Tag Archives: CFI

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report): 3 of 3

This is the final commentary on the report titled,(INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research). Part 1 of my commentary having provided some introductory material and first thoughts about the report, Part 2 offering more detailed thoughts; this part singles out ‘special cases’, sums up* my thoughts (circling back to ideas introduced in the first part), and offers link to other commentaries.

Special cases

Not all of the science funding in Canada is funneled through the four agencies designed for that purpose, (The Natural Sciences and Engineering Research Council (NSERC), Social Sciences and Humanities Research Council (SSHRC), Canadian Institutes of Health Research (CIHR) are known collectively as the tri-council funding agencies and are focused on disbursement of research funds received from the federal government. The fourth ‘pillar’ agency, the Canada Foundation for Innovation (CFI) is focused on funding for infrastructure and, technically speaking, is a 3rd party organization along with MITACS, CANARIE, the Perimeter Institute, and others.

In any event, there are also major research facilities and science initiatives which may receive direct funding from the federal government bypassing the funding agencies and, it would seem, peer review. For example, I featured this in my April 28, 2015 posting about the 2015 federal budget,

The $45 million announced for TRIUMF will support the laboratory’s role in accelerating science in Canada, an important investment in discovery research.

While the news about the CFI seems to have delighted a number of observers, it should be noted (as per Woodgett’s piece) that the $1.3B is to be paid out over six years ($220M per year, more or less) and the money won’t be disbursed until the 2017/18 fiscal year. As for the $45M designated for TRIUMF (Canada’s National Laboratory for Particle and Nuclear Physics), this is exciting news for the lab which seems to have bypassed the usual channels, as it has before, to receive its funding directly from the federal government. [emphases mine]

The Naylor report made this recommendation for Canada’s major research facilities, (MRF)

We heard from many who recommended that the federal government should manage its investments in “Big Science” in a more coordinated manner, with a cradle-to-grave perspective. The Panel agrees. Consistent with NACRI’s overall mandate, it should work closely with the CSA [Chief Science Advisor] in establishing a Standing Committee on Major Research Facilities (MRFs).

CFI defines a national research facility in the following way:

We define a national research facility as one that addresses the needs of a community of Canadian researchers representing a critical mass of users distributed across the country. This is done by providing shared access to substantial and advanced specialized equipment, services, resources, and scientific and technical personnel. The facility supports leading-edge research and technology development, and promotes the mobilization of knowledge and transfer of technology to society. A national research facility requires resource commitments well beyond the capacity of any one institution. A national research facility, whether single-sited, distributed or virtual, is specifically identified or recognized as serving pan-Canadian needs and its governance and management structures reflect this mandate.8

We accept this definition as appropriate for national research facilities to be considered by the Standing Committee on MRFs, but add that the committee should:

• define a capital investment or operating cost level above which such facilities are considered “major” and thus require oversight by this committee (e.g., defined so as to include the national MRFs proposed in Section 6.3: Compute Canada, Canadian Light Source, Canada’s National Design Network, Canadian Research Icebreaker Amundsen, International Vaccine Centre, Ocean Networks Canada, Ocean Tracking Network, and SNOLAB plus the TRIUMF facility); and

• consider international MRFs in which Canada has a significant role, such as astronomical telescopes of global significance.

The structure and function of this Special Standing Committee would closely track the proposal made in 2006 by former NSA [National Science Advisor] Dr Arthur Carty. We return to this topic in Chapter 6. For now, we observe that this approach would involve:

• a peer-reviewed decision on beginning an investment;

• a funded plan for the construction and operation of the facility, with continuing oversight by a peer specialist/agency review group for the specific facility;

• a plan for decommissioning; and

• a regular review scheduled to consider whether the facility still serves current needs.

We suggest that the committee have 10 members, with an eminent scientist as Chair. The members should include the CSA, two representatives from NACRI for liaison, and seven others. The other members should include Canadian and international scientists from a broad range of disciplines and experts on the construction, operation, and administration of MRFs. Consideration should be given to inviting the presidents of NRC [National Research Council of Canada] and CFI to serve as ex-officio members. The committee should be convened by the CSA, have access to the Secretariat associated with the CSA and NACRI, and report regularly to NACRI. (pp. 66-7 print; pp. 100-1 PDF)

I have the impression there’s been some ill feeling over the years regarding some of the major chunks of money given for ‘big science’. At a guess, direct appeals to a federal government that has no official mechanism for assessing the proposed ‘big science’ whether that means a major research facility (e.g., TRIUMF) or major science initiative (e.g., Pan Canadian Artificial Intelligence Strategy [keep reading to find out how I got the concept of a major science initiative wrong]) or 3rd party (MITACS) has seemed unfair to those who have to submit funding applications and go through vetting processes. This recommendation would seem to be an attempt to redress some of the issues.

Moving onto the third-party delivery and matching programs,

Three bodies in particular are the largest of these third-party organizations and illustrate the challenges of evaluating contribution agreements: Genome Canada, Mitacs, and Brain Canada. Genome Canada was created in 2000 at a time when many national genomics initiatives were being developed in the wake of the Human Genome Project. It emerged from a “bottom-up” design process driven by genomic scientists to complement existing programs by focusing on large-scale projects and technology platforms. Its funding model emphasized partnerships and matching funds to leverage federal commitments with the objective of rapidly ramping up genomics research in Canada.

This approach has been successful: Genome Canada has received $1.1 billion from the Government of Canada since its creation in 2000, and has raised over $1.6 billion through co-funding commitments, for a total investment in excess of $2.7 billion.34 The scale of Genome Canada’s funding programs allows it to support large-scale genomics research that the granting councils might otherwise not be able to fund. Genome Canada also supports a network of genomics technology and innovation centres with an emphasis on knowledge translation and has built domestic and international strategic partnerships. While its primary focus has been human health, it has also invested extensively in agriculture, forestry, fisheries, environment, and, more recently, oil and gas and mining— all with a view to the application and commercialization of genomic biotechnology.

Mitacs attracts, trains, and retains HQP [highly qualified personnel] in the Canadian research enterprise. Founded in 1999 as an NCE [Network Centre for Excellence], it was developed at a time when enrolments in graduate programs had flat-lined, and links between mathematics and industry were rare. Independent since 2011, Mitacs has focused on providing industrial research internships and postdoctoral fellowships, branching out beyond mathematics to all disciplines. It has leveraged funding effectively from the federal and provincial governments, industry, and not-for-profit organizations. It has also expanded internationally, providing two-way research mobility. Budget 2015 made Mitacs the single mechanism of federal support for postsecondary research internships with a total federal investment of $135.4 million over the next five years. This led to the wind-down of NSERC’s Industrial Postgraduate Scholarships Program. With matching from multiple other sources, Mitacs’ average annual budget is now $75 to $80 million. The organization aims to more than double the number of internships it funds to 10,000 per year by 2020.35

Finally, Brain Canada was created in 1998 (originally called NeuroScience Canada) to increase the scale of brain research funding in Canada and widen its scope with a view to encouraging interdisciplinary collaboration. In 2011 the federal government established the Canada Brain Research Fund to expand Brain Canada’s work, committing $100 million in new public investment for brain research to be matched 1:1 through contributions raised by Brain Canada. According to the STIC ‘State of the Nation’ 2014 report, Canada’s investment in neuroscience research is only about 40 per cent of that in the U.S. after adjusting for the size of the U.S. economy.36 Brain Canada may be filling a void left by declining success rates and flat funding at CIHR.

Recommendation and Elaboration

The Panel noted that, in general, third-party organizations for delivering research funding are particularly effective in leveraging funding from external partners. They fill important gaps in research funding and complement the work of the granting councils and CFI. At the same time, we questioned the overall efficiency of directing federal research funding through third-party organizations, noting that our consultations solicited mixed reactions. Some respondents favoured more overall funding concentrated in the agencies rather than diverting the funding to third-party entities. Others strongly supported the business models of these organizations.

We have indicated elsewhere that a system-wide review panel such as ours is not well-suited to examine these and other organizations subject to third-party agreements. We recommended instead in Chapter 4 that a new oversight body, NACRI, be created to provide expert advice and guidance on when a new entity might reasonably be supported by such an agreement. Here we make the case for enlisting NACRI in determining not just the desirability of initiating a new entity, but also whether contribution agreements should continue and, if so, on what terms.

The preceding sketches of three diverse organizations subject to contribution agreements help illustrate the rationale for this proposal. To underscore the challenges of adjudication, we elaborate briefly. Submissions highlighted that funding from Genome Canada has enabled fundamental discoveries to be made and important knowledge to be disseminated to the Canadian and international research communities. However, other experts suggested a bifurcation with CIHR or NSERC funding research-intensive development of novel technologies, while Genome Canada would focus on application (e.g., large-scale whole genome studies) and commercialization of existing technologies. From the Panel’s standpoint, these observations underscore the subtleties of determining where and how Genome Canada’s mandate overlaps and departs from that of CIHR and NSERC as well as CFI. Added to the complexity of any assessment is Genome Canada’s meaningful role in providing large-scale infrastructure grants and its commercialization program. Mitacs, even more than Genome Canada, bridges beyond academe to the private and non-profit sectors, again highlighting the advantage of having any review overseen by a body with representatives from both spheres. Finally, as did the other two entities, Brain Canada won plaudits, but some interchanges saw discussants ask when and whether it might be more efficient to flow this type of funding on a programmatic basis through CIHR.

