.

You can find the Canadian Artificial Intelligence Safety Institute (or AI Safety Institute) here and my coverage of DeepSeek’s release and the panic in the US artificial intelligence and the business communities that ensued in my January 29, 2025 posting.

Technical University of Munich: embedded ethics approach for AI (artificial intelligence) and storing a tv series in synthetic DNA

I stumbled across two news bits of interest from the Technical University of Munich in one day (Sept. 1, 2020, I think). The topics: artificial intelligence (AI) and synthetic DNA (deoxyribonucleic acid).

Embedded ethics and artificial intelligence (AI)

An August 27, 2020 Technical University of Munich (TUM) press release (also on EurekAlert but published Sept. 1, 2020) features information about a proposal to embed ethicists in with AI development teams,

The increasing use of AI (artificial intelligence) in the development of new medical technologies demands greater attention to ethical aspects. An interdisciplinary team at the Technical University of Munich (TUM) advocates the integration of ethics from the very beginning of the development process of new technologies. Alena Buyx, Professor of Ethics in Medicine and Health Technologies, explains the embedded ethics approach.

Professor Buyx, the discussions surrounding a greater emphasis on ethics in AI research have greatly intensified in recent years, to the point where one might speak of “ethics hype” …

Prof. Buyx: … and many committees in Germany and around the world such as the German Ethics Council or the EU Commission High-Level Expert Group on Artificial Intelligence have responded. They are all in agreement: We need more ethics in the development of AI-based health technologies. But how do things look in practice for engineers and designers? Concrete solutions are still few and far between. In a joint pilot project with two Integrative Research Centers at TUM, the Munich School of Robotics and Machine Intelligence (MSRM) with its director, Prof. Sami Haddadin, and the Munich Center for Technology in Society (MCTS), with Prof. Ruth Müller, we want to try out the embedded ethics approach. We published the proposal in Nature Machine Intelligence at the end of July [2020].

What exactly is meant by the “embedded ethics approach”?

Prof.Buyx: The idea is to make ethics an integral part of the research process by integrating ethicists into the AI development team from day one. For example, they attend team meetings on a regular basis and create a sort of “ethical awareness” for certain issues. They also raise and analyze specific ethical and social issues.

Is there an example of this concept in practice?

Prof. Buyx: The Geriatronics Research Center, a flagship project of the MSRM in Garmisch-Partenkirchen, is developing robot assistants to enable people to live independently in old age. The center’s initiatives will include the construction of model apartments designed to try out residential concepts where seniors share their living space with robots. At a joint meeting with the participating engineers, it was noted that the idea of using an open concept layout everywhere in the units – with few doors or individual rooms – would give the robots considerable range of motion. With the seniors, however, this living concept could prove upsetting because they are used to having private spaces. At the outset, the engineers had not given explicit consideration to this aspect.

Prof.Buyx: The approach sounds promising. But how can we avoid “embedded ethics” from turning into an “ethics washing” exercise, offering companies a comforting sense of “being on the safe side” when developing new AI technologies?

That’s not something we can be certain of avoiding. The key is mutual openness and a willingness to listen, with the goal of finding a common language – and subsequently being prepared to effectively implement the ethical aspects. At TUM we are ideally positioned to achieve this. Prof. Sami Haddadin, the director of the MSRM, is also a member of the EU High-Level Group of Artificial Intelligence. In his research, he is guided by the concept of human centered engineering. Consequently, he has supported the idea of embedded ethics from the very beginning. But one thing is certain: Embedded ethics alone will not suddenly make AI “turn ethical”. Ultimately, that will require laws, codes of conduct and possibly state incentives.

Here’s a link to and a citation for the paper espousing the embedded ethics for AI development approach,

An embedded ethics approach for AI development by Stuart McLennan, Amelia Fiske, Leo Anthony Celi, Ruth Müller, Jan Harder, Konstantin Ritt, Sami Haddadin & Alena Buyx. Nature Machine Intelligence (2020) DOI: https://doi.org/10.1038/s42256-020-0214-1 Published 31 July 2020

This paper is behind a paywall.

Religion, ethics and and AI

For some reason embedded ethics and AI got me to thinking about Pope Francis and other religious leaders.

