Monthly Archives: November 2013

Grand Challenges Canada funds 83 projects to improve global health

For the third year in a row (as per my Dec. 22, 2011 posting and my Nov. 22, 2012 posting), I’m featuring Grand Challenges Canada funding for its ‘Stars in Global Health’ programme . From the Grand Challenges Canada (GCC) Nov. 21, 2013 news release,

Imaginative: 83 Bold Innovations to Improve Global Health Receive Grand Challenges Canada Funding

Among novel ideas to reduce disease, save lives in developing world:
Diagnostic diapers to detect deadly rotavirus; Rolling water barrel;
Special yogurt offsets pesticides, heavy metals, toxins in food;
Inventive shoe, boot material releases bug repellent when walking

50 innovators from low- and middle-income countries,
plus 33 from Canada, share $9.3 million in seed grants

Grand Challenges Canada, funded by the Government of Canada, today extends seed grants of $100,000 each to 83 inventive new ideas for addressing health problems in resource-poor countries.

The Grand Challenges Canada “Stars in Global Health” program seeks breakthrough and affordable innovations that could transform the way disease is treated in the developing world — innovations that may benefit the health of developed world citizens as well.

Of the 83 grants announced today, 50 are given to innovators in 15 low- and middle-income nations worldwide and 33 to Canadian-originated projects, to be implemented in a total of 30 countries throughout the developing world.

“Innovation powers development leading to better health and more jobs. I feel proud that Canada, through Grand Challenges Canada, has supported almost 300 bold ideas to date in our Stars in Global Health program,” says Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada.  “This is one of the largest pipelines of innovations in global health in the world today.”

Says the Honourable Christian Paradis, Canadian Minister of International Development and Minister for La Francophonie: “Grand Challenges Canada’s portfolio of projects shows how innovators with bold ideas have the potential to make a big impact on global health.  By connecting game-changing ideas with some of the most pressing global health challenges, these projects will lead to sustainable and affordable health solutions in low- and middle-income countries.”

The portfolio of 83 creative, out-of-the-box ideas, selected through independent peer review from 451 applications, includes projects submitted by social entrepreneurs, private sector companies and non-government organizations as well as university researchers.  Among them:

Diagnostics

  • A simple, portable, dry, yeast-based blood screening test (Belize, Jamaica).  WHO estimates almost half of 46 million blood donations in low-income countries are inadequately tested;  in Africa up to 10% of new HIV infections are caused by transfusions.  A University of Toronto-developed yeast-based blood screening tool will detect combinations of diseases. Like baking yeast, it can be stored dry, and can be grown locally with minimal equipment and training, improving accessibility in rural areas.
  • A bedside, Litmus paper-like test to detect bronchitis (Brazil, India). Being pioneered at McMaster University with international collaborators, a simple sputum test will detect infectious and allergic bronchitis in adults and children, reducing mis-diagnosis in developing countries and saving resources: time, steroids, antibiotics.

Water, sanitation, hygiene and general health

  • Special yogurts formulated to offset the harm to health caused by heavy metals, pesticides and other toxics in food (Africa).  Between 2006-2009 in Nairobi, only 17% of the total maize sampled and 5% of feed was fit for human and animal consumption respectively. University of Western Ontario researchers have developed novel yogurts containing a bacteria that, in the stomach, sequesters certain toxins and heavy metals and degrades some pesticides.
  • Addressing arsenic-laced groundwater. In Bangladesh, 1 in 5 deaths (600,000 per year) occur due to groundwater arsenic, dubbed by WHO as the largest mass poisoning in history, with some 77 million people at risk.  Project 1) Toronto-based PurifAid will deploy new filtration units via franchised villagers who will filter and deliver purified water, perform maintenance, acquire new filters and dispose of old ones, which can be used to produce biofuels.  Project 2) A project based at the University of Calgary, meanwhile, will work to increase the use of Western Canadian lentils in Bangladeshi diets.  The crop is rich in selenium, which can decrease arsenic levels and improve health.
  • “WaterWheel” (India, Kenya, Mongolia).  This simple, innovative device from India is a wheeled water container that enables the collection and transport of 3 to 5 times as much water as usual per trip, as well as hygienic storage, saving valuable time for productive activities and improving health.

Malaria

  • A vaccine based on a newly-discovered antibody in men that prevents malaria infection in the placenta (Benin, Colombia).  Colombian men exposed to malaria are found to have antibodies that can prevent infection in the placenta of a pregnant woman. This University of Alberta finding forms the basis for developing a novel vaccine against several forms of malaria, which cause 10,000 maternal deaths and 200,000 stillbirths annually.
  • Insect-repellent clothing, footwear and wall plaster (East Africa).  1) In Tanzania, the Africa Technical Research Institute will lead the design and manufacture of attractive, affordable insecticide-treated clothing while 2) the Ifakara Health Institute will develop anti-mosquito footwear material that slowly releases repellents from the friction of walking.  A key advantage: no compliance or change in habits required.  3) Uganda’s Med Biotech Laboratories, meanwhile, will produce a colorful, insecticide-infused ‘plaster’ for the outside walls of African village homes.

Maternal and child health

  • Mothers Telling Mothers: improving maternal health through storytelling (Uganda).  Work by Twezimbe Development Association has found that stories told by mothers in their own words and reflecting shared realities are most likely to increase the number of moms seeking skilled health care, and convince policymakers to improve healthcare access.  This project will capture 3 to 5 minutes stories to be shared through digital media platforms and health clinics.

Mobile technology

  • Digital African Health Library (Sub-Saharan Africa).  The University of Calgary-led project is creating an app to support bedside care by medical doctors in Africa: a smartphone-accessible resource providing evidence-based, locally-relevant decision support and health information.  A pilot involving 65 doctors in Rwanda showed point of care answers to patient questions more than tripled to 43%, with self-reported improvement in patient outcomes.

Health care

  • Simple sticker helps track clean surfaces in healthcare facilities (Philippines).  WHO estimates that 10% to 30% of all patients in developing country health care facilities acquire an infection.   An innovative sticker for hospital surfaces developed by Lunanos Inc. changes colour when a cleaner is applied and fades color after a predetermined period of time, helping staff track and ensure cleanliness of equipment and other frequently touched surfaces.
  • “Mystery clients” to assess and improve quality of TB care (India).  India accounts for 25% of global tuberculosis (TB) incidence.  To evaluate variations in practice quality, and identify ways to improve TB management in India, this project, led by Canada’s McGill University, will send researchers into clinics posing as a patient with standard TB symptoms.  The project builds on earlier work related to angina, asthma and dysentery, which revealed incorrect diagnoses and treatment.

And many more.

A complete set of 83 short project descriptions, with links to additional project details, available photos / video, and local contact information, is available in the full news release online here: http://bit.ly/HOLt5b

Here’s a video for the one of the projects (filtering arsenic out of Bangladesh’s water),

I chose this project somewhat haphazardly. It caught my attention as I have written more than once about purification efforts and as it turns out, this is a Canada-based project (with a Bangladeshi partner, BRAC) from the University of Toronto.

You may have heard the video’s narrator mention scotch whiskey, here’s why (from the YouTube page hosting the project video,page),

We plan to roll out a new generation of filtration units which run on an organic by-product of the beverage industry. The units address many of the failings of existing devices (they require no power or chemicals and are very low maintenance).

This project gets still more interesting (from the full project description page),

Device for the Remediation and Attenuation of Multiple Pollutants (DRAM) removes 95% of arsenic from contaminated water within 5 minutes of exposure. With an estimated 600,000 deaths directly attributable to arsenic poisoning every year, these units hold the potential to save millions of lives. Existing solutions are too complicated and suffer from significant usability issues (2012 UNICEF study).

We will deploy our units through a franchise business model. [emphasis mine] Local villagers will filter and deliver purified water, perform maintenance, acquire new media, and dispose spent media. The current market leader, the Sono Filter, has less than 20% uptake (according to UNICEF). DRAM costs only 25% of this solution, has lower maintenance requirements (4-6 month media cycle vs. 2 week media cycle), higher durability, and can be retrofitted onto existing tube wells villagers use thereby requiring no behavior change. The spent media (which must be replaced every 4-6 months) can be used to produce biofuels, giving PurifAid a decisive capability over competitors.

With the assistance of our local partner BRAC (ranked #1 on Global Journal’s list of top NGOs in 2012) we will retrofit our units onto existing tubewells. Contaminated water is pumped from the tubewell into the unit where it passes into the bottom of the unit, rising up through a bed of the organic filter media, binding the arsenic. Clean water is displaced and forced out of the top of the unit and out through the built-in tap. Our community based solution will begin with a proof-of-concept installation in the Mujibnagar District (pop. 1.3 million). BRAC will assist in testing our filter water quality on the ground and these results will be used to obtain regulatory approval for our technology. We will then operationalize our community-run DRAM systems. A council of local stakeholders will nominate prospective franchisees amongst villagers. These villagers will replace filter media in 4 month intervals and order annual delivery of new media. We are securing partnerships with nearby distilleries to locally source the filter media. [emphasis mine] Disposal will be handled by a local caretaker who will store spent media in bulk before transferring it for use as biofuel. Caretaker salary, media sourcing, and delivery costs will be paid by charging a levy on customer households. PurifAid will monitor behavioural and health indicators to ascertain DRAM’s immediate and long-term impact. To this end PurifAid has partnered with Ashalytics, a start-up global health analytics company, to report operational issues, measure impact, and communicate important metrics to key staff and stakeholders via mobile phones. This results in an environmentally-friendly value chain that uses beverage industry waste, maximizing positive impact. If the Bangladesh installations are a success then this system can be introduced across the Indian subcontinent and in west Africa, where arsenic in groundwater poses a serious health problem. DRAM has the potential to improve the lives of millions globally.

