Tag Archives: True love with AI (artificial intelligence): The Nature of Things explores emotional and creative AI (long read)

Should AI algorithms get patents for their inventions and is anyone talking about copyright for texts written by AI algorithms?

A couple of Australian academics have written a comment for the journal Nature, which bears the intriguing subtitle: “The patent system assumes that inventors are human. Inventions devised by machines require their own intellectual property law and an international treaty.” (For the curious, I’ve linked to a few of my previous posts touching on intellectual property [IP], specifically the patent’s fraternal twin, copyright at the end of this piece.)

Before linking to the comment, here’s the May 27, 2022 University of New South Wales (UNCSW) press release (also on EurekAlert but published May 30, 2022) which provides an overview of their thinking on the subject, Note: Links have been removed,

It’s not surprising these days to see new inventions that either incorporate or have benefitted from artificial intelligence (AI) in some way, but what about inventions dreamt up by AI – do we award a patent to a machine?

This is the quandary facing lawmakers around the world with a live test case in the works that its supporters say is the first true example of an AI system named as the sole inventor.

In commentary published in the journal Nature, two leading academics from UNSW Sydney examine the implications of patents being awarded to an AI entity.

Intellectual Property (IP) law specialist Associate Professor Alexandra George and AI expert, Laureate Fellow and Scientia Professor Toby Walsh argue that patent law as it stands is inadequate to deal with such cases and requires legislators to amend laws around IP and patents – laws that have been operating under the same assumptions for hundreds of years.

The case in question revolves around a machine called DABUS (Device for the Autonomous Bootstrapping of Unified Sentience) created by Dr Stephen Thaler, who is president and chief executive of US-based AI firm Imagination Engines. Dr Thaler has named DABUS as the inventor of two products – a food container with a fractal surface that helps with insulation and stacking, and a flashing light for attracting attention in emergencies.

For a short time in Australia, DABUS looked like it might be recognised as the inventor because, in late July 2021, a trial judge accepted Dr Thaler’s appeal against IP Australia’s rejection of the patent application five months earlier. But after the Commissioner of Patents appealed the decision to the Full Court of the Federal Court of Australia, the five-judge panel upheld the appeal, agreeing with the Commissioner that an AI system couldn’t be named the inventor.

A/Prof. George says the attempt to have DABUS awarded a patent for the two inventions instantly creates challenges for existing laws which has only ever considered humans or entities comprised of humans as inventors and patent-holders.

“Even if we do accept that an AI system is the true inventor, the first big problem is ownership. How do you work out who the owner is? An owner needs to be a legal person, and an AI is not recognised as a legal person,” she says.

Ownership is crucial to IP law. Without it there would be little incentive for others to invest in the new inventions to make them a reality.

“Another problem with ownership when it comes to AI-conceived inventions, is even if you could transfer ownership from the AI inventor to a person: is it the original software writer of the AI? Is it a person who has bought the AI and trained it for their own purposes? Or is it the people whose copyrighted material has been fed into the AI to give it all that information?” asks A/Prof. George.

For obvious reasons

Prof. Walsh says what makes AI systems so different to humans is their capacity to learn and store so much more information than an expert ever could. One of the requirements of inventions and patents is that the product or idea is novel, not obvious and is useful.

“There are certain assumptions built into the law that an invention should not be obvious to a knowledgeable person in the field,” Prof. Walsh says.

“Well, what might be obvious to an AI won’t be obvious to a human because AI might have ingested all the human knowledge on this topic, way more than a human could, so the nature of what is obvious changes.”

Prof. Walsh says this isn’t the first time that AI has been instrumental in coming up with new inventions. In the area of drug development, a new antibiotic was created in 2019 – Halicin – that used deep learning to find a chemical compound that was effective against drug-resistant strains of bacteria.

“Halicin was originally meant to treat diabetes, but its effectiveness as an antibiotic was only discovered by AI that was directed to examine a vast catalogue of drugs that could be repurposed as antibiotics. So there’s a mixture of human and machine coming into this discovery.”

Prof. Walsh says in the case of DABUS, it’s not entirely clear whether the system is truly responsible for the inventions.

“There’s lots of involvement of Dr Thaler in these inventions, first in setting up the problem, then guiding the search for the solution to the problem, and then interpreting the result,” Prof. Walsh says.

“But it’s certainly the case that without the system, you wouldn’t have come up with the inventions.”

Change the laws

Either way, both authors argue that governing bodies around the world will need to modernise the legal structures that determine whether or not AI systems can be awarded IP protection. They recommend the introduction of a new ‘sui generis’ form of IP law – which they’ve dubbed ‘AI-IP’ – that would be specifically tailored to the circumstances of AI-generated inventiveness. This, they argue, would be more effective than trying to retrofit and shoehorn AI-inventiveness into existing patent laws.

Looking forward, after examining the legal questions around AI and patent law, the authors are currently working on answering the technical question of how AI is going to be inventing in the future.

