Monthly Archives: January 2013

Call for nominations: US National Academies Communication Awards

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The Jan. 16, 2013 press release from US National Academies announced a call for nominations for communication in various media including books, film/radio/tv, magazine/newspaper, and online materials that have been published in the US,

The Keck Futures Initiative—a program of the National Academy of Sciences, National Academy of Engineering, and Institute of Medicine, with the support of the W. M. Keck Foundation—will award $20,000 prizes to individuals or teams who have developed creative, original work that addresses issues and advances in science, engineering and/or medicine for the general public. Nominations are accepted in four categories: Book; Film/Radio/TV; Magazine/Newspaper; and Online.

ELIGIBILITY
To be considered for a 2013 Communication Award, the work should:

  • be accessible and appeal to a broad, public audience;
  • demonstrate clarity, creativity, originality, and accuracy;
  • address issues and/or advances in science, engineering, and/or medicine;
  • cover topics that have an impact on society; and
  • have been published, broadcast, or released in 2012, in the United States and in English.

Call For Nominations Now Being Accepted
Nominations will be accepted through February 8, 2013.  For more information about the process, please visit: http://www.keckfutures.org/awards/nominate.html.

NOMINATION FORM
Nominations must be submitted on the online nomination form at http://www.keckfutures.org/awards/nominate.html. Copies of the nominated work must be submitted as described for each category.  Self nominations are permitted. Please submit a nomination in the category that most closely fits the work(s) being nominated.  Supporting materials will not be returned. There is no nomination fee.

BOOK
Books must have been published in the U.S. in 2012 to be considered. Please submit two copies of the book. The publisher and year of publication must be printed on the book. Advance publication dates must include verification from the publisher.

FILM/RADIO/TV
Submissions must have aired on a U.S. station or have been released in U.S. theaters or on DVD in 2012 and may include a single story or movie, a series, or as many as six brief, unrelated stories. Please submit three CDs or DVDs labeled with the nominee’s name(s), the title(s) included on the DVD or CD, and the original airdate (with the name of the U.S. station and the program on which the stories aired) or release date. These must be submitted in protective cases and include authorization allowing the Keck Futures Initiative to reproduce the CD or DVD for review purposes (copyright release). Submission of copies of the program transcript is also encouraged. If you are not able to provide copyright release, please submit an additional 20 copies of the CD or DVD.

MAGAZINE/NEWSPAPER
Work in this category must have been published in the U.S. in 2012, and may comprise a single article or as many as four articles that are unrelated or that constitute a formal series. Please submit three original copies of each article clearly showing the byline and the name and date of the publication and authorization allowing the Keck Futures Initiative to reproduce the article for review purposes (copyright release). If you are not able to provide copyright release, please send an additional 20 copies of the article(s), or a PDF file of the article(s).

ONLINE
Work created specifically for the Web must have been posted online in 2012. Entries may include as many as six online articles, hypertext documents, podcasts, commentaries, etc., or any combination thereof. Preference will be given to nominations that make the best use of the medium, including multi-media presentations that incorporate a combination of videos, blog entries, interactive features, and/or other capabilities unique to this communication medium. Include links to the unique URLs for each work(s). Links, must be active through October 31, 2013.

2013 TIMELINE

  • February 8 – Nomination process closes.
  • Fall 2013 – Winners honored at a ceremony to be held in Washington D.C. Date TBD.

All nominations must be submitted online by February 8, and all supporting materials must be received by February 15, 2013.

For More Information
Visit www.keckfutures.org/awards for a complete listing of this year’s Selection Committee, information about the awards and to nominate.

I wonder if I could self-nominate, despite the fact that I self-identify as a Canadian science blogger; this blog is hosted by a US company. Does that constitute publication in the US? That $20,000 prize is tempting. Good luck to all who enter the competition.

Virtual lego used to simulate self-assembling crystal structures

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The Jan. 17, 2013 news release on EurekAlert describes a ‘soft’ or virtual lego computer simulation developed at the University of Vienna (Austria),

In developing these novel self-assembling materials, postdoc Barbara Capone has focused on the design of organic and inorganic building blocks, which are robust and can be produced at large scale. Capone has put forward, together with her colleagues at the Universities of Vienna and Mainz, a completely new pathway for the construction of building blocks at the nanoscale.

…

The team of researchers has shown that so-called block copolymer stars – that means polymers that consist of two different blocks and they are chemically anchored on a common point – have a robust and flexible architecture and they possess the ability to self-assemble at different levels. At the single-molecule level, they first order as soft patchy colloids which serve then as “soft Lego” for the emergence of larger structures. At the next level of self-assembly, the colloids form complex crystal structures, such as diamond or cubic phases.

The spatial ordering in the crystals can be steered through the architecture of the “soft Lego” and opens up the possibility for the construction of new materials at the macroscopic scale with desired structure. In this way, crystals can be built that have applications in, e.g., photonics, acting as filters for light of certain frequencies or as light guides.

