Monthly Archives: June 2017

Refining metals more sustainably

We don’t just extract and refine metals from the earth, increasingly, we extract and refine them from consumer goods. Researchers from McGill University (Montréal, Québec, Canada) have devised a ‘greener’ technique to do this. From a June 7, 2017 McGill University news release (received via email and also on EurekAlert),

A team of chemists in Canada has developed a way to process metals without using toxic solvents and reagents.

The system, which also consumes far less energy than conventional techniques, could greatly shrink the environmental impact of producing metals from raw materials or from post-consumer electronics.

“At a time when natural deposits of metals are on the decline, there is a great deal of interest in improving the efficiency of metal refinement and recycling, but few disruptive technologies are being put forth,” says Jean-Philip Lumb, an associate professor in McGill University’s Department of Chemistry. “That’s what makes our advance so important.”

The discovery stems from a collaboration between Lumb and Tomislav Friscic at McGill in Montreal, and Kim Baines of Western University in London, Ont. In an article published recently in Science Advances, the researchers outline an approach that uses organic molecules, instead of chlorine and hydrochloric acid, to help purify germanium, a metal used widely in electronic devices. Laboratory experiments by the researchers have shown that the same technique can be used with other metals, including zinc, copper, manganese and cobalt.

The research could mark an important milestone for the “green chemistry” movement, which seeks to replace toxic reagents used in conventional industrial manufacturing with more environmentally friendly alternatives. Most advances in this area have involved organic chemistry – the synthesis of carbon-based compounds used in pharmaceuticals and plastics, for example.

“Applications of green chemistry lag far behind in the area of metals,” Lumb says. “Yet metals are just as important for sustainability as any organic compound. For example, electronic devices require numerous metals to function.”

Taking a page from biology

There is no single ore rich in germanium, so it is generally obtained from mining operations as a minor component in a mixture with many other materials. Through a series of processes, that blend of matter can be reduced to germanium and zinc.

“Currently, in order to isolate germanium from zinc, it’s a pretty nasty process,” Baines explains. The new approach developed by the McGill and Western chemists “enables you to get germanium from zinc, without those nasty processes.”

To accomplish this, the researchers took a page from biology. Lumb’s lab for years has conducted research into the chemistry of melanin, the molecule in human tissue that gives skin and hair their color. Melanin also has the ability to bind to metals. “We asked the question: ‘Here’s this biomaterial with exquisite function, would it be possible to use it as a blueprint for new, more efficient technologies?'”

The scientists teamed up to synthesize a molecule that mimics some of the qualities of melanin. In particular, this “organic co-factor” acts as a mediator that helps to extract germanium at room temperature, without using solvents.

Next step: industrial scale

The system also taps into Friscic’s expertise in mechanochemistry, an emerging branch of chemistry that relies on mechanical force – rather than solvents and heat – to promote chemical reactions. Milling jars containing stainless-steel balls are shaken at high speeds to help purify the metal.

“This shows how collaborations naturally can lead to sustainability-oriented innovation,” Friscic says. “Combining elegant new chemistry with solvent-free mechanochemical techniques led us to a process that is cleaner by virtue of circumventing chlorine-based processing, but also eliminates the generation of toxic solvent waste”

The next step in developing the technology will be to show that it can be deployed economically on industrial scales, for a range of metals.

“There’s a tremendous amount of work that needs to be done to get from where we are now to where we need to go,” Lumb says. “But the platform works on many different kinds of metals and metal oxides, and we think that it could become a technology adopted by industry. We are looking for stakeholders with whom we can partner to move this technology forward.”

Here’s a link to and a citation for the paper,

A chlorine-free protocol for processing germanium by Martin Glavinovic, Michael Krause, Linju Yang, John A. McLeod, Lijia Liu, Kim M. Baines, Tomislav Friščić, and Jean-Philip Lumb. Science Advances 05 May 2017: Vol. 3, no. 5, e1700149 DOI: 10.1126/sciadv.1700149

This paper is open access.

ETA June 9, 2017 at 1700 hours PDT: I have to give them marks for creativity. Here’s the image being used to illustrate the work,

Caption: Strategy for reducing the environmental impact of a refining process: replace hazardous chemicals with more benign and recyclable compounds. Credit: Michael J. Krause (Western University)

4D printing, what is that?

According to an April 12, 2017 news item on ScienceDaily, shapeshifting in response to environmental stimuli is the fourth dimension (I have a link to a posting about 4D printing with another fourth dimension),

A team of researchers from Georgia Institute of Technology and two other institutions has developed a new 3-D printing method to create objects that can permanently transform into a range of different shapes in response to heat.

The team, which included researchers from the Singapore University of Technology and Design (SUTD) and Xi’an Jiaotong University in China, created the objects by printing layers of shape memory polymers with each layer designed to respond differently when exposed to heat.

“This new approach significantly simplifies and increases the potential of 4-D printing by incorporating the mechanical programming post-processing step directly into the 3-D printing process,” said Jerry Qi, a professor in the George W. Woodruff School of Mechanical Engineering at Georgia Tech. “This allows high-resolution 3-D printed components to be designed by computer simulation, 3-D printed, and then directly and rapidly transformed into new permanent configurations by simply heating.”

The research was reported April 12 [2017] in the journal Science Advances, a publication of the American Association for the Advancement of Science. The work is funded by the U.S. Air Force Office of Scientific Research, the U.S. National Science Foundation and the Singapore National Research Foundation through the SUTD DManD Centre.

An April 12, 2017 Singapore University of Technology and Design (SUTD) press release on EurekAlert provides more detail,

4D printing is an emerging technology that allows a 3D-printed component to transform its structure by exposing it to heat, light, humidity, or other environmental stimuli. This technology extends the shape creation process beyond 3D printing, resulting in additional design flexibility that can lead to new types of products which can adjust its functionality in response to the environment, in a pre-programmed manner. However, 4D printing generally involves complex and time-consuming post-processing steps to mechanically programme the component. Furthermore, the materials are often limited to soft polymers, which limit their applicability in structural scenarios.

A group of researchers from the SUTD, Georgia Institute of Technology, Xi’an Jiaotong University and Zhejiang University has introduced an approach that significantly simplifies and increases the potential of 4D printing by incorporating the mechanical programming post-processing step directly into the 3D printing process. This allows high-resolution 3D-printed components to be designed by computer simulation, 3D printed, and then directly and rapidly transformed into new permanent configurations by using heat. This approach can help save printing time and materials used by up to 90%, while completely eliminating the time-consuming mechanical programming process from the design and manufacturing workflow.

“Our approach involves printing composite materials where at room temperature one material is soft but can be programmed to contain internal stress, and the other material is stiff,” said Dr. Zhen Ding of SUTD. “We use computational simulations to design composite components where the stiff material has a shape and size that prevents the release of the programmed internal stress from the soft material after 3D printing. Upon heating, the stiff material softens and allows the soft material to release its stress. This results in a change – often dramatic – in the product shape.” This new shape is fixed when the product is cooled, with good mechanical stiffness. The research demonstrated many interesting shape changing parts, including a lattice that can expand by almost 8 times when heated.

This new shape becomes permanent and the composite material will not return to its original 3D-printed shape, upon further heating or cooling. “This is because of the shape memory effect,” said Prof. H. Jerry Qi of Georgia Tech. “In the two-material composite design, the stiff material exhibits shape memory, which helps lock the transformed shape into a permanent one. Additionally, the printed structure also exhibits the shape memory effect, i.e. it can then be programmed into further arbitrary shapes that can always be recovered to its new permanent shape, but not its 3D-printed shape.”

Said SUTD’s Prof. Martin Dunn, “The key advance of this work, is a 4D printing method that is dramatically simplified and allows the creation of high-resolution complex 3D reprogrammable products; it promises to enable myriad applications across biomedical devices, 3D electronics, and consumer products. It even opens the door to a new paradigm in product design, where components are designed from the onset to inhabit multiple configurations during service.”

Here’s a video,


Uploaded on Apr 17, 2017

A research team led by the Singapore University of Technology and Design’s (SUTD) Associate Provost of Research, Professor Martin Dunn, has come up with a new and simplified 4D printing method that uses a 3D printer to rapidly create 3D objects, which can permanently transform into a range of different shapes in response to heat.

Here’s a link to and a citation for the paper,

Direct 4D printing via active composite materials by Zhen Ding, Chao Yuan, Xirui Peng, Tiejun Wang, H. Jerry Qi, and Martin L. Dunn. Science Advances  12 Apr 2017: Vol. 3, no. 4, e1602890 DOI: 10.1126/sciadv.1602890

This paper is open access.

Here is a link to a post about another 4th dimension, time,

4D printing: a hydrogel orchid (Jan. 28, 2016)

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report): 3 of 3

This is the final commentary on the report titled,(INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research). Part 1 of my commentary having provided some introductory material and first thoughts about the report, Part 2 offering more detailed thoughts; this part singles out ‘special cases’, sums up* my thoughts (circling back to ideas introduced in the first part), and offers link to other commentaries.

Special cases

Not all of the science funding in Canada is funneled through the four agencies designed for that purpose, (The Natural Sciences and Engineering Research Council (NSERC), Social Sciences and Humanities Research Council (SSHRC), Canadian Institutes of Health Research (CIHR) are known collectively as the tri-council funding agencies and are focused on disbursement of research funds received from the federal government. The fourth ‘pillar’ agency, the Canada Foundation for Innovation (CFI) is focused on funding for infrastructure and, technically speaking, is a 3rd party organization along with MITACS, CANARIE, the Perimeter Institute, and others.

