Tag Archives: Trinity College Dublin

2.5M Euros for Ireland’s John Boland and his memristive nanowires

The announcement makes no mention of the memristor or neuromorphic engineering but those are the areas in which  John Boland works and the reason for his 2.5M Euro research award. From the Ap. 3, 2013 news item on Nanowerk,

Professor John Boland, Director of CRANN, the SFI-funded [Science Foundation of Ireland] nanoscience institute based at Trinity College Dublin, and a Professor in the School of Chemistry has been awarded a €2.5 million research grant by the European Research Council (ERC). This is the second only Advanced ERC grant ever awarded in Physical Sciences in Ireland.

The Award will see Professor Boland and his team continue world-leading research into how nanowire networks can lead to a range of smart materials, sensors and digital memory applications. The research could result in computer networks that mimic the functions of the human brain and vastly improve on current computer capabilities such as facial recognition.

The University of Dublin’s Trinity College CRANN (Centre for Research on Adaptive Nanostructures and Nanodevices) April 3, 2013 news release, which originated the news item,  provides details about Boland’s proposed nanowire network,

Nanowires are spaghetti like structures, made of materials such as copper or silicon. They are just a few atoms thick and can be readily engineered into tangled networks of nanowires. Researchers worldwide are investigating the possibility that nanowires hold the future of energy production (solar cells) and could deliver the next generation of computers.

Professor Boland has discovered that exposing a random network of nanowires to stimuli like electricity, light and chemicals, generates chemical reaction at the junctions where the nanowires cross. By controlling the stimuli, it is possible to harness these reactions to manipulate the connectivity within the network. This could eventually allow computations that mimic the functions of the nerves in the human brain – particularly the development of associative memory functions which could lead to significant advances in areas such as facial recognition.

Commenting Professor John Boland said, “This funding from the European Research Council allows me to continue my work to deliver the next generation of computing, which differs from the traditional digital approach.  The human brain is neurologically advanced and exploits connectivity that is controlled by electrical and chemical signals. My research will create nanowire networks that have the potential to mimic aspects of the neurological functions of the human brain, which may revolutionise the performance of current day computers.   It could be truly ground-breaking.”

It’s only in the news release’s accompanying video that the memristor and neuromorphic engineering are mentioned,

I have written many times about the memristor, most recently in a Feb. 26, 2013 posting titled, How to use a memristor to create an artificial brain, where I noted a proposed ‘blueprint’ for an artificial brain. A contested concept, the memristor has attracted critical commentary as noted in a Mar. 19, 2013 comment added to the ‘blueprint’  post,

A Sceptic says:

….

Before talking about blueprints, one has to consider that the dynamic state equations describing so-called non-volatile memristors are in conflict with fundamentals of physics. These problems are discussed in:

“Fundamental Issues and Problems in the Realization of Memristors” by P. Meuffels and R. Soni (http://arxiv.org/abs/1207.7319)

“On the physical properties of memristive, memcapacitive, and meminductive systems” by M. Di Ventra and Y. V. Pershin (http://arxiv.org/abs/1302.7063)

Namdiatream; a European multimodal diagnostics project

I’ve written about lab-on-a-chip projects, point-of-care diagnostics, and other such initiatives on several occasions, most recently in a Mar. 1, 2013 posting about a technique where powder is used to make the diagnostic device more portable. This time it was a Europe-wide project described in a Mar. 4, 2013 news item on Nanowerk,which caught my attention (Note: A link has been removed),

The plan of the EU-funded consortium Nanotechnological toolkits for multi-modal disease diagnostics and treatment monitoring (Namdiatream) is not to cure cancer, per se, but to boost the sensitivity of diagnostics and the ability to monitor progress during treatment. They focused on three types – breast, prostate and lung cancer.

… The prototype devices being developed during the four-year project will detect common cancer cells much earlier and, with timely treatment, improve the chances of recovery.

According to the project leader, Professor Yuri Volkov of Trinity College Dublin’s School of Medicine, the portable nanodevices are based on innovative lab-on-a-chip, -bead and -wire technologies applicable in different settings – clinical, research, or point of care (i.e. hospitals). These lab-on-x technologies exploit the photo-luminescent (‘glow-in-the-dark’ light emitting), plasmonic (‘light-on-a-wire’), magnetic and unique optical properties of nanomaterials.

