Monthly Archives: March 2018

Bulletproof graphene

Leave a reply

A December 18, 2017 news item on Nanowerk announces research that demonstrates graphene can be harder than diamonds (Note: A link has been removed),

Imagine a material as flexible and lightweight as foil that becomes stiff and hard enough to stop a bullet on impact. In a newly published paper in Nature Nanotechnology (“Ultrahard carbon film from epitaxial two-layer graphene”), researchers across The City University of New York (CUNY) describe a process for creating diamene: flexible, layered sheets of graphene that temporarily become harder than diamond and impenetrable upon impact.

Scientists at the Advanced Science Research Center (ASRC) at the Graduate Center, CUNY, worked to theorize and test how two layers of graphene — each one-atom thick — could be made to transform into a diamond-like material upon impact at room temperature. The team also found the moment of conversion resulted in a sudden reduction of electric current, suggesting diamene could have interesting electronic and spintronic properties. The new findings will likely have applications in developing wear-resistant protective coatings and ultra-light bullet-proof films.

A December 18, 2017 CUNY news release, which originated the news item, provides a little more detail,

“This is the thinnest film with the stiffness and hardness of diamond ever created,” said Elisa Riedo, professor of physics at the ASRC and the project’s lead researcher. “Previously, when we tested graphite or a single atomic layer of graphene, we would apply pressure and feel a very soft film. But when the graphite film was exactly two-layers thick, all of a sudden we realized that the material under pressure was becoming extremely hard and as stiff, or stiffer, than bulk diamond.”

Angelo Bongiorno, associate professor of chemistry at CUNY College of Staten Island and part of the research team, developed the theory for creating diamene. He and his colleagues used atomistic computer simulations to model potential outcomes when pressurizing two honeycomb layers of graphene aligned in different configurations. Riedo and other team members then used an atomic force microscope to apply localized pressure to two-layer graphene on silicon carbide substrates and found perfect agreement with the calculations. Experiments and theory both show that this graphite-diamond transition does not occur for more than two layers or for a single graphene layer.

“Graphite and diamonds are both made entirely of carbon, but the atoms are arranged differently in each material, giving them distinct properties such as hardness, flexibility and electrical conduction,” Bongiorno said. “Our new technique allows us to manipulate graphite so that it can take on the beneficial properties of a diamond under specific conditions.”

The research team’s successful work opens up possibilities for investigating graphite-to-diamond phase transition in two-dimensional materials, according to the paper. Future research could explore methods for stabilizing the transition and allow for further applications for the resulting materials.

There’s an artist’s representation of a bullet’s impact on graphene,

By applying pressure at the nanoscale with an indenter to two layers of graphene, each one-atom thick, CUNY researchers transformed the honeycombed graphene into a diamond-like material at room temperature. Photo credit: Ella Maru Studio Courtesy: CUNY

Here’s a link to and a citation for the paper,

Ultrahard carbon film from epitaxial two-layer graphene by Yang Gao, Tengfei Cao, Filippo Cellini, Claire Berger, Walter A. de Heer, Erio Tosatti, Elisa Riedo, & Angelo Bongiorno. Nature Nanotechnology (2017) doi:10.1038/s41565-017-0023-9 Published online: 18 December 2017

This paper is behind a paywall.

Art influences science

Leave a reply

It’s not often you see research that combines biologically inspired engineering and a molecular biophysicist with a professional animator who worked at Peter Jackson’s (Lord of the Rings film trilogy, etc.) Park Road Post film studio. An Oct. 18, 2017 news item on ScienceDaily describes the project,

Like many other scientists, Don Ingber, M.D., Ph.D., the Founding Director of the Wyss Institute, is concerned that non-scientists have become skeptical and even fearful of his field at a time when technology can offer solutions to many of the world’s greatest problems. “I feel that there’s a huge disconnect between science and the public because it’s depicted as rote memorization in schools, when by definition, if you can memorize it, it’s not science,” says Ingber, who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children’s Hospital, and Professor of Bioengineering at the Harvard Paulson School of Engineering and Applied Sciences (SEAS). “Science is the pursuit of the unknown. We have a responsibility to reach out to the public and convey that excitement of exploration and discovery, and fortunately, the film industry is already great at doing that.”

An October 18, 2017 Wyss Institute at Harvard University news release (also on EurekAlert) by Lindsay Brownell, which originated the news item, details the work,

To see if entertainment could offer a solution to this challenge, Ingber teamed up with Charles Reilly, Ph.D., a molecular biophysicist, professional animator, and Staff Scientist at the Wyss Institute who previously worked at movie director Peter Jackson’s Park Road Post film studio, to create a film that would capture viewers’ imaginations by telling the story of a biological process that was accurate down to the atomic level. “Don and I quickly found that we have a lot of things in common, especially that we’re both systems thinkers,” says Reilly. “Applying an artistic process to science frees you from the typically reductionist approach of analyzing one particular hypothesis and teaches you a different way of observing things. As a result, we not only created an entertaining tool for public outreach, we conducted robust theoretical biology research that led to new scientific insight into molecular-scale processes.” The research is now published in ACS Nano and the film can be found here.