Dr Thaler has sought ‘special leave to appeal’ the case concerning DABUS to the High Court of Australia. It remains to be seen whether the High Court will agree to hear it. Meanwhile, the case continues to be fought in multiple other jurisdictions around the world.

Here’s a link to and a citation for the paper,

Artificial intelligence is breaking patent law by Alexandra George & Toby Walsh. Nature (Nature) COMMENT ISSN 1476-4687 (online) 24 May 2022 ISSN 0028-0836 (print) Vol 605 26 May 2022 pp. 616-18 DOI: 10.1038/d41586-022-01391-x

This paper appears to be open access.

The Journey

DABIUS has gotten a patent in one jurisdiction, from an August 8, 2021 article on brandedequity.com,

The patent application listing DABUS as the inventor was filed in patent offices around the world, including the US, Europe, Australia, and South Afica. But only South Africa granted the patent (Australia followed suit a few days later after a court judgment gave the go-ahard [and rejected it several months later]).

Natural person?

This September 27, 2021 article by Miguel Bibe for Inventa covers some of the same ground adding some some discussion of the ‘natural person’ problem,

The patent is for “a food container based on fractal geometry”, and was accepted by the CIPC [Companies and Intellectual Property Commission] on June 24, 2021. The notice of issuance was published in the July 2021 “Patent Journal”.  

South Africa does not have a substantive patent examination system and, instead, requires applicants to merely complete a filing for their inventions. This means that South Africa patent laws do not provide a definition for “inventor” and the office only proceeds with a formal examination in order to confirm if the paperwork was filled correctly.

… according to a press release issued by the University of Surrey: “While patent law in many jurisdictions is very specific in how it defines an inventor, the DABUS team is arguing that the status quo is not fit for purpose in the Fourth Industrial Revolution.”

On the other hand, this may not be considered as a victory for the DABUS team since several doubts and questions remain as to who should be considered the inventor of the patent. Current IP laws in many jurisdictions follow the traditional term of “inventor” as being a “natural person”, and there is no legal precedent in the world for inventions created by a machine.

August 2022 update

Mike Masnick in an August 15, 2022 posting on Techdirt provides the latest information on Stephen Thaler’s efforts to have patents and copyrights awarded to his AI entity, DABUS,

Stephen Thaler is a man on a mission. It’s not a very good mission, but it’s a mission. He created something called DABUS (Device for the Autonomous Bootstrapping of Unified Sentience) and claims that it’s creating things, for which he has tried to file for patents and copyrights around the globe, with his mission being to have DABUS named as the inventor or author. This is dumb for many reasons. The purpose of copyright and patents are to incentivize the creation of these things, by providing to the inventor or author a limited time monopoly, allowing them to, in theory, use that monopoly to make some money, thereby making the entire inventing/authoring process worthwhile. An AI doesn’t need such an incentive. And this is why patents and copyright only are given to persons and not animals or AI.

… Thaler’s somewhat quixotic quest continues to fail. The EU Patent Office rejected his application. The Australian patent office similarly rejected his request. In that case, a court sided with Thaler after he sued the Australian patent office, and said that his AI could be named as an inventor, but thankfully an appeals court set aside that ruling a few months ago. In the US, Thaler/DABUS keeps on losing as well. Last fall, he lost in court as he tried to overturn the USPTO ruling, and then earlier this year, the US Copyright Office also rejected his copyright attempt (something it has done a few times before). In June, he sued the Copyright Office over this, which seems like a long shot.

And now, he’s also lost his appeal of the ruling in the patent case. CAFC, the Court of Appeals for the Federal Circuit — the appeals court that handles all patent appeals — has rejected Thaler’s request just like basically every other patent and copyright office, and nearly all courts.

If you have the time, the August 15, 2022 posting is an interesting read.

Consciousness and ethical AI

Just to make things more fraught, an engineer at Google has claimed that one of their AI chatbots has consciousness. From a June 16, 2022 article (in Canada’s National Post [previewed on epaper]) by Patrick McGee,

Google has ignited a social media firestorm on the the nature of consciousness after placing an engineer on paid leave with his belief that the tech group’s chatbot has become “sentient.”

Blake Lemoine, a senior software engineer in Google’s Responsible AI unit, did not receive much attention when he wrote a Medium post saying he “may be fired soon for doing AI ethics work.”

But a Saturday [June 11, 2022] profile in the Washington Post characterized Lemoine as “the Google engineer who thinks “the company’s AI has come to life.”

This is not the first time that Google has run into a problem with ethics and AI. Famously, Timnit Gebru who co-led (with Margaret Mitchell) Google’s ethics and AI unit departed in 2020. Gebru said (and maintains to this day) she was fired. They said she was ?, they never did make a final statement although after an investigation Gebru did receive an apology. You *can* read more about Gebru and the issues she brought to light in her Wikipedia entry. Coincidentally (or not), Margaret Mitchell was terminated/fired in February 2021 from Google after criticizing the company for Gebru’s ‘firing’. See a February 19, 2021 article by Megan Rose Dickey for TechCrunch for details about what the company has admitted is a firing or Margaret Mitchell’s termination from the company.

