Tag Archives: Larry Bell

NISE Net, the acronym remains the same but the name changes

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NISE Net, the US Nanoscale Informal Science Education Network is winding down the nano and refocussing on STEM (science, technology, engineering, and mathematics). In short, NISE Net will now stand for National Informal STEM Education Network. Here’s more from the Jan. 7, 2016 NISE Net announcement in the January 2016 issue of the Nano Bite,

COMMUNITY NEWS

NISE Network is Transitioning to the National Informal STEM Education Network

Thank you for all the great work you have done over the past decade. It has opened up totally new possibilities for the decade ahead.

We are excited to let you know that with the completion of NSF funding for the Nanoscale Informal Science Education Network, and the soon-to-be-announced NASA [US National Aeronautics and Space Administration]-funded Space and Earth Informal STEM Education project, the NISE Network is transitioning to a new, ongoing identity as the National Informal STEM Education Network! While we’ll still be known as the NISE Net, network partners will now engage audiences across the United States in a range of STEM topics. Several new projects are already underway and others are in discussion for the future.

Current NISE Net projects include:

  • The original Nanoscale Informal Science Education Network (NISE Net), focusing on nanoscale science, engineering, and technology (funded by NSF and led by the Museum of Science, Boston)
  • Building with Biology, focusing on synthetic biology (funded by NSF and led by the Museum of Science with AAAS [American Association for the Advancement of Science], BioBuilder, and SynBerc [emphases mine])
  • Sustainability in Science Museums (funded by Walton Sustainability Solutions Initiatives and led by Arizona State University)
  • Transmedia Museum, focusing on science and society issues raised by Mary Shelley’s Frankenstein (funded by NSF and led by Arizona State University)
  • Space and Earth Informal STEM Education (funded by NASA and led by the Science Museum of Minnesota)

The “new” NISE Net will be led by the Science Museum of Minnesota in collaboration with the Museum of Science and Arizona State University. Network leadership, infrastructure, and participating organizations will include existing Network partners, and others attracted to the new topics. We will be in touch through the newsletter, blog, and website in the coming months to share more about our plans for the Network and its projects.

In the mean time, work is continuing with partners within the Nanoscale Informal Science Education Network throughout 2016, with an award end date of February 28, 2017. Although there will not be a new NanoDays 2016 kit, we encourage our partners to continue to engage audiences in nano by hosting NanoDays events in 2016 (March 26 – April 3) and in the years ahead using their existing kit materials. The Network will continue to host and update nisenet.org and the online catalog that includes 627 products of which 366 are NISE Net products (public and professional), 261 are Linked products, and 55 are Evaluation and Research reports. The Evaluation and Research team is continuing to work on final Network reports, and the Museum and Community Partnerships project has awarded 100 Explore Science physical kits to partners to create new or expanded collaborations with local community organizations to reach new underserved audiences not currently engaged in nano. These collaborative projects are taking place spring-summer 2016.

Thank you again for making this possible through your great work.

Best regards,

Larry Bell, Museum of Science
Paul Martin, Science Museum of Minnesota and
Rae Ostman, Arizona State University

As noted in previous posts, I’m quite interested in the synthetic biology focus the network has established in the last several months starting in late Spring 2015 and the mention of two (new-to-me) organizations, BioBuilder and Synberc piqued my interest.

I found this on the About the foundation page of the BioBuilder website,

What’s the best way to solve today’s health problems? Or hunger challenges? Address climate change concerns? Or keep the environment cleaner? These are big questions. And everyone can be part of the solutions. Everyone. Middle school students, teens, high school teachers.

At BioBuilder, we teach problem solving.
We bring current science to the classroom.
We engage our students to become real scientists — the problem solvers who will change the world.
At BioBuilder, we empower educators to be agents of educational reform by reconnecting teachers all across the country with their love of teaching and their own love of learning.