Wyss researchers created a model of an axoneme that displays how different segments of the microtubules bend and flex relative to each other to create movement. Credit: Wyss Institute at Harvard University

Any good movie needs characters and drama, and a “hook” to get the audience invested in watching. The scientists decided to make a parody of a trailer for a Star Wars® movie, but instead of showing starship cruisers hurtling through space towards the Death Star, they chose a biological process with its own built-in narrative: the fertilization of an egg by a sperm, in which millions of sperm race to be the one that succeeds and creates the next generation of life. The patterns and mechanics of sperm swimming have been studied and described in scientific literature, but visually showing the accurate movement of a sperm tail required tackling one of the toughest challenges facing science today: how to create a multi-scale biological model that maintains accuracy at different sizes, from cells all the way down to atoms. That would be like starting with the Empire State Building and then zooming in close enough to see every individual screw, nut and bolt that holds it together, as well as how individual water molecules flow inside its pipes, while maintaining crystal-clear resolution – not an easy task.

“It turns out that creating an accurate biological model and creating a believable computer-generated depiction of life in film are very similar, in that you’re constantly troubleshooting and modifying your virtual object until it fits the way things actually look and move,” says Reilly. “However, for biology, the simulations also have to align with recorded scientific data and theoretical models that have previously been experimentally validated.” The scientists created a design-based animation pipeline that integrates physics-based film animation software with molecular dynamics simulation software to create a model of how a sperm tail moves based on scientific data, with the criterion that the model had to work across all size scales. “This is really a design thinking approach, where you have to be willing to throw out your model if it doesn’t work correctly when you integrate it with data from another scale,” Reilly says. “A lot of scientific investigations use a reductionist approach, focusing on one molecule or one biological system with higher and higher resolution without placing it in context, which makes it difficult to converge on a picture of the larger whole.”

This video shows dynein’s two different shapes as determined from scientific observations, and how the Wyss researchers’ molecular model of dynein’s movement fits those conformations. Credit: Wyss Institute at Harvard University

The core of a sperm’s whip-like tail is the axoneme, a long tube consisting of nine pairs of microtubules arranged in a column around a central pair, all of which extend the entire length of the tail. The axoneme’s rhythmic bending and stretching is the source of the tail’s movement, and the scientists knew they needed to realistically depict that process in order to show the film’s viewers how a sperm moves. Rather than construct a model in a linear fashion by “zooming in” or “zooming out” to add more information to a single starting structure, they built the model at different scales simultaneously, repeatedly checking it against scientific data to ensure it was accurate and modifying it until the pieces fit together.

The axoneme’s movement is accomplished via rows of motor proteins called dyneins that are attached along the microtubules and exert force on them so the microtubules “slide” past each other, which then causes the entire axoneme and sperm tail to bend and move. The dynein protein has a long “arm” portion that grabs onto the neighboring microtubule and, when the protein changes from one shape to another, pulls the microtubule along with it. Dynein switches between these different conformations as a result of the conversion of a molecule of ATP to ADP at a specific binding site on the protein, which releases energy as a chemical bond is broken. To model this molecular motor, the scientists created a molecular dynamics simulation of a dynein protein and applied energy at the ATP binding site to approximate the transfer of energy from ATP. They found that this caused atoms in the entire protein to move in random directions when they performed their simulation of dynein floating in solution, as most conventional scientific simulations do. However, when they then “fixed” a specific hinge region of the dynein molecule that is known to connect dynein to its microtubule, they discovered that the dynein spontaneously moved in its characteristic direction when force was applied at the ATP binding site, matching the way it moves in nature.

This video shows rows of dynein proteins along the microtubules of an axoneme moving in sync to cause the axoneme’s motion, like rowers pulling synchronously in a boat. Credit: Wyss Institute at Harvard University

“Not only is our physics-based simulation and animation system as good as other data-based modeling systems, it led to the new scientific insight that the limited motion of the dynein hinge focuses the energy released by ATP hydrolysis, which causes dynein’s shape change and drives microtubule sliding and axoneme motion,” says Ingber. “Additionally, while previous studies of dynein have revealed the molecule’s two different static conformations, our animation visually depicts one plausible way that the protein can transition between those shapes at atomic resolution, which is something that other simulations can’t do. The animation approach also allows us to visualize how rows of dyneins work in unison, like rowers pulling together in a boat, which is difficult using conventional scientific simulation approaches.”

Using this biologically accurate model of how dynein moves the microtubules within the axoneme, Ingber and Reilly created a short film called “The Beginning,” which draws parallels between sperm swimming toward an egg and spaceships flying toward a planet in space, giving an artistic bent to a scientific topic. The film depicts several sperm attempting to fertilize the egg, “zooms in” on one sperm’s tail to show how the dynein proteins move in sync to cause the tail to bend and flex, and ends with the sperm’s successful journey into the egg and the initiation of cell division that will ultimately create a new organism. The scientists submitted the film along with the paper to several academic journals, and it took a long time before they found an open-minded editor who recognized that the paper and film together were a powerful demonstration of how starting with an artistic goal can end up generating new scientific discoveries along with a tool for public outreach.

*Due to distortion images deleted March 9, 2018.*

“Both science and art are about observation, interpretation, and communication. Our goal is that presenting science to the public in an entertaining, system-based way, rather than bogging them down with a series of scattered facts, will help more people understand it and feel that they can contribute to the scientific conversation. The more people engage with science, the more likely humanity is to solve the world’s big problems,” says Reilly. “I also hope that this paper and video encourage more scientists to take an artistic approach when they start a new project, not necessarily to create a narrative-based story, but to explore their idea the way an artist explores a canvas, because that makes the mind open to a different form of serendipity that can lead to unexpected results.”

