Tag Archives: Kyoto University

General Fusion: update to October 10, 2023

It seems that Canadian nuclear energy company General Fusion has finally moved from Burnaby to Richmond (both are part of the Metro Vancouver Region). The move first announced in 2021 (see my November 3, 2021 posting for the news and a description of fusion energy; Note: fission is a different form of nuclear energy, fusion is considered clean/green).

I found confirmation of the move in an August 9, 2023 article by Kenneth Chan for the dailyhive.com

If all goes as planned, a major hurdle in fusion-based, zero-emission clean energy innovation could be produced on Sea Island in Richmond in just three years from now.

BC-based General Fusion announced today it has plans to build a new magnetized target fusion (MTF) machine at the company’s global headquarters at 6020-6082 Russ Baker Way [emphasis mine] near the South Terminal of Vancouver International Airport (YVR). [Note: YVR is located in Richmond, BC]

Chan goes on to note (from his August 9, 2023 article), Note: A link has been removed,

This machine will be designed to achieve fusion conditions of over 100,000,000°C by 2025, with “scientific breakeven” conditions by 2026. This will “fast-track” the company’s technical progress.

More specifically, this further proof-of-concept will show General Fusion’s ability to “symmetrically compress magnetized plasmas in a repeatable manner and achieve fusion conditions at scale.”

General Fusion’s technology is designed to be lower cost by avoiding other approaches that require expensive superconducting magnets or high-powered lasers.

The YVR machine is intended to support further work and investment and reduce the risk of General Fusion’s commercial-scale demonstration test plan in Culham Campus of the United Kingdom Atomic Energy Authority (UKAEA) — located just outside of Oxford, west of London. The UK plant has effectively been delayed, [emphasis mine] with the goal now to provide electricity to the grid with commercial fusion energy by the early to mid-2030s.

“Our updated three-year Fusion Demonstration Program puts us on the best path forward to commercialize our technology by the 2030s,” said Greg Twinney, CEO of General Fusion, in a statement. “We’re harnessing our team’s existing strengths right here in Canada and delivering high-value, industry-leading technical milestones in the near term.”

Canada, always a colony

I wonder what happened to the UKAEA deal. In my October 28, 2022 posting (Overview of fusion energy scene) General Fusion was downright effusive in its enthusiasm about the joint path to commercialization with a demonstration machine to be built in the UK. Scroll down to my ‘Fusion energy explanation (2)’ subhead for more details.

It now looks as if the first demonstration will be build and tested in Canada, from an August 9, 2023 General Fusion news release,

General Fusion announced a new Magnetized Target Fusion (MTF) machine that will fast-track the company’s technical progress. To be built at the company’s new Richmond headquarters, this ground-breaking machine is designed to achieve fusion conditions of over 100 million degrees Celsius by 2025, [emphasis mine] and progress toward scientific breakeven by 2026. In addition, the company completed the first close of its Series F raise for a combined $25 million USD (approximately $33.5 million CAD) of funding. The round was anchored by existing investors, BDC Capital and GIC. It also included new grant funding from the Government of British Columbia, which builds upon the Canadian government’s ongoing support through the Strategic Innovation Fund (SIF). 

This machine represents a significant new pillar to accelerate and de-risk [emphasis mine] General Fusion’s Demonstration Program, designed to leverage the company’s recent technological advancements and provide electricity to the grid with commercial fusion energy by the early to mid-2030s.  

Over the next two to three years, General Fusion will work closely with the UK Atomic Energy Authority [UKAEA] to validate the data gathered from [Lawson Machine 26] LM26 and incorporate it into the design of the company’s planned commercial scale demonstration in the UK.

So, the machine is being ‘de-risked’ in Canada first, eh?

September 2023

There was an interesting UK addition to General Fusion’s board of directors according to a September 6, 2023 news release,

Today [September 6, 2023], General Fusion announced the appointment of Norman Harrison to its Board of Directors. Norman is a world-class executive in the energy sector, with 40 years of unique experience providing leadership to both the fusion energy and nuclear fission communities.

His experience includes serving as the CEO of the UK Atomic Energy Authority (UKAEA) from 2006 to 2010 [emphasis mine], when he oversaw the groundbreaking research being conducted by the Joint European Torus (JET), the world’s largest fusion experiment and the only one operating using deuterium-tritium fuel, as it pushed the frontiers of fusion science. Norman’s expertise will support General Fusion as the company completes its Magnetized Target Fusion (MTF) demonstration, LM26 [scroll up to August 9, 2023 news release in the above for details] , at its Canadian headquarters. LM26 is targeting fusion conditions of 100 million degrees Celsius by 2025 and is charting a path to scientific breakeven equivalent by 2026. The results achieved by LM26 will be validated by the UKAEA and incorporated into the design of the company’s near-commercial machine, which is planned to be built at the UKAEA’s Culham Campus. 

Norman’s background also includes leading the construction and operations of large-scale power plants. As a result, his guidance will benefit General Fusion as it progresses to commercializing its MTF technology by the early to mid-2030s.

“I’ve been a part of the fusion energy industry for many years now. General Fusion’s unique technology stands out and has exciting promise to put fusion energy onto the electricity grid,” said Norman Harrison. “I am thrilled to join the General Fusion team and be a part of the company’s progress.”

“Norman’s wealth of expertise in advancing fusion technology and operating large electricity infrastructure provides us with meaningful insight into what is required to effectively bring Magnetized Target Fusion to the energy grid in a cost-effective, practical way,” said Greg Twinney, CEO, General Fusion. “We look forward to working with him as General Fusion transforms the commercial power industry with reliable fusion power.”

About General Fusion

General Fusion is pursuing a fast and practical approach to commercial fusion energy and is headquartered in Richmond, B.C. The company was established in 2002 and is funded by a global syndicate of leading energy venture capital firms, industry leaders and technology pioneers. …

So, after postponing plans to build a build a demonstration plant with UKAEA and deciding to build it in Canada where it can be ‘de-risked’ here first, General Fusion adds a former UKAEA CEO to their company board. This seems a little strategic to me.

October 2023

Here’s the latest from an October 10, 2023 news release,

Today [October 11, 2023], General Fusion and Kyoto Fusioneering announced a Memorandum of Understanding (MOU) to accelerate the commercialization of General Fusion’s proprietary Magnetized Target Fusion (MTF) technology, aiming for grid integration in the early to mid-2030s. The companies will collaborate to advance critical systems for MTF commercialization, including the tritium fuel cycle, liquid metal balance of plant, and power conversion cycle.

Tritium, a hydrogen isotope and key fusion fuel, does not occur naturally and must be produced or “bred” in the fusion process. General Fusion’s game-changing commercial power plant design features a proprietary liquid metal wall that compresses plasma to fusion conditions, protects the fusion machine’s vessel components, and breeds tritium upon interacting with the fusion products. This design allows the machine to be self-sustaining, generating fuel for the life of the power plant while facilitating efficient energy extraction from the fusion reaction through a liquid metal loop to a heat exchanger.