We emphasize that the Panel’s intent here is neither to signal agreement nor disagreement with any of these submissions or discussions. We simply wish to highlight that decisions about ongoing funding will involve expert judgments informed by deep expertise in the relevant research areas and, in two of these examples, an ability to bridge from research to innovation and from extramural independent research to the private and non-profit sectors. Under current arrangements, management consulting firms and public servants drive the review and decision-making processes. Our position is that oversight by NACRI and stronger reliance on advice from content experts would be prudent given the sums involved and the nature of the issues. (pp. 102-4 print; pp. 136-8 PDF)

I wasn’t able to find anything other than this about major science initiatives (MSIs),

Big Science facilities, such as MSIs, have had particular challenges in securing ongoing stable operating support. Such facilities often have national or international missions. We termed them “major research facilities” (MRFs) xi in Chapter 4, and proposed an improved oversight mechanism that would provide lifecycle stewardship of these national science resources, starting with the decision to build them in the first instance. (p. 132 print; p. 166 PDF)

So, an MSI is an MRF? (head shaking) Why two terms for the same thing? And, how does the newly announced Pan Canadian Artificial Intelligence Strategy fit into the grand scheme of things?

The last ‘special case’ I’m featuring is the ‘Programme for Research Chairs for Excellent Scholars and Scientists’. Here’s what the report had to say about the state of affairs,

The major sources of federal funding for researcher salary support are the CRC [Canada Research Chair]and CERC [Canada Excellence Reseach Chair] programs. While some salary support is provided through council-specific programs, these investments have been declining over time. The Panel supports program simplification but, as noted in Chapter 5, we are concerned about the gaps created by the elimination of these personnel awards. While we focus here on the CRC and CERC programs because of their size, profile, and impact, our recommendations will reflect these concerns.

The CRC program was launched in 2000 and remains the Government of Canada’s flagship initiative to keep Canada among the world’s leading countries in higher education R&D. The program has created 2,000 research professorships across Canada with the stated aim “to attract and retain some of the world’s most accomplished and promising minds”5 as part of an effort to curtail the potential academic brain drain to the U.S. and elsewhere. The program is a tri-council initiative with most Chairs allocated to eligible institutions based on the national proportion of total research grant funding they receive from the three granting councils. The vast majority of Chairs are distributed based on area of research, of which 45 per cent align with NSERC, 35 per cent with CIHR, and 20 per cent with SSHRC; an additional special allocation of 120 Chairs can be used in the area of research chosen by the universities receiving the Chairs. There are two types of Chairs: Tier 1 Chairs are intended for outstanding researchers who are recognized as world leaders in their fields and are renewable; Tier 2 Chairs are targeted at exceptional emerging researchers with the potential to become leaders in their field and can be renewed once. Awards are paid directly to the universities and are valued at $200,000 annually for seven years (Tier 1) or $100,000 annually for five years (Tier 2). The program notes that Tier 2 Chairs are not meant to be a feeder group for Tier 1 Chairs; rather, universities are expected to develop a succession plan for their Tier 2 Chairs.

The CERC program was established in 2008 with the expressed aim of “support[ing] Canadian universities in their efforts to build on Canada’s growing reputation as a global leader in research and innovation.”6 The program aims to award world-renowned researchers and their teams with up to $10 million over seven years to establish ambitious research programs at Canadian universities, making these awards among the most prestigious and generous available internationally. There are currently 27 CERCs with funding available to support up to 30 Chairs, which are awarded in the priority areas established by the federal government. The awards, which are not renewable, require 1:1 matching funds from the host institution, and all degree-granting institutions that receive tri-council funding are eligible to compete. Both the CERC and CRC programs are open to Canadians and foreign citizens. However, until the most recent round, the CERCs have been constrained to the government’s STEM-related priorities; this has limited their availability to scholars and scientists from SSHRC-related disciplines. As well, even though Canadian-based researchers are eligible for CERC awards, the practice has clearly been to use them for international recruitment with every award to date going to researchers from abroad.

Similar to research training support, the funding for salary support to researchers and scholars is a significant proportion of total federal research investments, but relatively small with respect to the research ecosystem as a whole. There are more than 45,000 professors and teaching staff at Canada’s universities7 and a very small fraction hold these awards. Nevertheless, the programs can support research excellence by repatriating top Canadian talent from abroad and by recruiting and retaining top international talent in Canada.

The programs can also lead by example in promoting equity and diversity in the research enterprise. Unfortunately, both the CRC and CERC programs suffer from serious challenges regarding equity and diversity, as described in Chapter 5. Both programs have been criticized in particular for under-recruitment of women.

While the CERC program has recruited exclusively from outside Canada, the CRC program has shown declining performance in that regard. A 2016 evaluation of the CRC program8  observed that a rising number of chairholders were held by nominees who originated from within the host institution (57.5 per cent), and another 14.4 per cent had been recruited from other Canadian institutions. The Panel acknowledges that some of these awards may be important to retaining Canadian talent. However, we were also advised in our consultations that CRCs are being used with some frequency to offset salaries as part of regular faculty complement planning.

The evaluation further found that 28.1 per cent of current chairholders had been recruited from abroad, a decline from 32 per cent in the 2010 evaluation. That decline appears set to continue. The evaluation reported that “foreign nominees accounted, on average, for 13 per cent and 15 per cent respectively of new Tier 1 and Tier 2 nominees over the five-year period 2010 to 2014”, terming it a “large decrease” from 2005 to 2009 when the averages respectively were 32 per cent and 31 per cent. As well, between 2010-11 and 2014-15, the attrition rate for chairholders recruited from abroad was 75 per cent higher than for Canadian chairholders, indicating that the program is also falling short in its ability to retain international talent.9

One important factor here appears to be the value of the CRC awards. While they were generous in 2000, their value has remained unchanged for some 17 years, making it increasingly difficult to offer the level of support that world-leading research professors require. The diminishing real value of the awards also means that Chair positions are becoming less distinguishable from regular faculty positions, threatening the program’s relevance and effectiveness. To rejuvenate this program and make it relevant for recruitment and retention of top talent, it seems logical to take two steps:

• ask the granting councils and the Chairs Secretariat to work with universities in developing a plan to restore the effectiveness of these awards; and

• once that plan is approved, increase the award values by 35 per cent, thereby restoring the awards to their original value and making them internationally competitive once again.

In addition, the Panel observes that the original goal was for the program to fund 2,000 Chairs. Due to turnover and delays in filling Chair positions, approximately 10 to 15 per cent of them are unoccupied at any one time.i As a result, the program budget was reduced by $35 million in 2012. However, the occupancy rate has continued to decline since then, with an all-time low of only 1,612 Chair positions (80.6 per cent) filled as of December 2016. The Panel is dismayed by this inefficiency, especially at a time when Tier 2 Chairs remain one of the only external sources of salary support for ECRs [early career researchers]—a group that represents the future of Canadian research and scholarship. (pp. 142-4 print; pp. 176-8 PDF)

I think what you can see as a partial subtext in this report and which I’m attempting to highlight here in ‘special cases’ is a balancing act between supporting a broad range of research inquiries and focusing or pouring huge sums of money into ‘important’ research inquiries for high impact outcomes.

Final comments

There are many things to commend this report including the writing style. The notion that more coordination is needed amongst the various granting agencies, that greater recognition (i.e,, encouragement and funding opportunities) should be given to boundary-crossing research, and that we need to do more interprovincial collaboration is welcome. And yes, they want more money too. (That request is perfectly predictable. When was the last time a report suggested less funding?) Perhaps more tellingly, the request for money is buttressed with a plea to make it partisan-proof. In short, that funding doesn’t keep changing with the political tides.

One area that was not specifically mentioned, except when discussing prizes, was mathematics. I found that a bit surprising given how important the field of mathematics is to  to virtually all the ‘sciences’. A 2013 report, Spotlight on Science, suggests there’s a problem(as noted my Oct. 9, 2013 posting about that report,  (I also mention Canada’s PISA scores [Programme for International Student Assessment] by the OECD [Organization for Economic Cooperation and Development], which consistently show Canadian students at the age of 15 [grade 10] do well) ,

… it appears that we have high drop out rates in the sciences and maths, from an Oct. 8, 2013 news item on the CBC (Canadian Broadcasting Corporation) website,

… Canadians are paying a heavy price for the fact that less than 50 per cent of Canadian high school students graduate with senior courses in science, technology, engineering and math (STEM) at a time when 70 per cent of Canada’s top jobs require an education in those fields, said report released by the science education advocacy group Let’s Talk Science and the pharmaceutical company Amgen Canada.