Volkov offers some insight into how the project started and its current state of evolution (from the news item),

This is ground-breaking work made possible thanks to advanced technology but also to EU funding for cross-border investigations. Teams across Europe were doing related but fragmented research, suggests Prof. Volkov. This risked leaving a team dangling if their approach failed or lacked funding.

“So we integrated our research and identified joint strengths to help one another develop the best technological approaches in case something didn’t work in one, or synergies were identified, thereby increasing the chances of wider success.”

At its half-way stage, notes Prof. Volkov, Namdiatream underwent a natural evolution when it became clear that by merging and refocusing work in some areas – i.e. in fluorescent nanomaterial technology and magnetic nanowire barcodes – it would speed up industrial implementation efforts.

“Now, work on the preclinical prototype devices is well under way,” he confirms. But one of the many remaining challenges is to calibrate their sensitivity, so that they do not give false readings, for instance.

The Namdiatream (Nanotechnological Toolkits for Multi-Modal Disease Diagnostics and Treatment Monitoring) home page offers more detail about the project,

Namdiatream is a truly interdisciplinary and Pan-european consortium that builds around 7 High-Tech SMEs [small to medium enterprises], 2 Multinational industries and 13 academic institutions. NAMDIATREAM will develop nanotechnology-based toolkit to enable early detection and imaging of molecular biomarkers of the most common cancer types and of cancer metastases, as well as permitting the identification of cells indicative of early-stage disease onset. The project is built on the innovative technology concepts of super-sensitive “lab-on-a-bead”, “lab-on-a-chip” and “lab-on-a-wire” nano-devices.

Interestingly, this too was on the home page,

The ETP Nanomedicine documents point out that nanotechnology has yet to deliver practical solutions for the patients and clinicians in their struggle against common, socially and economically important diseases such as cancer. Therefore NAMDIATREAM results will firstly aim to deliver to the diagnostic and medical imaging device companies involved in the consortium, and the clinical and academic partners. This could further provide the basis for cancer therapeutics as it will be possible to accurately assess the kinetics of cancer cell destruction during the course of appropriate therapy.

My carbon nanotube heart and patents

The stem cell scientists at the National University of Ireland (NUI) and Trinity College Dublin’s CRANN (Centre for Research on Adaptive Nanostructures and Nanodevices) aren’t making hearts out of carbon nanotubes but they are using the particles to stimulate stem cells into becoming heart-like.The Sept. 19, 2012 news item on Nanowerk provides context for this work,

Stem cell scientists have capitalised on the electrical properties of a widely used nanomaterial to develop cells which may allow the regeneration of cardiac cells. The breakthrough has been led by a team of scientists at the Regenerative Medicine Institute (REMEDI) at the National University of Ireland Galway in conjunction with Trinity College Dublin.

Heart disease is the leading cause of death in Ireland. Once damaged by heart attack, cardiac muscle has very little capacity for self-repair and at present there are no clinical treatments available to repair damaged cardiac muscle tissue.

Over the last 10 years, there has been tremendous interest in developing a cell-based therapy to address this problem. Since the use of a patient’s own heart cells is not a viable clinical option, many researchers are working to try to find an alternative source of cells that could be used for cardiac tissue repair.

The NUI Sept. 19, 2012 news release, which originated the news item, describes how carbon nanotubes have properties similar to certain heart cells and how the researchers decided to exploit that similarity,

The researchers recognised that carbon nanotubes, a widely used nanoparticle, is reactive to electrical stimulation. They then used these nanomaterials to create cells with the characteristics of cardiac progenitors, a special type of cell found in the heart, from adult stem cells.

“The electrical properties of the nanomaterial triggered a response in the mesenchymal (adult) stem cells, which we sourced from human bone marrow. In effect, they became electrified, which made them morph into more cardiac-like cells”, explains Valerie Barron of REMEDI at National University of Ireland Galway. “This is a totally new approach and provides a ready-source of tailored cells, which have the potential to be used as a new clinical therapy. Excitingly, this symbiotic strategy lays the foundation stone for other electroactive tissue repair applications, and can be readily exploited for other clinically challenging areas such as in the brain and the spinal cord.”

