Most people don’t realize how much energy computing, streaming video, and other technologies consume and AI (artificial intelligence) consumes a lot. (For more about work being done in this area, there’s my October 13, 2023 posting about an upcoming ArtSci Salon event in Toronto featuring Laura U. Marks’s recent work ‘Streaming Carbon Footprint’ and my October 16, 2023 posting about how much water is used for AI.)
Nanoelectronic device performs real-time AI classification without relying on the cloud
– AI is so energy hungry that most data analysis must be performed in the cloud – New energy-efficient device enables AI tasks to be performed within wearables – This allows real-time analysis and diagnostics for faster medical interventions – Researchers tested the device by classifying 10,000 electrocardiogram samples – The device successfully identified six types of heart beats with 95% accuracy
Northwestern University engineers have developed a new nanoelectronic device that can perform accurate machine-learning classification tasks in the most energy-efficient manner yet. Using 100-fold less energy than current technologies, the device can crunch large amounts of data and perform artificial intelligence (AI) tasks in real time without beaming data to the cloud for analysis.
With its tiny footprint, ultra-low power consumption and lack of lag time to receive analyses, the device is ideal for direct incorporation into wearable electronics (like smart watches and fitness trackers) for real-time data processing and near-instant diagnostics.
To test the concept, engineers used the device to classify large amounts of information from publicly available electrocardiogram (ECG) datasets. Not only could the device efficiently and correctly identify an irregular heartbeat, it also was able to determine the arrhythmia subtype from among six different categories with near 95% accuracy.
The research was published today (Oct. 12 [2023]) in the journal Nature Electronics.
“Today, most sensors collect data and then send it to the cloud, where the analysis occurs on energy-hungry servers before the results are finally sent back to the user,” said Northwestern’s Mark C. Hersam, the study’s senior author. “This approach is incredibly expensive, consumes significant energy and adds a time delay. Our device is so energy efficient that it can be deployed directly in wearable electronics for real-time detection and data processing, enabling more rapid intervention for health emergencies.”
A nanotechnology expert, Hersam is Walter P. Murphy Professor of Materials Science and Engineering at Northwestern’s McCormick School of Engineering. He also is chair of the Department of Materials Science and Engineering, director of the Materials Research Science and Engineering Center and member of the International Institute of Nanotechnology. Hersam co-led the research with Han Wang, a professor at the University of Southern California, and Vinod Sangwan, a research assistant professor at Northwestern.
Before machine-learning tools can analyze new data, these tools must first accurately and reliably sort training data into various categories. For example, if a tool is sorting photos by color, then it needs to recognize which photos are red, yellow or blue in order to accurately classify them. An easy chore for a human, yes, but a complicated — and energy-hungry — job for a machine.
For current silicon-based technologies to categorize data from large sets like ECGs, it takes more than 100 transistors — each requiring its own energy to run. But Northwestern’s nanoelectronic device can perform the same machine-learning classification with just two devices. By reducing the number of devices, the researchers drastically reduced power consumption and developed a much smaller device that can be integrated into a standard wearable gadget.
The secret behind the novel device is its unprecedented tunability, which arises from a mix of materials. While traditional technologies use silicon, the researchers constructed the miniaturized transistors from two-dimensional molybdenum disulfide and one-dimensional carbon nanotubes. So instead of needing many silicon transistors — one for each step of data processing — the reconfigurable transistors are dynamic enough to switch among various steps.
“The integration of two disparate materials into one device allows us to strongly modulate the current flow with applied voltages, enabling dynamic reconfigurability,” Hersam said. “Having a high degree of tunability in a single device allows us to perform sophisticated classification algorithms with a small footprint and low energy consumption.”
To test the device, the researchers looked to publicly available medical datasets. They first trained the device to interpret data from ECGs, a task that typically requires significant time from trained health care workers. Then, they asked the device to classify six types of heart beats: normal, atrial premature beat, premature ventricular contraction, paced beat, left bundle branch block beat and right bundle branch block beat.
The nanoelectronic device was able to identify accurately each arrhythmia type out of 10,000 ECG samples. By bypassing the need to send data to the cloud, the device not only saves critical time for a patient but also protects privacy.
“Every time data are passed around, it increases the likelihood of the data being stolen,” Hersam said. “If personal health data is processed locally — such as on your wrist in your watch — that presents a much lower security risk. In this manner, our device improves privacy and reduces the risk of a breach.”
Hersam imagines that, eventually, these nanoelectronic devices could be incorporated into everyday wearables, personalized to each user’s health profile for real-time applications. They would enable people to make the most of the data they already collect without sapping power.
“Artificial intelligence tools are consuming an increasing fraction of the power grid,” Hersam said. “It is an unsustainable path if we continue relying on conventional computer hardware.”
After seeing the description for Laura U. Marks’s recent work ‘Streaming Carbon Footprint’ (in my October 13, 2023 posting about upcoming ArtSci Salon events in Toronto), where she focuses on the environmental impact of streaming media and digital art, I was reminded of some September 2023 news.
A September 9, 2023 news item (an Associated Press article by Matt O’Brien and Hannah Fingerhut) on phys.org and also published September 12, 2023 on the Iowa Public Radio website, describe an unexpected cost for building ChatGPT and other AI agents, Note: Links have been removed,
The cost of building an artificial intelligence product like ChatGPT can be hard to measure.
But one thing Microsoft-backed OpenAI needed for its technology was plenty of water [emphases mine], pulled from the watershed of the Raccoon and Des Moines rivers in central Iowa to cool a powerful supercomputer as it helped teach its AI systems how to mimic human writing.
As they race to capitalize on a craze for generative AI, leading tech developers including Microsoft, OpenAI and Google have acknowledged that growing demand for their AI tools carries hefty costs, from expensive semiconductors to an increase in water consumption.
But they’re often secretive about the specifics. Few people in Iowa knew about its status as a birthplace of OpenAI’s most advanced large language model, GPT-4, before a top Microsoft executive said in a speech it “was literally made next to cornfields west of Des Moines.”
…
In its latest environmental report, Microsoft disclosed that its global water consumption spiked 34% from 2021 to 2022 (to nearly 1.7 billion gallons , or more than 2,500 Olympic-sized swimming pools), a sharp increase compared to previous years that outside researchers tie to its AI research. [emphases mine]
“It’s fair to say the majority of the growth is due to AI,” including “its heavy investment in generative AI and partnership with OpenAI,” said Shaolei Ren, [emphasis mine] a researcher at the University of California, Riverside who has been trying to calculate the environmental impact of generative AI products such as ChatGPT.
…
If you have the time, do read the O’Brien and Fingerhut article in it entirety. (Later in this post, I have a citation for and a link to a paper by Ren.)
Jason Clayworth’s September 18, 2023 article for AXIOS describes the issue from the Iowan perspective, Note: Links have been removed,
Future data center projects in West Des Moines will only be considered if Microsoft can implement technology that can “significantly reduce peak water usage,” the Associated Press reports.
Why it matters: Microsoft’s five WDM data centers — the “epicenter for advancing AI” — represent more than $5 billion in investments in the last 15 years.
Yes, but: They consumed as much as 11.5 million gallons of water a month for cooling, or about 6% of WDM’s total usage during peak summer usage during the last two years, according to information from West Des Moines Water Works.
…
This information becomes more intriguing (and disturbing) after reading a February 10, 2023 article for the World Economic Forum titled ‘This is why we can’t dismiss water scarcity in the US‘ by James Rees and/or an August 11, 2020 article ‘Why is America running out of water?‘ by Jon Heggie published by the National Geographic, which is a piece of paid content. Note: Despite the fact that it’s sponsored by Finish Dish Detergent, the research in Heggie’s article looks solid.
From Heggie’s article, Note: Links have been removed,
In March 2019, storm clouds rolled across Oklahoma; rain swept down the gutters of New York; hail pummeled northern Florida; floodwaters forced evacuations in Missouri; and a blizzard brought travel to a stop in South Dakota. Across much of America, it can be easy to assume that we have more than enough water. But that same a month, as storms battered the country, a government-backed report issued a stark warning: America is running out of water.
…
As the U.S. water supply decreases, demand is set to increase. On average, each American uses 80 to 100 gallons of water every day, with the nation’s estimated total daily usage topping 345 billion gallons—enough to sink the state of Rhode Island under a foot of water. By 2100 the U.S. population will have increased by nearly 200 million, with a total population of some 514 million people. Given that we use water for everything, the simple math is that more people mean more water stress across the country.
And we are already tapping into our reserves. Aquifers, porous rocks and sediment that store vast volumes of water underground, are being drained. Nearly 165 million Americans rely on groundwater for drinking water, farmers use it for irrigation―37 percent of our total water usage is for agriculture—and industry needs it for manufacturing. Groundwater is being pumped faster than it can be naturally replenished. The Central Valley Aquifer in California underlies one of the nation’s most agriculturally productive regions, but it is in drastic decline and has lost about ten cubic miles of water in just four years.
Decreasing supply and increasing demand are creating a perfect water storm, the effects of which are already being felt. The Colorado River carved its way 1,450 miles from the Rockies to the Gulf of California for millions of years, but now no longer reaches the sea. In 2018, parts of the Rio Grande recorded their lowest water levels ever; Arizona essentially lives under permanent drought conditions; and in South Florida’s freshwater aquifers are increasingly susceptible to salt water intrusion due to over-extraction.
…
The focus is on individual use of water and Heggie ends his article by suggesting we use less,
… And every American can save more water at home in multiple ways, from taking shorter showers to not rinsing dishes under a running faucet before loading them into a dishwasher, a practice that wastes around 20 gallons of water for each load. …
As an advertising pitch goes, this is fairly subtle as there’s no branding in the article itself and it is almost wholly informational.