After 18 months we envisage having installed 15 DRAM systems supplying 45 liters of purified water per day to 2,700 households. In order to ensure maintenance, 15 paid caretakers will operate the pumps and a driver will supply the caretakers with fresh media every 4-6 months. Biannually, new bulk media will be provided to storage unit in the village, spent media will in turn be taken to a plant and converted to biofuel. Villagers will invest collectively to purchase, install and operate DRAM on pre-existing tube wells – thus no behavioral changes needed.

Our filters employ a new water filtration technology. Our franchise model involves social and business innovation, empowering communities to manage their own water treatment under the stewardship of a local partner that manages 17 social businesses with combined annual revenues of $93m in 2011.

(Aside: Don’t they ask for a ‘dram’ of whiskey in the movies?) This project is intended to do more than purify water; it’s designed to create jobs. Bravo!

Now back to the news release for details about the countries and agencies involved,

The global portfolio of grants, broken down by region and country:

30 projects based in 6 African countries (16 in Kenya, 5 in Tanzania, 5 in Uganda, 2 in Nigeria and 1 each in Senegal and Ghana)
17 projects based in 7 countries in Asia (7 in India, 2 in Pakistan 4 in Thailand and 1 each in Bangladesh, Cambodia, Mongolia and the Philippines)
Two projects based in South America (Peru) and one in Europe (Armenia)
33 projects based in 11 Canadian cities (14 in Toronto, 3 each in Calgary, Montreal and Vancouver, 2 each in Winnipeg, Edmonton and London, and 1 each in Halifax, Hamilton, Ottawa and Saskatoon)

The Canadian-based projects will be implemented worldwide (a majority of them implemented simultaneously in more than one country):

15 countries in Africa (5 in Kenya, 4 in Tanzania, 3 each in Uganda and Ethiopia, 2 each in Rwanda, Somalia, South Africa, South Sudan, and Zambia, and 1 each in Benin, Botswana, Ghana,  Malawi, Nigeria, and DR Congo)
8 countries in Asia (8 in India, 6 in Bangladesh, 1 each in Bhutan, China, Nepal, Pakistan, Philippines and Thailand)
5 countries in South and Latin America (Belize, Brazil, Colombia, Jamaica, Peru.) and
1 in the Middle East (Egypt)

Including today’s grants, total investments to date under the Grand Challenges Canada “Stars in Global Health” program is $32 million in 295 projects.

For full details: http://bit.ly/HOLt5b

* * * * *

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global

health. We are funded by the Government of Canada through the Development Innovation Fund announced in the 2008 Federal Budget. We fund innovators in low- and middle-income countries and Canada. Grand Challenges Canada works with the International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR), and other global health foundations and organizations to find sustainable, long-term solutions through Integrated Innovation − bold ideas that integrate science, technology, social and business innovation. Grand Challenges Canada is hosted at the Sandra Rotman Centre.

Please visit grandchallenges.ca  and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Canada’s International Development Research Centre

The International Development Research Centre (IDRC) supports research in developing countries to promote growth and development. IDRC also encourages sharing this knowledge with policymakers, other researchers and communities around the world. The result is innovative, lasting local solutions that aim to bring choice and change to those who need it most. As the Government of Canada’s lead on the Development Innovation Fund, IDRC draws on decades of experience managing publicly funded research projects to administer the Development Innovation Fund. IDRC also ensures that developing country researchers and concerns are front and centre in this exciting new initiative.

www.idrc.ca

About Canadian Institutes of Health Research

The Canadian Institutes of Health Research (CIHR) is the Government of Canada’s health research investment agency. CIHR’s mission is to create new scientific knowledge and to enable its translation into improved health, more effective health services and products, and a strengthened Canadian health care system. Composed of 13 Institutes, CIHR provides leadership and support to more than 14,100 health researchers and trainees across Canada. CIHR will be responsible for the administration of international peer review, according to international standards of excellence. The results of CIHR-led peer reviews will guide the awarding of grants by Grand Challenges Canada from the Development Innovation Fund.

www.cihr-irsc.gc.ca

About the Department of Foreign Affairs, Trade and Development Canada

The mandate of Foreign Affairs, Trade and Development Canada is to manage Canada’s diplomatic and consular relations, to encourage the country’s international trade, and to lead Canada’s international development and humanitarian assistance.

www.international.gc.ca

About Sandra Rotman Centre

The Sandra Rotman Centre is based at University Health Network and the University of Toronto. We develop innovative global health solutions and help bring them to scale where they are most urgently needed. The Sandra Rotman Centre hosts Grand Challenges Canada.

www.srcglobal.org

I have found it confusing that there’s a Grand Challenges Canada and the Bill and Melinda Gates Foundation has a Grand Challenges programme, both of which making funding announcements at this time of year. I did make some further investigations which I noted in my Dec. 22, 2011 posting,

Last week, the Bill & Melinda Gates Foundation announced a $21.1 M grant over three years for research into point-of-care diagnostic tools for developing nations. A Canadian nongovermental organization (NGO) will be supplementing this amount with $10.8 M for a total of $31.9 M. (source: Dec. 16, 2011 AFP news item [Agence France-Presse] on MedicalXpress.com)

At this point, things get a little confusing. The Bill & Melinda Gates Foundation has a specific program called Grand Challenges in Global Health and this grant is part of that program. Plus, the Canadian NGO is called Grand Challenges Canada (couldn’t they have found a more distinctive name?), which is funded by a federal Canadian government initiative known as the Development Innovation Fund (DIF). …

Weirdly, no one consulted with me when they named the Bil & Melinda Gates Foundation programme or the Canadian NGO.

GUMBOS, the nanoparticle kind

The American Chemical Society (ACS) has posted its latest episode (GUMBOS; an interview with Isiah Warner) of the Prized Science podcast series according to a Nov. 19, 2013 news release on EurekAltert,

A group of nanoparticles called “GUMBOS” is as varied as their culinary namesake implies, with a wide range of potential applications from cancer therapy to sensors. GUMBOS are the focus of a new video from the American Chemical Society’s (ACS) Prized Science series. The videos are available at http://www.acs.org/PrizedScience.

The latest episode of Prized Science features Isiah Warner, Ph.D., this year’s winner of the ACS Award in Analytical Chemistry, sponsored by the Battelle Memorial Institute. He is a Boyd Professor of Chemistry at Louisiana State University. Among other research, the award recognizes Warner’s work developing GUMBOS, which is an acronym for “Group of Uniform Materials Based on Organic Salts.” In the video, Warner explains that the versatility of these nanoparticles, which are about 1/100,000th of the width of a human hair, comes from the ability to mix, match and tailor them to specific features for which a researcher is looking.

The next and final episode in the 2013 series of Prized Science features Esther Takeuchi, Ph.D., winner of the E. V. Murphee Award in Industrial and Engineering Chemistry.

Other episodes feature Tim Swager, Ph.D., winner of the 2013 ACS Award for Creative Invention; Peter J. Stang, Ph.D., winner of the 2013 ACS Priestley Medal; Greg Robinson, Ph.D., winner of the 2013 F. Albert Cotton Award; and Shirley Corriher, winner of the 2013 James T. Grady-James H. Stack Award for Interpreting Chemistry for the Public.

ACS encourages educators, schools, museums, science centers, news organizations and others to embed Prized Science on their websites. The videos discuss scientific research in non-technical language for general audiences. New episodes in the series, which focuses on ACS’ 2013 national award recipients, will be issued periodically.

The 2013 edition of Prized Science features renowned scientists telling the story of their own research and its impact and potential impact on everyday life. Colorful graphics and images visually explain the award recipient’s research.

The ACS administers more than 60 national awards to honor accomplishments in chemistry and service to chemistry. The nomination process involves submission of forms, with winners selected by a committee consisting of ACS members who typically are technical experts in the nominee’s specific field of research.

Here is the GUMBOS podcast,


Here is the video description and full credit list provided by the ACS (from the YouTube page hosting the video).

Uploaded on Nov 18, 2013

A group of nanoparticles called “GUMBOS” is as varied as their culinary namesake implies, with a wide range of potential applications from cancer therapy to sensors. The latest episode of Prized Science features Isiah Warner, Ph.D., this year’s winner of the ACS Award in Analytical Chemistry. Among other research, the award recognizes Warner’s work developing GUMBOS, which is an acronym for “Group of Uniform Materials Based on Organic Salts.” In the video, Warner explains that the versatility of these nanoparticles, which are about 1/100,000th of the width of a human hair, comes from the ability to mix, match and tailor them to have the specific features that scientists might need for different applications.