Getting back intellectual property and AI.

What about copyright?

There are no mentions of copyright in the earliest material I have here about the ‘creative’ arts and artificial intelligence is this, “Writing and AI or is a robot writing this blog?” posted July 16, 2014. More recently, there’s “Beer and wine reviews, the American Chemical Society’s (ACS) AI editors, and the Turing Test” posted May 20, 2022. The type of writing featured is not literary or typically considered creative writing.

On the more creative front, there’s “True love with AI (artificial intelligence): The Nature of Things explores emotional and creative AI (long read)” posted on December 3, 2021. The literary/creative portion of the post can be found under the ‘AI and creativity’ subhead approximately 30% of the way down and where I mention Douglas Coupland. Again, there’s no mention of copyright.

It’s with the visual arts that copyright gets mentioned. The first one I can find here is “Robot artists—should they get copyright protection” posted on July 10, 2017.

Fun fact: Andres Guadamuz who was mentioned in my posting took to his own blog where he gave my blog a shout out while implying that I wasn’t thoughtful. The gist of his August 8, 2017 posting was that he was misunderstood by many people, which led to the title for his post, “Should academics try to engage the public?” Thankfully, he soldiers on trying to educate us with his TechnoLama blog.

Lastly, there’s this August 16, 2019 posting “AI (artificial intelligence) artist got a show at a New York City art gallery” where you can scroll down to the ‘What about intellectual property?’ subhead about 80% of the way.

You look like a thing …

i am recommending a book for anyone who’d like to learn a little more about how artificial intelligence (AI) works, “You look like a thing and I love you; How Artificial Intelligence Works and Why It’s Making the World a Weirder Place” by Janelle Shane (2019).

It does not require an understanding of programming/coding/algorithms/etc.; Shane makes the subject as accessible as possible and gives you insight into why the term ‘artificial stupidity’ is more applicable than you might think. You can find Shane’s website here and you can find her 10 minute TED talk here.

*’can’ added to sentence on May 12, 2023.

An emotional android child

Caption: The six emotional expressions assessed in the second experiment. See if you can identify them! Note: this is a video made by filming Nikola’s head as it sat on a desk – it is not a computer animated graphic. Credit: RIKEN

This work comes from Japan according to a February 16, 2022 news item on ScienceDaily,

Researchers from the RIKEN Guardian Robot Project in Japan have made an android child named Nikola that successfully conveys six basic emotions. The new study, published in Frontiers in Psychology, tested how well people could identify six facial expressions — happiness, sadness, fear, anger, surprise, and disgust — which were generated by moving “muscles” in Nikola’s face. This is the first time that the quality of android-expressed emotion has been tested and verified for these six emotions.

A February 11, 2022 RIKEN press release (also on EurekAlert but published February 15, 2022), which originated the news item, provides more detail about the work,

Rosie the robot maid was considered science fiction when she debuted on the Jetson’s cartoon over 50 years ago. Although the reality of the helpful robot is currently more science and less fiction, there are still many challenges that need to be met, including being able to detect and express emotions. The recent study led by Wataru Sato from the RIKEN Guardian Robot Project focused on building a humanoid robot, or android, that can use its face to express a variety of emotions. The result is Nikola, an android head that looks like a hairless boy.

Inside Nikola’s face are 29 pneumatic actuators that control the movements of artificial muscles. Another 6 actuators control head and eyeball movements. Pneumatic actuators are controlled by air pressure, which makes the movements silent and smooth. The team placed the actuators based on the Facial Action Coding System (FACS), which has been used extensively to study facial expressions. Past research has identified numerous facial action units—such as ‘cheek raiser’ and ‘lip pucker’—that comprise typical emotions such as happiness or disgust, and the researchers incorporated these action units in Nikola’s design.

Typically, studies of emotions, particularly how people react to emotions, have a problem. It is difficult to do a properly controlled experiment with live people interacting, but at the same time, looking at photos or videos of people is less natural, and reactions aren’t the same. “The hope is that with androids like Nikola, we can have our cake and eat it too,” says Sato. “We can control every aspect of Nikola’s behavior, and at the same time study live interactions.” The first step was to see if Nikola’s facial expressions were understandable.

A person certified in FACS [Facial Action Coding System] scoring was able to identify each facial action unit, indicating that Nikola’s facial movements accurately resemble those of a real human. A second test showed that everyday people could recognize the six prototypical emotions—happiness, sadness, fear, anger, surprise, and disgust—in Nikola’s face, albeit to varying accuracies. This is because Nikola’s silicone skin is less elastic than real human skin and cannot form wrinkles very well. Thus, emotions like disgust were harder to identify because the action unit for nose wrinkling could not be included.