The team’s collaborator at CRANN, Professor Werner Blau made a comment I found a bit odd (from the NUI news release),

“It is great to see two decades of our pioneering nanocarbon research here at TCD come to fruition in a way that addresses a major global health problem. Hopefully many people around the world will ultimately benefit from it. Some of our carbon nanotube research has been patented by TCD and is being licensed to international companies in material science, electronics and health care,” said Professor Blau.

I’m not a big fan of the current patenting regimes which seem to  have been turned  into innovation-killing machines.  As for patenting medicines and medical devices, I recall that Frederick Banting and Charles Best who discovered insulin refused to patent the discovery as they believed it would constrain access.

I appreciate that businesses need to make money and scientists need money to do their work and so on but this blind rush to patent discoveries seems a little misguided to me and it might be a good time to consider new business and economic models.

Better beer in plastic bottles

This innovation in beer bottling was developed in Ireland and I’m pretty sure the Irish have themselves braced for the humourous comments sure to follow given the legends about the Irish and beer.

Here’s more about the nanotechnology-enabled plastic beer bottles from the Sept. 18, 2012 news item on Nanowerk,

Scientists at CRANN [Centre for Research on Adaptive Nanostructures and Nanodevices], the Science Foundation Ireland-funded nanoscience institute based at Trinity College Dublin, have partnered with world-leading brewing company SABMiller on a project to increase the shelf life of bottled beer in plastic bottles. The new deal will see SABMiller invest in the project over a two year period.

Professor Jonathan Coleman and his team in CRANN are using nanoscience research methods to develop a new material that will prolong the shelf-life of beer in plastic bottles. Current plastic bottles have a relatively short shelf life, as both oxygen and carbon dioxide can permeate the plastic and diminish the flavour.

The new material, when added to plastic bottles will make them extremely impervious, meaning that oxygen cannot enter and that the carbon dioxide cannot escape, thus preserving the taste and ‘fizz’.

The Sept. 18, 2012 CRANN news release does not include many more details about the technology,

The team will exfoliate nano-sheets of boron nitride, each with a thickness of approximately 50,000 times thinner than one human hair. These nano-sheets will be mixed with plastic, which will result in a material that is extremely impervious to gas molecules. The molecules will be unable to diffuse through the material and shelf life will be increased.

As well as increasing the shelf life of the beer itself, less material is required in production, reducing cost and environmental impact.

If you are lucky enough to have a subscription or have some other access to Science magazine, you can read more about Coleman’s and his team’s work on boron nitride and thin films. Here’s the citation and abstract for the article,

Two-Dimensional Nanosheets Produced by Liquid Exfoliation of Layered Materials by Jonathan N. Coleman, Mustafa Lotya, Arlene O’Neill, Shane D. Bergin, Paul J. King, Umar Khan,  Karen Young, Alexandre Gaucher, Sukanta De, Ronan J. Smith, Igor V. Shvets, Sunil K. Arora, George Stanton, Hye-Young Kim, Kangho Lee, Gyu Tae Kim, Georg S. Duesberg, Toby Hallam, John J. Boland, Jing Jing Wang, John F. Donegan, Jaime C. Grunlan, Gregory Moriarty, Aleksey Shmeliov, Rebecca J. Nicholls, James M. Perkins, Eleanor M. Grieveson, Koenraad Theuwissen, David W. McComb, Peter D. Nellist, and Valeria Nicolosi in Science 4 February 2011: Vol. 331 no. 6017 pp. 568-571 DOI: 10.1126/science.1194975

If they could be easily exfoliated, layered materials would become a diverse source of two-dimensional crystals whose properties would be useful in applications ranging from electronics to energy storage. We show that layered compounds such as MoS2, WS2, MoSe2, MoTe2, TaSe2, NbSe2, NiTe2, BN, and Bi2Te3 can be efficiently dispersed in common solvents and can be deposited as individual flakes or formed into films. Electron microscopy strongly suggests that the material is exfoliated into individual layers. By blending this material with suspensions of other nanomaterials or polymer solutions, we can prepare hybrid dispersions or composites, which can be cast into films. We show that WS2 and MoS2 effectively reinforce polymers, whereas WS2/carbon nanotube hybrid films have high conductivity, leading to promising thermoelectric properties.