Kyoto Fusioneering specializes in fusion power plant systems that complement the plasma confinement core, are applicable to various fusion confinement concepts, such as MTF, and are on the critical path for fusion commercialization. The complementary capabilities of both organizations will enable parallel development of key systems supporting MTF commercialization. Initial collaboration under this MOU will focus on liquid metal experimentation and fuel cycle system development at both the General Fusion and Kyoto Fusioneering facilities, such as establishment of balance of plant and power conversion test facilities, liquid metal loops, and vacuum systems.

Quotes:

“Currently, our new machine, LM26, is on-track to achieve fusion conditions by 2025, and progress towards scientific breakeven by 2026,” said Greg Twinney, CEO, General Fusion. “Harnessing the unique technological and engineering expertise of Kyoto Fusioneering will be instrumental as we translate LM26’s groundbreaking results into the world’s first Magnetized Target Fusion power plant.”

“We’re thrilled to join forces with General Fusion. Our combined expertise will accelerate the path to commercial fusion energy, a critical step toward a sustainable, decarbonized future,” said Satoshi Konishi, Co-founder and Chief Fusioneer, Kyoto Fusioneering.

Quick Facts:

Magnetized Target Fusion [prepare yourself for 1 min. 21 secs. of an enthusiastic Michel Laberge, company founder and chief science officer] uniquely sidesteps challenges to commercialization that other technologies face. The proprietary liquid metal liner in the commercial fusion machine is mechanically compressed by high-powered pistons. This enables fusion conditions to be created in short pulses rather than creating a sustained reaction. General Fusion’s design does not require large superconducting magnets or an expensive array of lasers.

General Fusion’s design will use deuterium-tritium fuel for its commercial power plant. Both are isotopes of hydrogen. Deuterium occurs naturally and can be derived from seawater. Tritium needs to be produced, which is why General Fusion’s unique and proprietary technology that breeds tritium as a byproduct of the fusion reaction is a game-changer.

Kyoto Fusioneering was spun out of Kyoto University. It is home to world-class R&D facilities, and its team has a combined total of approximately 800 years of experience [emphasis mine].

About Kyoto Fusioneering

Kyoto Fusioneering, established in 2019 [emphasis mine], is a privately funded technology startup with facilities in Tokyo and Kyoto (Japan), Reading (UK), and Seattle (USA). The company specialises in developing advanced technologies for commercial fusion power plants, such as gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. Working collaboratively with public and private fusion developers around the world, Kyoto Fusioneering’s mission is to make fusion energy the ultimate sustainable solution for humanity’s energy needs.

800 years of experience seems to be a bit of a stretch for a company established four years ago with 96 employees as of July 1, 2023 (see Kyoto Fusioneering’s Company Profile webpage) but hat’s off for the sheer gutsiness of it.

Algorithmic haiku: Basho in the machine

There is a lot of anxiety about artificial intelligence in the arts, which can only be exacerbated by a question such as this, from a December 2, 2022 news item on ScienceDaily,

Can artificial intelligence write better poetry than humans?

The gap between human creativity and artificial intelligence seems to be narrowing. Previous studies have compared AI-generated versus human-written poems and whether people can distinguish between them.

The answer doesn’t seem all that comforting and a December 2, 2022 Kyoto University press release (also on EurekAlert but published December 1, 2022), which originated the news item, provides more detail, some of it disconcerting,

Now, a study led by Yoshiyuki Ueda at Kyoto University Institute for the Future of Human and Society [Japan], has shown AI’s potential in creating literary art such as haiku — the shortest poetic form in the world — rivaling that of humans without human help.

Ueda’s team compared AI-generated haiku without human intervention, also known as human out of the loop, or HOTL, with a contrasting method known as human in the loop, or HITL.

The project involved 385 participants, each of whom evaluated 40 haiku poems — 20 each of HITL and HOTL — plus 40 composed entirely by professional haiku writers.

“It was interesting that the evaluators found it challenging to distinguish between the haiku penned by humans and those generated by AI,” remarks Ueda.

From the results, HITL haiku received the most praise for their poetic qualities, whereas HOTL and human-only verses had similar scores.

“In addition, a phenomenon called algorithm aversion was observed among our evaluators. They were supposed to be unbiased but instead became influenced by a kind of reverse psychology,” explains the author.

“In other words, they tended to unconsciously give lower scores to those they felt were AI-generated.”

Ueda points out that his research has put a spotlight on algorithm aversion as a new approach to AI art.

“Our results suggest that the ability of AI in the field of haiku creation has taken a leap forward, entering the realm of collaborating with humans to produce more creative works. Realizing the existence of algorithmic aversion will lead people to re-evaluate their appreciation of AI art.”

Here’s a link to and a citation for the paper,

Does human–AI collaboration lead to more creative art? Aesthetic evaluation of human-made and AI-generated haiku poetry by Jimpei Hitsuwari, Yoshiyuki Ueda, Woojin Yun, Michio Nomura. Computers in Human Behavior Volume 139, February 2023, 107502 DOI: https://doi.org/10.1016/j.chb.2022.107502 Available online 4 October 2022, Version of Record 22 October 2022.

This paper is behind a paywall.

For those unfamiliar with Matsuo Bashō, he’s considered Japan’s most famous poet from the Edo period and Japan’s greatest master of haiku according to his Wikipedia entry. You can also find out more about Basho at the Poetry Foundation.

Periodic table of nanomaterials

This charming illustration is the only pictorial representation i’ve seen for Kyoto University’s (Japan) proposed periodic table of nanomaterials, (By the way, 2019 is UNESCO’s [United Nations Educational, Scientific and Cultural Organization] International Year of the Periodic Table of Elements, an event recognizing the table’s 150th anniversary. See my January 8, 2019 posting for information about more events.)

Caption: Molecules interact and align with each other as they self-assemble. This new simulation enables to find what molecules best interact with each other to build nanomaterials, such as materials that work as a nano electrical wire.
Credit Illustration by Izumi Mindy Takamiya

A July 23, 2018 news item on Nanowerk announces the new periodic table (Note: A link has been removed),

The approach was developed by Daniel Packwood of Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) and Taro Hitosugi of the Tokyo Institute of Technology (Nature Communications, “Materials informatics for self-assembly of functionalized organic precursors on metal surfaces”). It involves connecting the chemical properties of molecules with the nanostructures that form as a result of their interaction. A machine learning technique generates data that is then used to develop a diagram that categorizes different molecules according to the nano-sized shapes they form.

This approach could help materials scientists identify the appropriate molecules to use in order to synthesize target nanomaterials.

A July 23, 2018 Kyoto University press release on EurekAlert, which originated the news item, explains further about the computer simulations run by the scientists in pursuit of their specialized periodic table,

Fabricating nanomaterials using a bottom-up approach requires finding ‘precursor molecules’ that interact and align correctly with each other as they self-assemble. But it’s been a major challenge knowing how precursor molecules will interact and what shapes they will form.