You can find illustrations of the ‘diamond’ and the ‘cube’ produced by Capone and her colleagues with the news release on EurekAlert or here at the University of Vienna’s media portal where you may be able to find more information if you can read German. Alternatively, you can read the research paper,

Telechelic Star Polymers as Self-Assembling Units from the Molecular to the Macroscopic Scale by Barbara Capone, Ivan Coluzza, Federica LoVerso, Christos N. Likos, and Ronald Blaak in Physical Review Letters 109 [issue no. 23], 238301 (2012) [5 pages]DOI:10.1103/PhysRevLett.109.238301

This article is behind a paywall.

A ‘wandering meatloaf’ with teeth inspires nanomaterials for solar cells and Li-ion batteries

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The ‘wandering meatloaf’ is a species of marine snail (or chiton) that has extraordinary teeth according to the Jan. 16, 2013 news item on ScienceDaily,

An assistant professor [David Kisailus] at the University of California, Riverside’s Bourns College of Engineering is using the teeth of a marine snail found off the coast of California to create less costly and more efficient nanoscale materials to improve solar cells and lithium-ion batteries.

…

The paper is focused on the gumboot chiton, the largest type of chiton, which can be up to a foot-long. They are found along the shores of the Pacific Ocean from central California to Alaska. They have a leathery upper skin, which is usually reddish-brown and occasionally orange, leading some to give it the nickname “wandering meatloaf.”

Over time, chitons have evolved to eat algae growing on and within rocks using a specialized rasping organ called a radula, a conveyer belt-like structure in the mouth that contains 70 to 80 parallel rows of teeth. During the feeding process, the first few rows of the teeth are used to grind rock to get to the algae. They become worn, but new teeth are continuously produced and enter the “wear zone” at the same rate as teeth are shed.

The University of California Riverside Jan. 15, 2013 news release by Sean Nealon, which originated the news item, describes the chiton’s teeth and the specifics of Kisailus’ inspiration (Note: A link has been removed),

Over time, chitons have evolved to eat algae growing on and within rocks using a specialized rasping organ called a radula, a conveyer belt-like structure in the mouth that contains 70 to 80 parallel rows of teeth. During the feeding process, the first few rows of the teeth are used to grind rock to get to the algae. They become worn, but new teeth are continuously produced and enter the “wear zone” at the same rate as teeth are shed.

Kisailus, who uses nature as inspiration to design next generation engineering products and materials, started studying chitons five years ago because he was interested in abrasion and impact-resistant materials. He has previously determined that the chiton teeth contain the hardest biomineral known on Earth, magnetite, which is the key mineral that not only makes the tooth hard, but also magnetic.

…

Kisailus is using the lessons learned from this biomineralization pathway as inspiration in his lab to guide the growth of minerals used in solar cells and lithium-ion [li-ion] batteries. By controlling the crystal size, shape and orientation of engineering nanomaterials, he believes he can build materials that will allow the solar cells and lithium-ion batteries to operate more efficiently. In other words, the solar cells will be able to capture a greater percentage of sunlight and convert it to electricity more efficiently and the lithium-ion batteries could need significantly less time to recharge.

Using the chiton teeth model has another advantage: engineering nanocrystals can be grown at significantly lower temperatures, which means significantly lower production costs.

While Kisailus is focused on solar cells and lithium-ion batteries, the same techniques could be used to develop everything from materials for car and airplane frames to abrasion resistant clothing. In addition, understanding the formation and properties of the chiton teeth could help to create better design parameters for better oil drills and dental drill bits.

Here’s a representation of the teeth from the University of California Riverside,

A series of images that show the teeth of the gumboot chiton (aka, snail, aka, wandering meatloaf)

A series of images that show the teeth of the gumboot chiton (aka, snail, aka, wandering meatloaf)

You can find other images and media materials in the ScienceDaily news item or the University of California Riverside news release. This citation and link for the research paper is from the ScienceDaily news item,

Qianqian Wang, Michiko Nemoto, Dongsheng Li, James C. Weaver, Brian Weden, John Stegemeier, Krassimir N. Bozhilov, Leslie R. Wood, Garrett W. Milliron, Christopher S. Kim, Elaine DiMasi, David Kisailus. Phase Transformations and Structural Developments in the Radular Teeth ofCryptochiton Stelleri. Advanced Functional Materials, 2013; DOI: 10.1002/adfm.201202894

This article is behind a paywall.

Graphene and its grain boundaries

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Most folks who follow the graphene scene are familiar with the honeycomb structure (hexagonal network) shown in diagram after diagram but I imagine there’s more than one of us who didn’t realize that defects can occur at the boundaries, from the Jan. 15, 2012 news release on EurekAlert,

When graphene is grown, lattices of the carbon grains are formed randomly, linked together at different angles of orientation in a hexagonal network. However, when those orientations become misaligned during the growth process, defects called grain boundaries (GBs) form. These boundaries scatter the flow of electrons in graphene, a fact that is detrimental to its successful electronic performance.

The Jan. 14, 2013 University of Illinois Beckman Institute news release written by Steve McGoughey, which originated the item on  EurekAlert, provides insight into the problem and its solution,

Beckman Institute researchers Joe Lyding and Eric Pop and their research groups have now given new insight into the electronics behavior of graphene with grain boundaries that could guide fabrication methods toward lessening their effect. The researchers grew polycrystalline graphene by chemical vapor deposition (CVD), using scanning tunneling microscopy (STM) and spectroscopy for analysis, to examine at the atomic scale grain boundaries on a silicon wafer. They reported their results in the journal ACS Nano.