“In the short term, androids like Nikola can be important research tools for social psychology or even social neuroscience,” says Sato. “Compared with human confederates, androids are good at controlling behaviors and can facilitate rigorous empirical investigation of human social interactions.” As an example, the researchers asked people to rate the naturalness of Nikola’s emotions as the speed of his facial movements was systematically controlled. They researchers found that the most natural speed was slower for some emotions like sadness than it was for others like surprise.

While Nikola still lacks a body, the ultimate goal of the Guardian Robot Project is to build an android that can assist people, particularly those which physical needs who might live alone. “Androids that can emotionally communicate with us will be useful in a wide range of real-life situations, such as caring for older people, and can promote human wellbeing,” says Sato.

Here’s a link to and a citation for the paper,

An Android for Emotional Interaction: Spatiotemporal Validation of Its Facial Expressions by Wataru Sato, Shushi Namba, Dongsheng Yang, Shin’ya Nishida, Carlos Ishi, and Takashi Minato. Front. Psychol., 04 February 2022 DOI: https://doi.org/10.3389/fpsyg.2021.800657

This paper is open access.

For anyone who’d like to investigate the worlds of robots, artificial intelligence, and emotions, I have my December 3, 2021 posting “True love with AI (artificial intelligence): The Nature of Things explores emotional and creative AI (long read)” and there’s also Hiroshi Ishiguro’s work, which I’ve mentioned a number of times here, most recently in a March 27, 2017 posting “Ishiguro’s robots and Swiss scientist question artificial intelligence at SXSW (South by Southwest) 2017.”

East/West collaboration on scholarship and imagination about humanity’s long-term future— six new fellows at Berggruen Research Center at Peking University

According to a January 4, 2022 Berggruen Institute (also received via email), they have appointed a new crop of fellows for their research center at Peking University,

The Berggruen Institute has announced six scientists and philosophers to serve as Fellows at the Berggruen Research Center at Peking University in Beijing, China. These eminent scholars will work together across disciplines to explore how the great transformations of our time may shift human experience and self-understanding in the decades and centuries to come.

The new Fellows are Chenjian Li, University Chair Professor at Peking University; Xianglong Zhang, professor of philosophy at Peking University; Xiaoli Liu, professor of philosophy at Renmin University of China; Jianqiao Ge, lecturer at the Academy for Advanced Interdisciplinary Studies (AAIS) at Peking University; Xiaoping Chen, Director of the Robotics Laboratory at the University of Science and Technology of China; and Haidan Chen, associate professor of medical ethics and law at the School of Health Humanities at Peking University.

“Amid the pandemic, climate change, and the rest of the severe challenges of today, our Fellows are surmounting linguistic and cultural barriers to imagine positive futures for all people,” said Bing Song, Director of the China Center and Vice President of the Berggruen Institute. “Dialogue and shared understanding are crucial if we are to understand what today’s breakthroughs in science and technology really mean for the human community and the planet we all share.”

The Fellows will investigate deep questions raised by new understandings and capabilities in science and technology, exploring their implications for philosophy and other areas of study.  Chenjian Li is considering the philosophical and ethical considerations of gene editing technology. Meanwhile, Haidan Chen is exploring the social implications of brain/computer interface technologies in China, while Xiaoli Liu is studying philosophical issues arising from the intersections among psychology, neuroscience, artificial intelligence, and art.

Jianqiao Ge’s project considers the impact of artificial intelligence on the human brain, given the relative recency of its evolution into current form. Xianglong Zhang’s work explores the interplay between literary culture and the development of technology. Finally, Xiaoping Chen is developing a new concept for describing innovation that draws from Daoist, Confucianist, and ancient Greek philosophical traditions.

Fellows at the China Center meet monthly with the Institute’s Los Angeles-based Fellows. These fora provide an opportunity for all Fellows to share and discuss their work. Through this cross-cultural dialogue, the Institute is helping to ensure continued high-level of ideas among China, the United States, and the rest of the world about some of the deepest and most fundamental questions humanity faces today.

“Changes in our capability and understanding of the physical world affect all of humanity, and questions about their implications must be pondered at a cross-cultural level,” said Bing. “Through multidisciplinary dialogue that crosses the gulf between East and West, our Fellows are pioneering new thought about what it means to be human.”

Haidan Chen is associate professor of medical ethics and law at the School of Health Humanities at Peking University. She was a visiting postgraduate researcher at the Institute for the Study of Science Technology and Innovation (ISSTI), the University of Edinburgh; a visiting scholar at the Brocher Foundation, Switzerland; and a Fulbright visiting scholar at the Center for Biomedical Ethics, Stanford University. Her research interests embrace the ethical, legal, and social implications (ELSI) of genetics and genomics, and the governance of emerging technologies, in particular stem cells, biobanks, precision medicine, and brain science. Her publications appear at Social Science & MedicineBioethics and other journals.