Attempts to stave off water shortages as noted in Heggie’s and other articles include groundwater pumping both for individual use and industrial use. This practice has had an unexpected impact according to a June 16, 2023 article by Warren Cornwall for Science (magazine),
While spinning on its axis, Earth wobbles like an off-kilter top. Sloshing molten iron in Earth’s core, melting ice, ocean currents, and even hurricanes can all cause the poles to wander. Now, scientists have found that a significant amount of the polar drift results from human activity: pumping groundwater for drinking and irrigation.
“The very way the planet wobbles is impacted by our activities,” says Surendra Adhikari, a geophysicist at NASA’s Jet Propulsion Laboratory and an expert on Earth’s rotation who was not involved in the study. “It is, in a way, mind boggling.”
…
Clark R. Wilson, a geophysicist at the University of Texas at Austin, and his colleagues thought the removal of tens of gigatons of groundwater each year might affect the drift. But they knew it could not be the only factor. “There’s a lot of pieces that go into the final budget for causing polar drift,” Wilson says.
The scientists built a model of the polar wander, accounting for factors such as reservoirs filling because of new dams and ice sheets melting, to see how well they explained the polar movements observed between 1993 and 2010. During that time, satellite measurements were precise enough to detect a shift in the poles as small as a few millimeters.
Dams and ice changes were not enough to match the observed polar motion. But when the researchers also put in 2150 gigatons of groundwater that hydrologic models estimate were pumped between 1993 and 2010, the predicted polar motion aligned much more closely with observations. Wilson and his colleagues conclude that the redistribution of that water weight to the world’s oceans has caused Earth’s poles to shift nearly 80 centimeters during that time. In fact, groundwater removal appears to have played a bigger role in that period than the release of meltwater from ice in either Greenland or Antarctica, the scientists reported Thursday [June 15, 2023] in Geophysical Research Letters.
…
The new paper helps confirm that groundwater depletion added approximately 6 millimeters to global sea level rise between 1993 and 2010. “I was very happy” that this new method matched other estimates, Seo [Ki-Weon Seo geophysicist at Seoul National University and the study’s lead author] says. Because detailed astronomical measurements of the polar axis location go back to the end of the 19th century, polar drift could enable Seo to trace the human impact on the planet’s water over the past century.
Two papers: environmental impact from AI and groundwater pumping wobbles poles
I have two links and citations for Ren’s paper on AI and its environmental impact,
Towards Environmentally Equitable AI via Geographical Load Balancing by Pengfei Li, Jianyi Yang, Adam Wierman, Shaolei Ren. Subjects: Artificial Intelligence (cs.AI); Computers and Society (cs.CY) Cite as: arXiv:2307.05494 [cs.AI] (or arXiv:2307.05494v1 [cs.AI] for this version) DOI: https://doi.org/10.48550/arXiv.2307.05494 Submitted June 20, 2023
Join us to welcome Cerpina and Stenslie as they introduce us to their book and discuss the future cuisine of humanity. To sustain the soon-to-be 9 billion global population we cannot count on Mother Earth’s resources anymore. The project explores innovative and speculative ideas about new foods in the field of arts, design, science & technology, rethinking eating traditions and food taboos, and proposing new recipes for survival in times of ecological catastrophes.
To match the topic of their talk, attendees will be presented with “anthropocene snacks” and will be encouraged to discuss food alternatives and new networks of solidarity to fight food deserts, waste, and unsustainable consumption.
This is a Hybrid event: our guests will join us virtually on zoom. Join us in person at Glendon Campus, rm YH190 (the studio next to the Glendon Theatre) for a more intimate community experience and some anthropocene snacks. If you wish to join us on Zoom, please
This event is part of a series on Emergent Practices in Communication, featuring explorations on interspecies communication and digital networks; land-based justice and collective care. The full program can be found here
This initiative is supported by York University’s Teaching Commons Academic Innovation Fund
Zane Cerpina is a multicultural and interdisciplinary female author, curator, artist, and designer working with the complexity of socio-political and environmental issues in contemporary society and in the age of the Anthropocene. Cerpina earned her master’s degree in design from AHO – The Oslo School of Architecture and Design and a bachelor’s degree in Art and Technology from Aalborg University. She resides in Oslo and is a project manager/curator at TEKS (Trondheim Electronic Arts Centre). She is also a co-founder and editor of EE: Experimental Emerging Art Journal. From 2015 to 2019, Cerpina was a creative manager and editor at PNEK (Production Network for Electronic Art, Norway).
Stahl Stenslie works as an artist, curator and researcher specializing in experimental media art and interaction experiences. His aesthetic focus is on art and artistic expressions that challenge ordinary ways of perceiving the world. Through his practice he asks the questions we tend to avoid – or where the answers lie in the shadows of existence. Keywords of his practice are somaesthetics, unstable media, transgression and numinousness. The technological focus in his works is on the art of the recently possible – such as i) panhaptic communication on Smartphones, ii) somatic and immersive soundspaces, and iii) design of functional and lethal artguns, 3D printed in low-cost plastic material.He has a PhD on Touch and Technologies from The School of Architecture and Design, Oslo, Norway. Currently he heads the R&D department at Arts for Young Audiences Norway.
If you’re interested in the book, there’s the anthropocenecookbook.com, which has more about the book and purchase information,
The Anthropocene Cookbook is by far the most comprehensive collection of ideas about future food from the perspective of art, design, and science. It is a thought-provoking book about art, food, and eating in the Anthropocene –The Age of Man– and the age of catastrophes.
Published by The MIT Press [MIT = Massachusetts Institute of Technology] | mitpress.mit.edu
Supported by TEKS Trondheim Electronic Arts Centre | www.teks.no
*Date changed* Streaming Carbon Footprint on October 27, 2023
Keep scrolling down to Date & location changed for Streaming Carbon Footprint subhead.
From the Toronto ArtSci Salon October 5, 2023 announcement,
Oct 27, [2023] 5:00-7:00 PM [ET] Streaming Carbon Footprint
with Laura U. Marks and David Rokeby – Room 230 The Fields Institute for Research in Mathematical Sciences 222 College Street, Toronto
We are thrilled to announce this dialogue between media Theorist Laura U. Marks and Media Artist David Rokeby. Together, they will discuss a well known elephant in the room of media and digital technologies: their carbon footprint. As social media and streaming media usage increases exponentially, what can be done to mitigate their impact? are there alternatives?
This is a live event: our guests will join us in person.
if you wish to join us on Zoom instead, a link will be circulated on our website and on social media a few days before the event. The event will be recorded
Laura U. Marks works on media art and philosophy with an intercultural focus, and on small-footprint media. She programs experimental media for venues around the world. As Grant Strate University Professor, she teaches in the School for the Contemporary Arts at Simon Fraser University in Vancouver, Canada. Her upcoming book The Fold: From Your Body to the Cosmos will be published I March 2024 by Duke University Press.
David Rokeby is an installation artist based in Toronto, Canada. He has been creating and exhibiting since 1982. For the first part of his career he focussed on interactive pieces that directly engage the human body, or that involve artificial perception systems. In the last decade, his practice has expanded to included video, kinetic and static sculpture. His work has been performed / exhibited in shows across Canada, the United States, Europe and Asia.
Awards include the first BAFTA (British Academy of Film and Television Arts) award for Interactive Art in 2000, a 2002 Governor General’s award in Visual and Media Arts and the Prix Ars Electronica Golden Nica for Interactive Art 2002. He was awarded the first Petro-Canada Award for Media Arts in 1988, the Prix Ars Electronica Award of Distinction for Interactive Art (Austria) in 1991 and 1997.
I haven’t been able to dig up any information about registration but it will be added here should I stumble across any in the next few weeks. I did, however, find more information about Marks’s work and a festival in Vancouver (Canada).
Fourth Annual Small File Media Festival (October 20 -21, 2023) and the Streaming Carbon Footprint
When was the last time you watched a DVD? If you’re like most people, your DVD collection has been gathering dust as you stream movies and TV from a variety of on-demand services. But have you ever considered the impact of streaming video on the environment?
School for the Contemporary Arts professor Laura Marks and engineering professor Stephen Makonin, with engineering student Alejandro Rodriguez-Silva and media scholar Radek Przedpełski, worked together for over a year to investigate the carbon footprint of streaming media supported by a grant from the Social Sciences and Humanities Research Council of Canada.
“Stephen and Alejandro were there to give us a reality check and to increase our engineering literacy, and Radek and I brought the critical reading to it,” says Marks. “It was really a beautiful meeting of critical media studies and engineering.”
After combing through studies on Information and Communication Technologies (ICT) and making their own calculations, they confirmed that streaming media (including video on demand, YouTube, video embedded in social media and websites, video conferences, video calls and games) is responsible for more than one per cent of greenhouse gas emissions worldwide. And this number is only projected to rise as video conferencing and streaming proliferate.
“One per cent doesn’t sound like a lot, but it’s significant if you think that the airline industry is estimated to be 1.9 per cent,” says Marks. “ICT’s carbon footprint is growing fast, and I’m concerned that because we’re all turning our energy to other obvious carbon polluters, like fossil fuels, cars, the airline industry, people are not going to pay attention to this silent, invisible carbon polluter.”
One thing that Marks found surprising during their research is how politicized this topic is.
Their full report includes a section detailing the International Energy Association’s attack on French think tank The Shift Project after they published a report on streaming media’s carbon footprint in 2019. They found that some ICT engineers state that the carbon footprint of streaming is not a concern because data centres and networks are very efficient, while others say the fast-rising footprint is a serious problem that needs to be addressed. Their report includes comparisons of the divergent figures in engineering studies in order to get a better understanding of the scope of this problem.
The No. 1 thing Marks and Makonin recommend to reduce streaming’s carbon footprint is to ensure that our electricity comes from renewable sources. At an individual level, they offer a list of recommendations to reduce energy consumption and demand for new ICT infrastructure including: stream less, watch physical media including DVDs, decrease video resolution, use audio-only mode when possible, and keep your devices longer—since production of devices is very carbon-intensive.
