Tag Archives: Sarah Collins

Robot skin that feels heat, pain, and pressure

This June 17, 2025 news item on ScienceDaily announces research into developing robot skin that more closely mimics skin (human and otherwise),

Scientists have developed a low-cost, durable, highly-sensitive robotic ‘skin’ that can be added to robotic hands like a glove, enabling robots to detect information about their surroundings in a way that’s similar to humans.

The researchers, from the University of Cambridge and University College London (UCL), developed the flexible, conductive skin, which is easy to fabricate and can be melted down and formed into a wide range of complex shapes. The technology senses and processes a range of physical inputs, allowing robots to interact with the physical world in a more meaningful way.

A June 11, 2025 University of Cambridge news release (also on EurekAlert) by Sarah Collins, which originated the news item, describes what makes this work a breakthrough,

Unlike other solutions for robotic touch, which typically work via sensors embedded in small areas and require different sensors to detect different types of touch, the entirety of the electronic skin developed by the Cambridge and UCL researchers is a sensor, bringing it closer to our own sensor system: our skin.  

Although the robotic skin is not as sensitive as human skin, it can detect signals from over 860,000 tiny pathways in the material, enabling it to recognise different types of touch and pressure – like the tap of a finger, a hot or cold surface, damage caused by cutting or stabbing, or multiple points being touched at once – in a single material.

The researchers used a combination of physical tests and machine learning techniques to help the robotic skin ‘learn’ which of these pathways matter most, so it can sense different types of contact more efficiently.

In addition to potential future applications for humanoid robots or human prosthetics where a sense of touch is vital, the researchers say the robotic skin could be useful in industries as varied as the automotive sector or disaster relief. The results are reported in the journal Science Robotics.

Electronic skins work by converting physical information – like pressure or temperature – into electronic signals. In most cases, different types of sensors are needed for different types of touch – one type of sensor to detect pressure, another for temperature, and so on – which are then embedded into soft, flexible materials. However, the signals from these different sensors can interfere with each other, and the materials are easily damaged.

“Having different sensors for different types of touch leads to materials that are complex to make,” said lead author Dr David Hardman from Cambridge’s Department of Engineering. “We wanted to develop a solution that can detect multiple types of touch at once, but in a single material.”

“At the same time, we need something that’s cheap and durable, so that it’s suitable for widespread use,” said co-author Dr Thomas George Thuruthel from UCL.

Their solution uses one type of sensor that reacts differently to different types of touch, known as multi-modal sensing. While it’s challenging to separate out the cause of each signal, multi-modal sensing materials are easier to make and more robust.

The researchers melted down a soft, stretchy and electrically conductive gelatine-based hydrogel, and cast it into the shape of a human hand. They tested a range of different electrode configurations to determine which gave them the most useful information about different types of touch. From just 32 electrodes placed at the wrist, they were able to collect over 1.7 million pieces of information over the whole hand, thanks to the tiny pathways in the conductive material.

The skin was then tested on different types of touch: the researchers blasted it with a heat gun, pressed it with their fingers and a robotic arm, gently touched it with their fingers, and even cut it open with a scalpel. The team then used the data gathered during these tests to train a machine learning model so the hand would recognise what the different types of touch meant. 

“We’re able to squeeze a lot of information from these materials – they can take thousands of measurements very quickly,” said Hardman, who is a postdoctoral researcher in the lab of co-author Professor Fumiya Iida. “They’re measuring lots of different things at once, over a large surface area.”

“We’re not quite at the level where the robotic skin is as good as human skin, but we think it’s better than anything else out there at the moment,” said Thuruthel. “Our method is flexible and easier to build than traditional sensors, and we’re able to calibrate it using human touch for a range of tasks.”

In future, the researchers are hoping to improve the durability of the electronic skin, and to carry out further tests on real-world robotic tasks.

The research was supported by Samsung Global Research Outreach Program, the Royal Society, and the Engineering and Physical Sciences Research Council (EPSRC), part of UK Research and Innovation (UKRI). Fumiya Iida is a Fellow of Corpus Christi College, Cambridge.

Here’s a link to and a citation for the paper,

Multimodal information structuring with single-layer soft skins and high-density electrical impedance tomography by David Hardman, Thomas George Thuruthel, and Fumiya Iida. Science Robotics 11 Jun 2025 Vol 10, Issue 103 DOI: 10.1126/scirobotics.adq2303

This paper is behind a paywall.

Biohybrid device (a new type of neural implant) could restore limb function

A March 23, 2023 news item on ScienceDaily announces a neural implant that addresses failures due to scarring issues,

Researchers have developed a new type of neural implant that could restore limb function to amputees and others who have lost the use of their arms or legs.

In a study carried out in rats, researchers from the University of Cambridge used the device to improve the connection between the brain and paralysed limbs. The device combines flexible electronics and human stem cells — the body’s ‘reprogrammable’ master cells — to better integrate with the nerve and drive limb function.

Previous attempts at using neural implants to restore limb function have mostly failed, as scar tissue tends to form around the electrodes over time, impeding the connection between the device and the nerve. By sandwiching a layer of muscle cells reprogrammed from stem cells between the electrodes and the living tissue, the researchers found that the device integrated with the host’s body and the formation of scar tissue was prevented. The cells survived on the electrode for the duration of the 28-day experiment, the first time this has been monitored over such a long period.

A March 22, 2023 University of Cambridge press release (also on EurekAlert but published March 23, 2023) by Sarah Collins, delves further into the topic,

The researchers say that by combining two advanced therapies for nerve regeneration – cell therapy and bioelectronics – into a single device, they can overcome the shortcomings of both approaches, improving functionality and sensitivity.