“The Wyss Institute is driven by biological design. In this project, we used design tools and approaches borrowed from the art world to solve problems related to motion, form, and complexity to create something entertaining, which ultimately led to new scientific insights and, hopefully, new ways to excite the public about science,” says Ingber. “We’ve demonstrated that art and science can benefit each other in a truly reciprocal way, and we hope that this project spurs future collaborations with the entertainment industry so that both art and science can get even closer to depicting reality in ways that anyone can appreciate and enjoy.”

*Due to distortion images deleted on March 9, 2018.*

The film,

Here’s a link to and a citation for the paper,

Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale by Charles Reilly and Donald E. Ingber. ACS Nano, Article ASAP DOI: 10.1021/acsnano.7b05266 Publication Date (Web): October 18, 2017

Copyright © 2017 American Chemical Society

This paper appears to be open access.

German scientists battle tough mucus

Leave a reply

A December 15, 2017 news item on ScienceDaily highlights cystic fibrosis research being done in Germany,

Around one in 3,300 children in Germany is born with Mucoviscidosis [cystic fibrosis; CF]. A characteristic of this illness is that one channel albumen on the cell surface is disturbed by mutations. Thus, the amount of water of different secretions in the body is reduced which creates a tough mucus. As a consequence, inner organs malfunction. Moreover, the mucus blocks the airways. Thus, the self regulatory function of the lung is disturbed, the mucus is colonized by bacteria and chronic infections follow. The lung is so significantly damaged that patients often die or need to have a lung transplant. The average life expectancy of a patient today is around 40 years. This is due to medical progress. Permanent treatment with inhaled antibiotics play a considerable part in this. The treatment can’t avoid the colonization by bacteria completely but it can keep it in check for a longer period of time. However, the bacteria defend themselves with a development of resistance and with the growth of so-called biofilms underneath the layer of mucus, which mostly block off the bacteria in the lower rows like a protective shield.

A complex way to the Pathogens

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing a much more efficient method to treat the airway infections which are often lethal. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination….

A December 15, 2017 Friedrich Schiller University Jena press release (also on EurekAlert), which originated the news item, expands on the theme,

“Typically, the drugs are applied by inhalation in the body. Then they make a complicated way through the body to the pathogens and many of them don’t make it to their destination,” states Prof. Dr Dagmar Fischer of the chair for Pharmaceutical Technology at the University of Jena, who supervised the project together with her colleague Prof. Dr Mathias Pletz, a pulmonologist and infectious diseases physician, from the Center for Infectious Diseases and Infection Control at the Jena University Hospital. The project was supported by the Deutsche Forschungsgemeinschaft. First of all, the active particles need to have a certain size to be able to reach the deeper airways and not to bounce off somewhere else before. Ultimately, they have to penetrate the thick layer of mucus on the airways as well as the lower layers of the bacteria biofilm.

Nanoparticles travel more efficiently

To overcome the strong defense, the researchers encapsulated the active agents, like the antibiotic Tobramycin, in a polyester polymer. Thus, they created a nanoparticle which they then tested in the laboratory where they beforehand had simulated the present lung situation, in a static as well as in a dynamic state, i. e. with simulated flow movements. Therefore Pletz’s research group had developed new test systems, which are able to mimick the situation of the chronically infected CF-lung. The scientists discovered that their nanoparticle travels more easily through the sponge-like net of the mucus layer and is finally able to kill off the pathogens without any problems. Moreover, an additionally applied coating of polyethylenglycol makes it nearly invisible for the immune system. “All materials of a nanocarrier are biocompatible, biodegradable, nontoxic and therefore not dangerous for humans,” the researcher informs.

However, the Jena scientists don’t know yet exactly why their nanoparticle fights the bacteria so much more efficiently. But they want to finally get clarification in the year ahead. “We have two assumptions: Either the much more efficient transport method advances significantly larger amounts of active ingredients to the center of infection, or the nanoparticle circumvents a defense mechanism, which the bacterium has developed against the antibiotic,” the Jena Pharmacist Fischer explains. “This would mean, that we succeeded in giving back its impact to an antibiotic, which had already lost it through a development of resistance of the bacteria.”

“More specifically, we assume that bacteria from the lower layers of the biofilm transform into dormant persisters and hardly absorb any substances from outside. In this stadium, they are tolerant to most antibiotics, which only kill off self-dividing bacteria. The nanoparticles transport the antibiotics more or less against their will to the inner part of the cell, where they can unfold their impact,” Mathias Pletz adds.

Additionally, the Jena research team had to prepare the nanoparticles for the inhalation. Because at 200 nanometers the particle is too small to get into the deeper airways. “The breathing system filters out particles that are too big as well as those which are too small,” Dagmar Fischer explains. “So, we are left with a preferred window of between one and five micrometers.” The Jena researchers also have promising ideas for resolving this problem.

Coating of Nanoparticles enhances the impact of Antibiotics against Biofilms

The scientists from Jena are at this point already convinced to have found a very promising method to fight respiratory infections of patients with mucoviscidosis. Thus they may be able to contribute to a higher life expectancy of those affected. “We were able to show that the nanoparticle coating improves the impact of the antibiotics against biofilm by a factor of 1,000,” the pulmonologist and infectious diseases physician is happy to say.