“We obtained information about electron scattering at the boundaries that shows it significantly limits the electronic performance compared to grain boundary free graphene,” Lyding said. “Grain boundaries form during graphene growth by CVD, and, while there is much worldwide effort to minimize the occurrence of grain boundaries, they are a fact of life for now.

“For electronics you would want to be able to make it on a wafer scale. Boundary free graphene is a key goal. In the interim we have to live with the grain boundaries, so understanding them is what we’re trying to do.”

Lyding compared graphene lattices made with the CVD method to pieces of a cyclone fence.

“If you had two pieces of fence, and you laid them on the ground next to each other but they weren’t perfectly aligned, then they wouldn’t match,” he said. “That’s a grain boundary, where the lattice doesn’t match.”

…

Their analysis showed that when the electrons’ itinerary takes them to a grain boundary, it is like, Lyding said, hitting a hill.

“The electrons hit this hill, they bounce off, they interfere with themselves and you actually see a standing wave pattern,” he said. “It’s a barrier so they have to go up and over that hill. Like anything else, that is going to slow them down. That’s what Justin was able to measure with these spectroscopy measurements.

“Basically a grain boundary is a resistor in series with a conductor. That’s always bad. It means it’s going to take longer for an electron to get from point A to point B with some voltage applied.”

…

In the paper, the researchers were able to report on their analysis of the orientation angles between pieces of graphene as they grew together, and found “no preferential orientation angle between grains, and the GBs are continuous across graphene wrinkles and Si02 topography.” They reported that analysis of those patterns “indicates that backscattering and intervalley scattering are the dominant mechanisms responsible for the mobility reduction in the presence of GBs in CVD-grown graphene.”

…

The researchers work is aimed not just at understanding, but also at controlling grain boundaries. One of their findings – that GBs are aperiodic – replicated other work and could have implications for controlling them, as they wrote in the paper: “Combining the spectroscopic and scattering results suggest that GBs that are more periodic and well-ordered lead to reduced scattering from the GBs.”

“I think if you have to live with grain boundaries you would like to be able to control exactly what their orientation is and choose an angle that minimizes the scattering,” Lyding said.

Here’s a citation and link for the article,

Atomic-Scale Evidence for Potential Barriers and Strong Carrier Scattering at Graphene Grain Boundaries: A Scanning Tunneling Microscopy Study by Justin C. Koepke, Joshua D. Wood, David Estrada, Zhun-Yong Ong, Kevin T. He, Eric Pop, and Joseph W. Lyding in ACS Nano, Article ASAP DOI: 10.1021/nn302064p Publication Date (Web): December 13, 2012

Copyright © 2012 American Chemical Society

The article has not been published in print and it is behind a paywall.

The yin and the yang of carbon nanotubes and toxicity

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Illustration courtesy of the University College of London (UCL). Downloaded from http://www.ucl.ac.uk/news/news-articles/0113/130115-chemistry-resolves-toxic-concerns-about-carbon-nanotubes

Illustration courtesy of the University College of London (UCL). Downloaded from http://www.ucl.ac.uk/news/news-articles/0113/130115-chemistry-resolves-toxic-concerns-about-carbon-nanotubes

Researchers at the University College of London (UCL), France’s Centre national de la recherche scientifique (CNRS), and Italy’s University of Trieste have determined that carbon nanotube toxicity issues can be addressed be reducing their length and treating them chemically. From the Jan. 15,2013 news item on ScienceDaily,

In a new study, published January 15 [2013] in the journal Angewandte Chemie, evidence is provided that the asbestos-like reactivity and pathogenicity reported for long, pristine nanotubes can be completely alleviated if their surface is modified and their effective length is reduced as a result of chemical treatment.

First atomically described in the 1990s, carbon nanotubes are sheets of carbon atoms rolled up into hollow tubes just a few nanometres in diameter. Engineered carbon nanotubes can be chemically modified, with the addition of chemotherapeutic drugs, fluorescent tags or nucleic acids — opening up applications in cancer and gene therapy.

Furthermore, these chemically modified carbon nanotubes can pierce the cell membrane, acting as a kind of ‘nano-needle’, allowing the possibility of efficient transport of therapeutic and diagnostic agents directly into the cytoplasm of cells.

Among their downsides however, have been concerns about their safety profile. One of the most serious concerns, highlighted in 2008, involves the carcinogenic risk from the exposure and persistence of such fibres in the body. Some studies indicate that when long untreated carbon nanotubes are injected to the abdominal cavity of mice they can induce unwanted responses resembling those associated with exposure to certain asbestos fibres.

In this paper, the authors describe two different reactions which ask if any chemical modification can render the nanotubes non-toxic. They conclude that not all chemical treatments alleviate the toxicity risks associated with the material. Only those reactions that are able to render carbon nanotubes short and stably suspended in biological fluids without aggregation are able to result in safe, risk-free material.