Synthetic biology programs living cells to tackle today’s challenges. Biofuels, safer foods, anti-malarial drugs, less toxic cancer treatment, biodegradable adhesives — all fuel young students’ imaginations. At BioBuilder, we empower students to tackle these big questions. BioBuilder’s curricula and teacher training capitalize on students’ need to know, to explore and to be part of solving real world problems. Developed by an award winning team out of MIT [Massachusetts Institute of Technology], BioBuilder is taught in schools across the country and supported by thought leaders in the STEM community.

BioBuilder proves that learning by doing works. And inspires.

As for Synberc, it is the Synthetic Biology Engineering Research Center and they has this to say about themselves on their About us page (Note: Links have been removed),

Synberc is a multi-university research center established in 2006 with a grant from the National Science Foundation (NSF) to help lay the foundation for synthetic biology Our mission is threefold:

develop the foundational understanding and technologies to build biological components and assemble them into integrated systems to accomplish many particular tasks;
train a new cadre of engineers who will specialize in engineering biology; and
engage the public about the opportunities and challenges of engineering biology.

Just as electrical engineers have made it possible for us to assemble computers from standardized parts (hard drives, memory cards, motherboards, and so on), we envision a day when biological engineers will be able to systematically assemble biological components such as sensors, signals, pathways, and logic gates in order to build bio-based systems that solve real-world problems in health, energy, and the environment.

In our work, we apply engineering principles to biology to develop tools that improve how fast — and how well — we can go through the design-test-build cycle. These include smart fermentation organisms that can sense their environment and adjust accordingly, and multiplex automated genome engineering, or MAGE, designed for large-scale programming and evolution of cells. We also pursue the discovery of applications that can lead to significant public benefit, such as synthetic artemisinin [emphasis mine], an anti-malaria drug that costs less and is more effective than the current plant-derived treatment.

The reference to ‘synthetic artemisinin’ caught my eye as I wrote an April 12, 2013 posting featuring this “… anti-malaria drug …” and the claim that the synthetic “… costs less and is more effective than the current plant-derived treatment” wasn’t quite the conclusion journalist, Brendan Borrell arrived at. Perhaps there’s been new research? If so, please let me know.

Chad Mirkin’s periodic table of modified nucleic acid nanoparticles

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Chad Mirkin has been pushing his idea for a new periodic table of ‘nanoparticles’ since at least Feb. 2013 (I wrote about this and some of Mirkin’s other work in my Feb. 19, 2013 posting) when he presented it at the 2013 American Association for the Advancement of Science (AAAS) annual meeting in Boston, Massachusetts. From a Feb. 17, 2013 news item on ScienceDaily,

Northwestern University’s Chad A. Mirkin, a leader in nanotechnology research and its application, has developed a completely new set of building blocks that is based on nanoparticles and DNA. Using these tools, scientists will be able to build — from the bottom up, just as nature does — new and useful structures.

Mirkin will discuss his research in a session titled “Nucleic Acid-Modified Nanostructures as Programmable Atom Equivalents: Forging a New Periodic Table” at the American Association for the Advancement of Science (AAAS) annual meeting in Boston.

“We have a new set of building blocks,” Mirkin said. “Instead of taking what nature gives you, we can control every property of the new material we make. [emphasis mine] We’ve always had this vision of building matter and controlling architecture from the bottom up, and now we’ve shown it can be done.”

Mirkin seems a trifle grandiose; I’m hoping he doesn’t have any grand creation projects that require seven days.

Getting back to the new periodic table, the Feb. 13, 2013 Northwestern University news release by Megan Fellman, which originated the news item,  provides a few more details,

Using nanoparticles and DNA, Mirkin has built more than 200 different crystal structures with 17 different particle arrangements. Some of the lattice types can be found in nature, but he also has built new structures that have no naturally occurring mineral counterpart.
….
Mirkin can make new materials and arrangements of particles by controlling the size, shape, type and location of nanoparticles within a given particle lattice. He has developed a set of design rules that allow him to control almost every property of a material.

