I’ve got two items: one from the University of Nottingham (UK) where they’re working on tissue regeneration for bones, muscles, and the heart.The second item is from Simon Fraser University (Vancouver, Canada)where the focus is on regenerating bones.
Here’s more about the work at the University of Nottingham from the [July 3, 2012] news item on Nanowerk,
The University of Nottingham has begun the search for a new class of injectable materials that will stimulate stem cells to regenerate damaged tissue in degenerative and age related disorders of the bone, muscle and heart.
The work, which is currently at the experimental stage, could lead to treatments for diseases that currently have no cure. The aim is to produce radical new treatments that will reduce the need for invasive surgery, optimise recovery and reduce the risk of undesirable scar tissue.
The research, which brings together expertise in The University of Nottingham’s Malaysia Campus (UNMC) and UK campus, is part of the Rational Bioactive Materials Design for Tissue Generation project (Biodesign). This €11m EU funded research project which involves 21 research teams from across Europe is made up of leading experts in degenerative disease and regenerative medicine.
The original July 3, 2012 news release from the University of Nottingham includes a video which offers some additional insight (sadly ,it cannot be embedded here) and more information (Note: I have removed a link),
Kevin Shakesheff, Professor of Advanced Drug Delivery and Tissue Engineering and Head of the School of Pharmacy, said: “This research heralds a step-change in approaches to tissue regeneration. Current biomaterials are poorly suited to the needs of tissue engineering and regenerative medicine. The aim of Biodesign is to develop new materials and medicines that will stimulate tissue regeneration rather than wait for the body to start the process itself. The aim is to fabricate advanced biomaterials that match the basic structure of each tissue so the cells can take over the recovery process themselves.”
The Canadian project at Simon Fraser University features a singular focus on bone regeneration, from the July 19, 2012 news release on EurekAlert,
A Simon Fraser University researcher is leading a team of scientists working to create new drugs to stimulate bone regeneration – research that will be furthered by a $2.5 million grant from the Canadian Institutes of Health Research (CIHR).
Lead researcher Robert Young heads a team of internationally recognized experts in bone disease and drug development. The researchers are focusing on developing small molecule compounds and nano-medicines that stimulate bone regeneration, and hope to identify new therapeutic approaches by improving understanding of bone renewal biology.
Their objective is to develop new therapeutic agents that promote bone repair, regeneration and renewal, and prove their efficiency in reproducing or improving bone strength.
The research involves studying the “natural controls” that guide the development of cells in the bones toward either bone forming or bone resorbing cells, setting the stage for the next generation of bone regenerative therapies.
The grant is one of three announced today by the federal government targeting bone health research and totalling $7 million. The others focus on wrist fractures management and identifying bone loss in gum disease.
The funding is through the CIHR’s Institute of Musculoskeletal Health and Arthritis and addresses priorities identified at a 2009 national Bone Health Consensus Conference.
I’ve decided to focus on tissues today so there will be something about tissue engineering and jellyfish (artificial) shortly.