Here’s a citation and link for this latest  research, from the ScienceDaily news item where you can also read the lead researcher’s comments about carbon nanotubes, safety, and unreasonable proposals to halt production,

Hanene Ali-Boucetta, Antonio Nunes, Raquel Sainz, M. Antonia Herrero, Bowen Tian, Maurizio Prato, Alberto Bianco, Kostas Kostarelos. Asbestos-like Pathogenicity of Long Carbon Nanotubes Alleviated by Chemical Functionalization. Angewandte Chemie International Edition, 2013; DOI: 10.1002/anie.201207664

The article is behind a paywall. I have mentioned long carbon nanotubes and their resemblance to asbestos fibres in several posts. The  Oct. 26, 2009 posting [scroll down about 1/3 of the way] highlights research which took place after the study where mice had carbon nanotubes injected into their bellies; in this second piece of research they inhaled the nanotubes.

ETA Jan. 21, 2013: Dexter Johnson gives context and commentary about this latest research into long multiwalled nanotubes (MWNTs) which he sums up as the answer to this question “What if you kept the MWNTs short?”  in a Jan. 18, 2013 posting on his Nanoclast blog (on the IEEE [Institute of Electrical and Electronics Engineers] website)

Researching tweets (the Twitter kind)

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The US Library of Congress, in April 2010, made a deal with Twitter (microblogging service where people chat or tweet in 140 characters) to acquire all the tweets from 2006 to April 2010 and starting from April 2010, all subsequent tweets (the deal is mentioned in my April 15, 2010 posting [scroll down about 60% of the way]). Reading between the lines of the Library of Congress’ Jan. 2013 update/white paper, the job has proved even harder than they originally anticipated,

In April, 2010, the Library of Congress and Twitter signed an agreement providing the Library the public tweets from the company’s inception through the date of the agreement, an archive of tweets from 2006 through April, 2010. Additionally, the Library and Twitter agreed that Twitter would provide all public tweets on an ongoing basis under the same terms. The Library’s first objectives were to acquire and preserve the 2006-10 archive; to establish a secure, sustainable process for receiving and preserving a daily, ongoing stream of tweets through the present day; and to create a structure for organizing the entire archive by date. This month, all those objectives will be completed. To date, the Library has an archive of approximately 170 billion tweets.

The Library’s focus now is on confronting and working around the technology challenges to making the archive accessible to researchers and policymakers in a comprehensive, useful way. It is clear that technology to allow for scholarship access to large data sets is lagging behind technology for creating and distributing such data. Even the private sector has not yet implemented cost-effective commercial solutions because of the complexity and resource requirements of such a task. The Library is now pursuing partnerships with the private sector to allow some limited access capability in our reading rooms. These efforts are ongoing and a priority for the Library. (p. 1)

David Bruggeman in his Jan. 15, 2013 posting about this Library of Congress ‘Twitter project’ provides some mind-boggling numbers,

… That [170 billion tweets] represents the archive Twitter had at the time of the agreement (covering 2006-early 2010) and 150 billion tweets in the subsequent months (the Library receives over half a million new tweets each day, and that number continues to rise).  The archive includes the tweets and relevant metadata for a total of nearly 67 terabytes of data.

Gayle Osterberg, Director of Communications for the Library of Congress writes in a Jan. 4, 2013 posting on the Library of Congress blog about ‘tweet’ archive research issues,

Although the Library has been building and stabilizing the archive and has not yet offered researchers access, we have nevertheless received approximately 400 inquiries from researchers all over the world. Some broad topics of interest expressed by researchers run from patterns in the rise of citizen journalism and elected officials’ communications to tracking vaccination rates and predicting stock market activity.

The white paper/update offers a couple of specific examples of requests,

Some examples of the types of requests the Library has received indicate how researchers might use this archive to inform future scholarship:

* A master’s student is interested in understanding the role of citizens in disruptive events. The student is focusing on real-time micro-blogging of terrorist attacks. The questions focus on the timeliness and accuracy of tweets during specified events.

* A post-doctoral researcher is looking at the language used to spread information about charities’ activities and solicitations via social media during and immediately following natural disasters. The questions focus on audience targets and effectiveness. (p. 4)

At least one of the reasons  no one has received access to the tweets is that a single search of the archived (2006- 2010) tweets alone would take 24 hours,

The Library has assessed existing software and hardware solutions that divide and simultaneously search large data sets to reduce search time, so-called “distributed and parallel computing”. To achieve a significant reduction of search time, however, would require an extensive infrastructure of hundreds if not thousands of servers. This is cost prohibitive and impractical for a public institution.

Some private companies offer access to historic tweets but they are not the free, indexed and searchable access that would be of most value to legislative researchers and scholars.

It is clear that technology to allow for scholarship access to large data sets is not nearly as advanced as the technology for creating and distributing that data. Even the private sector has not yet implemented cost-effective commercial solutions because of the complexity and resource requirements of such a task. (p. 4)

David Bruggeman goes on to suggest that, in an attempt to make the tweets searchable and more easily accessible, all this information could end up behind a paywall (Note: A link has been removed),

I’m reminded of how Ancestry.com managed to get exclusive access to Census records.  While the Bureau benefitted from getting the records digitized, having this taxpayer-paid information controlled by a private company is problematic.