Xiaoping Chen is the director of the Robotics Laboratory at University of Science and Technology of China. He also currently serves as the director of the Robot Technical Standard Innovation Base, an executive member of the Global AI Council, Chair of the Chinese RoboCup Committee, and a member of the International RoboCup Federation’s Board of Trustees. He has received the USTC’s Distinguished Research Presidential Award and won Best Paper at IEEE ROBIO 2016. His projects have won the IJCAI’s Best Autonomous Robot and Best General-Purpose Robot awards as well as twelve world champions at RoboCup. He proposed an intelligent technology pathway for robots based on Open Knowledge and the Rong-Cha principle, which have been implemented and tested in the long-term research on KeJia and JiaJia intelligent robot systems.

Jianqiao Ge is a lecturer at the Academy for Advanced Interdisciplinary Studies (AAIS) at Peking University. Before, she was a postdoctoral fellow at the University of Chicago and the Principal Investigator / Co-Investigator of more than 10 research grants supported by the Ministry of Science and Technology of China, the National Natural Science Foundation of China, and Beijing Municipal Science & Technology Commission. She has published more than 20 peer-reviewed articles on leading academic journals such as PNAS, the Journal of Neuroscience, and has been awarded two national patents. In 2008, by scanning the human brain with functional MRI, Ge and her collaborator were among the first to confirm that the human brain engages distinct neurocognitive strategies to comprehend human intelligence and artificial intelligence. Ge received her Ph.D. in psychology, B.S in physics, a double B.S in mathematics and applied mathematics, and a double B.S in economics from Peking University.

Chenjian Li is the University Chair Professor of Peking University. He also serves on the China Advisory Board of Eli Lilly and Company, the China Advisory Board of Cornell University, and the Rhodes Scholar Selection Committee. He is an alumnus of Peking University’s Biology Department, Peking Union Medical College, and Purdue University. He was the former Vice Provost of Peking University, Executive Dean of Yuanpei College, and Associate Dean of the School of Life Sciences at Peking University. Prior to his return to China, he was an associate professor at Weill Medical College of Cornell University and the Aidekman Endowed Chair of Neurology at Mount Sinai School of Medicine. Dr. Li’s academic research focuses on the molecular and cellular mechanisms of neurological diseases, cancer drug development, and gene-editing and its philosophical and ethical considerations. Li also writes as a public intellectual on science and humanity, and his Chinese translation of Richard Feynman’s book What Do You Care What Other People Think? received the 2001 National Publisher’s Book Award.

Xiaoli Liu is professor of philosophy at Renmin University. She is also Director of the Chinese Society of Philosophy of Science Leader. Her primary research interests are philosophy of mathematics, philosophy of science and philosophy of cognitive science. Her main works are “Life of Reason: A Study of Gödel’s Thought,” “Challenges of Cognitive Science to Contemporary Philosophy,” “Philosophical Issues in the Frontiers of Cognitive Science.” She edited “Symphony of Mind and Machine” and series of books “Mind and Cognition.” In 2003, she co-founded the “Mind and Machine workshop” with interdisciplinary scholars, which has held 18 consecutive annual meetings. Liu received her Ph.D. from Peking University and was a senior visiting scholar in Harvard University.

Xianglong Zhang is a professor of philosophy at Peking University. His research areas include Confucian philosophy, phenomenology, Western and Eastern comparative philosophy. His major works (in Chinese except where noted) include: Heidegger’s Thought and Chinese Tao of HeavenBiography of HeideggerFrom Phenomenology to ConfuciusThe Exposition and Comments of Contemporary Western Philosophy; The Exposition and Comments of Classic Western PhilosophyThinking to Take Refuge: The Chinese Ancient Philosophies in the GlobalizationLectures on the History of Confucian Philosophy (four volumes); German Philosophy, German Culture and Chinese Philosophical ThinkingHome and Filial Piety: From the View between the Chinese and the Western.

About the Berggruen China Center
Breakthroughs in artificial intelligence and life science have led to the fourth scientific and technological revolution. The Berggruen China Center is a hub for East-West research and dialogue dedicated to the cross-cultural and interdisciplinary study of the transformations affecting humanity. Intellectual themes for research programs are focused on frontier sciences, technologies, and philosophy, as well as issues involving digital governance and globalization.

About the Berggruen Institute:
The Berggruen Institute’s mission is to develop foundational ideas and shape political, economic, and social institutions for the 21st century. Providing critical analysis using an outwardly expansive and purposeful network, we bring together some of the best minds and most authoritative voices from across cultural and political boundaries to explore fundamental questions of our time. Our objective is enduring impact on the progress and direction of societies around the world. To date, projects inaugurated at the Berggruen Institute have helped develop a youth jobs plan for Europe, fostered a more open and constructive dialogue between Chinese leadership and the West, strengthened the ballot initiative process in California, and launched Noema, a new publication that brings thought leaders from around the world together to share ideas. In addition, the Berggruen Prize, a $1 million award, is conferred annually by an independent jury to a thinker whose ideas are shaping human self-understanding to advance humankind.