Spotlight on Science Learning 2013 compiles publicly available information about individual and societal costs of students dropping out STEM courses early.

Even though most provinces only require math and science courses until Grade 10, the report [Spotlight on Science published by Let’s Talk Science and pharmaceutical company Amgen Canada) found students without Grade 12 math could expect to be excluded from 40 to 75 per cent of programs at Canadian universities, and students without Grade 11 could expect to be excluded from half of community college programs. [emphasis mine]

While I realize that education wasn’t the panel’s mandate they do reference the topic  elsewhere and while secondary education is a provincial responsibility there is a direct relationship between it and postsecondary education.

On the lack of imagination front, there was some mention of our aging population but not much planning or discussion about integrating older researchers into the grand scheme of things. It’s all very well to talk about the aging population but shouldn’t we start introducing these ideas into more of our discussions on such topics as research rather than only those discussions focused on aging?

Continuing on with the lack of  imagination and lack of forethought, I was not able to find any mention of independent scholars. The assumption, as always, is that one is affiliated with an institution. Given the ways in which our work world is changing with fewer jobs at the institutional level, it seems the panel was not focused on important and fra reaching trends. Also, there was no mention of technologies, such as artificial intelligence, that could affect basic research. One other thing from my wish list, which didn’t get mentioned, art/science or SciArt. Although that really would have been reaching.

Weirdly, one of the topics the panel did note, the pitiifull lack of interprovincial scientific collaboration, was completely ignored when it came time for recommendations.

Should you spot any errors in this commentary, please do drop me a comment.

Other responses to the report:

Nassif Ghoussoub (Piece of Mind blog; he’s a professor mathematics at the University of British Columbia; he attended one of the roundtable discussions held by the panel). As you might expect, he focuses on the money end of things in his May 1, 2017 posting.

You can find a series of essays about the report here under the title Response to Naylor Panel Report ** on the Canadian Science Policy Centre website.

There’s also this May 31, 2017 opinion piece by Jamie Cassels for The Vancouver Sun exhorting us to go forth collaborate internationally, presumably with added funding for the University of Victoria of which Cassels is the president and vice-chancellor. He seems not to have noticed that Canadian do much more poorly with interprovincial collaboration.

*ETA June 21, 2017: I’ve just stumbled across Ivan Semeniuk’s April 10, 2017 analysis (Globe and Mail newspaper) of the report. It’s substantive and well worth checking out.*

Again, here’s a link to the other parts:

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report) Commentaries

Part 1

Part 2

*’up’ added on June 8, 2017 at 15:10 hours PDT.

**’Science Funding Review Panel Repor’t was changed to ‘Responses to Naylor Panel Report’ on June 22, 2017.

Canada and its review of fundamental science

Big thanks to David Bruggeman’s June 14, 2016 post (on his Pasco Phronesis blog) for news of Canada’s Fundamental Science Review, which was launched on June 13, 2016 (Note: Links have been removed),

The panel’s mandate focuses on support for fundamental research, research facilities, and platform technologies.  This will include the three granting councils as well as other research organisations such as the Canada Foundation for Innovation. But it does not preclude the panel from considering and providing advice and recommendations on research matters outside of the mandate.  The plan is to make the panel’s work and recommendations readily accessible to the public, either online or through any report or reports the panel produces.  The panel’s recommendations to Minister Duncan are non-binding. …

As Ivan Semeniuk notes at The Globe and Mail [Canadian ‘national’ newspaper], the recent Nurse Review in the U.K., which led to the notable changes underway in the organization of that country’s research councils, seems comparable to this effort.  But I think it worth noting the differences in the research systems of the two countries, and the different political pressures in play.  It is not at all obvious to this writer that the Canadian review would necessarily lead to similar recommendations for a streamlining and reorganization of the Canadian research councils.

Longtime observers of the Canadian science funding scene may recall an earlier review held under the auspices of the Steven Harper Conservative government known as the ‘Review of Federal Support to R&D’. In fact it was focused on streamlining government funding for innovation and commercialization of science. The result was the 2011 report, ‘Innovation Canada: A Call to Action’, known popularly as the ‘Jenkins report’ after the panel chair, Tom Jenkins. (More about the report and responses to it can be found in my Oct. 21, 2011 post).

It’s nice to see that fundamental science is being given its turn for attention.

A June 13, 2016 Innovation, Science and Economic Development Canada news release provides more detail about the review and the panel guiding the review,

The Government of Canada understands the role of science in maintaining a thriving, clean economy and in providing the evidence for sound policy decisions. To deliver on this role however, federal programs that support Canada’s research efforts must be aligned in such a way as to ensure they are strategic, effective and focused on meeting the needs of scientists first.

That is why the Honourable Kirsty Duncan, Minister of Science, today launched an independent review of federal funding for fundamental science. The review will assess the program machinery that is currently in place to support science and scientists in Canada. The scope of the review includes the three granting councils [Social Sciences and Humanities Research Council {SSHRC}, Natural Sciences and Engineering Research Council {NSERC}, Canadian Institutes of Health Research {CIHR}] along with certain federally funded organizations such as the Canada Foundation for Innovation [CFI].

The review will be led by an independent panel of distinguished research leaders and innovators including Dr. David Naylor, former president of the University of Toronto and chair of the panel. Other panelists include:

  • Dr. Robert Birgeneau, former chancellor, University of California, Berkeley
  • Dr. Martha Crago, Vice-President, Research, Dalhousie University
  • Mike Lazaridis, co-founder, Quantum Valley Investments
  • Dr. Claudia Malacrida, Associate Vice-President, Research, University of Lethbridge
  • Dr. Art McDonald, former director of the Sudbury Neutrino Laboratory, Nobel Laureate
  • Dr. Martha Piper, interim president, University of British Columbia
  • Dr. Rémi Quirion, Chief Scientist, Quebec
  • Dr. Anne Wilson, Canadian Institute for Advanced Research Successful Societies Fellow and professor of psychology, Wilfrid Laurier University

The panel will spend the next six months seeking input from the research community and Canadians on how to optimize support for fundamental science in Canada. The panel will also survey international best practices for funding science and examine whether emerging researchers face barriers that prevent them from achieving career goals. It will look at what must be done to address these barriers and what more can be done to encourage Canada’s scientists to take on bold new research challenges. In addition to collecting input from the research community, the panel will also invite Canadians to participate in the review [emphasis mine] through an online consultation.

Ivan Semeniuk in his June 13, 2016 article for The Globe and Mail provides some interesting commentary about the possible outcomes of this review,

Depending on how its recommendations are taken on board, the panel could trigger anything from minor tweaks to a major rebuild of Ottawa’s science-funding apparatus, which this year is expected to funnel more than $3-billion to Canadian researchers and their labs.

Asked what she most wanted the panel to address, Ms. Duncan cited, as an example, the plight of younger researchers who, in many cases, must wait until they are in their 40s to get federal support.

Another is the risk of losing the benefits of previous investments when funding rules become restrictive, such as a 14-year limit on how long the government can support one of its existing networks of centres of excellence, or the dependence of research projects that are in the national interest on funding streams that require support from provincial governments or private sources.

The current system for proposing and reviewing research grants has been criticized as cumbersome and fraught with biases that mean the best science is not always supported.

In a paper published on Friday in the research journal PLOS One, Trent University biologist Dennis Murray and colleagues combed through 13,526 grant proposals to the Natural Sciences and Engineering Research Council between 2011 and 2014 and found significant evidence that researchers at smaller universities have consistently lower success rates.

Dr. Murray advocates for a more quantitative and impartial system of review to keep such biases at bay.

“There are too many opportunities for human impressions — conscious or unconscious — to make their way into the current evaluation process,” Dr. Murray said.

More broadly, researchers say the time is right for a look at a system that has grown convoluted and less suited to a world in which science is increasingly cross-disciplinary, and international research collaborations are more important.

If you have time, I encourage you to take a look at Semeniuk’s entire article as for the paper he mentions, here’s a link to and a citation for it,

Bias in Research Grant Evaluation Has Dire Consequences for Small Universities by Dennis L. Murray, Douglas Morris, Claude Lavoie, Peter R. Leavitt, Hugh MacIsaac,  Michael E. J. Masson, & Marc-Andre Villard. PLOS http://dx.doi.org/10.1371/journal.pone.0155876  Published: June 3, 2016

This paper is open access.

Getting back to the review and more specifically, the panel, it’s good to see that four of the nine participants are women but other than that there doesn’t seem to be much diversity, i.e.,the majority (five) spring from the Ontario/Québec nexus of power and all the Canadians are from the southern part of country. Back to diversity, there is one business man, Mike Laziridis known primarily as the founder of Research in Motion (RIM or more popularly as the Blackberry company) making the panel not a wholly ivory tower affair. Still, I hope one day these panels will have members from the Canadian North and international members who come from somewhere other than the US, Great Britain, and/or if they’re having a particularly wild day, Germany. Here are some candidate countries for other places to look for panel members: Japan, Israel, China, South Korea, and India. Other possibilities include one of the South American countries, African countries, and/or the Middle Eastern countries.