Promoting small files and low resolution, Marks founded the Small File Media Festival [link leads to 2023 programme], which will present its second annual program [2021] of 5-megabyte films Aug. 10 – 20. As the organizers say, movies don’t have to be big to be binge-worthy.
And now for 2023, here’s a video promoting the upcoming fourth annual festival,
The Streaming Carbon Footprint webpage on the SFU website includes information about the final report and the latest Small File Media Festival. Although I found the Small File Media Festival website also included a link for purchasing tickets,
The Small File Media Festival returns for its fourth iteration! We are delighted to partner with The Cinematheque to present over sixty jewel-like works from across the globe. These movies are small in file size, but huge in impact: by embracing the aesthetics of compression and low resolution (glitchiness, noise, pixelation), they lay the groundwork for a new experimental film movement in the digital age. This year, six lovingly curated programs traverse brooding pixelated landscapes, textural paradises, and crystalline infinities.
Join us Friday, October 20 [2023] for the opening-night program followed by a drinks reception in the lobby and a dance party in the cinema, featuring music by Vancouver electronic artist SAN. We’ll announce the winner of the coveted Small-File Golden Mini Bear during Saturday’s [October 21, 2023] award ceremony! As always, the festival will stream online at smallfile.ca after the live events.
We’re most grateful to our future-forward friends at the Social Sciences and Humanities Research Council of Canada, Canada Council for the Arts, and SFU Contemporary Arts. Thanks to VIVO Media Arts, Cairo Video Festival, and The Hmm for generous distribution and exhibition awards, and to UKRAïNATV, a partner in small-file activism.
Cosmically healthy, community-building, and punk AF, small-file ecomedia will heal the world, one pixel at a time.
From an October 12, 2023 Canadian Science Policy Centre (CSPC) announcement received via email,
Science Meets Parliament 2024 Application Deadline is Nov 9th!
You still have some time, the deadline to submit your applications for Science Meets Parliament 2024, is Thursday, Nov 9th [2023]! To apply, click here..
Science Meets Parliament (SMP) is a program that works to strengthen the connections between the science and policy communities. This program is open to Tier II Canada Research Chairs, Indigenous Principal Investigators, and Banting Postdoctoral Fellows.
Two events: October 13, 2023 and October 24, 2023
From an October 12, 2023 Canadian Science Policy Centre (CSPC) announcement,
Upcoming Virtual Panel [Canada-Brazil Cooperation and Collaboration in STI [Science, Technology, and Innovation]]
This virtual panel aims to discuss the ongoing Science, Technology, and Innovation (STI) cooperation between Brazil and Canada, along with the potential for furthering this relationship. The focus will encompass strategic areas of contact, ongoing projects, and scholarship opportunities. It is pertinent to reflect on the science diplomacy efforts of each country and their reciprocal influence. Additionally, the panel aims to explore how Canada engages with developing countries in terms of STI.
Please note the panel date has been changed to October 13th at 12pm EST. Click the button below to register for the upcoming virtual panel! Register Here
An event to mark a CSPC research report,
Report Launch on The Hill! CSPC Survey of Parlimentarians!
CSPC has organized a panel discussion on Oct 24th [2023] at 8 AM [EST] on Parliament Hill to launch the results of the project: “Survey of Parliamentarians on the Impact of the Pandemic on the Use of Science in Policy Making”.
This project was conducted by the CSPC’s Evaluation and Reports Committee, which began the dissemination of the survey to parliamentarians in 2021. The objective was to gather information on the impact of the pandemic on the use of science in policy-making. Survey responses were analyzed and a full report is going to be presented and publicized.
More information about the survey and the Final Report on the Survey of Parliamentarians can be found HERE.
To attend this in-person event, please click the button below. Register Here
Funky or not? Final Report on the Survey of Parliamentarians
[downloaded from https://sciencepolicy.ca/survey-of-parliamentarians/]
Wouldn’t it have been surprising if the survey results had shown that parliamentarians weren’t interested in getting science information when developing science policies? Especially surprising given that the survey was developed, conducted, and written up by the Canadian Science Policy Centre.
While there is a lot of interesting material, I really wish the authors had addressed the self-serving nature of this survey in their report. To their credit they do acknowledge some of the shortcomings, from the report (PDF), here’s the conclusion, Note: All emphases are mine,
There was near unanimous agreement by parliamentarians that there is a need for scientific knowledge in an accessible and policy-ready format. Building upon that, and taking into account the difficulties that parliamentarians identified in acquiring scientific knowledge to support policy- making, there were two main facilitators suggested by participants that may improve timely and understandable scientific knowledge in parliamentarian work. Firstly, the provision of scientific knowledge in a policy-ready format through a non-partisan science advice mechanism such as a non-partisan science advisor for the House of Commons and Senate. Secondly, research summaries in an accessible format and/or briefing of hot scientific topics provided by experts. As parliamentarians revealed in this survey, there is a clear desire to use scientific knowledge more frequently as a result of the COVID-19 pandemic. Therefore, the scientific community has an opportunity to support parliamentarians in this regard through mechanisms such as those indicated here.
Notwithstanding, the findings above come with some limitations within this study. First, the committee acknowledges that due to the small sample size of survey participants – particularly for MPs – the results presented in this report may not be representative of the parliamentarians of the 43rd Canadian Parliament. The committee also acknowledges that this limitation is further compounded by incomplete demographic representation. Although the committee made great efforts to achieve a survey demographic across gender, party affiliation, geographical location, and language that was representative of the 43rd Canadian Parliament, there were certain demographics that were ultimately under-represented. For these reasons, trends highlighted in this report and comparisons between MPs and senators should be interpreted with these limitations in mind. Finally, the committee acknowledged the possibility that the data presented in this report may be biased towards more positive perceptions of scientific knowledge, since this survey was more likely to have been completed by parliamentarians who have an interest in science. Even with these limitations, this study provides a critical step forward in understanding parliamentarians’ needs regarding acquisition of scientific knowledge in their work and proposing possible mechanisms to support these needs.
In conclusion, the current report reveals that parliamentarians’ inclination to use science in policy-making has increased in light of the COVID-19 pandemic. Moreover, parliamentarians are more aware than ever of the necessity for accurate and accessible scientific knowledge in their work. There are clear challenges facing the use of scientific knowledge in policy-making, namely misinformation and disinformation, but participants highlighted different key proposed mechanisms that can better integrate science and research into the framework of public policy. [p. 34]
Self-selection (“more likely to have been completed by parliamentarians who have an interest in science”) is always a problem. As for geographical representation, no one from BC, Saskatchewan, the Yukon, Nunavut, or the Northwest Territories responded.
Intriguingly, there were 18 Senators and 8 MP (members of Parliament) for a total of 26 respondents (see pp. 15-16 in the report [PDF] for more about the demographics).
I wish they had asked how long someone had served in Parliament. (Yes, a bit tricky when an MP is concerned but perhaps asking for a combined total would solve the problem.)
While I was concerned about the focus on COVID-19 and the generic sounding references to ‘scientific knowledge’, my concerns were somewhat appeased with this, from the report (PDF),
Need for different types of scientific knowledge
The committee found that across all participants, there was an increased need for all listed types of scientific knowledge by the majority of participants. One parliamentarian elaborated on this, highlighting that several Bills have touched on these areas over the course of the COVID-19 pandemic and that in their research work, parliamentarians have had to refer to these areas of scientific knowledge regularly.
Unsurprisingly, the type of scientific knowledge reported to have the largest increase in need was health sciences (85%). Notably, 4% or less of participants indicated a lesser need for all types of scientific knowledge, with health science, social science and humanities, and natural sciences and engineering seeing no decline in need by participants. Both MP and senator participants reported a greater need for research and evidence in health sciences (e.g., public health, vaccine research , cancer treatment etc.), social sciences and humanities (e.g., psychology, sociology, law, ethics), and environmental sciences (e.g., climate, environment, earth studies) as a result of the COVID-19 pandemic. Particularly, one parliamentarian reflected that there is an increased need among policy- makers to be objective and listen to scientists, as well as scientific data and evidence in areas such as public health and climate change. However, the relative increase in need for each subject between groups was different. For instance, senator participants reported the largest increase in need for health sciences (89%), followed by environmental science (78%) and social sciences and humanities (73%); whereas MP participants reported the largest increase in need for social sciences and humanities (88%), followed by health sciences (75%) and environmental science (63%).
…
Economics, Indigenous Knowledge, and natural sciences and engineering (e.g., biology, chemistry, physics, mathematics, engineering) had smaller increases in need for both MPs and senators. For both groups, natural sciences and engineering saw 50% of participants indicate an increase in need. In the case of economics and Indigenous Knowledge, senators noted a larger increase in need for these fields compared to MPs. In particular, in the case of Indigenous Knowledge only 37% of MPs reported an increased need for this type of scientific knowledge compared to 61% of senators.
Finally, one parliamentarian noted that climate change and Indigenous issues have gained a greater prominence since the pandemic, but not necessarily as a result of it. Therefore, in addition to putting these responses in the context of the COVID-19 pandemic, these responses should also be considered in the context of other global and Canadian issues that arose over the course of this survey (Question 4, Annex A [Cannot find any annexes]). [pp. 21-22]
Interesting to read (although I seem to have stumbled onto the report early as it’s no longer available as of October 13, 2023 at 10:10 am PT) from the “Survey of Parliamentarians: Impact of the COVID-19 pandemic on the use of science in policymaking” CSPC webpage.
As for funky, I think you need to be really clear that you’re aware your report can readily be seen as self-serving and note what steps you’ve taken to address the issue.
it seems IBM is very excited about neuromorphic computing. First, there’s an August 10, 2023 news article by Shiona McCallum & Chris Vallance for British Broadcasting Corporation (BBC) online news,
Concerns have been raised about emissions associated with warehouses full of computers powering AI systems.
IBM said its prototype could lead to more efficient, less battery draining AI chips for smartphones.
Its efficiency is down to components that work in a similar way to connections in human brains, it said.