As a Canuck and someone who tweets (@frogheart), I’m not sure how I feel about having my tweets archived by the US Library of Congress in the first place, let alone the possibility I might have to pay for access to my old tweets.

Simon Fraser University completes a successful mating dance while TRIUMF (Canada’s national laboratory for particle and nuclear physics) gets its groove on

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The Federal Government of Canada in the guise of the Canada Foundation for Innovation has just awarded $7.7M to Simon Fraser University (SFU) and its partners for a global innovation hub. From the Jan. 15, 2013 Canada Foundation for Innovation news release,

British Columbia’s research-intensive universities are coming together to create a global hub for materials science and engineering. Simon Fraser University, the University of Victoria, the University of British Columbia and the British Columbia Institute of Technology have received $7.7 million in funding from the Canada Foundation of Innovation to create the Prometheus Project — a research hub for materials science and engineering innovation and commercialization.

“Our goal with the Prometheus Project is to turn our world-class research capacity into jobs and growth for the people of British Columbia,” said Neil Branda, Canada Research Chair in Materials Science at Simon Fraser University and leader of the Prometheus Project. “We know that materials science is changing the way we create energy and fight disease. We think it can also help B.C.’s economy evolve.”

This project builds on a strong collective legacy of collaborating with industry. Researchers involved in the Prometheus Project have created 13 spin-off companies, filed 67 patents and have generated 243 new processes and products. [emphasis mine] Branda himself has founded a company called Switch Materials that seizes the power of advanced chemistry to create smarter and more efficient window coatings.

This funding will allow members of the research team to build their capacity in fabrication, device testing and advanced manufacturing, ensuring that they have the resources and expertise they need to compete globally.

There’s a bit more information about the Prometheus project in a Jan.15, 2013 backgrounder supplied by SFU,

Led by Neil Branda, a Canada Research Chair in Materials Science and SFU chemistry professor, The Prometheus Project is destined to become a research hub for materials science and engineering innovation, and commercialization globally.

It brings together 10 principal researchers, including Branda, co-founder of SFU’s 4D LABS (a materials research facility with capabilities at the nanoscale], and 20 other scientists at SFU, University of British Columbia, the University of Victoria and the British Columbia Institute of Technology. They will create new materials science and engineering (MS&E) technology innovations, which will trigger and support sustained economic growth by creating, transforming and making obsolete entire industries.

Working with internationally recognized industrial, government, hospital and academic collaborators, scientists at the Prometheus partners’ labs, including 4D LABS, a $40 million materials science research institute, will deliver innovations in three areas. The labs will:

  • Develop new solar-industry related materials and devices, including novel organic polymers, nanoparticles, and quantum dots, which will be integrated in low cost, high efficiency solar cell devices. The goal is to create a new generation of efficient solar cells that can compete in terms of cost with non-renewable technologies, surpassing older ones in terms of miniaturization and flexibility.
  • Develop miniaturized biosensors that can be used by individuals in clinical settings or at home to allow early detection of disease and treatment monitoring. They will be integrated into flexible electronic skins, allowing health conditions to be monitored in real-time.
  • Develop spintronics (magnetic devices) and quantum computing and information devices that will enable new approaches to significantly improve encrypted communication and security in financial transactions.

“This project will allow B.C.’s four most research intensive institutes to collaborate on fundamental materials research projects with a wide range of potential commercial applications,” notes Branda. “By engaging with a large community of industry, government and NGO partners, we will move this research out of the lab and into society to solve current and future challenges in important areas such as energy, health and communications.”

The Prometheus team already has a strong network of potential end users of resulting technologies. It is based on its members’ relationships with many of more than 25 companies in BC commercializing solar, biomedical and quantum computing devices.

Researchers and industries worldwide will be able to access Prometheus’s new capabilities on an open-access basis. [emphasis mine]

There are a few things I’d like to point out (a) 13 spin-off companies? There’s no mention as to whether they were successful, i.e., created jobs or managed a life beyond government funding. (b) Patents as an indicator for innovation? As I’ve noted many, many times that’s a very problematic argument to make. (c) New processes and products? Sounds good but there are no substantiating details.  (d) Given the emphasis on commercializing discoveries and business, can I assume that open-access to Prometheus’ capabilities means that anyone willing and able to pay can have access?

In other exciting SFU news which also affects TRIUMF, an additional $1M is being awarded by the Canada Foundation for Innovation to upgrade the ATLAS Tier-1 Data Analysis Centre. From the SFU backgrounder,

Led by Mike Vetterli, a physics professor at SFU and TRIUMF, this project involves collaborating with scientists internationally to upgrade a component of a global network of always-on computing centres. Collectively, they form the Worldwide Large Hadron Collider Computing Grid (WLCG).

The Canadian scientists collaborating with Vetterli on this project are at several research-intensive universities. They include Carleton University, McGill University, University of British Columbia, University of Alberta, University of Toronto, University of Victoria, Université de Montréal, and York University, as well as TRIUMF. It’s Canada’s national lab for particle and nuclear physics research.

The grid, which has 10 Tier-1 centres internationally, is essentially a gigantic storage and processing facility for data collected from the ATLAS  experiment. The new CFI funding will enable Vetterli and his research partners to purchase equipment to upgrade the Tier-1 centre at TRIUMF in Vancouver, where the equipment will remain.