Produced by the American Chemical Society
Video by XiaoZhi Lim
Animation by Sean Parsons

As far as I know, there’s only one song that features gumbo in its lyrics, Jambalaya by Hank Williams. Here’s a somewhat bouncy version by John Fogerty,

Enjoy!

Renewable, green alternative to oil from Israel’s Ben Gurion University

A November 20, 2013 news item on Nanowerk features a new technique for creating an alternative fuel developed by researchers at Ben Gurion University of the Negev (BGU) in Israel,

Ben-Gurion University of the Negev (BGU) researchers have developed an innovative process to convert carbon dioxide and hydrogen into a renewable alternative for crude oil, which could transform fuels used in gas and diesel-powered vehicles and jets.

The “green feed” crude oil can be refined into renewable liquid fuels using established technologies and can be transported using existing infrastructure to gas stations. The highly efficient advance is made possible in part using nanomaterials that significantly reduce the amount of energy required in the catalytic process to make the crude oil.

A November 13, 2013 BGU news release provides more detail,

As opposed to other alternative fuel sources, such as electric cars, which require additional infrastructure, this green feed would merely replace oil as the input for refineries. [Moti] Herskowitz, the incumbent of the Israel Cohen Chair in Chemical Engineering, is also the VP & Dean of R&D at BGU.  [sic]

The process is patent pending, “and we are ready to take off,” demonstrate and commercialize it, asserts Herskowitz. Bench experiments have been conducted and scale-up should be relatively simple, he says. …

“It is an extraordinary challenge to convert carbon dioxide and hydrogen to green feed,” he says, “The technology is based on novel specially tailored catalysts and catalytic processes. Well-established, commercially available technology can be directly applied to the process developed at BGU. It is envisaged that the short-term implementation of the process will combine synthetic gas produced from various renewable and alternative sources with carbon dioxide and hydrogen. Since there are no foreseen technological barriers, the new process should become a reality within five to ten years,” he says.

Noting that Prime Minister Binyamin Netanyahu has made it clear that one of the national priorities of the State of Israel is to develop alternatives to oil, Herskowitz believes that, “As technological breakthroughs, such as carbon dioxide capture from various sources including air and water splitting, become technologically and economically feasible, this process will become the dominant technology for production of liquid fuels.”

Regarding other alternative fuels, Herskowitz maintains that his invention represents a game-changer. “The liquids that have been used over the past decade are ethanol (alcohol), biodiesel and/or blends of these fuels with conventional fuels, as will continue to be done in the foreseeable future. These alternatives are, however, far from ideal, and there is a pressing need for a game-changing approach to produce alternative drop-in liquid transportation fuels by sustainable, technologically viable and environmentally acceptable (in terms of GHG emission) processes from abundant, low-cost, renewable materials,” he says.

The Blechner Center for Industrial Catalysis and Process Development has a proven track record of commercializing applications from its basic research. It developed the Aleol product line of fine aroma chemical products which Makhteshim-Agan has set up Negev Aroma at Neot Hovav to produce.

The news item on Nanowerk offers a brief description of the technology developed at BGU<

The BGU crude oil process produces hydrogen from water, which is mixed with carbon dioxide captured from external sources and synthetic gas (syngas). This green feed mixture is placed into a reactor that contains a nano-structured solid catalyst, also developed at BGU, to produce an organic liquid and gas.

For anyone who’d like some additional information and an Israeli perspective on this work, there’s a Nov. 19, 2013 article by David Shamah for The Times of Israel (Note: Links have been removed from the excerpt),,

While everyone agrees that alternatives to fossil fuels are needed, currently available alternatives require such a major an adjustment in manufacturing and social infrastructure so as to render the whole project untenable.

Besides, said Professor Moti Herskowitz of Ben-Gurion University of the Negev, even if the world could be convinced to replace internal combustion engines in cars and trucks with engines that run on electricity, methanol, or other gasoline replacements, there remains one major problem. “If you notice, no one ever discusses alternative fuels for jets. No one wants a problem in the air, which makes jet fuel irreplaceable right now,” Herskowitz said.

Considering the fact that over 10% of crude oil is used for jet fuel, it appears that refined oil is going to be around for a long time.

If you can’t beat ‘em, then join ‘em, says Herskowitz. …

“It is envisaged that the short-term implementation of the process will combine synthetic gas produced from various renewable and alternative sources with carbon dioxide and hydrogen,” he [Herskowitz] said at the event. “Since there are no foreseen technological barriers, the new process should become a reality within five to ten years.”

The main issue at this point, said Herskowitz, is developing a cheaper way to extract the hydrogen gas. The technology to do this is well-known, and hydrogen is used to power cars, buses and trucks in many places, but current extraction methods are not cost efficient. The most promising method to produce large quantities of hydrogen at a commercially viable price, said Herskowitz, lies in splitting water (hydrogen and oxygen), extracting the hydrogen component as a gas, and pushing it into the green feed. “We are positive we can do produce hydrogen more cheaply,” Herskowitz said.

Acquiring the carbon dioxide needed for the process, he said, was sadly, very simple, as that pollutant, found in smokestack emissions from refineries, and power, steel and cement plants, is all too common.

Does this method of producing gasoline have a chance against Big Oil? After all, there are plenty of urban legend-type stories about oil companies suppressing methods that claim to turn water into gasoline. …

I recommend reading Shamah’s article for the context he provides about the issues surrounding the use of alternative fuels.

Chaos, brains, and ferroelectrics: “We started to see things that should have been completely impossible …”

Given my interest in neuromorphic (mimicking the human brain) engineering, this work at the US Oak Ridge National Laboratories was guaranteed to catch my attention. From the Nov. 18, 2013 news item on Nanowerk,

Unexpected behavior in ferroelectric materials explored by researchers at the Department of Energy’s Oak Ridge National Laboratory supports a new approach to information storage and processing.

Ferroelectric materials are known for their ability to spontaneously switch polarization when an electric field is applied. Using a scanning probe microscope, the ORNL-led team took advantage of this property to draw areas of switched polarization called domains on the surface of a ferroelectric material. To the researchers’ surprise, when written in dense arrays, the domains began forming complex and unpredictable patterns on the material’s surface.

“When we reduced the distance between domains, we started to see things that should have been completely impossible,” said ORNL’s Anton Ievlev, …

The Nov. 18, 2013 Oak Ridge National Laboratory news release, which originated the news item, provides more details,

“All of a sudden, when we tried to draw a domain, it wouldn’t form, or it would form in an alternating pattern like a checkerboard.  At first glance, it didn’t make any sense. We thought that when a domain forms, it forms. It shouldn’t be dependent on surrounding domains.”  [said Ievlev]

After studying patterns of domain formation under varying conditions, the researchers realized the complex behavior could be explained through chaos theory. One domain would suppress the creation of a second domain nearby but facilitate the formation of one farther away — a precondition of chaotic behavior, says ORNL’s Sergei Kalinin, who led the study.

“Chaotic behavior is generally realized in time, not in space,” he said. ”An example is a dripping faucet: sometimes the droplets fall in a regular pattern, sometimes not, but it is a time-dependent process. To see chaotic behavior realized in space, as in our experiment, is highly unusual.”

Collaborator Yuriy Pershin of the University of South Carolina explains that the team’s system possesses key characteristics needed for memcomputing, an emergent computing paradigm in which information storage and processing occur on the same physical platform.

Memcomputing is basically how the human brain operates: [emphasis mine] Neurons and their connections–synapses–can store and process information in the same location,” Pershin said. “This experiment with ferroelectric domains demonstrates the possibility of memcomputing.”

Encoding information in the domain radius could allow researchers to create logic operations on a surface of ferroelectric material, thereby combining the locations of information storage and processing.

The researchers note that although the system in principle has a universal computing ability, much more work is required to design a commercially attractive all-electronic computing device based on the domain interaction effect.

“These studies also make us rethink the role of surface and electrochemical phenomena in ferroelectric materials, since the domain interactions are directly traced to the behavior of surface screening charges liberated during electrochemical reaction coupled to the switching process,” Kalinin said.

For anyone who’s interested in exploring this particular approach to mimicking the human brain, here’s a citation for and a link to the researchers’ paper,

Intermittency, quasiperiodicity and chaos in probe-induced ferroelectric domain switching by A. V. Ievlev, S. Jesse, A. N. Morozovska, E. Strelcov, E. A. Eliseev, Y. V. Pershin, A. Kumar, V. Ya. Shur, & S. V. Kalinin. Nature Physics (2013) doi:10.1038/nphys2796 Published online 17 November 2013

This paper is behind a paywall although it is possible to preview it for free via ReadCube Access.

*Four Vancouver (Canada) science events: Policy Making and Science; Solving a global medical crisis with a particle accelerator; and Marc Garneau asks, Should Canada be in space?; light to quantum materials

It’s going to be busy in Vancouver (Canada) next week, if you plan your life around the city’s science events.

The first event, “The Art of Policy Making: What’s Science Got to Do With It?” is being held by the Canadian Association for the Advancement of Science. It will be held at lunchtime on Tuesday, November 26, 2013 at Simon Fraser University’s Harbour Centre campus in downtown Vancouver.