Take the continent of Africa for example, where many countries seem to have successfully tackled one of the issues as we face. Specifically, the problem of encouraging young researchers. James Wilsdon notes some success in his April 9, 2016 post about Africa and science advice for the Guardian science blogs (Note: Links have been removed),

… some of the brightest talents and most exciting advances in African science were on display at the Next Einstein Forum. This landmark meeting, initiated by the African Institute of Mathematical Sciences, and held in Senegal, brought together almost 1000 researchers, entrepreneurs, businesses and policymakers from across Africa to celebrate and support the continent’s most promising early-career researchers.

A new cadre of fifteen Next Einstein Fellows and fifty-four ambassadors was announced, and the forum ended with an upbeat declaration of commitment to Africa’s role in world-leading, locally-relevant science. …

… UNESCO’s latest global audit of science, published at the end of 2015, concludes that African science is firmly on the rise. The number of journal articles published on the continent rose by sixty per cent from 2008 to 2014. Research investment rose from $12.9 billion in 2007 to $19.9 billion (US dollars) in 2013. Over the same period, R&D expenditure as a percentage of GDP nudged upwards from 0.36 per cent to 0.45 per cent, and the population of active researchers expanded from 150,000 to 190,000.

If you have the time, do read Wilsdon’s piece which covers some of the more difficult aspects facing the science communities in Africa and more.

In any event, it’s a bit late to bemoan the panel’s makeup but hopefully the government will take note for the future as I’m planning to include some of my critique in my comments to the panel in answer to their request for public comments.

You can find out more about Canada’s Fundamental Science Review here and you can easily participate here and/or go here to subscribe for updates.

Queen’s University (Canada) opens Kingston Nano-Fabrication Lab (KNFL)

First, there’s the opening (from an April 24, 2015 Queen’s University news release; Note: A link has been removed),

Queen’s University has secured its place at the forefront of transforming innovative research with the opening of the Kingston Nano-Fabrication Laboratory (KNFL).

The laboratory, located at Innovation Park, represents a milestone in the 30-year collaboration between Queen’s and CMC Microsystems for advancing Canadian strength in micro-nano innovation.

Some interesting details about the deal and the proposed uses for KNFL can be found in an April 24, 2015 story by Colleen Seto for Canada Foundation for Innovation (CFI),

… a brand-new, 3,000-square-foot, $5 million research facility [KNFL] located at the Queen’s University Innovation Park. The lab includes $2.5 million in new CFI-funded custom equipment for fabricating and prototyping new nano-scale inventions to get them to market quicker.

“We’re making devices, films, coatings, and materials, and examining their properties at the nanoscale,” says Ian McWalter, President and CEO of CMC Microsystems, which manages the operations of KNFL. “This fundamental materials research spills over into experiments of great use to industry, which then looks at how to commercialize he research results.”

The Queen’s University news release describes the longstanding relationship between the company managing the KNFL and the university,

“This facility is the latest manifestation of a long and productive relationship between Queen’s and CMC Microsystems,” says Ian McWalter, president and CEO of CMC. “For more than three decades, this partnership has enabled research and advanced training activities nationwide that would not have otherwise occurred. The KNFL is a significant enhancement, and we look forward to exploring the expanded opportunities that it offers us for building Canadian strength in micro-nano research and innovation.”

The CFI story provides more specifics about the potential workings of the facility,

Take, for example, the possibilities presented by KNFL’s laser micromachining system. “This new tool could be used to engrave channels into a piece of glass or polymer to produce a microfluidic device,” says Andrew Fung, Client Technology Advisor for Microsystems and Nanotechnology at CMC. Microfluidic devices take advantage of the behaviour of fluids at a very small scale to create things like “lab-on-a-chip” technologies that can be used to cheaply and quickly diagnose diseases in developing countries, among many other things. “Microfluidics grew out of silicon-based fabrication, which costs a lot of money,” explains Fung. “These other materials are lower cost, and can be single use, consumable, and disposable for a medical device.”

Much of KNFL’s new equipment was selected to enable rapid prototyping of new nanotechnologies. “Prototypes can be ready within hours or a day, instead of days or weeks. It shortens the whole innovation process so researchers can design, make, test, and get the information they need much faster,” says Fung.

The CFI story also contextualizes this project by noting that it’s part of a larger initiative,

The KNFL is also part of Embedded Systems Canada (emSYSCAN), a $50-million, five-year project aimed at shortening the microsystems development cycle. It involves more than 350 university researchers at 37 institutions across Canada’s National Design Network (NDN), which enables multidisciplinary research and collaboration through shared technologies and expertise.

The KNFL’s open-access model is aimed specifically at supporting the NDN. “The idea is to make [expertise and tools] more available to non-experts and to overcome barriers such as lab training to access this equipment,” says McWalter. “Through the service aspect of our lab, you wouldn’t necessarily twiddle the knobs yourself, but you would contract the lab to do things for you.” This provides vital learning opportunities for students while giving researchers a more efficient means to an end — accessing the equipment they need without having to invest the time and effort to learn how to use it.

Congratulations to the folks at Queen’s University!

State-of-the-art biotech and nanophotonics equipment at Québec’s Institut national de la recherche scientifique (INRS)

Canada Foundation for Innovation (a federal government funding agency) has awarded two infrastructure grants to Québec’s Institut national de la recherche scientifique (INRS) or more specifically their Énergie Matériaux Télécommunications Research Centreaccording to an April 18, 2014 news item on Azonano,

Professor Marc André Gauthier and Professor Luca Razzari of the Énergie Matériaux Télécommunications Research Centre have each been awarded large grants from the John R. Evans Leaders Fund of the Canada Foundation for Innovation (CFI) for the acquisition of state-of-the-art biotech and nanophotonics equipment.

To this funding will be added matching grants from the Ministère de l’Enseignement supérieur, de la Recherche, de la Science et de la Technologie (MESRST). These new laboratories will help us develop new approaches for improving health and information technologies, train the next generation of highly qualified high-tech workers, and transfer technology and expertise to local startups.

An April 17, 2014 INRS news release by Gisèle Bolduc, which originated the news item (Pour ceux qui préfèrent l’actualité en français) , provides more details,

Bio-hybrid materials

Professor Gauthier’snew Laboratory of Bio-Hybrid Materials (LBM) will enable him to tackle the numerous challenges of designing these functional materials and make it possible for the biomedical and biotech sectors to take full advantage of their new and unique properties. Professor Gauthier and his team will work on developing new bio organic reactions involving synthetic and natural molecules and improving those that already exist. They will examine the architecture of protein-polymer grafts and develop methods for adjusting the structure and function of bio-hybrid materials in order to evaluate their therapeutic potential.

Plasmonic nanostructures and nonlinear optics

Professor Luca Razzari will use his Laboratory of Nanostructure-Assisted Spectroscopy and Nonlinear Optics (NASNO Lab) to document the properties of plasmonic nanostructures, improve nanospectroscopies and explore new photonic nanodevices. He will also develop new biosensors able to identify very small numbers of biomarkers. This may have an important impact in the early diagnosis of several diseases such as cancer and life-threatening infectious diseases.Besides this, he will investigate a new generation of nanoplasmonic devices for information and communications technology applications.

Congratulations!

A couple of nanoscientists and the Canada Research Chair (CRC) programme

The announcements about Canada’s latest round of Canada Research Chairs were made on Friday, Mar. 15, 2013 (that’s when I received a news release from Simon Fraser University [Vancouver, Canada] about their bonanza). The Canada Research Chairs programme has issued a Mar. 15, 2012 news release but it has no details as to which chairs have been awarded, so I can only offer information from the two agencies touting their nanotechnology chairs.

Simon Fraser University (SFU) had this to say about its latest financial windfall (from the SFU Mar. 15, 2013 news release),

Four Simon Fraser University researchers will gain nearly $2.9 million to continue their research fellowships as Canada Research Chairs in areas as diverse as climate change, marine conservation, children’s health, and nanotechnology.

The funds are part of a $90.6 million injection by the federal government into the Canada Research Chair program, supporting 120 newly awarded and renewed chairs across the country.

Here’s the information about the nanotechnology/materials science chair (from the SFU news release),

Chemistry professor Neil Branda of Chemistry has begun his second seven-year term as SFU’s Tier 1 Canada Research Chair in Materials Science.  Operating at the crossroads of organic chemistry, materials science, and nanotechnology, his research program involves the design and synthesis of photo-responsive compounds and their integration with nanosystems.

Branda, a recognized leader in materials science and co-founder of SFU’s 4D LABS, heads the Prometheus Project, a collaboration of BC’s research universities that will bring global attention to B.C.’s rich capabilities in this industry-relevant field.