You can find out more about the Berggruen China Center here and you can access a list along with biographies of all the Berggruen Institute fellows here.

Getting ready

I look forward to hearing about the projects from these thinkers.

Gene editing and ethics

I may have to reread some books in anticipation of Chenjian Li’s philosophical work and ethical considerations of gene editing technology. I wonder if there’ll be any reference to the He Jiankui affair.

(Briefly for those who may not be familiar with the situation, He claimed to be the first to gene edit babies. In November 2018, news about the twins, Lulu and Nana, was a sensation and He was roundly criticized for his work. I have not seen any information about how many babies were gene edited for He’s research; there could be as many as six. My July 28, 2020 posting provided an update. I haven’t stumbled across anything substantive since then.)

There are two books I recommend should you be interested in gene editing, as told through the lens of the He Jiankui affair. If you can, read both as that will give you a more complete picture.

In no particular order: This book provides an extensive and accessible look at the science, the politics of scientific research, and some of the pressures on scientists of all countries. Kevin Davies’ 2020 book, “Editing Humanity; the CRISPR Revolution and the New Era of Genome Editing” provides an excellent introduction from an insider. Here’s more from Davies’ biographical sketch,

Kevin Davies is the executive editor of The CRISPR Journal and the founding editor of Nature Genetics . He holds an MA in biochemistry from the University of Oxford and a PhD in molecular genetics from the University of London. He is the author of Cracking the Genome, The $1,000 Genome, and co-authored a new edition of DNA: The Story of the Genetic Revolution with Nobel Laureate James D. Watson and Andrew Berry. …

The other book is “The Mutant Project; Inside the Global Race to Genetically Modify Humans” (2020) by Eben Kirksey, an anthropologist who has an undergraduate degree in one of the sciences. He too provides scientific underpinning but his focus is on the cultural and personal underpinnings of the He Jiankui affair, on the culture of science research, irrespective of where it’s practiced, and the culture associated with the DIY (do-it-yourself) Biology community. Here’s more from Kirksey’s biographical sketch,

EBEN KIRKSEY is an American anthropologist and Member of the Institute for Advanced Study in Princeton, New Jersey. He has been published in Wired, The Atlantic, The Guardian and The Sunday Times . He is sought out as an expert on science in society by the Associated Press, The Wall Street Journal, The New York Times, Democracy Now, Time and the BBC, among other media outlets. He speaks widely at the world’s leading academic institutions including Oxford, Yale, Columbia, UCLA, and the International Summit of Human Genome Editing, plus music festivals, art exhibits, and community events. Professor Kirksey holds a long-term position at Deakin University in Melbourne, Australia.

Brain/computer interfaces (BCI)

I’m happy to see that Haidan Chen will be exploring the social implications of brain/computer interface technologies in China. I haven’t seen much being done here in Canada but my December 23, 2021 posting, Your cyborg future (brain-computer interface) is closer than you think, highlights work being done at the Imperial College London (ICL),

“For some of these patients, these devices become such an integrated part of themselves that they refuse to have them removed at the end of the clinical trial,” said Rylie Green, one of the authors. “It has become increasingly evident that neurotechnologies have the potential to profoundly shape our own human experience and sense of self.”

You might also find my September 17, 2020 posting has some useful information. Check under the “Brain-computer interfaces, symbiosis, and ethical issues” subhead for another story about attachment to one’s brain implant and also the “Finally” subhead for more reading suggestions.

Artificial intelligence (AI), art, and the brain

I’ve lumped together three of the thinkers, Xiaoli Liu, Jianqiao Ge and Xianglong Zhang, as there is some overlap (in my mind, if nowhere else),

  • Liu’s work on philosophical issues as seen in the intersections of psychology, neuroscience, artificial intelligence, and art
  • Ge’s work on the evolution of the brain and the impact that artificial intelligence may have on it
  • Zhang’s work on the relationship between literary culture and the development of technology

A December 3, 2021 posting, True love with AI (artificial intelligence): The Nature of Things explores emotional and creative AI (long read), is both a review of a recent episode of the Canadian Broadcasting Corporation’s (CBC) science television series,The Nature of Things, and a dive into a number of issues as can be seen under subheads such as “AI and Creativity,” “Kazuo Ishiguro?” and “Evolution.”

You may also want to check out my December 27, 2021 posting, Ai-Da (robot artist) writes and performs poem honouring Dante’s 700th anniversary, for an eye opening experience. If nothing else, just watch the embedded video.

This suggestion relates most closely to Ge’s and Zhang’s work. If you haven’t already come across it, there’s Walter J. Ong’s 1982 book, “Orality and Literacy: The Technologizing of the Word.” From the introductory page of the 2002 edition (PDF),

This classic work explores the vast differences between oral and
literate cultures and offers a brilliantly lucid account of the
intellectual, literary and social effects of writing, print and
electronic technology. In the course of his study, Walter J.Ong
offers fascinating insights into oral genres across the globe and
through time and examines the rise of abstract philosophical and
scientific thinking. He considers the impact of orality-literacy
studies not only on literary criticism and theory but on our very
understanding of what it is to be a human being, conscious of self
and other.