The Art of Policy Making:

What’s Science Got to Do With It?

Speaker: Andrew Petter, President of Simon Fraser University

Panelists: Adam Walters-Navigate Surgical Company, Vancouver, B.C. and David S. Fushtey, Senior Fellow,, Centre for Corporate Governance and Risk Management, SFU Beedie Faculty of Business, and Fellow, SFU Centre for Dialogue

Moderator: Bill Good, CKNW Radio, Vancouver, B.C.

Co-Chairs: Martin Zuckermann, D.Phil. (Oxon), FRSC, Emeritus Professor of Physics, McGill University

Olga A. Barrat, Ph.D., Research Scientist

Date: November 26, 2013

Location:
Simon Fraser University
Harbour Centre / Segal Centre
515 West Hastings, Vancouver
Registration: 11:30 a.m.
Presentation: 12:10 p.m.
Discussion: 12:50 – 1:45 p.m.

Pre-register via email at: caas@caas-acascience.org
Or by post to CAAS at the address or fax number noted below
Tickets: $35.00 (payable at the door by cash or cheque)
Information: caas@caas-acascience.org

For that price I hope they are including lunch. I did not realize we had a Canadian Association for the Advancement of Science (established in 1999) or that it was located in North Vancouver,

CANADIAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE
P.O. Box 75513, 3034 Edgemont Blvd., North Vancouver, B.C., Canada V7R 4X1 / Fax: 604-926-5806
www.caas-acascience.org

The next day, you can trot off to: ‘Medicine Accelerated: Canada’s role in the Medical Isotope Revolution’ (part of the Unveiling the Universe Lecture Series) will be held on Wednesday, 27 November 2013 from 7:00 PM to 9:00 PM (PST) at Vancouver’s Science World., From the Nov. 15, 2013 TRIUMF;Canada’s National Laboratory for Particle and Nuclear Physics news release,

Medicine Accelerated: Canada’s role in the Medical Isotope Revolution

Join Science World and TRIUMF in welcoming Dr. Paul Schaffer for a free public lecture at the TELUS World of Science Wednesday November 27, 2013.  As part of the “Unveiling the Universe” lecture series presented by TRIUMF and Science World, Dr. Schaffer will be speaking about recent advances in radiopharmaceuticals and and their role in the diagnosis, treatment, and management of diseases such as cancer and Alzheimer’s. he also will be highlighting Canada’s leadership role in developing cyclotron particle-accelerator technology to create medical isotopes.  This lecture is offered in cooperation with ARPICO, the Society of Italian Researchers and Professionals in Western Canada. (www.arpico.ca).

Tickets are free but registration is required.

Visit http://medicine-accelerated.eventbrite.ca  to reserve your seat.

Doors open at 6pm with the lecture starting at 7pm.   There will be a Q&A session to follow.

A live webcast of the lecture will be available online (requires Silverlight plugin). Visit registration site for link.

About Paul Schaffer

Paul Schaffer is the Division Head of the Nuclear Medicine program at TRIUMF, Canada’s national lab for particle and nuclear physics in Vancouver, BC. He is responsible for maintaining TRIUMF’s medical isotope and radiotracer production programs in support of neurological and oncological research. He was recently recognized as one of British Columbia’s Top Forty under 40 by Business in Vancouver magazine

About Science World

Science World British Columbia is a not-for-profit organization that engages British Columbians in science and inspires future science and technology leadership throughout our province.

About TRIUMF

TRIUMF is Canada’s national laboratory for particle and nuclear physics. It is owned and operated by a consortium of Canadian universities and is funded by a contribution through the National Research Council of Canada. The Province of British Columbia provides capital funding for the construction of buildings for the TRIUMF Laboratory.

There are some 23 General Admission tickets still available as of November 20, 2013 (9:15 am PST). This talk is likely to touch on TRIUMF’s recently ‘unveiled’ medical cyclotron (from my June 9, 2013 posting),

Today, Sunday, June 9, 2013, TRIUMF, Canada’s national laboratory for particle and nuclear physics, and its partners announced that they have devised a technique for producing medical isotopes that is not dependent on materials from nuclear reactors. From the June 9, 2013 TRIUMF news release,

With Canadian-developed tools and technology, a national team led by TRIUMF has reached a crucial milestone at the BC Cancer Agency in developing and deploying alternatives for supplying key medical isotopes. The team used a medical cyclotron that was designed and manufactured by Advanced Cyclotron Systems, Inc. (ACSI) of Richmond, BC, and successfully achieved large-scale production of technetium-99m (Tc-99m), sufficient for a metropolitan area.

The team announced the successful ramp-up of its technology to regularly produce enough of the critical Tc-99m isotope to supply an urban area the size of Vancouver. This achievement eliminates the need for nuclear reactors to produce isotopes, especially those that use weaponsgrade uranium, which has been the traditional approach.

ETA Nov. 25, 2013: There’s a Nov. 22, 2013 news item (Medical isotope supply interrupted across Canada; Delivery of one isotope to hospitals down to less than 50 per cent of normal) on CBC (Canadian Broadcasting Corporation) News online about the latest shortage of medical isotopes.

The third event is being hosted by Canadian Member of Parliament,(Liberal) Joyce Murray (Vancouver Quadra) on Friday, November 29, 2013 at Enigma Restaurant on W. 10th Avenue near the University of British Columbia. From the November 15, 2013, invitation,

Please join Member of Parliament Joyce Murray at her Friday November 29th MP Breakfast Connections discussion with guest speaker Marc Garneau, MP: “Does Canada need a Space Program?”

 Be part of the conversation with Canada’s first Astronaut and former President of Canada’s National Space Agency, Marc Garneau.  Canada’s Space Agency began in 1990, with a mission to lead the development and application of space knowledge for the benefit of Canadians and humanity.  Canadians have made significant contributions to space travel with the robotic Canadarm, developed in part here in British Columbia, by MacDonald Dettweiler, and we were all enthralled last year when Canadian Chris Hadfield was commander of the International Space Station and shared his experiences from space.  Is there a future for Canada’s  Space Agency?  Let’s ask Marc!

Details:

Friday, November 29, 2013

7:30 – Registration + Buffet Breakfast

7:50 – 8:45 Speaker + Q and A

Enigma Restaurant – 4397 W. 10th Ave. (Off Trimble) (map)

The cost of the breakfast is $20 / $10 for students.

(Cash only at the door)

Please RSVP to joyce.murray.c1c@parl.gc.ca or by calling 604-664-9220.

Interestingly, Canadian astronaut Chris Hadfleld has been in Vancouver giving interviews (Nov. 18, 2013 on The Rush television programme), as he’s been promoting his new book, An Astronaut’s Guide to Life on Earth. You can find out more about the book at http://chrishadfield.ca/

Btw, I have been to Joyce’s breakfasts before and they serve a good breakfast at Enigma.

*As of Nov. 20, 2013, 2:30 pm PDT: I’m adding one more event: Vancouver’s Café Scientifique is being held in the back room of the The Railway Club (2nd floor of 579 Dunsmuir St. [at Seymour St.], Vancouver, Canada), on Tuesday, November 26,  2013 at 7:30 pm. Here’s the talk description (from the Nov. 20,, 2013 announcement,

Our speaker for the evening will be Dr. Andrea Damascelli.

From Light Quanta to Quantum Materials

he photoelectric effect – the ejection of electrons from a solid consequent to the absorption of light – was discovered by Hertz in 1887 and explained by Einstein in 1905 on the basis of the revolutionary hypothesis of Light Quanta, or photons. This intuition, which gave Einstein the Nobel Prize in Physics in 1921, marked the beginning of quantum physics and also of photoelectric spectroscopy, one of the most active fields in modern science and technology. Owing to recent technical progress and in particular to the development of third generation synchrotron sources – particle accelerators in which electrons traveling at nearly the speed of light generate the most brilliant light available to scientists – the last decade witnessed a renaissance in this technique and its applications. These have now become the primary tools in the study of emerging Quantum Materials, systems which manifest a wide range of astonishing electronic and magnetic phenomena and with the potential to revolutionize consumer electronics, telecommunications, next-generation computing, alternative energy, and medicine.

You can find Dr. Damascelli’s profile page here on the University of British Columbia website.

Alberta gave its cellulose nanocrystal (or nanocrystalline cellolose) production plant a soft launch in September 2013

It’s been a little over two years since Alberta’s proposed cellulose nanocrystal (CNC), then called nanocrystalline cellulose (NCC), pilot plant was first announced (my July 5, 2011 posting). I gather that the plant was quietly opened in Sept. 2013. Finding a news release about the event has proved to be a challenge. The Alberta Innovates website does not list it in its Newsroom while the Alberta Innovates Technology Futures website does list a news release (September 12, 2013Alberta’s one-of-a-kind CNC pilot plant commissioned: Cellulose-based ‘wonder material’ now available to researchers, industry partnersf), despite numerous efforts on my part (try it yourself), I’m unable to access it. Happily, I was able to track down some information elsewhere.