I highlighted some information about Branda and the Canada Foundation for Innovation, which had just announced its funding for the Prometheus Project, in a Jan. 15, 2013 posting,

The Federal Government of Canada in the guise of the Canada Foundation for Innovation has just awarded $7.7M to Simon Fraser University (SFU) and its partners for a global innovation hub. From the Jan. 15, 2013 Canada Foundation for Innovation news release,

British Columbia’s research-intensive universities are coming together to create a global hub for materials science and engineering. Simon Fraser University, the University of Victoria, the University of British Columbia and the British Columbia Institute of Technology have received $7.7 million in funding from the Canada Foundation of Innovation to create the Prometheus Project — a research hub for materials science and engineering innovation and commercialization.

“Our goal with the Prometheus Project is to turn our world-class research capacity into jobs and growth for the people of British Columbia,” said Neil Branda, Canada Research Chair in Materials Science at Simon Fraser University and leader of the Prometheus Project. [emphasis added for Mar. 18, 2013 posting]

According to the Mar. 16, 2013 news item on Azonano there was also an announcement in the province of Alberta,

The Honourable Laurie Hawn, Member of Parliament for Edmonton Centre, today announced an investment of $5.8 million to support eight Canada Research Chairs in Alberta as part of the national announcement made by the Honourable Gary Goodyear, Minister of State (Science and Technology).

Today’s event featured Dr. Tian Tang, Canada Research Chair in Nano-biomolecular Hybrid Materials at the University of Alberta. Dr. Tang and her team are working to better understand how nano-sized organic and inorganic materials interact. Their research will help future scientists and innovators develop nano-sized machines that could be useful in electronics, computing, manufacturing and health care. This research will help establish Canada’s leadership in this field, which is expected to be one of the most commercially important and fastest-growing areas of health care and engineering in the 21st century.

Congratulations to all the researchers!

Sci comm, Canada, and the Faster, Pussycat! Kill! Kill! network of Canadian science blog(ger)s

If a hashtag (ou mot-dièse en français) is a way to judge these things, there’s an upswing of interest in Canadian science communication. The hashtag in question is #cancomm (on Twitter) and seems to have developed a life beyond its original designation as a Twitter stream devoted to one of the sessions at the ScienceOnline2013 conference held Jan. 30 – Feb. 2, 2013 in North Carolina, USA.

Before mentioning anything about the latest developments (I sent some interview questions to both of the presenters), here’s more about the ScienceOnline 2013 session titled Communicating science where there is no science communication presented by Marie-Claire Shanahan and Colin Schultz who focused on the situation in Canada,

Scientists, journalists, and communicators working outside of the United States and the UK face fundamentally different problems from those living within well-served media landscapes. For example: Canada has few science magazines, a couple television shows, and a handful of radio programmes aimed at a general science audience (with the exception of the French-speaking Quebec, which has a dynamic science writing community). Government funded research grants do not require outreach or education. [emphasis mine] And, government scientists have been all but barred from talking to journalists. In Canada and other countries with sparse science communication infrastructures, the dominant issues revolve not around journalists vs bloggers, or scientists vs press releases vs the media, but instead focus on what can be done to make science communication exist at all, in any form. This session will explore how scientists, educators, and media people can promote scientific discussions and scientific interest in regions that lack established venues.

A number of salient (and I believe them to be indisputable) points are made. I did highlight one statement which is arguable. There is one funding agency (granted, only one) which includes a requirement for outreach/communication and that is the Canada Foundation for Innovation (CFI). From Section 8 of the CFI’s Policy and Program document (PDF) dated March 2012,

As an independent corporation created by the Government of Canada, the CFI places paramount importance on demonstrating to Canadians the impacts and outcomes of its investments. And as recipients of CFI funding, institutions have an essential role to play in highlighting the impacts, outcomes and benefits of research, through communications activities such as:

• news releases, news conferences and other media relations initiatives;

• print and online publications;

• social media;

• special events (groundbreakings, openings, milestone celebrations, conferences and other public outreach activities);

• presentations;

• correspondence;

• advertising.

In the context of these activities, the CFI also requests that institutions acknowledge the financial support of the CFI. (p. 81)

At any rate, I did send off some questions in hopes of an interview with both presenters but, as sometimes happens, Marie-Claire Shanahan has not replied and, more uniquely,  Colin Schultz has decided to publish my questions and his answers on his own blog.  My policy with the interviews I conduct is to publish the replies along with the questions in their entirety changing only the typos. I don’t offer any observations of my own after the fact. Since Colin Schultz has published the interview himself, I will treat it as I do anything else I find on web. I do not copy an entire piece but will excerpt the bits I find interesting and comment at will.

According to the ‘secret source’ who attended your presentation, you and Marie-Claire were very harsh in your assessments of the science communication efforts and environment in Canada. Given that most of my readers won’t have attended the presentation, could you summarize the presentation in a few bullet points and note where you agree and disagree with your co-presenter?

… Science Online pulls together brilliant, creative, hard-working and entrepreneurial problem solvers, communicators with a passion for science and a vigilante spirit. Many of these people, however, also have basically no idea what is going on in Canada in terms of the political atmosphere, the size of the mainstream press, or the scope of the science communication community. [emphasis mine] One of the goals I had in mind when putting together my short introduction for the session was that I wanted to tap into these clever minds so that we could all put our heads together and come up with projects that will work within the Canadian cultural context. [emphasis mine]

The Shanahan/Schultz presentation was 60 minutes long.  So, these people got to know Canada and the Canadian science communication scene well enough in 60 minutes to suggest projects that work within the Canadian cultural context. Interesting.

Here’s more from question 1 (Note: I have removed links),

I opened the session with numbers: We have one mainstream science magazine, two TV shows, and one radio show. A 1998 study found that we had 18 full time science journalists at daily newspapers, and I mused that this number probably went down as the media industry crashed and companies cut their staff.

With no official science blogger database that I know of, I pulled from your (Maryse’s) own annual counts (2010, 2011, 2012) and the self-selected bloggers pulled together by the Canadian Science Writers’ Association to estimate that there are likely a few dozen science bloggers in the country. [emphasis mine] Discussions in the room pointed out that there are probably more than listed in those two places, but the order of magnitude on the guess is probably close enough.

I believe my last annual count (2012 roundup) listed approximately 40 – 50 more or less active, including English and French language, Canadian Science blogs/bloggers. (A colleague recently [Feb. 15, 2013] produced a spreadsheet list of approximately 70 active blogs/bloggers.) More from Schultz on the first question,

From the numbers I moved into my second main point, asking: “Why does any of this matter?” Scientific knowledge is borderless, so does it really matter if we hear about Canadian science?

To answer this I suggested that there is a split: for people learning about science, for keeping up with all the cool developments that are taking shape around the world, then no, it doesn’t really matter. Canadian, American, English, Australian—wherever your news comes from doesn’t really make much a difference.

But, there is the other side of it. There are serious scientific issues in Canadian life—the tar sands, oceans management, fisheries research, the climate of the Arctic—that will only really be addressed by Canadians, and outside of the larger issues of climate change or biodiversity, only really affect Canadians. Without established venues to discuss and report and debate science, without an established culture of science communication, there won’t necessarily be the conversation that we need on these and other issues.

I noted that when people aren’t aware of the work being done by Canadian scientists or Canadian federal agencies that it could become easier for those projects to slide away, a case that came to the fore recently with the cutting of federal scientists, the potential closing of the Experimental Lakes, or the issue of muzzling.

Then, there were the 2nd, 3rd, and 4th questions,

Were you trying to be harsh in your assessment? I read the presentation description which didn’t have a single positive comment about efforts in English Canada; did that hold true for the presentation or did you leaven it with some positive comments (and what were those positive comments)? Note: A link has been removed.

There is a lot of good science communication going on in Canada. Personally, I think that Daily Planet is a treasure, and following the session I had people asking how they could see it from abroad. Marie-Claire, and some audience members, raised examples of informal or non-mainstream media projects that are doing great work on science communication and science outreach.

Would it surprise you to know that about the same time you gave your presentation a group (with no prior knowledge of said presentation) had formed to create a Canadian science blogging network? Full disclosure: I am a member of this group.

I heard whispers of this in the hallways at the conference, and think it’s a great idea. Building a blogging network will help draw people together, and help them find one another. I think that we have a lot of really serious issues to tackle, but this is a great place to start.

Purely for fun, I have three names for a national network. (These names are not from the group.) Which one would you join, if you one had one choice?

(a) Canuckian science blog(ger) network?
(b) Canadian science blog(ger) network?
(c) Faster, Pussycat! Kill! Kill! Canadian science blog(ger) network?

The last one, definitely.

You can find the entire set of responses at Colin Schultz’s blog. I wish him good luck as he breathes some life back into it. (His last posting prior to this ‘interview’ was on July 13, 2012, and the posting before that was dated Feb. 8, 2012.)

Note: I did correct two of my own interview typos in the words ‘assessment’ and ‘with’.

There are in fact two groups (that I know of) who have talked about putting together a Canadian science blog(ger) network. There was the group forming at the ScienceOnline 2013 conference and there was another group forming as a consequence of a suggestion in my 2012 roundup. The two groups appear to be coalescing but it’s all very loose at this point. Who knows? There may be other groups who just haven’t made themselves known as yet.