Compared to traditional computers, “the human brain is able to achieve remarkable performance while consuming little power”, said scientist Thanos Vasilopoulos, based at IBM’s research lab in Zurich, Switzerland.
Most chips are digital, meaning they store information as 0s and 1s, but the new chip uses components called memristors [memory resistors] that are analogue and can store a range of numbers.
You can think of the difference between digital and analogue as like the difference between a light switch and a dimmer switch.
The human brain is analogue, and the way memristors work is similar to the way synapses in the brain work.
Prof Ferrante Neri, from the University of Surrey, explains that memristors fall into the realm of what you might call nature-inspired computing that mimics brain function.
A memristor could “remember” its electric history, in a similar way to a synapse in a biological system.
“Interconnected memristors can form a network resembling a biological brain,” he said.
He was cautiously optimistic about the future for chips using this technology: “These advancements suggest that we may be on the cusp of witnessing the emergence of brain-like chips in the near future.”
However, he warned that developing a memristor-based computer is not a simple task and that there would be a number of challenges ahead for widespread adoption, including the costs of materials and manufacturing difficulties.
…
Neri is most likely aware that researchers have been excited that ‘green’ computing could be made possible by memristors since at least 2008 (see my May 9, 2008 posting “Memristors and green energy“).
As it turns out, IBM published two studies on neuromorphic chips in August 2023.
The first study (mentioned in the BBC article) is also described in an August 22, 2023 article by Peter Grad for Tech Xpore. This one is a little more technical than the BBC article,
For those who are truly technical, here’s a link to and a citation for the paper,
A 64-core mixed-signal in-memory compute chip based on phase-change memory for deep neural network inference by Manuel Le Gallo, Riduan Khaddam-Aljameh, Milos Stanisavljevic, Athanasios Vasilopoulos, Benedikt Kersting, Martino Dazzi, Geethan Karunaratne, Matthias Brändli, Abhairaj Singh, Silvia M. Müller, Julian Büchel, Xavier Timoneda, Vinay Joshi, Malte J. Rasch, Urs Egger, Angelo Garofalo, Anastasios Petropoulos, Theodore Antonakopoulos, Kevin Brew, Samuel Choi, Injo Ok, Timothy Philip, Victor Chan, Claire Silvestre, Ishtiaq Ahsan, Nicole Saulnier, Nicole Saulnier, Pier Andrea Francese, Evangelos Eleftheriou & Abu Sebastian. Nature Electronics (2023) DOI: https://doi.org/10.1038/s41928-023-01010-1 Published: 10 August 2023
This paper is behind a paywall.
Before getting to the second paper, there’s an August 23, 2023 IBM blog post by Mike Murphy announcing its publication in Nature, Note: Links have been removed,
Although we’re still just at the precipice of the AI revolution, artificial intelligence has already begun to revolutionize the way we live and work. There’s just one problem: AI technology is incredibly power-hungry. By some estimates, running a large AI model generates more emissions over its lifetime than the average American car.
The future of AI requires new innovations in energy efficiency, from the way models are designed down to the hardware that runs them. And in a world that’s increasingly threatened by climate change, any advances in AI energy efficiency are essential to keep pace with AI’s rapidly expanding carbon footprint.
And one of the latest breakthroughs in AI efficiency from IBM Research relies on analog chips — ones that consume much less power. In a paper published in Nature today,1 researchers from IBM labs around the world presented their prototype analog AI chip for energy-efficient speech recognition and transcription. Their design was utilized in two AI inference experiments, and in both cases, the analog chips performed these tasks just as reliably as comparable all-digital devices — but finished the tasks faster and used less energy.
The concept of designing analog chips for AI inference is not new — researchers have been contemplating the idea for years. Back in 2021, a team at IBM developed chips that use Phase-change memory (PCM) works when an electrical pulse is applied to a material, which changes the conductance of the device. The material switches between amorphous and crystalline phases, where a lower electrical pulse will make the device more crystalline, providing less resistance, and a high enough electrical pulse makes the device amorphous, resulting in large resistance. Instead of recording the usual 0s or 1s you would see in digital systems, the PCM device records its state as a continuum of values between the amorphous and crystalline states. This value is called a synaptic weight, which can be stored in the physical atomic configuration of each PCM device. The memory is non-volatile, so the weights are retained when the power supply is switched off.phase-change memory to encode the weights of a neural network directly onto the physical chip. But previous research in the field hasn’t shown how chips like these could be used on the massive models we see dominating the AI landscape today. For example, GPT-3, one of the larger popular models, has 175 billion parameters, or weights.
Murphy also explains the difference (for amateurs like me) between this work and the earlier published study, from the August 23, 2023 IBM blog post, Note: Links have been removed,
Natural-language tasks aren’t the only AI problems that analog AI could solve — IBM researchers are working on a host of other uses. In a paper published earlier this month in Nature Electronics, the team showed it was possible to use an energy-efficient analog chip design for scalable mixed-signal architecture that can achieve high accuracy in the CIFAR-10 image dataset for computer vision image recognition.
These chips were conceived and designed by IBM researchers in the Tokyo, Zurich, Yorktown Heights, New York, and Almaden, California labs, and built by an external fabrication company. The phase change memory and metal levels were processed and validated at IBM Research’s lab in the Albany Nanotech Complex.
If you were to combine the benefits of the work published today in Nature, such as large arrays and parallel data-transport, with the capable digital compute-blocks of the chip shown in the Nature Electronics paper, you would see many of the building blocks needed to realize the vision of a fast, low-power analog AI inference accelerator. And pairing these designs with hardware-resilient training algorithms, the team expects these AI devices to deliver the software equivalent of neural network accuracies for a wide range of AI models in the future.
…
Here’s a link to and a citation for the second paper,
An analog-AI chip for energy-efficient speech recognition and transcription by S. Ambrogio, P. Narayanan, A. Okazaki, A. Fasoli, C. Mackin, K. Hosokawa, A. Nomura, T. Yasuda, A. Chen, A. Friz, M. Ishii, J. Luquin, Y. Kohda, N. Saulnier, K. Brew, S. Choi, I. Ok, T. Philip, V. Chan, C. Silvestre, I. Ahsan, V. Narayanan, H. Tsai & G. W. Burr. Nature volume 620, pages 768–775 (2023) DOI: https://doi.org/10.1038/s41586-023-06337-5 Published: 23 August 2023 Issue Date: 24 August 2023
It seems that Canadian nuclear energy company General Fusion has finally moved from Burnaby to Richmond (both are part of the Metro Vancouver Region). The move first announced in 2021 (see my November 3, 2021 posting for the news and a description of fusion energy; Note: fission is a different form of nuclear energy, fusion is considered clean/green).
I found confirmation of the move in an August 9, 2023 article by Kenneth Chan for the dailyhive.com
If all goes as planned, a major hurdle in fusion-based, zero-emission clean energy innovation could be produced on Sea Island in Richmond in just three years from now.
BC-based General Fusion announced today it has plans to build a new magnetized target fusion (MTF) machine at the company’s global headquarters at 6020-6082 Russ Baker Way [emphasis mine] near the South Terminal of Vancouver International Airport (YVR). [Note: YVR is located in Richmond, BC]
This machine will be designed to achieve fusion conditions of over 100,000,000°C by 2025, with “scientific breakeven” conditions by 2026. This will “fast-track” the company’s technical progress.
More specifically, this further proof-of-concept will show General Fusion’s ability to “symmetrically compress magnetized plasmas in a repeatable manner and achieve fusion conditions at scale.”
General Fusion’s technology is designed to be lower cost by avoiding other approaches that require expensive superconducting magnets or high-powered lasers.
…
The YVR machine is intended to support further work and investment and reduce the risk of General Fusion’s commercial-scale demonstration test plan in Culham Campus of the United Kingdom Atomic Energy Authority (UKAEA) — located just outside of Oxford, west of London. The UK plant has effectively been delayed, [emphasis mine] with the goal now to provide electricity to the grid with commercial fusion energy by the early to mid-2030s.
“Our updated three-year Fusion Demonstration Program puts us on the best path forward to commercialize our technology by the 2030s,” said Greg Twinney, CEO of General Fusion, in a statement. “We’re harnessing our team’s existing strengths right here in Canada and delivering high-value, industry-leading technical milestones in the near term.”
…
Canada, always a colony
I wonder what happened to the UKAEA deal. In my October 28, 2022 posting (Overview of fusion energy scene) General Fusion was downright effusive in its enthusiasm about the joint path to commercialization with a demonstration machine to be built in the UK. Scroll down to my ‘Fusion energy explanation (2)’ subhead for more details.
General Fusion announced a new Magnetized Target Fusion (MTF) machine that will fast-track the company’s technical progress. To be built at the company’s new Richmond headquarters, this ground-breaking machine is designed to achieve fusion conditions of over 100 million degrees Celsius by 2025, [emphasis mine] and progress toward scientific breakeven by 2026. In addition, the company completed the first close of its Series F raise for a combined $25 million USD (approximately $33.5 million CAD) of funding. The round was anchored by existing investors, BDC Capital and GIC. It also included new grant funding from the Government of British Columbia, which builds upon the Canadian government’s ongoing support through the Strategic Innovation Fund (SIF).
This machine represents a significant new pillar to accelerate and de-risk [emphasis mine] General Fusion’s Demonstration Program, designed to leverage the company’s recent technological advancements and provide electricity to the grid with commercial fusion energy by the early to mid-2030s.
…
Over the next two to three years, General Fusion will work closely with the UK Atomic Energy Authority [UKAEA] to validate the data gathered from [Lawson Machine 26] LM26 and incorporate it into the design of the company’s planned commercial scale demonstration in the UK.
…
So, the machine is being ‘de-risked’ in Canada first, eh?