The Roman Catholic Church and AI

There was a recent announcement that the Roman Catholic Church will be working with MicroSoft and IBM on AI and ethics (from a February 28, 2020 article by Jen Copestake for British Broadcasting Corporation (BBC) news online (Note: A link has been removed),

Leaders from the two tech giants met senior church officials in Rome, and agreed to collaborate on “human-centred” ways of designing AI.

Microsoft president Brad Smith admitted some people may “think of us as strange bedfellows” at the signing event.

“But I think the world needs people from different places to come together,” he said.

The call was supported by Pope Francis, in his first detailed remarks about the impact of artificial intelligence on humanity.

The Rome Call for Ethics [sic] was co-signed by Mr Smith, IBM executive vice-president John Kelly and president of the Pontifical Academy for Life Archbishop Vincenzo Paglia.

It puts humans at the centre of new technologies, asking for AI to be designed with a focus on the good of the environment and “our common and shared home and of its human inhabitants”.

Framing the current era as a “renAIssance”, the speakers said the invention of artificial intelligence would be as significant to human development as the invention of the printing press or combustion engine.

UN Food and Agricultural Organization director Qu Dongyu and Italy’s technology minister Paola Pisano were also co-signatories.

Hannah Brockhaus’s February 28, 2020 article for the Catholic News Agency provides some details missing from the BBC report and I found it quite helpful when trying to understand the various pieces that make up this initiative,

The Pontifical Academy for Life signed Friday [February 28, 2020], alongside presidents of IBM and Microsoft, a call for ethical and responsible use of artificial intelligence technologies.

According to the document, “the sponsors of the call express their desire to work together, in this context and at a national and international level, to promote ‘algor-ethics.’”

“Algor-ethics,” according to the text, is the ethical use of artificial intelligence according to the principles of transparency, inclusion, responsibility, impartiality, reliability, security, and privacy.

The signing of the “Rome Call for AI Ethics [PDF]” took place as part of the 2020 assembly of the Pontifical Academy for Life, which was held Feb. 26-28 [2020] on the theme of artificial intelligence.

One part of the assembly was dedicated to private meetings of the academics of the Pontifical Academy for Life. The second was a workshop on AI and ethics that drew 356 participants from 41 countries.

On the morning of Feb. 28 [2020], a public event took place called “renAIssance. For a Humanistic Artificial Intelligence” and included the signing of the AI document by Microsoft President Brad Smith, and IBM Executive Vice-president John Kelly III.

The Director General of FAO, Dongyu Qu, and politician Paola Pisano, representing the Italian government, also signed.

The president of the European Parliament, David Sassoli, was also present Feb. 28.

Pope Francis canceled his scheduled appearance at the event due to feeling unwell. His prepared remarks were read by Archbishop Vincenzo Paglia, president of the Academy for Life.

You can find Pope Francis’s comments about the document here (if you’re not comfortable reading Italian, hopefully, the English translation which follows directly afterward will be helpful). The Pope’s AI initiative has a dedicated website, Rome Call for AI ethics, and while most of the material dates from the February 2020 announcement, they are keeping up a blog. It has two entries, one dated in May 2020 and another in September 2020.

Buddhism and AI

The Dalai Lama is well known for having an interest in science and having hosted scientists for various dialogues. So, I was able to track down a November 10, 2016 article by Ariel Conn for the futureoflife.org website, which features his insights on the matter,

The question of what it means and what it takes to feel needed is an important problem for ethicists and philosophers, but it may be just as important for AI researchers to consider. The Dalai Lama argues that lack of meaning and purpose in one’s work increases frustration and dissatisfaction among even those who are gainfully employed.

“The problem,” says the Dalai Lama, “is … the growing number of people who feel they are no longer useful, no longer needed, no longer one with their societies. … Feeling superfluous is a blow to the human spirit. It leads to social isolation and emotional pain, and creates the conditions for negative emotions to take root.”

If feeling needed and feeling useful are necessary for happiness, then AI researchers may face a conundrum. Many researchers hope that job loss due to artificial intelligence and automation could, in the end, provide people with more leisure time to pursue enjoyable activities. But if the key to happiness is feeling useful and needed, then a society without work could be just as emotionally challenging as today’s career-based societies, and possibly worse.

