Tag Archives: risk

Co-writing a symposium blurb about Risk, uncertainty and sustainable innovation

Co-writing may be a little bit of an exaggeration but Andrew Maynard over at his 2020 Science blog has asked for comments about a blurb he’s writing for a 2011 a symposium on Risk, Uncertainty and Sustainable Innovation being organized by the Risk Science center [at the University of Michigan] next September [2011]. Here’s an excerpt,

As technologies become more sophisticated, pressures on global resources grow and society becomes ever-more interconnected, governments, businesses and citizens are facing increasingly complex challenges as they strive to build an economically, socially and environmentally sustainable future. Over the past century, technology innovation has accelerated to the point where scientists and engineers have greater control over materials, organisms and systems – from the atomic scale to the planetary scale – that ever before. This has facilitated a radical shift in global communication, leading to an interconnected society where the flow of information, ideas and influence transcends geographical, economic and social boundaries. At the same time, a growing and increasingly plugged-in world population is placing unprecedented demands on ever-scarcer global resources.

The result is a world where innovation is both a driver of and a potential source of solutions to an increasing number of emerging global challenges.

You can go here to read all of it and comment.

Sunscreen and nano time, again (part 1)

Before launching into another discussion about the safety of sunscreens with titanium dioxide and/or zinc oxide nanoparticles, I’m going to mention uncertainty and risk. First, the notion of uncertainty that I”m using is proposed in a theory coined Knightian Uncertainty and comes from the field of economics. Here’s a definition from an article by Peter Dizikes at the Massachusetts Institute of Technology News Office,

Frank Knight was an idiosyncratic economist who formalized a distinction between risk and uncertainty in his 1921 book, Risk, Uncertainty, and Profit. As Knight saw it, an ever-changing world brings new opportunities for businesses to make profits, but also means we have imperfect knowledge of future events. Therefore, according to Knight, risk applies to situations where we do not know the outcome of a given situation, but can accurately measure the odds. Uncertainty, on the other hand, applies to situations where we cannot know all the information we need in order to set accurate odds in the first place.

Making a distinction between uncertainty and risk is very helpful in trying to understand some of the less pleasant possibilities of nanotechnology-enabled products. As more research about titanium dioxide and zinc oxide nanoparticles in sunscreens is published, there’s more information that can be used to assess risk.

With regard to health, two categories of risk are commonly discussed, absolute risk and relative risk. Here is a definition excerpted  from the Patient UK website,

Absolute risk of a disease is your risk of developing the disease over a time-period. We all have absolute risks of developing various diseases such as heart disease, cancer, stroke, etc. The same absolute risk can be expressed in different ways. For example, say you have a 1 in 10 risk of developing a certain disease in your life. This can also be said a 10% risk, or a 0.1 risk – depending if you use percentages or decimals.

Relative risk is used to compare the risk in two different groups of people. For example, the groups could be ‘smokers’ and ‘non-smokers’. All sorts of groups are compared to others in medical research to see if belonging to a group increases or decreases your risk of developing certain diseases. For example, research has shown that smokers have a higher risk of developing heart disease compared to (relative to) non-smokers.

In these scenarios (heart diseases and smoking vs. non-smoking) there’s enough information to make an informed guess even though a degree of uncertainty still exists. By contrast, the situation with nanosunscreens doesn’t lend itself to an analysis of absolute or relative risk as basic information is still being gathered.

Meanwhile the civil society/activist group, Friends of the Earth (FOE) has renewed their call to remove sunscreens with titanium dioxide and/or zinc oxide nanoparticles from the market. Andrew Maynard at 2020 Science has very carefully analysed the six studies that FOE has published on their nanosunscreen page. From Andrew’s posting,

As these are evidence-based statements, I thought it would be worth while going through them, and taking a look at the evidence they are based on:

FoE: “Manufactured nanomaterials used in sunscreens (such as zinc oxide and titanium oxide) can Damage human colon cells: A study from the University of Utah showed that nano zinc oxide is toxic to colon cells even in small amounts. The scientists called for more research and warned that the evidence is especially concerning for children who are more likely to accidently ingest sunscreen. The colon is vital because it eliminates food waste and absorbs important nutrients.”