In 2013, a 30th anniversary edition of the book was released and is still in print.

Philosophical traditions

I’m very excited to learn more about Xiaoping Chen’s work describing innovation that draws from Daoist, Confucianist, and ancient Greek philosophical traditions.

Should any of my readers have suggestions for introductory readings on these philosophical traditions, please do use the Comments option for this blog. In fact, if you have suggestions for other readings on these topics, I would be very happy to learn of them.

Congratulations to the six Fellows at the Berggruen Research Center at Peking University in Beijing, China. I look forward to reading articles about your work in the Berggruen Institute’s Noema magazine and, possibly, attending your online events.

FrogHeart casts an eye back to 2021 then looks forward to 2022 and contronyms

Casting an eye back isn’t one of my strong points. Thankfully I can’t be forced into making a top 10 list of some kind. Should someone be deeply disappointed (tongue in cheek) that I failed to mention one of the big 2021 stories featured here, please leave a note in the Comments for this blog and I’ll do my best to add it.

Note: I very rarely feature space exploration unless there’s a nanotechnology or other emerging technology angle to it. There are a lot of people who do a much better job of covering space exploration than I can. (If you’re interested in an overview from a Canadian on the international race to space, you can start with this December 29, 2021 posting “Looking back at a booming year in space” by Bob McDonald of CBC’s [Canadian Broadcasting Corporation] Quirks & Quarks science radio programme.)

Now, onto FrogHeart’s latest year.

2021

One of the standout stories in 2020/21 here and many, many places was the rise of the biotechnology community in British Columbia and elsewhere in Canada. Lipid nanoparticles used in COVID-19 vaccines became far better known than they ever had before and AbCellera took the business world by storm as its founder became a COVID billionaire.

Here is a sampling of the BC biotechnology/COVID-19 stories featured here,

  • “Avo Media, Science Telephone, and a Canadian COVID-19 billionaire scientist” December 30, 2020 posting
  • “Why is Precision Nanosystems Inc. in the local (Vancouver, Canada) newspaper?” January 22, 2021 posting Note: The company is best known for its work on lipid nanoparticles
  • “mRNA, COVID-19 vaccines, treating genetic diseases before birth, and the scientist who started it all” March 5, 2021 posting Note: This posting also notes a Canadian connection in relation mRNA in the subsection titled “Entrepreneurs rush in”
  • “Getting erased from the mRNA/COVID-19 story” August 20, 2021 posting Note: This features a fascinating story from Nathan Vardi (for Forbes) of professional jealousies, competitiveness, and a failure to recognize opportunity when she comes visiting.
  • “Who’s running the life science companies’ public relations campaign in British Columbia (Vancouver, Canada)?” August 23, 2021 posting Note: This explores the biotech companies, the network, and provincial and federal funding, as well as, municipal (City of Vancouver) support and more.

Sadly, I did not have time to feature this September 14, 2021 article (The tangled history of mRNA vaccines; Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough.) by Elie Dolgin for Nature magazine.

Dolgin starts the story in 1987 and covers many players that were new to me although I did recognize some of the more recent and Canadian players such as Pieter Cullis and Ian MacLachlan. *ETA January 3 ,2021: Cullis and MacLachlan are both mentioned in my ‘Getting erased ..” August 20, 2021 posting.* Fun fact: Pieter Cullis was just named an Officer to the Order of Canada (from the Governor General’s December 29, 2021 news release),

Pieter Cullis, O.C.
Vancouver, British Columbia

For his contributions to the advancement of biomedical research and drug development, and for his mentorship of the next generation of scientists and entrepreneurs.

Back to this roundup, I got interested in greener lithium mining, given its importance for batteries in electric vehicles and elsewhere,

2021 seems to have been the year when the science community started podcasting in a big way. Either the podcast was started this year or I stumbled across it this year (meaning it’s likely a podcast that is getting publicized because they had a good first year and they want more listeners for their second year),