First (in the order in which I found the information), there’s an Oct. 2, 2013 news item on the WorkingForest.com website submitted by Pulp and Paper Canada),

Alberta’s cellulose nanocrystals (CNC) pilot plant, which produces up to 100 kilograms of CNC per week, was commissioned in early September at Alberta Innovates-Technology Futures’ (AITF) Mill Woods facility before a crowd of researchers, industry leaders and government representatives.

The $5.5-million pilot plant, created through a collaboration of the governments of Canada and Alberta in partnership with industry under the Western Economic Partnership Agreement (WEPA), uses wood and straw pulp from plants such as flax and hemp to create CNC for testing in commercial applications that will lead to production.

“Alberta Innovates-Technology Futures is proud to host and operate Western Canada’s only CNC pilot plant,” said Stephen Lougheed, AITF’s president and CEO. “We’re able to provide researchers with more CNC than ever before, thereby accelerating the development of commercial applications.”

The grand opening of the CNC pilot plant’s is planned for 2014.

Then, there was more information about the plant and the event in Catherine Griwkowsky’s Sept. 12, 2013 article for the Edmonton Sun,

A new cellulose nanocrystals (CNCs) pilot plant will take wood and agricultural fires and turn it into a form that can make products stronger, give them sunlight-absorbing properties, add a negative electromagnetic charge and more.

The $5.5-million project in Mill Woods will churn out up to 100 kilograms of the crystals each week.

Technical Lead Frank Tosto said researchers will study various properties of the crystals, and work with an internal team as well as external industry and other researchers to transform knowledge of the properties into ideas for applications. Later, the team may experiment with unconventional sources of cellulose.

The CNCs can be used for drilling fluids, paints, industrial coatings, automotive components, building materials, plastics and packaging.

The process [of refining hemp, etc.] breaks down cellulose into smaller building blocks using a chemical process of acid hydrolysis, that separates crystal formations in cellulose from other structures. The width is between five to 10 nanometres with a length of 150 to 200 nanometers. To scale, cellulose fibre would be the size of a hockey rink and the nano crystal would be like a pen or pencil, he explained.

Ultimately, Tosto hopes they will find commercial applications for the CNCs. The pilot should last five to seven years. He said it’s hard to think outside the box when they don’t know where all the boxes are.

I’d love to know if any of the entrepreneurs who contacted me privately about accessing CNC so they could develop new applications are now able to purchase product from the Alberta plant or from the one in Quebec (CelluForce), which had a stockpile last I heard (my Oct. 3, 2013 posting). It seems odd to be building another plant when the country’s first such plant has stopped production. Meanwhile, there’s some action on the international scene. An Israeli startup company, Melodea has developed its own CNC/NCC extraction process and has received money to develop applications, from my Oct. 31, 2013 posting),

Melodea Ltd. is developing an economic ally viable industrial process for the extraction of NCC from the sludge of the paper industry, a waste stream produced at millions of tons around the world. The core of the novel technology was developed by the lab of Professor Oded Shoseyov from the Hebrew University of Jerusalem and was licensed exclusively to Melodea.

Moreover, the company develops unique technologies to self-assemble the NCC into ecologically friendly foams for industrial applications.

Melodea Ltd. announced today that it has been awarded above 1,000,000 Euro in 3 projects of the European Union Seventh Framework Program (FP7).

You’ll note Melodea’s process extracts CNC from the paper industry’s sludge which leads me to this question: will there be any discussion of this extracting CNC from sludge technique at the 2014 TAPPI (Technical Association for the Pulp, Paper, Packaging and Converting Industries) nanotechnology conference being held in Vancouver (Canada), June 23-26, 2014 (mentioned in my Nov. 14, 2013 posting about the conference’s submission deadline, Nov. 22, 2013)?

TED2014 Fellows announced and more about TED in Vancouver (Canada)

Technology, Entertainment, Design (TED), which is moving to Vancouver for two years starting in 2014, has announced its 21 2014 Fellows., I’ve excerpted biographies and links from just a few fellows, all of whom will be in Vancouver,

Andrew Bastawrous (Kenya | UK) – Eye surgeon + innovator
Kenya-based ophthalmologist who has created PEEK, a low-cost smartphone ophthalmic tool that delivers eye care in some of the world’s most challenging places, to those who need it most.

Steve Boyes (South Africa) – Conservation biologist
South African conservation biologist passionate about protecting African parrots and their forest habitat within the continent’s last remaining wilderness areas.

Aziza Chaouni (Morocco) – Architect + ecotourism specialist
Moroccan civil engineer and architect creating sustainable, built environments in the developing world, particularly in the deserts of the Middle East.

Shohini Ghose (Canada + India) – Quantum physicist + educator
Theoretical physicist who examines how the laws of quantum mechanics may be harnessed to develop next-generation computers and novel protocols like teleportation.

Erine Gray (USA) – Software developer
American software developer and founder of Aunt Bertha, a platform that instantly helps people find social services such as food banks, health care, housing and educational programs.

Shih Chieh Huang (Taiwan | USA) – Artist
Taiwanese-American artist who dissects and disassembles the mundane detritus of our lives – household appliances, lights, computer parts, toys, plastic objects – transforming them into surreal, animated “living” organisms.

Janet Iwasa (USA) – Molecular animator
Biochemist who uses 3D animation software to create molecular and cellular visualizations – such as how the HIV virus hijacks human cells – allowing researchers to visualize, explore and communicate their hypotheses.

Sergei Lupashin (Russia | USA | Switzerland) – Aerial robotics researcher + entrepreneur
Swiss-based engineer developing the Fotokite, an easy-to-use flying robotic camera. His work also includes unmanned aerial vehicles and autonomous cars.

David Sengeh (USA | Sierra Leone) – Biomechatronics engineer
Inventor of next-generation wearable mechanical interfaces that improve prosthetic comfort for amputees while simultaneously reducing costs, making the devices affordable in the developing world.

Shubhendu Sharma (India) – Reforestation expert
Indian industrial engineer restoring natural forests with his company, Afforestt, which offers a way to plant maintenance-free, wild and highly biodiverse forests using specialized afforestation methodology, research and cutting-edge technologies.

Robert Simpson (UK) – Astronomer + web developer
British astronomer who creates online platforms to cultivate a community of citizen science volunteers worldwide – crowdsourcing science. Projects cover a wide range of disciplines, from hunting for exoplanets to decoding whale language to mapping the Milky Way.

Bora Yoon (USA | South Korea) – Musician + sound architect
Korean-American vocalist, multi-instrumentalist and composer who creates immersive audiovisual soundscapes using digital devices, voice, and found objects and instruments from a variety of cultures and centuries. She evokes memory and association to formulate a cinematic storytelling through music and sound design.

I focused mostly on the people involved in science and technology but for more inspiration do go visit the TED2014 Fellows page. You can find out more about the Fellows program and find links to the application form here.

Earlier this year (2013), there was a great deal of excitement when the announcement was made that TED would be moving  from its longtime home (five years) in Long Beach, California to Vancouver, British Columbia for two years starting in 2014 from the Feb. 5, 2013 Vancouver Sun article by Jeff Lee,

For nearly three decades the conference — known for its motto of “Ideas Worth Spreading” and its popular TED Talks interviews — has called California home. That it was considering leaving the United States to come to Canada was, for Klassen [Greg Klassen, the senior vice-president of marketing for the Canadian Tourism Commission and Antonson [Rick Antonson, Tourism Vancouver CEO], stunning. This was the Holy Grail of conferences, so big in fact that it might even be viewed on the same level as the idea for the Vancouver 2010 Winter Olympics — whose birth, ironically, had taken place 15 years earlier around the same table.

“I turned to Katherine and said ‘I thought I was coming for Oprah. I never thought it was this big,’” Klassen recalled Monday [February 4, 2013].

To the uninitiated, bringing the 1,400-delegate TED conference to Vancouver may not seem like much. After all, this is an Olympic city that knows how to put on a show.

But then, TED is so rarefied, with its agenda of provocative leaders and speakers, that each of the attendees — many of them influencers and thought-changers in their own right — have to submit an essay on why they should be allowed to buy a $7,500 ticket.

The conference, one of the world’s most influential incubators of ideas about technology, entertainment and design (thus, TED), has become so popular that more than 1,000 of its speeches, which since 2006 are now indexed online, have received more than one billion views.

The main conference and a second global conference based in Edinburgh, Scotland, have featured everyone from presidents of countries and leading scientists to business leaders and social innovators.

In Frances Bula’s Feb. 4, 2013 article for the Globe and Mail, she described the response at Vancouver’s City Hall this way,

The Monday announcement caused a visible bubble of euphoria among city officials. “This is a game-changer for Vancouver. We’re known as a world-class tourism destination but this shows we’re breaking through in thought leadership,” Mayor Gregor Robertson said. “I’d like to explore how we can best leverage the opportunity to vault Vancouver into the spotlight and endear us to the leading thinkers who come here.”

While his [owner Chris Anderson] organization had been looking at various locales, Vancouver won their hearts. The city, where TED staff know several people already, was welcoming. (The organization, which has its main offices in New York, has had its conference-organizing staff based in Vancouver for a decade.)