It’s exciting news and I wish the researchers great success. Perhaps, one day, they will publish a paper about their work.

What is happening with Alberta’s (Canada) Ingenuity Lab?

Leave a reply

Alberta’s Ingenuity Lab (first mentioned here in a November 19, 2013 posting) seems to have been launched sometime in 2012 (or maybe 2013). It;s a province of Alberta initiative and at the time of I first heard of it I questioned the necessity for another nanotechnology institution in Alberta (or anywhere else in Canada for that matter).

Amuse bouche: a roundup of the Canadian nanotechnology scene

Since 2012/3 a great many things have changed. The National Institute of Nanotechnology (NINT) seems to have become almost completely dormant; the same can be said for Canada’s NanoPortal and nanoAlberta.

Adding to this brief roundup of the nanotechnology scene in Canada, the province of Alberta lists their various facilities on their Nanotechnology and microsystems webpage. As that page was last updated on 2012 you may find the information no longer viable.

A quick search for NanoQuébec yielded Prima Québec; Pôle recherche innovation matériaux avancés (that’s research for innovation and advanced materials; I think). Finally, there is still a Nano Ontario.

Should anyone know of a Canadian ‘nano’ institution that should be included, please do let me know in the ‘comments’.

Ingenuity Lab: Basics

The University of Alberta’s Faculty of Engineering’s Engineering Research webpage (copyright 2002-2018) describes the Ingenuity Lab this way,

ingenuity Lab (the Nanotechnology Accelerator) is a large scale ($100M), 10-year, multidisciplinary research and development initiative co-located at the Faculty of Engineering,  the University of Alberta and the National Institute for Nanotechnology. Led by chemical engineering professor and Canada Research Chair holder Carlo Montemagno, iNgenuity is focused on groundbreaking bionanotechnology advances and innovative business practices that will enable Alberta to become a world-leading centre for nanotechnology innovation. (www.ingenuitylab.ca)

That’s a very large enterprise by Canadian standards.

After a great deal of initial promotion for both the lab and its director, Dr. Carlo Montemagno, the lab settled into a pattern of making bold announcements, many of which I covered here,

The blog search engine here privileges titles containing the search term (in this case, Ingenuity Lab) first and then restarts, in date order, all of the other ‘nontitle’ mentions. (I stopped with the titles.)

Last year (2017), there was a major change at the Ingenuity Lab, the director, Dr. Carlo Montemagno, moved to Illinois to become the Chancellor for Southern Illinois University (SIU). Unfortunately, I did not receive any response from Dr. Montemagno to the interview questions I sent him, twice, via email. I also emailed, once, SIU’s chief marketing and communications, Rae Goldsmith. For the curious, here are the questions,

(1) What differences did you experience as a researcher between the Canadian approach to nanotechnology (the National Institute of Nanotechnology is one of the Canada National Research Council’s institute’s) and the US approach (National Nanotechnology Initiative, a central funding hub and research focus for the US government)?

(2) Will your experience in Canada affect how you approach your work at SIU? Assuming, there is some influence, how will that experience affect your work at SIU?

(3) What are you most proud of achieving while leading Alberta’s Ingenuity Lab?

(4) Could you reflect on the trends you see with regard to nanotechnology not just in Canada and/or the US but internationally too?

(5) Is there anything else you’d like to add?

My questions were pretty much puffballs. In the meantime, it seems Dr. Montemagno attracted some serious journalistic interest, from a February 21, 2018 article by Dawn Rhodes for the Chicago Tribune,

When Chancellor Carlo Montemagno took the helm at Southern Illinois University Carbondale in July [2017], he set to work on a plan to dismantle and rebuild academics at the struggling campus, which has hemorrhaged enrollment over the past several years. His idea was a bold one, rarely if ever attempted at a large public university: eliminate academic departments.

The plan drew ire as well as praise, opening some bitter fissures among faculty, students and staff. That discord seems to have grown in recent weeks, particularly as the chancellor has become embroiled in controversies that have intensified scrutiny of his leadership.

In January [2018], SIU student paper The Daily Egyptian revealed the university hired Montemagno’s daughter and son-in-law shortly after he assumed the chancellor post. The investigation showed that the couple’s work history traces the same path as Montemagno’s, with the pair having held jobs at the same institutions he worked at for the past decade.

There have also been complaints that Montemagno is too directly influencing other hiring at the university — which he denies.

Both issues are the subjects of separate ethics investigations, SIU system President Randy Dunn said.

Then on Thursday [February 15, 2018?], the chancellor said he used part of his relocation allotment from the university to help cover the costs of moving his daughter’s family to southern Illinois, as well, adding up to $16,076.45. Montemagno said “there was a misunderstanding about what could be covered in the move” so he picked up the tab for part of the added costs and reimbursed SIU for the remaining expense of moving his daughter’s household.

The revelation that the new chancellor’s family members received jobs at Southern Illinois, which cut dozens of positions just weeks before his arrival and in the midst of the two-year state budget impasse, irked many at the university. It also drew sharp retorts from a member of the Illinois Board of Higher Education.

In an interview Monday [February 19, 2018?], Montemagno said he recognized the optics of using part of his moving allowance for his daughter’s benefit and decided to pay back the university. But he said he never hid the fact that his family members were hired by SIU and he shrugged off criticism he has received in recent weeks. Although it caught some by surprise, SIU leaders had, in fact, approved the family hires as part of the chancellor’s hiring negotiations.