In any event, there are also major research facilities and science initiatives which may receive direct funding from the federal government bypassing the funding agencies and, it would seem, peer review. For example, I featured this in my April 28, 2015 posting about the 2015 federal budget,

The $45 million announced for TRIUMF will support the laboratory’s role in accelerating science in Canada, an important investment in discovery research.

While the news about the CFI seems to have delighted a number of observers, it should be noted (as per Woodgett’s piece) that the $1.3B is to be paid out over six years ($220M per year, more or less) and the money won’t be disbursed until the 2017/18 fiscal year. As for the $45M designated for TRIUMF (Canada’s National Laboratory for Particle and Nuclear Physics), this is exciting news for the lab which seems to have bypassed the usual channels, as it has before, to receive its funding directly from the federal government. [emphases mine]

The Naylor report made this recommendation for Canada’s major research facilities, (MRF)

We heard from many who recommended that the federal government should manage its investments in “Big Science” in a more coordinated manner, with a cradle-to-grave perspective. The Panel agrees. Consistent with NACRI’s overall mandate, it should work closely with the CSA [Chief Science Advisor] in establishing a Standing Committee on Major Research Facilities (MRFs).

CFI defines a national research facility in the following way:

We define a national research facility as one that addresses the needs of a community of Canadian researchers representing a critical mass of users distributed across the country. This is done by providing shared access to substantial and advanced specialized equipment, services, resources, and scientific and technical personnel. The facility supports leading-edge research and technology development, and promotes the mobilization of knowledge and transfer of technology to society. A national research facility requires resource commitments well beyond the capacity of any one institution. A national research facility, whether single-sited, distributed or virtual, is specifically identified or recognized as serving pan-Canadian needs and its governance and management structures reflect this mandate.8

We accept this definition as appropriate for national research facilities to be considered by the Standing Committee on MRFs, but add that the committee should:

• define a capital investment or operating cost level above which such facilities are considered “major” and thus require oversight by this committee (e.g., defined so as to include the national MRFs proposed in Section 6.3: Compute Canada, Canadian Light Source, Canada’s National Design Network, Canadian Research Icebreaker Amundsen, International Vaccine Centre, Ocean Networks Canada, Ocean Tracking Network, and SNOLAB plus the TRIUMF facility); and

• consider international MRFs in which Canada has a significant role, such as astronomical telescopes of global significance.

The structure and function of this Special Standing Committee would closely track the proposal made in 2006 by former NSA [National Science Advisor] Dr Arthur Carty. We return to this topic in Chapter 6. For now, we observe that this approach would involve:

• a peer-reviewed decision on beginning an investment;

• a funded plan for the construction and operation of the facility, with continuing oversight by a peer specialist/agency review group for the specific facility;

• a plan for decommissioning; and

• a regular review scheduled to consider whether the facility still serves current needs.

We suggest that the committee have 10 members, with an eminent scientist as Chair. The members should include the CSA, two representatives from NACRI for liaison, and seven others. The other members should include Canadian and international scientists from a broad range of disciplines and experts on the construction, operation, and administration of MRFs. Consideration should be given to inviting the presidents of NRC [National Research Council of Canada] and CFI to serve as ex-officio members. The committee should be convened by the CSA, have access to the Secretariat associated with the CSA and NACRI, and report regularly to NACRI. (pp. 66-7 print; pp. 100-1 PDF)

I have the impression there’s been some ill feeling over the years regarding some of the major chunks of money given for ‘big science’. At a guess, direct appeals to a federal government that has no official mechanism for assessing the proposed ‘big science’ whether that means a major research facility (e.g., TRIUMF) or major science initiative (e.g., Pan Canadian Artificial Intelligence Strategy [keep reading to find out how I got the concept of a major science initiative wrong]) or 3rd party (MITACS) has seemed unfair to those who have to submit funding applications and go through vetting processes. This recommendation would seem to be an attempt to redress some of the issues.

Moving onto the third-party delivery and matching programs,

Three bodies in particular are the largest of these third-party organizations and illustrate the challenges of evaluating contribution agreements: Genome Canada, Mitacs, and Brain Canada. Genome Canada was created in 2000 at a time when many national genomics initiatives were being developed in the wake of the Human Genome Project. It emerged from a “bottom-up” design process driven by genomic scientists to complement existing programs by focusing on large-scale projects and technology platforms. Its funding model emphasized partnerships and matching funds to leverage federal commitments with the objective of rapidly ramping up genomics research in Canada.

This approach has been successful: Genome Canada has received $1.1 billion from the Government of Canada since its creation in 2000, and has raised over $1.6 billion through co-funding commitments, for a total investment in excess of $2.7 billion.34 The scale of Genome Canada’s funding programs allows it to support large-scale genomics research that the granting councils might otherwise not be able to fund. Genome Canada also supports a network of genomics technology and innovation centres with an emphasis on knowledge translation and has built domestic and international strategic partnerships. While its primary focus has been human health, it has also invested extensively in agriculture, forestry, fisheries, environment, and, more recently, oil and gas and mining— all with a view to the application and commercialization of genomic biotechnology.

Mitacs attracts, trains, and retains HQP [highly qualified personnel] in the Canadian research enterprise. Founded in 1999 as an NCE [Network Centre for Excellence], it was developed at a time when enrolments in graduate programs had flat-lined, and links between mathematics and industry were rare. Independent since 2011, Mitacs has focused on providing industrial research internships and postdoctoral fellowships, branching out beyond mathematics to all disciplines. It has leveraged funding effectively from the federal and provincial governments, industry, and not-for-profit organizations. It has also expanded internationally, providing two-way research mobility. Budget 2015 made Mitacs the single mechanism of federal support for postsecondary research internships with a total federal investment of $135.4 million over the next five years. This led to the wind-down of NSERC’s Industrial Postgraduate Scholarships Program. With matching from multiple other sources, Mitacs’ average annual budget is now $75 to $80 million. The organization aims to more than double the number of internships it funds to 10,000 per year by 2020.35

Finally, Brain Canada was created in 1998 (originally called NeuroScience Canada) to increase the scale of brain research funding in Canada and widen its scope with a view to encouraging interdisciplinary collaboration. In 2011 the federal government established the Canada Brain Research Fund to expand Brain Canada’s work, committing $100 million in new public investment for brain research to be matched 1:1 through contributions raised by Brain Canada. According to the STIC ‘State of the Nation’ 2014 report, Canada’s investment in neuroscience research is only about 40 per cent of that in the U.S. after adjusting for the size of the U.S. economy.36 Brain Canada may be filling a void left by declining success rates and flat funding at CIHR.

Recommendation and Elaboration

The Panel noted that, in general, third-party organizations for delivering research funding are particularly effective in leveraging funding from external partners. They fill important gaps in research funding and complement the work of the granting councils and CFI. At the same time, we questioned the overall efficiency of directing federal research funding through third-party organizations, noting that our consultations solicited mixed reactions. Some respondents favoured more overall funding concentrated in the agencies rather than diverting the funding to third-party entities. Others strongly supported the business models of these organizations.

We have indicated elsewhere that a system-wide review panel such as ours is not well-suited to examine these and other organizations subject to third-party agreements. We recommended instead in Chapter 4 that a new oversight body, NACRI, be created to provide expert advice and guidance on when a new entity might reasonably be supported by such an agreement. Here we make the case for enlisting NACRI in determining not just the desirability of initiating a new entity, but also whether contribution agreements should continue and, if so, on what terms.

The preceding sketches of three diverse organizations subject to contribution agreements help illustrate the rationale for this proposal. To underscore the challenges of adjudication, we elaborate briefly. Submissions highlighted that funding from Genome Canada has enabled fundamental discoveries to be made and important knowledge to be disseminated to the Canadian and international research communities. However, other experts suggested a bifurcation with CIHR or NSERC funding research-intensive development of novel technologies, while Genome Canada would focus on application (e.g., large-scale whole genome studies) and commercialization of existing technologies. From the Panel’s standpoint, these observations underscore the subtleties of determining where and how Genome Canada’s mandate overlaps and departs from that of CIHR and NSERC as well as CFI. Added to the complexity of any assessment is Genome Canada’s meaningful role in providing large-scale infrastructure grants and its commercialization program. Mitacs, even more than Genome Canada, bridges beyond academe to the private and non-profit sectors, again highlighting the advantage of having any review overseen by a body with representatives from both spheres. Finally, as did the other two entities, Brain Canada won plaudits, but some interchanges saw discussants ask when and whether it might be more efficient to flow this type of funding on a programmatic basis through CIHR.

We emphasize that the Panel’s intent here is neither to signal agreement nor disagreement with any of these submissions or discussions. We simply wish to highlight that decisions about ongoing funding will involve expert judgments informed by deep expertise in the relevant research areas and, in two of these examples, an ability to bridge from research to innovation and from extramural independent research to the private and non-profit sectors. Under current arrangements, management consulting firms and public servants drive the review and decision-making processes. Our position is that oversight by NACRI and stronger reliance on advice from content experts would be prudent given the sums involved and the nature of the issues. (pp. 102-4 print; pp. 136-8 PDF)

I wasn’t able to find anything other than this about major science initiatives (MSIs),

Big Science facilities, such as MSIs, have had particular challenges in securing ongoing stable operating support. Such facilities often have national or international missions. We termed them “major research facilities” (MRFs) xi in Chapter 4, and proposed an improved oversight mechanism that would provide lifecycle stewardship of these national science resources, starting with the decision to build them in the first instance. (p. 132 print; p. 166 PDF)

So, an MSI is an MRF? (head shaking) Why two terms for the same thing? And, how does the newly announced Pan Canadian Artificial Intelligence Strategy fit into the grand scheme of things?