This announcement comes during Ireland’s Nanoweek 2012 (Sept. 14 – 21, 2012) which I mentioned along with other nano-themed events currently taking place in Ireland in my Sept. 14, 2012 posting.

Future of Film & Video event being livestreamed from Dublin’s Science Gallery July 13, 2012

As I’ve noted previously (my April 29, 2011 posting) Dublin is celebrating itself as a ‘City of Science’ this year. As part of the festivities (e.g. the Euroscience Open Forum [ESOF} meetings are now taking place in Dublin), the Future of Film & Video at the Science Gallery will be livestreamed on Friday, July 13, 2012 from 1800 to 1930 hours (10 am – 11:30 am PST), from the event page,

Join Academy award winners Anil Kokaram and Simon Robinson, and BAFTA award winner Mark Jacobs as they discuss the future of film and video, from today’s cutting-edge 3D tech, to tomorrow’s innovations being imagined in labs across the world. You’ll never look at a screen the same way as these visionaries show that in the film and video industry you should expect the unexpected.

This event is part of the UCD Imagine Science Film Festival, and is part of Dublin City of Science. We are grateful for the support of Google Dublin, the Chrome-Media Group at Google, Mountain View, the Sigmedia Group in the Engineering Dept, Trinity College Dublin and also Science Foundation Ireland.”

Simon Robinson

Academy Award winner, Simon Robinson is a Founder and the Chief Scientist of The Foundry, one of the most well recognised names in the creation of visual effects software. His technology has touched most of the blockbusters that reach our screens today e.g. Oscar Winning titles Hugo, Rango and effects laden works such as The Matrix, The Lord of the Rings and Avatar. In 2007 he was awarded a SciTech Academy Award for his influence on motion picture technology and in 2010 he was ranked in the top 100 most creative people in business in the fast Company’s annual ranking. His company has made the Sunday Times tech track top 100 list for two years in a row. The Foundry now numbers over 100 employees and speaking to the FT recently Simon is quoted as saying , “We never wanted to grow beyond six staff. We never thought we would sell it. We never thought we would buy it back. We are often wrong.”

Mark Jacobs

Mark Jacobs is a BAFTA award winning Producer/Director with a unique track record in innovation. His extensive experience of more than 25 years in broadcasting, with the BBC and other organisations, ranges from traditional programme making and commissioning, to delivering cutting edge innovation. Mark pioneered some of the first applications of 3D animation for both the BBC and Discovery and in 2000 he joined the BBC’s R&D arm to help pioneer new ways of using multimedia content.  Mark has recently produced a 40 minute, multi-screen interactive film for the Natural History Museum with David Attenborough and led the BBC’s series of natural history documentary trials for stereo 3D production. He has a BAFTA for Interactive TV/ Mobile and introduced some of the first tests in computer graphics and augmented reality into the BBC. He has produced many award winning films for BBC series, ranging from Wildlife On One and Supersense to landmark series on the natural history of Polynesia and Central America and also a programme on the Dingle Dolphin!

Anil Kokaram

Academy award winner, Anil Kokaram is a Professor at Trinity College Dublin with a long history in developing new technologies for digital video processing and particularly in the art of making old movies look like new. He started a company called GreenParrotPictures in 2004 which specialised in translating cinematic effects tools into the semi-professional and consumer space. In 2007 Anil was awarded a SciTech Academy award for his work in developing motion estimation technology for the cinema industry in collaboration with Simon Robinson.  GreenParrotPictures was acquired by Google in 2011 and Anil now heads a team of engineers in the Chrome Media Group in the Googleplex, Mountain View, California developing new video tools for Chrome and YouTube.  He continues to collaborate with his research group www.sigmedia.tv in Trinity College Dublin.

Location:

Paccar Theatre

Admission:

Free – prebooking essential  [go to event page to prebook]

I’m hoping this will be focussed on something other than the future of 3D technology.