Bottom-up fabrication of graphene nanoribbons is receiving much attention due to their potential use in electronics, tissue engineering, construction, and bio-imaging. One way to synthesise them is by using bianthracene precursor molecules that have bromine ‘functional’ groups attached to them. The bromine groups interact with a copper substrate to form nano-sized chains. When these chains are heated, they turn into graphene nanoribbons.

Packwood and Hitosugi tested their simulator using this method for building graphene nanoribbons.

Data was input into the model about the chemical properties of a variety of molecules that can be attached to bianthracene to ‘functionalize’ it and facilitate its interaction with copper. The data went through a series of processes that ultimately led to the formation of a ‘dendrogram’.

This showed that attaching hydrogen molecules to bianthracene led to the development of strong one-dimensional nano-chains. Fluorine, bromine, chlorine, amidogen, and vinyl functional groups led to the formation of moderately strong nano-chains. Trifluoromethyl and methyl functional groups led to the formation of weak one-dimensional islands of molecules, and hydroxide and aldehyde groups led to the formation of strong two-dimensional tile-shaped islands.

The information produced in the dendogram changed based on the temperature data provided. The above categories apply when the interactions are conducted at -73°C. The results changed with warmer temperatures. The researchers recommend applying the data at low temperatures where the effect of the functional groups’ chemical properties on nano-shapes are most clear.

The technique can be applied to other substrates and precursor molecules. The researchers describe their method as analogous to the periodic table of chemical elements, which groups atoms based on how they bond to each other. “However, in order to truly prove that the dendrograms or other informatics-based approaches can be as valuable to materials science as the periodic table, we must incorporate them in a real bottom-up nanomaterial fabrication experiment,” the researchers conclude in their study published in the journal xxx. “We are currently pursuing this direction in our laboratories.”

Here’s a link to and a citation for the paper,

Materials informatics for self-assembly of functionalized organic precursors on metal surfaces by Daniel M. Packwood & Taro Hitosugi. Nature Communicationsvolume 9, Article number: 2469 (2018)DOI: https://doi.org/10.1038/s41467-018-04940-z Published 25 June 2018

This paper is open access.

A potpourri of robot/AI stories: killers , kindergarten teachers, a Balenciaga-inspired AI fashion designer, a conversational android, and more

Following on my August 29, 2018 post (Sexbots, sexbot ethics, families, and marriage), I’m following up with a more general piece.

Robots, AI (artificial intelligence), and androids (humanoid robots), the terms can be confusing since there’s a tendency to use them interchangeably. Confession: I do it too, but, not this time. That said, I have multiple news bits.

Killer ‘bots and ethics

The U.S. military is already testing a Modular Advanced Armed Robotic System. Credit: Lance Cpl. Julien Rodarte, U.S. Marine Corps

That is a robot.

For the purposes of this posting, a robot is a piece of hardware which may or may not include an AI system and does not mimic a human or other biological organism such that you might, under circumstances, mistake the robot for a biological organism.

As for what precipitated this feature (in part), it seems there’s been a United Nations meeting in Geneva, Switzerland held from August 27 – 31, 2018 about war and the use of autonomous robots, i.e., robots equipped with AI systems and designed for independent action. BTW, it’s the not first meeting the UN has held on this topic.

Bonnie Docherty, lecturer on law and associate director of armed conflict and civilian protection, international human rights clinic, Harvard Law School, has written an August 21, 2018 essay on The Conversation (also on phys.org) describing the history and the current rules around the conduct of war, as well as, outlining the issues with the military use of autonomous robots (Note: Links have been removed),

When drafting a treaty on the laws of war at the end of the 19th century, diplomats could not foresee the future of weapons development. But they did adopt a legal and moral standard for judging new technology not covered by existing treaty language.

This standard, known as the Martens Clause, has survived generations of international humanitarian law and gained renewed relevance in a world where autonomous weapons are on the brink of making their own determinations about whom to shoot and when. The Martens Clause calls on countries not to use weapons that depart “from the principles of humanity and from the dictates of public conscience.”

I was the lead author of a new report by Human Rights Watch and the Harvard Law School International Human Rights Clinic that explains why fully autonomous weapons would run counter to the principles of humanity and the dictates of public conscience. We found that to comply with the Martens Clause, countries should adopt a treaty banning the development, production and use of these weapons.

Representatives of more than 70 nations will gather from August 27 to 31 [2018] at the United Nations in Geneva to debate how to address the problems with what they call lethal autonomous weapon systems. These countries, which are parties to the Convention on Conventional Weapons, have discussed the issue for five years. My co-authors and I believe it is time they took action and agreed to start negotiating a ban next year.

Docherty elaborates on her points (Note: A link has been removed),

The Martens Clause provides a baseline of protection for civilians and soldiers in the absence of specific treaty law. The clause also sets out a standard for evaluating new situations and technologies that were not previously envisioned.

Fully autonomous weapons, sometimes called “killer robots,” would select and engage targets without meaningful human control. They would be a dangerous step beyond current armed drones because there would be no human in the loop to determine when to fire and at what target. Although fully autonomous weapons do not yet exist, China, Israel, Russia, South Korea, the United Kingdom and the United States are all working to develop them. They argue that the technology would process information faster and keep soldiers off the battlefield.

The possibility that fully autonomous weapons could soon become a reality makes it imperative for those and other countries to apply the Martens Clause and assess whether the technology would offend basic humanity and the public conscience. Our analysis finds that fully autonomous weapons would fail the test on both counts.

I encourage you to read the essay in its entirety and for anyone who thinks the discussion about ethics and killer ‘bots is new or limited to military use, there’s my July 25, 2016 posting about police use of a robot in Dallas, Texas. (I imagine the discussion predates 2016 but that’s the earliest instance I have here.)

Teacher bots

Robots come in many forms and this one is on the humanoid end of the spectum,

Children watch a Keeko robot at the Yiswind Institute of Multicultural Education in Beijing, where the intelligent machines are telling stories and challenging kids with logic problems  [donwloaded from https://phys.org/news/2018-08-robot-teachers-invade-chinese-kindergartens.html]

Don’t those ‘eyes’ look almost heart-shaped? No wonder the kids love these robots, if an August  29, 2018 news item on phys.org can be believed,

The Chinese kindergarten children giggled as they worked to solve puzzles assigned by their new teaching assistant: a roundish, short educator with a screen for a face.

Just under 60 centimetres (two feet) high, the autonomous robot named Keeko has been a hit in several kindergartens, telling stories and challenging children with logic problems.

Round and white with a tubby body, the armless robot zips around on tiny wheels, its inbuilt cameras doubling up both as navigational sensors and a front-facing camera allowing users to record video journals.

In China, robots are being developed to deliver groceries, provide companionship to the elderly, dispense legal advice and now, as Keeko’s creators hope, join the ranks of educators.

