It’s been quite a while since I’ve stumbled across a study about public perceptions of nanotechnology. This study is focused on public perceptions as seen on Twitter (before the Elon Musk acquisition completed on October 27, 2022). From a May 9, 2022 article by Kristy McRoberts for Chemistry World,
Scientists should be aware of the impact social media could have on their work. A new study shows that to reduce the chance of disruption due to legislative, regulatory or funding changes linked to public opinion, it is important to include social media when considering risk.
Finbarr Murphy, from the University of Limerick in Ireland, and colleagues performed a sentiment analysis of tweets between 2006 and 2020 relating to three areas of nanoscience – silver, carbon and titanium – to examine the public perception of nanotechnology. They found that overall public perception is slightly positive. But whilst positive events have little to no impact on tweet volume or perception, adverse events caused an increase in the volume of tweets presenting a negative opinion.
If an event is perceived badly enough to generate a twitterstorm, this decrease in public confidence could have far reaching impacts, with legislation, research funding and insurance coverage all susceptible to public opinion. As many research grants are through public funds, a large negative shift in public opinion towards nanotechnology could result in a decrease in funding available for research in that area.
Murphy says that ‘insurers are potentially the weak link [emphasis mine] of the scientific community’ and if insurers are impacted by a change in public opinion ‘they might begin to either exclude nanotechnology from their premiums or withdraw’.
Finbarr Murphy was last mentioned here in a December 17, 2014 posting titled: “Insurance companies, the future, and perceptions about nanotechnology risks.”
Here’s a link to and a citation for Murphy’s latest research,
A September 1, 2021 news item on ScienceDaily announces a new type of memristor from Texas A&M University (Texas A&M or TAMU) and the National University of Singapore (NUS)
In a discovery published in the journal Nature, an international team of researchers has described a novel molecular device with exceptional computing prowess.
Reminiscent of the plasticity of connections in the human brain, the device can be reconfigured on the fly for different computational tasks by simply changing applied voltages. Furthermore, like nerve cells can store memories, the same device can also retain information for future retrieval and processing.
“The brain has the remarkable ability to change its wiring around by making and breaking connections between nerve cells. Achieving something comparable in a physical system has been extremely challenging,” said Dr. R. Stanley Williams [emphasis mine], professor in the Department of Electrical and Computer Engineering at Texas A&M University. “We have now created a molecular device with dramatic reconfigurability, which is achieved not by changing physical connections like in the brain, but by reprogramming its logic.”
Dr. T. Venkatesan, director of the Center for Quantum Research and Technology (CQRT) at the University of Oklahoma, Scientific Affiliate at National Institute of Standards and Technology, Gaithersburg, and adjunct professor of electrical and computer engineering at the National University of Singapore, added that their molecular device might in the future help design next-generation processing chips with enhanced computational power and speed, but consuming significantly reduced energy.
Whether it is the familiar laptop or a sophisticated supercomputer, digital technologies face a common nemesis, the von Neumann bottleneck. This delay in computational processing is a consequence of current computer architectures, wherein the memory, containing data and programs, is physically separated from the processor. As a result, computers spend a significant amount of time shuttling information between the two systems, causing the bottleneck. Also, despite extremely fast processor speeds, these units can be idling for extended amounts of time during periods of information exchange.
As an alternative to conventional electronic parts used for designing memory units and processors, devices called memristors offer a way to circumvent the von Neumann bottleneck. Memristors, such as those made of niobium dioxide and vanadium dioxide, transition from being an insulator to a conductor at a set temperature. This property gives these types of memristors the ability to perform computations and store data.
However, despite their many advantages, these metal oxide memristors are made of rare-earth elements and can operate only in restrictive temperature regimes. Hence, there has been an ongoing search for promising organic molecules that can perform a comparable memristive function, said Williams.
Dr. Sreebrata Goswami, a professor at the Indian Association for the Cultivation of Science, designed the material used in this work. The compound has a central metal atom (iron) bound to three phenyl azo pyridine organic molecules called ligands.
“This behaves like an electron sponge that can absorb as many as six electrons reversibly, resulting in seven different redox states,” said Sreebrata. “The interconnectivity between these states is the key behind the reconfigurability shown in this work.”
Dr. Sreetosh Goswami, a researcher at the National University of Singapore, devised this project by creating a tiny electrical circuit consisting of a 40-nanometer layer of molecular film sandwiched between a layer of gold on top and gold-infused nanodisc and indium tin oxide at the bottom.
On applying a negative voltage on the device, Sreetosh witnessed a current-voltage profile that was nothing like anyone had seen before. Unlike metal-oxide memristors that can switch from metal to insulator at only one fixed voltage, the organic molecular devices could switch back and forth from insulator to conductor at several discrete sequential voltages.
“So, if you think of the device as an on-off switch, as we were sweeping the voltage more negative, the device first switched from on to off, then off to on, then on to off and then back to on. I’ll say that we were just blown out of our seat,” said Venkatesan. “We had to convince ourselves that what we were seeing was real.”