The last ‘special case’ I’m featuring is the ‘Programme for Research Chairs for Excellent Scholars and Scientists’. Here’s what the report had to say about the state of affairs,

The major sources of federal funding for researcher salary support are the CRC [Canada Research Chair]and CERC [Canada Excellence Reseach Chair] programs. While some salary support is provided through council-specific programs, these investments have been declining over time. The Panel supports program simplification but, as noted in Chapter 5, we are concerned about the gaps created by the elimination of these personnel awards. While we focus here on the CRC and CERC programs because of their size, profile, and impact, our recommendations will reflect these concerns.

The CRC program was launched in 2000 and remains the Government of Canada’s flagship initiative to keep Canada among the world’s leading countries in higher education R&D. The program has created 2,000 research professorships across Canada with the stated aim “to attract and retain some of the world’s most accomplished and promising minds”5 as part of an effort to curtail the potential academic brain drain to the U.S. and elsewhere. The program is a tri-council initiative with most Chairs allocated to eligible institutions based on the national proportion of total research grant funding they receive from the three granting councils. The vast majority of Chairs are distributed based on area of research, of which 45 per cent align with NSERC, 35 per cent with CIHR, and 20 per cent with SSHRC; an additional special allocation of 120 Chairs can be used in the area of research chosen by the universities receiving the Chairs. There are two types of Chairs: Tier 1 Chairs are intended for outstanding researchers who are recognized as world leaders in their fields and are renewable; Tier 2 Chairs are targeted at exceptional emerging researchers with the potential to become leaders in their field and can be renewed once. Awards are paid directly to the universities and are valued at $200,000 annually for seven years (Tier 1) or $100,000 annually for five years (Tier 2). The program notes that Tier 2 Chairs are not meant to be a feeder group for Tier 1 Chairs; rather, universities are expected to develop a succession plan for their Tier 2 Chairs.

The CERC program was established in 2008 with the expressed aim of “support[ing] Canadian universities in their efforts to build on Canada’s growing reputation as a global leader in research and innovation.”6 The program aims to award world-renowned researchers and their teams with up to $10 million over seven years to establish ambitious research programs at Canadian universities, making these awards among the most prestigious and generous available internationally. There are currently 27 CERCs with funding available to support up to 30 Chairs, which are awarded in the priority areas established by the federal government. The awards, which are not renewable, require 1:1 matching funds from the host institution, and all degree-granting institutions that receive tri-council funding are eligible to compete. Both the CERC and CRC programs are open to Canadians and foreign citizens. However, until the most recent round, the CERCs have been constrained to the government’s STEM-related priorities; this has limited their availability to scholars and scientists from SSHRC-related disciplines. As well, even though Canadian-based researchers are eligible for CERC awards, the practice has clearly been to use them for international recruitment with every award to date going to researchers from abroad.

Similar to research training support, the funding for salary support to researchers and scholars is a significant proportion of total federal research investments, but relatively small with respect to the research ecosystem as a whole. There are more than 45,000 professors and teaching staff at Canada’s universities7 and a very small fraction hold these awards. Nevertheless, the programs can support research excellence by repatriating top Canadian talent from abroad and by recruiting and retaining top international talent in Canada.

The programs can also lead by example in promoting equity and diversity in the research enterprise. Unfortunately, both the CRC and CERC programs suffer from serious challenges regarding equity and diversity, as described in Chapter 5. Both programs have been criticized in particular for under-recruitment of women.

While the CERC program has recruited exclusively from outside Canada, the CRC program has shown declining performance in that regard. A 2016 evaluation of the CRC program8  observed that a rising number of chairholders were held by nominees who originated from within the host institution (57.5 per cent), and another 14.4 per cent had been recruited from other Canadian institutions. The Panel acknowledges that some of these awards may be important to retaining Canadian talent. However, we were also advised in our consultations that CRCs are being used with some frequency to offset salaries as part of regular faculty complement planning.

The evaluation further found that 28.1 per cent of current chairholders had been recruited from abroad, a decline from 32 per cent in the 2010 evaluation. That decline appears set to continue. The evaluation reported that “foreign nominees accounted, on average, for 13 per cent and 15 per cent respectively of new Tier 1 and Tier 2 nominees over the five-year period 2010 to 2014”, terming it a “large decrease” from 2005 to 2009 when the averages respectively were 32 per cent and 31 per cent. As well, between 2010-11 and 2014-15, the attrition rate for chairholders recruited from abroad was 75 per cent higher than for Canadian chairholders, indicating that the program is also falling short in its ability to retain international talent.9

One important factor here appears to be the value of the CRC awards. While they were generous in 2000, their value has remained unchanged for some 17 years, making it increasingly difficult to offer the level of support that world-leading research professors require. The diminishing real value of the awards also means that Chair positions are becoming less distinguishable from regular faculty positions, threatening the program’s relevance and effectiveness. To rejuvenate this program and make it relevant for recruitment and retention of top talent, it seems logical to take two steps:

• ask the granting councils and the Chairs Secretariat to work with universities in developing a plan to restore the effectiveness of these awards; and

• once that plan is approved, increase the award values by 35 per cent, thereby restoring the awards to their original value and making them internationally competitive once again.

In addition, the Panel observes that the original goal was for the program to fund 2,000 Chairs. Due to turnover and delays in filling Chair positions, approximately 10 to 15 per cent of them are unoccupied at any one time.i As a result, the program budget was reduced by $35 million in 2012. However, the occupancy rate has continued to decline since then, with an all-time low of only 1,612 Chair positions (80.6 per cent) filled as of December 2016. The Panel is dismayed by this inefficiency, especially at a time when Tier 2 Chairs remain one of the only external sources of salary support for ECRs [early career researchers]—a group that represents the future of Canadian research and scholarship. (pp. 142-4 print; pp. 176-8 PDF)

I think what you can see as a partial subtext in this report and which I’m attempting to highlight here in ‘special cases’ is a balancing act between supporting a broad range of research inquiries and focusing or pouring huge sums of money into ‘important’ research inquiries for high impact outcomes.

Final comments

There are many things to commend this report including the writing style. The notion that more coordination is needed amongst the various granting agencies, that greater recognition (i.e,, encouragement and funding opportunities) should be given to boundary-crossing research, and that we need to do more interprovincial collaboration is welcome. And yes, they want more money too. (That request is perfectly predictable. When was the last time a report suggested less funding?) Perhaps more tellingly, the request for money is buttressed with a plea to make it partisan-proof. In short, that funding doesn’t keep changing with the political tides.

One area that was not specifically mentioned, except when discussing prizes, was mathematics. I found that a bit surprising given how important the field of mathematics is to  to virtually all the ‘sciences’. A 2013 report, Spotlight on Science, suggests there’s a problem(as noted my Oct. 9, 2013 posting about that report,  (I also mention Canada’s PISA scores [Programme for International Student Assessment] by the OECD [Organization for Economic Cooperation and Development], which consistently show Canadian students at the age of 15 [grade 10] do well) ,

… it appears that we have high drop out rates in the sciences and maths, from an Oct. 8, 2013 news item on the CBC (Canadian Broadcasting Corporation) website,

… Canadians are paying a heavy price for the fact that less than 50 per cent of Canadian high school students graduate with senior courses in science, technology, engineering and math (STEM) at a time when 70 per cent of Canada’s top jobs require an education in those fields, said report released by the science education advocacy group Let’s Talk Science and the pharmaceutical company Amgen Canada.

Spotlight on Science Learning 2013 compiles publicly available information about individual and societal costs of students dropping out STEM courses early.

Even though most provinces only require math and science courses until Grade 10, the report [Spotlight on Science published by Let’s Talk Science and pharmaceutical company Amgen Canada) found students without Grade 12 math could expect to be excluded from 40 to 75 per cent of programs at Canadian universities, and students without Grade 11 could expect to be excluded from half of community college programs. [emphasis mine]

While I realize that education wasn’t the panel’s mandate they do reference the topic  elsewhere and while secondary education is a provincial responsibility there is a direct relationship between it and postsecondary education.

On the lack of imagination front, there was some mention of our aging population but not much planning or discussion about integrating older researchers into the grand scheme of things. It’s all very well to talk about the aging population but shouldn’t we start introducing these ideas into more of our discussions on such topics as research rather than only those discussions focused on aging?

Continuing on with the lack of  imagination and lack of forethought, I was not able to find any mention of independent scholars. The assumption, as always, is that one is affiliated with an institution. Given the ways in which our work world is changing with fewer jobs at the institutional level, it seems the panel was not focused on important and fra reaching trends. Also, there was no mention of technologies, such as artificial intelligence, that could affect basic research. One other thing from my wish list, which didn’t get mentioned, art/science or SciArt. Although that really would have been reaching.

Weirdly, one of the topics the panel did note, the pitiifull lack of interprovincial scientific collaboration, was completely ignored when it came time for recommendations.

Should you spot any errors in this commentary, please do drop me a comment.

Other responses to the report:

Nassif Ghoussoub (Piece of Mind blog; he’s a professor mathematics at the University of British Columbia; he attended one of the roundtable discussions held by the panel). As you might expect, he focuses on the money end of things in his May 1, 2017 posting.