  • “New podcast—Mission: Interplanetary and Event Rap: a one-stop custom rap shop Kickstarter” April 30, 2021 posting
  • “Superstar engineers and fantastic fiction writers podcast series” June 28, 2021 posting
  • “Periodically Political: a Canadian podcast from Elect STEM” August 16, 2021 posting
  • “Unlocking Science: a new podcast series launches on November 16, 2021” November 16, 2021 posting
  • “Lost Women of Science” December 2, 2021 posting
  • “Nerdin’ About and Science Diction: a couple of science podcasts” Note: Not posted but maybe one day. Meanwhile, here they are:
    • Nerdin’ About describes itself as, “… a podcast where passionate nerds tell us about their research, their interests, and what they’ve been Nerdin’ About lately. A spin-off of Nerd Nite Vancouver, a community lecture series held in a bar, Nerdin’ About is here to explore these questions with you. Hosted by rat researcher Kaylee Byers (she/her) and astronomy educator Michael Unger (he/him). Elise Lane (she/her) is our Mixing Engineer. Music by Jay Arner. Artwork by Armin Mortazavi.”
    • Science Diction is a podcast offshoot of Science Friday (SciFri), a US National Public Radio (NPR) programme. “… Hosted by SciFri producer and self-proclaimed word nerd Johanna Mayer, each episode of Science Diction digs into the origin of a single word or phrase, and, with the help of historians, authors, etymologists, and scientists, reveals a surprising science connection. Did you know the origin of the word meme has more to do with evolutionary biology than lolcats? Or that the element cobalt takes its name from a very cheeky goblin from German folklore? …”
  • Podcast episode from the Imperial College London features women’s hearts, psychedelic worldviews, and nanotechnology for children” Note: Not posted but maybe one day.
  • Alberta-based podcast explores AI (Artificial Intelligence)” Note 1: You’ll find season one and two on the page I’ve linked to; just keep scrolling. Note 2: Not posted but maybe one day.
  • Own the Science Podcast/À vous la science balado” Note: Not posted but maybe one day.

Integrating the body with machines is an ongoing interest of mine, these particular 2021 postings stood out but there are other postings (click on the Human Enhancement category or search the tag ‘machine/flesh’),

I wrote a few major (long) pieces this year,

  • “Interior Infinite: carnival & chaos, a June 26 – September 5, 2021 show at Polygon Art Gallery (North Vancouver, Canada)” July 26, 2021 posting Note: While this isn’t an art/sci posting it does touch on a topic near and dear to my heart, writers. In particular, the literary theorist, Mikhail Mikhailovich Bakhtin.
  • “The metaverse or not” October 22, 2021 posting Note: What can I say? The marketing hype got to me.
  • “True love with AI (artificial intelligence): The Nature of Things explores emotional and creative AI (long read)” December 3, 2021 posting

2022 and contronyms

I don’t make psychic predictions. As far as I’m concerned, 2022 will be a continuation of 2021, albeit with a few surprises.

My focus on nanotechnology and emerging technologies will remain. I expect artificial intelligence, CRISPR and gene editing (in general), quantum computing (technical work and commercialization), and neuromorphic computing will continue to make news. As for anything else, well, it wouldn’t be a surprise if you knew it was coming.

With regard to this blog, I keep thinking about cutting back so I can focus on other projects. Whether I finally follow through this year is a mystery to me.

Because words and writing are important to me, I’d like to end the year with this, which I found in early December 2021. From “25 Words That Are Their Own Opposites” on getpocket.com by Judith Herman originally written for “Mental Floss and … published June 15, 2018,”

Here’s an ambiguous sentence for you: “Because of the agency’s oversight, the corporation’s behavior was sanctioned.” Does that mean, “Because the agency oversaw the company’s behavior, they imposed a penalty for some transgression,” or does it mean, “Because the agency was inattentive, they overlooked the misbehavior and gave it their approval by default”? We’ve stumbled into the looking-glass world of contronyms—words that are their own antonyms.

1. Sanction (via French, from Latin sanctio(n-), from sancire ‘ratify,’) can mean “give official permission or approval for (an action)” or conversely, “impose a penalty on.”

2. Oversight is the noun form of two verbs with contrary meanings, “oversee” and “overlook.” Oversee, from Old English ofersēon (“look at from above”) means “supervise” (medieval Latin for the same thing: super-, “over” plus videre, “to see.”) Overlook usually means the opposite: “to fail to see or observe; to pass over without noticing; to disregard, ignore.”

3. Left can mean either remaining or departed. If the gentlemen have withdrawn to the drawing room for after-dinner cigars, who’s left? (The gentlemen have left and the ladies are left.)

4. Dust, along with the next two words, is a noun turned into a verb meaning either to add or to remove the thing in question. Only the context will tell you which it is. When you dust are you applying dust or removing it? It depends whether you’re dusting the crops or the furniture.

The contronym (also spelled “contranym”) goes by many names, including auto-antonym, antagonym, enantiodrome, self-antonym, antilogy and Janus word (from the Roman god of beginnings and endings, often depicted with two faces looking in opposite directions). …

Herman made liberal use, which she acknowledged, of the Mark Nichol article/list, “75 Contronyms (Words with Contradictory Meanings)” on Daily Writing Tips (Note: Based on the ‘comments’, Nichol’s list appears to be have been posted sometime in 2011),

3. Bill: A payment, or an invoice for payment

4. Bolt: To secure, or to flee

46. Quantum: Significantly large, or a minuscule part

47. Quiddity: Essence, or a trifling point of contention

68. Trim: To decorate, or to remove excess from

69. Trip: A journey, or a stumble

Happy 2022!