At the Yiswind Institute of Multicultural Education on the outskirts of Beijing, the children have been tasked to help a prince find his way through a desert—by putting together square mats that represent a path taken by the robot—part storytelling and part problem-solving.

Each time they get an answer right, the device reacts with delight, its face flashing heart-shaped eyes.

“Education today is no longer a one-way street, where the teacher teaches and students just learn,” said Candy Xiong, a teacher trained in early childhood education who now works with Keeko Robot Xiamen Technology as a trainer.

“When children see Keeko with its round head and body, it looks adorable and children love it. So when they see Keeko, they almost instantly take to it,” she added.

Keeko robots have entered more than 600 kindergartens across the country with its makers hoping to expand into Greater China and Southeast Asia.

Beijing has invested money and manpower in developing artificial intelligence as part of its “Made in China 2025” plan, with a Chinese firm last year unveiling the country’s first human-like robot that can hold simple conversations and make facial expressions.

According to the International Federation of Robots, China has the world’s top industrial robot stock, with some 340,000 units in factories across the country engaged in manufacturing and the automotive industry.

Moving on from hardware/software to a software only story.

AI fashion designer better than Balenciaga?

Despite the title for Katharine Schwab’s August 22, 2018 article for Fast Company, I don’t think this AI designer is better than Balenciaga but from the pictures I’ve seen the designs are as good and it does present some intriguing possibilities courtesy of its neural network (Note: Links have been removed),

The AI, created by researcher Robbie Barat, has created an entire collection based on Balenciaga’s previous styles. There’s a fabulous pink and red gradient jumpsuit that wraps all the way around the model’s feet–like a onesie for fashionistas–paired with a dark slouchy coat. There’s a textural color-blocked dress, paired with aqua-green tights. And for menswear, there’s a multi-colored, shimmery button-up with skinny jeans and mismatched shoes. None of these looks would be out of place on the runway.

To create the styles, Barat collected images of Balenciaga’s designs via the designer’s lookbooks, ad campaigns, runway shows, and online catalog over the last two months, and then used them to train the pix2pix neural net. While some of the images closely resemble humans wearing fashionable clothes, many others are a bit off–some models are missing distinct limbs, and don’t get me started on how creepy [emphasis mine] their faces are. Even if the outfits aren’t quite ready to be fabricated, Barat thinks that designers could potentially use a tool like this to find inspiration. Because it’s not constrained by human taste, style, and history, the AI comes up with designs that may never occur to a person. “I love how the network doesn’t really understand or care about symmetry,” Barat writes on Twitter.

You can see the ‘creepy’ faces and some of the designs here,

Image: Robbie Barat

In contrast to the previous two stories, this all about algorithms, no machinery with independent movement (robot hardware) needed.

Conversational android: Erica

Hiroshi Ishiguro and his lifelike (definitely humanoid) robots have featured here many, many times before. The most recent posting is a March 27, 2017 posting about his and his android’s participation at the 2017 SXSW festival.

His latest work is featured in an August 21, 2018 news news item on ScienceDaily,

We’ve all tried talking with devices, and in some cases they talk back. But, it’s a far cry from having a conversation with a real person.

Now a research team from Kyoto University, Osaka University, and the Advanced Telecommunications Research Institute, or ATR, have significantly upgraded the interaction system for conversational android ERICA, giving her even greater dialog skills.

ERICA is an android created by Hiroshi Ishiguro of Osaka University and ATR, specifically designed for natural conversation through incorporation of human-like facial expressions and gestures. The research team demonstrated the updates during a symposium at the National Museum of Emerging Science in Tokyo.

Here’s the latest conversational android, Erica

Caption: The experimental set up when the subject (left) talks with ERICA (right) Credit: Kyoto University / Kawahara lab

An August 20, 2018 Kyoto University press release on EurekAlert, which originated the news item, offers more details,

When we talk to one another, it’s never a simple back and forward progression of information,” states Tatsuya Kawahara of Kyoto University’s Graduate School of Informatics, and an expert in speech and audio processing.

“Listening is active. We express agreement by nodding or saying ‘uh-huh’ to maintain the momentum of conversation. This is called ‘backchanneling’, and is something we wanted to implement with ERICA.”

The team also focused on developing a system for ‘attentive listening’. This is when a listener asks elaborating questions, or repeats the last word of the speaker’s sentence, allowing for more engaging dialogue.

Deploying a series of distance sensors, facial recognition cameras, and microphone arrays, the team began collecting data on parameters necessary for a fluid dialog between ERICA and a human subject.

“We looked at three qualities when studying backchanneling,” continues Kawahara. “These were: timing — when a response happens; lexical form — what is being said; and prosody, or how the response happens.”

Responses were generated through machine learning using a counseling dialogue corpus, resulting in dramatically improved dialog engagement. Testing in five-minute sessions with a human subject, ERICA demonstrated significantly more dynamic speaking skill, including the use of backchanneling, partial repeats, and statement assessments.

“Making a human-like conversational robot is a major challenge,” states Kawahara. “This project reveals how much complexity there is in listening, which we might consider mundane. We are getting closer to a day where a robot can pass a Total Turing Test.”

Erica seems to have been first introduced publicly in Spring 2017, from an April 2017 Erica: Man Made webpage on The Guardian website,

Erica is 23. She has a beautiful, neutral face and speaks with a synthesised voice. She has a degree of autonomy – but can’t move her hands yet. Hiroshi Ishiguro is her ‘father’ and the bad boy of Japanese robotics. Together they will redefine what it means to be human and reveal that the future is closer than we might think.

Hiroshi Ishiguro and his colleague Dylan Glas are interested in what makes a human. Erica is their latest creation – a semi-autonomous android, the product of the most funded scientific project in Japan. But these men regard themselves as artists more than scientists, and the Erica project – the result of a collaboration between Osaka and Kyoto universities and the Advanced Telecommunications Research Institute International – is a philosophical one as much as technological one.

Erica is interviewed about her hope and dreams – to be able to leave her room and to be able to move her arms and legs. She likes to chat with visitors and has one of the most advanced speech synthesis systems yet developed. Can she be regarded as being alive or as a comparable being to ourselves? Will she help us to understand ourselves and our interactions as humans better?

Erica and her creators are interviewed in the science fiction atmosphere of Ishiguro’s laboratory, and this film asks how we might form close relationships with robots in the future. Ishiguro thinks that for Japanese people especially, everything has a soul, whether human or not. If we don’t understand how human hearts, minds and personalities work, can we truly claim that humans have authenticity that machines don’t?

Ishiguro and Glas want to release Erica and her fellow robots into human society. Soon, Erica may be an essential part of our everyday life, as one of the new children of humanity.

Key credits

  • Director/Editor: Ilinca Calugareanu
  • Producer: Mara Adina
  • Executive producers for the Guardian: Charlie Phillips and Laurence Topham
  • This video is produced in collaboration with the Sundance Institute Short Documentary Fund supported by the John D and Catherine T MacArthur Foundation

You can also view the 14 min. film here.