You can find a series of essays about the report here under the title Response to Naylor Panel Report ** on the Canadian Science Policy Centre website.

There’s also this May 31, 2017 opinion piece by Jamie Cassels for The Vancouver Sun exhorting us to go forth collaborate internationally, presumably with added funding for the University of Victoria of which Cassels is the president and vice-chancellor. He seems not to have noticed that Canadian do much more poorly with interprovincial collaboration.

*ETA June 21, 2017: I’ve just stumbled across Ivan Semeniuk’s April 10, 2017 analysis (Globe and Mail newspaper) of the report. It’s substantive and well worth checking out.*

Again, here’s a link to the other parts:

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report) Commentaries

Part 1

Part 2

*’up’ added on June 8, 2017 at 15:10 hours PDT.

**’Science Funding Review Panel Repor’t was changed to ‘Responses to Naylor Panel Report’ on June 22, 2017.

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report): 2 of 3

This is the middle commentary on the report titled,(INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research). Part 1 of my commentary having provided some introductory material and first thoughts about the report, this part offers more detailed thoughts and Part 3 offers ‘special cases’ and sums up some of the ideas first introduced in part 1.

The report: the good, the informative, and the problematic

As Canadian government reports go, this is quite readable and I’m delighted to note some sections are downright engaging. (Thank you to the writer)

Happily, the report acknowledges the problems with the usual measures for research performance (p. xiv print; p. 18 PDF in the Executive Summary and, also, in Chapter 3). Also happily, the panel describes how the scope of the disciplines was decided,

Among the early challenges for the Panel were misinterpretation of its moniker and the related scope of its work. The term “fundamental science” originated with federal Budget 2016, which announced the Government of Canada’s intent to undertake a review.3 Alignment of terminology followed. Some members of the anglophone research community were understandably concerned that the Panel’s mandate excluded applied science in a range of fields, as well as the social sciences and humanities. Francophone researchers, accustomed to les sciences sociales et humaines, were more sanguine.

Minister Duncan [Kirsty Duncan], whose own scholarship cuts across the natural sciences, social sciences, and humanities, made it clear from the outset that the Panel was to examine the full range of scientific and scholarly disciplines. The Panel’s secretariat and members similarly emphasized the breadth of our review. We were accordingly delighted to receive submissions from many researchers and organizations representative of disciplines supported by the three granting councils, others doing transdisciplinary research who sometimes find themselves in limbo, and others again frustrated that the lack of collaboration across the councils has effectively shut out their disciplines altogether.

A residual source of some confusion was the term “fundamental”, which is used infrequently in the social sciences and humanities even though much scholarship in those fields is arguably basic or conceptual.

The Panel again took a pragmatic view. Our mandate was derived in meaningful measure from concerns that Canada’s capacity for generation of exciting new knowledge had been eroded. We therefore assumed our remit ranged from basic science focused on making major discoveries to applied science with important technological implications, and from deep philosophical inquiry to rigorous economic evaluations of policies and programs.

The Panel emphasizes in this latter regard that societies without great science and scholarship across a wide range of disciplines are impoverished in multiple dimensions. From the social sciences and humanities, contributions range from deeper understanding of the complexity of human nature and social structures to grace in self-expression and excellence and beauty in the creative and performing arts. From the natural and health sciences and engineering, while attention often focuses on practical applications, basic research provides the breakthrough insights that fundamentally change our understanding of the natural world and our cosmos. We return to this subject in Chapter 2.

The Panel also observes that these categorizations are all focused on research subject matter, when in fact the subject that really matters may be the person doing the research. Postsecondary education enriched by exposure to basic research provides citizens with an outlook and intellectual tools that are extraordinarily well-suited to technological and social innovation. Indeed, countless authors of abstract graduate theses have gone on to lives of deep and productive engagement with practical problems, bringing with them perspectives that reflect an inquiring and critical mind.

In brief, the Panel’s primary interest is in the extramural research realm, and particularly in supports for research into topics chosen by scholars and scientists from the full range of disciplines, using methods that they have developed or adapted, and subject to review by research colleagues. This research may be basic or applied. It may be project-based or programmatic. And it may have early application or no immediate relevance. However, a key criterion is that the work is sufficiently excellent to withstand critical scrutiny by peers, [emphasis mine] and produces knowledge that, after appropriate review, can be shared widely to advance the collective store of knowledge and ideas in the relevant field or fields. (p. 4-5 print; pp. 38-9 PDF)

Here’s a problem not mentioned in the report. Sometimes, the most exciting work is not appreciated or even approved by your peers. Daniel Schechtman’s work with quasicrystals  illustrates the issue (from the Dan Schechtman Wikipedia entry),

“I was a subject of ridicule and lectures about the basics of crystallography. The leader of the opposition to my findings was the two-time Nobel Laureate Linus Pauling, [emphasis mine] the idol of the American Chemical Society and one of the most famous scientists in the world. For years, ’til his last day, he fought against quasi-periodicity in crystals. He was wrong, and after a while, I enjoyed every moment of this scientific battle, knowing that he was wrong.”[citation needed]

Linus Pauling is noted saying “There is no such thing as quasicrystals, only quasi-scientists.”[15] Pauling was apparently unaware of a paper in 1981 by H. Kleinert and K. Maki which had pointed out the possibility of a non-periodic Icosahedral Phase in quasicrystals[16] (see the historical notes). The head of Shechtman’s research group told him to “go back and read the textbook” and a couple of days later “asked him to leave for ‘bringing disgrace’ on the team.”[17] [emphasis mine] Shechtman felt dejected.[15] On publication of his paper, other scientists began to confirm and accept empirical findings of the existence of quasicrystals.[18][19]

Schechtman does get back into the lab, finds support for his discovery from other scientists, and wins the Nobel Prize for Chemisty in 2011. But, that first few years was pretty rough sledding. As for the problem, how can you tell the difference between ground-breaking research and a ‘nutbar’ theory?

Getting back to the report, there’s a very nice listing of research milestones (the inception of various funding agencies, science ministries, important reports, and more) in the Canadian research landscape on pp. 8-9 print; pp. 42-3 PDF. The list stretches from 1916 to 2016. Oddly, the 2011 Jenkins report (also known as the Review of Federal Support to R&D report) is not on the list. Of course, it was a report commissioned by the then Conservative federal government.

Chapter 2 is the ‘Case for Science and Inquiry’ and it includes a bit of a history of the world, geologically speaking (p. 18 print; p. 52 PDF), and more. The scholars that are referenced tend to be from Europe and the US (sigh … isn’t there a way to broaden our perspectives?).

I was surprised that they didn’t include Wilder Penfield’s work in their partial listing of Canadian discoveries, and achievements in natural sciences, engineering, and health (p. 22 print; p. 56 PDF). From the Wilder Penfield Wikipedia entry*,

Wilder Graves Penfield OM CC CMG FRS[1] (January 26, 1891 – April 5, 1976) was an American-Canadian pioneering neurosurgeon once dubbed “the greatest living Canadian.”[2] He expanded brain surgery’s methods and techniques, including mapping the functions of various regions of the brain such as the cortical homunculus. His scientific contributions on neural stimulation expand across a variety of topics including hallucinations, illusions, and déjà vu. Penfield devoted a lot of his thinking to mental processes, including contemplation of whether there was any scientific basis for the existence of the human soul.[2]

Also mildly surprising was Ursula Franklin’s exclusion from their sampling of great Canadian thinkers in the social science and humanities (p. 23 print; p. 57 PDF) especially as there seems to be room for one more entry. From the Ursula Franklin Wikipedia entry,

Ursula Martius Franklin, CC OOnt FRSC (16 September 1921 – 22 July 2016), was a German-Canadian metallurgist, research physicist, author, and educator who taught at the University of Toronto for more than 40 years.[1] …

Franklin is best known for her writings on the political and social effects of technology. For her, technology was much more than machines, gadgets or electronic transmitters. It was a comprehensive system that includes methods, procedures, organization, “and most of all, a mindset”.[5] …

For some, Franklin belongs in the intellectual tradition of Harold Innis and Jacques Ellul who warn about technology’s tendency to suppress freedom and endanger civilization.[8] …

As noted earlier, Chapter 3 offers information about typical measures for scientific impact. There were two I didn’t mention. First, there are the scores for interprovincial collaboration. While we definitely could improve our international collaboration efforts, it’s the interprovincial efforts that tend to be pitiful (Note: I’ve had to create the table myself so it’s not identical to the report table’s format),

Province or Territory  Collaborative rates 2003-2014
Interprovincial International
Alberta 24.4 42.5
British Columbia 23.0 48.2
Manitoba 33.5 39.7
New Brunswick 35.7 38.0
Newfoundland and Labrador 33.6 38.7
Northwest Territories 86.9 32.5
Nova Scotia 34.7 40.9
Nunavut 85.7 34.5
Ontario 14.8 43.4
Prince Edward island 46.7 40.6
Québec 16.9 43.8
Saskatchewan 33.9 41.7
Yukon 79.4 39.0
Canada 9.8 43.7

* *The interprovincial collaboration rates (IPC) are computed on whole counts, not fractional counts. So, for example, a publication with authors from four provinces would count as one for Canada and one for each of the provinces. So the IPC for the whole of Canada would be 1 out of 874,475 (Canada’s whole publication count over 2003–2014) and the IPC for Ontario (for example) would be 1 out of 396,811 (the whole count for Ontario). Therefore the interprovincial collaboration rate would be lower for Canada than for Ontario. (p. 39 print; 73 PDF)

Second, there are the prizes,

Moving from highly-cited researchers and papers to the realm of major international research prizes takes us further into the realm of outlying talent. Major international prizes for research are relevant measures because they bring great prestige not just to individuals and teams, but also to institutions and nations. They are also the culmination of years of excellence in research and, particularly when prizes are won repeatedly across a range of disciplines, they send strong signals to the world about the health of a nation’s basic research ecosystem.