As Bula notes in her article, there have been some criticisms of TED. Her Globe and Mail colleague, Gary Mason in his Feb. 7, 2013 article expounds further on that theme (Note: Links have been removed),

Until recently, TED – whose credo is Ideas Worth Spreading – enjoyed mostly fawning treatment from the popular press. Lately, however, the organization has been the recipient of some withering critiques. It has been skewered for lectures that are formulaic in design, that emphasize style over substance and that come across as little more than crass sales pitches for whatever book the presenter happens to be flogging.

Alex Pareene, writing in Salon.com, said the standard TED talk is modelled on a recipe popularized by author Malcolm Gladwell. Common tropes, he suggested, include oversimplified explanations of complex problems, idealistic solutions to said dilemmas, unconventional explanations for origins of identified vexing issues and “staggeringly obvious observations presented as mind-blowing new insights.”

The most devastating review of what TED has become was penned by a former conference presenter, Evgeny Morozov. Writing in The New Republic, he said TED was no longer a curator of ideas worth spreading but, instead, something quite menacing. “Today TED is an insatiable kingpin of international meme laundering – a place where ideas, regardless of their quality, go to seek celebrity, to live in the form of videos, tweets, and now e-books. In the world of TED … books become talks, talks become memes, memes become projects, projects become talks, talks become books – and so it goes ad infinitum in the sizzling Stakhanovite cycle of memetics, until any shade of depth or nuance disappears into the virtual void.”

All of this is not to say TED doesn’t have something to offer. Many of the lectures – including one by Sir Ken Robinson on how schools are killing creativity – are terrific.

Nathan Heller critiqued TED at length in a July 9, 2012 article for New Yorker Magazine (excerpted from the abstract; the full article is behind a paywall),

… Abroad, “TEDx” events run at a global rate of about five per day, in a hundred and thirty-three countries. [Describes the TED lecture of Lior Zoref, an Israeli Ph.D. student whose aim was to deliver a crowd-sourced talk, on the idea that a group of networked minds can shape a better product than an individual imagination.] TED’s closely governed editorial process begins with the concept: the conference’s “curators” feel out a speaker’s interests, looking for material that’s new and counterintuitive. … Critics tend to regard TED as a rogue force of idiocy, chasing ideas with a meat grinder while serious thinkers chew their leafy greens. … The TED talk is today a sentimental form. Once, searching for transport, people might have read Charles Dickens, rushed the dance floor, watched the Oscars, put on the Smiths. Now there is TED. The appeal of TED comes as much from its presentation as from its substance. Establishing intellectual credentials in order to break past them helps give TED a somewhat vaporous tone. … TED’s attendee list looks like something a Harvard development officer might hallucinate after huffing too much envelope glue. By most measures, TED shapes its style against the mores of academia. [emphasis mine] It’s a recourse for college-educated adults who want to close the gap between academic thought and the lives they live now.

Following up on the reference to academia, I found this June 18, 2013 Indiana University news release about academics and their TED talks (Note: Links have been removed),

Academics earn street cred with TED Talks but no points from peers, IU research shows

Though fewer in number, presentations by academics preferred by public

TED Talks, the most popular conference and events website in the world with over 1 billion informational videos viewed, provides academics with increased popular exposure but does nothing to boost citations of their work by peers, new research led by Indiana University [IU] has found.

In the comprehensive study of over 1,200 TED Talks videos and their presenters, lead author Cassidy R. Sugimoto, an assistant professor in IU Bloomington’s Department of Information and Library Science, and a team of researchers from Great Britain and Canada, also looked at the demographic make-up of TED Talks presenters — only 21 percent were academics, and of those only about one-quarter were women — and the relationship between a presenter’s credentials and a video’s popularity.

Data gathered from the TED website and from YouTube also found that male-authored videos on YouTube were more popular and more liked than those authored by women — possibly because research has shown that females are less likely to comment on YouTube than males — and that videos by academics were commented upon more often than those presented by non-academics. While YouTube videos by male presenters were more viewed than those by women, this was not true of the TED website.

“Overall, academic presenters were in the minority, yet their videos were preferred,” Sugimoto said. “This runs counter to past research that has argued that the public, because of a lack of literacy on the subject, has a negative perception of science and technology that has been fostered by the media.”

The new work instead finds positive associations with science and technology information and possibly, Sugimoto noted, some discerning characteristics in the public between presentations by academics and non-academics.

Co-authors with Sugimoto on “Scientists Popularizing Science: Characteristics and Impact of TED Talk Presenters,” were IU doctoral student Andrew Tsou; Mike Thelwall of University of Wolverhampton, United Kingdom; Vincent Lariviere and Benoit Macaluso of Universite de Montreal and the Universite du Quebec a Montreal; and Philippe Mongeon, Universite de Montreal. The new research appeared in PLoS ONE.

The work was funded by the Digging Into Data initiative, a multinational funding program to promote “big data” research. Teams must be composed of scholars from at least two countries and receive funding from one of a number of potential national scholars. The U.S. portion of this grant was funded by the National Science Foundation.

Here’s a link to and a citation for the published paper, which is open access,

Scientists Popularizing Science: Characteristics and Impact of TED Talk Presenters by Cassidy R. Sugimoto, Mike Thelwall, Vincent Larivière, Andrew Tsou, Philippe Mongeon, & Benoit Macaluso. Published: Apr 30, 2013  PLoS ONE 8(4): e62403. doi:10.1371/journal.pone.0062403

Say what you will about TED, it cannot be denied that it has captured attention and has influence. I think it’s a good sign that it’s being criticized and critiqued, one doesn’t bother with the unimportant and the irrelevant. For anyone who’s thinking of attending March 17-21, 2014 in Vancdouver, (as of 2013, you needed $7500US and you had to write an essay), here’s more from TED2014’s program overview (this is the organization’s 30th anniversary year),

4 exciting changes

First and foremost, we’re moving to a spectacular location: Vancouver, Canada, one of the world’s great cities, combining a thriving culture of innovation, with glorious nature. There’s a new convention center there in the harbor that takes our breath away. It’s across the street from three terrific hotels, with more options within a short walk, and offers majestic 360-degree views of water and mountains.

Second, we’re reducing the audience size. You heard that right. From 1,400 in Long Beach, we’ll reduce to just 1,200 attendees. Every successful conference has to find a balance between scale and intimacy, and we think this is the year to nudge back a little smaller, so that in-depth human connection will be easier.

Third, we’re inviting back to TED2014 some of the best TED speakers of all time. Not necessarily for the main stage … but to join us in the audience, and contribute to breakout groups, lunches and dinners. TED2014 will feel like a glorious reunion, and a wonderful opportunity to connect one on one with the people who’ve done so much to shape how we see the world.

Finally, we’re pulling in some of TED’s greatest design talents to help us create a new kind of theater space. The convention center includes a beautiful open area that is perfect for us to install a custom-designed-for-talk-theater we have long dreamed of — one whose sole goal is connect speaker with audience as powerfully as possible. Nothing quite like this currently exists.

The TED2014 experience includes:
  • Starting Monday at 6pm, the famous TED mainstage program full of 18-minute talks, plus music, comedy, dance, short talks, video and other surprises.
  • TED Fellows Talks, where you’ll hear about projects and visions of the next generation of world-changers.
  • TED University, where TEDsters share their own expertise, from “How to negotiate a term sheet” to “How to break a board with your bare hands.”
  • Evening events, art exhibits, tech demos and other immersive experiences
  • Caffeine-fueled conversation breaks between sessions
  • Spaces to watch TED in an informal setting — on couches, beds, beanbag chairs; while blogging, tweeting, eating, networking …
  • The TED Gift Bag
  • Online tools for connecting with other attendees, before and after the conference
  • TED Book Club mailings

Enjoy either in person or via the podcasts that will be posted. Finally, congratulations to the 2014TED Fellows.

Alberta’s (Canada) Ingenuity Lab and its nanotechnology dreams

I believe the Nov. 6, 2013 news release from Alberta’s Ingenuity Lab was meant to announce this new lab’s existence (why does Alberta need another nanotechnology-focused institution?),

Alberta’s first accelerator laboratory brings together some of nanotechnology’s leading players to make small science have a big impact in Alberta, by harnessing and commercializing emerging technologies, and simultaneously addressing some of the grand challenges faced by our province.

“We still have an incredible amount to learn from nature. This we know,” says Ingenuity Lab Director, Dr. Carlo Montemagno. “The opportunity in front of us is the potential to create a bio-enabled, globally-competitive and value-added industry while training the next generation of researchers and innovators in Alberta.”

With a research team of 25 strong and growing, Ingenuity Lab is focusing its research on the mining, energy, agriculture and health sectors, and is a $40 million provincial government led initiative working in partnership with the National Institute for Nanotechnology (NINT), Campus Alberta and industry.