This was a study that looked at interactions between zinc oxide (ZnO) particles and cells derived from the human colon, and was carried out in vitro (i.e. in a cell culture rather than in animals or people). It did indeed indicate that nanometer scale ZnO particles were around twice as potent as larger ZnO particles in their ability to kill these cells under idealized conditions. But the research also emphasized that direct contact with the cells was needed for a nanoscale particle-related effect. In fact, the title of the paper was “ZnO Particulate Matter Requires Cell Contact for Toxicity in Human Colon Cancer Cells,” emphasizing this point above the higher potency of the more finely structured particles.

The research was interesting, but did not resolve whether zinc oxide particles could survive long enough in the gut to come into contact with cells lining the colon, whether interactions like those observed in the laboratory are plausible under real-world conditions, and what levels of exposure would be needed to cause significant harm. The research also indicated that larger particles of zinc oxide – similar to particles that have been used in sunscreens and other topical creams for decades – were toxic to cells under the conditions of the study.

So regular and nanosized particles of zinc oxide are both toxic to colon cells with the nanosized particles being 2 x more toxic. That’s not great but we’ve been using regular sized zinc oxide particles  for quite some time and, as far as I know, no one claims that it causes colon cancer.  Also, these tests were conducted with cultures (i. e. not inside the human or any other type of body) so there’s no proof that zinc oxide of any size survives long enough to enter the colon. If there were an absolute risk associated with using regular sized zinc oxide particles, theoretically we could infer an absolute risk for nanosized zinc oxide particles.

More later today.

Site remediation and nano materials; perspectives on risk assessment; Leonardo’s call for nano and art; a new nano art/science book

The Project on Emerging Nanotechnologies (PEN) is holding an event on site remediation on Feb. 4, 2010 (12:30 pm to 1:30 pm EST). From the news release,

A new review article appearing in Environmental Health Perspectives (EHP) co-authored by Dr. Todd Kuiken, Research Associate for the Project on Emerging Nanotechnologies (PEN), Dr. Barbara Karn, Office of Research and Development, U.S. Environmental Protection Agency and Marti Otto, Office of Superfund Remediation and Technology Innovation, U.S. Environmental Protection Agency focuses on the use of nanomaterials for environmental cleanup. It provides an overview of current practices; research findings; societal issues; potential environment, health, and safety implications; and possible future directions for nanoremediation. The authors conclude that the technology could be an effective and economically viable alternative for some current site cleanup practices, but potential risks remain poorly understood.

PEN’s Contaminated Site Remediation: Are Nanomaterials the Answer? features the EHN article’s authors  Kulken, Karn, and Otto on a panel with David Rejeski, PEN’s executive director moderating. PEN also has a map detailing almost 60 sites (mostly in the US, 2  in Canada, 4 in Europe, and 1 in Taiwan) where nanomaterials are being used for remediation.  More from the news release,

According to Dr. Kuiken, “Despite the potentially high performance and low cost of nanoremediation, more research is needed to understand and prevent any potential adverse environmental impacts, particularly studies on full-scale ecosystem-wide impacts. To date, little research has been done.”

In its 2004 report Nanoscience and nanotechnologies: opportunities and uncertainties, the British Royal Society and Royal Academy of Engineering recommended that the use of free manufactured nanoparticles be prohibited for environmental applications such as remediation until further research on potential risks and benefits had been conducted. The European Commission’s Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) called for further risk research in 2005 while acknowledging environmental remediation technology as one of nanotechnology’s potential benefits.

If you wish to attend in person (i.e. you are in Washington, DC), you are asked to RSVP here (they provide a light lunch starting at 12 pm) or you can watch the webcast (no RSVP necessary and I will put up a link to the webcast closer to the date).

On the topic of risk, Michael Berger has written an in depth piece about a recently published article, Redefining research risk priorities for nanomaterials, in the Journal of Nanoparticle Research. From Berger’s piece,

While research in quantitative risk characterization of nanomaterials is crucially important, and no one advocates abandoning this approach, scientists and policy makers must face the reality that many of these knowledge gaps cannot be expected to be closed for many years to come – and decision making will need to continue under conditions of uncertainty. At the same time, current chemical-based research efforts are mainly directed at establishing toxicological and ecotoxicological and exposure data for nanomaterials, with comparatively little research undertaken on the tools or approaches that may facilitate near-term decisions.