ATLAS is a multi-purpose particle detector inside a massive atom-smashing collider housed at CERN, the world’s leading laboratory for particle physics in Geneva, Switzerland.

More than 3,000 scientists internationally, including Vetterli and many others at SFU, use ATLAS to conduct experiments aimed at furthering global understanding of how the universe was physically formed and operates.

The detector’s fame for being a window into nature’s true inner workings was redoubled last year. It helped scientists, including Vetterli and others at SFU, discover a particle that has properties consistent with the Higgs boson.

Peter Higgs, a Scottish physicist, and other scientists theorized in 1964 about the existence of the long-sought-after particle that is central to the mechanism that gives subatomic particles their mass.

Scientists now need to upgrade the WLCG to accommodate the massive volume of data they’re reviewing to confirm that the newly discovered particle is the Higgs boson. If it is, it will revolutionize the way we see mass in physics.

“This project will enable Canadian scientists to continue to play a leading role in ATLAS physics analysis projects such as the Higgs boson discovery,” says Vetterli. “Much more work and data are required to learn more about the Higgs-like particle and show that it is indeed the missing link to our understanding of the fundamental structure of matter.

There is one more Canada Foundation for Innovation grant to be announced here, it’s a $1.6M grant for research that will be performed at TRIUMF, according to the Jan. 13, 2013 news release from St. Mary’s University (Halifax, Nova Scotia),

Dr. Rituparna Kanungo’s newest research collaboration has some lofty goals: improve cancer research, stimulate the manufacturing of high-tech Canadian-made instrumentation and help explain the origin of the cosmos.

The Saint Mary’s nuclear physicist’s goal moved one step closer to reality today when the federal government announced $1.6 million in support for an advanced research facility that will allow her to recreate, purify, and condition rare isotopes that haven’t existed on the planet for millions of years.

The federal fiscal support from the Canada Foundation for Innovation together with additional provincial and private sector investment will allow the $4.5 million project to be operational in 2015.

“The facility will dramatically advance Canada’s capabilities for isolating, purifying, and studying short-lived isotopes that hold the key not only for understanding the rules that govern the basic ingredients of our everyday lives but also for crafting new therapies that could target and annihilate cancers cell-by-cell within the human body, “ said Dr Kanungo.

The CANadian Rare-isotope facility with Electron-Beam ion source (CANREB) project is led by Saint Mary’s University partnering with the University of Manitoba and Advanced Applied Physics Solutions, Inc. in collaboration with the University of British Columbia, the University of Guelph, Simon Fraser University, and TRIUMF. TRIUMF is Canada’s national laboratory for particle and nuclear physics. It is owned and operated as a joint venture by a consortium of Canadian universities that includes Saint Mary’s University.

…

As one of the nation’s top nuclear researchers (she was one of only two Canadians invited to speak at a Nobel Symposium last June about exotic isotopes), Dr. Kanungo has been conducting research at the TRIUMF facility for many years, carrying out analyses from her office at Saint Mary’s University together with teams of students. Her students also often spend semesters at the Vancouver facility.

As the project leader for the new initiative, she said TRIUMF is the ideal location because of its world leading isotope-production capabilities and its ability to produce clean, precise, controlled beams of selected exotic isotopes not readily available anywhere else in the world.

In recent studies in the U.S., some of these isotopes have been shown to have dramatic impact in treating types of cancer, by delivering radioactive payloads directly to the cancerous cells. Canada’s mastery of the technology to isolate, study, and control these isotopes will change the course of healthcare.

An integral part of the project is the creation of a new generation of high resolution spectrometer using precision magnets. Advanced Cyclotron Systems, Inc. a company in British Columbia, has been selected for the work with the hope that the expertise it develops during the venture will empower it to design and build precision-magnet technology products for cutting-edge projects all around the world.

Exciting stuff although it does seem odd that the federal government is spreading largesse when there’s no election in sight. In any case, bravo!

There’s one last piece of news, TRIUMF is welcoming a new member to its board, from its Jan. 14, 2013 news release,

Dr. Sylvain Lévesque, Vice-President of Corporate Strategy at Bombardier Inc., a world-leading manufacturer of innovative transportation solutions, has joined the Board of Management for TRIUMF, Canada’s national laboratory for particle and nuclear physics, for a three-year term.  Owned and operated by a consortium of 17 Canadian universities with core operating funds administered via a contribution agreement through National Research Council Canada, TRIUMF is guided by a Board that includes university vice-presidents of research, prestigious scientists, and leading members of Canada’s private sector.

Paul Young, Chair of TRIUMF’s Board and Vice President, Research at the University of Toronto, said, “We welcome the participation of Sylvain and his extensive experience at Bombardier.  TRIUMF is a national resource for basic research and yet we also fulfill a technological innovation mission for Canada.  Dr. Lévesque will be a valuable addition to the Board.”

Dr. Sylvain Lévesque earned his Ph.D. from MIT in Engineering and worked at McKinsey & Company before joining Bombardier in 1999.  He brings deep experience with large, technical organizations and a passion for science and engineering. [emphasis mine]  He said, “I am excited to work more closely with TRIUMF.  It has a track record of excellence and I am eager to provide guidance on where Canada’s industrial sector might draw greater strength from the laboratory.”

