Starting with the “and more” part of the headline, it’s great to have found an article describing Vive Crop’s technology in language I can understand, Sadly, I failed to see it until Dec. 26, 2013,. Titled “Vive La Crop! nanotech venture vive crop protection of toronto has developed a more eco-friendly way to keep pests, fungi and weeds out of farmers’ fields. and that’s just the beginning,” is written by Tyler Hamilton for the April 2012 issue of ACCN the Canadian Chemical News (L’Actualite chemique canadienne) and it answers many of the questions I’ve had about Vive Crop’s Allosperse technology,
Pesticides don’t have the best reputation when it comes to their potential impacts on human health, but even more concerning — for regulators especially — are the volatile organic solvents frequently relied on to deliver crop-protection chemicals to farmers’ fields.
The solvents themselves are often known carcinogens, not the kind of thing we want on farmland that grows soy, corn and wheat. And they’re not as effective as they could be. Farmers tend to overspray to make sure enough of the active ingredients in insecticides, fungicides and herbicides are dispersed across a field to be effective.
It’s why Vive Crop Protection, a Toronto-based nanotechnology company specializing in crop protection, has been attracting so much attention from some of the world’s biggest chemical companies. Vive Crop (formerly Vive Nano, and before that Northern Nanotechnologies) has done away with the need for volatile organic solvents.
At the heart of Vive Crop’s technology are polymer particles the company has trademarked under the name Allosperse, which measure less than 10 nanometres in size. It describes these particles as ultra- small cages — or “really tiny little FEDEX boxes” in the words of CEO [Chief Executive Officer] Keith Thomas — which hold active pesticide ingredients and are engineered to disperse evenly in water.
Even and thorough dispersal is critical. Avinash Bhaskar, an analyst at research firm Frost & Sullivan who has followed Vive Crop closely, says one of the biggest problems with pesticides is they tend to agglomerate, resulting in uneven, clustery distribution on fields. “You want uniform distribution on the soil,” Bhaskar says. “Vive Crop’s technology prevents agglomeration and this is a key differentiator in the market.”
How Vive Crop chemically engineers these Allosperse particles is the company’s core innovation. It starts by dissolving negatively charged polymers in water. The like charges repel so the polymers spread out in the solution. Then positively charged ions are added to the mix. These ions neutralize the charge around the polymers, causing the polymers to collapse around the ions and create a kind of nanocage — the Allosperse.
The company then filters out the positive and negative ions and loads up the empty cages with molecules of active pesticide ingredients. The cage itself is amphiphilic, meaning it has both water-attracting and water-repelling areas. In this case, the outer shell attracts water and the inner core doesn’t. “While in water the active ingredient, which also hates water, stays inside (the cages),” explains Vive Crop chief technology officer Darren Anderson. Because the outside of the cages like water, the particles freely and evenly disperse. “Once sprayed on the crop, the water droplets evaporate and the active ingredient gradually disperses from the particles that are left behind.” How does Vive Crop assure that the Allosperse cages are amphiphilic? “I can’t tell you the answer,” says Anderson. “It’s part of our secret sauce.”
What the company can say is that the polymer cages themselves are benign. Vive Crop makes them out of chitosans, found naturally in the shells of shrimp and other crustaceans, and polyacrylic acid, the super-absorbent material found in baby diapers.
Interestingly, the core technology appears to be based on a former student project,
The core technology was developed in the early 2000s by Jordan Dinglasan, a chemistry student from the Philippines who took up graduate studies at the University of Toronto. Dinglasan and fellow researchers at U of T’s Department of Chemistry, including Anderson and chemistry professor Cynthia Goh, decided in 2006 that they wanted to reach beyond the walls of academia and create a company to commercialize the technology.
At the time of the Hamilton article, the company had 30 employees. Since the April 2012 article, the company has been busy as I’ve written an Aug. 7, 2013 posting about the US Environmental Protection Agency’s (EPA) approval of Vive Crop’s VCP-01, Bifenthrin 10 DF insecticide for foliar use on crops, turf, and ornamentals. and a September 25, 2013 posting about funding for two Vive Crop projects from Sustainable Development Technology Canada.
Now in the last weeks of December 2013 Vive Crop has issued two more news releases. First, there’s the Dec. 17, 2013 Vive Crop news release announcing a marketing initiative with a US company, AMVAC Chemical Corporation, which is wholly owned by American Vanguard Corporation and is based in California,,
Vive Crop Protection, Inc. and AMVAC Chemical Corporation are pleased to announce a collaboration to develop and market an advanced insecticide formulation for multiple uses in the United States. The products leverage Vive’s patented AllosperseT technology delivering enhanced agronomic performance and new application opportunities to AMVAC’s customers.
“We are quite excited about working with AMVAC to add to their portfolio of innovative products,” said Vive CEO Keith Thomas. “Vive is rapidly developing a strong pipeline of effective crop protection products for our partners and growers.”
“As part of AMVAC’s continued commitment to innovate and deliver products with the best technology available, we are very pleased to be working with and investigating this new technology from Vive” said AMVAC Eric Wintemute, CEO of AMVAC .
Vive Crop followed up with a Dec. 19, 2013 news release announcing another marketing initiative, this time with United Suppliers (based in Iowa, US),
United Suppliers, Inc. and Vive Crop Protection, Inc. are pleased to announce a collaboration to demonstrate and market advanced formulation technologies in the United States. Targeted to launch in the 2015 growing season, these technologies will leverage Vive’s patented AllosperseT delivery system to provide enhanced agronomic performance and new application opportunities to United Suppliers’ leading-edge owners and customers.
“We are pursuing the capabilities of getting more activity out of the products we are using in current and expanded applications,” said United Suppliers VP of Crop Protection and Seed Brett Bruggeman. “United Suppliers’ retail owners are in the best position to deliver new technology to growers.”
“We are quite excited about working with United Suppliers to provide innovative products to their customers,” said Vive CEO Keith Thomas. “Vive is rapidly developing a strong pipeline of effective crop protection products for our partners and growers.”
About United Suppliers
United Suppliers is a unique, customer-owned wholesale supplier of crop protection inputs, seed and crop nutrients, with headquarters in Eldora and Ames, Iowa. Founded in 1963, United Suppliers is today comprised of more than 650 agricultural retailers (Owners) who operate nearly 2,800 retail locations throughout the United States and parts of Canada. The mission of United Suppliers is to be the supplier of choice while increasing its Owners’ capabilities and competitiveness. To meet this goal, United Suppliers strives to provide Owners with transparent market intelligence, innovative products, reliable market access and customized business solutions. For more information, please visit www.unitedsuppliers.com.
About Vive Crop Protection
Vive Crop Protection makes products that better protect crops from pests. The company has won a number of awards and was highly commended for Best Formulation Innovation at the 2012 Agrow Awards. Vive’s patented Allosperse delivery system has the ability to coat plants more evenly, which provides better crop protection and can lead to increased yields. Vive is working with partners across the globe that share our vision of bringing safer, more effective crop protection products to growers everywhere. For more information, see www.vivecrop.com.
I wish Vive Crop all the best in 2014 as it capitalizes on the momentum it seems to be building.