Transforming flat screens with P-type conductors at CRANN

I’m not sure about window-integrated flat screens as one of the applications for this technology breakthrough at Trinity College Dublin’s (TCD) CRANN (Centre for Research on Adaptive Nanostructures and Nanodevices). I think there’s enough signage and video being beamed at me everywhere I go but all indications are that more and more surfaces are going to become display and/or communication devices and these researchers seem to have found a way to speed that process.

From the March 21, 2012 news item on Nanowerk,

Researchers at CRANN, the Science Foundation Ireland funded nanoscience institute based in Trinity College Dublin (TCD), have discovered a new material that could transform the quality, lifespan and efficiency of flat screen computers, televisions and other devices (see paper in Applied Physics Letters: “Magnesium, nitrogen codoped Cr2O3: A p-type transparent conducting oxide”).

The research team was led by Prof Igor Shvets, a CRANN Principal Investigator who has successfully launched and sold two spin out companies from TCD and who is involved in the Spirit of Ireland energy project. A patent application protecting the new material was filed by TCD. Commenting on the research, Prof Igor Shvets said, “This is an exciting development with a range of applications and we are hopeful this initial research will attract commercial interest in order to explore its industrial use. The new material could lead to innovations such as window-integrated flat screens and to increase the efficiency of certain solar cells, thus significantly impacting on the take-up of solar cells, which can help us to reduce carbon emissions.” [emphasis mine]

The application for solar cells sounds a lot more appealing to me. CRANN issued a March 21, 2012 press release which included some technical details,

Devices that the new material could be used with such as solar cells, flat screen TVs, computer monitors, LEDs all utilise materials that can conduct electricity and at the same time are see-through.  These devices currently use transparent conducting oxides, which are a good compromise between electrical conductivity and optical transparency. They all have one fundamental limitation: they all conduct electricity through the movement of electrons. [emphasis mine] Such materials are referred to as n-type transparent conducting oxides. Electricity can also be conducted through as p-type materials.  Modern day electronics make use of n-type and p-type materials.  The lack of good quality p-type transparent conducting oxides, however, led the research team to develop a new material – a p-type transparent conducting oxide.

I wish I better understood the fundamental limitation of an n-type transparent conducting oxide and how the new p-type transparent conducting oxide addresses that limitation.

After reading the description of p-type materials, it seems to me that electrons also move in that material. From the Wikipedia essay on p-type materials,

The dopant atom accepts an electron, causing the loss of half of one bond from the neighboring atom and resulting in the formation of a “hole”. Each hole is associated with a nearby negatively charged dopant ion, and the semiconductor remains electrically neutral as a whole. However, once each hole has wandered away into the lattice, one proton in the atom at the hole’s location will be “exposed” and no longer cancelled by an electron. [emphasis mine] This atom will have 3 electrons and 1 hole surrounding a particular nucleus with 4 protons. For this reason a hole behaves as a positive charge. When a sufficiently large number of acceptor atoms are added, the holes greatly outnumber thermal excited electrons. Thus, holes are the majority carriers, while electrons become minority carriers in p-type materials.

Well, I am interpreting the “wandering away” bit as a type of movement so I find the descriptions just a bit confusing. As for the holes being the majority carrier in p-type materials, perhaps the electrons in the n-type materials are the majority carriers?

If there’s anyone out there who could help lift the veil of confusion, I would much appreciate it.

For those who don’t need as much handholding as I do, you can find out more about Shvets and his work here.

International art/science script competition ceremony will be hosted by Trinity College Dublin’s nano centre and STAGE

CRANN (Centre for Research on Adaptive Nanostructures and Nanodevices) at Trinity College Dublin has announced that it will be co-hosting the winner’s ceremony (and a reading of the winning script) for an international scriptwriting contest featuring science- and technology-inspired plays. From the Jan. 11, 2012 news item on Nanowerk,

CRANN, the SFI [Science Foundation of Ireland] funded nanoscience centre based at Trinity College Dublin, today announced that it is bringing the STAGE International Script Competition to Ireland during Dublin City of Science 2012. The competition judges will include a Pulitzer Prize winner and a Nobel Laureate.