In other words, there’s a big lag between developing new products using nanomaterials and the research needed to determine the health and environmental risks associated both with the production and use of these new materials. The precautionary principle suggests that we not produce or adopt these products until we are certain about risks and how to ameliorate and/or eliminate them. That’s an impossible position as we can never anticipate with any certainty what will happen when something is released to the general public or into the environment at large.  From Berger’s piece,

In their article, [Khara Deanna] Grieger [PhD student at Technical University of Denmark (DTU)], Anders Baun, who heads DTU’s Department of Environmental Engineering, and Richard Owens from the Policy Studies Institute in the UK, argue that there has not yet been a significant amount of attention dedicated to the field of timely and informed decision making for near term decisions. “We see this as the central issue for the responsible emergence of nanotechnologies” says Grieger.

Getting back to site remediation using nanomaterials, since it’s already in use as per the map and the authors state that there hasn’t been enough research into risks, do we pull back and adopt the precautionary principle or do we proceed as intelligently as possible in an area where uncertainty rules? That’s a question I will continue to explore as I get my hands on more information.

On a completely different nano front, the Leonardo magazine has issued a call for papers on nano and art,

2011 is the International Year of Chemistry! To celebrate Leonardo is seeking to publish papers and artworks on the intersections of chemistry,
nanotechnology and art for our on-going special section on nanotechnology and the arts. Since its inception nanotech/science has been intimately connected to chemistry; fullerenes, nanoputians, molecular machines, nano-inorganics and self-assembling molecular systems all spring from the minds and labs of chemists, biochemists and chemical engineers. If you’re a nano-oriented chemist who is serious about art, an artist working on the molecular level, or a chemical educator exploring the mysteries of nano through the arts we are especially seeking submissions from you.

You can send proposals, queries, and/or manuscripts to the Leonardo editorial office: leonardomanuscripts@gmail.com. You can read more about the call for papers here at Leblogducorps or you can go here to the Leonardo online journal.

Meanwhile, Andrew Maynard at 2020 Science is posting about a new book which integrates art work in an attempt to explain nanotechnology without ever mentioning it. From Andrew’s posting,

How do you write a book about something few people have heard off, and less seem interested in?  The answer, it seems, is to write about something else.

Felice Frankel and George Whitesides have clearly taken this lesson to heart. Judged by the cover alone, their new book “No Small Matter:  Science at the Nanoscale” is all about science in the Twilight zone of the nanoscale

– where stuff doesn’t behave in the way intuition says it should.

Drat! I can’t make the indent go away. At any rate, do visit 2020 as Andrew to read more from this posting and at least one other where he has gotten permission to excerpt parts of the book (text and images).

Quick peek at nanotechnologies and food report from UK House of Lords

After getting  an advance copy of the new report from the UK’s House of Lords Science, Technology and Industry Committee (mentioned in my post of Jan.5.10), I spent a good chunk of the day reading it. These are fast impressions:

  • it seemed quite thorough relative to the scope of the investigation and from the perspective of a Canadian who hasn’t seen her own government investigate and make public information about the state of any nanotechnology research, I found this to be quite refreshing
  • there was something strange about the benefits and that strangeness was the focus on obesity and waste…much else is mentioned but obesity and waste (i.e. reducing both) are strongly emphasized as possible areas where benefits could be experienced.
  • secrecy on the part of the food industry’s nanotechnology research was noted and discussed at length with an analysis that was both sympathetic to the industry’s concerns (i.e. that there would be a replay of the GM and food irradiation controversies and/or competition would be inhibited) and adamant that adopting secrecy as a strategy is wrong-minded.
  • nanotechnology research in the UK is coordinated through a single agency (I believe that’s true in the US as well but it’s definitely not the case in Canada).
  • they were quite critical of the current toxicology research efforts, irrespective of nanotechnology, there aren’t enough toxicology researchers in the UK as well there’s a specific problem with the nanotoxicology, i.e. knowledge gaps (from the report [and they are quoting from a previous report], pp. 34-5 ),

EMERGNANO report states that “this review of ongoing studies has failed to demonstrate that there is any comprehensive attempt to gain the toxicokinetic … data required to reach the aims of hazard identification” and there have been “no systematic studies on the potential of different kinds of nanoparticles to get into the blood, the lymph or the brain”. We find this conclusion worrying.