I also found a talk on the topic by The Venerable Tenzin Priyadarshi, first here’s a description from his bio at the Dalai Lama Center for Ethics and Transformative Values webspace on the Massachusetts Institute of Technology (MIT) website,

… an innovative thinker, philosopher, educator and a polymath monk. He is Director of the Ethics Initiative at the MIT Media Lab and President & CEO of The Dalai Lama Center for Ethics and Transformative Values at the Massachusetts Institute of Technology. Venerable Tenzin’s unusual background encompasses entering a Buddhist monastery at the age of ten and receiving graduate education at Harvard University with degrees ranging from Philosophy to Physics to International Relations. He is a Tribeca Disruptive Fellow and a Fellow at the Center for Advanced Study in Behavioral Sciences at Stanford University. Venerable Tenzin serves on the boards of a number of academic, humanitarian, and religious organizations. He is the recipient of several recognitions and awards and received Harvard’s Distinguished Alumni Honors for his visionary contributions to humanity.

He gave the 2018 Roger W. Heyns Lecture in Religion and Society at Stanford University on the topic, “Religious and Ethical Dimensions of Artificial Intelligence.” The video runs over one hour but he is a sprightly speaker (in comparison to other Buddhist speakers I’ve listened to over the years).

Judaism, Islam, and other Abrahamic faiths examine AI and ethics

I was delighted to find this January 30, 2020 Artificial Intelligence: Implications for Ethics and Religion event as it brought together a range of thinkers from various faiths and disciplines,

New technologies are transforming our world every day, and the pace of change is only accelerating.  In coming years, human beings will create machines capable of out-thinking us and potentially taking on such uniquely-human traits as empathy, ethical reasoning, perhaps even consciousness.  This will have profound implications for virtually every human activity, as well as the meaning we impart to life and creation themselves.  This conference will provide an introduction for non-specialists to Artificial Intelligence (AI):

What is it?  What can it do and be used for?  And what will be its implications for choice and free will; economics and worklife; surveillance economies and surveillance states; the changing nature of facts and truth; and the comparative intelligence and capabilities of humans and machines in the future? 

Leading practitioners, ethicists and theologians will provide cross-disciplinary and cross-denominational perspectives on such challenges as technology addiction, inherent biases and resulting inequalities, the ethics of creating destructive technologies and of turning decision-making over to machines from self-driving cars to “autonomous weapons” systems in warfare, and how we should treat the suffering of “feeling” machines.  The conference ultimately will address how we think about our place in the universe and what this means for both religious thought and theological institutions themselves.

UTS [Union Theological Seminary] is the oldest independent seminary in the United States and has long been known as a bastion of progressive Christian scholarship.  JTS [Jewish Theological Seminary] is one of the academic and spiritual centers of Conservative Judaism and a major center for academic scholarship in Jewish studies. The Riverside Church is an interdenominational, interracial, international, open, welcoming, and affirming church and congregation that has served as a focal point of global and national activism for peace and social justice since its inception and continues to serve God through word and public witness. The annual Greater Good Gathering, the following week at Columbia University’s School of International & Public Affairs, focuses on how technology is changing society, politics and the economy – part of a growing nationwide effort to advance conversations promoting the “greater good.”

They have embedded a video of the event (it runs a little over seven hours) on the January 30, 2020 Artificial Intelligence: Implications for Ethics and Religion event page. For anyone who finds that a daunting amount of information, you may want to check out the speaker list for ideas about who might be writing and thinking on this topic.

As for Islam, I did track down this November 29, 2018 article by Shahino Mah Abdullah, a fellow at the Institute of Advanced Islamic Studies (IAIS) Malaysia,

As the global community continues to work together on the ethics of AI, there are still vast opportunities to offer ethical inputs, including the ethical principles based on Islamic teachings.

This is in line with Islam’s encouragement for its believers to convey beneficial messages, including to share its ethical principles with society.

In Islam, ethics or akhlak (virtuous character traits) in Arabic, is sometimes employed interchangeably in the Arabic language with adab, which means the manner, attitude, behaviour, and etiquette of putting things in their proper places. Islamic ethics cover all the legal concepts ranging from syariah (Islamic law), fiqh ( jurisprudence), qanun (ordinance), and ‘urf (customary practices).