Artworks generated by an AI system are to be sold at Christie’s auction house

KC Ifeanyi’s August 22, 2018 article for Fast Company may send a chill down some artists’ spines,

For the first time in its 252-year history, Christie’s will auction artwork generated by artificial intelligence.

Created by the French art collective Obvious, “Portrait of Edmond de Belamy” is part of a series of paintings of the fictional Belamy family that was created using a two-part algorithm. …

The portrait is estimated to sell anywhere between $7,000-$10,000, and Obvious says the proceeds will go toward furthering its algorithm.

… Famed collector Nicolas Laugero-Lasserre bought one of Obvious’s Belamy works in February, which could’ve been written off as a novel purchase where the story behind it is worth more than the piece itself. However, with validation from a storied auction house like Christie’s, AI art could shake the contemporary art scene.

“Edmond de Belamy” goes up for auction from October 23-25 [2018].

Jobs safe from automation? Are there any?

Michael Grothaus expresses more optimism about future job markets than I’m feeling in an August 30, 2018 article for Fast Company,

A 2017 McKinsey Global Institute study of 800 occupations across 46 countries found that by 2030, 800 million people will lose their jobs to automation. That’s one-fifth of the global workforce. A further one-third of the global workforce will need to retrain if they want to keep their current jobs as well. And looking at the effects of automation on American jobs alone, researchers from Oxford University found that “47 percent of U.S. workers have a high probability of seeing their jobs automated over the next 20 years.”

The good news is that while the above stats are rightly cause for concern, they also reveal that 53% of American jobs and four-fifths of global jobs are unlikely to be affected by advances in artificial intelligence and robotics. But just what are those fields? I spoke to three experts in artificial intelligence, robotics, and human productivity to get their automation-proof career advice.

Creatives

“Although I believe every single job can, and will, benefit from a level of AI or robotic influence, there are some roles that, in my view, will never be replaced by technology,” says Tom Pickersgill, …

Maintenance foreman

When running a production line, problems and bottlenecks are inevitable–and usually that’s a bad thing. But in this case, those unavoidable issues will save human jobs because their solutions will require human ingenuity, says Mark Williams, head of product at People First, …

Hairdressers

Mat Hunter, director of the Central Research Laboratory, a tech-focused co-working space and accelerator for tech startups, have seen startups trying to create all kinds of new technologies, which has given him insight into just what machines can and can’t pull off. It’s lead him to believe that jobs like the humble hairdresser are safer from automation than those of, says, accountancy.

Therapists and social workers

Another automation-proof career is likely to be one involved in helping people heal the mind, says Pickersgill. “People visit therapists because there is a need for emotional support and guidance. This can only be provided through real human interaction–by someone who can empathize and understand, and who can offer advice based on shared experiences, rather than just data-driven logic.”

Teachers

Teachers are so often the unsung heroes of our society. They are overworked and underpaid–yet charged with one of the most important tasks anyone can have: nurturing the growth of young people. The good news for teachers is that their jobs won’t be going anywhere.

Healthcare workers

Doctors and nurses will also likely never see their jobs taken by automation, says Williams. While automation will no doubt better enhance the treatments provided by doctors and nurses the fact of the matter is that robots aren’t going to outdo healthcare workers’ ability to connect with patients and make them feel understood the way a human can.

Caretakers

While humans might be fine with robots flipping their burgers and artificial intelligence managing their finances, being comfortable with a robot nannying your children or looking after your elderly mother is a much bigger ask. And that’s to say nothing of the fact that even today’s most advanced robots don’t have the physical dexterity to perform the movements and actions carers do every day.

Grothaus does offer a proviso in his conclusion: certain types of jobs are relatively safe until developers learn to replicate qualities such as empathy in robots/AI.

It’s very confusing

There’s so much news about robots, artificial intelligence, androids, and cyborgs that it’s hard to keep up with it let alone attempt to get a feeling for where all this might be headed. When you add the fact that the term robots/artificial inteligence are often used interchangeably and that the distinction between robots/androids/cyborgs is not always clear any attempts to peer into the future become even more challenging.

At this point I content myself with tracking the situation and finding definitions so I can better understand what I’m tracking. Carmen Wong’s August 23, 2018 posting on the Signals blog published by Canada’s Centre for Commercialization of Regenerative Medicine (CCRM) offers some useful definitions in the context of an article about the use of artificial intelligence in the life sciences, particularly in Canada (Note: Links have been removed),

Artificial intelligence (AI). Machine learning. To most people, these are just buzzwords and synonymous. Whether or not we fully understand what both are, they are slowly integrating into our everyday lives. Virtual assistants such as Siri? AI is at work. The personalized ads you see when you are browsing on the web or movie recommendations provided on Netflix? Thank AI for that too.

AI is defined as machines having intelligence that imitates human behaviour such as learning, planning and problem solving. A process used to achieve AI is called machine learning, where a computer uses lots of data to “train” or “teach” itself, without human intervention, to accomplish a pre-determined task. Essentially, the computer keeps on modifying its algorithm based on the information provided to get to the desired goal.

Another term you may have heard of is deep learning. Deep learning is a particular type of machine learning where algorithms are set up like the structure and function of human brains. It is similar to a network of brain cells interconnecting with each other.

Toronto has seen its fair share of media-worthy AI activity. The Government of Canada, Government of Ontario, industry and multiple universities came together in March 2018 to launch the Vector Institute, with the goal of using AI to promote economic growth and improve the lives of Canadians. In May, Samsung opened its AI Centre in the MaRS Discovery District, joining a network of Samsung centres located in California, United Kingdom and Russia.

There has been a boom in AI companies over the past few years, which span a variety of industries. This year’s ranking of the top 100 most promising private AI companies covers 25 fields with cybersecurity, enterprise and robotics being the hot focus areas.

Wong goes on to explore AI deployment in the life sciences and concludes that human scientists and doctors will still be needed although she does note this in closing (Note: A link has been removed),

More importantly, empathy and support from a fellow human being could never be fully replaced by a machine (could it?), but maybe this will change in the future. We will just have to wait and see.

Artificial empathy is the term used in Lisa Morgan’s April 25, 2018 article for Information Week which unfortunately does not include any links to actual projects or researchers working on artificial empathy. Instead, the article is focused on how business interests and marketers would like to see it employed. FWIW, I have found a few references: (1) Artificial empathy Wikipedia essay (look for the references at the end of the essay for more) and (2) this open access article: Towards Artificial Empathy; How Can Artificial Empathy Follow the Developmental Pathway of Natural Empathy? by Minoru Asada.

Please let me know in the comments if you should have an insights on the matter in the comments section of this blog.

A new platform for culturing stem cells: a Multiplexed Artificial Cellular Microenvironment array

Japanese scientists have developed a more precise method for culturing stem cells according to a March 14, 2017 news item on Nanowerk,

A team of researchers in Japan has developed a new platform for culturing human pluripotent stem cells that provides far more control of culture conditions than previous tools by using micro and nanotechnologies.

