Tag Archives: molecular nanotechnology

2016 Nobel Chemistry Prize for molecular machines

Wednesday, Oct. 5, 2016 was the day three scientists received the Nobel Prize in Chemistry for their work on molecular machines, according to an Oct. 5, 2016 news item on phys.org,

Three scientists won the Nobel Prize in chemistry on Wednesday [Oct. 5, 2016] for developing the world’s smallest machines, 1,000 times thinner than a human hair but with the potential to revolutionize computer and energy systems.

Frenchman Jean-Pierre Sauvage, Scottish-born Fraser Stoddart and Dutch scientist Bernard “Ben” Feringa share the 8 million kronor ($930,000) prize for the “design and synthesis of molecular machines,” the Royal Swedish Academy of Sciences said.

Machines at the molecular level have taken chemistry to a new dimension and “will most likely be used in the development of things such as new materials, sensors and energy storage systems,” the academy said.

Practical applications are still far away—the academy said molecular motors are at the same stage that electrical motors were in the first half of the 19th century—but the potential is huge.

Dexter Johnson in an Oct. 5, 2016 posting on his Nanoclast blog (on the IEEE [Institute of Electrical and Electronics Engineers] website) provides some insight into the matter (Note: A link has been removed),

In what seems to have come both as a shock to some of the recipients and a confirmation to all those who envision molecular nanotechnology as the true future of nanotechnology, Bernard Feringa, Jean-Pierre Sauvage, and Sir J. Fraser Stoddart have been awarded the 2016 Nobel Prize in Chemistry for their development of molecular machines.

The Nobel Prize was awarded to all three of the scientists based on their complementary work over nearly three decades. First, in 1983, Sauvage (currently at Strasbourg University in France) was able to link two ring-shaped molecules to form a chain. Then, eight years later, Stoddart, a professor at Northwestern University in Evanston, Ill., demonstrated that a molecular ring could turn on a thin molecular axle. Then, eight years after that, Feringa, a professor at the University of Groningen, in the Netherlands, built on Stoddardt’s work and fabricated a molecular rotor blade that could spin continually in the same direction.

Speaking of the Nobel committee’s selection, Donna Nelson, a chemist and president of the American Chemical Society told Scientific American: “I think this topic is going to be fabulous for science. When the Nobel Prize is given, it inspires a lot of interest in the topic by other researchers. It will also increase funding.” Nelson added that this line of research will be fascinating for kids. “They can visualize it, and imagine a nanocar. This comes at a great time, when we need to inspire the next generation of scientists.”

The Economist, which appears to be previewing an article about the 2016 Nobel prizes ahead of the print version, has this to say in its Oct. 8, 2016 article,

BIGGER is not always better. Anyone who doubts that has only to look at the explosion of computing power which has marked the past half-century. This was made possible by continual shrinkage of the components computers are made from. That success has, in turn, inspired a search for other areas where shrinkage might also yield dividends.

One such, which has been poised delicately between hype and hope since the 1990s, is nanotechnology. What people mean by this term has varied over the years—to the extent that cynics might be forgiven for wondering if it is more than just a fancy rebranding of the word “chemistry”—but nanotechnology did originally have a fairly clear definition. It was the idea that machines with moving parts could be made on a molecular scale. And in recognition of this goal Sweden’s Royal Academy of Science this week decided to award this year’s Nobel prize for chemistry to three researchers, Jean-Pierre Sauvage, Sir Fraser Stoddart and Bernard Feringa, who have never lost sight of nanotechnology’s original objective.

Optimists talk of manufacturing molecule-sized machines ranging from drug-delivery devices to miniature computers. Pessimists recall that nanotechnology is a field that has been puffed up repeatedly by both researchers and investors, only to deflate in the face of practical difficulties.

There is, though, reason to hope it will work in the end. This is because, as is often the case with human inventions, Mother Nature has got there first. One way to think of living cells is as assemblies of nanotechnological machines. For example, the enzyme that produces adenosine triphosphate (ATP)—a molecule used in almost all living cells to fuel biochemical reactions—includes a spinning molecular machine rather like Dr Feringa’s invention. This works well. The ATP generators in a human body turn out so much of the stuff that over the course of a day they create almost a body-weight’s-worth of it. Do something equivalent commercially, and the hype around nanotechnology might prove itself justified.

Congratulations to the three winners!

David Koepsell: nanotechnology brings the intellectual property regime to an end

David Koepsell, author of Innovation and Nanotechnology: Converging Technologies and the End of Intellectual Property, is a philosopher, attorney, and educator who teaches at the Delft University of Technology (the Netherlands). He is also author of Who Owns You? The Corporate Gold Rush to Patent Your Genes.

In a Feb. 27, 2012 interview with Dr. J (James Hughes, executive director of the Institute of Ethics for Emerging Technologies [IEET] and producer/interviewer for Changesurfer radio), Koepsell discussed his book about nanotechnology and the disappearance of intellectual property regimes in a 28 min. 51 sec. podcast.

Koepsell and Dr. J provided a good description of converging technologies so I’m going to plunge in without much introduction.

