Tag Archives: dendrites

It’s not all about simulating the synapse for neuromorphic (brainlike) computing: presenting dendritic integration

Michael Berger’s May 20, 2026 Nanowerk Spotlight article features a new (to me) aspect (or, if you prefer, challenge) to neuromorphic computing, Note: A link has been removed,

Efforts to design computing systems that operate more like the brain have pushed engineers to rethink how information is processed, transmitted, and stored. Biological neurons are not simple relays. Their ability to process input relies not just on synapses—the connections between neurons—but also on dendrites. These branching structures collect and integrate signals across both time and space, shaping how a neuron responds.

Most neuromorphic devices developed so far have focused on mimicking synaptic functions. Dendritic behavior, which governs how multiple inputs are combined and modulated, remains less explored. This gap limits the capacity of neuromorphic hardware to emulate the full computational complexity of biological neurons.

For anyone unfamiliar with dendrites, here’s a description from the Dendrite Wikipedia entry, which follows the image, Note: Links not included in the caption for the image have been removed,

Credity: Curtis Neveu – Own work. Caption: The neuron contains dendrites that receives information, a cell body called the soma, an an axon that sends information. Schwann cells make activity move faster down axon. Synapses allow neurons to activate other neurons. The dendrites receive a signal, the axon hillock funnels the signal to the initial segment and the initial segment triggers the activity (action potential) that is sent along the axon towards the synapse. Please see learnbio.org for interactive version. CC BY-SA 4.0
File:Anatomy of neuron.png
Created: 17 May 2022
Uploaded: 17 May 2022

A dendrite (from Greek δένδρον déndron, “tree”) or dendron is a branched cytoplasmic process that extends from a nerve cell that propagates the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project. Electrical stimulation is transmitted onto dendrites by upstream neurons (usually via their axons) via synapses which are located at various points throughout the dendritic tree.

Dendrites play a critical role in integrating these synaptic inputs and in determining the extent to which action potentials are produced by the neuron.[1]

Berger’s May 20, 2026 article explains how scientists are attempting to create artificial dendrites, Note: Links have been removed,

Artificial dendrites are difficult to construct. Unlike synapses, which can often be replicated with resistive memory elements (memristors), dendrites require spatially distributed signal processing and sensitivity to the timing of input spikes. Biological dendrites perform this by managing ion flow across complex membrane structures, often with localized chemical and electrical variations. Traditional electronic systems, which rely on electrons in solid-state circuits, struggle to reproduce these dynamics.

Ionic devices offer a more faithful analogue. In particular, nanofluidic memristors—devices that transport ions through confined channels—can mimic how neurons regulate ionic currents. Prior work has shown that such systems can simulate synaptic plasticity and memory. Yet most rely on electrical stimulation, which adds complexity to control circuitry.

In contrast, light offers a clean, contactless way to manipulate ion behavior. Optogenetics, a biological technique that uses light to activate ion channels in neurons, has shown how effective this can be. Researchers have started applying similar principles to synthetic systems, but artificial dendrites with full spatiotemporal integration remain rare.

A study published in Advanced Materials (“Optogenetics‐Inspired Nanofluidic Artificial Dendrite with Spatiotemporal Integration Functions”) introduces a nanofluidic device that addresses this challenge. Developed by a team at Northeast Normal University [NENU], the system integrates layered graphene oxide (GO) into a flexible polydimethylsiloxane (PDMS) matrix. It uses light to control sodium ion (Na⁺) transport through nanochannels. This approach simulates how dendrites integrate signals from different spatial locations and over time. It also lays the groundwork for more advanced neuromorphic machines that include artificial sensory-motor reflexes.

This work shows how optical modulation of ionic pathways can be used to create functional artificial dendrites. It opens a path toward more realistic neural circuits in hardware, capable not just of memory and learning, but of the nuanced signal processing required for perception and motor control. As components like this are refined, they could play a central role in building autonomous systems that interact more naturally with their environment.

Here’s a link to and a citation for the paper,

Optogenetics-Inspired Nanofluidic Artificial Dendrite with Spatiotemporal Integration Functions by Zhuangzhuang Li, Ya Lin, Xuanyu Shan, Zhongqiang Wang, Xiaoning Zhao, Ye Tao, Haiyang Xu, Yichun Liu. Advanced Materials First published: 16 May 2025 Online Version of Record before inclusion in an issue 2502438 DOI: https://doi.org/10.1002/adma.202502438

This paper is behind a paywall.