September 2023
There was an interesting UK addition to General Fusion’s board of directors according to a September 6, 2023 news release,
Today [September 6, 2023], General Fusion announced the appointment of Norman Harrison to its Board of Directors. Norman is a world-class executive in the energy sector, with 40 years of unique experience providing leadership to both the fusion energy and nuclear fission communities.
His experience includes serving as the CEO of the UK Atomic Energy Authority (UKAEA) from 2006 to 2010 [emphasis mine], when he oversaw the groundbreaking research being conducted by the Joint European Torus (JET), the world’s largest fusion experiment and the only one operating using deuterium-tritium fuel, as it pushed the frontiers of fusion science. Norman’s expertise will support General Fusion as the company completes its Magnetized Target Fusion (MTF) demonstration, LM26 [scroll up to August 9, 2023 news release in the above for details] , at its Canadian headquarters. LM26 is targeting fusion conditions of 100 million degrees Celsius by 2025 and is charting a path to scientific breakeven equivalent by 2026. The results achieved by LM26 will be validated by the UKAEA and incorporated into the design of the company’s near-commercial machine, which is planned to be built at the UKAEA’s Culham Campus.
Norman’s background also includes leading the construction and operations of large-scale power plants. As a result, his guidance will benefit General Fusion as it progresses to commercializing its MTF technology by the early to mid-2030s.
“I’ve been a part of the fusion energy industry for many years now. General Fusion’s unique technology stands out and has exciting promise to put fusion energy onto the electricity grid,” said Norman Harrison. “I am thrilled to join the General Fusion team and be a part of the company’s progress.”
“Norman’s wealth of expertise in advancing fusion technology and operating large electricity infrastructure provides us with meaningful insight into what is required to effectively bring Magnetized Target Fusion to the energy grid in a cost-effective, practical way,” said Greg Twinney, CEO, General Fusion. “We look forward to working with him as General Fusion transforms the commercial power industry with reliable fusion power.”
About General Fusion
General Fusion is pursuing a fast and practical approach to commercial fusion energy and is headquartered in Richmond, B.C. The company was established in 2002 and is funded by a global syndicate of leading energy venture capital firms, industry leaders and technology pioneers. …
So, after postponing plans to build a build a demonstration plant with UKAEA and deciding to build it in Canada where it can be ‘de-risked’ here first, General Fusion adds a former UKAEA CEO to their company board. This seems a little strategic to me.
Today [October 11, 2023], General Fusion and Kyoto Fusioneering announced a Memorandum of Understanding (MOU) to accelerate the commercialization of General Fusion’s proprietary Magnetized Target Fusion (MTF) technology, aiming for grid integration in the early to mid-2030s. The companies will collaborate to advance critical systems for MTF commercialization, including the tritium fuel cycle, liquid metal balance of plant, and power conversion cycle.
Tritium, a hydrogen isotope and key fusion fuel, does not occur naturally and must be produced or “bred” in the fusion process. General Fusion’s game-changing commercial power plant design features a proprietary liquid metal wall that compresses plasma to fusion conditions, protects the fusion machine’s vessel components, and breeds tritium upon interacting with the fusion products. This design allows the machine to be self-sustaining, generating fuel for the life of the power plant while facilitating efficient energy extraction from the fusion reaction through a liquid metal loop to a heat exchanger.
Kyoto Fusioneering specializes in fusion power plant systems that complement the plasma confinement core, are applicable to various fusion confinement concepts, such as MTF, and are on the critical path for fusion commercialization. The complementary capabilities of both organizations will enable parallel development of key systems supporting MTF commercialization. Initial collaboration under this MOU will focus on liquid metal experimentation and fuel cycle system development at both the General Fusion and Kyoto Fusioneering facilities, such as establishment of balance of plant and power conversion test facilities, liquid metal loops, and vacuum systems.
Quotes:
“Currently, our new machine, LM26, is on-track to achieve fusion conditions by 2025, and progress towards scientific breakeven by 2026,” said Greg Twinney, CEO, General Fusion. “Harnessing the unique technological and engineering expertise of Kyoto Fusioneering will be instrumental as we translate LM26’s groundbreaking results into the world’s first Magnetized Target Fusion power plant.”
“We’re thrilled to join forces with General Fusion. Our combined expertise will accelerate the path to commercial fusion energy, a critical step toward a sustainable, decarbonized future,” said Satoshi Konishi, Co-founder and Chief Fusioneer, Kyoto Fusioneering.
Quick Facts:
Magnetized Target Fusion [prepare yourself for 1 min. 21 secs. of an enthusiastic Michel Laberge, company founder and chief science officer] uniquely sidesteps challenges to commercialization that other technologies face. The proprietary liquid metal liner in the commercial fusion machine is mechanically compressed by high-powered pistons. This enables fusion conditions to be created in short pulses rather than creating a sustained reaction. General Fusion’s design does not require large superconducting magnets or an expensive array of lasers.
General Fusion’s design will use deuterium-tritium fuel for its commercial power plant. Both are isotopes of hydrogen. Deuterium occurs naturally and can be derived from seawater. Tritium needs to be produced, which is why General Fusion’s unique and proprietary technology that breeds tritium as a byproduct of the fusion reaction is a game-changer.
Kyoto Fusioneering was spun out of Kyoto University. It is home to world-class R&D facilities, and its team has a combined total of approximately 800 years of experience [emphasis mine].
…
About Kyoto Fusioneering
Kyoto Fusioneering, established in 2019 [emphasis mine], is a privately funded technology startup with facilities in Tokyo and Kyoto (Japan), Reading (UK), and Seattle (USA). The company specialises in developing advanced technologies for commercial fusion power plants, such as gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. Working collaboratively with public and private fusion developers around the world, Kyoto Fusioneering’s mission is to make fusion energy the ultimate sustainable solution for humanity’s energy needs.
800 years of experience seems to be a bit of a stretch for a company established four years ago with 96 employees as of July 1, 2023 (see Kyoto Fusioneering’s Company Profile webpage) but hat’s off for the sheer gutsiness of it.
Credit: Pixabay/CC0 Public Domain [downloaded from https://phys.org/news/2023-08-anatomy-superheroic-science-class.html]
An August 9, 2023 news item on phys.org highlights how superhero anatomy is being employed in human anatomy courses, Note: A link has been removed,
What do superheroes Deadpool and Elastigirl have in common? Each was used in a college anatomy class to add relevance to course discussions—Deadpool to illustrate tissue repair, and Elastigirl, aka Mrs. Incredible, as an example of hyperflexibility.
Instructors at The Ohio State University College of Medicine created a “SuperAnatomy” course in an attempt to improve the experience of undergraduate students learning the notoriously difficult—and for some, scary or gross—subject matter of human anatomy.
Surveys showed that most students who took the class found the use of superheroes increased their motivation to learn, fostered deeper understanding of the material, and made the content more approachable and enjoyable.
A few of the many content examples also included considering how Wolverine’s claws would affect his musculoskeletal system and citing Groot in a discussion of skin disorders.The effort was aimed at bringing creativity to the classroom – in the form of outside-the-box instruction and as a way to inspire students’ imagination and keep them engaged, said Melissa Quinn, associate professor of anatomy at Ohio State and senior author of a study on the course’s effectiveness.
“In these introductory courses, it’s a little tougher to talk about clinical relevance because students don’t fully understand a lot of the mechanics,” Quinn said. “But if you bring in pop culture, which everybody is inundated with in some way, shape or form, and tie it to the foundational sciences, then that becomes a way to apply it a little bit more.”
The study was published recently in the journal Anatomical Sciences Education.
First author Jeremy Grachan, the mastermind behind the course’s creation, led design of the curriculum as an Ohio State PhD student and is now an assistant professor of anatomy at Rutgers New Jersey Medical School.
SuperAnatomy was created as a 1000-level three-credit-hour undergraduate course open to students of all majors. The class consisted of three 55-minute lectures each week and lab sessions offered twice in the semester. The course’s curriculum borrowed heavily from Human Anatomy 2300, a four-credit-hour course taken primarily by pre-health profession majors, consisting of live and recorded lectures, review sessions and one lab per week.
Students from both classes were invited to join the study over three semesters in 2021 and 2022; 36 students in SuperAnatomy and 442 students in Human Anatomy participated. Researchers collected data from 50-question quizzes given during the first week of classes and at the end of the semester intended to gauge how well students learned and applied course content. The students also completed pre- and post-course surveys.
The quiz results showed that student learning and application of material in the two courses was essentially the same. And to be clear, the SuperAnatomy content was not all cartoons and comic books.
“We looked at courses already running in our anatomy curriculum and took the relevant parts of those courses and added in the superheroes,” Quinn said. “So we actually elevated the curriculum.”
The follow-up survey of SuperAnatomy participants suggested the inclusion of superheroes strengthened their class experience, with nearly all students reporting that pop culture and superhero references expanded their understanding of course material and boosted their motivation to do well in the class.
“Collectively, if the students are enjoying the course and motivated to learn the material it could be better not only for their academic success, but their mental health and social wellbeing too,” the authors wrote.
Human anatomy is tough stuff – on top of the high volume of unfamiliar medical terms rooted in Latin, it can be unsettling to learn about the body in such a scientific, yet intimate, way.
“If you don’t have a good tour guide to help you, you might be inclined to give up pretty quickly,” Quinn said. “And none of us wants to be stale in our teaching.
“Here, we’ve seen that you can take a course like anatomy, which has been around forever, and bring it very much to whatever generation that we’re going to be teaching. And it’s not just about having fun – but a way to really make anatomy very interesting.”
Mason Marek and James Cray Jr. of Ohio State also co-authored the study.
For the first time in the 15 years this blog has been around, the Nobel prizes awarded in medicine, physics, and chemistry all are in areas discussed here at one or another. As usual where people are concerned, some of these scientists had a tortuous journey to this prestigious outcome.