New materials developed using his method could help improve the efficiency of optics, electronics and energy storage technologies. “These same nanoparticle building blocks have already found wide-spread commercial utility in biology and medicine as diagnostic probes for markers of disease,” Mirkin added.

With this present advance, Mirkin uses nanoparticles as “atoms” and DNA as “bonds.” He starts with a nanoparticle, which could be gold, silver, platinum or a quantum dot, for example. The core material is selected depending on what physical properties the final structure should have.

He then attaches hundreds of strands of DNA (oligonucleotides) to the particle. The oligonucleotide’s DNA sequence and length determine how bonds form between nanoparticles and guide the formation of specific crystal lattices.

“This constitutes a completely new class of building blocks in materials science that gives you a type of programmability that is extraordinarily versatile and powerful,” Mirkin said. “It provides nanotechnologists for the first time the ability to tailor properties of materials in a highly programmable way from the bottom up.”

Mirkin and his colleagues have since published a paper about this new periodic table in Angewandte Chemie (May 2013). And, earlier today (July 5, 2013) Philip Ball writing (A self-assembled periodic table) for the Royal Society of Chemistry provided a critique of the idea while supporting it in principle,

Mirkin and his colleagues perceive the pairing of [DNA] strands as somewhat analogous to the covalent pairing of electrons and call their DNA-tagged nanoparticles programmable atom equivalents (PAEs). These PAEs may bind to one another according to particular combinatorial rules and Mirkin proposes a kind of periodic table of PAEs that systematises their possible interactions and permutations.
Well, it’s not hard to start enumerating ways in which PAEs are unlike atoms. Most fundamentally, perhaps, the bonding propensity of a PAE need bear no real relation to the ‘atom’ (the nanoparticle) with which it is associated: a given nanoparticle might be paired with any other, and there’s nothing periodic about those tendencies.

I recommend reading Ball’s piece for the way he analyzes the weaknesses and for why he thinks the effort to organize PAEs conceptually is worthwhile.

For the curious, here’s a link to and a citation for the researchers’ published paper,

Nucleic Acid-Modified Nanostructures as Programmable Atom Equivalents: Forging a New “Table of Elements by Robert J. Macfarlane, Matthew N. O’Brien, Dr. Sarah Hurst Petrosko, and Prof. Chad A. Mirkin. Angewandte Chemie International Edition Volume 52, Issue 22, pages 5688–5698, May 27, 2013. Article first published online: 2 MAY 2013 DOI: 10.1002/anie.201209336

Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

This article is behind a paywall.

One final comment, this is not the first ‘nanoparticle table of elements’.  Larry Bell mentioned one in his Dec. 7, 2010 NISENet (Nanoscale Informal Science Education Network) blog posting,

The focus of today’s sessions at NSF’s [US National Science Foundation] meeting of nanoscale science and engineering grantees focuses on putting the science to practical use. First up this morning is nanomanufacturing. Mark Tuonimen from the University of Massachusetts at Amherst gave a talk about the Nanoscale Manufacturing Network and one of his images caught my imagination. This image, which comes from the draft Nano2 vision document on the next decade of nanoscale research, illustrates and idea that is sometimes referred to as a periodic table of nanoparticles.

[downloaded from http://www.nisenet.org/blogs/observations_insights/periodic_table_nanoparticles]

[downloaded from http://www.nisenet.org/blogs/observations_insights/periodic_table_nanoparticles]

Bell goes on to describe one way in which a nanoparticle table of elements would have to differ from the traditional chemistry table.

Bumper crop of nano news from NISE Net

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The January issue of the NISE Net (Nanoscale Informal Science Education Network) newsletter features information about a new resource for scientists who need to talk or communicate about their work, Mastering Science and Public Presentations is a video. This talk was given by Tim Masters of Spoken Science at Duke University in the summer of 2010.

Larry Bell on his NISE Net blog discusses some of the meetings (National Science Foundation and National Nanotechnology Initiative) he attended in Washington, DC. I found the one about a Periodic Table of Nanoparticles particularly interesting as it includes an image which features the particles in 3 dimensions representing shape, size, and composition.