Sreetosh and Sreebrata investigated the molecular mechanisms underlying the curious switching behavior using an imaging technique called Raman spectroscopy. In particular, they looked for spectral signatures in the vibrational motion of the organic molecule that could explain the multiple transitions. Their investigation revealed that sweeping the voltage negative triggered the ligands on the molecule to undergo a series of reduction, or electron-gaining, events that caused the molecule to transition between off state and on states.
Next, to describe the extremely complex current-voltage profile of the molecular device mathematically, Williams deviated from the conventional approach of basic physics-based equations. Instead, he described the behavior of the molecules using a decision tree algorithm with “if-then-else” statements, a commonplace line of code in several computer programs, particularly digital games.
“Video games have a structure where you have a character that does something, and then something occurs as a result. And so, if you write that out in a computer algorithm, they are if-then-else statements,” said Williams. “Here, the molecule is switching from on to off as a consequence of applied voltage, and that’s when I had the eureka moment to use decision trees to describe these devices, and it worked very well.”
But the researchers went a step further to exploit these molecular devices to run programs for different real-world computational tasks. Sreetosh showed experimentally that their devices could perform fairly complex computations in a single time step and then be reprogrammed to perform another task in the next instant.
“It was quite extraordinary; our device was doing something like what the brain does, but in a very different way,” said Sreetosh. “When you’re learning something new or when you’re deciding, the brain can actually reconfigure and change physical wiring around. Similarly, we can logically reprogram or reconfigure our devices by giving them a different voltage pulse then they’ve seen before.”
Venkatesan noted that it would take thousands of transistors to perform the same computational functions as one of their molecular devices with its different decision trees. Hence, he said their technology might first be used in handheld devices, like cell phones and sensors, and other applications where power is limited.
Other contributors to the research include Dr. Abhijeet Patra and Dr. Ariando from the National University of Singapore; Dr. Rajib Pramanick and Dr. Santi Prasad Rath from the Indian Association for the Cultivation of Science; Dr. Martin Foltin from Hewlett Packard Enterprise, Colorado; and Dr. Damien Thompson from the University of Limerick, Ireland.
Venkatesan said that this research is indicative of the future discoveries from this collaborative team, which will include the center of nanoscience and engineering at the Indian Institute of Science and the Microsystems and Nanotechnology Division at the NIST.
I’ve highlighted R. Stanley Williams because he and his team at HP [Hewlett Packard] Labs helped to kick off current memristor research in 2008 with the publication of two papers as per my April 5, 2010 posting,
In 2008, two memristor papers were published in Nature and Nature Nanotechnology, respectively. In the first (Nature, May 2008 [article still behind a paywall], a team at HP Labs claimed they had proved the existence of memristors (a fourth member of electrical engineering’s ‘Holy Trinity of the capacitor, resistor, and inductor’). In the second paper (Nature Nanotechnology, July 2008 [article still behind a paywall]) the team reported that they had achieved engineering control.
Many electronic devices today are dependent on semiconductor logic circuits based on switches hard-wired to perform predefined logic functions. Physicists from the National University of Singapore (NUS), together with an international team of researchers, have developed a novel molecular memristor, or an electronic memory device, that has exceptional memory reconfigurability.
Unlike hard-wired standard circuits, the molecular device can be reconfigured using voltage to embed different computational tasks. The energy-efficient new technology, which is capable of enhanced computational power and speed, can potentially be used in edge computing, as well as handheld devices and applications with limited power resource.
“This work is a significant breakthrough in our quest to design low-energy computing. The idea of using multiple switching in a single element draws inspiration from how the brain works and fundamentally reimagines the design strategy of a logic circuit,” said Associate Professor Ariando from the NUS Department of Physics who led the research.
The research was first published in the journal Nature on 1 September 2021, and carried out in collaboration with the Indian Association for the Cultivation of Science, Hewlett Packard Enterprise, the University of Limerick, the University of Oklahoma, and Texas A&M University.
“This new discovery can contribute to developments in edge computing as a sophisticated in-memory computing approach to overcome the von Neumann bottleneck, a delay in computational processing seen in many digital technologies due to the physical separation of memory storage from a device’s processor,” said Assoc Prof Ariando. The new molecular device also has the potential to contribute to designing next generation processing chips with enhanced computational power and speed.
“Similar to the flexibility and adaptability of connections in the human brain, our memory device can be reconfigured on the fly for different computational tasks by simply changing applied voltages. Furthermore, like how nerve cells can store memories, the same device can also retain information for future retrieval and processing,” said first author Dr Sreetosh Goswami, Research Fellow from the Department of Physics at NUS.
Research team member Dr Sreebrata Goswami, who was a Senior Research Scientist at NUS and previously Professor at the Indian Association for the Cultivation of Science, conceptualised and designed a molecular system belonging to the chemical family of phenyl azo pyridines that have a central metal atom bound to organic molecules called ligands. “These molecules are like electron sponges that can offer as many as six electron transfers resulting in five different molecular states. The interconnectivity between these states is the key behind the device’s reconfigurability,” explained Dr Sreebrata Goswami.