Medicine
Two people (Katalin Karikó and Drew Weissman) were awarded the prize in medicine according to the October 2, 2023 Nobel Prize press release, Note: Links have been removed,
The Nobel Assembly at Karolinska Institutet [Sweden]
has today decided to award
the 2023 Nobel Prize in Physiology or Medicine
jointly to
Katalin Karikó and Drew Weissman
for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19
The discoveries by the two Nobel Laureates were critical for developing effective mRNA vaccines against COVID-19 during the pandemic that began in early 2020. Through their groundbreaking findings, which have fundamentally changed our understanding of how mRNA interacts with our immune system, the laureates contributed to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times.
Vaccines before the pandemic
Vaccination stimulates the formation of an immune response to a particular pathogen. This gives the body a head start in the fight against disease in the event of a later exposure. Vaccines based on killed or weakened viruses have long been available, exemplified by the vaccines against polio, measles, and yellow fever. In 1951, Max Theiler was awarded the Nobel Prize in Physiology or Medicine for developing the yellow fever vaccine.
Thanks to the progress in molecular biology in recent decades, vaccines based on individual viral components, rather than whole viruses, have been developed. Parts of the viral genetic code, usually encoding proteins found on the virus surface, are used to make proteins that stimulate the formation of virus-blocking antibodies. Examples are the vaccines against the hepatitis B virus and human papillomavirus. Alternatively, parts of the viral genetic code can be moved to a harmless carrier virus, a “vector.” This method is used in vaccines against the Ebola virus. When vector vaccines are injected, the selected viral protein is produced in our cells, stimulating an immune response against the targeted virus.
Producing whole virus-, protein- and vector-based vaccines requires large-scale cell culture. This resource-intensive process limits the possibilities for rapid vaccine production in response to outbreaks and pandemics. Therefore, researchers have long attempted to develop vaccine technologies independent of cell culture, but this proved challenging.
In our cells, genetic information encoded in DNA is transferred to messenger RNA (mRNA), which is used as a template for protein production. During the 1980s, efficient methods for producing mRNA without cell culture were introduced, called in vitro transcription. This decisive step accelerated the development of molecular biology applications in several fields. Ideas of using mRNA technologies for vaccine and therapeutic purposes also took off, but roadblocks lay ahead. In vitro transcribed mRNA was considered unstable and challenging to deliver, requiring the development of sophisticated carrier lipid systems to encapsulate the mRNA. Moreover, in vitro-produced mRNA gave rise to inflammatory reactions. Enthusiasm for developing the mRNA technology for clinical purposes was, therefore, initially limited.
These obstacles did not discourage the Hungarian biochemist Katalin Karikó, who was devoted to developing methods to use mRNA for therapy. During the early 1990s, when she was an assistant professor at the University of Pennsylvania, she remained true to her vision of realizing mRNA as a therapeutic despite encountering difficulties in convincing research funders of the significance of her project. A new colleague of Karikó at her university was the immunologist Drew Weissman. He was interested in dendritic cells, which have important functions in immune surveillance and the activation of vaccine-induced immune responses. Spurred by new ideas, a fruitful collaboration between the two soon began, focusing on how different RNA types interact with the immune system.
The breakthrough
Karikó and Weissman noticed that dendritic cells recognize in vitro transcribed mRNA as a foreign substance, which leads to their activation and the release of inflammatory signaling molecules. They wondered why the in vitro transcribed mRNA was recognized as foreign while mRNA from mammalian cells did not give rise to the same reaction. Karikó and Weissman realized that some critical properties must distinguish the different types of mRNA.
RNA contains four bases, abbreviated A, U, G, and C, corresponding to A, T, G, and C in DNA, the letters of the genetic code. Karikó and Weissman knew that bases in RNA from mammalian cells are frequently chemically modified, while in vitro transcribed mRNA is not. They wondered if the absence of altered bases in the in vitro transcribed RNA could explain the unwanted inflammatory reaction. To investigate this, they produced different variants of mRNA, each with unique chemical alterations in their bases, which they delivered to dendritic cells. The results were striking: The inflammatory response was almost abolished when base modifications were included in the mRNA. This was a paradigm change in our understanding of how cells recognize and respond to different forms of mRNA. Karikó and Weissman immediately understood that their discovery had profound significance for using mRNA as therapy. These seminal results were published in 2005, fifteen years before the COVID-19 pandemic.
In further studies published in 2008 and 2010, Karikó and Weissman showed that the delivery of mRNA generated with base modifications markedly increased protein production compared to unmodified mRNA. The effect was due to the reduced activation of an enzyme that regulates protein production. Through their discoveries that base modifications both reduced inflammatory responses and increased protein production, Karikó and Weissman had eliminated critical obstacles on the way to clinical applications of mRNA.
mRNA vaccines realized their potential
Interest in mRNA technology began to pick up, and in 2010, several companies were working on developing the method. Vaccines against Zika virus and MERS-CoV were pursued; the latter is closely related to SARS-CoV-2. After the outbreak of the COVID-19 pandemic, two base-modified mRNA vaccines encoding the SARS-CoV-2 surface protein were developed at record speed. Protective effects of around 95% were reported, and both vaccines were approved as early as December 2020.
The impressive flexibility and speed with which mRNA vaccines can be developed pave the way for using the new platform also for vaccines against other infectious diseases. In the future, the technology may also be used to deliver therapeutic proteins and treat some cancer types.
Several other vaccines against SARS-CoV-2, based on different methodologies, were also rapidly introduced, and together, more than 13 billion COVID-19 vaccine doses have been given globally. The vaccines have saved millions of lives and prevented severe disease in many more, allowing societies to open and return to normal conditions. Through their fundamental discoveries of the importance of base modifications in mRNA, this year’s Nobel laureates critically contributed to this transformative development during one of the biggest health crises of our time.
Katalin Karikó was born in 1955 in Szolnok, Hungary. She received her PhD from Szeged’s University in 1982 and performed postdoctoral research at the Hungarian Academy of Sciences in Szeged until 1985. She then conducted postdoctoral research at Temple University, Philadelphia, and the University of Health Science, Bethesda. In 1989, she was appointed Assistant Professor at the University of Pennsylvania, where she remained until 2013. After that, she became vice president and later senior vice president at BioNTech RNA Pharmaceuticals. Since 2021, she has been a Professor at Szeged University and an Adjunct Professor at Perelman School of Medicine at the University of Pennsylvania.
Drew Weissman was born in 1959 in Lexington, Massachusetts, USA. He received his MD, PhD degrees from Boston University in 1987. He did his clinical training at Beth Israel Deaconess Medical Center at Harvard Medical School and postdoctoral research at the National Institutes of Health. In 1997, Weissman established his research group at the Perelman School of Medicine at the University of Pennsylvania. He is the Roberts Family Professor in Vaccine Research and Director of the Penn Institute for RNA Innovations.
The University of Pennsylvania messenger RNA pioneers whose years of scientific partnership unlocked understanding of how to modify mRNA to make it an effective therapeutic—enabling a platform used to rapidly develop lifesaving vaccines amid the global COVID-19 pandemic—have been named winners of the 2023 Nobel Prize in Physiology or Medicine. They become the 28th and 29th Nobel laureates affiliated with Penn, and join nine previous Nobel laureates with ties to the University of Pennsylvania who have won the Nobel Prize in Medicine.
Nearly three years after the rollout of mRNA vaccines across the world, Katalin Karikó, PhD, an adjunct professor of Neurosurgery in Penn’s Perelman School of Medicine, and Drew Weissman, MD, PhD, the Roberts Family Professor of Vaccine Research in the Perelman School of Medicine, are recipients of the prize announced this morning by the Nobel Assembly in Solna, Sweden.
After a chance meeting in the late 1990s while photocopying research papers, Karikó and Weissman began investigating mRNA as a potential therapeutic. In 2005, they published a key discovery: mRNA could be altered and delivered effectively into the body to activate the body’s protective immune system. The mRNA-based vaccines elicited a robust immune response, including high levels of antibodies that attack a specific infectious disease that has not previously been encountered. Unlike other vaccines, a live or attenuated virus is not injected or required at any point.
When the COVID-19 pandemic struck, the true value of the pair’s lab work was revealed in the most timely of ways, as companies worked to quickly develop and deploy vaccines to protect people from the virus. Both Pfizer/BioNTech and Moderna utilized Karikó and Weissman’s technology to build their highly effective vaccines to protect against severe illness and death from the virus. In the United States alone, mRNA vaccines make up more than 655 million total doses of SARS-CoV-2 vaccines that have been administered since they became available in December 2020.
…
Editor’s Note:The Pfizer/BioNTech and Moderna COVID-19 mRNA vaccines both use licensed University of Pennsylvania technology. As a result of these licensing relationships, Penn, Karikó and Weissman have received and may continue to receive significant financial benefits in the future based on the sale of these products. BioNTech provides funding for Weissman’s research into the development of additional infectious disease vaccines.
Science can be brutal
Now for the interesting bit: it’s in my March 5, 2021 posting (mRNA, COVID-19 vaccines, treating genetic diseases before birth, and the scientist who started it all),
…
Before messenger RNA was a multibillion-dollar idea, it was a scientific backwater. And for the Hungarian-born scientist behind a key mRNA discovery, it was a career dead-end.
Katalin Karikó spent the 1990s collecting rejections. Her work, attempting to harness the power of mRNA to fight disease, was too far-fetched for government grants, corporate funding, and even support from her own colleagues.
…
“Every night I was working: grant, grant, grant,” Karikó remembered, referring to her efforts to obtain funding. “And it came back always no, no, no.”
By 1995, after six years on the faculty at the University of Pennsylvania, Karikó got demoted. [emphasis mine] She had been on the path to full professorship, but with no money coming in to support her work on mRNA, her bosses saw no point in pressing on.
She was back to the lower rungs of the scientific academy.
“Usually, at that point, people just say goodbye and leave because it’s so horrible,” Karikó said.
There’s no opportune time for demotion, but 1995 had already been uncommonly difficult. Karikó had recently endured a cancer scare, and her husband was stuck in Hungary sorting out a visa issue. Now the work to which she’d devoted countless hours was slipping through her fingers.