We are disappointed and concerned that the Research Councils have not adopted a more pro-active approach to encourage and stimulate research bids in areas where existing mechanisms have so far proved ineffective. Dr Mulkeen told us that the MRC would take “more active steps if needed” to develop research into the safety of nanotechnologies (Q 420). We feel that a more pro-active stance is essential given the lack of progress in several key areas to date.

  • some of the difficulty re: nanotoxicology research seems to be attributable to the funding structure (from the report p. 35),

The 2007 review by the CST concluded that the primary reason for the Government’s slow progress on health and safety research was due “to an over-reliance by Government on responsive mode funding, rather than on directed programmes by Government departments to deliver the necessary research”.44 A number of witnesses supported this view. Professor Donaldson, for example, told us: “If we look at the Royal Academy/Royal Society report, there was a really important paragraph that there should be a central core-funded chunk of research and expertise brought together to design a programme that would look systematically at nanoparticle toxicology, and that was ignored. We had response mode funding where people just put forward what they wanted to do, so what you get is piecemeal” (Q 267).
Professor Jones also alluded to the relative strength of research investigating nanoparticle toxicology in the lung compared to a lack of research into the
gut as a result of response-mode funding (Q 494).

  • there is a huge difference between the funds for nanotechnology research (one agency spent 220 million pounds on nanotech research over a 5 year period) and funds for nanotoxicology research (less than 600,000 pounds per annum or less than 3 million pounds in a five year period) which I imagine is much  the same elsewhere.
  • they do mention Canada as a country that has announced a mandatory register of nanomaterials which will include information on safety data (this register has been referred to in other reports but no one ever cites a source and I’ve never been able to confirm that this register is actually being developed).
  • in their recommendations for regulatory enforcement they seemed to be reinforcing the status quo or bringing the UK into line with current European Union practices.
  • in the last bit they discuss communication, i.e. there should be yet another survey of public attitudes although this will be about nanotechnologies and food, they acknowledge the government’s decision to create a new website on the subject, they’d like it if the government would work with the industry folks to become more open about their research, there won’t be blanket labelling of nanotechnology on  food products, and they think public engagement should be undertaken.

The last two bits, regulation and communication, are the least developed sections of the report. I found that overall there was a good balance between sympathy for industry interests and concern for health issues. Some of the strongest language in the report was used in the sections on nanotoxicology and its lack of research.

Industrial production of carbon nanotubes?; Portland Art Museum’s China exhibit; scientific business not a good idea

We hear a lot of hype about all the new products and materials that nanotechnology will make possible for us but it’s always at some unspecified future date or  something like ‘it will come to market in three to five years or, five to seven years’.  I’m still waiting for self-cleaning windows which, as far as I know, no one has promised to bring market at any time (sigh). There is a ray of light regarding new carbon nanotube-based materials according to an article by Michael Berger on Nanowerk. From the article,

For years now, nanotechnology researchers have been promising us carbon nanotubes as the basis for numerous breakthrough applications such as multifunctional high-strength fibres, coatings and transparent conducting films. Not to mention as a cure for cancer (see “Horeradish, carbon nanotubes and cancer therapy”) and a solution to the energy crisis. … CNTs are notoriously difficult to work with and, because researchers haven’t found efficient ways yet to assemble them, the resulting materials demonstrate only a small fraction of the possible single-object properties of CNTs. …

New research reported this week has now established an industrially relevant process for assembling carbon nanotubes that allows them to efficiently be made into fibers, coatings and films – the basic forms of material that can be used in engineering applications.

With the possibility of producing carbon nanotubes on a large scale, I would imagine some folks will be curious about health & safety and environmental issues. On occasion I’ve included information about research on carbon nanotubes and their resemblance to asbestos fibres. These carbon nanotubes are multi-walled carbon nanotubes (MWCNT) and the ones being made ready for industrial purposes in Berger’s article are single-walled CNTs. I have not come across anything yet which suggests that single-walled CNTs resemble asbestos fibres.

Back to China. The Portland (Oregon) Art Museum has a major exhibit called China Design Now according to an article by Steve McCallion, The Portland Art Museum Transforms an Art Exhibition into a Social Platform, in Fast Company. From the article,

As I mentioned in previous posts, the Portland Art Museum brought China Design Now, the London Victoria & Albert exhibit, to Portland to attract a new audience and elevate Portland’s cultural discourse to a global level. The exhibition documents China’s impressive advancement in graphics, fashion and design over the last 20 years. In my last post  I discussed how the Portland Art Museum used story and metaphor to make the exhibition even more meaningful. The museum’s most significant innovation, however, is not in the content of the exhibition–it’s the museum experience itself.