Unfortunately, Canada’s performance in winning international prizes is also lagging. In 2013 the Right Honourable David Johnston, Governor General of Canada, and Dr Howard Alper, then chair of the national Science, Technology and Innovation Council (STIC), observed that Canadians underperform “when it comes to the world’s most distinguished awards”, e.g., Nobel Prize, Wolf Prize, and Fields Medal. They added: “In the period from 1941 to 2008, Canadians received 19 of the top international awards in science—an impressive achievement, to be sure, but lacking when compared with the United States (with 1,403 winners), the United Kingdom (222), France (91), Germany (75) and Australia (42).”22 ix

There is an interesting wrinkle to the dominance of the U.S. in Nobel prizes.23 Over 30 per cent of all U.S. Nobel laureates since 1950 were foreign-born, with that proportion rising over time. From 2007 to 2016, the 54 Nobel prizes awarded to U.S.-based researchers included 20 immigrants. Sources differ as to whether more of the U.S. Nobel laureates originated from Canada or Germany, but the best estimate is that, since 1901, there have been 15 Canadian-born, and in many cases Canadian-educated, Nobel laureates based in the U.S.—double the total number of Nobel prizes awarded to Canadian-based researchers in the same period.

From the standpoint of international recognition, 2015 was an exceptional year. Canadians won two of the pinnacle awards: a Nobel prize (Arthur McDonald for Physics) and a Wolf prize (James Arthur for Mathematics). Those prizes celebrate work that exemplifies two very different models of discovery. As a theoretical mathematician, Dr Arthur’s pioneering papers in automorphic forms have been overwhelmingly sole-authored; his long-term support has come from modest NSERC Discovery Grants. As a particle physicist, Dr McDonald has led a large team in developing and operating the renowned Sudbury Neutrino Laboratory, a major science facility purpose-built deep in an active nickel mine, where startling observations have been made that are forcing a reconsideration of The Standard Model for Elementary Particles. In both cases, however, what matters is that the work began decades ago, and Canada provided long-term support at the levels and in forms required to enable path-breaking discoveries to be made.

Canada cannot assume that there will be a series of other pinnacle prizes awarded based on discoveries that tap into work initiated in the 1970s and 1980s. To ensure a continuous pipeline of successful nominations for international awards, research institutions must be supported consistently to recruit and retain outstanding scholars and scientists. They in turn must be supported to create world-class research environments through meritocratic adjudication processes that offer fair access to appropriate levels of consistent funding for scientific inquiry. Our assessment thus far has not given us great confidence that these winning conditions are being created, let alone enhanced. (pp. 46-7 print; pp. 80-1 PDF)

I found one more interesting bit in the report, a dated list of Canadian science advice vehicles. Somewhat optimistically given the speed with which the initiative has moved forward, they’ve listed a Canadian chief science advisor for 2017 (p. 54 print; p. 88 PDF). Understandably, since it is a recommendation, they left out the NACRI, .

Again, here’s a link to the other parts:

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report) Commentaries

Part 1

Part 3

*’enty’ corrected to ‘entry’ and a link to Wilder Penfield’s Wikipedia entry was added on June 15, 2017.

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report): 1 of 3

This sucker (INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research, also known as, Canada’s Fundamental Science Review 2017 or the Naylor report) is a 280 pp. (PDF) and was released on Monday, April 10, 2017. I didn’t intend that this commentary should stretch out into three parts (sigh). Them’s the breaks. This first part provides an introduction to the panel and the report as well as some ‘first thoughts’. Part 2 offers more detailed thoughts and Part 3 offers ‘special cases’ and sums up some of the ideas first introduced in part 1.

I first wrote about this review in a June 15, 2017 posting where amongst other comments I made this one,

Getting back to the review and more specifically, the panel, it’s good to see that four of the nine participants are women but other than that there doesn’t seem to be much diversity, i.e.,the majority (five) spring from the Ontario/Québec nexus of power and all the Canadians are from the southern part of country. Back to diversity, there is one business man, Mike Laziridis known primarily as the founder of Research in Motion (RIM or more popularly as the Blackberry company) making the panel not a wholly ivory tower affair. Still, I hope one day these panels will have members from the Canadian North and international members who come from somewhere other than the US, Great Britain, and/or if they’re having a particularly wild day, Germany. Here are some candidate countries for other places to look for panel members: Japan, Israel, China, South Korea, and India. Other possibilities include one of the South American countries, African countries, and/or the Middle Eastern countries.

Take the continent of Africa for example, where many countries seem to have successfully tackled one of the issues as we face. Specifically, the problem of encouraging young researchers. …

Here’s a quick summary about the newly released report from the April 10, 2017 federal government news release on Canada’s Public Policy Forum,

Today [April 10, 2017], the Government of Canada published the final report of the expert panel on Canada’s Fundamental Science Review. Commissioned by the Honourable Kirsty Duncan, Minister of Science, the report by the blue-ribbon panel offers a comprehensive review of the mechanisms for federal funding that supports research undertaken at academic institutions and research institutes across Canada, as well as the levels of that funding. It provides a multi-year blueprint for improving the oversight and governance of what the panelists call the “research ecosystem.” The report also recommends making major new investments to restore support for front-line research and strengthen the foundations of Canadian science and research at this pivotal point in global history.

The review is the first of its type in more than 40 years. While it focused most closely on the four major federal agencies that support science and scholarly inquiry across all disciplines, the report also takes a wide-angle view of governance mechanisms ranging from smaller agencies to big science facilities. Another issue closely examined by the panel was the effect of the current configuration of funding on the prospects of early career researchers—a group that includes a higher proportion of women and is more diverse than previous generations of scientists and scholars.

The panel’s deliberations were informed by a broad consultative process. The panel received 1,275 written submissions [emphasis mine] from individuals, associations and organizations. It also held a dozen round tables in five cities, engaging some 230 researchers [emphasis mine] at different career stages.

Among the findings:

  • Basic research worldwide has led to most of the technological, medical and social advances that make our quality of life today so much better than a century ago. Canadian scientists and scholars have contributed meaningfully to these advances through the decades; however, by various measures, Canada’s research competitiveness has eroded in recent years.
  • This trend emerged during a period when there was a drop of more than 30 percent in real per capita funding for independent or investigator-led research by front-line scientists and scholars in universities, colleges, institutes and research hospitals. This drop occurred as a result of caps on federal funding to the granting councils and a dramatic change in the balance of funding toward priority-driven and partnership-oriented research.
  • Canada is an international outlier in that funding from federal government sources accounts for less than 25 percent of total spending on research and development in the higher education sector. While governments sometimes highlight that, relative to GDP, Canada leads the G7 in total spending by this sector, institutions themselves now underwrite 50 percent of these costs—with adverse effects on both research and education.
  • Coordination and collaboration among the four key federal research agencies [Canada Foundation for Innovation {CFI}; Social Sciences and Humanities Research Council {SSHRC}; Natural Sciences and Engineering Research Council {NSERC}; Canadian Institutes of Health Research {CIHR}] is suboptimal, with poor alignment of supports for different aspects of research such as infrastructure, operating costs and personnel awards. Governance and administrative practices vary inexplicably, and support for areas such as international partnerships or multidisciplinary research is uneven.
  • Early career researchers are struggling in some disciplines, and Canada lacks a career-spanning strategy for supporting both research operations and staff.
  • Flagship personnel programs such as the Canada Research Chairs have had the same value since 2000. Levels of funding and numbers of awards for students and post-doctoral fellows have not kept pace with inflation, peer nations or the size of applicant pools.

The report also outlines a comprehensive agenda to strengthen the foundations of Canadian extramural research. Recommended improvements in oversight include:

  • legislation to create an independent National Advisory Council on Research and Innovation (NACRI) that would work closely with Canada’s new Chief Science Advisor (CSA) to raise the bar in terms of ongoing evaluations of all research programming;
  • wide-ranging improvements to oversight and governance of the four agencies, including the appointment of a coordinating board chaired by the CSA; and
  • lifecycle governance of national-scale research facilities as well as improved methods for overseeing and containing the growth in ad-hoc funding of smaller non-profit research entities.

With regard to funding, the panel recommends a major multi-year reinvestment in front-line research, targeting several areas of identified need. Each recommendation is benchmarked and is focused on making long-term improvements in Canada’s research capacity. The panel’s recommendations, to be phased in over four years, would raise annual spending across the four major federal agencies and other key entities from approximately $3.5 billion today to $4.8 billion in 2022. The goal is to ensure that Canada benefits from an outsized concentration of world-leading scientists and scholars who can make exciting discoveries and generate novel insights while educating and inspiring the next generation of researchers, innovators and leaders.

Given global competition, the current conditions in the ecosystem, the role of research in underpinning innovation and educating innovators, and the need for research to inform evidence-based policy-making, the panel concludes that this is among the highest-yield investments in Canada’s future that any government could make.

The full report is posted on www.sciencereview.ca.