…

Rhodes’ article provides fascinating insight into the political struggles currently taking place at SIU. I encourage you to read the piece in its entirety if you have the time.

Ingenuity Lab: We are family

The appearance of Melissa Germain (Montemagno’s daughter) and her husband, Jeffrey Germain (Montemagno’s son-in-law), in the article was a bit of a surprise. Both were involved with the Ingenuity Lab. (I contacted Melissa Germain years ago to get on the lab’s media list to receive all their news releases. She agreed to put me on the list but I never received anything from them. Whether that was by accident or by design, I’ll never know. Jeff Germain was, for a time, the Ingenuity Lab’s interim director.)

Logically, this means that the University of Alberta hired not only Dr. Montemagno but also his daughter and son-in-law. As Rhodes’ article notes, it’s not unusual for faculty members to insist their spouses also be given jobs. The surprise here is that Montemagno’s daughter and her spouse were part of the deal, informal (SIU?) or otherwise (Alberta?).

In trying to find more information about the Ingenuity Lab’s budgets and financials (unsuccessful), I stumbled across the glassdoor.ca site (accessed March 5, 2018), which features some comments about the working environment at Alberta’s Ingenuity lab,

11 Jul, 2017

Helpful (1)

“Family Run Lab with Public Funding at the University of Alberta”
Current Employee – Anonymous Employee in Edmonton, AB
Doesn’t Recommend
Negative Outlook

I have been working at Ingenuity Lab full-time (More than a year)

Pros

-You will learn how to handle uncomfortable environment very well.
-There are some good researchers and staffs in the group.

Cons

– It is a public funded lab that controls by family members. This is not the issue for a private company, but it makes it really unacceptable for a public funded research group.
– The family members without required credentials can override any decision easily.
– The management team (the family members) spend lots of public funding for publicity
-Some of the group members bend easily with wind to stay … Show More

Advice to Management

-Presenting FALSE FACTS has expiry date! It is important to leave good name behind.
-Bringing family members without any credentials on board is not being wise.
– Just investing on gaining publicity is not enough. Nowadays, having output has the final say.

Share on Facebook
Share on Twitter
Share via Email
Copy Link

Other Employee Reviews for Ingenuity Lab

21 Mar, 2017

Helpful (3)
Ingenuity Lab Logo
“A family run business”

Former Employee – Anonymous in Edmonton, AB
Doesn’t Recommend
Negative Outlook

I worked at Ingenuity Lab full-time (More than a year)

Pros

Well funded lab with all the facilities located in the National Institute of Nanotechnology. The labs are at a great location and easy access to Tim Hortons.

Cons

All the administrative posts are filled with family members. No good communication between researchers and the director is surrounded by his trust worthy group of highly qualified politicians. The projects are all hypothetical and there is a lack of passion for hardcore fundamental research. They run as in commercial companies and does not belong in the NINT. They should relocate in the industrial areas of South Edmonton.

Advice to Management

Start publishing papers in peer reviewed journals rather than cheap publicity in local and national newspapers.

Share on Facebook
Share on Twitter
Share via Email
Copy Link

8 Feb, 2016

Helpful (2)
Ingenuity Lab Logo
“Clouded vision of ingenuity”
Former Employee – Anonymous Employee

I worked at Ingenuity Lab full-time (Less than a year)

Pros

Plenty of funding, this place will be in business for at least the next three years. Most of the people are a pleasure to be around.

Cons

There is noticeable friction between different team leads. Lack of information between groups has led to a few costly mistakes. It is run much more like a company than research group, results that can make money or be patent-able are the only goals.

Advice to Management

Ditch the yes-men family members that you have installed, and hire industrial trained scientists if you want the results you are looking for.

It’s hard to know if there is one disgruntled person waging a campaign or if there are three very unhappy people from a lab team of about 100 scientists. But the complaints are made several months apart, which suggests three people and generally where there’s one complain there are more, unvoiced complaints. Interestingly, all three complaints focus on the Ingenuity Lab as a ‘family-run’ enterprise. It seems that Montemagno, like a certain US president, prefers to work with his family.

According to this article in The New Economy, Montemagno came to Alberta because it offered an opportunity to conduct research in a progressive fashion,,

In 2012, Dr Montemagno was lured back to the world of research when the opportunity to lead a large-scale nanotechnology accelerator initiative in Alberta materialised. His background traversing agricultural and bioengineering, petroleum engineering, and nanotechnology made him an ideal choice to lead the exciting new programme. The opportunity was significant and he viewed Alberta as a land of opportunity with an entrepreneurial spirit; he decided to make the move to Canada. The vision of advancing technologies to solve grand challenges recaptured his imagination. The initiative is now branded as Ingenuity Lab. [emphases mine]

Located within the University of Alberta, Canada, Ingenuity Lab is an assembly of multi-disciplinary experts who work closely to develop technological advancements in ways that are not otherwise possible. Not only is Ingenuity Lab different to other initiatives in the way it operates its goal-orientated and holistic approach, but also in the progressive way it conducts research. In this model, limitations on creativity that surround the traditional university faculty model (which rewards individual success and internal competition) are overcome.[emphases mine]