…
In time, those better experiments came together. After a decade of trial and error, Karikó and her longtime collaborator at Penn — Drew Weissman [emphasis mine], an immunologist with a medical degree and Ph.D. from Boston University — discovered a remedy for mRNA’s Achilles’ heel.
…
You can get the whole story from my March 5, 2021 posting, scroll down to the “mRNA—it’s in the details, plus, the loneliness of pioneer researchers, a demotion, and squabbles” subhead. If you are very curious about mRNA and the rough and tumble of the world of science, there’s my August 20, 2021 posting “Getting erased from the mRNA/COVID-19 story” where Ian MacLachlan is featured as a researcher who got erased and where Karikó credits his work.
Karikó’s daughter is a two-time gold medal Olympic athlete as the Canadian Broadcasting Corporation’s (CBC) radio programme, As It Happens, notes in an interview with the daughter (Susan Francia). From an October 4, 2023 As It Happens article (with embedded audio programme excerpt) by Sheena Goodyear,
Olympic gold medallist Susan Francia is coming to terms with the fact that she’s no longer the most famous person in her family.
That’s because the retired U.S. rower’s mother, Katalin Karikó, just won a Nobel Prize in Medicine. The biochemist was awarded alongside her colleague, vaccine researcher Drew Weissman, for their groundbreaking work that led to the development of COVID-19 vaccines.
“Now I’m like, ‘Shoot! All right, I’ve got to work harder,'” Francia said with a laugh during an interview with As It Happens host Nil Köksal.
But in all seriousness, Francia says she’s immensely proud of her mother’s accomplishments. In fact, it was Karikó’s fierce dedication to science that inspired Francia to win Olympic gold medals in 2008 and 2012.
“Sport is a lot like science in that, you know, you have a passion for something and you just go and you train, attain your goal, whether it be making this discovery that you truly believe in, or for me, it was trying to be the best in the world,” Francia said.
“It’s a grind and, honestly, I love that grind. And my mother did too.”
…
… one of her [Karikó] favourite headlines so far comes from a little blurb on the rowing website Row 2K: “Rowing Mom Wins Nobel.”
…
Nowadays, scientists are trying to harness the power of mRNA to fight cancer, malaria, influenza and rabies. But when Karikó first began her work, it was a fringe concept. For decades, she toiled in relative obscurity, struggling to secure funding for her research.
“That’s also that same passion that I took into my rowing,” Francia said.
But even as Karikó struggled to make a name for herself, she says her own mother, Zsuzsanna, always believed she would earn a Nobel Prize one day.
Every year, as the Nobel Prize announcement approached, she would tell Karikó she’d be watching for her name.
“I was laughing [and saying] that, ‘Mom, I am not getting anything,'” she said.
But her mother, who died a few years ago, ultimately proved correct.
…
Congratulations to both Katalin Karikó and Drew Weissman and thank you both for persisting!
Physics
This prize is for physics at the attoscale.
Aaron W. Harrison (Assistant Professor of Chemistry, Austin College, Texas, US) attempts an explanation of an attosecond in his October 3, 2023 essay (in English “What is an attosecond? A physical chemist explains the tiny time scale behind Nobel Prize-winning research” and in French “Nobel de physique : qu’est-ce qu’une attoseconde?”) for The Conversation, Note: Links have been removed,
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“Atto” is the scientific notation prefix that represents 10-18, which is a decimal point followed by 17 zeroes and a 1. So a flash of light lasting an attosecond, or 0.000000000000000001 of a second, is an extremely short pulse of light.
In fact, there are approximately as many attoseconds in one second as there are seconds in the age of the universe.
Previously, scientists could study the motion of heavier and slower-moving atomic nuclei with femtosecond (10-15) light pulses. One thousand attoseconds are in 1 femtosecond. But researchers couldn’t see movement on the electron scale until they could generate attosecond light pulses – electrons move too fast for scientists to parse exactly what they are up to at the femtosecond level.
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Harrison does a very good job of explaining something that requires a leap of imagination. He also explains why scientists engage in attosecond research. h/t October 4, 2023 news item on phys.org
Amelle Zaïr (Imperial College London) offers a more technical explanation in her October 4, 2023 essay about the 2023 prize winners for The Conversation. h/t October 4, 2023 news item on phys.org
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Physics 2023 to
Pierre Agostini The Ohio State University, Columbus, USA
Ferenc Krausz Max Planck Institute of Quantum Optics, Garching and Ludwig-Maximilians-Universität München, Germany
Anne L’Huillier Lund University, Sweden
“for experimental methods that generate attosecond pulses of light for the study of electron dynamics in matter”
Experiments with light capture the shortest of moments
The three Nobel Laureates in Physics 2023 are being recognised for their experiments, which have given humanity new tools for exploring the world of electrons inside atoms and molecules. Pierre Agostini, Ferenc Krausz and Anne L’Huillier have demonstrated a way to create extremely short pulses of light that can be used to measure the rapid processes in which electrons move or change energy.
Fast-moving events flow into each other when perceived by humans, just like a film that consists of still images is perceived as continual movement. If we want to investigate really brief events, we need special technology. In the world of electrons, changes occur in a few tenths of an attosecond – an attosecond is so short that there are as many in one second as there have been seconds since the birth of the universe.
The laureates’ experiments have produced pulses of light so short that they are measured in attoseconds, thus demonstrating that these pulses can be used to provide images of processes inside atoms and molecules.
In 1987, Anne L’Huillier discovered that many different overtones of light arose when she transmitted infrared laser light through a noble gas. Each overtone is a light wave with a given number of cycles for each cycle in the laser light. They are caused by the laser light interacting with atoms in the gas; it gives some electrons extra energy that is then emitted as light. Anne L’Huillier has continued to explore this phenomenon, laying the ground for subsequent breakthroughs.
In 2001, Pierre Agostini succeeded in producing and investigating a series of consecutive light pulses, in which each pulse lasted just 250 attoseconds. At the same time, Ferenc Krausz was working with another type of experiment, one that made it possible to isolate a single light pulse that lasted 650 attoseconds.
The laureates’ contributions have enabled the investigation of processes that are so rapid they were previously impossible to follow.
“We can now open the door to the world of electrons. Attosecond physics gives us the opportunity to understand mechanisms that are governed by electrons. The next step will be utilising them,” says Eva Olsson, Chair of the Nobel Committee for Physics.
There are potential applications in many different areas. In electronics, for example, it is important to understand and control how electrons behave in a material. Attosecond pulses can also be used to identify different molecules, such as in medical diagnostics.
Pierre Agostini. PhD 1968 from Aix-Marseille University, France. Professor at The Ohio State University, Columbus, USA.
Ferenc Krausz, born 1962 in Mór, Hungary. PhD 1991 from Vienna University of Technology, Austria. Director at Max Planck Institute of Quantum Optics, Garching and Professor at Ludwig-Maximilians-Universität München, Germany.
Anne L’Huillier, born 1958 in Paris, France. PhD 1986 from University Pierre and Marie Curie, Paris, France. Professor at Lund University, Sweden.
Three scientists have won the Nobel Prize in physics Tuesday for giving us the first split-second glimpse into the superfast world of spinning electrons, a field that could one day lead to better electronics or disease diagnoses.
The award went to French-Swedish physicist Anne L’Huillier, French scientist Pierre Agostini and Hungarian-born Ferenc Krausz for their work with the tiny part of each atom that races around the centre, and that is fundamental to virtually everything: chemistry, physics, our bodies and our gadgets.
Electrons move around so fast that they have been out of reach of human efforts to isolate them. But by looking at the tiniest fraction of a second possible, scientists now have a “blurry” glimpse of them, and that opens up whole new sciences, experts said.
“The electrons are very fast, and the electrons are really the workforce in everywhere,” Nobel Committee member Mats Larsson said. “Once you can control and understand electrons, you have taken a very big step forward.”
L’Huillier is the fifth woman to receive a Nobel in Physics.
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L’Huillier was teaching basic engineering physics to about 100 undergraduates at Lund when she got the call that she had won, but her phone was on silent and she didn’t pick up. She checked it during a break and called the Nobel Committee.
Then she went back to teaching.
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Agostini, an emeritus professor at Ohio State University, was in Paris and could not be reached by the Nobel Committee before it announced his win to the world
Krausz, of the Max Planck Institute of Quantum Optics and Ludwig Maximilian University of Munich, told reporters that he was bewildered.
“I have been trying to figure out since 11 a.m. whether I’m in reality or it’s just a long dream,” the 61-year-old said.
Last year, Krausz and L’Huillier won the prestigious Wolf prize in physics for their work, sharing it with University of Ottawa scientist Paul Corkum [emphasis mine]. Nobel prizes are limited to only three winners and Krausz said it was a shame that it could not include Corkum.
Corkum was key to how the split-second laser flashes could be measured [emphasis mine], which was crucial, Krausz said.
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Congratulations to Pierre Agostini, Ferenc Krausz and Anne L’Huillier and a bow to Paul Corkum!
For those who are curious. a ‘Paul Corkum’ search should bring up a few postings on this blog but I missed this piece of news, a May 4, 2023 University of Ottawa news release about Corkum and the 2022 Wolf Prize, which he shared with Krausz and L’Huillier,
Chemistry
There was a little drama where this prize was concerned, It was announced too early according to an October 4, 2023 news item on phys.org and, again, in another October 4, 2023 news item on phys.org (from the Oct. 4, 2023 news item by Karl Ritter for the Associated Press),
Oops! Nobel chemistry winners are announced early in a rare slip-up
The most prestigious and secretive prize in science ran headfirst into the digital era Wednesday when Swedish media got an emailed press release revealing the winners of the Nobel Prize in chemistry and the news prematurely went public.