What can be said for certain is this,  Mike Spear at Genome Alberta has created the CanComm.org website for Canadian science communicators, aka, CanComm – Communication with a Science Flavour and a Canadian Twist. Sarah Boon, one of the organizers of our hoped for network, has written a Feb. 23, 2013 post on her Watershed Moments blog that provides pointed and thoughtful insight into many of the current issues on the Canadian science scene and the Canadian science communication scene and includes this (Note: Links have been removed),

It’s not that we don’t have an interested and involved public and the science communicators to engage them. It’s more that we don’t have the infrastructure to link communicators together like the Americans do with the Science Online meeting in Raleigh or the AAAS Meeting in Boston, or blog networks like PLoS Blogs or the Discover and SciAm networks.

To that end, groups like Genome Alberta, the Canadian Science Writers Association (CSWA), the Science Media Centre of Canada (SMCC), and Canadian Science Publishing (CSP) are working with individuals such as myself, @frogheart, @8CrayonScience, @raymondsbrain and others to build a Canadian science communication and (ultimately) blog network. If you’re interested in joining, you can register at cancomm.org.

Full disclosure: One of my pieces got a shoutout in another part of Sarah’s posting and I’m chuffed. Regardless, I still would have described her posting as pointed and thoughtful and I notice I’m not alone as per the #cancomm twitter feed.

For anyone interested in the latest regarding the French language version of hashtag, there’s a Jan. 24, 2013 article in The Connexion; France’s English-language newspaper,

THE French government has caused amusement on the internet by insisting the proper term for “hashtag” in French should be mot-dièse.
I look forward to seeing you all at cancomm.org in any language we can use to communicate.

Simon Fraser University completes a successful mating dance while TRIUMF (Canada’s national laboratory for particle and nuclear physics) gets its groove on

The Federal Government of Canada in the guise of the Canada Foundation for Innovation has just awarded $7.7M to Simon Fraser University (SFU) and its partners for a global innovation hub. From the Jan. 15, 2013 Canada Foundation for Innovation news release,

British Columbia’s research-intensive universities are coming together to create a global hub for materials science and engineering. Simon Fraser University, the University of Victoria, the University of British Columbia and the British Columbia Institute of Technology have received $7.7 million in funding from the Canada Foundation of Innovation to create the Prometheus Project — a research hub for materials science and engineering innovation and commercialization.

“Our goal with the Prometheus Project is to turn our world-class research capacity into jobs and growth for the people of British Columbia,” said Neil Branda, Canada Research Chair in Materials Science at Simon Fraser University and leader of the Prometheus Project. “We know that materials science is changing the way we create energy and fight disease. We think it can also help B.C.’s economy evolve.”

This project builds on a strong collective legacy of collaborating with industry. Researchers involved in the Prometheus Project have created 13 spin-off companies, filed 67 patents and have generated 243 new processes and products. [emphasis mine] Branda himself has founded a company called Switch Materials that seizes the power of advanced chemistry to create smarter and more efficient window coatings.

This funding will allow members of the research team to build their capacity in fabrication, device testing and advanced manufacturing, ensuring that they have the resources and expertise they need to compete globally.

There’s a bit more information about the Prometheus project in a Jan.15, 2013 backgrounder supplied by SFU,

Led by Neil Branda, a Canada Research Chair in Materials Science and SFU chemistry professor, The Prometheus Project is destined to become a research hub for materials science and engineering innovation, and commercialization globally.

It brings together 10 principal researchers, including Branda, co-founder of SFU’s 4D LABS (a materials research facility with capabilities at the nanoscale], and 20 other scientists at SFU, University of British Columbia, the University of Victoria and the British Columbia Institute of Technology. They will create new materials science and engineering (MS&E) technology innovations, which will trigger and support sustained economic growth by creating, transforming and making obsolete entire industries.

Working with internationally recognized industrial, government, hospital and academic collaborators, scientists at the Prometheus partners’ labs, including 4D LABS, a $40 million materials science research institute, will deliver innovations in three areas. The labs will:

  • Develop new solar-industry related materials and devices, including novel organic polymers, nanoparticles, and quantum dots, which will be integrated in low cost, high efficiency solar cell devices. The goal is to create a new generation of efficient solar cells that can compete in terms of cost with non-renewable technologies, surpassing older ones in terms of miniaturization and flexibility.
  • Develop miniaturized biosensors that can be used by individuals in clinical settings or at home to allow early detection of disease and treatment monitoring. They will be integrated into flexible electronic skins, allowing health conditions to be monitored in real-time.
  • Develop spintronics (magnetic devices) and quantum computing and information devices that will enable new approaches to significantly improve encrypted communication and security in financial transactions.

“This project will allow B.C.’s four most research intensive institutes to collaborate on fundamental materials research projects with a wide range of potential commercial applications,” notes Branda. “By engaging with a large community of industry, government and NGO partners, we will move this research out of the lab and into society to solve current and future challenges in important areas such as energy, health and communications.”

The Prometheus team already has a strong network of potential end users of resulting technologies. It is based on its members’ relationships with many of more than 25 companies in BC commercializing solar, biomedical and quantum computing devices.

Researchers and industries worldwide will be able to access Prometheus’s new capabilities on an open-access basis. [emphasis mine]

There are a few things I’d like to point out (a) 13 spin-off companies? There’s no mention as to whether they were successful, i.e., created jobs or managed a life beyond government funding. (b) Patents as an indicator for innovation? As I’ve noted many, many times that’s a very problematic argument to make. (c) New processes and products? Sounds good but there are no substantiating details.  (d) Given the emphasis on commercializing discoveries and business, can I assume that open-access to Prometheus’ capabilities means that anyone willing and able to pay can have access?

In other exciting SFU news which also affects TRIUMF, an additional $1M is being awarded by the Canada Foundation for Innovation to upgrade the ATLAS Tier-1 Data Analysis Centre. From the SFU backgrounder,

Led by Mike Vetterli, a physics professor at SFU and TRIUMF, this project involves collaborating with scientists internationally to upgrade a component of a global network of always-on computing centres. Collectively, they form the Worldwide Large Hadron Collider Computing Grid (WLCG).

The Canadian scientists collaborating with Vetterli on this project are at several research-intensive universities. They include Carleton University, McGill University, University of British Columbia, University of Alberta, University of Toronto, University of Victoria, Université de Montréal, and York University, as well as TRIUMF. It’s Canada’s national lab for particle and nuclear physics research.

The grid, which has 10 Tier-1 centres internationally, is essentially a gigantic storage and processing facility for data collected from the ATLAS  experiment. The new CFI funding will enable Vetterli and his research partners to purchase equipment to upgrade the Tier-1 centre at TRIUMF in Vancouver, where the equipment will remain.

ATLAS is a multi-purpose particle detector inside a massive atom-smashing collider housed at CERN, the world’s leading laboratory for particle physics in Geneva, Switzerland.

More than 3,000 scientists internationally, including Vetterli and many others at SFU, use ATLAS to conduct experiments aimed at furthering global understanding of how the universe was physically formed and operates.

The detector’s fame for being a window into nature’s true inner workings was redoubled last year. It helped scientists, including Vetterli and others at SFU, discover a particle that has properties consistent with the Higgs boson.

Peter Higgs, a Scottish physicist, and other scientists theorized in 1964 about the existence of the long-sought-after particle that is central to the mechanism that gives subatomic particles their mass.

Scientists now need to upgrade the WLCG to accommodate the massive volume of data they’re reviewing to confirm that the newly discovered particle is the Higgs boson. If it is, it will revolutionize the way we see mass in physics.

“This project will enable Canadian scientists to continue to play a leading role in ATLAS physics analysis projects such as the Higgs boson discovery,” says Vetterli. “Much more work and data are required to learn more about the Higgs-like particle and show that it is indeed the missing link to our understanding of the fundamental structure of matter.

There is one more Canada Foundation for Innovation grant to be announced here, it’s a $1.6M grant for research that will be performed at TRIUMF, according to the Jan. 13, 2013 news release from St. Mary’s University (Halifax, Nova Scotia),

Dr. Rituparna Kanungo’s newest research collaboration has some lofty goals: improve cancer research, stimulate the manufacturing of high-tech Canadian-made instrumentation and help explain the origin of the cosmos.

The Saint Mary’s nuclear physicist’s goal moved one step closer to reality today when the federal government announced $1.6 million in support for an advanced research facility that will allow her to recreate, purify, and condition rare isotopes that haven’t existed on the planet for millions of years.

The federal fiscal support from the Canada Foundation for Innovation together with additional provincial and private sector investment will allow the $4.5 million project to be operational in 2015.

“The facility will dramatically advance Canada’s capabilities for isolating, purifying, and studying short-lived isotopes that hold the key not only for understanding the rules that govern the basic ingredients of our everyday lives but also for crafting new therapies that could target and annihilate cancers cell-by-cell within the human body, “ said Dr Kanungo.