TRIUMF’s Board of Management reflects the unique status of TRIUMF, a laboratory operating for more than forty years as a joint venture from Canada’s leading research universities.  The consortium includes universities from Halifax to Victoria.

Is deep experience like wide experience or is it a whole new kind of experience helpful for ‘getting one’s groove on’? For anyone who’s curious, ‘getting one’s groove on’ involves dancing.

Squishy knees and tissue engineering at Johns Hopkins

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Researchers at Johns Hopkins University School of Medicine’s Translational Tissue Engineering Center (TTEC) have developed a material (a kind of hydrogel) which they use with a new technique they’ve developed for growing new tissue and cartilage in knees. From the Jan. 15, 2013 news release on EurekAlert,

Proof-of-concept clinical trial in 18 patients shows improved tissue growth

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a “hydrogel” scaffolding into the wound to support and nourish the healing process. The squishy hydrogel material was implanted in 15 patients during standard microfracture surgery, in which tiny holes are punched in a bone near the injured cartilage. The holes stimulate patients’ own specialized stem cells to emerge from bone marrow and grow new cartilage atop the bone.

…

“Our pilot study indicates that the new implant works as well in patients as it does in the lab, so we hope it will become a routine part of care and improve healing,” says Jennifer Elisseeff, Ph.D., Jules Stein Professor of Ophthalmology and director of the Johns Hopkins University School of Medicine’s Translational Tissue Engineering Center (TTEC). Damage to cartilage, the tough-yet-flexible material that gives shape to ears and noses and lines the surface of joints so they can move easily, can be caused by injury, disease or faulty genes. Microfracture is a standard of care for cartilage repair, but for holes in cartilage caused by injury, it often either fails to stimulate new cartilage growth or grows cartilage that is less hardy than the original tissue.

Here are more details from the Johns Hopkins Jan. 15, 2013 news release,

Tissue engineering researchers, including Elisseeff, theorized that the specialized stem cells needed a nourishing scaffold on which to grow, but demonstrating the clinical value of hydrogels has “taken a lot of time,” Elisseeff says. By experimenting with various materials, her group eventually developed a promising hydrogel, and then an adhesive that could bind it to the bone.

After testing the combination for several years in the lab and in goats, with promising results, she says, the group and their surgeon collaborators conducted their first clinical study, in which 15 patients with holes in the cartilage of their knees received a hydrogel and adhesive implant along with microfracture. For comparative purposes, another three patients were treated with microfracture alone. After six months, the researchers reported that the implants had caused no major problems, and MRIs showed that patients with implants had new cartilage filling an average 86 percent of the defect in their knees, while patients with only microfracture had an average of 64 percent of the tissue replaced. Patients with the implant also reported a greater decrease in knee pain in the six months following surgery, according to the investigators.

The trial continues, has enrolled more patients and is now being managed by a company called Biomet. The trial is part of efforts to win European regulatory approval for the device.

In the meantime, Elisseeff says her team has begun developing a next-generation implant, one in which the hydrogel and adhesive will be combined in a single material. In addition, they are working on technologies to lubricate joints and reduce inflammation.

The study has been published in the AAAS’s (American Association for the Advancement of Science) Science Translational Medicine journal,

Human Cartilage Repair with a Photoreactive Adhesive-Hydrogel Composite

Surgical options for cartilage resurfacing may be significantly improved by advances and application of biomaterials that direct tissue repair. A poly(ethylene glycol) diacrylate (PEGDA) hydrogel was designed to support cartilage matrix production, with easy surgical application. A model in vitro system demonstrated deposition of cartilage-specific extracellular matrix in the hydrogel

Sci Transl Med 9 January 2013:
Vol. 5 no. 167 pp. 167ra6DOI:10.1126/scitranslmed.3004838

This article is behind a paywall and for some reason the authors are listed only in the news release,

Jennifer Elisseeff, Blanka Sharma, Sara Fermanian, Matthew Gibson, Shimon Unterman, Daniel A. Herzka, Jeannine Coburn and Alexander Y. Hui of the Johns Hopkins School of Medicine; Brett Cascio of Lake Charles Memorial Hospital; Norman Marcus, a private practice orthopedic surgeon; and Garry E. Gold of Stanford University

Can you deflate your spike-studded balloon?

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Researchers at North Carolina State University have developed a means for embedding carbon nanofiber spikes (or needles)  into an elastic-like membrane to create a studded balloon that could potentially be used for drug delivery according to a Jan. 15, 2013 news item on ScienceDailyOnline,

The research community is interested in finding new ways to deliver precise doses of drugs to specific targets, such as regions of the brain. One idea is to create balloons embedded with nanoscale spikes that are coated with the relevant drug. Theoretically, the deflated balloon could be inserted into the target area and then inflated, allowing the spikes on the balloon’s surface to pierce the surrounding cell walls and deliver the drug. The balloon could then be deflated and withdrawn.

But to test this concept, researchers first needed to develop an elastic material that is embedded with these aligned, nanoscale needles. That’s where the NC State [North Carolina State University] research team came in.