Quotes

“In response to the request from Prime Minister Trudeau and Minister Duncan, the Science Review panel has put together a comprehensive roadmap for Canadian pre-eminence in science and innovation far into the future. The report provides creative pathways for optimizing Canada’s investments in fundamental research in the physical, life and social sciences as well as the humanities in a cost effective way. Implementation of the panel’s recommendations will make Canada the destination of choice for the world’s best talent. It will also guarantee that young Canadian researchers can fulfill their dreams in their own country, bringing both Nobel Prizes and a thriving economy to Canada. American scientists will look north with envy.”

– Robert J. Birgeneau, Silverman Professor of Physics and Public Policy, University of California, Berkeley

“We have paid close attention not only to hard data on performance and funding but also to the many issues raised by the science community in our consultations. I sincerely hope the report will serve as a useful guide to policy-makers for years to come.”

– Martha Crago, Vice-President, Research and Professor of Human Communication Disorders, Dalhousie University

“Science is the bedrock of modern civilization. Our report’s recommendations to increase and optimize government investments in fundamental scientific research will help ensure that Canada’s world-class researchers can continue to make their critically important contributions to science, industry and society in Canada while educating and inspiring future generations. At the same time, such investments will enable Canada to attract top researchers from around the world. Canada must strategically build critical density in our researcher communities to elevate its global competitiveness. This is the path to new technologies, new businesses, new jobs and new value creation for Canada.”

– Mike Lazaridis, Founder and Managing Partner, Quantum Valley Investments

“This was a very comprehensive review. We heard from a wide range of researchers—from the newest to those with ambitious, established and far-reaching research careers. At all these levels, researchers spoke of their gratitude for federal funding, but they also described enormous barriers to their success. These ranged from personal career issues like gaps in parental leave to a failure to take gender, age, geographic location and ethnicity into account. They also included mechanical and economic issues like gaps between provincial and federal granting timelines and priorities, as well as a lack of money for operating and maintaining critical equipment.”

– Claudia Malacrida, Associate Vice-President, Research and Professor of Sociology, University of Lethbridge

“We would like to thank the community for its extensive participation in this review. We reflect that community perspective in recommending improvements to funding and governance for fundamental science programs to restore the balance with recent industry-oriented programs and improve both science and innovation in Canada.”

– Arthur B. McDonald, Professor Emeritus, Queen’s University

“This report sets out a multi-year agenda that, if implemented, could transform Canadian research capacity and have enormous long-term impacts across the nation. It proffers a legacy-building opportunity for a new government that has boldly nailed its colours to the mast of science and evidence-informed policy-making. I urge the Prime Minister to act decisively on our recommendations.”

– C. David Naylor, Professor of Medicine, University of Toronto (Chair)

“This report outlines all the necessary ingredients to advance basic research, thereby positioning Canada as a leading ‘knowledge’ nation. Rarely does a country have such a unique opportunity to transform the research landscape and lay the foundation for a future of innovation, prosperity and well-being.”

– Martha C. Piper, President Emeritus, University of British Columbia

“Our report shows a clear path forward. Now it is up to the government to make sure that Canada truly becomes a world leader in how it both organizes and financially supports fundamental research.”

– Rémi Quirion, Le scientifique en chef du Québec

“The government’s decision to initiate this review reflected a welcome commitment to fundamental research. I am hopeful that the release of our report will energize the government and research community to take the next steps needed to strengthen Canada’s capacity for discovery and research excellence. A research ecosystem that supports a diversity of scholars at every career stage conducting research in every discipline will best serve Canada and the next generation of students and citizens as we move forward to meet social, technological, economic and ecological challenges.”

– Anne Wilson, Professor of Psychology, Wilfrid Laurier University

Quick facts

  • The Fundamental Science Review Advisory Panel is an independent and non-partisan body whose mandate was to provide advice and recommendations to the Minister of Science on how to improve federal science programs and initiatives.
  • The panel was asked to consider whether there are gaps in the federal system of support for fundamental research and recommend how to address them.
  • The scope of the review included the federal granting councils along with some federally funded organizations such as the Canada Foundation for Innovation.

First thoughts

Getting to the report itself, I have quickly skimmed through it  but before getting to that and for full disclosure purposes, please note, I made a submission to the panel. That said, I’m a little disappointed. I would have liked to have seen a little more imagination in the recommendations which set forth future directions. Albeit the questions themselves would not seem to encourage any creativity,

Our mandate was summarized in two broad questions:

1. Are there any overall program gaps in Canada’s fundamental research funding ecosystem that need to be addressed?

2. Are there elements or programming features in other countries that could provide a useful example for the Government of Canada in addressing these gaps? (p. 1 print; p. 35 PDF)

A new agency to replace the STIC (Science, Technology and Innovation Council)

There are no big surprises. Of course they’ve recommended another organization, NACRI [National Advisory Council on Research and Innovation], most likely to replace the Conservative government’s advisory group, the Science, Technology and Innovation Council (STIC) which seems to have died as of Nov. 2015, one month after the Liberals won. There was no Chief Science Advisor under the Conservatives. As I recall, the STIC replaced a previous Liberal government’s advisory group and Chief Science Advisor (Arthur Carty, now the executive director of the Waterloo [as in University of Waterloo] Institute of Nanotechnology).

Describing the NACRI as peopled by volunteers doesn’t exactly describe the situation. This is the sort of ‘volunteer opportunity’ a dedicated careerist salivates over because it’s a career builder where you rub shoulders with movers and shakers in other academic institutions, in government, and in business. BTW, flights to meetings will be paid for along with per diems (accommodations and meals). These volunteers will also have a staff. Admittedly, it will be unpaid extra time for the ‘volunteer’ but the payoff promises to be considerable.

Canada’s eroding science position

There is considerable concern evinced over Canada’s eroding position although we still have bragging rights in some areas (regenerative medicine, artificial intelligence for two areas). As for erosion, the OECD (Organization for Economic Cooperation and Development) dates the erosion back to 2001 (from my June 2, 2014 posting),

Interestingly, the OECD (Organization for Economic Cooperation and Development) Science, Technology and Industry Scoreboard 2013 dates the decline to 2001. From my Oct. 30, 2013 posting (excerpted from the scorecard),

Canada is among the few OECD countries where R&D expenditure declined between 2000 and 2011 (Figure 1). This decline was mainly due to reduced business spending on R&D. It occurred despite relatively generous public support for business R&D, primarily through tax incentives. In 2011, Canada was amongst the OECD countries with the most generous tax support for R&D and the country with the largest share of government funding for business R&D being accounted for by tax credits (Figure 2). …

It should be noted, the Liberals have introduced another budget with flat funding for science (if you want to see a scathing review see Nassif Ghoussoub’s (professor of mathematics at the University of British Columbia April 10, 2017 posting) on his Piece of Mind blog). Although the funding isn’t quite so flat as it might seem at first glance (see my March 24, 2017 posting about the 2017 budget). The government explained that the science funding agencies didn’t receive increased funding as the government was waiting on this report which was released only weeks later (couldn’t they have a sneak preview?). In any event, it seems it will be at least a year before the funding issues described in the report can be addressed through another budget unless there’s some ‘surprise’ funding ahead.

Again, here’s a link to the other parts:

INVESTING IN CANADA’S FUTURE; Strengthening the Foundations of Canadian Research (Review of fundamental research final report) Commentaries

Part 2

Part 3

Sustainable water desalination with self-cleaning membranes

This desalination technology comes from the United Arab Emirates (UAE). from an April 13, 2017 news item on Nanowerk,

An advanced water treatment membrane made of electrically conductive nanofibers developed at Masdar Institute was highlighted by Dr. Raed Hashaikeh, Professor of Mechanical and Materials Engineering at Masdar Institute, in his keynote speech during the 3rd International Conference on Desalination using Membrane Technology held last week in Spain.

An April 13, 2017 Masdar Institute press release by Erica Solomon, which originated the news item, expands on the theme,

Self-cleaning membranes offer a critically needed solution to the problem of fouling, which is the unwanted build-up of organic and inorganic deposits on a membrane’s surface that reduces the membrane’s ability to filter impurities. Water treatment and purification membranes that can easily clean themselves when fouled could make pressure-driven membrane filtration systems used to treat and desalinate water more energy-efficient.

“Keeping membranes clean, permeable and functional is a great challenge to membrane desalination technologies. When a membrane becomes fouled, its pores get blocked and its flux is severely reduced, which means that much less water can pass through the membrane at a constant pressure,” Dr. Hashaikeh explained.

Conventional methods for cleaning fouled membranes involve expensive and harsh chemical treatments, and often lead to water treatment plant shut-downs, which can cost millions of dollars in lost operational hours. In the UAE, annual spending on desalination is already estimated to cost AED12 billion, indicating a pressing need for solutions that avoid costly shut-downs and treatments.

In addition to posing a heavy financial burden, fouled membranes are also a sustainability issue, as once a membrane becomes fouled, the higher pressure needed to push water through clogged pores significantly increases the plant’s energy consumption. The harsh chemicals used to clean a fouled membrane are also bad for the environment and require neutralizing. Thus, finding a way to easily and quickly clean fouled membranes not only makes financial sense, but environmental sense.

In a country like the UAE, where natural gas-powered thermal desalination produces over 80% of the country’s domestic water, innovative technologies like self-cleaning membranes to support a shift toward lower-energy and lower-cost membrane-based desalination are essential for achieving economic and environmental balance while meeting the UAE’s water demands.