Alberta already hosts the National Institute of Nanotechnology (which was and perhaps still is partially funded by the province of Alberta) and there’s ACAMP “(Alberta Centre for Advanced MNT Products) is a not for profit organization that provides specialized services to micro nano technology clients. Clients have access to world-class equipment, facilities …” Both the University of Alberta and the University of Calgary have any number of labs dedicated to nanotechnology research and then there’s nanoAlberta which now lives on as part of  Alberta Innovates where* it’s listed on their Programs and Services page. It seems to me they have a number of organizations devoted to nanotechnology research and/or commercialization in Alberta. By the way, Canada’s National Institute of Nanotechnology (NINT) can still be found on two different websites; there’s the NINT on the National Research Council of Canada website and there’s the NINT on the University of Alberta website.

While the lab’s Nov. 19, 2013 news release (h/t Nanowerk) explores the lab’s goals, it doesn’t really answer the question: why another one?,

Dr. Carlo Montemagno and a world-class team of researchers are working across disciplines to identify innovative solutions to some of the province’s most difficult issues, including optimal resource extraction while enhancing environmental stewardship of Alberta’s signature natural resources [oil sands].

“Nanotechnology will have a significant impact on Canada’s economic prosperity and global competitive advantage,” says Ingenuity Lab Director, Dr. Carlo Montemagno.  “This enhanced understanding of matter will provide the necessary underpinning for revolutionary discoveries across disciplines that will forever change the way we envisage the future.”

Ingenuity Lab is applying recent advances in targeted drug delivery and other areas to develop novel technologies that will enable the recovery of valuable materials, currently discarded as waste, from our industrial operations and the environment.

The Ingenuity research team is engineering new materials that have the capability to detect, extract and bind to rare earth and precious metals that exist in nature or synthetic materials. As this approach is refined, it will spawn a variety of applications like reclamation of trace amounts of valuable or harmful materials from soil, water and industrial process streams, including tailing ponds.

“Our molecular recognition techniques, what we call biomining, offer the ability to maximize the utility of our resources, establish a new path forward to restore damaged lands and water and to reaffirm Canada’s commitment to societal and economic prosperity,” says Dr. Montemagno. “The further we delve into the very makeup of the natural and inorganic components of our universe, the more opportunities we uncover. This radical shift away from conventional thinking means that we leverage research gains beyond their intended purpose. We achieve a multiplier effect that increases the capacity of nanotechnology to address the grand challenges facing modern industrial societies.”

I became a little curious about Dr. Montemagno and found this on the Ingenuity Lab’s About the Director page,

Dr. Carlo Montemagno

“The purpose of scientific study is to create new knowledge by working at the very edge where world-changing knowledge unfolds.” – C. Montemagno

Driven by the principles of excellence, honor and responsibility and an unwavering commitment to education as an engine of economic prosperity, Dr. Montemagno has become a world-renowned expert in nanotechnology and is responsible for creating groundbreaking innovations which solve complex challenges in the areas of informatics, agriculture, chemical refining, transportation, energy, and healthcare.

He was Founding Dean of the College of Engineering and Applied Sciences at University of Cincinnati; received a Bachelor of Science degree in Agriculture and Bio Engineering from Cornell University; a Master’s Degree  in Petroleum and Natural Gas Engineering from Penn State and a Ph.D. in Civil Engineering and Geological Sciences from Notre Dame.

“Research and education are critical to success because the transfer of knowledge creates economic prosperity.” — C. Montemagno

Dr. Montemagno has been recognized with prestigious awards including the Feynman Prize (for creating single molecule biological motors with nano-scale silicon devices); the Earth Award Grand Prize (for cell-free artificial photosynthesis with over 95% efficiency); the CNBC Business Top 10 Green Innovator award (for Aquaporin Membrane water purification and desalination technology); and named a Bill & Melinda Gates Grand Challenge Winner (for a pH sensing active microcapsule oral vaccine delivery system which increased vaccine stability and demonstrated rapid uptake in the lower GI tract.)

Despite my doubts, I wish the Ingenuity Lab folks good luck with their efforts.

*where’s changed to where, Feb. 3, 2014

A new science magazine edited and peer-reviewed by children: Frontiers for Young Minds

November 15, 2013 article by Alice Truong about Frontiers for Young Minds (for Fast Company), profiles a new journal meant to be read by children and edited and peer-reviewed by children. Let’s start with an excerpt from the Truong article as an introduction to the Frontiers for Young Minds journal (Note: Links have been removed),

Frontiers for Young Minds is made up of editors ages 8 to 18 who learn the ropes of peer review from working scientists. With 18 young minds and 38 adult authors and associate editors lending their expertise, the journal–an offshoot of the academic research network Frontiers …

With a mission to engage a budding generation of scientists, UC [University of California at] Berkeley professor Robert Knight created the kid-friendly version of Frontiers and serves as its editor-in-chief. The young editors review and approve submissions, which are written so kids can understand them–“clearly, concisely and with enthusiasm!” the guidelines suggest. Many of the scientists who provide guidance are academics, hailing from Harvard to Rio de Janeiro’s D’Or Institute for Research and Education. The pieces are peer reviewed by one of the young editors, but to protect their identities only their first names are published along with the authors’ names.

Great idea and bravo to all involved in the project! Here’s an excerpt from the Frontiers for Young Minds About webpage,

Areas in Development now include:

  • The Brain and Friends (social neuroscience)
  • The Brain and Fun (emotion)
  • The Brain and Magic (perception, sensation)
  • The Brain and Allowances (neuroeconomics)
  • The Brain and School (attention, decision making)
  • The Brain and Sports (motor control, action)
  • The Brain and Life (memory)
  • The Brain and Talking/Texting (language)
  • The Brain and Growing (neurodevelopment)
  • The Brain and Math (neural organization of math, computational neuroscience)
  • The Brain and Health (neurology, psychiatry)
  • The Brain and Robots (brain machine interface)
  • The Brain and Music (music!)
  • The Brain and Light (optogenetics)
  • The Brain and Gaming (Fun, Action, Learning)
  • The Brain and Reading
  • The Brain and Pain
  • The Brain and Tools (basis of brain measurements)
  • The Brain and History (the story of brain research)
  • The Brain and Drugs (drugs)
  • The Brain and Sleep

I believe the unofficial title for this online journal is Frontiers (in Neuroscience) for Young Minds. I guess they were trying to make the title less cumbersome which, unfortunately, results in a bit of confusion.

At any rate, there’s a quite a range of young minds at work as editors and reviewers, from the Editorial Team’s webpage,

Sacha
14 years old
Amsterdam, Netherlands

When I was just a few weeks old, we moved to Bennekom, a small town close to Arnhem (“a bridge too far”). I am now 14 and follow the bilingual stream in secondary school, receiving lessons in English and Dutch. I hope to do the International Bacquelaurate before I leave school. In my spare time, I like to play football and hang out with my mates. Doing this editing interested me for three reasons: I really wanted to understand more about my dad’s work; I like the idea of this journal that helps us understand what our parents do; and I also like the idea of being an editor!

Abby
11 years old
Israel

I currently live in Israel, but I lived in NYC and I loved it. I like wall climbing, dancing, watching TV, scuba diving, and I love learning new things about how our world works. Oh, I also love the Weird-but-True books. You should try reading them too.

Caleb
14 years old
Canada

I enjoy reading and thinking about life. I have a flair for the dramatic. Woe betide the contributor who falls under my editorial pen. I am in several theatrical productions and I like to go camping in the Canadian wilds. My comment on brains: I wish I had one.

Darius
10 years old
Lafayette, CA, USA

I am in fifth grade. In my free time I enjoy reading and computer programming. As a hobby, I make useful objects and experiment with devices. I am very interested in the environment and was one of the founders of my school’s green committee. I enjoy reading about science, particularly chemistry, biology, and neuroscience.

Marin
8 years old
Cambridge, MA, USA

3rd grader who plays the piano and loves to sing and dance. She participates in Science Club for Girls and she and her Mom will be performing in their second opera this year.

Eleanor
8 years old
Champaign, IL, USA

I like reading and drawing. My favorite colors are blue, silver, pink, and purple. My favorite food is creamed spinach. I like to go shopping with my Mom.

….

At age 8, I would have been less Marin and more Eleanor. I hated opera; my father made us listen every Sunday afternoon during the winters.

Here’s something from an article about brain-machine interfaces for the final excerpt from the website (from the articles webpage),

[downloaded from http://kids.frontiersin.org/articles/brain-machine_interfaces/7/]

[downloaded from http://kids.frontiersin.org/articles/brain-machine_interfaces/7/]

Brain-Machine Interfaces (BMI), or brain-computer interfaces (BCI), is an exciting multidisciplinary field that has grown tremendously during the last decade. In a nutshell, BMI is about transforming thought into action and sensation into perception. In a BMI system, neural signals recorded from the brain are fed into a decoding algorithm that translates these signals into motor output. This includes controlling a computer cursor, steering a wheelchair, or driving a robotic arm. A closed control loop is typically established by providing the subject with visual feedback of the prosthetic device. BMIs have tremendous potential to greatly improve the quality of life of millions of people suffering from spinal cord injury, stroke, amyotrophic lateral sclerosis, and other severely disabling conditions.6

I think this piece written by Jose M. Carmena and José del R. Millán and reviewed by Bhargavi, 13 years old, is a good beginner’s piece for any adults who might be interested, as well as,, the journal’s target audience. This illustration the scientists have provided is very helpful to anyone who, for whatever reason, isn’t that knowledgeable about this area of research,

Figure 1 - Your brain in action: the different components of a BMI include the recording system, the decoding algorithm, device to be controlled, and the feedback delivered to the user (modified from Heliot and Carmena, 2010).