If you have the time, Berger’s May 20, 2026 article provides more detail about the device.

Artificial synapse based on tantalum oxide from Korean researchers

This memristor story comes from South Korea as we progress on the way to neuromorphic computing (brainlike computing). A Sept. 7, 2018 news item on ScienceDaily makes the announcement,

A research team led by Director Myoung-Jae Lee from the Intelligent Devices and Systems Research Group at DGIST (Daegu Gyeongbuk Institute of Science and Technology) has succeeded in developing an artificial synaptic device that mimics the function of the nerve cells (neurons) and synapses that are response for memory in human brains. [sic]

Synapses are where axons and dendrites meet so that neurons in the human brain can send and receive nerve signals; there are known to be hundreds of trillions of synapses in the human brain.

This chemical synapse information transfer system, which transfers information from the brain, can handle high-level parallel arithmetic with very little energy, so research on artificial synaptic devices, which mimic the biological function of a synapse, is under way worldwide.

Dr. Lee’s research team, through joint research with teams led by Professor Gyeong-Su Park from Seoul National University; Professor Sung Kyu Park from Chung-ang University; and Professor Hyunsang Hwang from Pohang University of Science and Technology (POSTEC), developed a high-reliability artificial synaptic device with multiple values by structuring tantalum oxide — a trans-metallic material — into two layers of Ta2O5-x and TaO2-x and by controlling its surface.

A September 7, 2018 DGIST press release (also on EurekAlert), which originated the news item, delves further into the work,

The artificial synaptic device developed by the research team is an electrical synaptic device that simulates the function of synapses in the brain as the resistance of the tantalum oxide layer gradually increases or decreases depending on the strength of the electric signals. It has succeeded in overcoming durability limitations of current devices by allowing current control only on one layer of Ta2O5-x.

In addition, the research team successfully implemented an experiment that realized synapse plasticity [or synaptic plasticity], which is the process of creating, storing, and deleting memories, such as long-term strengthening of memory and long-term suppression of memory deleting by adjusting the strength of the synapse connection between neurons.

The non-volatile multiple-value data storage method applied by the research team has the technological advantage of having a small area of an artificial synaptic device system, reducing circuit connection complexity, and reducing power consumption by more than one-thousandth compared to data storage methods based on digital signals using 0 and 1 such as volatile CMOS (Complementary Metal Oxide Semiconductor).

The high-reliability artificial synaptic device developed by the research team can be used in ultra-low-power devices or circuits for processing massive amounts of big data due to its capability of low-power parallel arithmetic. It is expected to be applied to next-generation intelligent semiconductor device technologies such as development of artificial intelligence (AI) including machine learning and deep learning and brain-mimicking semiconductors.

Dr. Lee said, “This research secured the reliability of existing artificial synaptic devices and improved the areas pointed out as disadvantages. We expect to contribute to the development of AI based on the neuromorphic system that mimics the human brain by creating a circuit that imitates the function of neurons.”

Here’s a link to and a citation for the paper,

Reliable Multivalued Conductance States in TaOx Memristors through Oxygen Plasma-Assisted Electrode Deposition with in Situ-Biased Conductance State Transmission Electron Microscopy Analysis by Myoung-Jae Lee, Gyeong-Su Park, David H. Seo, Sung Min Kwon, Hyeon-Jun Lee, June-Seo Kim, MinKyung Jung, Chun-Yeol You, Hyangsook Lee, Hee-Goo Kim, Su-Been Pang, Sunae Seo, Hyunsang Hwang, and Sung Kyu Park. ACS Appl. Mater. Interfaces, 2018, 10 (35), pp 29757–29765 DOI: 10.1021/acsami.8b09046 Publication Date (Web): July 23, 2018

Copyright © 2018 American Chemical Society

This paper is open access.

You can find other memristor and neuromorphic computing stories here by using the search terms I’ve highlighted,  My latest (more or less) is an April 19, 2018 posting titled, New path to viable memristor/neuristor?

Finally, here’s an image from the Korean researchers that accompanied their work,

Caption: Representation of neurons and synapses in the human brain. The magnified synapse represents the portion mimicked using solid-state devices. Credit: Daegu Gyeongbuk Institute of Science and Technology(DGIST)