The Multiplexed Artificial Cellular Microenvironment (MACME) array places nanofibres, mimicking cellular matrices, into fluid-filled micro-chambers of precise sizes, which mimic extracellular environments.

Caption: The Multiplexed Artificial Cellular Microenvironment (MACME) array, consisted with a microfluidic structure and nanofibre array for mimicking cellular microenvironments. Credit: Kyoto University iCeMS

A March 17, 2017 Kyoto University press release (also on EurekAlert), which originated the news item, explains the research in more detail,

Human pluripotent stems cells (hPSCs) hold great promise for tissue engineering, regenerative medicine and cell-based therapies because they can become any type of cell. The environment surrounding the cells plays a major role in determining what tissues they become, if they replicate into more cells, or die. However, understanding these interactions has been difficult because researchers have lacked tools that work on the appropriate scale.

Often, stem cells are cultured in a cell culture medium in small petri dishes. While factors such as medium pH levels and nutrients can be controlled, the artificial set up is on the macroscopic scale and does not allow for precise control of the physical environment surrounding the cells.

The MACME array miniaturizes this set up, culturing stem cells in rows of micro-chambers of cell culture medium. It also takes it a step further by placing nanofibers in these chambers to mimic the structures found around cells.

Led by Ken-ichiro Kamei of Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS), the team tested a variety of nanofiber materials and densities, micro-chamber heights and initial stem cell densities to determine the best combination that encourages human pluripotent stem cells to replicate.

They stained the cells with several fluorescent markers and used a microscope to see if the cells died, replicated or differentiated into tissues.

Their analysis revealed that gelatin nanofibers and medium-sized chambers that create medium seed cell density provided the best environment for the stem cells to continue to multiply. The quantity and density of neighboring cells strongly influences cell survival.

The array is an “optimal and powerful approach for understanding how environmental cues regulate cellular functions,” the researchers conclude in a recently published paper in the journal Small.

This array appears to be the first time multiple kinds of extracellular environments can be mounted onto a single device, making it much easier to compare how different environments influence cells.

The MACME array could substantially reduce experiment costs compared to conventional tools, in part because it is low volume and requires less cell culture medium. The array does not require any special equipment and is compatible with both commonly used laboratory pipettes and automated pipette systems for performing high-throughput screening.

Here’s a link to and a citation for the paper,

Microfluidic-Nanofiber Hybrid Array for Screening of Cellular Microenvironments by Ken-ichiro Kamei, Yasumasa Mashimo, Momoko Yoshioka, Yumie Tokunaga, Christopher Fockenberg, Shiho Terada, Yoshie Koyama, Minako Nakajima, Teiko Shibata-Seki, Li Liu, Toshihiro Akaike, Eiry Kobatake, Siew-Eng How, Motonari Uesugi, and Yong Chen. Small DOI: 10.1002/smll.201603104 Version of Record online: 8 MAR 2017

© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

This paper is behind a paywall.

Matrix of gelatin nanofibres for culturing large quantities of human stem cells

A Feb. 14, 2017 news item on ScienceDaily describes work that may have a big influence on stem cell production,

A new nanofiber-on-microfiber matrix could help produce more and better quality stem cells for disease treatment and regenerative therapies.

A matrix made of gelatin nanofibers on a synthetic polymer microfiber mesh may provide a better way to culture large quantities of healthy human stem cells.

Developed by a team of researchers led by Ken-ichiro Kamei of Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS), the ‘fiber-on-fiber’ (FF) matrix improves on currently available stem cell culturing techniques.

A Feb. 14/15, 2017 Kyoto University press release (also on EurekAlert), which originated the news item, explains why scientists are trying to find a new way to culture stem cells,

Researchers have been developing 3D culturing systems to allow human pluripotent stem cells (hPSCs) to grow and interact with their surroundings in all three dimensions, as they would inside the human body, rather than in two dimensions, like they do in a petri dish.

Pluripotent stem cells have the ability to differentiate into any type of adult cell and have huge potential for tissue regeneration therapies, treating diseases, and for research purposes.

Most currently reported 3D culturing systems have limitations, and result in low quantities and quality of cultured cells.

Kamei and his colleagues fabricated gelatin nanofibers onto a microfiber sheet made of synthetic, biodegradable polyglycolic acid. Human embryonic stem cells were then seeded onto the matrix in a cell culture medium.

The FF matrix allowed easy exchange of growth factors and supplements from the culture medium to the cells. Also, the stem cells adhered well to the matrix, resulting in robust cell growth: after four days of culture, more than 95% of the cells grew and formed colonies.

The team also scaled up the process by designing a gas-permeable cell culture bag in which multiple cell-loaded, folded FF matrices were placed. The system was designed so that minimal changes were needed to the internal environment, reducing the amount of stress placed on the cells. This newly developed system yielded a larger number of cells compared to conventional 2D and 3D culture methods.

“Our method offers an efficient way to expand hPSCs of high quality within a shorter term,” write the researchers in their study published in the journal Biomaterials. Also, because the use of the FF matrix is not limited to a specific type of culture container, it allows for scaling up production without loss of cell functions. “Additionally, as nanofiber matrices are advantageous for culturing other adherent cells, including hPSC-derived differentiated cells, FF matrix might be applicable to the large-scale production of differentiated functional cells for various applications,” the researchers conclude.

Human stem cells that grew on the ‘fiber-on-fiber’ culturing system

Here’s a link to and a citation for the paper,

Nano-on-micro fibrous extracellular matrices for scalable expansion of human ES/iPS cells by Li Liu, Ken-ichiro Kamei, Momoko Yoshioka, Minako Nakajima, Junjun Li, Nanae Fujimoto, Shiho Terada, Yumie Tokunaga, Yoshie Koyama, Hideki Sato, Kouichi Hasegawa. Biomaterials Volume 124, April 2017, Pages 47–54  http://dx.doi.org/10.1016/j.biomaterials.2017.01.039

This paper is behind a paywall.

Watching artificial nanofibres self-sort in real-time

A May 31, 2016 news item on phys.org describes research on self-assembling fibres at Kyoto University (Japan) by referencing the ancient Greek mythological figure, Psyche,

The Greek goddess Psyche borrowed help from ants to sort a room full of different grains. Cells, on the other hand, do something similar without Olympian assistance, as they organize molecules into robust, functional fibers. Now scientists are able to see self-sorting phenomena happen in real time with artificial molecules.

The achievement, reported in Nature Chemistry, elucidates how two different types of nanofibers sort themselves into organized structures under artificial conditions.

“Basic cellular structures, such as actin filaments, come into being through the autonomous self-sorting of individual molecules, even though a tremendous variety of proteins and small molecules are present inside the cell,” says lead author Hajime Shigemitsu, a researcher in Itaru Hamachi’s lab at Kyoto University.