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2023 to
Moungi G. Bawendi Massachusetts Institute of Technology (MIT), Cambridge, MA, USA
Louis E. Brus Columbia University, New York, NY, USA
Alexei I. Ekimov Nanocrystals Technology Inc., New York, NY, USA
“for the discovery and synthesis of quantum dots”
They planted an important seed for nanotechnology
The Nobel Prize in Chemistry 2023 rewards the discovery and development of quantum dots, nanoparticles so tiny that their size determines their properties. These smallest components of nanotechnology now spread their light from televisions and LED lamps, and can also guide surgeons when they remove tumour tissue, among many other things.
Everyone who studies chemistry learns that an element’s properties are governed by how many electrons it has. However, when matter shrinks to nano-dimensions quantum phenomena arise; these are governed by the size of the matter. The Nobel Laureates in Chemistry 2023 have succeeded in producing particles so small that their properties are determined by quantum phenomena. The particles, which are called quantum dots, are now of great importance in nanotechnology.
“Quantum dots have many fascinating and unusual properties. Importantly, they have different colours depending on their size,” says Johan Åqvist, Chair of the Nobel Committee for Chemistry.
Physicists had long known that in theory size-dependent quantum effects could arise in nanoparticles, but at that time it was almost impossible to sculpt in nanodimensions. Therefore, few people believed that this knowledge would be put to practical use.
However, in the early 1980s, Alexei Ekimov succeeded in creating size-dependent quantum effects in coloured glass. The colour came from nanoparticles of copper chloride and Ekimov demonstrated that the particle size affected the colour of the glass via quantum effects.
A few years later, Louis Brus was the first scientist in the world to prove size-dependent quantum effects in particles floating freely in a fluid.
In 1993, Moungi Bawendi revolutionised the chemical production of quantum dots, resulting in almost perfect particles. This high quality was necessary for them to be utilised in applications.
Quantum dots now illuminate computer monitors and television screens based on QLED technology. They also add nuance to the light of some LED lamps, and biochemists and doctors use them to map biological tissue.
Quantum dots are thus bringing the greatest benefit to humankind. Researchers believe that in the future they could contribute to flexible electronics, tiny sensors, thinner solar cells and encrypted quantum communication – so we have just started exploring the potential of these tiny particles.
Moungi G. Bawendi, born 1961 in Paris, France. PhD 1988 from University of Chicago, IL, USA. Professor at Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Louis E. Brus, born 1943 in Cleveland, OH, USA. PhD 1969 from Columbia University, New York, NY, USA. Professor at Columbia University, New York, NY, USA.
Alexei I. Ekimov, born 1945 in the former USSR. PhD 1974 from Ioffe Physical-Technical Institute, Saint Petersburg, Russia. Formerly Chief Scientist at Nanocrystals Technology Inc., New York, NY, USA.
Proving yet again that scientists can have a bumpy trip to a Nobel prize, an October 4, 2023 news item on phys.org describes how one of the winners flunked his first undergraduate chemistry test, Note: Links have been removed,
Talk about bouncing back. MIT professor Moungi Bawendi is a co-winner of this year’s Nobel chemistry prize for helping develop “quantum dots”—nanoparticles that are now found in next generation TV screens and help illuminate tumors within the body.
But as an undergraduate, he flunked his very first chemistry exam, recalling that the experience nearly “destroyed” him.
The 62-year-old of Tunisian and French heritage excelled at science throughout high school, without ever having to break a sweat.
But when he arrived at Harvard University as an undergraduate in the late 1970s, he was in for a rude awakening.
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You can find more about the winners and quantum dots in an October 4, 2023 news item on Nanowerk and in Dr. Andrew Maynard’s (Professor of Advanced Technology Transitions, Arizona State University) October 4, 2023 essay for The Conversation (h/t October 4, 2023 news item on phys.org), Note: Links have been removed,
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This year’s prize recognizes Moungi Bawendi, Louis Brus and Alexei Ekimov for the discovery and development of quantum dots. For many years, these precisely constructed nanometer-sized particles – just a few hundred thousandths the width of a human hair in diameter – were the darlings of nanotechnology pitches and presentations. As a researcher and adviser on nanotechnology [emphasis mine], I’ve [Dr. Andrew Maynard] even used them myself when talking with developers, policymakers, advocacy groups and others about the promise and perils of the technology.
The origins of nanotechnology predate Bawendi, Brus and Ekimov’s work on quantum dots – the physicist Richard Feynman speculated on what could be possible through nanoscale engineering as early as 1959, and engineers like Erik Drexler were speculating about the possibilities of atomically precise manufacturing in the the 1980s. However, this year’s trio of Nobel laureates were part of the earliest wave of modern nanotechnology where researchers began putting breakthroughs in material science to practical use.
Quantum dots brilliantly fluoresce: They absorb one color of light and reemit it nearly instantaneously as another color. A vial of quantum dots, when illuminated with broad spectrum light, shines with a single vivid color. What makes them special, though, is that their color is determined by how large or small they are. Make them small and you get an intense blue. Make them larger, though still nanoscale, and the color shifts to red.
There’s also an October 4, 2023 overview article by Tekla S. Perry and Margo Anderson for the IEEE Spectrum about the magazine’s almost twenty-five years of reporting on quantum dots
Image credit: Brandon Palacio/IEEE Spectrum
Your Guide to the Newest Nobel Prize: Quantum Dots
What you need to know—and what we’ve reported—about this year’s Chemistry award
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It’s not a long article and it has a heavy focus on the IEEEE’s (Institute of Electrical and Electtronics Engineers) the road quantum dots have taken to become applications and being commercialized.
Congratulations to Moungi Bawendi, Louis Brus, and Alexei Ekimov!
This July 20, 2023 article by Bob Yirka for phys.org highlights some frugal science, Note: A link has been removed,
A team of bioengineers at Arizona State University has found a way to use a LEGO robot as a gradient mixer in one part of a process to create DNA origami nanostructures. In their paper published on the open-access site PLOS [Public Library of Science] ONE, the group describes how they made their mixer and its performance.
To create DNA origami structures, purification of DNA [deoxyribonucleic acid] origami nanostructures is required. This is typically done using rate-zone centrifugation, which involves the use of a relatively expensive piece of a machinery, a gradient mixer. In this new effort, the team at ASU has found that it is possible to build such a mixer using off-the-shelf LEGO kits.
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I found a video provided by MindSpark Media describing the process on YouTube,
I’d love to know who paid for the video and why. This is pretty slick and it’s not from the Arizona State University’s (ASU) media team.
MindSpark Media is an independent media unit focusing on all major Media & Marketing services that includes Media Buying and Selling activities, bringing out special features on various supplements/country reports and international features on topics of interest in association with various leading English & Arabic vernaculars in the UAE [United Arab Emirates] and across MENA [Middle East and North Africa].
MindSpark Media is a complete media-selling experience that offers its clientele a wholesome exposure to the best media brands in the country. We also offer an opportunity to meet up and interact with the top brass of the industry & corporates for their advertorial packages including one-to-one interviews with photo-shoot sessions etc.
MindSpark Media delivers client-tailored advertorials that includes their product advertisements, features and interviews published in the form of special reports, supplements & special features, which are released and distributed with top-notch publications in the UAE.
We also focus on advertising activities in the media-buying sector such as Print, Outdoor, TV, Radio and Corporate Video, e-commerce & web-designing for clients in the UAE, MENA and beyond.
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Perhaps the researchers are hoping to commercialize the work in some fashion? I couldn’t find any mention of a startup or other commercial entity but it’s a common practice these days in the US and, increasingly, many other countries.
Getting back to the research, here’s a link to and a citation for the paper,
it may be my imagination but it seems as if neuromorphic (brainlike) engineering research has really taken off in the last few years and, even with my lazy approach to finding articles, I’m having trouble keeping up.
This latest work comes from Japan according to an August 4, 2023 news item on Nanowerk, Note: A link has been removed,
A research team consisting of NIMS [National Institute for Materials Science] and the Tokyo University of Science has developed the fastest electric double layer transistor using a highly ion conductive ceramic thin film and a diamond thin film. This transistor may be used to develop energy-efficient, high-speed edge AI devices with a wide range of applications, including future event prediction and pattern recognition/determination in images (including facial recognition), voices and odors.
The research was published in Materials Today Advances (“Ultrafast-switching of an all-solid-state electric double layer transistor with a porous yttria-stabilized zirconia proton conductor and the application to neuromorphic computing”).
2. An electric double layer transistor works as a switch using electrical resistance changes caused by the charge and discharge of an electric double layer formed at the interface between the electrolyte and semiconductor. Because this transistor is able to mimic the electrical response of human cerebral neurons (i.e., acting as a neuromorphic transistor), its use in AI devices is potentially promising. However, existing electric double layer transistors are slow in switching between on and off states. The typical transition time ranges from several hundreds of microseconds to 10 milliseconds. Development of faster electric double layer transistors is therefore desirable.
3. This research team developed an electric double layer transistor by depositing ceramic (yttria-stabilized porous zirconia thin film) and diamond thin films with a high degree of precision using a pulsed laser, forming an electric double layer at the ceramic/diamond interface. The zirconia thin film is able to adsorb large amounts of water into its nanopores and allow hydrogen ions from the water to readily migrate through it, enabling the electric double layer to be rapidly charged and discharged. This electric double layer effect enables the transistor to operate very quickly. The team actually measured the speed at which the transistor operates by applying pulsed voltage to it and found that it operates 8.5 times faster than existing electric double layer transistors, setting a new world record. The team also confirmed the ability of this transistor to convert input waveforms into many different output waveforms with precision—a prerequisite for transistors to be compatible with neuromorphic AI devices.
4. This research project produced a new ceramic thin film technology capable of rapidly charging and discharging an electric double layer several nanometers in thickness. This is a major achievement in efforts to create practical, high-speed, energy-efficient AI-assisted devices. These devices, in combination with various sensors (e.g., smart watches, surveillance cameras and audio sensors), are expected to offer useful tools in various industries, including medicine, disaster prevention, manufacturing and security.