The CANadian Rare-isotope facility with Electron-Beam ion source (CANREB) project is led by Saint Mary’s University partnering with the University of Manitoba and Advanced Applied Physics Solutions, Inc. in collaboration with the University of British Columbia, the University of Guelph, Simon Fraser University, and TRIUMF. TRIUMF is Canada’s national laboratory for particle and nuclear physics. It is owned and operated as a joint venture by a consortium of Canadian universities that includes Saint Mary’s University.

As one of the nation’s top nuclear researchers (she was one of only two Canadians invited to speak at a Nobel Symposium last June about exotic isotopes), Dr. Kanungo has been conducting research at the TRIUMF facility for many years, carrying out analyses from her office at Saint Mary’s University together with teams of students. Her students also often spend semesters at the Vancouver facility.

As the project leader for the new initiative, she said TRIUMF is the ideal location because of its world leading isotope-production capabilities and its ability to produce clean, precise, controlled beams of selected exotic isotopes not readily available anywhere else in the world.

In recent studies in the U.S., some of these isotopes have been shown to have dramatic impact in treating types of cancer, by delivering radioactive payloads directly to the cancerous cells. Canada’s mastery of the technology to isolate, study, and control these isotopes will change the course of healthcare.

An integral part of the project is the creation of a new generation of high resolution spectrometer using precision magnets. Advanced Cyclotron Systems, Inc. a company in British Columbia, has been selected for the work with the hope that the expertise it develops during the venture will empower it to design and build precision-magnet technology products for cutting-edge projects all around the world.

Exciting stuff although it does seem odd that the federal government is spreading largesse when there’s no election in sight. In any case, bravo!

There’s one last piece of news, TRIUMF is welcoming a new member to its board, from its Jan. 14, 2013 news release,

Dr. Sylvain Lévesque, Vice-President of Corporate Strategy at Bombardier Inc., a world-leading manufacturer of innovative transportation solutions, has joined the Board of Management for TRIUMF, Canada’s national laboratory for particle and nuclear physics, for a three-year term.  Owned and operated by a consortium of 17 Canadian universities with core operating funds administered via a contribution agreement through National Research Council Canada, TRIUMF is guided by a Board that includes university vice-presidents of research, prestigious scientists, and leading members of Canada’s private sector.

Paul Young, Chair of TRIUMF’s Board and Vice President, Research at the University of Toronto, said, “We welcome the participation of Sylvain and his extensive experience at Bombardier.  TRIUMF is a national resource for basic research and yet we also fulfill a technological innovation mission for Canada.  Dr. Lévesque will be a valuable addition to the Board.”

Dr. Sylvain Lévesque earned his Ph.D. from MIT in Engineering and worked at McKinsey & Company before joining Bombardier in 1999.  He brings deep experience with large, technical organizations and a passion for science and engineering. [emphasis mine]  He said, “I am excited to work more closely with TRIUMF.  It has a track record of excellence and I am eager to provide guidance on where Canada’s industrial sector might draw greater strength from the laboratory.”

TRIUMF’s Board of Management reflects the unique status of TRIUMF, a laboratory operating for more than forty years as a joint venture from Canada’s leading research universities.  The consortium includes universities from Halifax to Victoria.

Is deep experience like wide experience or is it a whole new kind of experience helpful for ‘getting one’s groove on’? For anyone who’s curious, ‘getting one’s groove on’ involves dancing.

Aptamers and Maria DeRosa

Today’s (Oct. 25, 2011) next interview is with Maria DeRosa of the DeRosa Lab at Carleton University (Ottawa, Canada) where she and her colleagues work on bionanotechnology projects. (The Highlighting the 2011 Dance Your Ph.D. contest posting featured a Ph.D student from her lab who is one of this year’s contest finalists.)

Before proceeding to the interview, here’s a little bit about the DeRosa Lab (from the website homepage),

The first step in the rational design of novel bionanotechnology is to find the right molecular components for the task. Our group seeks to investigate the use of chemically-modified nucleic acid aptamers, single stranded DNA or RNA sequences that specifically bind to a diverse variety of targets, in biosensing and catalysis.

Here’s some information about Dr. DeRosa,

Dr. Maria DeRosa’s research examines a type of nucleic acid called ‘aptamers’ that can fold into 3D nanoscale shapes capable of binding tightly to a specific molecular target.  Her group is focused on developing a better understanding of how these systems and using this information to design useful nanotechnology, like biosensors or “smart” delivery devices.  Dr. DeRosa received her Ph.D in Chemistry from Carleton University in 2003 and was presented with a University Senate Medal. She was awarded an NSERC Postdoctoral Fellowship to do research at the California Institute of Technology from 2004-2005 with Prof. Jackie Barton, a world-leader in DNA sensor research. In 2005, she returned to Carleton as a faculty member in the Chemistry Department. Her research group has received funding from the Natural Sciences and Engineering Research Council (NSERC), the Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA), the Canada Foundation for Innovation (CFI) and Alberta Innovates Biosolutions.  DeRosa was a recipient of the John Charles Polanyi Research Award for new researchers in 2006 and an Ontario Early Researcher Award in 2010.

Here’s the interview,

*   Are you one of those people who always wanted to be a scientist or was this something you discovered later?

I was never one of those people who knew what they wanted to do from an early age.  I thought about being a doctor, pharmacist, plumber, engineer, bank teller…  In high school, I had many great math and science teachers that inspired me to go into science when I started at Carleton University.  Then, in my third year I got a summer job working in Dr. Bob Crutchley’s research lab.  He was a great mentor and it was then that I started seriously thinking about a career as a scientist.  I loved the idea of research, that I was working on a problem and no one knew what the answer would be.  I wanted the answers!

*   How did you get interested in aptamers (and could you briefly describe what they are)?

Aptamers are synthetic pieces of DNA that can recognize and stick to a molecular target.  The targets can vary from things that are very small, like a drug molecule to something much larger, like bacteria or viruses.  Because they can recognize and stick to other molecules, people are interested in using them as receptors for sensors.  I had never even heard of them until about 2005.

After my Ph.D., I went to Caltech to do something called a postdoctoral fellowship.  It was a research position in the lab of Dr. Jackie Barton, one of the world’s top DNA researchers (she just won a National Medal of Science a couple days ago).  She wasn’t working with aptamers but she opened me up to the idea of using DNA in an “unnatural” way.  Most of us, when we are thinking of DNA, we think of our genes and that it is the blueprint for life.  But from a chemistry point of view, DNA is just another material that has certain chemical properties that can be useful for other applications.  In Jackie’s lab, I learned how to make synthetic DNA and I started reading about aptamers.  I found the whole field fascinating and I knew that I wanted to be a part of it.

*   What applications are there for your work? (I noticed that you discussed fertilizers in your TEDxCarleton talk. Is agriculture an area of particular interest?)

Applications for aptamers mostly stem from their ability to bind tightly and selectively to other molecules.  So, they are typically used in technology such as biosensors where they can serve to detect low levels of something, like a toxin or a virus for example, in another matrix.  We’re developing aptamers for the detection of mycotoxins (toxins that come from moulds) in crops and food.  We’re also working on aptamers for norovirus (the virus that causes Norwalk, that awful stomach bug) so that we can catch it if it is in meat and other foods before they get sent off to stores.

We are also trying to use aptamers for triggered delivery of drugs and/or nutrients.  In many cases with drugs, we want them to act on certain cells or tissues and not on others.  So, we need to be able to control where the drug is released in the body.  There is a similar problem in agriculture.  We want to give crops certain nutrients from fertilizers but if we deliver them at the wrong time, they will be washed away and not taken up by the crop.  This leads to major economic losses for the farmer and problems for the environment.  With our work, the idea is that we use the aptamer to control the release of whatever we are delivering.  We incorporate the aptamer into a coating that covers the drug or nutrient.  The aptamer is there to recognize a stimulus that we want to use to release the contents.  For drug delivery, that stimulus might be a cancer cell or a disease biomarker.  For fertilizers, that stimulus might a be a plant signal that corresponds to the plant’s need for nutrients.  (We are working with Dr.Carlos Monreal from Agriculture and Agrifood Canada on the fertilizer project, and he is an expert in these plant signals and ‘smart fertilizers’.)  In the absence of that signal, the coating does not allow the release of the drug or nutrient.  But, once the aptamer recognizes that key signal, the aptamer distorts or destroys the coating and it allows the nutrient to be released.

*   According to the information on your lab website, you are the recipient of Canada Foundation for Innovation (CFI) Leaders Opportunity Fund (LOF) monies. Are these funds being applied to a particular project in your lab or are they used to support your general area of research?

CFI funds helped us to build our facility called the LADDER (Laboratory for Aptamer Discovery and Development of Emerging Research applications).  That funding allowed us to get the state-of-the-art equipment we need to support all of our research projects.  Without CFI funding, our work would not be possible!

*   Given your TEDxCarleton talk and your involvement in the 2011 Canadian Science Writers conference (researchers’ speed dating [I couldn’t confirm it but I’m pretty sure I saw your name listed for this event]), I gather you’re quite interested in public outreach. Why do you think it’s important?