Three (at least) employees seem to suggest otherwise. Still, there are situations where trusted colleagues, familial or not, migrate together from one employer to another. For example, Nigel Lockyer was the Director for TRIUMF (Canada’s particle accelerator centre; formerly, Canada’s National Laboratory for Particle and Nuclear Physics). He brought on board with him, Timothy Meyer someone with whom (I believe) he had a previous working/professional relationship. Lockyer is now the Director of the Fermilab (University of Chicago, Illinois, US) and guess who also works at the Fermilab? Lockyer and Meyer were quite successful at TRIUMF and they appear to be revitalizing the Fermi Lab, which until their tenure seemed moribund. (See: University of Chicago Sept. 27, 2017 news release: Nigel Lockyer appointed to second term as director of Fermilab; and Timothy Meyer’s profile page on the Fermilab website to confirm the biographical details for yourself.)

These days, the Ingenuity Lab (accessed March 5, 2017) lists Murray Gray, PhD, as their interim director. He is a professor emeritus from the University of Alberta. There is still an Ingenuity Lab website, Facebook account, and Twitter account. The Twitter account has been inactive since August 2017, their website is curiously empty, while the Facebook account boasts a relatively recent posting of a research paper.

Final thoughts

With all the money for science funding flying around, it seems like it might be time to start assessing the ROI (return on investment) for these projects and, perhaps, giving a closer eye to how it’s spent (oversight) in the first place. In Canada.

Other than an occasional provincial or federal audit that might or might not occur, is anyone providing consistent oversight for these multimillion dollar science investments? For example, the Canadian federal government recently announced $950M investment in five superclusters (see Feb. 15, 2018 Innovation, Science and Economic Development Canada news release). One of the superclusters has to do with supply chains and AI (artificial intelligence. Here’s what Paul Wells in a Feb. 15, 2018 article for Maclean’s observed,

The AI supply-chain group from, essentially, Montreal (wait! I guess I’m just guessing about that) is comically gnomic. I could find no name of any actual person or company anywhere on the website. Only a series of Zen riddles. “Over 120 industrial and enabling institutions, from very large firms to start-ups, have joined forces in this journey,” the website says helpfully, “and we have strong momentum.”

You can see it for yourself here. Who will be providing oversight? At what intervals? And, how?

In searching for further information about funding and budgets, I found this (in addition to the feedback from disgruntled Ingenuity Lab employees), Dr. Carlo Montemagno received $556,295.06 in compensation and $40,215.81 for ‘other’ in 2016 and $538,345.35 in compensation and $37,815.98 for ‘other’ in 2015 (accessed March 5, 2018).

The information about Dr. Montemagno’s salary and benefits can be found on the University of Alberta’s Human Resource Services public Sector Compensation Disclosure page. Presumably, the 2017 figures have not yet been released, as well, Montegmagno’s 2017 salary .may not be disclosed for the same reason neither Melissa Germain’s nor Jeffrey Germain’s salaries are disclosed,

The Alberta government’s Public Sector Compensation Transparency Act (2015) requires that the University of Alberta disclose the name, position, compensation, non-monetary benefits and severance for all employees whose total compensation plus severance exceeds an annual threshold [emphasis mine]. Remuneration paid to members of the Board of Governors will also be disclosed. Disclosure must be published annually on or before June 30th for compensation paid in the previous calendar year. Employees who terminated between January 1 and June 30 that received pay in lieu of notice, pay during a period of notice and/or severance pay and the total of those amounts exceeds the threshold will be included on the disclosure list each December. The disclosure list will identify the name and the amount of severance. Any other compensation will be reported on the next June’s disclosure.

The Public Sector Compensation Transparency Act applies to more than 150 agencies, boards, and commissions, to independent offices of the Alberta Legislature, and to employees of Convenant Health.

For questions or concerns, please contact Wayne Patterson, Executive Director, Human Resource Services.

There may have been a good reason for Montemagno’s compensation of over 1/2 million dollars per year, for 2015 and 2016 at least. Researchers are expected to bring in money through research grants. I found one funding announcement for $1.7M from Natural Resources* Canada on the Ingenuity Lab’s news release page (accessed March 5, 2018).

Oddly, Dr. Montemagno was appointed chancellor at SIU on July 13, 2017 and his start date was August 15, 2017 (July 13, 2017 SIU news release). That’s unusually fast for an academic institution for a position at that level. Not to mention Montemagno’s position in Alberta.

SIU is not the only place to inspire Montemagno to dream (eliminate academic departments from their university as per Rhodes’ article). He dreamt big for Alberta too. From an Oct. 30,2015 article by Gary Lamphier for the Edmonton Journal,

…

Faced with so many serious challenges, it’s no surprise Alberta’s oilpatch and its once-envied economy are sputtering, prompting gleeful outbreaks of schadenfreude from Vancouver to Toronto.

But what if Alberta could upend the basic economic paradigm [emphasis mine] in which it operates? Suppose Alberta could curb its carbon emissions, thus shedding its nasty environmental reputation and giving it the social licence needed to build new oil pipelines, while diversifying the economy at the same time?

Sound impossible? Don’t be so sure. That’s Carlo Montemagno’s dream, and the world-renowned director of Alberta’s Ingenuity Lab, who heads a team of about 100 scientists, has a bold plan to do it. It’s called the carbon transformation project, and he hopes to pull it off by the end of this decade. [emphases mine]

If it works, the scheme would capture the carbon dioxide (CO2) emitted at any one of dozens of Alberta industrial sites, from power plants to petrochemical facilities, without requiring any massive retrofits or the kind of multibillion-dollar investments associated with carbon sequestration.