A May 30, 2016 Kyoto University news release (also on EurekAlert), which originated the news item, expands on the theme,

“Imagine a box filled with an assortment of building blocks — it’s as if the same type of blocks started sorting themselves into neat bundles all on their own. In living cells, such phenomena always happen, enabling accurate self-assembling of proteins, which is essential for cell functions.”

“If we are able to control self-sorting with artificial molecules, we can work toward developing intelligent, next-generation biomimics that possess the flexibility and diversity of functions that exist in a living cell.”

Study co-author Ryou Kubota explains that previous studies have already made artificial molecules build themselves into fibers — but only when there was one type of molecule around. Having a jumble of types, on the other hand, made the molecules confused.

“The difficulty in inducing self-assembly with artificial molecules is that they don’t recognize the same type of molecule, unlike molecules in the natural world. Different types of artificial molecules interact with each other and make an unsorted cluster.”

From a database of structural analyses, Hamachi and colleagues discovered a combination of nanofibers — namely a peptide-based and lipid-based hydrogelator — that would make sorted fibers without mixing with the other. They then tethered the fibers with fluorescent probes; with a type of microscope typically used in cell imaging, the team was able to observe directly and in real-time how the artificial molecules sorted themselves.

“Ultimately, this finding could help develop new materials that respond dynamically to different environments and stimuli,” elaborates Hamachi. “This insight is not only useful for materials science, but may also provide useful clues for understanding self-organization in cells.”

Here’s a link to and a citation for the paper,

In situ real-time imaging of self-sorted supramolecular nanofibres by Shoji Onogi, Hajime Shigemitsu, Tatsuyuki Yoshii, Tatsuya Tanida, Masato Ikeda, Ryou Kubota, & Itaru Hamachi. Nature Chemistry (2016) doi:10.1038/nchem.2526 Published online 30 May 2016

This paper is behind a paywall bu the researchers have made a video of the self-sorting proteins freely available,

Japanese researchers note the emergence of the ‘Devil’s staircase’

I wanted to know why it’s called the ‘Devil’s staircase’ and this is what I found. According to Wikipedia there are several of them,

I gather the scientists are referring to the Cantor function (mathematics), Note: Links have been removed,

In mathematics, the Cantor function is an example of a function that is continuous, but not absolutely continuous. It is also referred to as the Cantor ternary function, the Lebesgue function, Lebesgue’s singular function, the Cantor-Vitali function, the Devil’s staircase,[1] the Cantor staircase function,[2] and the Cantor-Lebesgue function.[3]

Here’s a diagram illustrating the Cantor function (from the Wikipedia entry),

CC BY-SA 3.0 File:CantorEscalier.svg Uploaded by Theon Created: January 24, 2009

CC BY-SA 3.0
File:CantorEscalier.svg
Uploaded by Theon
Created: January 24, 2009

As for this latest ‘Devil’s staircase’, a June 17, 2015 news item on Nanowerk announces the research (Note: A link has been removed),

Researchers at the University of Tokyo have revealed a novel magnetic structure named the “Devil’s staircase” in cobalt oxides using soft X-rays (“Observation of a Devil’s Staircase in the Novel Spin-Valve System SrCo6O11“). This is an important result since the researchers succeeded in determining the detailed magnetic structure of a very small single crystal invisible to the human eye.

A June 17, 2015 University of Tokyo press release, which originated the news item on Nanowerk, describes why this research is now possible and the impact it could have,

Recent remarkable progress in resonant soft x-ray diffraction performed in synchrotron facilities has made it possible to determine spin ordering (magnetic structure) in small-volume samples including thin films and nanostructures, and thus is expected to lead not only to advances in materials science but also application to spintronics, a technology which is expected to form the basis of future electronic devices. Cobalt oxide is known as one material that is suitable for spintronics applications, but its magnetic structure was not fully understood.

The research group of Associate Professor Hiroki Wada at the University of Tokyo Institute for Solid State Physics, together with the researchers at Kyoto University and in Germany, performed a resonant soft X-ray diffraction study of cobalt (Co) oxides in the synchrotron facility BESSY II in Germany. They observed all the spin orderings which are theoretically possible and determined how these orderings change with the application of magnetic fields. The plateau-like behavior of magnetic structure as a function of magnetic field is called the “Devil’s staircase,” and is the first such discovery in spin systems in 3D transition metal oxides including cobalt, iron, manganese.

By further resonant soft X-ray diffraction studies, one can expect to find similar “Devil’s staircase” behavior in other materials. By increasing the spatial resolution of microscopic observation of the “Devil’s staircase” may lead to the development of novel types of spintronics materials.

Here’s an example of the ‘cobalt’ Devil’s staircase,

The magnetic structure that gives rise to the Devil's Staircase Magnetization (vertical axis) of cobalt oxide shows plateau like behaviors as a function of the externally-applied magnetic field (horizontal axis). The researchers succeeded in determining the magnetic structures which create such plateaus. Red and blue arrows indicate spin direction. © 2015 Hiroki Wadati.

The magnetic structure that gives rise to the Devil’s Staircase
Magnetization (vertical axis) of cobalt oxide shows plateau like behaviors as a function of the externally-applied magnetic field (horizontal axis). The researchers succeeded in determining the magnetic structures which create such plateaus. Red and blue arrows indicate spin direction.
© 2015 Hiroki Wadati.

Here’s a link to and a citation for the paper,

Observation of a Devil’s Staircase in the Novel Spin-Valve System SrCo6O11 by T. Matsuda, S. Partzsch, T. Tsuyama, E. Schierle, E. Weschke, J. Geck, T. Saito, S. Ishiwata, Y. Tokura, and H. Wadati. Phys. Rev. Lett. 114, 236403 – Published 11 June 2015 (paper: Vol. 114, Iss. 23 — 12 June 2015)  DOI: 10.1103/PhysRevLett.114.236403

This paper is behind a paywall.

Nano and stem cell differentiation at Rutgers University (US)

A Nov. 14, 2014 news item on Azonano features a nanoparticle-based platform for differentiating stem cells,

Rutgers University Chemistry Associate Professor Ki-Bum Lee has developed patent-pending technology that may overcome one of the critical barriers to harnessing the full therapeutic potential of stem cells.

A Nov. 1, 2104 Rutgers University news release, which originated the news item, describes the challenge in more detail,

One of the major challenges facing researchers interested in regenerating cells and growing new tissue to treat debilitating injuries and diseases such as Parkinson’s disease, heart disease, and spinal cord trauma, is creating an easy, effective, and non-toxic methodology to control differentiation into specific cell lineages. Lee and colleagues at Rutgers and Kyoto University in Japan have invented a platform they call NanoScript, an important breakthrough for researchers in the area of gene expression. Gene expression is the way information encoded in a gene is used to direct the assembly of a protein molecule, which is integral to the process of tissue development through stem cell therapeutics.

Stem cells hold great promise for a wide range of medical therapeutics as they have the ability to grow tissue throughout the body. In many tissues, stem cells have an almost limitless ability to divide and replenish other cells, serving as an internal repair system.