Yes, I was at that ‘speed dating’ event and I am very committed to science outreach.  The public helps to support my research through funding like NSERC and CFI, so I think it is critical that I can explain to them what it is that I do, why it is important, and why their money is well-spent.  The general public may not know what an aptamer is, but they all realize the importance of keeping our food free of toxins or the need to make drugs that are better able to target disease.

*   I noticed that one of your students is a finalist in the Dance your Ph.D 2011 contest. And it’s not the first time. Do you find a lot of scientists with ‘dance’ tendencies are attracted to your lab? Are you one of those scientists?

My students won the competition last year and then they were finalists again this year!  I’m not sure if dancers are attracted to my lab or if my students are just as committed to outreach as I am!  My students are very excited to talk about their research with anyone who will listen.  This contest is a fun way to explain their work to everyday people.  Friends and family, after watching these dances online, have told me that they finally understand what is going on in my lab.  Maybe I should dance more!  (I’m not a dancer and you will not find me in either video…I support them from the sidelines!)

*   Is there anything you would like to add?

Thanks for profiling me and it has been fun!

Maria, thank you for this intriguing peek into your research, the field of DNA nanotechnology, and your (and shared by your students) commitment to public science outreach. I’m very happy you managed to cram the time to answer these questions into your schedule.

Broader Impacts Criterion and informal science education in the US

Broader Impacts Criterion (BIC), a requirement for US National Science Foundation (NSF) grants covers the areas of science education, science outreach, and the promotion of benefits to society. As you might expect there is support and criticism from scientists and the scientific community about having to include BIC in grant proposals, from the American Physical Society News, June 2007 (volume 16, no. 6),

Bob Eisenstein, Chair of APS’s Panel on Public Affairs, was at NSF when the criterion was first put in place in the mid-1990s. He said that the criterion is meant to serve two purposes: first, it forces scientists to think more carefully about the ways in which their work impacts society, and second, it helps provide the public with more information about what scientists are doing.

Fred Cooper, a current NSF program director for theoretical physics, said his personal opinion is that this is a good thing for NSF to do. “I’m very happy to encourage people to think about these things,” he said. He says it is in scientists’ self-interest to do so.

However, some scientists object to research funding being coupled to education or outreach efforts. Mildred Dresselhaus of MIT says she has heard from many scientists who are unhappy with the broader impacts requirements, and who feel they should be funded based on the quality of their research, not for outreach. …

I gather the criticism was serious enough to warrant a review, excerpted from the July 25, 2011 NISE (Nanoscale Informal Science Education) Net blog posting by Carol Lynn Alpert (BIC requirements have an indirect impact on science museums which benefit from subawards and partnerships with researchers and research institutions seeking to fulfill their BIC obligations),

After reviewing comments from 5,100 stakeholders, the NSB [the National Science Board is the NSF’s governing body] has decided to retain both criteria, but to revise them in order to clarify their intent and “connection to NSF’s core principles” (NSF-11-42, available at http://www.nsf.gov/nsb/publications/2011/06_mrtf.jsp).

As stated by the NSB, these core principles and national goals are led by concerns for global economic and workforce competitiveness, and for the first time allow that “broader impacts” may be achieved “through the research itself.”  This phrase has some worrying that a “BIC loophole” has been created, for it allows that the research itself may be “enough” to enhance U.S economic and workforce competitiveness, without the research team needing to specifically incorporate synergistic activities addressing concomitant K-12 education, diversity, or public engagement goals.

On July 13, AAAS [American Association for the Advancement of Science] submitted a letter to the Chairman of the NSB strongly objecting to what I am here referring to as the “BIC loophole.” AAAS said, “While increasing knowledge serves a public good, it is not always clear how publicly funded research can produce broader impacts unless it is applied and/or widely communicated beyond the scholarly community. The current language appears to offer researchers an excuse not to engage in a more thoughtful consideration of the criterion.”

Here’s a link to the full letter from the AAAS.

I find it fascinating that there’s a discussion about this in the US as the concept of scientists engaging in public outreach does not seem to exist in the same way in Canada. I was able to find Canadian science funding agencies that require some public outreach.  NSERC (Natural Sciences and Engineering Research Council) has a general NSERC policy for public communication,

The Institution [receiving the grant] agrees to:

  1. identify, encourage and assist researchers to communicate with media and participate in announcement events to promote Agency-funded research;
  2. inform, at least five working days before the proposed announcement, if feasible, the Agency’s or Agencies’ public affairs or communications division – normally through the Institution’s own public affairs, communications, or research communications department – of announcements of Agency awards, programs and significant research results that the Institution proposes to make;
  3. include appropriate acknowledgement of the appropriate Agency or Agencies in all relevant public communications issued by the Institution;
  4. respect the relevant Agency or Agencies’ obligation under the Communications Policy of the Government of Canada;
  5. respect the relevant Agency or Agencies’ prerogative to make the first public announcement of its awards, grants and programs, when the relevant Minister declines to do so. It is the purview of a Minister or the Minister’s designate to make public announcements of all federal expenditures; and
  6. share with the Agency or Agencies any promotional material for the general public that is based on Agency-funded research.

So, this NSERC policy is aimed more at the universities and other institutions not the individual researcher.  Also, it seems to be more a guideline or general rule which provides a bit of a contrast  with the Canada Foundation for Innovation (CFI) which lists public communication as a requirement for funding. From the CFI Policy and Program Guide, December 2010,

As part of filing their annual institutional reports (see secion 7.3.2), institutions must provide the CFI with information on the communication activities undertaken in the previous year, along with activities planned for the coming year that are designed to showcase the impacts and outcomes of CFI investments. Institutions are asked to provide information on media activity, publications (print and online) and special events. This information assists the CFI in identifying national trends in research communications, as well as opportunities for collaboration on communications initiatives with institutions. (p. 81)

Not enough money for Canadian business schools? Canada Foundation for Innovation replies

March 22, 2011 (http://www.frogheart.ca/?p=3151)  I posted about a  interview with Roger Martin, Dean of the Rotman School of Management at the University of Toronto, about Canadian business schools, innovation and research that was published in the March 16, 2011, Globe & Mail newspaper. (http://www.theglobeandmail.com/report-on-business/managing/business-education/canada-will-shrivel-under-business-school-neglect-dean-says/article1942997/page2/). In response to this interview question, Martin made the claim the Canada Foundation for Innovation funded a greater numbers of arts funding requests and humanities funding requests over business funding requests,

Wouldn’t some people argue leadership comes as much from the liberal arts and other social sciences?

We’re getting liberal arts education, but the arts are getting an incredibly rich allocation of the money at all levels. It is only business that is not.

Of all the money given out by the Canada Foundation for Innovation [CFI], a big federal grants program, nine times more has gone to arts and literature than to business. I am not even talking social and human sciences – that is 41 times.

The view is that having educated managers is not relevant to economic success. We assume we need educated lawyers to have good law firms; we need educated scientists to have good science; you need educated engineers to have good engineering, but in business it is assumed you do not need education.

There was a response from the president and CEO (chief executive officer) of the CFI in the March 18, 2011 issue of the Globe & Mail. The paper published an excerpt, this is the full text of the response (received by request from the CFI media relations coordinator, Yves Melanson),

I read with interest the report of your interview with Roger Martin in Wednesday’s edition of the Globe and Mail on the “Lack of government research funding for business education”. As President and CEO of the Canada Foundation for Innovation (CFI), I was particularly interested by the reference made to the CFI.

Your readers might be interested to know that the Canada Foundation for Innovation was created by the Government of Canada to support state-of-the-art infrastructure (facilities and equipment), in universities, colleges, research hospitals and non-profit research institutions, allowing them to: a) attract/retain the world’s top talent; b) conduct world-class research and technology development that leads to social, economic and environmental benefits to Canada; c) train the next generation of highly qualified personnel; and d) support private-sector innovation that strengthens Canada’s position in today’s knowledge economy.

The CFI is called upon to invest in equipment, laboratories, information databases and computing systems required by all researchers, including those in our business schools. The CFI does not allocate funding to any specific discipline or area of research. Applications are submitted by the institutions to the CFI and funding is awarded through highly competitive programs. All applications, whether they are in health, science or business administration are judged according to the same criteria – excellence and the benefits to Canada. Moreover, the CFI requires that applications be well aligned with the university’s overall Strategic Research Plan.

While the success rate of applications from business schools compares favourably to the overall CFI success rate, the number of applications from business schools is surprisingly low. Of the more than 900 applications in the humanities and social sciences that have been submitted to the CFI to date, only 50 came from business schools (with a 70% success rate). [emphasis mine] Researchers in our business schools have received CFI research infrastructure funding, and, given the high quality of their research, will no doubt receive more in the future. The CFI’s doors are open to business school researchers, and will remain so, but they must apply!

Gilles G. Patry
President and CEO
Canada Foundation for Innovation

I haven’t seen responses from the other funding agencies but based on this one from the CFI, it would seem that the business schools are not pursuing the grants available to them for research.