Adopting and applying moral values based on the Islamic ethical concept or applied Islamic ethics could be a way to address various issues in today’s societies.

At the same time, this approach is in line with the higher objectives of syariah (maqasid alsyariah) that is aimed at conserving human benefit by the protection of human values, including faith (hifz al-din), life (hifz alnafs), lineage (hifz al-nasl), intellect (hifz al-‘aql), and property (hifz al-mal). This approach could be very helpful to address contemporary issues, including those related to the rise of AI and intelligent robots.

..

Part of the difficulty with tracking down more about AI, ethics, and various religions is linguistic. I simply don’t have the language skills to search for the commentaries and, even in English, I may not have the best or most appropriate search terms.

Television (TV) episodes stored on DNA?

According to a Sept. 1, 2020 news item on Nanowerk, the first episode of a tv series, ‘Biohackers’ has been stored on synthetic DNA (deoxyribonucleic acid) by a researcher at TUM and colleagues at another institution,

The first episode of the newly released series “Biohackers” was stored in the form of synthetic DNA. This was made possible by the research of Prof. Reinhard Heckel of the Technical University of Munich (TUM) and his colleague Prof. Robert Grass of ETH Zürich.

They have developed a method that permits the stable storage of large quantities of data on DNA for over 1000 years.

A Sept. 1, 2020 TUM press release, which originated the news item, proceeds with more detail in an interview format,

Prof. Heckel, Biohackers is about a medical student seeking revenge on a professor with a dark past – and the manipulation of DNA with biotechnology tools. You were commissioned to store the series on DNA. How does that work?

First, I should mention that what we’re talking about is artificially generated – in other words, synthetic – DNA. DNA consists of four building blocks: the nucleotides adenine (A), thymine (T), guanine (G) and cytosine (C). Computer data, meanwhile, are coded as zeros and ones. The first episode of Biohackers consists of a sequence of around 600 million zeros and ones. To code the sequence 01 01 11 00 in DNA, for example, we decide which number combinations will correspond to which letters. For example: 00 is A, 01 is C, 10 is G and 11 is T. Our example then produces the DNA sequence CCTA. Using this principle of DNA data storage, we have stored the first episode of the series on DNA.

And to view the series – is it just a matter of “reverse translation” of the letters?

In a very simplified sense, you can visualize it like that. When writing, storing and reading the DNA, however, errors occur. If these errors are not corrected, the data stored on the DNA will be lost. To solve the problem, I have developed an algorithm based on channel coding. This method involves correcting errors that take place during information transfers. The underlying idea is to add redundancy to the data. Think of language: When we read or hear a word with missing or incorrect letters, the computing power of our brain is still capable of understanding the word. The algorithm follows the same principle: It encodes the data with sufficient redundancy to ensure that even highly inaccurate data can be restored later.

Channel coding is used in many fields, including in telecommunications. What challenges did you face when developing your solution?

The first challenge was to create an algorithm specifically geared to the errors that occur in DNA. The second one was to make the algorithm so efficient that the largest possible quantities of data can be stored on the smallest possible quantity of DNA, so that only the absolutely necessary amount of redundancy is added. We demonstrated that our algorithm is optimized in that sense.

DNA data storage is very expensive because of the complexity of DNA production as well as the reading process. What makes DNA an attractive storage medium despite these challenges?

First, DNA has a very high information density. This permits the storage of enormous data volumes in a minimal space. In the case of the TV series, we stored “only” 100 megabytes on a picogram – or a billionth of a gram of DNA. Theoretically, however, it would be possible to store up to 200 exabytes on one gram of DNA. And DNA lasts a long time. By comparison: If you never turned on your PC or wrote data to the hard disk it contains, the data would disappear after a couple of years. By contrast, DNA can remain stable for many thousands of years if it is packed right.

And the method you have developed also makes the DNA strands durable – practically indestructible.