And now, Dr. Hashaikeh’s research group may have brought the UAE closer towards realizing a more sustainable and economic approach to membrane desalination through their research on the application of advanced nanofibers for enhanced, self-cleaning membranes.

The group has leveraged the electrically conductive nature of a special kind of nanofiber, called carbon nanotubes (CNT). CNTs are tiny cylindrical tubes made of tightly bonded carbon atoms, measuring just one atom thick. But the CNTs Dr. Hashaikeh’s team used, which were provided by global security, aerospace, and information technology company Lockheed Martin, are not ordinary CNTs.

“The carbon nanostructures supplied by Lockheed Martin are special; they are networked. This means that they are composed of many interconnecting channels that branch off in all directions. This interconnectivity is what enables the entire membrane to become completely cleaned when electricity is applied to it,” Dr. Hashaikeh said.

The networked CNTs, also known as carbon nanostructures (CNS), coupled with the team’s expert membrane fabrication know-how, resulted in the development of two different types of membranes that can clean themselves when a low-voltage electric current is run through them.

The first type is a microfiltration membrane, which has pores sizes ranging from 100 nanometers to 10 micrometers, where a nanometer is approximately one hundred thousand times smaller than the width of a human hair and a micrometer one thousand times larger than a nanometer. The second is a nanofiltration membrane with pore sizes ranging from one to ten nanometers. Both membranes demonstrated the ability to clean themselves in response to an electric shock, which resulted in the immediate restoration of the membranes’ flux.

Dr. Hashaikeh’s investigation of a self-cleaning membrane began four years ago, when he realized that electrolytic cleaning – which is the process of removing soil, scale or corrosion from a metal’s surface by subjecting it to an electric current – could also be used to clean membranes. To prove his theory, he coated a membrane with ordinary CNTs. When a voltage was applied to the membrane, the parts of the membranes that were coated with CNTs were successfully cleaned. Dr. Hashaikeh filed a patent for this in-situ electrolytic cleaning process with the United States Patent and Trademark Office (USPTO) in 2014.

However, there were limitations to this discovery, namely that only specific areas in the coated CNTs were cleaned, not the entire membrane. Thus, to develop an efficient, self-cleaning membrane with commercial potential, Dr. Hashaikeh required a material that would easily allow electric shockwaves to penetrate through the entire membrane’s surface area.

The unique, interconnected structure of Lockheed Martin’s carbon nanostructures proved to be just the right type of electrically conductive, nano-fibrous material required.

“We immediately recognized that Lockheed Martin’s CNTs might enable electricity to pass through the entire surface, but we had to modify the nanostructures to transform the material into a membrane. To do this, we controlled certain properties, such as wettability and pore size, and improved its mechanical strength by incorporating polymer materials,” he explained.

Dr. Haishaikeh’s team successfully developed a self-cleaning microfiltration membrane in 2014 and a paper describing the research was published in the Journal of Membrane Science. But they did not stop there; they wanted to take their research a step further and find a way to develop a self-cleaning nanofiltration membrane. While microfiltration membranes are useful for removing larger particles, including sand, silt, clays, algae and some forms of bacteria, nanofiltration membranes can go a step further, removing most organic molecules, nearly all viruses, most of the natural organic matter and a range of salts. Nanofiltration membranes also remove divalent ions, which make water hard, making nanofiltration a popular and eco-friendly option to soften hard water.

To create self-cleaning nanofiltration membranes out of Lockheed Martin’s networked CNTs, the team needed to overcome the problem of the CNTs’ large pore sizes, which prevented the material from functioning as a nanofiltration membrane.

To achieve this they looked to a second advanced nanofiber material previously developed by Dr. Hashaikeh’s research group, known as networked cellulose. Networked cellulose is a modified type of cellulose made from wood pulp. When dried, the networked cellulose gel shrinks in volume, but maintains its integrity and shape, becoming harder as it shrinks. The research team asserted that the networked cellulose gel could reduce the membrane’s pore sizes while maintaining its structural integrity.

The researchers then mixed the carbon nanostructures with the networked cellulose gel and as the mixture dried, the networked cellulose shrank. The shrinking of the network cellulose in turn pressurized the nanostructures in the membrane. The resulting membrane is strong with much smaller pore sizes. Dr. Hashaikeh reports that the pore size dropped from 60 nanometers to just three nanometers with the addition of the networked cellulose in a paper describing the study, which was published in the journal Desalination last month. Co-authors from Masdar Institute include PhD student Farah Ahmad and postdoctoral researcher Boor Lalia, along with Dr. Nidal Hilal of Swansea University.

Dr. Hashaikeh’s prolific scientific contribution to the field of membrane desalination has led to his recent appointment as an associate editor for the journal Desalination; a position that is essential to the quality of the international journal and its peer review process.

The innovative research conducted by Dr. Hashaikeh and the team will help position Abu Dhabi as a leader in membrane desalination research and technology development. This project has already yielded a patent filing, and is hoped to provide the emirate with novel intellectual property in the critical industry of desalination.

Here are the links and citations for the 2014 and 2017 papers,

A novel in situ membrane cleaning method using periodic electrolysis by Raed Hashaikeh, Boor Singh Lalia, Victor Kochkodan, Nidal Hilal. Journal of Membrane Science Volume 471, 1 December 2014, Pages 149–154 https://doi.org/10.1016/j.memsci.2014.08.017

Electrically conducting nanofiltration membranes based on networked cellulose and carbon nanostructures by Farah Ejaz Ahmed, Boor Singh Lalia, Nidal Hilal, Raed Hashaikeh. Desalination Volume 406, 16 March 2017, Pages 60–66 https://doi.org/10.1016/j.desal.2016.09.005

Both papers a behind a paywall.

Job posting: G20 Water Technologies is looking for a PhD level scientist to join a fast-growing and well-funded start-up company developing graphene based water treatment.

This is the June 6, 2017 G20 Water Technologies notice I received via email,

Senior Application Scientist Vacancy

This is an opportunity for a PhD level scientist to join a fast growing
and well funded start up developing graphene based water treatment.

The company has developed coatings for existing filter materials with
applications in oil/water separation, waste water treatment, dehydration
of organic liquids and desalination, with addressable markets in excess
of £2.8Bn.

We have a vacancy for an exceptional individual with an in depth
understanding of membranes and 2D materials to join our team as a Senior
Application Scientist. This post carries a high degree of responsibility
to deliver results, a salary to match, will report directly to the
company’s CEO and will be based with the Water@Leeds interdisciplinary
group in the University of Leeds.

Key responsibilities include:

* Managing the company’s internal and external research and
development activities with both academic and commercial partners;
* To further develop graphene oxide (GO)-based coatings/membranes for
highly efficient water purification. This will involve working closely
with materials suppliers and end users to understand and deliver the
required performance;
* Developing test methodologies to quantify membrane performance
* Supporting current and future government funded grant work;
* Further developing and strengthening G2O’s IP portfolio.

The successful candidate will be expected to have:

* The ability to design, manage and deliver technology R&D projects;
* Experience in working with academic institutions in an industrial
environment;
* An in depth knowledge of formulation of 2D material dispersions;
* A PhD or other suitable academic qualifications to be accepted as a
Visiting Fellow by the company’s academic partners.

Before getting to the contact information, a few words about one of the company’s principles, Tim Harper, G20 Chief Executive Officer. I’ve never met him in person but have known him online for many years (we’ve exchanged emails and tweets). He has been an active member of the ‘nano’ blogosphere and social media environment for many years. He has run his own consultation company (on emerging technologies), Cientifica (About Us) since 1997, and other companies. He’s been involved with the World Economic Forum and has consulted internationally for governments and other entities. That said, there are no guarantees with start-up companies and you do need to perform your own due diligence as I’m sure Tim Harper would counsel you. One other piece of information before you dash off, the company’s headquarters are in Manchester where its university boasts it’s the ‘home of graphene’ and houses the National Graphene Institute.

Here are a few places you might want to check:

G20 website

About G20 webpage

Contact us (for more details about the position)

Good Luck!

Locusts inspire new aerosol-based nanoparticle drug delivery system

Getting medication directly to the brain is a worldwide medical research goal and it seems that a team of scientists at the Washington University at St. Louis (WUSTL) has taken a step forward to accomplishing the goal. From an April 12, 2017 news item on ScienceDaily,

Delivering life-saving drugs directly to the brain in a safe and effective way is a challenge for medical providers. One key reason: the blood-brain barrier, which protects the brain from tissue-specific drug delivery. Methods such as an injection or a pill aren’t as precise or immediate as doctors might prefer, and ensuring delivery right to the brain often requires invasive, risky techniques.

A team of engineers from Washington University in St. Louis has developed a new nanoparticle generation-delivery method that could someday vastly improve drug delivery to the brain, making it as simple as a sniff.

“This would be a nanoparticle nasal spray, and the delivery system could allow a therapeutic dose of medicine to reach the brain within 30 minutes to one hour,” said Ramesh Raliya, research scientist at the School of Engineering & Applied Science.

Caption: Engineers at Washington University have discovered a new technique that could change drug delivery to the brain. They were able to apply a nanoparticle aerosol spray to the antenna of locusts, then track the nanoparticles as they traveled through the olfactory nerves, crossed the blood-brain barrier and accumulated in the brain. This new, non-invasive approach could someday make drug delivery as simple as a sniff for patients with brain injuries or tumors.