Through a process employing artificial light, water and electricity, it would harness industrial CO2 emissions to create more than 70 commercially valuable carbon-containing chemicals, Montemagno says. Such chemicals could form the essential building blocks for dozens of consumer and industrial products, ranging from auto antifreeze and polyester fibres to food additives.

The plan is brilliant in its simplicity. Montemagno’s team aims to turn a bad thing — CO2 — into a good thing, one that creates value, wealth, and new jobs. And he hopes to do it without trashing Alberta’s existing oil-fired economy.

Instead, his concept involves simply tacking one more process onto the province’s industrial sites, thus creating valuable new feedstock for existing or new industries.

“If it all works, it means you can produce products you need to satisfy local economic needs, create more value from emissions, generate more revenue and more products,” says Montemagno, who has science degrees from Cornell University, Penn State, and a PhD in civil engineering and geological sciences from University of Notre Dame.

“The big argument today is, you burn fossil fuels and release CO2 into the atmosphere, and end up causing global warming,” he says.

“But the problem isn’t that you’re burning fossil fuels. The problem is you’re releasing CO2 into the atmosphere. So is there an opportunity to not release CO2 and instead capture and use it in other products? It’s really about stating the problem in the appropriate language.”

With funding from Alberta’s Climate Change and Emissions Management Corp., Ingenuity Lab is hard at work developing a $1.3-million demonstration project to prove the concept. Montemagno hopes to have an industrial-scale pilot project running in three to four years. [emphasis mine]

…

Montemagno certainly had an exciting plan. And, 2018 would be around the time someone might expect to see the “industrial-scale pilot project for carbon transformation” mentioned (2015 + three to four years) in Lamphier’s article. Where is it? When is it starting?

And now, Montemagno has some exciting plans for SIU?

 

With regard to hiring family members, the Chicago Sun-Time Editorial Board (Feb. 5, 2018 editorial) does not approve,

Here’s a pro tip for you chancellors at hard-up public universities who are thinking about hiring your own daughters:

Don’t do it.

Don’t hire your sons-in-law, either.

EDITORIAL

It looks bad, and nobody afterward will feel quite so confident that you are serious about getting your university’s finances in order and protecting important academic programs.

They might look at you, fairly or not, like you’re an old-time Chicago ward boss.

Carlo Montemagno was hired last year as chancellor at Southern Illinois University Carbondale. He makes $340,000 a year.

That’s a lot of money, but top university talent doesn’t come cheap, not even at a state university that has been forced to cut millions of dollars from its budget in recent years and has considered cutting seven degree programs.

Then, on Sept. 1, 2017, three months after Montemagno came on board, his daughter, Melissa Germain, was hired as assistant director of university communications, with an annual salary of $52,000. One month later, his son-in-law, Jeffrey Germain, was hired as “extra help” in the office of the vice chancellor for research, at $45 an hour.

Allow us to pause here to wonder why Montemagno, no stranger to the back-biting culture of university campuses, failed to foresee that this would become a minor flap. …

It didn’t seem to occur to the members of the Editorial Board that Montemagno had successfully pulled off this feat in Alberta before arriving at SIU. Also, they seem unaware he took a pay cut of over $100,000 ($340,000 USD = $437,996.28 CAD as of March 2, 2018). That’s an awfully big pay cut even if it is in Canadian dollars.

In any event, I wish the folks at SIU all the best and I hope Dr. Montemagno proves to be a successful and effective chancellor. (It doesn’t look good when you hire your family but it doesn’t necessarily mean it’s wrong and, as for output from the Ingenuity Lab, everyone has a least one mistake and one failure in their working careers. For good measure, sometimes something that looks like a failure turns out to be a success. However, I think some questions need to be asked.

I offer my thanks to the student reporters at SIU’s The Daily Egyptian , Dawn Rhodes, and the Chicago-Tribune Editorial Board whose investigative reporting and commentary supplied me with enough information to go back and reappraise what I ‘knew’ about the Ingenuity Lab.

As for the Ingenuity Lab, perhaps we’ll hear more about their Carbon transformation programme later this year (2018). Unfortunately, the current webpage does not have substantive updates. There are some videos but they seem more like wistful thinking than real life projects.

To answer my own question, What is happening with Alberta’s (Canada) Ingenuity Lab? The answer would seem to be, not much.

If they are cleaning up a mess and this looks like it might be the case, I hope they’re successful and can move forward with their projects. I would like to hear more about the Ingenuity Lab in the future.

*’Natural Resource Canada’ corrected to ‘Natural Resources Canada’ on April 25, 2018.