I’m very enthused about this and would dearly love to get to Portland to experience the various shows, that’s right plural–shows not show. The museum folks encouraged artists and people working in galleries to put on their own shows as part of a larger dialog for Portland. The art museum also extended itself online,

To extend community involvement online, the museum created CDNPDX.org where sixteen different blog editors from the community contribute content and editorial perspectives daily. They are not museum employees, but people from the community that have insight into China and/or design, and are willing to contribute to the discourse for free.

While including potentially offensive underground comics and “amateur” art may make some traditional museum-goers uncomfortable, the museum believes that inviting people to be part of the experience is necessary to remain relevant and worth the risk.

Meanwhile at the Vancouver Art Gallery, we continue with the traditional art museum experience (sigh).

Following my concerns about introducing scientific methods into government bureaucracies, I found this somewhat related article by Linda Tischler (in Fast Company) about scientific methods in business. From the article, a portion of the interview with Roger Martin, Dean of the Rotman School of Management at the University of Toronto,

Martin: Well, yes. With every good thing in life, there’s often a dark shadow. The march of science is good, and corporations are being run more scientifically. But what they analyze is the past. And if the future is not exactly like the past, or there are things happening that are hard to measure scientifically, they get ignored. Corporations are pushing analytical thinking so far that it’s become unproductive. The future has no legitimacy for analytical thinkers.

Fast Company: What’s the alternative?

Martin: New ideas must come from a new kind of thinking. The American pragmatist Charles Sanders Peirce called it abductive logic. It’s a logical leap of the mind that you can’t prove from past data.

Fast Company: I can’t see many CEOs being comfortable with that!

Martin: Why not? The scientific method starts with a hypothesis. It’s often what happens in the shower or when an apple hits you on the head. It’s what we call ‘intuitive thinking.’ Its purpose is to know without explicit reasoning.

I’m relieved to see that Martin points out that scientific thinking does require creativity but his point that things which are hard to measure scientifically get ignored is well taken. While scientific breakthroughs often arise from a creative leap, the work (using the scientific method) to achieve that leap is painstaking and the narratives within the field tend to ignore the creative element. This is almost the opposite of an artistic or creative endeavour which also requires a creative leap and painstaking work to achieve but where narrative focuses primarily on the creative.

The scientific method for many is considered to be  rigorously objective and inspires a certain faith (at times, religious in its intensity). It is a tool and a very effective tool in some, not all, situations. After all, you use a hammer ti build something with a nail, you don’t use it to paint your walls.

As for the Thomson Reuters report on China, I tried but had no joy when trying to retrieve it.

Canadian science policy conference has started; silver nanoparticles wash off your antibacterial socks

Rob Annan is reporting from the science policy conference taking place in Torontp, Oct. 28-30, 2009. (More info. about the conference here and Rob’s blog here with his comments and links to other commentaries.) From the 2nd keynote speaker’s (Bruce Alberts, scientist and editor-in-chief of Science magazine) speech as Rob reports,

“If you want your government interested in science and technology, send them to China”, he [Alberts] quipped. He pointed out that the Chinese Minister of Health, Chen Zhu, is a world-renowned molecular biologist who is reshaping his country’s health ministry and is employing many of the tools that served him well as a scientist. Alberts suggested that China’s embrace of science and its methods, the number of scientists and engineers in top roles in the Chinese government, and the role science is playing in the emerging Chinese economy, can’t help but convince other countries of its benefits – I’m [Rob Annan] not so sure…

Alberts also argued that to spread science in society, you need to spread scientists. Too few trained scientists – at the PhD level, he argued – enter other areas of society. Only by having trained scientists working as lawyers, journalists, and – especially – in government, can we expect science to play a broader role in society at large.

Alberts seems a bit fevered. I don’t disagree with the principle that it’s a good idea to have people with grounding in both sciences and other specialties. However, there does seem to be an underlying assumption about science and scientists and to make my point I’m going to flip his suggestion. Have the English majors, the social workers, the musicians, the lawyers, etc. take up science so that  society has more of a role in science. I don’t have time today to finish this but I will get back to it tomorrow.