There’s a very good nanotechnology article by Corinna Wu in the American Association for Engineering Education (ASEE) magazine, PRISM, Peril in Small Places; What dangers lurk in our expanding use of nanotechnology? It does have an ominous title but the writer does a good job of covering the positive and exciting aspects as well as the risks. From the article,

The wonder of nanotechnology is the abundance of materials, devices, and systems made possible by controlling and manipulating matter at the atomic and molecular levels. But with that wonder comes concern that these now ubiquitous nanoparticles could spread new hazardous pollutants that threaten health and the environment. “We’re trying to say, ‘These are new materials. We don’t know if there’s a problem, so let’s ask now,’” says Sally Tinkle, senior science adviser at the National Institute for Environmental Health Sciences, part of the National Institutes of Health. With prodding from the National Research Council and other institutions, inquiry into the health and environmental effects of nanotechnology has gone hand in hand with research on potential applications. The work is interdisciplinary, and engineers play a critical role. By helping to figure out what makes a nanoparticle toxic, they can, for instance, design nanoparticles that kill cancer cells yet don’t harm healthy tissues, or that remove pollutants from soil without poisoning wildlife.

It’s focused on the US scene and, one quibble, I’m not sure about some of the numbers. (For example, Wu gives a value for the number of nanotechnology products on the market but offers no details as to how this number was derived or where it came from.)

There’s a four-part series, Making Stuff, that’s going to be broadcast as part of the NOVA program on PBS. It starts Jan. 19, 2010. From the website,

Invisibility cloaks. Spider silk that is stronger than steel. Plastics made of sugar that dissolve in landfills. Self-healing military vehicles. Smart pills and micro-robots that zap diseases. Clothes that monitor your mood. What will the future bring, and what will it be made of? In NOVA’s four-hour series, “Making Stuff,” popular New York Times technology reporter David Pogue takes viewers on a fun-filled tour of the material world we live in, and the one that may lie ahead. Get a behind-the-scenes look at scientific innovations ushering in a new generation of materials that are stronger, smaller, cleaner, and smarter than anything we’ve ever seen.

Beginning January 19, 2011, NOVA will premiere the new four-hour series on consecutive Wednesday nights at 9 pm ET/PT on PBS (check local listings): “Making Stuff: Stronger, Smaller, Cleaner, Smarter.”

I wonder if they’ve made any changes to the series. After previewing it a few months ago, Andrew Maynard at 2020 Science featured the program in his Nov. 2, 2010 posting and it provoked a bit of a discussion about how to present science. From the posting,

Last week while at the NISE Net network-wide meeting, I was fortunate enough to see a preview of part of NOVA’s forthcoming series Making Stuff. The series focuses on the wonders of modern materials science. But rather than coming away enthralled by the ingenuity of scientists, I found myself breaking out in a cold sweat as I watched something that set my science-engagement alarm-bells ringing: New York Times tech reporter and host David Pogue enthusing about splicing spider genes into a goat so it produces silk protein-containing milk, then glibly drinking the milk while joking about transforming into Spider Man.

I was sitting there thinking, “You start with a spider – not everyone’s favorite creature. And you genetically cross it with a goat – dangerous territory at the best of times. Then you show a middle aged dude drinking the modified milk from a transgenic animal and having a laugh about it. And all this without any hint of a question over the wisdom or ramifications of what’s going on? Man, this is going to go down well!”

Andrew goes on to ask if his reaction was justified. Comments ensued including one from the producer of the series, Chris Schmidt.

Now, the nano haiku. Again this month there are two:

Asian hornets are
powered by nano solar
at the sun’s zenith.

by Frank Kusiak of the Lawrence Hall of Science. This Haiku relates to the BBC article Oriental hornets powered by ‘solar energy’.