Dr Sreetosh Goswami created a tiny electrical circuit consisting a 40-nanometer layer of molecular film sandwiched between a top layer of gold, and a bottom layer of gold-infused nanodisc and indium tin oxide. He observed an unprecedented current-voltage profile upon applying a negative voltage to the device. Unlike conventional metal-oxide memristors that are switched on and off at only one fixed voltage, these organic molecular devices could switch between on-off states at several discrete sequential voltages.
Using an imaging technique called Raman spectroscopy, spectral signatures in the vibrational motion of the organic molecule were observed to explain the multiple transitions. Dr Sreebrata Goswami explained, “Sweeping the negative voltage triggered the ligands on the molecule to undergo a series of reduction, or electron-gaining which caused the molecule to transition between off and on states.”
The researchers described the behavior of the molecules using a decision tree algorithm with “if-then-else” statements, which is used in the coding of several computer programs, particularly digital games, as compared to the conventional approach of using basic physics-based equations.
New possibilities for energy-efficient devices
Building on their research, the team used the molecular memory devices to run programs for different real-world computational tasks. As a proof of concept, the team demonstrated that their technology could perform complex computations in a single step, and could be reprogrammed to perform another task in the next instant. An individual molecular memory device could perform the same computational functions as thousands of transistors, making the technology a more powerful and energy-efficient memory option.
“The technology might first be used in handheld devices, like cell phones and sensors, and other applications where power is limited,” added Assoc Prof Ariando.
The team in the midst of building new electronic devices incorporating their innovation, and working with collaborators to conduct simulation and benchmarking relating to existing technologies.
Other contributors to the research paper include Abhijeet Patra and Santi Prasad Rath from NUS, Rajib Pramanick from the Indian Association for the Cultivation of Science, Martin Foltin from Hewlett Packard Enterprise, Damien Thompson from the University of Limerick, T. Venkatesan from the University of Oklahoma, and R. Stanley Williams from Texas A&M University.
Here’s a link to and a citation for the paper,
Decision trees within a molecular memristor by Sreetosh Goswami, Rajib Pramanick, Abhijeet Patra, Santi Prasad Rath, Martin Foltin, A. Ariando, Damien Thompson, T. Venkatesan, Sreebrata Goswami & R. Stanley Williams. Nature volume 597, pages 51–56 (2021) DOI: https://doi.org/10.1038/s41586-021-03748-0 Published 01 September 2021 Issue Date 02 September 2021
So far the researchers aren’t trying to power anything with tears but they have discovered that tears could be used to generate electricity (from an Oct. 2, 2017 news item on phys.org),
A team of Irish scientists has discovered that applying pressure to a protein found in egg whites and tears can generate electricity. The researchers from the Bernal Institute, University of Limerick (UL), Ireland, observed that crystals of lysozyme, a model protein that is abundant in egg whites of birds as well as in the tears, saliva and milk of mammals can generate electricity when pressed. Their report is published today (October 2) in the journal, Applied Physics Letters.
The ability to generate electricity by applying pressure, known as direct piezoelectricity, is a property of materials such as quartz that can convert mechanical energy into electrical energy and vice versa. Such materials are used in a variety of applications ranging from resonators and vibrators in mobile phones to deep ocean sonars and ultrasound imaging. Bone, tendon and wood are long known to possess piezoelectricity.
“While piezoelectricity is used all around us, the capacity to generate electricity from this particular protein had not been explored. The extent of the piezoelectricity in lysozyme crystals is significant. It is of the same order of magnitude found in quartz. However, because it is a biological material, it is non toxic so it could have many innovative applications such as electroactive anti-microbial coatings for medical implants,” explained Aimee Stapleton, the lead author and an Irish Research Council EMBARK Postgraduate Fellow in the Department of Physics and Bernal Institute of UL.
Crystals of lysozyme are easy to make from natural sources. “The high precision structure of lysozyme crystals has been known since 1965,” said structural biologist at UL and co-author Professor Tewfik Soulimane.
“In fact, it is the second protein structure and the first enzyme structure that was ever solved,” he added, “but we are the first to use these crystals to show the evidence of piezoelectricity”.
According to team leader Professor Tofail Syed of UL’s Department of Physics, “Crystals are the gold-standard for measuring piezoelectricity in non-biological materials. Our team has shown that the same approach can be taken in understanding this effect in biology. This is a new approach as scientists so far have tried to understand piezoelectricity in biology using complex hierarchical structures such as tissues, cells or polypeptides rather than investigating simpler fundamental building blocks”.
The discovery may have wide reaching applications and could lead to further research in the area of energy harvesting and flexible electronics for biomedical devices. Future applications of the discovery may include controlling the release of drugs in the body by using lysozyme as a physiologically mediated pump that scavenges energy from its surroundings. Being naturally biocompatible and piezoelectric, lysozyme may present an alternative to conventional piezoelectric energy harvesters, many of which contain toxic elements such as lead.
Professor Luuk van der Wielen, Director of Bernal Institute and Bernal Professor of Biosystems Engineering and Design expressed his delight at this breakthrough by UL scientists.
“The €109-million Bernal Institute has the ambition to impact the world on the basis of top science in an increasingly international context. The impact of this discovery in the field of biological piezoelectricity will be huge and Bernal scientists are leading from the front the progress in this field,” he said.