“We have now developed a way of embedding carbon nanofibers in an elastic silicone membrane and ensuring that the nanofibers are both perpendicular to the membrane’s surface and sturdy enough to impale cells,” says Dr. Anatoli Melechko, an associate professor of materials science and engineering at NC State and co-author of a paper on the work.

For some reason this description brought to mind medieval weapons of war such as this  flail (the ball

Flail-Klassischer-Flegel (Deutsch: Ein mit einem Lederriemen verzierter klassischer Flegel mit kugelförmigem Kopf und Kette als Faustriemen) Credit: Tim Avatar Bartel [downloaded from: http://en.wikipedia.org/wiki/File:Klassischer-Flegel.jpg]

Flail-Klassischer-Flegel (Deutsch: Ein mit einem Lederriemen verzierter klassischer Flegel mit kugelförmigem Kopf und Kette als Faustriemen) Credit: Tim Avatar Bartel [downloaded from: http://en.wikipedia.org/wiki/File:Klassischer-Flegel.jpg]

not the stick. There’s much more about the flail and its use as a weapon in this Wikipedia essay.

As for this nanoscaled balloon studded with carbon nanofibers, the Jan. 15, 2013 North Carolina State University news release, which originated the news item, goes on to describe the technique,

The researchers first “grew” the nanofibers on an aluminum bed, or substrate. They then added a drop of liquid silicone polymer. The polymer, nanofibers and substrate were then spun, so that centrifugal force spread the liquid polymer in a thin layer between the nanofibers – allowing the nanofibers to stick out above the surface. The polymer was then “cured,” turning the liquid polymer into a solid, elastic membrane. Researchers then dissolved the aluminum substrate, leaving the membrane embedded with the carbon nanofibers “needles.”

“This technique is relatively easy and inexpensive,” says Melechko, “so we are hoping this development will facilitate new research on targeted drug-delivery methods.”

The paper, “Transfer of Vertically Aligned Carbon Nanofibers to Polydimethylsiloxane (PDMS) while Maintaining their Alignment and Impalefection Functionality,” is published online in the journal ACS Applied Materials & Interfaces. Lead authors on the paper are Ryan Pearce, a Ph.D. student at NC State, and Justin Railsback, a former NC State student now pursuing a Ph.D. at Northwestern University. Co-authors are Melechko; Dr. Joseph Tracy, an assistant professor of materials science and engineering at NC State; Bryan Anderson and Mehmet Sarac, Ph.D. students at NC State; and Timothy McKnight of Oak Ridge National Laboratory.

It’s very interesting but I wonder how they plan to deflate the balloon and what will happen to the carbon nanofiber needles and balloon membrane after their usage?

National Graphene Institute at the UK’s University of Manchester

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It will house the UK’s graphene research efforts according to the Jan. 14, 2013 news item Nanowerk,

This is the first glimpse of the new £61m research institute into wonder material graphene, which is to be built at The University of Manchester.

The stunning, glass-fronted National Graphene Institute (NGI) will be the UK’s home of research into the world’s thinnest, strongest and most conductive material, providing the opportunity for researchers and industry to work together on a huge variety of potential applications.

The University of Manchester Jan. 14, 2013 news release, which originated the news item, spells out some of the hopes and dreams along with descriptions of the building plans,

It is hoped the centre will initially create around 100 jobs, with the long-term expectation of many thousands more in the North West and more widely in the UK.

The 7,600 square metre building will house state-of-the-art facilities, including two ‘cleanrooms’ – one which will take up the whole of the lower ground floor – where scientists can carry out experiments and research without contamination.

The Institute will also feature a 1,500 square metre research lab for University of Manchester graphene scientists to collaborate with their colleagues from industry and other UK universities.

Funding for the NGI will come from £38m from the Government, as part of £50m allocated for graphene research, and the University has applied for £23m from the European Research and Development Fund (ERDF). The NGI will operate as a ‘hub and spoke’ model, working with other UK institutions involved in graphene research.

Some of the world’s leading companies are also expected to sign up to work at the NGI, where they will be offered the chance to work on cutting edge projects, across various sectors, with Nobel Laureates and other leading members of the graphene team.

Graphene, isolated for the first time at The University of Manchester by Professor Andre Geim and Professor Kostya Novoselov in 2004, has the potential to revolutionise a huge number of diverse applications; from smartphones and ultrafast broadband to drug delivery and computer chips.

…
Professor Colin Bailey, Vice-President and Dean of the Faculty of Engineering and Physical Sciences, added: “The National Graphene Institute will be the world’s leading centre of graphene research, combining the expertise of University of Manchester academics with their counterparts at other UK universities and with leading global commercial organisations.

“The potential for its impact on the city and the North West is huge, and will be one of the most exciting centres of cutting edge research in the UK.”

Work is set to start on the five-story NGI, which will have its entrance on Booth Street East, in March, and is expected to be completed in early 2015.

UK National Graphene Institute (NGI) Illustration courtesy of the University of Manchester, UK

UK National Graphene Institute (NGI) Illustration courtesy of the University of Manchester, UK

The University of Manchester is one of the institutions that forms the Graphene Flagship consortium which is currently competing for one of two European Union prizes of 1 Billion Euros for research to be awarded later this year.