Credit: Washington University in St. Louis

An April 12, 2017 WUSTL news release by Erika Ebsworth-Goold (also on EurekAlert), which originated the news item, describes the work in more detail,

“The blood-brain barrier protects the brain from foreign substances in the blood that may injure the brain,” Raliya said. “But when we need to deliver something there, getting through that barrier is difficult and invasive. Our non-invasive technique can deliver drugs via nanoparticles, so there’s less risk and better response times.”

The novel approach is based on aerosol science and engineering principles that allow the generation of monodisperse nanoparticles, which can deposit on upper regions of the nasal cavity via diffusion. Working with Assistant Vice Chancellor Pratim Biswas, chair of the Department of Energy, Environmental & Chemical Engineering and the Lucy & Stanley Lopata Professor, Raliya developed an aerosol consisting of gold nanoparticles of controlled size, shape and surface charge. The nanoparticles were tagged with fluorescent markers, allowing the researchers to track their movement.

Next, Raliya and biomedical engineering postdoctoral fellow Debajit Saha exposed locusts’ antennae to the aerosol, and observed the nanoparticles travel from the antennas up through the olfactory nerves. Due to their tiny size, the nanoparticles passed through the brain-blood barrier, reaching the brain and suffusing it in a matter of minutes.

The team tested the concept in locusts because the blood-brain barriers in the insects and humans have anatomical similarities, and the researchers consider going through the nasal regions to neural pathways as the optimal way to access the brain.

“The shortest and possibly the easiest path to the brain is through your nose,” said Barani Raman, associate professor of biomedical engineering. “Your nose, the olfactory bulb and then olfactory cortex: two relays and you’ve reached the cortex. The same is true for invertebrate olfactory circuitry, although the latter is a relatively simpler system, with supraesophageal ganglion instead of an olfactory bulb and cortex.”

To determine whether or not the foreign nanoparticles disrupted normal brain function, Saha examined the physiological response of olfactory neurons in the locusts before and after the nanoparticle delivery. Several hours after the nanoparticle uptake, no noticeable change in the electrophysiological responses was detected.

“This is only a beginning of a cool set of studies that can be performed to make nanoparticle-based drug delivery approaches more principled,” Raman said.

The next phase of research involves fusing the gold nanoparticles with various medicines, and using ultrasound to target a more precise dose to specific areas of the brain, which would be especially beneficial in brain-tumor cases.

“We want to drug target delivery within the brain using this non-invasive approach,” Raliya said.  “In the case of a brain tumor, we hope to use focused ultrasound so we can guide the particles to collect at that particular point.”

Here’s a link to and a citation for the paper,

Non-invasive aerosol delivery and transport of gold nanoparticles to the brain by Ramesh Raliya, Debajit Saha, Tandeep S. Chadha, Baranidharan Raman, & Pratim Biswas. Scientific Reports 7, Article number: 44718 (2017) doi:10.1038/srep44718 Published online: 16 March 2017

This paper is open access.

I featured another team working on delivering drugs directly to the brain via the olfactory system, except their nanoparticles were gelatin and they were testing stroke medication on rats, in my Sept. 24, 2014 posting.

‘Hunting’ pharmaceuticals and removing them from water

Pharmaceuticals are not the first pollutants people think of when discussing water pollution but, for those who don’t know, it’s a big issue and scientists at the University of Surrey (UK) have developed a technology they believe will help to relieve the contamination. From an April 10, 2017 University of Surrey press release (also on EurekAlert),

The research involves the detection and removal of pharmaceuticals in or from water, as contamination from pharmaceuticals can enter the aquatic environment as a result of their use for the treatment of humans and animals. This contamination can be excreted unchanged, as metabolites, as unused discharge or by drug manufacturers.

The research has found that a new type of ‘supermolecule’, calix[4], actively seeks certain pharmaceuticals and removes them from water.

Contamination of water is a serious concern for environmental scientists around the world, as substances include hormones from the contraceptive pill, and pesticides and herbicides from allotments. Contamination can also include toxic metals such as mercury, arsenic, or cadmium, which was previously used in paint, or substances that endanger vital species such as bees.

Professor Danil de Namor, University of Surrey Emeritus Professor and leader of the research, said: “Preliminary extraction data are encouraging as far as the use of this receptor for the selective removal of these drugs from water and the possibility of constructing a calix[4]-based sensing devices.

“From here, we can design receptors so that they can bind selectively with pollutants in the water so the pollutants can be effectively removed. This research will allow us to know exactly what is in the water, and from here it will be tested in industrial water supplies, so there will be cleaner water for everyone.

“The research also creates the possibility of using these materials for on-site monitoring of water, without having to transport samples to the laboratory.”

Dr Brendan Howlin, University of Surrey co-investigator, said: “This study allows us to visualise the specific receptor-drug interactions leading to the selective behaviour of the receptor. As well as the health benefits of this research, molecular simulation is a powerful technique that is applicable to a wide range of materials.

“We were very proud that the work was carried out with PhD students and a final year project student, and research activities are already taking place with the Department of Chemical and Processing Engineering (CPI) and the Advanced Technology Institute (ATI).

“We are also very pleased to see that as soon as the paper was published online by the European Journal of Pharmaceutical Sciences, we received invitations to give keynote lectures at two international conferences on pharmaceuticals in Europe later this year.”

That last paragraph is intriguing and it marks the first time I’ve seen that claim in a press release announcing the publication of a piece of research.

Here’s a link to and a citation for the paper,

A calix[4]arene derivative and its selective interaction with drugs (clofibric acid, diclofenac and aspirin) by Angela F Danil de Namor, Maan Al Nuaim, Jose A Villanueva Salas, Sophie Bryant, Brendan Howlin. European Journal of Pharmaceutical Sciences Volume 100, 30 March 2017, Pages 1–8 https://doi.org/10.1016/j.ejps.2016.12.027

This paper is behind a paywall.

Nanoparticles and strange forces

An April 10, 2017 news item on Nanowerk announces work from the University of New Mexico (UNM), Note: A link has been removed,

A new scientific paper published, in part, by a University of New Mexico physicist is shedding light on a strange force impacting particles at the smallest level of the material world.

The discovery, published in Physical Review Letters (“Lateral Casimir Force on a Rotating Particle near a Planar Surface”), was made by an international team of researchers lead by UNM Assistant Professor Alejandro Manjavacas in the Department of Physics & Astronomy. Collaborators on the project include Francisco Rodríguez-Fortuño (King’s College London, U.K.), F. Javier García de Abajo (The Institute of Photonic Sciences, Spain) and Anatoly Zayats (King’s College London, U.K.).

An April 7,2017 UNM news release by Aaron Hill, which originated the news item, expands on the theme,

The findings relate to an area of theoretical nanophotonics and quantum theory known as the Casimir Effect, a measurable force that exists between objects inside a vacuum caused by the fluctuations of electromagnetic waves. When studied using classical physics, the vacuum would not produce any force on the objects. However, when looked at using quantum field theory, the vacuum is filled with photons, creating a small but potentially significant force on the objects.

“These studies are important because we are developing nanotechnologies where we’re getting into distances and sizes that are so small that these types of forces can dominate everything else,” said Manjavacas. “We know these Casimir forces exist, so, what we’re trying to do is figure out the overall impact they have very small particles.”

Manjavacas’ research expands on the Casimir effect by developing an analytical expression for the lateral Casimir force experienced by nanoparticles rotating near a flat surface.

Imagine a tiny sphere (nanoparticle) rotating over a surface. While the sphere slows down due to photons colliding with it, that rotation also causes the sphere to move in a lateral direction. In our physical world, friction between the sphere and the surface would be needed to achieve lateral movement. However, the nano-world does not follow the same set of rules, eliminating the need for contact between the sphere and the surface for movement to occur.

“The nanoparticle experiences a lateral force as if it were in contact with the surface, even though is actually separated from it,” said Manjavacas. “It’s a strange reaction but one that may prove to have significant impact for engineers.”

While the discovery may seem somewhat obscure, it is also extremely useful for researchers working in the always evolving nanotechnology industry. As part of their work, Manjavacas says they’ve also learned the direction of the force can be controlled by changing the distance between the particle and surface, an understanding that may help nanotech engineers develop better nanoscale objects for healthcare, computing or a variety of other areas.

For Manjavacas, the project and this latest publication are just another step forward in his research into these Casimir forces, which he has been studying throughout his scientific career. After receiving his Ph.D. from Complutense University of Madrid (UCM) in 2013, Manjavacas worked as a postdoctoral research fellow at Rice University before coming to UNM in 2015.

Currently, Manjavacas heads UNM’s Theoretical Nanophotonics research group, collaborating with scientists around the world and locally in New Mexico. In fact, Manjavacas credits Los Alamos National Laboratory Researcher Diego Dalvit, a leading expert on Casimir forces, for helping much of his work progress.

“If I had to name the person who knows the most about Casimir forces, I’d say it was him,” said Manjavacas. “He published a book that’s considered one of the big references on the topic. So, having him nearby and being able to collaborate with other UNM faculty is a big advantage for our research.”

Here’s a link to and a citation for the paper,

Lateral Casimir Force on a Rotating Particle near a Planar Surface by Alejandro Manjavacas, Francisco J. Rodríguez-Fortuño, F. Javier García de Abajo, and Anatoly V. Zayats. Phys. Rev. Lett. (Vol. 118, Iss. 13 — 31 March 2017) 118, 133605 DOI:https://doi.org/10.1103/PhysRevLett.118.133605 Published 31 March 2017

This paper is behind a paywall.