Swiss scientists have published a study about silver nanoparticles being washed off in the laundry. There is a news item here or here.

Nanotechnology, risk, science literacy and feelings; Canada’s Science and Technology Week 2009

The Swiss-based Innovation Society has waded into the discussion about nanoparticles and sunscreens  in the wake of the Friends of the Earth (FOE) report (mentioned here yesterday August 20, 2009).

They point out something I forgot. Despite disagreeing on the “risk  profile,” both the Environmental Working Group (EWG) and FOE advise that nanomaterials should be labelled so that consumers can make informed choices,  (I’m not sure if I’ve seen the phrase risk profile or if I just coined it but I hope it makes sense in this context.) You can read about the Innovation Society’s perspective in their media release on Nanowerk News where they also offer links to the society’s August 2009 newsletter. You have to register to receive it and the form is in German as is the page which houses the public portion of the August 2009 newsletter. So, I’m not sure what language the newsletter is written in although most of what I saw on their site is in English.

As this last week has featured a published study about two women workers who died due to nanoparticle exposure and the FOE report, I’ve been reminded of the Cultural Cognition Project at Yale Law School (mentioned here on this blog last week). One of the conclusions in the paper I read about nanotechnology and risk is that people will make judgments about emerging technologies quickly, with little information, and in line with their feelings (affect), and cultural values. In the experimental investigation they found that increasing scientific literacy (i.e. giving the respondents more factual information about nanotechnology) did nothing or very little to alter someone’s opinion once it was formed.

I can agree with this conclusion as far as it goes. I’ve observed the same process of adhering to an opinion despite any evidence to the contrary in myself and others. I noted yesterday that the FOE report did not mention the EWG findings which, in my opinion, damages their credibility and bears out the conclusions made by the team at the Cultural Cognition Project.

There is one thing which niggles at me. Technologies have emerged before, e.g. electricity. At the time, during the 19th century, it was highly contested (do take a look at Carolyn Marvin’s book, When Old Technologies were New) . Very inflammatory language was used; all kinds of “experts” emerged; scientists engaged in lots of public outreach; there were deaths and injuries; and there were predictions that life on earth would end.  Seems familiar, doesn’t it? Still, electricity has become ubiquitous for much of the world. If cultural values and feelings trump science literacy, how did electricity become ubiquitous?

The Cultural Cognition Project team seemed to suggest in their paper that once opinions have been formed they are largely intractable. If that’s so, regardless of which group’s narrative gains dominance wouldn’t the other group continue to resist? (Note: the Amish opted out from using electricity.) History tells us otherwise.

I am getting ready for my presentation at the International Symposium on Electronic Arts (ISEA) so y9u may find that my posting schedule is interrupted. Happy weekend and here are a few final nuggets,

The Government of Canada, in the person of Rona Ambrose, Minister of Labour, has recognized Quantium Technologies (Edmonton, Alberta) for its innovation in the areas of “linking scientific research to commercialization, jobs and economic growth.” More can be found  in the media release on Nanowerk News.

Nanowerk News has also published a guide to the materials on their site, 10 things you should know about nanotechology. I highly recommend checking this out. Go here.

Canada’s 2009 Science and Technology Week will take place Oct. 16 – 25, 2009 (seems more like 10 days to me). You can check out the currently scheduled events (I’m sure this will be updated) for your province here,

There’s an interesting  story about the first copyright trial in 6th Century Ireland here on Techdirt.

Friends of the Earth and sunscreens; update on RUSNANO

In a bit of interesting timing given that it’s on the heels of the publication of a study about two tragic deaths which are being attributed to exposure to nanoparticles, the Friends of the Earth (FOE) organization has released a report titled Nano-Sunscreens: Not Worth the Risk.The media release can be found on Azonano or Nanowerk News.

I have read the report (very quickly) and noted that they do not cite or mention the recently released report on the same topic by the Environmental Working Group (EWG) which stated that after an extensive review of the literature, there was no evidence that the titanium dioxide or zinc oxide nanoparticles used in sunscreens were dangerous. (posting here).

Shortly after the EWG report’s release, a new study (which I mentioned here … if you are inclined, do read the comments as some additional points about reading research critically are brought out)  suggested concerns based on the work of researchers in Japan.  The new study from Japan is cited in the Friends of the Earth report.