I wasn’t expecting to hear about Marxism and the means of production but there it was, mentioned in the context of a near future society where manufacturing can be done by anyone, anywhere by means of molecular manufacturing or by means of 3D fabrication, or etc. The notion is that production will be democratized as will the intellectual property regime. There were several mentions of the state (government) no longer having control in the future over intellectual property, specifically patents and copyrights, and some discussion of companies that guard their intellectual property jealously. (I have commented on the intellectual property topic, most recently,  in my Patents as weapons and obstacles posting in October 2011. Koepsell is mentioned in this posting.)

Both Koepsell and the interviewer (Dr. J) mentioned the possibility of widespread economic difficulty as jobs disappear due to the disappearance of manufacturing and other associated jobs as people can produce their own goods (much like you can with Star Trek’s replicators). But it did seem they mentioned job loss somewhat blithely, secure in their own careers as academics who as a group are not known for their manufacturing prowess or, for that matter, the production of any goods whatsoever.

It seems to me this future bears a remarkable resemblance to the past, where people had to create their own products by raising their own food, spinning, weaving, and sewing their own clothes, etc. The Industrial Revolution changed all that and turned most folks into ‘wage slaves’. As I recall, that’s from Marx and it’s a description of a loss of personal agency/autonomy, i.e., being a slave to wages (no longer producing your own food, clothing, etc.) and not a reference to poor wages as many believe (including me until I got a somewhat snotty professor for one of my courses).

The podcast is definitely worth your time if you don’t mind the references to Marx (there aren’t many) as the ideas are provocative even if you don’t agree. Koepsell describes how his interest in this area was awakened (he wrote about software, which is both copyrightable as writing and patentable as a machine).

The book is available as a free download or you can purchase it here. Here’s a brief excerpt from the book’s introduction (I removed a citation number),

Science demands unfettered inquiry into the workings of nature, and replaces the confidence previously demanded over rote knowledge with a practiced skepticism, and ongoing investigation. With the rise of the age of science came the need to develop new means of treating information. Scientific investigations conducted by ‘natural philosophers’ could only be conducted in full view, out in the open, with results published in meetings of scientific societies and their journals. Supplanting secret-keeping and obscurantism, the full sunlight of public and peer scrutiny could begin to continually cleanse false assumptions and beliefs, and help to perfect theories about the workings of the world. Science demanded disclosure, where trades and arts often encouraged secrets. And so as natural philosophers began to disseminate the results of their investigations into nature, new forms of trade, art, and industry began to emerge, as well as the demand for new means of protection in the absence of secrecy. Thus, as the scientific age was dawning, and helping to fuel a new technological revolution, modern forms of IP [intellectual property] protection such as patents and copyrights emerged as states sought to encourage the development of the aesthetic and useful arts. By granting to authors and inventors a monopoly over the practice of their art, as long as they brought forth new and useful inventions (or for artistic works, as long as they were new), nation states helped to attract productive and inventive artisans and trades into their borders. These forms of state monopoly also enabled further centralization of trades and industries, as technologies now could become immune from the possibility of ‘reverse-engineering’ and competitors could be kept at bay by the force of law. This sort of state-sanctioned centralization and monopoly helped build the industrial revolution (by the account of many historians and economists, although this assumption has lately been challenged) as investors now could commodify new technologies free from the threat of direct competition, secure in the safe harbor of a state-supported monopoly over the practice of a useful art for a period of time.

In many ways, traditional IP [intellectual property] was (and is) deemed vital to the development of large industries and their infrastructures, and to the centralized, assembly-line factory mode of production that dominated the twentieth century. With the benefit of a state-sanctioned monopoly, industry could build sufficient infrastructure to dominate a market with a new technology for the duration of a patent. This confidence assured investors that there would be some period of return on the investment in which other potential competitors are held at bay, at least from practicing the art as claimed in the patent. Factories could be built, supply chains developed, and a market captured and profited from, and prices will not be subject to the ruthless dictates of supply and demand. Rather, because of the luxury of a protected market during the period of protection, innovators can inflate prices to not only recoup the costs of investment, but also profit as handsomely as the captive market will allow.

For most of the twentieth century, IP allowed the concentration of industrial production into the familiar factory, assembly-line model. Even while the knowledge behind new innovation moved eventually into the public domain as patents lapsed, during the course of the term of patent protection, strictly monopolized manufacturing processes and their products could be heavily capitalized, and substantial profits realized, before a technique or technology lost its protection. But the modes and methods of manufacturing are now changing, and the necessity of infrastructural investment is also being altered by the emergence of new means of production, including what we’ll call ‘micromanufacturing’, which is a transitional technology on the way to true MNT (molecular nanotechnology), and is included in our discussions of ‘nanowares’. Essentially, assembly-lines and supply chains that supported the huge monopolistic market dominance models of the industrial revolution, well into the twentieth century, are becoming obsolete. If innovation and production can be linked together with modern and futuristic breakthroughs in micromanufacturing (in which small components can be fabricated and produced en mass, cheaply) and eventually molecular manufacturing (in which items are built on the spot, from the ground up, molecule by molecule), then we should consider whether the IP regimes that helped fuel the industrial revolution are still necessary, or even whether they were ever necessary at all. Do they promote new forms of innovation and production, or might they instead stifle potentially revolutionary changes in our manners of creation and distribution?

Amusingly, towards the end of the interview Dr. J plugs Koepsell’s ‘nanotechnology’ book by noting it’s available for free downloads then saying ‘we’re hoping you’ll buy it’ (at the publisher’s site).