While extensive research and testing will be needed before it can be used in humans, the device is a promising development for amputees or those who have lost function of a limb or limbs. The results are reported in the journal Science Advances.

A huge challenge when attempting to reverse injuries that result in the loss of a limb or the loss of function of a limb is the inability of neurons to regenerate and rebuild disrupted neural circuits.

“If someone has an arm or a leg amputated, for example, all the signals in the nervous system are still there, even though the physical limb is gone,” said Dr Damiano Barone from Cambridge’s Department of Clinical Neurosciences, who co-led the research. “The challenge with integrating artificial limbs, or restoring function to arms or legs, is extracting the information from the nerve and getting it to the limb so that function is restored.”

One way of addressing this problem is implanting a nerve in the large muscles of the shoulder and attaching electrodes to it. The problem with this approach is scar tissue forms around the electrode, plus it is only possible to extract surface-level information from the electrode.

To get better resolution, any implant for restoring function would need to extract much more information from the electrodes. And to improve sensitivity, the researchers wanted to design something that could work on the scale of a single nerve fibre, or axon.

“An axon itself has a tiny voltage,” said Barone. “But once it connects with a muscle cell, which has a much higher voltage, the signal from the muscle cell is easier to extract. That’s where you can increase the sensitivity of the implant.”

The researchers designed a biocompatible flexible electronic device that is thin enough to be attached to the end of a nerve. A layer of stem cells, reprogrammed into muscle cells, was then placed on the electrode. This is the first time that this type of stem cell, called an induced pluripotent stem cell, has been used in a living organism in this way.

“These cells give us an enormous degree of control,” said Barone. “We can tell them how to behave and check on them throughout the experiment. By putting cells in between the electronics and the living body, the body doesn’t see the electrodes, it just sees the cells, so scar tissue isn’t generated.”

The Cambridge biohybrid device was implanted into the paralysed forearm of the rats. The stem cells, which had been transformed into muscle cells prior to implantation, integrated with the nerves in the rat’s forearm. While the rats did not have movement restored to their forearms, the device was able to pick up the signals from the brain that control movement. If connected to the rest of the nerve or a prosthetic limb, the device could help restore movement.

The cell layer also improved the function of the device, by improving resolution and allowing long-term monitoring inside a living organism. The cells survived through the 28-day experiment: the first time that cells have been shown to survive an extended experiment of this kind.

The researchers say that their approach has multiple advantages over other attempts to restore function in amputees. In addition to its easier integration and long-term stability, the device is small enough that its implantation would only require keyhole surgery. Other neural interfacing technologies for the restoration of function in amputees require complex patient-specific interpretations of cortical activity to be associated with muscle movements, while the Cambridge-developed device is a highly scalable solution since it uses ‘off the shelf’ cells.

In addition to its potential for the restoration of function in people who have lost the use of a limb or limbs, the researchers say their device could also be used to control prosthetic limbs by interacting with specific axons responsible for motor control.

“This interface could revolutionise the way we interact with technology,” said co-first author Amy Rochford, from the Department of Engineering. “By combining living human cells with bioelectronic materials, we’ve created a system that can communicate with the brain in a more natural and intuitive way, opening up new possibilities for prosthetics, brain-machine interfaces, and even enhancing cognitive abilities.”

“This technology represents an exciting new approach to neural implants, which we hope will unlock new treatments for patients in need,” said co-first author Dr Alejandro Carnicer-Lombarte, also from the Department of Engineering.

“This was a high-risk endeavour, and I’m so pleased that it worked,” said Professor George Malliaras from Cambridge’s Department of Engineering, who co-led the research. “It’s one of those things that you don’t know whether it will take two years or ten before it works, and it ended up happening very efficiently.”

The researchers are now working to further optimise the devices and improve their scalability. The team have filed a patent application on the technology with the support of Cambridge Enterprise, the University’s technology transfer arm.

The technology relies on opti-oxTM enabled muscle cells. opti-ox is a precision cellular reprogramming technology that enables faithful execution of genetic programmes in cells allowing them to be manufactured consistently at scale. The opti-ox enabled muscle iPSC cell lines used in the experiment were supplied by the Kotter lab [Mark Kotter] from the University of Cambridge. The opti-ox reprogramming technology is owned by synthetic biology company bit.bio.

The research was supported in part by the Engineering and Physical Sciences Research Council (EPSRC), part of UK Research and Innovation (UKRI), Wellcome, and the European Union’s Horizon 2020 Research and Innovation Programme.

Caption: In a study carried out in rats, researchers from the University of Cambridge used a biohybrid device to improve the connection between the brain and paralysed limbs. The device combines flexible electronics and human stem cells – the body’s ‘reprogrammable’ master cells – to better integrate with the nerve and drive limb function. Credit: University of Cambirdge

Here’s a link to and a citation for the paper,

Functional neurological restoration of amputated peripheral nerve using biohybrid regenerative bioelectronics by Amy E. Rochford, Alejandro Carnicer-Lombarte, Malak Kawan, Amy Jin, Sam Hilton, Vincenzo F. Curto, Alexandra L. Rutz, Thomas Moreau, Mark R. N. Kotter, George G. Malliaras, and Damiano G. Barone. Science Advances 22 Mar 2023 Vol 9, Issue 12 DOI: 10.1126/sciadv.add8162

This paper is open access.

The synthetic biology company mentioned in the press release, bit.bio is here