Transcription factor (TF) proteins are master regulators of gene expression. TF proteins play a pivotal role in regulating stem cell differentiation. Although some have tried to make synthetic molecules that perform the functions of natural transcription factors, NanoScript is the first nanomaterial TF protein that can interact with endogenous DNA. …

“Our motivation was to develop a highly robust, efficient nanoparticle-based platform that can regulate gene expression and eventually stem cell differentiation,” said Lee, who leads a Rutgers research group primarily focused on developing and integrating nanotechnology with chemical biology to modulate signaling pathways in cancer and stem cells. “Because NanoScript is a functional replica of TF proteins and a tunable gene-regulating platform, it has great potential to do exactly that. The field of stem cell biology now has another platform to regulate differentiation while the field of nanotechnology has demonstrated for the first time that we can regulate gene expression at the transcriptional level.”

Here’s an image illustrating NanoScript and gold nanoparticles,

Courtesy Rutgers University

Courtesy Rutgers University

The news release goes on to describe the platform’s use of gold nanoparticles,

NanoScript was constructed by tethering functional peptides and small molecules called synthetic transcription factors, which mimic the individual TF domains, onto gold nanoparticles.

“NanoScript localizes within the nucleus and initiates transcription of a reporter plasmid by up to 30-fold,” said Sahishnu Patel, Rutgers Chemistry graduate student and co-author of the ACS Nano publication. “NanoScript can effectively transcribe targeted genes on endogenous DNA in a nonviral manner.”

Lee said the next step for his research is to study what happens to the gold nanoparticles after NanoScript is utilized, to ensure no toxic effects arise, and to ensure the effectiveness of NanoScript over long periods of time.

“Due to the unique tunable properties of NanoScript, we are highly confident this platform not only will serve as a desirable alternative to conventional gene-regulating methods,” Lee said, “but also has direct employment for applications involving gene manipulation such as stem cell differentiation, cancer therapy, and cellular reprogramming. Our research will continue to evaluate the long-term implications for the technology.”

Lee, originally from South Korea, joined the Rutgers faculty in 2008 and has earned many honors including the NIH Director’s New Innovator Award. Lee received his Ph.D. in Chemistry from Northwestern University where he studied with Professor Chad. A. Mirkin, a pioneer in the coupling of nanotechnology and biomolecules. Lee completed his postdoctoral training at The Scripps Research Institute with Professor Peter G. Schultz. Lee has served as a Visiting Scholar at both Princeton University and UCLA Medical School.

The primary interest of Lee’s group is to develop and integrate nanotechnologies and chemical functional genomics to modulate signaling pathways in mammalian cells towards specific cell lineages or behaviors. He has published more than 50 articles and filed for 17 corresponding patents.

Here’s a link to and a citation for the paper,

NanoScript: A Nanoparticle-Based Artificial Transcription Factor for Effective Gene Regulation by Sahishnu Patel, Dongju Jung, Perry T. Yin, Peter Carlton, Makoto Yamamoto, Toshikazu Bando, Hiroshi Sugiyama, and Ki-Bum Lee. ACS Nano, 2014, 8 (9), pp 8959–8967 DOI: 10.1021/nn501589f Publication Date (Web): August 18, 2014
Copyright © 2014 American Chemical Society

This paper is behind a paywall.

You say nanocrystalline cellulose, I say cellulose nanocrystals; CelluForce at Japan conference and at UK conference

In reading the Oct. 14, 2012 news release from CelluForce about its presence at conferences in Japan and in the UK, I was interested to note the terminology being used,

CelluForce, the world leader in the commercial development of NanoCrystalline Cellulose (NCC), also referred to as Cellulose Nanocrystals (CNC),[emphases mine] is participating in two  upcoming industry conferences:  the ‘Nanocellulose Summit 2012’ in Kyoto, Japan on October 15, 2012, and ‘Investing in Cellulose 2012’, in London, UK, on November 5, 2012.

All of the materials from Canadian companies and not-for-profits have used the term nanocrystalline cellulose (NCC) exclusively, until now. I gather there’ve been some international discussions regarding terminology and that the term cellulose nanocrystals (CNC) is, at the least, a synonym if not the preferred term.

Here’s more about the conference in Japan (from the CelluForce news release),

The 209th Symposium on Sustainable Humanosphere: Nanocellulose Summit 2012’ welcomes the world’s top scientists and large research project leaders involved with nanocellulose to present on each country’s current status and prospects concerning nanocellulose research and industrialization.

What:                  CelluForce – What do we do?

Who:                    Richard Berry, Vice President and Chief  Technology Officer, CelluForce

When:                 Monday, October 15, 2012, 4 p.m. JST

Where:                 Kyoto Terrsa Venue, Shinmachi Kujo Minami-ku,
Kyoto, Japan (Kyoto Citizen’s Amenity Plaza)

I found out a little more about the conference Dr. Richard Berry will be attending on the Nanocellulose Summit 2012 webpage on the Kyoto University website,

The world’s top scientists and large research project leaders involved with nanocellulose (cellulose nanofiber (CNF) [sic] and cellulose nanocrystal (CNC or NCC) ) brought together. They will talk about each country’s current status and prospects concerning nanocellulose research and industrialization.

You can find more details, including the agenda, on the conference webpage.

Here’s more about the investment-oriented conference taking place in the UK,

In its second edition, ‘Investing in Cellulose 2012’ is a global conference on specialty cellulose, organized by CelCo. The company focuses primarily on the specialty cellulose business including the organization of cellulose training courses as well as advisory and consultancy to the industry.

What:                  Nanocrystalline technologies: Bringing Innovation to the Market

Who:                    Jean Moreau, President and CEO, CelluForce

When:                 Monday, November 5, 2012, 2:30 p.m. BST

Where:                The Royal Horseguards Hotel, 2 Whitehall Court Whitehall, London SW1A 2EJ, United Kingdom

I have found an ‘Investing in Cellulose 2012‘ conference webpage (of sorts) on the CelCo website (Note: I have removed some of the formatting),

Based on the success of 2011 specialty cellulose conference and encouraged by a 92% return intention response we are pleased to announce that Investing in Cellulose -2012 Conference will take place in London on November 5th.

A cocktail will kick off the event the preceding night and close around 18:00 of November 5th.

So please SAVE THE DATE in your calendar and contact us HERE

 We have taken into account your wishes and suggestions for this second year event and some of the changes will include:

  • Antitrust lawyer attending meeting allowing larger participation esp. from USA.
  • New topics to allow ether and viscose market to be better covered. Technology section during the day.
  • Seat in lunch accommodations and air condition.
  • Larger china representation.
  • More downstream value chain participation.

We will share later this year the Agenda but feel free to let us know if there were any particular topics you would like us to cover or you would like to present.

The most I could find out about the UK conference organizer is that  Celco Cellulose Consulting is a Swiss company founded by two partners.