The STAGE International Script Competition is a unique collaboration between art and science that awards a prize of $10,000 for the best new play about science and technology. STAGE – Scientists, Technologists and Artists Generating Exploration – began as an alliance between the Professional Artists Lab, a dynamic artistic laboratory, and the California NanoSystems Institute (CNSI) at the University of California, Santa Barbara. Through CRANN’s relationship with CNSI, Dublin has beaten off stiff international competition to bring STAGE to Ireland.

As the 2012 City of Science, Dublin will host a programme of science-related events and activities throughout the year. The city will host Europe’s largest science conference, the Euroscience Open Forum (ESOF) 2012 from July 11-15, 2012, at which the winner of the 5th STAGE International Script Competition will first be announced to the public.

Later in the year, STAGE and CRANN will collaboratively host the award ceremony, at which the winning playwright will receive their STAGE Award from a science Nobel Laureate. In tandem with the ceremony, there will be a staged reading of the winning play, performed by professional Irish actors. Nancy Kawalek, Founder/Director of STAGE, will direct the reading.

Unfortunately, it’s too late for interested parties to submit their plays for this cycle (the 5th); submissions were closed as of Dec. 1, 2011.

The competition certainly seems to have attracted some high profile interest in past years (from the news item on Nanowerk),

Each cycle, the winner of the STAGE International Script Competition is chosen by a stellar panel of judges. Judges for the last cycle were Pulitzer Prize and Tony-Award winning playwright David Auburn; Tony, Olivier, and Obie Award-winning playwright John Guare; Nobel Laureate Alan Heeger; Nobel Laureate and KBE Sir Anthony Leggett; and Pulitzer Prize-winning playwright David Lindsay-Abaire. In addition to Mr. Lindsay-Abaire, who has shown his support for STAGE by signing on as a judge ‘in perpetuity’, the judges for this 5th cycle of the competition will include two science Nobel Laureates and two additional distinguished writer-artists from the theatre world. The names of these jurors will be announced in early 2012.

The 3rd cycle winner was a play about Rosalind Franklin; I’ve long been interested in her story and  I mentioned it in a July 28, 2010 post about science-inspired knitting (there’s a ‘Rosalind’ scarf),

For anyone not familiar with Franklin (from the San Diego Super Computer Center at the University of Southern California web page),

There is probably no other woman scientist with as much controversy surrounding her life and work as Rosalind Franklin. Franklin was responsible for much of the research and discovery work that led to the understanding of the structure of deoxyribonucleic acid, DNA. The story of DNA is a tale of competition and intrigue, told one way in James Watson’s book The Double Helix, and quite another in Anne Sayre’s study, Rosalind Franklin and DNA. James Watson, Francis Crick, and Maurice Wilkins received a Nobel Prize for the double-helix model of DNA in 1962, four years after Franklin’s death at age 37 from ovarian cancer.

Here’s a bit more about the 3rd cycle STAGE winner, Photograph 51, from the news item on Nanowerk,

A film version of third STAGE Competition winner Photograph 51 is being produced by Academy Award-nominated director Darren Aronofsky (Black Swan), Academy Award-winning actress Rachel Weisz, and Ari Handel. Playwright Anna Ziegler will adapt her play for the screen. Photograph 51 was featured at the 2011 World Science Festival in New York City; the play has also enjoyed prestigious productions in New York City and Washington, D.C.

 

About the Play: What does a woman have to do to succeed in the world of science? It is 1953 and Dr. Rosalind Franklin, brilliant, passionate and ambitious, pours herself into her work at King’s College Lab in London. When fellow scientists Watson and Crick find out about her discoveries in the field of DNA, her work is suddenly not her own – and shortly thereafter they claim credit for a major breakthrough. A compelling drama about a woman’s sacrifice for professional success, Photograph 51 asks how we become who we become, and whether we have any power to change.

I checked the playwright’s, Anna Ziegler, website for more information about the upcoming movie and found this,

Anna has been awarded [April 2011] a Tribeca Film Festival / Sloan Grant to adapt her play PHOTOGRAPH 51 into a film. Rachel Weisz, Ari Handel, Audrey Rosenberg and Darren Aronofsky are producers.

You can find out more about STAGE and other winners of the competition here.