While the overall tone of the FOE report is fairly mild (they suggest precaution) they cite only a few studies supporting their concern and they damage their credibility (in my book) by ignoring a report from a well respected group that reluctantly admitted that there is no real cause for concern about nanoparticles in sunscreens based on the current evidence. FOE didn’t have to agree with the EWG’s conclusions but some counter-argument or discussion suggests that they don’t have a counter-argument or that they will ignore any opinions, and in the EWG case it’s based on evidence, contrary to their own.

More about this tomorrow when I tie it into science literacy, critical thinking, affect (feelings), and values.

Meanwhile, RUSNANO (Russian Corporation of Nanotechnologies) has announced $1.25B US  (40billion rubles) of investment will be approved this year. I blogged (here) about RUSNANO when their executives visited Canada with an eye to investing in Canadian nanotechnology companies. I will be eagerly waiting to find out if RUSNANO has followed up with investments in Canadian nanotechnology.

More titanium dioxide news; the 5th anniversary of the Royal Society’s Report on Nanotechnology; Copyright in Canada

While titanium dioxide particles in sunscreens are considered safe (see my blog posting here), there is a new study which suggests concerns. A study was done in Japan on pregnant mice who were injected with titanium dioxide nanoparticles. The results suggest that the particles affected brain development in the foetuses. (The media release is located at Nanowerk News here.) My questions since I haven’t looked at the study are this:  Where was the injection site? What was the concentration of  titanium dioxide nanoparticles in the solution? Where several concentrations used or only one? (After all, a lot of medicines are poison if taken in the wrong dosage or misapplied [taken internally instead of externally].)

Still on the titanium dioxide trail, there’s a study by researchers in Switzerland which suggests that nanowires and nanotubes made of titanium dixoide are toxic. There’s an article by Miichael Berger here on Nanowerks. From Berger’s article,

One of the complications of nanotoxicology is that the toxicity of a specific nanomaterial cannot be predicted from the toxicity of the same material in a different form.

“TiO2 nanoparticles are widely used as UV blockers in sunscreens” says Arnaud Magrez [researcher]. “Their cytotoxicity has been tested before and they were found to be rather non-toxic. Our new study shows that TiO2 based nanofilaments, however, can be quite toxic. The geometry of nanoparticles appears to play a crucial role in cytotoxicity. Furthermore, the toxicity can be enhanced by the presence of defects on the nanofilament surface, resulting from chemical treatment.”

Both of these studies highlight why more research needs to be done. A comment which is made in an entirely different context by Dr. Andrew Maynard in his essay commemorating the anniversary of the Royal Society/Royal Academy of Engineering 2004 report on nanotechnologies. Maynard’s essay is the foreword to a report, 5 years on – a beacon or just a landmark? Reflections on the 2004  Royal Society/Royal Academy of Engineering report into nanotechnologies – what was its impact and what is its legacy? published by the Responsible Nano Forum. Maynard’s essay can be read here on his 2020 Science blog and the report can be found here. From Maynard’s essay,

At the time, concerns were mounting over possible new risks associated with creating materials and devices at the nanoscale, and how these would affect the technology’s development.  The previous year, Michael Crichton’s book Prey had sent the nanotech community into a tizzy over a speculative public backlash against the emerging science and technology.  And researchers were beginning to reveal hints that novel nanoscale materials could also affect humans and the environment in unconventional ways—getting to places and causing harm on a scale that belied their small size.

Do read it if you have the time. Maynard’s perspective is both historical and contemporary.

And now for something which concerns me when writing this blog, copyright. Since this blog isn’t profitmaking and I give attribution and encourage people to visit the sites and blogs I quote from, I’ve considered what I do ‘fair use’. If you’ve been following the copyright discussion, you know ‘fair use’ is being debated fiercely as is intellectual property law which includes copyright, patents, and trademarks.

After a rather disastrous attempt to introduce new copyright legislation (last fall I think), the Canadian government has launched a public consultation process. (I too was surprised to find out about it.) The roundtable meeting in Vancouver took place about 10 days ago. There will be roundtable meetings  elsewhere and two town hall meetings (where the public will be invited). If you’re a member of the public who’s lucky enough to live in either Toronto or Montreal, you can have your say in real time. The rest of us can participate online here at the Copyright Counsultations website. You do have to register to participate. The Vancouver roundtable meeting has been transcribed and is available online here and the trasncript for the Calgary roundtable is here.