BIODESIGN : Nature + Science + Creativity call for artists and a job posting (Rhode Island School of Design)

Leave a reply

h/t @raymondsbrain (Raymond Nakamura) for this item from the Rhode Island School of Design (RISD) BIODESIGN: Nature + Science + Creativity call for proposals webpage,

OPEN CALL for Proposals

Exhibition: Biodesign : From Inspiration to Integration

Venue: Rhode Island School of Design (RISD)

Submit your Biodesign or Bioart projects or ideas for programs and workshops

Funding available for production and transportation

Deadline for proposals: March 15, 2018

Curated by: William Myers & The Nature Lab @ RISD

Exhibition Dates: August 25 through September 27, 2018

Click [here] to download guidelines

Summary: The exhibition will showcase recent examples of design and art that help reform our relationship with nature, moving it from a destructive to a more integrated, mutually beneficial model. Major themes will include collaboration and co-creativity, presenting emerging best practices for working with living materials and with experts across fields. The presentation of approximately 20 projects will accompany programming including workshops, lectures, and panel discussions. This exhibition will welcome audiences curious about new experiments in designing, manufacturing and building that prioritize biodiversity protection and highlight new artistic practices that integrate biological processes or reflect on advances in the life sciences.​

I followed the link to the guidelines and found some additional information,

The Nature Lab at RISD is pleased to announce Biodesign: From Inspiration to Integration, an exhibition curated by William Myers to mark the closing of our 80th anniversary celebrations. The exhibition will open in Spring 2018 and showcase recent examples of design and art that help reform our relationship with nature, moving it from a destructive to a more integrated, mutually beneficial model.

…

Please submit a 1–4 page summary of the work you propose for the exhibition, including
3 supporting images, via email. Also attach a current CV to your message and be sure to include your website or portfolio if applicable. Include any estimates of production, shipping or other related expenses for the project. Please keep the e-mail size under
10MB and include “RISD Exhibition Proposal” and your last name in the subject line. This call is open to everyone. Applicants can expect a response before the end of April [2018].

There is also a job, which is paid, part-time, and remote,

We are seeking a Curatorial Assistant to develop the exhibition. It is a paid, part-time post that can be located anywhere. Deadline to apply is March 2nd [2018]. Description here.

The Canadian Science Policy Conference in Ottawa (for the fourth year in a row but who’s counting?), November 7 – 9, 2018

Leave a reply

Honestly, four years of holding a national conference in Ottawa, Ontario? Perhaps they could call it the Ottawa-Canadian Science Policy Conference. (loud sigh from the other side of the country)

Mild ire aside, this will be the 10th year for the conference and the founders and organizers should be congratulated on their extraordinary efforts. Given how difficult it is to organize national organizations anywhere, let alone in Canada, and the dearth of active national science organizations, the folks behind the Canadian Science Policy Conference should be lauded. The first and most prominent name that jumps to mind is Mehrdad Hariri* although I’m sure there are others. Happy 10th Anniversary!

From a February 14, 2018 CSPC announcement (received via email),

CSPC 2018: Building Bridges Between Science, Policy, and Society

CSPC is excited to announce the 10th Canadian Science Policy Conference (CSPC 2018) will be held in Ottawa, Ontario, on November 7-9th, 2018, at the Delta Hotel!

To celebrate the 10th anniversary of CSPC, scientists, entrepreneurs, policy-makers, politicians, journalists, students and many others from across the country are invited to the nation’s capital.

Join us to explore, discuss, exchange ideas, and mobilize knowledge regarding the present and future of Canadian science, technology, and innovation policy. For more information visit our website at www.sciencepolicy.ca 

Call for Panel Proposals

The CSPC 2018 call for panel proposals is now open! Proposals can be in a variety of presentation formats that revolve around any of the conference themes. The diversity of presentation formats throughout the conference makes it possible for delegates and organizations to share their thoughts, views, and experiences in an interactive and engaging manner. Proposals by organizations and individuals from across all sectors and disciplines are welcome.

Here are the CSPC 2018 Themes:

  • Science and Policy
  • Science and Society
  • Science, Innovation, and Economic Development
  • Science and International Affairs
  • Science and The Next Generation

The deadline for submitting proposals is April 13, 2018.\

Click here to learn more about the submission criteria!

They’re asking for 2018 conference volunteers,

Call for CSPC 2018 Volunteers

CSPC 2017 was the best conference yet and planning for CSPC 2018 to make it even better is already underway. You can make an impact in Canadian science policy and a significant contribution to positive change and innovation by answering the call for volunteers today!

Make sure you seize this great opportunity to learn more about the interface of science and policy.

Click here to learn more about becoming a volunteer!

There’s also a request for essays on the 2018 Canadian federal budget,

Contribute to CSPC’s featured editorial:
“Science and Innovation in the Federal Budget 2018”

There is great anticipation for the Federal budget 2018 in the science and innovation community. CSPC invites you to write an opinion piece for the upcoming CSPC featured editorial.

The deadline for submission is Friday, March 2, 2018.

Articles must be 600 – 800 words and sent to editorial@sciencepolicy.ca. Articles will be published on the CSPC website and will be widely shared in CSPC social media channels as well as in the upcoming newsletters.

Click here to see the past CSPC featured editorials

Finally, there’s a trailer for Neil Turok’s 2017 conference keynote address (Turok is the director for the Perimeter Institute for Theoretical Physics and his whole talk will be available soon),


I once went a talk by Dr. Turok and I’m glad to see he’s not relying on his written notes to the point where he seems to be reading in doubletime so he can be finished.

I am getting a little tired of hearing about how great Canada is and this talk seems self-aggrandizing in currently fashionable language. Well, perhaps I’m just feeling the embarrassment of watching the Trudeau family traipse around India on an official trip in a variety of costumes that seem dated and over the top.

*Mehrdad Harirri corrected to Mehrdad Hariri on November 1, 2018.