After reading about the use of cinnamon in the production of gold nanoparticles, Vrylena Olney got hungry – and creative:

Cinnamon: good for
pumpkin pie, Moroccan stew,
nanoparticles.

Nano Science Cafe workshop starts and other NISE Net tidbits

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I signed up for an online workshop on how to host and produce a Nano Science Café that the Nanoscale Informal Science Education Network (NISE Net) holds. It started this Monday and so far we’ve been introducing ourselves (approximately 80 people are signed up) and people are sharing ideas about how to hold these events successfully.  Most of the participants are located in the US although there are two Canucks (me and someone from Ontario). Of course, not everyone has introduced themselves yet.

There’s a blog posting by Larry Bell about NISE Net’s increasing focus on nano’s societal implications,

Just about a year ago NISE Net launched an expanded collaboration with the Center for Nanotechnology in Society and you’ll hear more about upcoming activities in the months ahead. The conversation started when staff from seven science centers brought cart demos and stage presentations to the S.NET conference in Seattle on Labor Day weekend last year. S.NET is a new professional society for the study of nanoscience and emerging technologies in areas of the social sciences and humanities. I was a little naive and thought the participants were all social scientists, but learned that many were historians, political scientists, philosophers, and ethicists and really not social scientists.

I’m not entirely certain what to make of either NISE Net’s interest or S.NET (Society for the Study of Nanoscience and Emerging Technologies) since this first meeting seems to have be focused primarily on hands-on demos and public outreach initiatives. There will be a 2nd annual S.NET meeting in 2010 (from the conference info.),

Second Annual Conference of the Society for the Study of Nanoscience and Emerging Technologies

Darmstadt, Germany – Sept 29 to Oct 2, 2010

(Wednesday afternoon 2pm through Saturday afternoon 4pm)

The plenary speakers and program committee lists a few names I’ve come across,

This year’s plenary speakers are Armin Grunwald, Richard Jones [has written a book about nanotechnology titled Soft Machines and maintains a blog also titled Soft Machines], Andrew Light, Bernard Stiegler, and Jan Youtie.

Program Committee

Diana Bowman (Public Health and Law, University of Melbourne, Australia)

Julia Guivant (Sociology and Political Science, Santa Catarina, Brazil)

David Guston (Political Science/Center for Nanotechnology in Society, Arizona State University, USA) [guest blogged for Andrew Maynard at 2020 Science]

Barbara Herr Harthorn (Feminist Studies, Anthropology, Sociology/Center for Nanotechnology in Society,University of California Santa Barbara, USA)

Brice Laurent (Sociology, Mines ParisTech, France)

Colin Milburn (English, University of California Davis, USA)[has proposed a nanotechnology origins story which pre-dates Richard Feynman’s famous speech, There’s plenty of room at the bottom]

Cyrus Mody (History, Rice University, United USA)

Alfred Nordmann (Philosophy, nanoOffice, NanoCenter, Technische Universität Darmstadt and University of South Carolina – chair)

Ingrid Ott (Economics, Karlsruhe Institute of Technology, Germany – co-chair)

Arie Rip (Philosophy of Science and Technology, University of Twente, Netherlands) [read a nano paper where he introduced me to blobology and this metaphor for nanotechnology ‘furniture of the world’]

Ursula Weisenfeld (Business Administration, Leuphana Universität, Lüneburg, Germany)

This looks promising and I wish the good luck with the conference.

As far conferences go, there’s another one for the Association of Science and Technology Centers (ASTC) in Hawaii, Oct 3 – 5, 2010, which will feature some NISE Net sessions and workshops . You can check out the ASTC conference details here.

Here’s the monthly NISE Net nano haiku,

Vocabulary
Kit kit kit kit kit kit kit
There are no nodes now.

by Anders Liljeholm of the Oregon Museum of Science and Industry. Those of you who may not remember that our regional hubs used to be call nodes (or those looking to brush up on their NISE Net vocabulary in general) can check out the NISE Net Glossary in the nisenet.org catalog.