Figure 1 – Your brain in action:
the different components of a BMI include the recording system, the decoding algorithm, device to be controlled, and the feedback delivered to the user (modified from Heliot and Carmena, 2010).

As for getting information about basic details, here’s some of what I unearthed. The parent organization, ‘Frontiers in’ is based in Switzerland and describes itself this way on its About page,

Frontiers is a community-oriented open-access academic publisher and research network.

Our grand vision is to build an Open Science platform that empowers researchers in their daily work and where everybody has equal opportunity to seek, share and generate knowledge.

Frontiers is at the forefront of building the ultimate Open Science platform. We are driving innovations and new technologies around peer-review, article and author impact metrics, social networking for researchers, and a whole ecosystem of open science tools. We are the first – and only – platform that combines open-access publishing with research networking, with the goal to increase the reach of publications and ultimately the impact of articles and their authors.

Frontiers was launched as a grassroots initiative in 2007 by scientists from the Swiss Federal Institute of Technology in Lausanne, Switzerland, out of the collective desire to improve the publishing options and provide better tools and services to researchers in the Internet age. Since then, Frontiers has become the fastest-growing open-access scholarly publisher, with a rapidly growing number of community-driven journals, more than 25,000 of high-impact researchers across a wide range of academic fields serving on the editorial boards and more than 4 million monthly page views.

As of a Feb. 27, 2013 news release, Frontiers has partnered with the Nature Publishing Group (NPG), Note: Links have been removed,

Emerging publisher Frontiers is joining Nature Publishing Group (NPG) in a strategic alliance to advance the global open science movement.

NPG, publisher of Nature, today announces a majority investment in the Swiss-based open access (OA) publisher Frontiers.

NPG and Frontiers will work together to empower researchers to change the way science is communicated, through open access publication and open science tools. Frontiers, led by CEO and neuroscientist Kamila Markram, will continue to operate with its own platform, brands, and policies.

Founded by scientists from École Polytechnique Fédérale de Lausanne (EPFL) in 2007, Frontiers is one of the fastest growing open access publishers, more than doubling articles published year on year. Frontiers now has a portfolio of open access journals in 14 fields of science and medicine, and published over 5,000 OA articles in 2012.

Working with NPG, the journal series “Frontiers in” will significantly expand in 2013-2014. Currently, sixty-three journals published by NPG offer open access options or are open access and NPG published over 2000 open access articles in 2012. Bilateral links between nature.com and frontiersin.org will ensure that open access papers are visible on both sites.

Frontiers and NPG will also be working together on innovations in open science tools, networking, and publication processes.

Frontiers is based at EPFL in Switzerland, and works out of Innovation Square, a technology park supporting science start-ups, and hosting R&D divisions of large companies such as Logitech & Nestlé.

As for this new venture, Frontiers for Young Minds, this appears to have been launched on Nov. 11, 2013. At least, that’s what I understand from this notice on Frontier’s Facebook page (Note: Links have been removed,

Frontiers
November 11 [2013?]
Great news for kids, parents, teachers and neuroscientists! We have just launched the first Frontiers for Young Minds!

Frontiers in #Neuroscience for Young Minds is an #openaccess scientific journal that involves young people in the review of articles.

This has the double benefit of bringing kids into the world of science and offering scientists a platform for reaching out to the broadest of all audiences.

Frontiers for Young Minds is science edited for kids, by kids. Learn more and spread the word! http://bit.ly/1dijipy #sfn13

I am glad to see this effort and I wish all the parties involved the best of luck.

World’s* smallest FM radio transmitter made out of graphene

I’m always amazed at how often nanotechnology is paired with radio. The latest ‘nanoradio’ innovation is from the University of Columbia School of Engineering. According to a November 18, 2013 news item on ScienceDaily,

 A team of Columbia Engineering researchers, led by Mechanical Engineering Professor James Hone and Electrical Engineering Professor Kenneth Shepard, has taken advantage of graphene’s special properties — its mechanical strength and electrical conduction — and created a nano-mechanical system that can create FM signals, in effect the world’s smallest FM radio transmitter.

One of my first ‘nanorado’ stories (in 2007 and predating the existence of this blog) focused on carbon nanotubes and a Zettl Group (Alex Zettl) project at the University of California at Berkeley (from the Zettl Group’s Nanotube Radio: Supplementary materials webpage),

We have constructed a fully functional, fully integrated radio receiver, orders-of-magnitude smaller than any previous radio, from a single carbon nanotube. The single nanotube serves, at once, as all major components of a radio: antenna, tuner, amplifier, and demodulator. Moreover, the antenna and tuner are implemented in a radically different manner than traditional radios, receiving signals via high frequency mechanical vibrations of the nanotube rather than through traditional electrical means. We have already used the nanotube radio to receive and play music from FM radio transmissions such as Layla by Eric Clapton (Derek and the Dominos) and the Beach Boy’s Good Vibrations. The nanotube radio’s extremely small size could enable radical new applications such as radio controlled devices small enough to exist in the human bloodstream, or simply smaller, cheaper, and more efficient wireless devices such as cellular phones.

The group features four songs transmitted via their carbon nanotube radio (from the ‘supplementary materials’ webpage),

A high resolution transmission electron microscope allows us to observe the nanotube radio in action. We have recorded four videos from the electron microscope of the nanotube radio playing four different songs. At the beginning of each video, the nanotube radio is tuned to a different frequency than that of the transmitted radio signal. Thus, the nanotube does not vibrate, and only static noise can be heard. As the radio is brought into tune with the transmitted signal, the nanotube begins to vibrate, which blurs its image in the video, and at the same time, the music becomes audible. The four songs are Good Vibrations by the Beach Boys, Largo from the opera Xerxes by Handel (this was the first song ever transmitted using radio), Layla by Eric Clapton (Derek & the Dominos), and the Main Title from Star Wars by John Williams.

Good Vibrations (Quicktime, 8.06 MB)
Layla (Quicktime, 6.13 MB)
Largo (Quicktime, 8.73 MB)
Star Wars (Quicktime, 8.68 MB)

‘Layla’ is quite scrtachy and barely audible but it is there, if you care to listen to this 2007 carbon nanotube radio project. Now in 2013 we have a graphene radio receiver and this graphene radio project is intended to achieve some of the goals as the carbon nanotube radio project,. From the Nov. 17, 2013 University of Columbia news release on newswise and also on EurekAlert),

“This work is significant in that it demonstrates an application of graphene that cannot be achieved using conventional materials,” Hone says. “And it’s an important first step in advancing wireless signal processing and designing ultrathin, efficient cell phones. Our devices are much smaller than any other sources of radio signals, and can be put on the same chip that’s used for data processing.”

Graphene, a single atomic layer of carbon, is the strongest material known to man, and also has electrical properties superior to the silicon used to make the chips found in modern electronics. The combination of these properties makes graphene an ideal material for nanoelectromechanical systems (NEMS), which are scaled-down versions of the microelectromechanical systems (MEMS) used widely for sensing of vibration and acceleration. For example, Hone explains, MEMS sensors figure out how your smartphone or tablet is tilted to rotate the screen.

In this new study, the team took advantage of graphene’s mechanical ‘stretchability’ to tune the output frequency of their custom oscillator, creating a nanomechanical version of an electronic component known as a voltage controlled oscillator (VCO). With a VCO, explains Hone, it is easy to generate a frequency-modulated (FM) signal, exactly what is used for FM radio broadcasting. The team built a graphene NEMS whose frequency was about 100 megahertz, which lies right in the middle of the FM radio band (87.7 to 108 MHz). They used low-frequency musical signals (both pure tones and songs from an iPhone) to modulate the 100 MHz carrier signal from the graphene, and then retrieved the musical signals again using an ordinary FM radio receiver.

“This device is by far the smallest system that can create such FM signals,” says Hone.

While graphene NEMS will not be used to replace conventional radio transmitters, they have many applications in wireless signal processing. Explains Shepard, “Due to the continuous shrinking of electrical circuits known as ‘Moore’s Law’, today’s cell phones have more computing power than systems that used to occupy entire rooms. However, some types of devices, particularly those involved in creating and processing radio-frequency signals, are much harder to miniaturize. These ‘off-chip’ components take up a lot of space and electrical power. In addition, most of these components cannot be easily tuned in frequency, requiring multiple copies to cover the range of frequencies used for wireless communication.”

Unfortunately I haven’t seen any audio files for this ‘graphene radio’ but here’s a link to and a citation for the 2013 paper ,

Graphene mechanical oscillators with tunable frequency by Changyao Chen, Sunwoo Lee, Vikram V. Deshpande, Gwan-Hyoung Lee, Michael Lekas, Kenneth Shepard, & James Hone. Nature Nanotechnology (2013) doi:10.1038/nnano.2013.232 Published online 17 November 2013

The paper is behind a paywall.

* ‘Wolrd’s’ in headline corrected to ‘World’s’ on July 29, 2015.