My colleague Robert Grass was the first to develop a process for the “stable packing” of DNA strands by encapsulating them in nanometer-scale spheres made of silica glass. This ensures that the DNA is protected against mechanical influences. In a joint paper in 2015, we presented the first robust DNA data storage concept with our algorithm and the encapsulation process developed by Prof. Grass. Since then we have continuously improved our method. In our most recent publication in Nature Protocols of January 2020, we passed on what we have learned.

What are your next steps? Does data storage on DNA have a future?

We’re working on a way to make DNA data storage cheaper and faster. “Biohackers” was a milestone en route to commercialization. But we still have a long way to go. If this technology proves successful, big things will be possible. Entire libraries, all movies, photos, music and knowledge of every kind – provided it can be represented in the form of data – could be stored on DNA and would thus be available to humanity for eternity.

Here’s a link to and a citation for the paper,

Reading and writing digital data in DNA by Linda C. Meiser, Philipp L. Antkowiak, Julian Koch, Weida D. Chen, A. Xavier Kohll, Wendelin J. Stark, Reinhard Heckel & Robert N. Grass. Nature Protocols volume 15, pages86–101(2020) Issue Date: January 2020 DOI: https://doi.org/10.1038/s41596-019-0244-5 Published [online] 29 November 2019

This paper is behind a paywall.

As for ‘Biohackers’, it’s a German science fiction television series and you can find out more about it here on the Internet Movie Database.

High speed rail link for Cascadia Innovation Corridor

In a Feb. 28, 2017 posting I featured an announcement about what I believe is the first  project from the British Columbia (province of Canada) and Washington State (US) government’s joint Cascadia Innovation Corridor initiative:  the Cascadia Analytics Cooperative, During the telephone press conference a couple of the participants joked about hyperloop (transportation pods in vacuum tubes) and  being able to travel between Vancouver (Canada) and Seattle (US) in minutes. It seems that might not have been quite the joke I assumed. Kenneth Chan in an Aug. 14, 2017 posting for the Daily Hive announced a high-speed rail feasibility study is underway (Note: Links have been removed),

According to KUOW public radio, the study began in late-July and will be conducted by a consultant at a cost of US$300,000 – down from the budgeted USD$1 million when the study was first announced earlier this year in Governor Jay Inslee’s proposed state budget. The budget bill proposed Washington State stations at locations such as Bellingham, Everett, SeaTac International Airport, Tacoma, Olympia, and Vancouver, Washington.

The idea has received the full backing of Washington State-based Microsoft, which supported the study with an additional $50,000 contribution. [emphasis mine] Engineering consultancy firm CH2M, which has offices in Vancouver, Seattle, and Portland, has been contracted to perform the study.

Interest in such a rail link is spurred from the Cascadia Innovation Corridor agreement signed by the government leaders of BC and Washington State last fall. The agreement committed both jurisdictions to growing the Vancouver-Seattle corridor into a tech corridor and innovation hub and improving transportation connections, such as high-speed rail.

“Why not a high speed train from Vancouver to Seattle to Portland? If we lived in Europe it would already be there,” said Brad Smith, Microsoft President and Chief Legal Officer, at a recent Portland conference on regional policy. “We need to raise our sights and our ambition level as a region.”

Microsoft is very interested in facilitating greater ease of movement, a development which causes me to to feel some unease as mentioned in my February 28, 2017 posting,

I look forward to hearing more about the Cascadia Urban Analytics Cooperative and the Cascadia Innovation Corridor as they develop. This has the potential to be very exciting although I do have some concerns such as MIcrosoft and its agendas, both stated and unstated. After all, the Sept. 2016 meeting was convened by Microsoft and its public affairs/lobbying group and the topic was innovation, which is code for business and as hinted earlier, business is not synonymous with social good. Having said that I’m not about to demonize business either. I just think a healthy dose of skepticism is called for. Good things can happen but we need to ensure they do.

Since February 2017, the government in British Columbia has changed hands and is now led by James Horgan of the New Democratic Party. Like Christy Clark and the Liberals before them, this provincial government does not have any science policy, a ministry of science (senior or junior), or any evidence of independent science advice. There has been (and may still be, it’s hard to tell) a Premier’s Technology Council, a BC Innovation Council (formerly the Science Council of BC), and #BCTECH Strategy which hie more to business and applied science than an inclusive ‘science strategy’ with attendant government agencies.